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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Sports Act. Living</journal-id>
<journal-title>Frontiers in Sports and Active Living</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Sports Act. Living</abbrev-journal-title>
<issn pub-type="epub">2624-9367</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fspor.2024.1385832</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Sports and Active Living</subject>
<subj-group>
<subject>Study Protocol</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>A systematic review protocol of injuries and illness across all the competitive cycling disciplines, including track cycling, mountain biking, road cycling, time trial, cyclocross, gravel cycling, BMX freestyle, BMX racing, e-sport, para-cycling and artistic cycling</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes"><name><surname>Fallon</surname><given-names>Thomas</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref><uri xlink:href="https://loop.frontiersin.org/people/1176997/overview"/><role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author"><name><surname>Heron</surname><given-names>Neil</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
<xref ref-type="author-notes" rid="fn001"><sup>&#x2020;</sup></xref><role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
</contrib-group>
<aff id="aff1"><label><sup>1</sup></label><institution>Centre for Public Health, Queen&#x2019;s University Belfast</institution>, <addr-line>Belfast</addr-line>, <country>Northern Ireland</country></aff>
<aff id="aff2"><label><sup>2</sup></label><institution>Edinburgh Sports Medicine Research Network &#x0026; UK Collaborating Centre on Injury and Illness Prevention in Sport (UKCCIIS)</institution>, <addr-line>Edinburgh</addr-line>, <country>United Kingdom</country></aff>
<aff id="aff3"><label><sup>3</sup></label><institution>School of Medicine, Keele University</institution>, <addr-line>Staffordshire</addr-line>, <country>England</country></aff>
<author-notes>
<fn fn-type="edited-by"><p><bold>Edited by:</bold> Alejandra Polanco, Universit&#x00E9; Gustave Eiffel, France</p></fn>
<fn fn-type="edited-by"><p><bold>Reviewed by:</bold> Howard Hurst, University of Central Lancashire, United Kingdom</p>
<p>Sergio M. Navarro, Mayo Clinic, United States</p></fn>
<corresp id="cor1"><label>&#x002A;</label><bold>Correspondence:</bold> Thomas Fallon <email>tfallon02@qub.ac.uk</email></corresp>
<fn fn-type="other" id="fn001"><label><sup>&#x2020;</sup></label><p>ORCID Neil Heron <ext-link ext-link-type="uri" xlink:href="http://orcid.org/0000-0002-4123-9806">orcid.org/0000-0002-4123-9806</ext-link></p></fn>
</author-notes>
<pub-date pub-type="epub"><day>25</day><month>10</month><year>2024</year></pub-date>
<pub-date pub-type="collection"><year>2024</year></pub-date>
<volume>6</volume><elocation-id>1385832</elocation-id>
<history>
<date date-type="received"><day>13</day><month>02</month><year>2024</year></date>
<date date-type="accepted"><day>10</day><month>10</month><year>2024</year></date>
</history>
<permissions>
<copyright-statement>&#x00A9; 2024 Fallon and Heron.</copyright-statement>
<copyright-year>2024</copyright-year><copyright-holder>Fallon and Heron</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<abstract><sec><title>Introduction</title>
<p>The sport of cycling has witnessed phenomenal growth over the past decade. Globally, over 200 million television hours across five continents watched the recent inaugural World Championships in Glasgow, in 2023. The Union Cycliste Internationale (UCI), the world cycling governing body, has highlighted its mission to &#x201C;<italic>promote and support research in cycling epidemiology and medicine, especially for the benefit of lesser-known disciplines&#x201D;</italic> within its 2030 Agenda. This paper outlines a proposed protocol to conduct a systematic review that comprehensively analyses and synthesises the existing literature about cycling-related injuries and illness across all competitive disciplines.</p>
</sec><sec><title>Methods</title>
<p>The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines will be followed through each stage of this systematic review. Cycling is an umbrella term used for many individual disciplines. Investigation of all types of injuries and/or illnesses sustained during training and/or competition among competitive athletes across all disciplines will be included in this review. A computerised, systematic literature search will be conducted in electronic databases MEDLINE, Scopus, Embase, and Cochrane Library. Independent screening by two reviewers in a two-step process: title/abstract screening followed by full-text review. The reference lists of included articles will be searched to identify any other potentially relevant articles. Narrative synthesis and tabular/charted presentation of the extracted data will be included.</p>
</sec><sec><title>Discussion</title>
<p>This protocol paper outlines the methodology to conduct a systematic review of injuries and illness across all competitive cycling disciplines. The aims of outlining this systematic review protocol are to aid research transparency, help reduce publication bias, prevent selective publication, and prevent the selective reporting of results. Future systematic reviews based on the proposed protocol will summarise the known prevalence, incidences, locations and burden of injury and illness across the sport of cycling.</p>
</sec><sec><title>Trial Registration</title>
<p>This study has been registered with the PROSPERO International Prospective Register of Systematic Reviews (registration number CRD42024502703).</p>
</sec>
</abstract>
<kwd-group>
<kwd>sport</kwd>
<kwd>participation</kwd>
<kwd>elite athletes</kwd>
<kwd>injury</kwd>
<kwd>illness</kwd>
<kwd>cycling</kwd>
<kwd>systematic reviews</kwd>
<kwd>protocol</kwd>
</kwd-group><counts>
<fig-count count="0"/>
<table-count count="5"/><equation-count count="0"/><ref-count count="24"/><page-count count="10"/><word-count count="0"/></counts><custom-meta-wrap><custom-meta><meta-name>section-at-acceptance</meta-name><meta-value>Injury Prevention and Rehabilitation</meta-value></custom-meta></custom-meta-wrap>
