Technology transfer is defined as the process of transferring knowledge, innovations, and scientific developments that have been generated in academic institutions, research centers, and private enterprises to the manufacturing sector for practical application. This mechanism plays a crucial role in economic development by driving innovation, strengthening business competitiveness, and contributing to the sustainability of long-term growth (Donneys González and Blanco Campins, 2016). In a global environment characterized by the knowledge economy, a country's capacity to adopt and apply new technologies determines its position in international markets and its ability to respond to contemporary productive and social challenges.

In Colombia, technology transfer has been promoted through various strategies and policies formulated by the Ministry of Science, Technology, and Innovation (MinCiencias), in collaboration with other government entities and stakeholders in the innovation system. A number of initiatives have been implemented, including the establishment of research results transfer offices (OTRIs), technology parks, and incentive programs designed to enhance collaboration between academia and the productive sector. Nevertheless, despite these efforts, limitations in the coordination between the actors involved persist, which reduces the effectiveness of these policies (Rivero et al., 2016).

The Colombian context is confronted with numerous challenges in the realm of technology transfer. Investment in research and development (R&D) remains inadequate, while the incentives for innovation are deemed to be inadequate. Moreover, the presence of bureaucratic barriers has been identified as a significant impediment to effective collaboration between institutions and companies. The prevailing culture of collaboration remains underdeveloped (Castro Bermúdez and Murcia González, 2024). Significant lags in innovation have been identified within strategic sectors such as manufacturing and agriculture, which in turn negatively impacts their efficiency and competitiveness (Arangüena Delaude, 2024).

The overcoming of these obstacles is essential to the consolidation of a robust innovation system and the optimisation of technology transfer processes in the country. Technology transfer is of fundamental importance to a nation's economic development and competitiveness, facilitating the transformation of scientific and technological advances generated in academic and research institutions into innovations that are then applied in the productive sector. In Colombia, this process is confronted by numerous challenges that impede the establishment of a connection between knowledge generation and its implementation in industry. Despite the efforts of institutions to strengthen the relationship between academia and the productive sector, there are still significant gaps that limit the effectiveness of these efforts (Galvez Grados and Herrera Quispe, 2020).

One of the primary obstacles pertains to the absence of clearly defined and sustainable policies that would encourage cooperation between universities, research centers, and companies. The absence of adequate incentives for researchers and entrepreneurs has engendered an environment in which technology transfer is not regarded as a strategic priority (Pérez Botero, 2016). Moreover, the complexity of bureaucracy and the intricacies of administrative processes can impede the formalization of collaboration agreements, consequently delaying the implementation of innovations in the market. From an economic perspective, Colombia's comparatively low investment in research and development (R&D) relative to other countries in the region restricts companies' capacity to assimilate and apply novel technologies. It is evident that small and medium-sized enterprises (SMEs) are particularly deficient in the financial and human resources required to adopt technological innovations, thereby creating a significant disparity between scientific knowledge and its practical application. Moreover, the diminution in the budget of the Ministry of Science, Technology, and Innovation (MinCiencias) signifies an added challenge for the development of innovation in the nation (Flores Rueda et al., 2024).

From a cultural perspective, the absence of collaboration between the academic and business sectors has engendered a pervasive mistrust and a reluctance to engage in cooperative endeavors. While companies may perceive academic research as not aligning with their objectives, researchers may harbor reservations regarding the involvement of the private sector in their research endeavors. This disconnection has been identified as a factor hindering the formation of strategic alliances and the implementation of successful technology transfer models (Vargas Nossa, 2021).

Systematic literature reviews are a rigorous and replicable methodology for organizing, evaluating, and synthesizing existing knowledge on a specific topic. They are fundamental to consolidating scientific agendas and supporting evidence-based decision-making. According to Bangdiwala (2024), such reviews facilitate the identification of patterns, knowledge gaps, and levels of evidence in fields characterized by abundant academic production but fragmented research, thereby contributing to the design of more effective public policies and intervention strategies. In contexts such as Colombia, where technology transfer processes encounter structural impediments, a systematic review provides a comprehensive overview and facilitates the establishment of research priorities that are aligned with national needs.

