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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Reprod. Health</journal-id>
<journal-title>Frontiers in Reproductive Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Reprod. Health</abbrev-journal-title>
<issn pub-type="epub">2673-3153</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/frph.2023.1105390</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Reproductive Health</subject>
<subj-group>
<subject>Systematic Review</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Effectiveness of interventions to reduce child marriage and teen pregnancy in sub-Saharan Africa: A systematic review of quantitative evidence</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes"><name><surname>Feyissa</surname><given-names>Garumma Tolu</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref><uri xlink:href="https://loop.frontiersin.org/people/789894/overview"/></contrib>
<contrib contrib-type="author"><name><surname>Tolu</surname><given-names>Lemi Belay</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref><uri xlink:href="https://loop.frontiersin.org/people/997007/overview" /></contrib>
<contrib contrib-type="author"><name><surname>Soboka</surname><given-names>Matiwos</given-names></name>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref><uri xlink:href="https://loop.frontiersin.org/people/1829441/overview" /></contrib>
<contrib contrib-type="author"><name><surname>Ezeh</surname><given-names>Alex</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib>
</contrib-group>
<aff id="aff1"><label><sup>1</sup></label><addr-line>Dornsife School of Public Health</addr-line>, <institution>Drexel University</institution>, <addr-line>Philadelphia</addr-line>, <country>PA, United States</country></aff>
<aff id="aff2"><label><sup>2</sup></label><institution>Department of Obstetrics and Gynecology, Saint Paul Hospital Millennium Medical College</institution>, <addr-line>Addis Ababa</addr-line>, <country>Ethiopia</country></aff>
<aff id="aff3"><label><sup>3</sup></label><addr-line>Department of Psychiatry</addr-line>, <institution>Jimma University</institution>, <addr-line>Jimma</addr-line>, <country>Ethiopia</country></aff>
<author-notes>
<fn fn-type="edited-by"><p><bold>Edited by:</bold> Nega Assefa, Haramaya University, Ethiopia</p></fn>
<fn fn-type="edited-by"><p><bold>Reviewed by:</bold> Eileen Ai-liang Yam, Mathematica, Inc., United States Sugarmaa Myagmarjav, Mongolian National University of Medical Sciences, Mongolia</p></fn>
<corresp id="cor1"><label>&#x002A;</label><bold>Correspondence:</bold> Garumma Tolu Feyissa <email>garummatolu@yahoo.com</email></corresp>
<fn fn-type="other" id="fn001"><p><bold>Specialty Section:</bold> This article was submitted to Adolescent Reproductive Health and Well-being, a section of the journal Frontiers in Reproductive Health</p></fn>
<fn fn-type="other" id="fn002"><p>Abbreviations AIDS, Acquired Immuno-deficiency Syndrome; AOR, Adjusted odds ratio; CT, Cash Transfer; CCT, Conditional cash transfer; CENTRAL, Cochrane Database of Systematic Reviews; CI, Confidence interval; CINAHL, Cumulative Index to Nursing and Allied Health Literature; cRTs, Cluster-randomized trials; FP, Family Planning; HEWC, Interventions consisting of health, education promotion, wealth building and community dialogue components; HIV, Human Immuno-deficiency Virus; HR, Hazard ratio; IEC, Information, education, and communication; JBI, Joanna Briggs Institute; OVC, Orphan and vulnerable children; PP, percentage point; PRISMA-ScR, Preferred Reporting Items for Systematic Reviews and Meta-Analyses for scoping reviews; RH, Reproductive Heath; RR, Relative risk; SBCC, Social and behavioral change communication; SRH, Sexual and Reproductive Heath; SSA, Sub-Saharan Africa; TFR, Total Fertility Rate; TT, Teachers&#x0027; training; UCCT, Unconditional cash transfer; UNICEF, United Nations Children&#x0027;s Fund; VE, Violence prevention combined with and education promotion; VEH, Violence, Education and Health; VEHW, Violence prevention, education promotion, health, and wealth creation; WHO, World Health Organization; YFS, Youth Friendly Services.</p></fn>
</author-notes>
<pub-date pub-type="epub"><day>31</day><month>03</month><year>2023</year></pub-date>
<pub-date pub-type="collection"><year>2023</year></pub-date>
<volume>5</volume><elocation-id>1105390</elocation-id>
<history>
<date date-type="received"><day>22</day><month>11</month><year>2022</year></date>
<date date-type="accepted"><day>03</day><month>03</month><year>2023</year></date>
</history>
<permissions>
<copyright-statement>&#x00A9; 2023 Feyissa, Tolu, Soboka and Ezeh.</copyright-statement>
<copyright-year>2023</copyright-year><copyright-holder>Feyissa, Tolu, Soboka and Ezeh</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<abstract>
<sec><title>Introduction</title>
<p>Child marriage and teen pregnancy have negative health, social and development consequences. Highest rates of child marriage occur in sub-Saharan Africa (SSA) and 40&#x0025; of women in Western and Central Africa got married before the age of 18. This systematic review was aimed to fill a gap in evidence of effectiveness to reduce teen pregnancy and child marriage in SSA.</p>
</sec>
<sec><title>Methods</title>
<p>We considered studies conducted in sub-Saharan Africa that reported on the effect of interventions on child marriage and teen pregnancy among adolescent girls for inclusion. We searched major databses and grey literature sources.</p>
</sec>
<sec><title>Results</title>
<p>We included 30 articles in this review. We categorized the interventions reported in the review into five general categories: (a) Interventions aimed to build educational assets, (b) Interventions aimed to build life skills and health assets, (c) Wealth building interventions, and (d) Community dialogue. Only few interventions were consistently effective across the studies included in the review. The provision of scholarship and systematically implemented community dialogues are consistently effective across settings.</p>
</sec>
<sec><title>Conclusion</title>
<p>Program designers aiming to empower adolescent girls should address environmental factors, including financial barriers and community norms. Future researchers should consider designing rigorous effectiveness and cost effectiveness studies to ensure sustainability.</p>
</sec>
<sec><title>Systematic Review Registration</title>
<p><ext-link ext-link-type="uri" xlink:href="https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=327397">https://www.crd.york.ac.uk/prospero/</ext-link>, identifier: CRD42022327397.</p>
</sec>
</abstract>
<kwd-group>
<kwd>teen pregnancy</kwd>
<kwd>early marriage</kwd>
<kwd>systematic review</kwd>
<kwd>sub-Saharan Africa (SSA)</kwd>
<kwd>interventions</kwd>
</kwd-group>
<counts>
<fig-count count="1"/>
<table-count count="6"/><equation-count count="0"/><ref-count count="63"/><page-count count="0"/><word-count count="0"/></counts>
</article-meta>
</front>
<body>
<sec id="s1" sec-type="intro"><title>Introduction</title>