</article-meta>
</front>
<body><sec id="s1">
<title/><sec id="s1a"><title>What is already known on this topic</title>
<list list-type="simple">
<list-item><label>&#x2022;</label>
<p>There is a lack of injury and illness epidemiology research within competitive cycling.</p></list-item>
<list-item><label>&#x2022;</label>
<p>In epidemiological studies completed to date, there is a lack of methodology homogeneity around the definitions of injury and illness and reporting standards.</p></list-item>
<list-item><label>&#x2022;</label>
<p>The Union Cycliste Internationale (UCI) Agenda 2030 acknowledges the lack of epidemiological research within cycling. It aims to &#x201C;<italic>promote and support research in cycling epidemiology and medicine, especially for the benefit of lesser-known disciplines&#x201D;.</italic></p></list-item>
</list>
</sec>
<sec id="s1b"><title>What this study adds</title>
<list list-type="simple">
<list-item><label>&#x2022;</label>
<p>This manuscript outlines a protocol that future studies can use to carry out a multidiscipline systematic review of injuries and illness in competitive cycling.</p></list-item>
</list>
</sec>
<sec id="s1c"><title>How this study might affect research, practice, or policy</title>
<list list-type="simple">
<list-item><label>&#x2022;</label>
<p>This protocol can be repeated over time to give an up-to-date understanding of the prevalence of injury and illness within cycling across all competitive disciplines.</p></list-item>
<list-item><label>&#x2022;</label>
<p>Upon completion, studies that follow this proposed protocol will formally highlight the shortcomings in research and provide direction for further research within cycling.</p></list-item>
</list>
</sec>
</sec>
<sec id="s4" sec-type="intro"><title>Introduction</title>
<p>Cycling is a popular and diverse sport, encompassing various disciplines, each with its distinctive demands, environments, and risk factors. Within the sport of cycling, there are ten broad cycling disciplines which break down into 40 subdisciplines of cycling. Globally, over 200 million television hours across five continents were broadcasted during the recent inaugural World Championships in Glasgow 2023 (<xref ref-type="bibr" rid="B1">1</xref>). The sport&#x0027;s phenomenal growth over the past decade has led to an increased focus on the occurrence, patterns and impacts of injuries and illness within different cycling disciplines (<xref ref-type="bibr" rid="B2">2</xref>, <xref ref-type="bibr" rid="B3">3</xref>). Understanding the prevalence and nature of these injuries and illnesses is imperative for enhancing safety measures, injury prevention, and athlete well-being. However, epidemiology research within competitive cycling to date is scarce and lacks methodological homogeneity between studies and disciplines (<xref ref-type="bibr" rid="B4">4</xref>).</p>
<p>The Union Cycliste Internationale (UCI), which is the world governing body for cycling, oversees the regulation of each competitive cycling discipline and the growth of the sport. The UCI has over 1 million members across five continents and holds over 33,000 events per year (<xref ref-type="bibr" rid="B5">5</xref>). As per the 2030 UCI agenda, they highlight the drive to &#x201C;<italic>promote and support research in cycling epidemiology and medicine, especially for the benefit of lesser-known disciplines (epidemiology of medical and trauma pathologies</italic>)&#x201D; (p106) (<xref ref-type="bibr" rid="B5">5</xref>). To date, there has been limited endorsement of such initiatives by the UCI within competitive cycling, which challenges our ability as clinical academics to establish evidence-based injury prevention recommendations and programs.</p>
<p>With the diversity of athletes competing within competitive cycling, across a variety of disciplines, combined with the lack of epidemiological studies, it is unknown what the true prevalence and incidence of injury and/or illness within each discipline is. Indeed, to date, many disciplines have not even been represented within epidemiological research (<xref ref-type="bibr" rid="B4">4</xref>). The International Olympic Committee (IOC) published the first consensus extension for the reporting of injuries within competitive cycling in 2021 (<xref ref-type="bibr" rid="B4">4</xref>). Both the UCI Agenda 2030 (<xref ref-type="bibr" rid="B5">5</xref>) and the IOC consensus (<xref ref-type="bibr" rid="B4">4</xref>) called for action for epidemiology research in the sport, with a particular focus on the disciplines with no research to date.</p>
<p>The preliminary model underpinning injury prevention was proposed by Van Mechelen et al. in 1992 (<xref ref-type="bibr" rid="B6">6</xref>) in a 4-step model starting with injury surveillance. This was further revised by Finch in 2006 with the addition of 2 further steps and the formation of a model known as the TRIPP (Translating Injury Prevention to Practice) model (<xref ref-type="table" rid="T1">Table&#x00A0;1</xref>) (<xref ref-type="bibr" rid="B7">7</xref>). Both models highlight the importance of injury and illness surveillance as the foundation for developing evidence-based injury prevention programmes.</p>
<table-wrap id="T1" position="float"><label>Table 1</label>
<caption><p>Translating research into the injury prevention practice (TRIPP) framework (<xref ref-type="bibr" rid="B7">7</xref>).</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Model Stage Translating Research into the Injury Prevention Practice Framework</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">1 Injury surveillance</td>
</tr>
<tr>
<td valign="top" align="left">2 Establish aetiology and mechanisms of injury</td>
</tr>
<tr>
<td valign="top" align="left">3 Develop preventive measures.</td>
</tr>
<tr>
<td valign="top" align="left">4 &#x201C;Ideal conditions&#x201D;/scientific evaluation</td>
</tr>
<tr>
<td valign="top" align="left">5 Describe the intervention context to inform implementation strategies</td>
</tr>
<tr>