Beyond knowledge synthesis, systematic reviews foster cooperation among researchers, institutions, and productive sectors by providing a common reference framework. Arani et al. (2024) emphasize that these reviews not only consolidate the state of the art but also enable new lines of collaborative research by identifying emerging methodological approaches and areas of opportunity. In the domain of innovation and technology transfer, this instrument integrates dispersed evidence, assesses the effectiveness of implemented policies, and proposes adaptive models tailored to specific territorial and sectoral contexts.

In this vein, the present study employs a systematic review not only as a rigorous methodological approach but also as a means to enhance the articulation between science, technology, and society in Colombia. By underscoring the institutional, economic, and cultural factors that influence technology transfer, this research endeavors to contribute to the formulation of a shared agenda that promotes more inclusive, context-sensitive, and sustainable innovation.

Despite the fact that a number of studies have been conducted on the subject of technology transfer in Colombia, there are still significant gaps in the literature regarding the specific dynamics that limit its effectiveness. The majority of research in this field has been concerned with the innovation system in general terms, rather than exploring the specific structural factors that impede the integration of scientific knowledge into the productive sector. Despite the investment of time and resources by universities and research centers, the results do not always meet expectations due to insufficient funding for innovation and a lack of adequate incentives within academic institutions (Galvez Grados and Herrera Quispe, 2020). It is imperative to undertake a thorough analysis of the prevailing challenges and formulate strategies to address this discrepancy, thereby promoting more efficient and sustainable technology transfer in Colombia.

In this regard, the objective of this research is to analyse the dynamics and challenges affecting technology transfer in Colombia, identifying institutional, economic, and cultural factors that limit its effectiveness and sustainability. In order to achieve this objective, a series of questions are posed in order to analyse the dynamics and challenges affecting technology transfer in Colombia.

Although previous studies have addressed the topic of technology transfer in Colombia, most have focused on general analyses of innovation systems or on isolated institutional experiences, without offering a comprehensive view of the structural factors that hinder effective knowledge transfer to the productive sector (Donneys González and Blanco Campins, 2016; Rivero et al., 2016). Unlike these fragmented approaches, this study offers a systematic review that integrates institutional, economic, and cultural perspectives, based on the PRISMA 2020 methodology. This allows for a more robust identification of barriers and opportunities, as well as the proposal of differentiated and context-sensitive strategies. By bridging existing knowledge gaps and highlighting the relevance of regional dynamics, this research contributes a more holistic understanding of the challenges and opportunities for strengthening technology transfer in Colombia.

The research employs the PRISMA 2020 methodology (Preferred Reporting Items for Systematic Reviews and Meta-Analyses), an internationally recognized framework that enhances transparency, comprehensiveness, and reproducibility in systematic reviews (Page et al., 2021). This approach provides a rigorous and standardized structure for identifying, selecting, evaluating, and synthesizing relevant scientific studies—particularly valuable in contexts where the available evidence is fragmented, such as technology transfer in countries with diverse institutional and innovation capacities.

The implementation of PRISMA ensures methodological rigor and reduces bias, which is essential for accurately characterizing the institutional, economic, and cultural dynamics that shape technology transfer in Colombia. Furthermore, this protocol enables the comparison of results with studies conducted in other Latin American countries, such as Mexico, Peru, and Argentina, where analogous structural challenges exist, including limited R&D investment, fragmented innovation ecosystems, and weak university–industry collaboration. The increased utilization of PRISMA in the region has resulted in the establishment of a shared methodological foundation for the development of regional research agendas and the promotion of context-sensitive scientific cooperation.

The results were organized according to the research questions, thus facilitating a structured analysis of the dynamics and challenges affecting technology transfer in Colombia. This structure facilitated the identification of institutional, economic, and cultural factors that were limiting the process, along with the relevant strategies and policies for strengthening them. The findings were constructed from the analysis of specialized literature and selected case studies. Table 1 presents a summary of the studies included in the analysis.

As illustrated in Figure 2, the primary institutional impediments impeding university-business collaboration in technology transfer processes in Colombia are evident. The text highlights institutional capacity limitations with six mentions, followed by hierarchical decision-making structures (Arangüena Delaude, 2024), knowledge transfer models (Castro Bermúdez and Murcia González, 2024), agricultural sector barriers (Castro Bermúdez and Murcia González, 2024), and organizational learning deficits (Castro Bermúdez and Murcia González, 2024). Other barriers include intellectual property culture, system vulnerability factors, cultural and epistemic gaps, as well as aspects related to policies, incentives, and regional governance, each with a lower frequency.