<p>The global population is projected to reach 9.71 and 10.35 billion by 2050 and 2100, respectively. Africa will account for 105&#x0025; of the projected total increase in global population between 2022 and 2100. Its population will increase from 1.36 billion in 2020 to 3.92 billion by 2100. This rapid growth, over a relatively short period, together with the compositional effects it will engender, will have significant implications for development prospects in the region (<xref ref-type="bibr" rid="B1">1</xref>). Recognizing this reality, African Heads of State and Government devoted the year 2017 to &#x201C;Harnessing the Demographic Dividend through Investments in Youth&#x201D; (<xref ref-type="bibr" rid="B2">2</xref>), as a critical pathway to realizing the continent&#x0027;s aspiration for economic transformation. Yet, concrete action in realizing this strong political moment has remained muted. Ninety-one percent (91&#x0025;) of this projected growth in Africa&#x0027;s population will be in sub-Saharan Africa (SSA).</p>
<p>The population growth of SSA is driven largely by high fertility and child onset of childbearing (<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B4">4</xref>). Apart from having more children on average than women in other regions, women in SSA generally start childbearing earlier and have very high levels of adolescent childbearing, high desired family size, and low levels of use of modern contraceptives (<xref ref-type="bibr" rid="B3">3</xref>&#x2013;<xref ref-type="bibr" rid="B5">5</xref>). Highest rates of child marriage occur in sub-Saharan Africa and as high as 40&#x0025; of women Western and Central Africa got married before the age of 18 (<xref ref-type="bibr" rid="B6">6</xref>).</p>
<p>Child marriage is the consequences of factors at such as low level of literacy of the girls and her parents, economic problems, gender norms and gender-based violence. Child marriage is one of the indicators of gender inequality and is an impediment against the full participation of girls in education and labor force (<xref ref-type="bibr" rid="B7">7</xref>). Child marriage and teen pregnancy remain obstacles against completion of secondary education and beyond. On the other hand, female education is a key predictor of fertility, especially secondary education and higher (<xref ref-type="bibr" rid="B8">8</xref>). Secondary and higher education may increase women&#x0027;s opportunities for work outside the home, their ability to contribute to decision making with their partners, and greater agency in taking action that advances their personal well-being and managing their family size (<xref ref-type="bibr" rid="B8">8</xref>&#x2013;<xref ref-type="bibr" rid="B10">10</xref>). It is also beneficial in tackling the negative economic impacts of child marriage (<xref ref-type="bibr" rid="B11">11</xref>) and contributes to the achievement of the sustainable development goals (SDG 5) (<xref ref-type="bibr" rid="B12">12</xref>). More importantly, better educated women are more likely to prioritize the education of their children thereby creating inter-generational benefits (<xref ref-type="bibr" rid="B8">8</xref>).</p>
<p>Early marriage is often associated with increased risk of teen pregnancy. Teen pregnancy also increases the risk of deadly health consequences such as eclampsia, puerperal endometritis, low birth weight, preterm birth, and other complications (<xref ref-type="bibr" rid="B13">13</xref>). The World Health Organization recommends that marriage before the age 18 and pregnancy before the age of 20 should be reduced (<xref ref-type="bibr" rid="B14">14</xref>).</p>
<p>Targeting adolescent girls with programs that reduce the onset of pregnancies will achieve multiple development outcomes and contribute significantly to reducing fertility and population growth rate&#x2014;in addition to its value to the girls, their families, communities, and society. First, there is a strong positive association between female education and onset of marriage and childbearing, fertility levels, fertility desires, independent fertility decisions (including use of contraception), and access to employment opportunities outside the home. More importantly, starting childbearing later increases the age gap between mothers and their daughters (intergenerational gap), which is seen as the second most important determinant of population growth, after fertility (number of children) (<xref ref-type="bibr" rid="B15">15</xref>).</p>
<p>Although there is emerging evidence from low- and middle-income countries that programs targeting adolescent girls with long-term follow up are likely to be effective and sustainable, there is limited evidence on what specific interventions or which aspects of complex intervention designs are effective in reducing child marriage and teen pregnancy (<xref ref-type="bibr" rid="B16">16</xref>).</p>
<p>Implementing evidence-based interventions that reduce teen pregnancies and child marriage is critical not only for the future development of the society, but also for the entire life and wellbeing of adolescents. It is, therefore, essential to synthesize the available evidence to guide future research and intervention focus. Our preliminary search found no recent systematic review that reported the effectiveness of interventions on teen pregnancy and child marriage in sub-Saharan Africa. Cognizant of this, this systematic review was aimed to identify and synthesize evidence on the effect of interventions that have been implemented to reduce teen pregnancy, and child marriage in sub-Saharan Africa.</p>
<sec id="s1a"><title>Research questions</title>
<p>The research questions addressed in this review were:
<list>
<list-item><label>1.</label><p>What is the best available evidence on the effectiveness of interventions seeking to reduce teen pregnancy among adolescent girls?</p></list-item>
<list-item><label>2.</label><p>What is the best available evidence on the effectiveness of interventions seeking to reduce child marriage among adolescent girls?</p></list-item>
</list></p>
</sec>
</sec>
<sec id="s2" sec-type="methods"><title>Methods</title>
<p>This systematic review was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) (<xref ref-type="bibr" rid="B17">17</xref>). We conducted the review based on an a-priori protocol (Registry number CRD42022327397) (<xref ref-type="bibr" rid="B18">18</xref>).</p>
<sec id="s2a"><title>Search strategy</title>
<p>We searched the following databases: PubMed, EMBASE, CINAHL, Web of Science, Science Direct, Cochrane Database of Systematic Reviews (CENTRAL), 3ie database. Sources of unpublished studies and gray literature include Google, ProQuest Dissertation and Theses, and Google Scholar. The search was conducted in three phases with the aim of locating both published and unpublished studies. An initial limited search of PubMed and CINAHL was conducted. The text words contained in the titles and abstracts of relevant articles, and the index terms used to describe the articles were used to develop a full search strategy for the relevant databases (<xref ref-type="sec" rid="s14">Supplementary file S1</xref>).</p>
