AUTHOR=Neri Alberto , Penza Veronica , Haouchine Nazim , Mattos Leonardo S. TITLE=Benchmarking complete-to-partial point cloud registration techniques for laparoscopic surgery JOURNAL=Frontiers in Robotics and AI VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/robotics-and-ai/articles/10.3389/frobt.2025.1702360 DOI=10.3389/frobt.2025.1702360 ISSN=2296-9144 ABSTRACT=ObjectiveRegistering a preoperative 3D model of an organ with its actual anatomy viewed from an intraoperative video is a fundamental challenge in computer-assisted surgery, especially for surgical augmented reality. To address this, we present a benchmark of state-of-the-art deep learning point-cloud registration methods, offering a transparent evaluation of their generalizability to surgical scenarios and establishing a robust guideline for developing advanced non-rigid algorithms.MethodsWe systematically evaluate traditional and deep learning GMM-based, correspondence-based, correspondence-free, matching-based, and liver-specific point cloud registration approaches on two surgical datasets: a deformed IRCAD liver set and DePoll dataset. We also propose our complete-to-partial point cloud registration framework that leverages keypoint extraction, overlap estimation, and a Transformer-based architecture, culminating in competitive registration results.ResultsExperimental evaluations on deformed IRCAD tests reveal that most deep learning methods achieve good registration performances with TRE<10 mm, MAE(R) < 4 and MAE(t)<5 mm. On DePoll, however, performance drops dramatically due to the large deformations.ConclusionIn conclusion, deep-learning rigid registration methods remain reliable under small deformations and varying partiality but lose accuracy when faced with severe non-rigid changes. To overcome this, future work should focus on building non-rigid registration architectures that preserve the strengths of self-, cross-attention and overlap modules while enhancing correspondence estimation to handle large deformations in laparoscopic surgery.