As illustrated in Figure 3, the primary aspects associated with investment in research and development (R&D) and its repercussions on technology transfer in Colombia are outlined. The most frequently referenced subjects are technology transfer channels (six mentions) and investment in agricultural technology (five). It is evident that the following elements are of particular significance in this context: firstly, the support for learning processes (Castro Bermúdez and Murcia González, 2024); secondly, the risks of foreign dependence (Rivero et al., 2016); thirdly, the knowledge management tools (Rivero et al., 2016); fourthly, the real-time management (Rivero et al., 2016); fifthly, the infrastructure for research and consulting (Rivero et al., 2016); and sixthly, the individual mentions of R&D investment levels, sector allocation, and regional innovation policies.

As illustrated in Figure 4, the primary components associated with organizational culture within the context of technology perception and adoption are delineated. The study's key findings are as follows: firstly, the adoption of agricultural technology; secondly, technology perception patterns; thirdly, food security dynamics; and finally, the empowerment of small farmers. The following factors were also identified: cross-cultural adaptation, climate change strategies, integration of advanced knowledge, knowledge transfer practices, community learning models, and learning efficiency.

Figure 5 identifies effective strategies derived from international experiences that can be adapted to the Colombian context in order to strengthen technology transfer. The findings of the study include knowledge-based learning, inclusive technology adoption, and adapted management models. A plethora of additional features have been identified, including, but not limited to, joint research initiatives, climate adaptation measures, real-time monitoring, transnational collaboration networks, evidence-based assessment, as well as hybrid technology transfer office (TTO) models and open innovation strategies.

As illustrated in Figure 6, the systematic review has identified the primary components of government policies that have contributed to technological strengthening in Colombia. The results of the study highlight the importance of legislative frameworks, support for agricultural innovation, and social welfare programs. In addition, policies for collaborative action, international financing, bilateral cooperation, climate change adaptation, environmental conservation initiatives, inclusive innovation systems, and evidence-based assessment mechanisms are identified, reflecting a comprehensive approach to the formulation of public policies aimed at technology transfer.

This section discusses the findings of the study on the dynamics and challenges of technology transfer in Colombia. The main patterns identified are interpreted based on the theoretical framework and the national context. The results of the present study are then compared with those of previous studies conducted in Colombia and other countries, with a view to highlighting both similarities and differences between them, and identifying any gaps in the research. The results obtained have enabled the formulation of a conceptual framework, the purpose of which is to summarize the critical factors of the process. The study's theoretical, policy, and practical implications are also presented, its limitations are identified, and future research is proposed.

This study on the dynamics and challenges of technology transfer in Colombia presents methodological limitations that must be acknowledged to strengthen its scientific soundness. The qualitative approach facilitated detailed exploration; however, it limits the possibility of extrapolating the results to other settings. The data collection process encompassed interviews and a comprehensive documentary analysis. However, it is important to acknowledge the inherent subjectivity of this analysis, which is contingent on the disposition, context, and interpretation of the participants.

This can result in the introduction of biases associated with individual experiences or institutional structures. The analysis concentrated on representative cases, without providing a comprehensive overview of all regions or sectors. The absence of quantitative data impeded the establishment of direct relationships between variables such as investment, productivity, or social impact. Technology transfer is a dynamic process; therefore, the findings should be understood as an approximation situated in a specific time and place. The identification of these limitations enables the development of new research avenues that complement, deepen, and contrast the results obtained.

One important limitation of this study concerns the formulation of the search equation used in the systematic review. The query included only English-language terms such as “technology transfer” and “knowledge transfer,” excluding potentially relevant results that could have been retrieved using equivalent Spanish terms such as “innovación” or “colaboración universidad-empresa.” Additionally, the absence of a defined temporal window may have affected the scope of the analysis, particularly given the growth in indexed publications on Colombia since 2005. Expanding the search to include Spanish-language terms and a time-based filter would likely yield a broader corpus of studies; however, such changes would require a complete restructuring of the methodology and were therefore acknowledged as a methodological limitation rather than implemented in the present study.