<td valign="top" align="left">6 Evaluate the effectiveness of preventive measures in the implementation context</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>Future studies based on this proposed protocol will enable researchers to uncover commonalities, disparities, and critical gaps in the current knowledge of cycling-related injury and illness epidemiology within each discipline. This paper outlines the methods to conduct a systematic review that comprehensively analyses and synthesizes the existing literature about cycling-related injuries and illness across all competitive disciplines. While individual studies often concentrate on specific disciplines or specific injuries, this review seeks to collate and critically evaluate injury and illness research across all disciplines, including within para-cycling. Completing such research, will act as a foundation in our understanding of where the gaps lie in knowledge and focus our attention on better understanding and preventing injuries and illnesses in competitive cycling (<xref ref-type="bibr" rid="B6">6</xref>).</p>
<sec id="s4a"><title>Aim</title>
<p>To outline a protocol that will enable researchers to identify the prevalence, and incidence of injuries across each of the competitive cycling disciplines which include, track cycling, mountain biking, road cycling, time trial, cyclocross, gravel cycling, BMX freestyle, BMX racing, e-sport, para-cycling and artistic cycling.</p>
</sec>
<sec id="s4b"><title>Objectives</title>
<list list-type="simple">
<list-item><label>1.</label>
<p>To assess the epidemiology of injury across all cycling disciplines.</p></list-item>
<list-item><label>2.</label>
<p>To assess the epidemiology of illness across all cycling disciplines.</p></list-item>
<list-item><label>3.</label>
<p>To identify the differences in definitions and reporting methods of injuries and illnesses across all the cycling disciplines.</p></list-item>
</list>
</sec>
</sec>
<sec id="s5" sec-type="methods"><title>Methods</title>
<sec id="s5a"><title>Study design</title>
<p>Systematic reviews based on the proposed protocol will follow a systematic review study design. The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines will be followed through each stage of this systematic review (<xref ref-type="bibr" rid="B8">8</xref>). Additionally, the PERSiST (implementing Prisma in Exercise, Rehabilitation, Sports Medicine, and SporTs science) document will be used as a guidance tool in developing this protocol and outcomes of focus (<xref ref-type="app" rid="app2">Appendix 2</xref>) (<xref ref-type="bibr" rid="B9">9</xref>).</p>
</sec>
<sec id="s5b"><title>Study registration</title>
<p>The protocol for this systematic review has been registered on the PROSPERO international prospective register for systematic reviews with registration number CRD42024502703.</p>
</sec>
<sec id="s5c"><title>Ethics and dissemination</title>
<p>Ethical approval is not required for systematic review studies that follow this protocol. The intention is to disseminate the findings through a peer-reviewed journal and present them at conferences as well as meetings with key stakeholders in the results, including cyclists and cycling associations.</p>
</sec>
</sec>
<sec id="s6"><title>Criteria for inclusion of studies</title>
<sec id="s6a"><title>Study design</title>
<p>This systematic review protocol includes any study design with the primary focus on injuries and/or illness in competitive cycling disciplines (observational studies, cohort studies, epidemiological studies).</p>
</sec>
<sec id="s6b"><title>Sport context</title>
<p>Cycling is an umbrella term used for many individual disciplines (<xref ref-type="table" rid="T2">Table&#x00A0;2</xref>). Investigation of all types of injuries and/or illnesses sustained during training and/or competition among competitive athletes across all disciplines will be included in this review. All the different cycling disciplines are included in (<xref ref-type="table" rid="T2">Table&#x00A0;2</xref>). To enable the identification of the most frequently occurring injuries and therein derive injury prevention priorities, studies which report only on a specific type of injury (e.g., stress fractures, concussion, external iliac endo fibrosis), illness (gastrointestinal, respiratory) or body part (e.g., head injuries) will be excluded. Studies in recreational cycling (i.e., not competition-based) will also be excluded</p>
<table-wrap id="T2" position="float"><label>Table 2</label>
<caption><p>Description and list of competitive cycling disciplines to be reviewed.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Discipline</th>
<th valign="top" align="center">Subdiscipline</th>
<th valign="top" align="center">Summary</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" rowspan="10">Track Cycling</td>
<td valign="top" align="left">Sprint (SPR)</td>
<td valign="top" align="left">A short-distance race where cyclists compete head-to-head in a velodrome.</td>
</tr>
<tr>
<td valign="top" align="left">Team Sprint (TS)</td>
<td valign="top" align="left">Teams of cyclists compete in a short-distance relay race in a velodrome.</td>
</tr>
<tr>
<td valign="top" align="left">Keirin (KEI)</td>
<td valign="top" align="left">Cyclists follow a pacing motorcycle before sprinting to the finish line in a velodrome.</td>
</tr>
<tr>
<td valign="top" align="left">Individual Pursuit (IP)</td>
<td valign="top" align="left">Two cyclists start on opposite sides of the track, aiming to get the best time over a distance of 3&#x2005;km for female athlete and 4&#x2005;km for males.</td>
</tr>
<tr>
<td valign="top" align="left">Team Pursuit (TP)</td>
<td valign="top" align="left">Teams of four cyclists race against the clock and each other over a set distance of 4&#x2005;km in a velodrome.</td>
</tr>
<tr>
<td valign="top" align="left">Points Race (PR)</td>
<td valign="top" align="left">Cyclists earn points for sprints and laps gained in a long-distance race.</td>
</tr>
<tr>
<td valign="top" align="left">Madison (MAD)</td>
<td valign="top" align="left">Teams of two cyclists take turns racing and resting in a long-distance race where one cyclist hand slings the other in throughout the race.</td>
</tr>
<tr>
<td valign="top" align="left">Omnium (OMN)</td>
<td valign="top" align="left">A multi-race event combining various track cycling disciplines for overall points.</td>
</tr>
<tr>
<td valign="top" align="left">Scratch Race (SCR)</td>