</sec>
<sec id="s2b"><title>Eligibility criteria</title>
<p>During the conduct of the review, we considered the following inclusion criteria.</p>
<sec id="s2b1"><title>Population</title>
<p>This review considered studies that targeted or measured the effect of interventions on outcomes of adolescent girls and female young adults.</p>
</sec>
<sec id="s2b2"><title>Interventions</title>
<p>This review considered studies that reported on interventions designed to reduce child marriage, and/ or teen pregnancy.</p>
</sec>
<sec id="s2b3"><title>Comparator(s)</title>
<p>We considered comparisons of interest that included, but not limited to, any default program, standard of care, no intervention or any other alternative intervention compared to the main intervention.</p>
</sec>
<sec id="s2b4"><title>Outcomes</title>
<p>This review focused on the following outcomes: child marriage (marriage before 18 years), and teen pregnancy. For this review, to match with the definition adopted by the United Nations Child Fund (UNICEF), we defined child marriage as a marriage before the age of 18 years (<xref ref-type="bibr" rid="B19">19</xref>).</p>
</sec>
<sec id="s2b5"><title>Context</title>
<p>Studies conducted at any levels (individual, group, organizational, policy and community levels) or in schools in urban, rural, and pastoral settings of sub-Saharan Africa were considered for inclusion.</p>
</sec>
<sec id="s2b6"><title>Types of studies</title>
<p>We considered quantitative comparative studies having treatment and control groups published/reported in the English language and available online on or before January 26, 2022 (last search date) for inclusion. These include randomized controlled trials (both individual and cluster randomized trials), quasi-experimental studies having control groups. There was no further restriction on publication dates. Studies that did not have comparison group were not included in the review.</p>
</sec>
<sec id="s2b7"><title>Study selection</title>
<p>Following the search, all identified citations were collated using EndNote (<xref ref-type="bibr" rid="B20">20</xref>) and duplicates were removed. Titles and abstracts were then screened for assessment against the inclusion criteria for the review by two reviewers. The full text of selected citations was assessed in detail against the inclusion criteria.</p>
</sec>
<sec id="s2b8"><title>Methodological assessment</title>
<p>Two reviewers assessed the methodological qualities of the papers using the Joanna Briggs Institute (JBI) appraisal tools (<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B22">22</xref>). A third reviewer was invited where appropriate to settle disputes between primary and secondary reviewers.</p>
</sec>
<sec id="s2b9"><title>Data extraction and synthesis</title>
<p>We extracted data from studies included in the review using priori developed extraction form containing study ID, country of origin, study design, context, study population, outcomes reported and results. In the case of incomplete information reported in the articles, we contacted the authors of primary studies. In addition, we have taken further information from multiple versions of reports for the same intervention (such as the grey report versions, project report versions and other versions published in peer reviewed journals).</p>
<p>Because of clinical and methodological heterogeneity and the lack of consistency in the reporting of outcomes across different studies, and because of variation in intensity, content and duration of the interventions, it was not feasible to conduct meta-analysis. Therefore, we reported the findings in narrative form. Where possible, we reported findings on subgroups separately for out of school adolescents, in-school adolescents, and based on age category.</p>
</sec>
</sec>
</sec>
<sec id="s3"><title>Findings of the review</title>
<p>Initial search yielded 1,664 articles. After removing duplicates 1,323 articles were left for screening by title and abstract, out of which 317 articles were left for full text reading. Finally, 30 articles were included. Detailed information was sought from the articles having different versions of the reports. Some of these studies had long report versions and short published versions published in peer reviewed journal articles. Even though information from the seven redundant articles was included to enrich the original studies, these redundant articles were not counted as separate studies. Hence, the records were considered as 30 articles (<xref ref-type="fig" rid="F1">Figure&#x00A0;1</xref>). On the other hand, reports from the same trial were treated separately if they reported on different outcomes or if they addressed different data points.</p>
<fig id="F1" position="float"><label>Figure 1</label>
<caption><p>Study selection process.</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="frph-05-1105390-g001.tif"/>
</fig>
<p>The studies whose reports were merged include Baird 2009 (<xref ref-type="bibr" rid="B23">23</xref>), Baird 2010 (<xref ref-type="bibr" rid="B24">24</xref>) and Baird 2011 (<xref ref-type="bibr" rid="B25">25</xref>); Baird 2015 (<xref ref-type="bibr" rid="B26">26</xref>) and Baird 2016 (<xref ref-type="bibr" rid="B27">27</xref>); Duflo 2014 (<xref ref-type="bibr" rid="B28">28</xref>) and Duflo 2015 (<xref ref-type="bibr" rid="B29">29</xref>), Bandiera 2012 (<xref ref-type="bibr" rid="B30">30</xref>), Bandiera 2015 (<xref ref-type="bibr" rid="B31">31</xref>), Bandiera 2017 (<xref ref-type="bibr" rid="B32">32</xref>), Bandiera 2018 (<xref ref-type="bibr" rid="B33">33</xref>) and Bandiera 2020 (<xref ref-type="bibr" rid="B34">34</xref>); Dupas 2009 (<xref ref-type="bibr" rid="B35">35</xref>) and Dupas 2011 (<xref ref-type="bibr" rid="B36">36</xref>). On the other hand, four studies conducted in Zimbabwe (<xref ref-type="bibr" rid="B37">37</xref>, <xref ref-type="bibr" rid="B38">38</xref>)) and Ghana (<xref ref-type="bibr" rid="B39">39</xref>, <xref ref-type="bibr" rid="B40">40</xref>) that reported data at different time points from the same trial were reported separately.</p>
<sec id="s3a"><title>Description of the studies</title>
<p>Out of the 30 articles, 19 of them reported on child marriage and 22 of them on teen pregnancy, 12 of them reported on both teen pregnancy and child marriage.</p>
<p>Twenty-seven (27) of the studies were cluster randomized trials, three individual randomized trials (<xref ref-type="bibr" rid="B39">39</xref>, <xref ref-type="bibr" rid="B41">41</xref>, <xref ref-type="bibr" rid="B42">42</xref>), and three quasi-experimental studies (<xref ref-type="bibr" rid="B43">43</xref>&#x2013;<xref ref-type="bibr" rid="B45">45</xref>). The articles covered projects conducted in nine Sub-Saharan African countries, including Zambia, Zimbabwe, Malawi, Kenya, Ghana, Uganda, Tanzania, Ethiopia, and Burkina Faso (<xref ref-type="table" rid="T1">Table&#x00A0;1</xref>).</p>
<table-wrap id="T1" position="float"><label>Table 1</label>
<caption><p>Characteristics of included studies</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">No.</th>