The results, implications, and limitations identified in this study allow us to propose new lines of research to further investigate technology transfer in Colombia. A priority line of enquiry involves the undertaking of comparative studies between regions exhibiting varying degrees of institutional development, research and development capacities, and levels of coordination between universities, businesses, and communities. This approach facilitates the identification of differential factors that explain variability in transfer processes and allows us to extract useful lessons for contexts with less maturity in innovation.

Furthermore, there is a necessity to advance longitudinal studies that analyze the evolution of inter-institutional links, the effects of sustained investment in science and technology, and the cumulative results of implemented public policies. This perspective facilitates the overcoming of a static view and the observation of processes of learning, adaptation, and institutional transformation. Another relevant line of research proposes the use of mixed methodologies that integrate qualitative and quantitative data. The proposal entails the conceptualization of specific indicators to assess the effectiveness of technology transfer offices, the social impact of adopted innovations, and the return on investment in collaborative projects. These tools facilitate the establishment of relationships between variables such as investment, productivity, technological appropriation and territorial sustainability.

In addition, further investigation is required into the processes of cultural, epistemic, and organizational mediation that influence transfer. This analysis encompasses the examination of the negotiation of meanings, the adaptation of technologies, and the establishment of relationships of trust between actors with divergent logics. It is recommended that the integration of traditional knowledge and scientific knowledge, as well as the co-creation models present in rural and peri-urban contexts, be explored in greater detail. In conclusion, the proposal is made for the study to be undertaken of the development of institutional and human capacities that are necessary for effective transfer.

This field encompasses the analysis of training practices, organizational learning mechanisms, and collaborative leadership strategies within universities, companies, and innovation centers. Addressing these dimensions enables a more comprehensive and situated approach, consistent with the country's structural and territorial challenges. These research lines serve to consolidate the academic field, whilst concurrently proffering pertinent elements for the design of public policies and knowledge-based development strategies.

The phenomenon of technology transfer in Colombia must be considered as a socio-political process, rather than a technical process of knowledge circulation. It is a complex, dynamic, and systemic phenomenon subject to various variables that impede its progress in the country, such as: (a) institutional barriers; (b) a lack of investment in R&D&I; (c) organizational culture and business perception; (d) a lack of implementation of international strategies applicable to the context; (e) a limited scope of government policies that streamline these processes. It is important to note that all of the aforementioned factors are also influenced by institutional structures, territorial inequality, and cultural diversity.

The study posits that institutional barriers stem from a paucity of collaboration among stakeholders within the innovation system, attributable to organizational rigidity and an absence of technology transfer models that are adapted to the realities of the context. Moreover, the persistent underfunding of R&D&I in the country has been shown to impede the establishment of effective channels for technology transfer and investment in this domain, thereby hindering the adoption of novel technologies.

With regard to organizational culture, the results indicate that it plays a leading role in the adoption of technologies, which in turn drives technology transfer. This variable reveals a disconnection between the technologies offered by academia and the needs of businesses. This constitutes a challenge that must be addressed to strengthen ties and ensure that the business community sees universities as a source of technological solutions adapted to the context.

In addition, there are international success stories, as well as various strategies that could incorporate context and strengthen technology transfer: knowledge-based learning, inclusive technology adoption and adapted management models, as well as joint research initiatives, climate adaptation measures, real-time monitoring, transnational collaboration networks, evidence-based evaluation, and finally, hybrid technology transfer office (TTO) models and open innovation strategies.

It is therefore unsurprising that public policies are deemed to be of crucial importance for the strengthening of technology transfer in the country. In order to facilitate the streamlining of these processes, it is essential to establish comprehensive legislative frameworks that can support, encourage, and incentivize engagement between stakeholders. In emerging countries, these have been shown to be key factors in improving the innovation environment through inclusion policies, international financing, and bilateral cooperation, which will help reduce structural barriers and foster a more integrated innovation system.

