Commentary: Localized vs. Systematic Neurodegeneration: A Paradigm Shift in Understanding Neurodegenerative Diseases - Norrara, Bianca; Doerl, Jhulimar G.; Guzen, Fausto P.; Cavalcanti, Jose Rodolfo Lopes P.; Freire, Marco Aurelio M. (Frontiers in Systems Neuroscience, 2017)