<th valign="top" align="center">Study</th>
<th valign="top" align="center">Country</th>
<th valign="top" align="center">Design</th>
<th valign="top" align="center">Context</th>
<th valign="top" align="center">Participants</th>
<th valign="top" align="center">Interventions arms</th>
<th valign="top" align="center">Results</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">1.</td>
<td valign="top" align="left">Chow 2021</td>
<td valign="top" align="left">Ethiopia</td>
<td valign="top" align="left">Quasi-experiment</td>
<td valign="top" align="left">School and community</td>
<td valign="top" align="left">Girls aged 8&#x2013;17 years (901control and 1952 intervention)</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Expansion (Community dialogue and information provision)<break/><bold>Arm 2:</bold> Extensive (Community dialogue and information and economic incentive)</td>
<td valign="top" align="left"><bold>Marriage:</bold> Both interventions decreased the probability that a girl aged 8&#x2013;17 had ever been married by 4 to 7pps. The intensive arm reduced child marriage by 2&#x2013;3pps more than the expansion treatment (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left"><bold>2.</bold></td>
<td valign="top" align="left">Waidler 2022</td>
<td valign="top" align="left">Tanzania</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">Community</td>
<td valign="top" align="left">2,191 (1,128 control and 1,063 intervention) youth from 1,779 households</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Cash (CCT and UCCT) Plus livelihoods and life skills training, and an asset transfer, with linkages to HIV and SRH services. The CCT was conditioned upon school enrolment and seeking health)<break/><bold>Arm 2:</bold> Cash-only</td>
<td valign="top" align="left"><bold>Marriage:</bold> The intervention reduced probability of getting married among adolescent girls (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05)<break/><bold>Pregnancy</bold><break/>No significant effect on teen pregnancy(<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05)</td>
</tr>
<tr>
<td valign="top" align="left">3.</td>
<td valign="top" align="left">Austrian 2022</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">Urban slum community</td>
<td valign="top" align="left">2,147 girls aged 11&#x2013;14 years in 2015 until 2019</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Community dialogue for violence prevention (V)<break/><bold>Arm 2:</bold> Violence prevention and Education promotion <italic>via</italic> conditional cash transfer, (VE)<break/><bold>Arm 3:</bold> Violence prevention, education promotion, and health and life skills training (health) (VEH)<break/><bold>Arm 4:</bold> Community dialogue for violence prevention, Education, Health, and financial literacy training (wealth creation) (VEHW)</td>
<td valign="top" align="left"><bold>Marriage:</bold><break/>In the adjusted analysis, VEHW arm reduced child marriage among baseline out-of-schoolgirls, but not in the full sample (compared to V only arm) (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05). Both among full sample and among out-of-school girls, VE resulted in higher reduction in risk of marriage compared to V only (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05). No significant effect in other arms.<break/><bold>Pregnancy</bold><break/>Compared to V alone, the effects of VE on pregnancy were large and significant for girls not in school at baseline (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05). The effect was not significant among full sample. No significant effect on pregnancy in other arms.<break/><bold>Marriage and pregnancy</bold><break/>The pooled study arm (combination of all the three arms together (VE, VEH and VEHW) reduced marriage by 18 pp and pregnancy by 15.6pp a relative reduction of 34&#x0025; and 43&#x0025;, respectively (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">4.</td>
<td valign="top" align="left">Kengwann 2022</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left">RCT</td>
<td valign="top" align="left">Pastoral</td>
<td valign="top" align="left">2,075 girls 11&#x2013;14 years old in 2015 until 2019</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Community dialogue about inequitable gender norms and violence prevention (V)<break/><bold>Arm 2:</bold> Violence prevention and education promotion <italic>via</italic> conditional cash transfer, (VE),<break/><bold>Arm 3:</bold> VEH, Violence, Education promotion, and weekly group meetings with health and life skills training (Health)<break/><bold>Arm 4:</bold> Violence, Education promotion, Health, and financial literacy training (Wealth creation) (VEHW)</td>
<td valign="top" align="left"><bold>Pregnancy</bold><break/>No statistically significant effect of HEW, VE, VEH vs. V only both for the full sample and for those aged 13&#x2013;14 years at baseline on teen pregnancy (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">5.</td>
<td valign="top" align="left">Erulkar 2020</td>
<td valign="top" align="left">Burkina Faso and Tanz&#x00E2;nia</td>
<td valign="top" align="left">Quasi experimental</td>
<td valign="top" align="left">Rural schools and community</td>
<td valign="top" align="left">2,500 girls aged<break/>12&#x2013;17 years in each country</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Community dialogue<break/><bold>Arm 2:</bold> School supplies, <bold>Arm 3:</bold> Conditional livestock asset transfer conditioned on the 12&#x2013;17-year-old girls remaining unmarried and in school for the duration of the pilot period (27&#x2013;28 months)<break/><bold>Arm 4:</bold> Combined (Community dialogue, school supplies, and conditional asset transfer)<break/><bold>Arm 5:</bold> Control</td>
<td valign="top" align="left"><bold>Marriage</bold><break/><bold>Burkina Faso:</bold> Among those in the community dialogue arm, girls aged 15&#x2013;17 had two-thirds less risk RR&#x2009;&#x003D;&#x2009;0.33; 95&#x0025; CI, 0.19, 0.60) of being married compared to the control site.<break/><bold>Tanzania:</bold> Girls aged 12&#x2013;14 in the multicomponent arm had two-thirds less risk of being married (RR&#x2009;&#x003D;&#x2009;0.33; 95&#x0025; CI&#x2009;&#x003D;&#x2009;0.11, 0.99), and girls 15 to 17 in the conditional asset location had half the risk (RR&#x2009;&#x003D;&#x2009;0.52; 95&#x0025; CI&#x2009;&#x003D;&#x2009;0.30, 0.91).</td>
</tr>
<tr>
<td valign="top" align="left">6.</td>
<td valign="top" align="left">Erulkar 2009</td>
<td valign="top" align="left">Ethiopia</td>
<td valign="top" align="left">Quasi</td>
<td valign="top" align="left">School</td>
<td valign="top" align="left">Adolescent girls aged 10&#x2013;19 (188 intervention and 272 girls in control)</td>
<td valign="top" align="left"><bold>Arm 1: Intervention</bold><break/>a) Community conversations(b) School supplies (c) Conditional<break/>asset transfer, promising girls, and their families a goat if they remain unmarried and in school<break/>(d) Girls&#x2019; groups led by adult women mentors<break/><bold>Arm 2:</bold> control</td>