<td valign="top" align="left">A straightforward race where the first cyclist to finish wins.</td>
</tr>
<tr>
<td valign="top" align="left">Time Trial (TT)</td>
<td valign="top" align="left">Cyclists race alone against the clock over a set distance.</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="10">Mountain Biking</td>
<td valign="top" align="left">Cross-Country Olympic (XCO)</td>
<td valign="top" align="left">A mass-start race on a hilly, off-road circuit featuring technical sections.</td>
</tr>
<tr>
<td valign="top" align="left">Cross-Country Marathon (XCM)</td>
<td valign="top" align="left">A long-distance endurance race on off-road terrain.</td>
</tr>
<tr>
<td valign="top" align="left">Cross-Country Short Track (XCC)</td>
<td valign="top" align="left">A shorter, intense version of cross-country racing on a compact circuit.</td>
</tr>
<tr>
<td valign="top" align="left">Cross-Country Eliminator (XCE)</td>
<td valign="top" align="left">A knockout format race with heats on a short, technical course.</td>
</tr>
<tr>
<td valign="top" align="left">Downhill (DHI)</td>
<td valign="top" align="left">Cyclists race individually downhill on a steep, technical course.</td>
</tr>
<tr>
<td valign="top" align="left">Enduro (EDR)</td>
<td valign="top" align="left">A multi-stage race with timed downhill stages and untimed uphill transfers.</td>
</tr>
<tr>
<td valign="top" align="left">Four-Cross (4X)</td>
<td valign="top" align="left">Four cyclists race head-to-head on a downhill course with jumps and berms.</td>
</tr>
<tr>
<td valign="top" align="left">Pump Track</td>
<td valign="top" align="left">A pump track is a track that consists of rollers and steep turns in various sizes and shapes. The rollers and turns are used to generate speed by pumping the bike, not by pedalling</td>
</tr>
<tr>
<td valign="top" align="left">Snow Bike</td>
<td valign="top" align="left">The snow bike is a downhill mountain bike snow event.</td>
</tr>
<tr>
<td valign="top" align="left">E-Mountain Bike (E-MTB)</td>
<td valign="top" align="left">Mountain bike racing using electric-assist bicycles.</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="3">Road Cycling</td>
<td valign="top" align="left">Road Race (RR)</td>
<td valign="top" align="left">A long-distance race on paved roads, typically with a mass start.</td>
</tr>
<tr>
<td valign="top" align="left">Time Trial (TT)</td>
<td valign="top" align="left">Cyclists race alone against the clock over a set distance on paved roads.</td>
</tr>
<tr>
<td valign="top" align="left">Team Time Trial (TTT)</td>
<td valign="top" align="left">Teams of cyclists race against the clock over a set distance on paved roads.</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="2">Trials</td>
<td valign="top" align="left">20-inch (TR-20)</td>
<td valign="top" align="left">Cyclists navigate an obstacle course using a bike with 20-inch wheels.</td>
</tr>
<tr>
<td valign="top" align="left">26-inch (TR-26)</td>
<td valign="top" align="left">Cyclists navigate an obstacle course using a bike with 26-inch wheels.</td>
</tr>
<tr>
<td valign="top" align="left">Cyclocross</td>
<td valign="top" align="left">Cyclocross (CX)</td>
<td valign="top" align="left">Cyclists race on a mixed-terrain course featuring obstacles that may require dismounting.</td>
</tr>
<tr>
<td valign="top" align="left">Gravel Cycling</td>
<td valign="top" align="left">Gravel Race (GR)</td>
<td valign="top" align="left">Long-distance races on gravel and mixed-surface roads.</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="3">BMX</td>
<td valign="top" align="left">BMX Racing (BMX-R)</td>
<td valign="top" align="left">Cyclists race head-to-head on a short, dirt track with jumps and berms.</td>
</tr>
<tr>
<td valign="top" align="left">BMX Freestyle Park (BMX-FP)</td>
<td valign="top" align="left">Riders perform tricks and stunts in a skatepark-like environment.</td>
</tr>
<tr>
<td valign="top" align="left">BMX Freestyle Flatland (BMX-FF)</td>
<td valign="top" align="left">Riders perform tricks on flat ground without ramps or jumps.</td>
</tr>
<tr>
<td valign="top" align="left">E-Sport</td>
<td valign="top" align="left">E-Sport Cycling (ES)</td>
<td valign="top" align="left">Virtual cycling races conducted on online platforms using stationary bikes.</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="6">Para-Cycling</td>
<td valign="top" align="left">Road Race (RR)</td>
<td valign="top" align="left">Para-cyclists compete in a long-distance race on paved roads.</td>
</tr>
<tr>
<td valign="top" align="left">Time Trial (TT)</td>
<td valign="top" align="left">Para-cyclists race alone against the clock over a set distance on paved roads.</td>
</tr>
<tr>
<td valign="top" align="left">Track Cycling (TC)</td>
<td valign="top" align="left">Para-cyclists compete in various track events in a velodrome.</td>
</tr>
<tr>
<td valign="top" align="left">Hand bike (HB)</td>
<td valign="top" align="left">Cyclists with lower limb impairments race using hand-powered bicycles.</td>
</tr>
<tr>
<td valign="top" align="left">Tricycle (TRI)</td>
<td valign="top" align="left">Cyclists with balance impairments race using three-wheeled bicycles.</td>
</tr>
<tr>
<td valign="top" align="left">Tandem (TAN)</td>
<td valign="top" align="left">Visually impaired cyclists race on a tandem bike with a sighted pilot.</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="2">Indoor Cycling</td>
<td valign="top" align="left">Cycle Ball (CB)</td>
<td valign="top" align="left">Teams of two cyclists play a soccer-like game on bicycles.</td>
</tr>
<tr>
<td valign="top" align="left">Artistic Cycling (AC)</td>
<td valign="top" align="left">Cyclists perform gymnastic and dance-like routines on fixed-gear bikes.</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="s6c"><title>Participants</title>
<p>Study inclusion criteria will be framed according to PICO:
<list list-type="simple">
<list-item><label>&#x2022;</label>
<p>Population (P)- Competitive cyclists. Competitive cyclists are those who are partaking in competition at any level. To partake in any competitive event these cyclists will hold a UCI competition licence. Therefore, all athletes included will hold a UCI racing licence affiliated with their National Governing Body (NGB).