In conclusion, it is evident that technology transfer in Colombia necessitates a comprehensive approach that simultaneously addresses institutional, economic, and cultural factors. It is imperative to strengthen existing public policies, increase investment in R&D, foster a culture of cooperation between academia and the business sector, and learn from successful international experiences to design strategies tailored to local needs. In order to achieve the optimization of technology transfer and, by extension, the economic development and competitiveness of the nation, it is essential that there is a greater degree of collaboration and alignment of interests among the key stakeholders.

The analysis demonstrates that, in order to comprehensively address the relationship between science, technology and society, it is imperative to undertake a systematic review of the conceptual frameworks that guide this relationship. National evidence indicates that imported, decontextualized, or linear models reproduce forms of exclusion when they ignore local trajectories, community dynamics, and ancestral knowledge.

Achieving effective transfer requires dialogue between diverse rationalities, ongoing adaptation processes, and recognition of the scales at which innovation is produced and appropriated. In order to move forward with this endeavor, it is essential to build trust among stakeholders, to understand the sociocultural environments in which they operate, and to strengthen institutional capacities. These conditions permit the transformation of conventional approaches and the generation of new forms of interaction.

A review of these dimensions has been shown to enhance academic comprehension of the phenomenon, thereby providing essential components for the formulation of inclusive and sustainable policies. The promotion of technology transfer with a territorial focus and social commitment is not merely an operational challenge. This decision is indicative of a conscientious approach to the nation's equitable development.

In response to the challenges affecting the success of technology transfer in Colombia, the study proposes six strategic lines of action aimed at strengthening and enhancing these processes across different levels and sectors. The first strategy emphasizes the importance of flexible policy formulation and capacity building, highlighting that public policies must be able to adapt to evolving circumstances and promote collaboration among stakeholders in the national innovation system. These policies should not remain confined to the national level but must also be deployed across regional and local governance structures. In particular, it is essential to support the creation, revitalization, and long-term sustainability of Technology Transfer Offices (OTRIs) by equipping them with the necessary resources, personnel, and tools to fulfill their central role in technology transfer and capacity building. Equally important is the simplification of administrative procedures between system actors, especially in formalizing agreements, establishing conventions, and facilitating the creation of academic spin-offs.

The second strategic line calls for the design of regional innovation policies tailored to the specific characteristics and needs of local productive sectors. These policies must address critical areas such as agricultural innovation, environmental sustainability, and climate change adaptation. Furthermore, it is crucial to strengthen international cooperation through research networks and collaborative projects, and to develop targeted support mechanisms for SMEs—considered the backbone of Colombia's productive system—through training, financing, and network integration, thus facilitating their entry into the national innovation ecosystem.

A third priority involves increasing investment in research, development, and innovation (R&D&I). While Colombia has some fiscal and financial incentives in place, their impact remains limited unless they are continuously promoted and refined. There is a clear need for the creation of more programs, projects, and policy instruments that stimulate innovation, along with mechanisms that foster public-private partnerships to support technology transfer, particularly in strategic sectors of the economy.

The fourth line of action underscores the necessity of building a culture of trust, collaboration, and cooperation among key stakeholders. Effective technology transfer depends on strong relationships between academia, industry, and other actors, and it is therefore essential to promote engagement activities that foster mutual trust and highlight successful case studies. Academic institutions play a central role here by developing initiatives that help other stakeholders recognize the value of technology transfer and its contributions to innovation.

The fifth strategy focuses on adapting international models for technology transfer to the Colombian context. While it is useful to study and implement practices from established Technology Transfer Offices abroad, these models must be adjusted to reflect local realities and leverage domestic knowledge to strengthen national strategic sectors. To do so, it is necessary to build meaningful relationships with international peers, networks, and programs that facilitate knowledge exchange and collaboration, ultimately enhancing Colombia's ability to integrate into the global innovation system.

Finally, the sixth strategic line addresses the imperative of aligning technology transfer with sustainability and climate change adaptation. Technological development cannot be detached from environmental and social concerns, particularly in rural and marginalized communities. The technologies promoted must address real community needs and prioritize sustainability goals, including efficient energy use, sustainable agriculture, and climate resilience. A key element is the incorporation of communal models that integrate ancestral, Afro-Colombian, indigenous, and local knowledge with new technologies, ensuring inclusive and context-sensitive innovation processes that promote both environmental stewardship and social equity.