<td valign="top" align="left"><bold>Marriage</bold><break/>At end line, girls aged 10&#x2013;14 in the intervention arm were 1/10th as likely to have gotten married compared to girls at the control site (0.1). Girls aged 15&#x2013;19 in the intervention arm had 2.4 times elevated risk of getting married (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.01)</td>
</tr>
<tr>
<td valign="top" align="left">7.</td>
<td valign="top" align="left">Handa 2015</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">Community</td>
<td valign="top" align="left">1,549 females aged 12 to 24</td>
<td valign="top" align="left"><bold>Arm 1: Intervention</bold><break/>Cash Transfer (UCCT) for OVC<break/><bold>Arm 2:</bold> Control</td>
<td valign="top" align="left"><bold>Marriage:</bold> At 4 years-follow up UCCT reduced likelihood of pregnancy by 5.5 pp (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05) relative to control arm, no impact on child marriage (reduction by 20&#x0025;) (<italic>p</italic>&#x2009;&#x003D;&#x2009;0.21).</td>
</tr>
<tr>
<td valign="top" align="left">8.</td>
<td valign="top" align="left">UNC 2016</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">Household</td>
<td valign="top" align="left">2,109 Youth 13&#x2013;19</td>
<td valign="top" align="left"><bold>Arm 1: Intervention</bold><break/>Cash transfer (UCCT) to ultra-poor rural households<break/><bold>Arm 2:</bold> Control</td>
<td valign="top" align="left"><bold>Pregnancy:</bold> After 2 years, among the 13&#x2013;19-year-olds at baseline, 20&#x0025; of female youth in intervention arm and 24&#x0025; of female youth in control arm had experienced pregnancy(<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).<break/><bold>Marriage:</bold> 7&#x0025; of the intervention sample and 8&#x0025; of the control arm reported being married (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">9.</td>
<td valign="top" align="left">Dake 2018</td>
<td valign="top" align="left">Malawi and Zambia</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">Rural household</td>
<td valign="top" align="left">Youth aged 14 to 21 years (1,023 in Malawi and 1,070 in Zambia</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Intervention Cash transfer (UCCT) to ultra-poor rural households<break/><bold>Arm 2:</bold> Control</td>
<td valign="top" align="left"><bold>Malawi</bold><break/><bold>Marriage:</bold> Cash transfer programs had no impact on ever married (b&#x2009;&#x003D;&#x2009;&#x2212;0.00428) (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).<break/><bold>Pregnancy:</bold> No impact on ever pregnant (0.00507) (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).<break/><bold>Zambia</bold><break/><bold>Marriage:</bold> No impact on ever married (b&#x2009;&#x003D;&#x2009;0.0117) (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).<break/><bold>Pregnancy:</bold> No impact on ever pregnant (0.000716) (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">10.</td>
<td valign="top" align="left">Baird 2016</td>
<td valign="top" align="left" rowspan="2">Malawi</td>
<td valign="top" align="left" rowspan="2">CRT<break/><break/></td>
<td valign="top" align="left" rowspan="2">In school and out of school</td>
<td valign="top" align="left" rowspan="2">Never married young women aged 13 to 22 years old</td>
<td valign="top" align="left" rowspan="2"><bold>Arm 1:</bold><break/>Conditional Cash transfer (CCT) (based on school attendance), to families of school aged girls and school fee waives<break/><bold>Arm 2:</bold> Unconditional cash transfer (UCCT)<break/><bold>Arm 3:</bold> Control</td>
<td valign="top" align="left"><bold>A.Marriage</bold><break/><bold>Marriage (baseline dropouts</bold>)<break/>Baseline dropouts who were in CCT arm were 14.0, 15.7, and 10.7 pp less likely to have been ever married at one-, two-, and five-year follow-ups, respectively (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.01).<break/><bold>Marriage (baseline schoolgirls CCT):</bold><break/>No effects on teen child marriage for the CCT arm among baseline schoolgirls at round 4 (as in earlier rounds).<break/><bold>Marriage (baseline schoolgirls UCCT):</bold> UCCT was effective on baseline schoolgirls during and immediately upon completion, but UCCT did not have any impact on ever married on baseline schoolgirls at (round 4) five-year follow up (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).<break/><bold>B.Pregnancy</bold><break/><bold>Pregnancy (baseline dropouts):</bold> Baseline dropouts who were in CCT arm were 5.7, 8.1, and 3.8 pp less likely to have ever been pregnant (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.10).<break/><bold>Pregnancy (baseline schoolgirls CCT):</bold> No effects on teen pregnancy for the CCT arm among baseline schoolgirls at round 4 (as in earlier rounds) (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).<break/><bold>Baseline schoolgirls UCCT:</bold> UCCT was effective on baseline schoolgirls during and immediately upon completion, but UCCT did not have any impact on ever pregnant on baseline schoolgirls at (round 4) five-year follow up (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">11.</td>
<td valign="top" align="left">Baird 2009</td>
<td valign="top" align="left"><bold>Marriage</bold><break/><bold>During the program</bold>:<break/>4.3&#x0025; were married in the control group. Marriage rates were unchanged in the CCT arm but significantly lower in the UCT arm.<break/><bold>Immediately after the program ended):</bold> The prevalence of marriage rose to 18.0&#x0025; in the control arm with an insignificant reduction of 1.2 pp in the CCT arm and a significant reduction of 7.9 pp (44&#x0025;) in the UCT arm. The likelihood of ever being pregnant was reduced by 6.7pp (27&#x0025;) in the UCT arm (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.01)</td>
</tr>
<tr>
<td valign="top" align="left">12.</td>
<td valign="top" align="left">Bandiera 2015</td>
<td valign="top" align="left" rowspan="3">Uganda</td>
<td valign="top" align="left" rowspan="3">CRT</td>
<td valign="top" align="left" rowspan="3">Clubs in fixed meeting places in communities (Rural and urban)</td>
<td valign="top" align="left" rowspan="3">5,966 Girls aged 14&#x2013;20 (3,964 in treatment 2,002 in control)</td>
<td valign="top" align="left" rowspan="3"><bold>Arm 1:</bold> Intervention (Empowerment and livelihood program for adolescents implemented <italic>via</italic> adolescent development clubs, female mentor (life skills training to run small-scale enterprises, and vocational skills training, information on sex, reproduction, and marriage<break/><bold>Arm 2:</bold> Control</td>
<td valign="top" align="left" rowspan="2"><bold>Marriage:</bold> Two years after intervention, girls in intervention arm were 6.9 pp less likely to be married, corresponding to 53&#x0025; of the baseline mean. In control arm, marriage rates rose naturally from 12&#x0025; to 18&#x0025; from baseline to follow-up (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05).<break/><bold>Pregnancy:</bold> Teen pregnancy fell by 26&#x0025; in the intervention arm (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">13.</td>