<list list-type="simple">
<list-item><label>&#x25CB;</label>
<p>As this study focused on competitive cyclists, we divided this population into three different levels modified from Heron et al. (<xref ref-type="bibr" rid="B10">10</xref>)
<list list-type="simple">
<list-item><label>1.</label>
<p>An amateur is a cyclist, described as one who practices cycling for non-economic reasons and participates in official domestic competitions.</p></list-item>
<list-item><label>2.</label>
<p>An elite cyclist is defined as a cyclist who competes at the national/international level but does not receive a regular salary or income for their involvement in the sport.</p></list-item>
<list-item><label>3.</label>
<p>A Professional Cyclist is defined as a cyclist who competes at the national/international level and receives a regular salary or income for their involvement in the sport.</p></list-item>
</list></p></list-item>
</list></p></list-item>
<list-item><label>&#x2022;</label>
<p>The intervention (I) will be classed as injury and/or illness or exposure to injury and or illness. This may be in one event, one month, one competitive season or one year.</p></list-item>
<list-item><label>&#x2022;</label>
<p>Comparator (C)- Not applicable</p></list-item>
<list-item><label>&#x2022;</label>
<p>Outcome (O)&#x2014;The outcome of interest in the studies will be injury/illness type and exposure rate.</p></list-item>
</list></p>
</sec>
<sec id="s6d"><title>Search methods for identification of studies</title>
<p>A computerised, systematic literature search will be conducted in electronic databases MEDLINE and Embase (both via Ovid), Scopus and Cochrane Library. In line with recommendations for systematic reviews (<xref ref-type="bibr" rid="B11">11</xref>) on measurement properties, a hand search of the reference lists of included studies and relevant reviews for additional sources will be conducted. A grey literature search in Google Scholar will also be performed following the database searches.</p>
</sec>
<sec id="s6e"><title>Search strategy</title>
<p>The presented search strategy was reviewed and approved by a medical librarian at Queens University Belfast. The search strategies will be based on keywords broken down into those related to cycling and those related to injury and illness (<xref ref-type="table" rid="T3">Table&#x00A0;3</xref>). Results obtained from the searches will be downloaded in RIS format.</p>
<table-wrap id="T3" position="float"><label>Table 3</label>
<caption><p>Keywords used in search strategy.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Cycling Discipline/population Keywords</th>
<th valign="top" align="center">Injury &#x0026; Illness Keywords</th>
<th valign="top" align="center">Medical Subject Headings (MeSH) Terms:</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Road cycling</td>
<td valign="top" align="left">Sports injuries</td>
<td valign="top" align="left">&#x201C;Bicycling injuries&#x201D;</td>
</tr>
<tr>
<td valign="top" align="left">Track cycling</td>
<td valign="top" align="left">Trauma</td>
<td valign="top" align="left">&#x201C;Athletic Injuries&#x201D;</td>
</tr>
<tr>
<td valign="top" align="left">Mountain biking</td>
<td valign="top" align="left">Overuse injuries</td>
<td valign="top" align="left">&#x201C;Wounds and Injuries&#x201D;</td>
</tr>
<tr>
<td valign="top" align="left">Cyclocross</td>
<td valign="top" align="left">Musculoskeletal injuries</td>
<td valign="top" align="left" rowspan="12"/>
</tr>
<tr>
<td valign="top" align="left">BMX racing</td>
<td valign="top" align="left">Health surveillance</td>
</tr>
<tr>
<td valign="top" align="left">Time trial</td>
<td valign="top" align="left">Illness surveillance</td>
</tr>
<tr>
<td valign="top" align="left">Gravel cycling</td>
<td valign="top" align="left">Injury surveillance</td>
</tr>
<tr>
<td valign="top" align="left">Para-Cycling</td>
<td valign="top" align="left">Epidemiology</td>
</tr>
<tr>
<td valign="top" align="left">BMX freestyle</td>
<td valign="top" align="left" rowspan="7"/>
</tr>
<tr>
<td valign="top" align="left">Artistic cycling</td>
</tr>
<tr>
<td valign="top" align="left">E-Sport cycling</td>
</tr>
<tr>
<td valign="top" align="left">Bicycle racing</td>
</tr>
<tr>
<td valign="top" align="left">Competitive cycling</td>
</tr>
<tr>
<td valign="top" align="left">Elite cycling</td>
</tr>
<tr>
<td valign="top" align="left">Professional cycling</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>Using Boolean operators (AND, OR), we will combine Cycling and Injury/Illness keywords. For example: (&#x201C;Competitive cycling&#x201D; OR &#x201C;Road cycling&#x201D;). Using the term &#x201C;AND&#x201D; we will combine cycling keywords and injury/illness keywords. Example (&#x201C;Sports injuries&#x201D; OR &#x201C; Musculoskeletal injuries&#x201D; AND &#x201C;Elite Cycling&#x201D; OR &#x201C;Competitive cycling&#x201D;).</p>
</sec>
<sec id="s6f"><title>Study selection process</title>
<p>References exported from each database will be imported onto the AI systematic review software &#x201C;Rayyan&#x201D; (Cambridge, Massachusetts, USA), where duplicates will be removed and made available for screening. Independent screening by two reviewers will be undertaken in a two-step process: title/abstract screening, followed by full-text review. The reference lists of included articles will be searched to identify any other potentially relevant articles. In addition, citation tracking will also be used to identify potentially eligible studies. Reviewers will apply the predefined inclusion and exclusion criteria to determine study eligibility. A third reviewer will be consulted to resolve disagreements amongst these reviewers and to facilitate consensus. Once study consensus is reached, references will be transferred to the Mendeley reference manager for write-up.</p>
</sec>
<sec id="s6g"><title>Data extraction</title>
<p>Systematic extraction of relevant data elements including the following information listed in (<xref ref-type="app" rid="app1">Appendix 1</xref>). Double verification of extracted data will be completed by the second reviewer to ensure accuracy and completeness. Extracted data will be inputted into a proposed build Microsoft Excel sheet, with all raw data being published within the appendix of the study.</p>
</sec>
<sec id="s6h"><title>Methodological quality assessment</title>
<p>Studies will be independently assessed by two reviewers using the National Institute of Health Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies to determine study quality (<xref ref-type="bibr" rid="B12">12</xref>) (<xref ref-type="app" rid="app2">Appendix 2</xref>). The proportion of questions labelled &#x201C;<italic>yes</italic>&#x201D; will be calculated with the higher score indicating a lower risk of bias.</p>
</sec>
<sec id="s6i"><title>Synthesis of results</title>
<p>Collation of findings from included studies will be done using a narrative approach to present a coherent summary of the evidence. A Tabular/charted presentation of the extracted data will be included where possible. The variables of injuries mainly will be main injury/illness types and definitions, event category, level of participation, diagnostic categories (ie. Medical professionals or self-reported etc), in competition/out of competition and time lost. Statistical methods such as a meta-analysis to combine data if studies are homogenous and comparable. Two systematic reviews have been completed in cycling injury epidemiology, one focused on road cycling (<xref ref-type="bibr" rid="B2">2</xref>) and the other on MTB (<xref ref-type="bibr" rid="B3">3</xref>). Both reviews were unable to complete any statistical analysis between studies due to the lack of homogeneity between studies. The determination for such an analysis will be at the discretion of the authors, with appropriate statistical input, contingent upon their assessment of discernible dissimilarities among study subpopulations (such as international, elite, and amateur cohorts), exposure types (per 1000hrs, 100rides,100 riders), and reported outcome metrics. This decision-making process aligns with the guidelines advocated by Higgins and Green and Borenstein et al. (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B14">14</xref>). As per the IOC consensus statement extension for the reporting of injuries and illness in cycling. Meta-analysis of injury and illness rates between disciplines will present rates per 365 athlete days which will allow for comparison of injury and illness rates between cycling disciplines (<xref ref-type="bibr" rid="B4">4</xref>).</p>
