AUTHOR=Thoma Greg J. , Galina Pantoja Lucina , Linhares Daniel C. L. , Serafini Poeta Silva Ana Paula , Case Lindsay , Knap Pieter W. TITLE=The effects of PRRS on the environmental impact of pig production: a life cycle assessment study JOURNAL=Frontiers in Veterinary Science VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2025.1625581 DOI=10.3389/fvets.2025.1625581 ISSN=2297-1769 ABSTRACT=The Porcine Reproductive and Respiratory Syndrome (PRRS) is a viral pig disease that increases mortality rates and reduces (re)production performance. This worsens a farm’s whole-enterprise feed conversion ratio, which increases its greenhouse gas emission. PRRSV elimination should then result in mitigation of global warming. This study quantifies such mitigation of global warming and of other environmental impact categories such as eutrophication and land use by Life Cycle Assessment. The software package openLCA converted material and energy flows to impact categories of frameworks ReCiPe-2016, PEF-3.1, and IPCC-2021. Flows came from data recorded on 173 PRRS outbreaks in 113 sow farms (1.3 million sows), and on 5,650 all-in-all-out groups of wean-to-finish pigs in 63 farms (26 million pigs). We find that the environmental impact of PRRSV-negative North American farms is 4–6% lower than of the North American industry average (a mix of PRRSV-negative and PRRSV-positive farms), and 9–17% lower than of PRRSV-positive farms.