<td valign="top" align="left" rowspan="2">Bandiera 2020</td>
</tr>
<tr>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>Marriage:</bold> At endline (four years after intervention) participants are 8pp less likely to be married. Marriage fell by 62&#x0025; (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05).<break/><bold>Pregnancy: T</bold>he probability of teen pregnancy was 3.8pp lower than control (corresponding to 34&#x0025; of baseline rate of pregnancy) (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05)</td>
</tr>
<tr>
<td valign="top" align="left">14.</td>
<td valign="top" align="left">Hedgayhl 2021</td>
<td valign="top" align="left">Zambia</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">School</td>
<td valign="top" align="left">4,922 Girls from grade 7 in 157 selected schools</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Economic support alone (cash transfers to girls and their parents and payment of school fees for girls continuing to secondary school)<break/><bold>Arm 2:</bold> Economic support in combination with a community dialogue (community and youth meetings to enhance sexual and reproductive health knowledge and supportive community norm)<break/><bold>Arm 3:</bold> Control</td>
<td valign="top" align="left"><bold>Marriage:</bold> Compared to control, incidence of marriage before age 18 was 21&#x0025; and 14&#x0025; lower in the combined and economic arms, respectively CI&#x2009;&#x003D;&#x2009; (combined vs. control HR 0.79, 95&#x0025; CI, 0.61&#x2013;1.04; economic vs. control HR 0.86, 95&#x0025; CI, 0.65&#x2013;1.13)</td>
</tr>
<tr>
<td valign="top" align="left">15.</td>
<td valign="top" align="left">Sinsamala 2021</td>
<td valign="top" align="left">Zambia</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">Rural primary (Grade 1&#x2013;7) and junior secondary (Grade 8&#x2013;9) schools</td>
<td valign="top" align="left">4,922 girls</td>
<td valign="top" align="left"><bold>Arm1:</bold> Combined Economic support to parents, girls, and community intervention<break/><bold>Arm 2:</bold> Economic support only.<break/><bold>Arm 3:</bold> Control</td>
<td valign="top" align="left"><bold>Pregnancy:</bold> The difference in pregnancy incidence between the combined intervention and control arm was 17&#x0025; (HR 0.83 (95&#x0025; CI, 0.68&#x2013;1.00) and between economic support and control was 16&#x0025; (HR 0.84 (95&#x0025; CI, 0.69&#x2013;1.02). There was no difference between the combined intervention and economic support on pregnancy incidence (HR 0.99 (95&#x0025; CI, 0.83&#x2013;1.17).</td>
</tr>
<tr>
<td valign="top" align="left">16.</td>
<td valign="top" align="left">Austrian 2020</td>
<td valign="top" align="left">Zambia</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">Community</td>
<td valign="top" align="left">4,661 unmarried girls aged 10&#x2013;19 years</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Safe spaces only<break/><bold>Arm 2:</bold> Safe spaces plus health voucher<break/><bold>Arm 3:</bold> Safe spaces, health voucher, financial education and saving account<break/><bold>Arm 4:</bold> Control</td>
<td valign="top" align="left"><bold>Pregnancy:</bold> No positive program impacts, neither at the end of the intervention, nor two years after the end of the intervention, for ever been pregnant.<break/><bold>Marriage</bold>: No positive program impacts, neither at the end of the intervention nor two years after the end of the intervention.</td>
</tr>
<tr>
<td valign="top" align="left">17.</td>
<td valign="top" align="left">Hallfors 2015</td>
<td valign="top" align="left" rowspan="2">Zimbabwe</td>
<td valign="top" align="left" rowspan="2">CRT</td>
<td valign="top" align="left" rowspan="2">25 rural primary schools</td>
<td valign="top" align="left" rowspan="2">328 orphan adolescent girls in grade 6</td>
<td valign="top" align="left" rowspan="2"><bold>Arm 1:</bold> School subsidies (fees, uniforms, supplies and a school-based female helper to monitor attendance)<break/><bold>Arm 2:</bold> Delayed intervention</td>
<td valign="top" align="left"><bold>Marriage:</bold> Fewer girls among the intervention arm reported marriage [18 (11.2&#x0025;)] vs. [29 (23.6&#x0025;)] OR&#x2009;&#x003D;&#x2009;0.37 (95&#x0025;CI, 0.16&#x2013;0.88) (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05).<break/><bold>Pregnancy:</bold> Fewer girls among the intervention arm reported pregnancy [19 (11.8&#x0025;) vs. [28 (22.2&#x0025;)] compared to the delayed partial intervention arm after 5 years (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">18.</td>
<td valign="top" align="left">Hallfors 2011</td>
<td valign="top" align="left"><bold>Marriage:</bold> After two years, the control arm was much more likely to marry (OR&#x2009;&#x003D;&#x2009;2.9; CI&#x2009;&#x003D;&#x2009;1.0&#x2013;8.3) compared to the intervention arm.</td>
</tr>
<tr>
<td valign="top" align="left">19.</td>
<td valign="top" align="left">Duflo 2010</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">School</td>
<td valign="top" align="left">18,000 students</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Teachers&#x2019; training (TT) on HIV curriculum<break/><bold>Arm 2:</bold> Free school uniforms</td>
<td valign="top" align="left"><bold>Marriage:</bold> 2.5 years after baseline, girls who received uniforms were 1.7 pp less (14&#x0025;) likely to be married. Both TT and the combined (uniform and TT) did not have significant difference from control (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).<break/><bold>Pregnancy:</bold> 2.5 years after baseline, girls who received uniforms were 1.5pp less (10&#x0025;) less likely to be pregnant. Both TT and the combined (uniform and TT) did not have significant difference from control (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">20.</td>
<td valign="top" align="left">Duflo 2006</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">School</td>
<td valign="top" align="left">70,000 students from 328 primary schools</td>
<td valign="top" align="left">&#x00A0;<bold>Arm 1:</bold> Teachers&#x2019; training (TT) on HIV/AIDS curriculum <bold>Arm 2:</bold> Debate and write essay on role of condoms<break/><bold>Arm 3:</bold> Informing about risk of HIV<break/><bold>Arm 4:</bold> Reducing cost of education by providing free uniforms</td>
<td valign="top" align="left"><bold>Marriage:</bold> Girls in schools where free uniforms were provided were 1.4 pp (12&#x0025;) less likely to be married (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05). No effect of TT.<break/><bold>Pregnancy:</bold> A year after the intervention, girls who had received information on the profile of HIV infections by age and gender were 65&#x0025; less likely to have gotten pregnant by adult partners (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05). Overall, childbearing rates fell by 32&#x0025; among girls who were exposed to the information on relative risks. No effect of TT.</td>
</tr>