</sec>
</sec>
<sec id="s7" sec-type="discussion"><title>Discussion</title>
<p>Injury and illness epidemiology has been identified as a topic of focus for the UCI within their recently published Agenda 2030 (<xref ref-type="bibr" rid="B5">5</xref>). This manuscript outlines a protocol to conduct a systematic review of injuries and illness across the different cycling disciplines. The aim of carrying out such research is to present the injury and illness types seen in cycling, their known prevalence, incidences, locations, and burden of injury and illness across the sport of cycling. This systematic review protocol differs from others in injury and illness epidemiology as it will present data from a range of different competitive cycling disciplines. As outlined within the methods and in the IOC consensus statement extension studies with methodological homogeneity will be included within a meta-analysis in which injury rates will be presented per 365 athlete days to allow for comparison between disciplines. In line with the growth of the sport and ensuring that the health and safety of athletes are optimised, the findings of this review will focus on the direction of further high-quality prospective injury and illness studies. From this review, we will aim to gain an understanding of the breadth of injuries and illness across the sport. This will enable researchers to focus future research on areas of most need and align with the 2030 UCI agenda aims to &#x201C;<italic>promote and support research in cycling epidemiology and medicine, especially for the benefit of lesser-known disciplines&#x201D;</italic> (<xref ref-type="bibr" rid="B5">5</xref>).</p>
<p>Studies have shown that cyclists are not immune to injury or illness (<xref ref-type="bibr" rid="B2">2</xref>, <xref ref-type="bibr" rid="B15">15</xref>&#x2013;<xref ref-type="bibr" rid="B19">19</xref>). The range of injuries and illnesses that do occur is vast, however, the reporting of injuries varies significantly with a significant lack of homogeneity between studies and disciplines (<xref ref-type="bibr" rid="B2">2</xref>, <xref ref-type="bibr" rid="B4">4</xref>). Injury and Illness surveillance studies in other sports are far more advanced and have seen the development of specific warm-up routines to reduce injury risk such as FIFA 11 (<xref ref-type="bibr" rid="B20">20</xref>) in soccer, and Gaelic Athletic Association (GAA) 15 (<xref ref-type="bibr" rid="B21">21</xref>) in Gaelic games. Injury and illness surveillance has also been the mainstay in providing evidence that underpins the rule changes to tackle height and reduce head injury risk in professional (<xref ref-type="bibr" rid="B22">22</xref>) and amateur (<xref ref-type="bibr" rid="B23">23</xref>) rugby. Such examples in other sports highlight the importance of injury surveillance in cycling for medical professionals within teams to adopt the TRIPP model and inform practices that reduce overall injuries and illnesses amongst cyclists. Furthermore, such data on competitive cycling would support the UCI in achieving their agenda 2030 objectives 2(a) &#x201C;reducing accident risk&#x201D; and 2 (e) &#x201C;Implementing independent regulatory medical monitoring&#x201D;. This review protocol aims to aid research transparency, helping reduce publication bias, preventing selective publication and selective reporting of results. Subsequently, the outcome of this review will provide researchers and sports medicine practitioners with the first step in understanding the current injury and illness surveillance evidence across all cycling disciplines. It will highlight disciplines which lack injury and illness surveillance research in addition to directing the focus for further injury surveillance research amongst the sport.</p>
</sec>
</body>
<back>
<sec id="s9" sec-type="author-contributions"><title>Author contributions</title>
<p>TF: Writing &#x2013; original draft, Writing &#x2013; review &#x0026; editing. NH: Writing &#x2013; original draft, Writing &#x2013; review &#x0026; editing.</p>
</sec>
<sec id="s10" sec-type="funding-information"><title>Funding</title>
<p>The author(s) declare financial support was received for the research, authorship, and/or publication of this article. TF is funded by the Department for Education (DfE). No other funding was received for this study.</p>
</sec>
<sec id="s11" sec-type="COI-statement"><title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="s12" sec-type="disclaimer"><title>Publisher&#x0027;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
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<app-group>
<app id="app1"><title>Appendix 1: Data Extraction Sheet.</title>
<table-wrap id="T4" position="float">
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left" colspan="2">Date</th>
<th valign="top" align="center">Study 1 Example</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" colspan="2">Title</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Authors</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Source</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Study Design</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Inclusion criteria</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Exclusion criteria</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Definition of injury</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Definition of illness</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Definition of severity</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Injuries Diagnosed by</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">IOC Classification (Y/N)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Name of event</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">UCI Classification</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Length of event (days)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Distance of events</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Injuries/Illness Excluded</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Comment</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Type of cycling Event:</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Discipline</td>
<td valign="top" align="left">Sub-Discipline</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" rowspan="10">Track Cycling</td>
<td valign="top" align="left">Sprint (SPR)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Team Sprint (TS)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Keirin (KEI)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Individual Pursuit (IP)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Team Pursuit (TP)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Points Race (PR)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Madison (MAD)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Omnium (OMN)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Scratch Race (SCR)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Time Trial (TT)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" rowspan="10">Mountain Biking</td>