<tr>
<td valign="top" align="left">21.</td>
<td valign="top" align="left">Duflo 2015</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">328 schools in Kenya&#x0027;s Western Province</td>
<td valign="top" align="left">19,000 students enrolled in grade 6 in 2,003</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Educational subsidies<break/><bold>Arm 2:</bold> HIV education and information (abstinence until marriage)<break/><bold>Arm 3:</bold> Educational subsidy plus HIV education<break/><bold>Arm 4:</bold> Add on HIV education, educational subsidy plus information on condom</td>
<td valign="top" align="left"><bold>Pregnancy:</bold> After 3 years, education subsidies reduced adolescent girls&#x2019; pregnancy (from 16&#x0025; to 13&#x0025;). By year 7, there was still a 7&#x0025; gap in the childbearing rate between girls exposed to the education subsidy program and those in the control group (46&#x0025; vs. 49&#x0025;). Arm 2 did not significantly reduce teenage pregnancy. When the two programs were implemented jointly, teen pregnancy fell less than when the education subsidy was provided alone (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">22.</td>
<td valign="top" align="left">Dupas 2011</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">328 primary schools in rural districts</td>
<td valign="top" align="left">13,000 youths</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Teacher training (TT) on national policy on HIV/AIDS curriculum (abstinence-only (163 schools),<break/><bold>Arm 2:</bold> Relative risk (RR) Communication (provision of info for Grade 8 students in 71 schools on HIV prevalence by sex and age)</td>
<td valign="top" align="left"><bold>Pregnancy:</bold> The RR reduced risk of pregnancy by 27.7&#x0025; The RR program averts 29.4 pregnancies by older partners. The incidence of cross generational pregnancies declined by 61.7&#x0025; in the RR arm relative to the comparison arm (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05). The national abstinence-only HIV education curriculum had no impact on teen pregnancy (11.1&#x0025; reduction only) (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">23.</td>
<td valign="top" align="left">Dupas 2006</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">328 primary schools in rural districts</td>
<td valign="top" align="left">13,000 youths</td>
<td valign="top" align="left"><bold>Arm1:</bold> Relative risk information on the prevalence of HIV<break/>disaggregated by age and gender<break/><bold>Arm 2:</bold> Teachers training on school-based HIV curriculum (Control)</td>
<td valign="top" align="left">The RR reduced teen pregnancy by 31.4&#x0025;. There was 65&#x0025; reduction in the incidence of pregnancies by adult partners relative to the control arm <italic>p</italic>&#x2009;&#x003C;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">24.</td>
<td valign="top" align="left">Asingwire 2019</td>
<td valign="top" align="left">Uganda</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">Districts</td>
<td valign="top" align="left">5,012 youth aged 15&#x2013;24 years</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Intensified YFS (distribution of fliers, video clips, SMS, IEC/SBCC, counseling, FP distribution for free)<break/><bold>Arm 2:</bold> Control</td>
<td valign="top" align="left">Higher reduction of the probability of pregnancy in the intervention arm compared to control arm (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">25.</td>
<td valign="top" align="left">Doyle 2010</td>
<td valign="top" align="left">Tanzania</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">Rural community, health facilities y and schools</td>
<td valign="top" align="left">Adolescents (Young people who attended year 6, 7 and 8 schools)</td>
<td valign="top" align="left"><bold>Arm 1:</bold> School SRHE (by teachers, participatory drama), YFRHS <italic>via</italic> education of health workers, condom promotion and community activities <bold>Arm 2:</bold> Control</td>
<td valign="top" align="left">&#x00A0;Nearly 102/3,276 (3&#x0025;) girls in the intervention arm compared to 91/3,238 (3&#x0025;) in the comparison arm (AOR 1.09, 95&#x0025; CI, 0.94, 1.26) (<italic>p</italic>&#x2009;&#x003E;&#x2009;0.05).</td>
</tr>
<tr>
<td valign="top" align="left">26.</td>
<td valign="top" align="left">Cowan 2010</td>
<td valign="top" align="left">Zimbabwe</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">30 communities in 7 districts in South-Eastern Zimbabwe</td>
<td valign="top" align="left">4,684 youth aged 8&#x2013;22 years</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Community-based multi-component HIV prevention intervention delivered to young people, parents, and clinic staff and was theoretically based in social learning theory<break/><bold>Arm 2:</bold> Control</td>
<td valign="top" align="left">No impact of the intervention on pregnancy rate, which was 5.9&#x0025; in control Vs 5.3&#x0025; in intervention arm AOR 0.83 [0.50&#x2013;1.35] Adjusted for <italic>a priori</italic> confounders (age, strata, marital status &#x0026; education)]. Unmarried women in intervention arm had lower risk becoming pregnant (AOR 0.55, 95&#x0025; CI, 0.32&#x2013;0.95) than those in control arm.</td>
</tr>
<tr>
<td valign="top" align="left">27.</td>
<td valign="top" align="left">Dunbar 2014</td>
<td valign="top" align="left">Zimbabwe</td>
<td valign="top" align="left">RCT</td>
<td valign="top" align="left">Out-of- school high density urban area</td>
<td valign="top" align="left">&#x00A0;315 out-of-school adolescent female orphans (having lost at least one<break/>parent) aged 16&#x2013;19</td>
<td valign="top" align="left"><bold>Arm 1:</bold> Life-skills and health education, vocational training, micro-grants (in the form of capital equipment, supplies or additional training) and social supports)<break/><bold>Arm 2:</bold> Life-skills and health education alone</td>
<td valign="top" align="left">Fewer unintended pregnancies among intervention participants [HR 0.61, 95&#x0025; CI (0.37, 1.01)]</td>
</tr>
<tr>
<td valign="top" align="left">28.</td>
<td valign="top" align="left">Rokicki 2017</td>
<td valign="top" align="left">Ghana</td>
<td valign="top" align="left">CRT</td>
<td valign="top" align="left">38 secondary Schools in Accra</td>
<td valign="top" align="left">756 females students aged 14 to 24 years</td>
<td valign="top" align="left"><bold>Arm1:</bold> Unidirectional intervention <bold>(</bold>text message sent participants text messages with reproductive health information.<break/><bold>Arm 2:</bold> Interactive intervention (engaging adolescents in text messaging reproductive health quizzes.<break/><bold>Arm 3:</bold> Control.</td>
<td valign="top" align="left">Both unidirectional [odds ratio (OR)&#x2009;&#x003D;&#x2009;0.14; 95&#x0025; CI&#x2009;&#x003D;&#x2009;0.03, 0.71] and interactive interventions (OR&#x2009;&#x003D;&#x2009;0.15; 95&#x0025; CI&#x2009;&#x003D;&#x2009;0.03, 0.86) lowered odds of self-reported pregnancy for sexually active participants (at 15 months follow up)</td>
</tr>
<tr>