<td valign="top" align="left">Cross-Country Olympic (XCO)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Cross-Country Marathon (XCM)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Cross-Country Short Track (XCC)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Cross-Country Eliminator (XCE)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Downhill (DHI)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Enduro</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Four-Cross (4X)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Pump Track</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Snow Bike</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">E-Mountain Bike (E-MTB)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" rowspan="3">Road Cycling</td>
<td valign="top" align="left">Road Race (RR)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Time Trial (TT)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Team Time Trial (TTT)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" rowspan="2">Trials</td>
<td valign="top" align="left">20-inch (TR-20)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">26-inch (TR-26)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Cyclocross</td>
<td valign="top" align="left">Cyclocross (CX)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Gravel Cycling</td>
<td valign="top" align="left">Gravel Race (GR)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" rowspan="3">BMX</td>
<td valign="top" align="left">BMX Racing (BMX-R)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">BMX Freestyle Park (BMX-FP)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">BMX Freestyle Flatland (BMX-FF)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">E-Sport</td>
<td valign="top" align="left">E-Sport Cycling (ES)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" rowspan="6">Para-Cycling</td>
<td valign="top" align="left">Road Race (RR)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Time Trial (TT)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Track Cycling (TC)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Hand bike (HB)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Tricycle (TRI)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Tandem (TAN)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" rowspan="2">Indoor Cycling</td>
<td valign="top" align="left">Cycle Ball (CB)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Artistic Cycling (AC)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Number of Injuries</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Injuries M</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Injuries Fm</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Single Site Injury</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Double Site Injury</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">3 Or More</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">not listed</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Number of Ilnness</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Neuromuscular Disorder</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Injuries per Incident</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Number of participants M</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Number of participants F</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Total</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Total Exposure</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Days</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Hours</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Racing</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Injury rate (&#x0025;) M</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Injury rate (&#x0025;) FM</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Injury rate (&#x0025;) overall</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">illness overall</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Type of injury</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Skin&#x2014;laceration/abrasion/skin lesion</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Muscle&#x2014;strain grade 1 or 2</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Ligament&#x2014;sprain grade 1 or 2</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Muscle&#x2014;contusion/hematoma</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Muscle&#x2014;cramps or spasms</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Tendon&#x2014;tendinopathy/tendinosis/tendinitis</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Joint&#x2014;arthritis/synovitis/bursitis</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Bone&#x2014;contusion</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Tendon&#x2014;fasciitis/aponeurosis injury</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Joint&#x2014;dislocation/subluxation/instability</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Other injury (assessment note required)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Bone&#x2014;acute fracture</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Neuro&#x2014;concussion</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Joint&#x2014;lesion of meniscus or cartilage</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Joint&#x2014;impingement</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Tendon&#x2014;sprain grade 1 or 2</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">n/a</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Ligament&#x2014;rupture grade 3</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Muscle&#x2014;rupture grade 3</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Bone&#x2014;stress fracture/stress reaction</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Neuro&#x2014;peripheral nerve injury</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Tendon&#x2014;rupture grade 3</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Neuro&#x2014;spinal cord injury</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Injury without tissue type specified</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Area of injury</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Pelvis</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Hip</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Anterior thigh</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Posterior thigh</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Knee</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Anterior lower leg</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Posterior lower leg</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Calf/Achilles</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Foot/toes</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Ankle</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Shoulder</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Upper arm</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Elbow</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Forearm</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Wrist</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Hand/fingers</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Thumb</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Face (including eyes, ears, nose)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Head</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Neck</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Chest</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Abdomen</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Thoracic</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Upper back</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Lower back</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Back</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Multiple body locations</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Dental</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">n/a</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Upper extremity</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Lower</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Head/neck</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Torso/back</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Multiple sites</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Combined limb</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Able to continue cycling: Yes (&#x0025;)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Able to continue cycling: No</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Severity of injuries Overall</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Severity of injuries M</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Severity of injuries FM</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Types of Illness</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Dermatologic</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Thermoregulatory</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Respiratory/ear, nose, throat</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Gastro-intestinal</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Other</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Uro-genital/gynaecological</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Neurological/psychiatric</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Cardiovascular</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Dental</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Allergic/immunological</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Musculoskeletal</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Metabolic/endocrinological</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Haematological</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Aetiology</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Allergic</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Environmental&#x2013;exercise-related</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Environmental&#x2014;non-exercise</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Immunological/inflammatory</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Infection</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Neoplasm</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Metabolic/nutritional</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Thrombotic/haemorrhagic</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Degenerative or chronic condition</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Developmental anomaly</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Drug-related/poisoning</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Multiple</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">n/a</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Unknown, or not specified</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Contributing factors reported?</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Acute (&#x0025;)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Chronic (&#x0025;)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Contact (with another athlete)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Non-contact trauma</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Overuse (sudden onset)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Overuse (gradual onset)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Contact (with stagnant object)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Contact (with moving object)</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Recurrence of previous injury</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Other cause not otherwise specified</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Other</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">n/a</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Field of Play conditions</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Equipment failure</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Weather conditions</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Violation of rules</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" colspan="2">Rider related fault</td>
<td valign="top" align="left"/>
</tr>
</tbody>
</table>
</table-wrap></app><app id="app2"><title>Appendix 2: National Institute of Health Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies to determine study quality.</title>
<table-wrap position="anchor">
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Criteria</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>1.</label>
<p>Was the research question or objective in this paper clearly stated?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>2.</label>
<p>Was the study population clearly specified and defined?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>3.</label>
<p>Was the participation rate of eligible persons at least 50&#x0025;?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>4.</label>
<p>Were all the subjects selected or recruited from the same or similar populations (including the same time period)? Were inclusion and exclusion criteria for being in the study prespecified and applied uniformly to all participants?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>5.</label>
<p>Was a sample size justification, power description, or variance and effect estimates provided?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>6.</label>
<p>For the analyses in this paper, were the exposure(s) of interest measured prior to the outcome(s) being measured?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>7.</label>
<p>Was the timeframe sufficient so that one could reasonably expect to see an association between exposure and outcome if it existed?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>8.</label>
<p>For exposures that can vary in amount or level, did the study examine different levels of the exposure as related to the outcome (e.g., categories of exposure, or exposure measured as continuous variable)?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>9.</label>
<p>Were the exposure measures (independent variables) clearly defined, valid, reliable, and implemented consistently across all study participants?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>10.</label>
<p>Was the exposure(s) assessed more than once over time?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>11.</label>
<p>Were the outcome measures (dependent variables) clearly defined, valid, reliable, and implemented consistently across all study participants?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>12.</label>
<p>Were the outcome assessors blinded to the exposure status of participants?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>13.</label>
<p>Was loss to follow-up after baseline 20&#x0025; or less?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">
<list list-type="simple">
<list-item><label>14.</label>
<p>Were key potential confounding variables measured and adjusted statistically for their impact on the relationship between exposure(s) and outcome(s)?</p></list-item>
</list></td>
</tr>
<tr>
<td valign="top" align="left">Total percentage of applicable questions answered &#x201C;Y&#x201D;</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="table-fn1"><p>&#x002A;Y, Yes; N, No; N/A, not applicable.</p></fn>
</table-wrap-foot>
</table-wrap></app>
</app-group>
</back>
</article>