<td valign="top" align="left">29.</td>
<td valign="top" align="left">Duflo 2021</td>
<td valign="top" align="left" rowspan="3">Ghana</td>
<td valign="top" align="left" rowspan="3">RCT</td>
<td valign="top" align="left" rowspan="3">2,064 students (1,036 females).</td>
<td valign="top" align="left" rowspan="3">Secondary school</td>
<td valign="top" align="left" rowspan="3"><bold>Arm 1:</bold> Scholarship (tuition and exam fee<break/><bold>Arm 2:</bold> Control</td>
<td valign="top" align="left" rowspan="2"><bold>Marriage:</bold> 12 years after the intervention, the likelihood of getting married reduced by 0.096 (<italic>p</italic>&#x2009;&#x003D;&#x2009;0.08) compared to the control mean of 0.53. In 2019, the probability of getting married reduced by 0.062 (<italic>p</italic>&#x2009;&#x003D;&#x2009;0.067) compared to the control mean of 0.475.<break/><bold>Pregnancy:</bold> Scholarship recipients were 0.07(<italic>p</italic>&#x2009;&#x003D;&#x2009;0.037) less likely to have ever been pregnant compared to comparison mean of 0.479.</td>
</tr>
<tr>
<td valign="top" align="left">30.</td>
<td valign="top" align="left" rowspan="2">Dupas 2017</td>
</tr>
<tr>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>Marriage:</bold> Eight years after the intervention, there was 9.1pps less probability of living with partner at age 25 (compared to mean control 0.344).<break/><bold>Pregnancy:</bold> Scholarship recipients were 10.7pp (18&#x0025;) less likely to have ever been pregnant (compared to control mean of 0.583) (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.01)</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="table-fn1"><p><bold>NB:</bold> AOR, Adjusted odds ratio; CCT, Conditional cash transfer; CI, Confidence interval; HR, Hazard ratio; IEC, Information, education and communication; OVC, Orphan and vulnerable children; PP, percentage point; RR, Relative risk; SBCC, Social and behavioral change communication; SRH, Sexual and Reproductive Health; TT, Teachers&#x2019; training; UCCT, Unconditional cash transfer; V, Violence prevention; VE, Violence prevention combined with and education promotion; VEH, Violence, Education and Health; VEHW, Violence prevention, education promotion, health, and wealth creation; YFRHS, Youth friendly reproductive health services; YFS, Youth friendly services.</p></fn>
</table-wrap-foot>
</table-wrap>
<sec id="s3a1"><title>The methodological quality of the included articles</title>
<p>The appraisal scores of the randomized controlled trials and cluster randomized trials are shown in <xref ref-type="app" rid="app1">Appendix 1</xref> and <xref ref-type="app" rid="app2">2</xref> respectively. The scores for the individual and cluster randomized trials ranged from 9/13 to 10/13. Almost all studies could not blind participants, researcher, and data collectors, which is also expected given the nature of the interventions. In addition, few of the studies reported baseline imbalances. In the case of quasi-experimental studies included in this review, the main risk of bias was related to the comparability of the groups even though the primary authors have attempted to account for this effect using analysis.</p>
</sec>
</sec>
</sec>
<sec id="s4"><title>Effectiveness of the intervention on child marriage</title>
<p>The interventions reported in the included papers are broadly classified into one the following categories based on the areas they addressed (health, education, wealth, or community dialogue).
<list>
<list-item><label>a.</label><p>Interventions aimed to build educational assets (E),</p></list-item>
<list-item><label>b.</label><p>Interventions aimed to build life skills and health assets (H),</p></list-item>
<list-item><label>c.</label><p>Interventions aimed to build livelihood and/or financial skills (Wealth building interventions (W),</p></list-item>
<list-item><label>d.</label><p>Interventions aimed to change community norms (Community dialogues to change community norms about women empowerment including gender violence or child marriage or both (C),</p></list-item>
<list-item><label>e.</label><p>Combination of one or more of the above.</p></list-item>
</list>As such some of the projects have addressed more than one of the educational, health and livelihood and community dialogue components. Some comprised four components, some consisted of three components, and others consisted of two components (<xref ref-type="table" rid="T2">Table&#x00A0;2</xref>). Note that some studies were multi-arm designs, and they simultaneously reported the effect of one component, two component, three component and four component interventions. Community dialogue designed for violence prevention has been used both as control and combined with multi-component interventions. It is critical to note that the studies the reported one, two, three and four component interventions were not mutually exclusive, because a single study with multiple arms may report different combinations of interventions and thus contributing to one, two, three and four component interventions. In addition, when we refer to &#x201C;component&#x201D;, we are referring from the perspective of the broader category even though there are narrow multiple interventions within one broad component intervention. For instance, a one component heath intervention may contain training and information on sexual and reproductive health, menstrual hygiene, HIV/AIDS, providing clinic vouchers, etc.
<list>
<list-item><label>A.</label><p>Programs/Projects that addressed four components (Health, Education, Wealth, and community dialogue)</p></list-item>
</list></p>
<table-wrap id="T2" position="float"><label>Table 2</label>
<caption><p>Effectiveness of different categories of interventions on child marriage across the different subgroups and settings.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Intervention type</th>
<th valign="top" align="center">Study ID</th>
<th valign="top" align="center">Country</th>
<th valign="top" align="center">10&#x2013;19</th>
<th valign="top" align="center">Ages 8&#x2013;17</th>
<th valign="top" align="center">Ages 14&#x2013;19</th>
<th valign="top" align="center">Ages l4 years or less</th>
<th valign="top" align="center">Ages 15&#x2013;19</th>
<th valign="top" align="center">Orphans</th>
<th valign="top" align="center">Out of school</th>
<th valign="top" align="center">School Adolescents</th>
<th valign="top" align="center">Ultra-poor households</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" colspan="12"><bold>Four component comprehensive interventions</bold></td>
</tr>
<tr>
<td valign="top" align="left">Violence prevention, health, and educational and wealth promotion</td>
<td valign="top" align="left">Austrian 2022</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>Effective</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Education promotion (<italic>via</italic> CCT), wealth, health promotion plus community dialogue</td>
<td valign="top" align="left">Hegdahl 2021</td>
<td valign="top" align="left">Zambia</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Community dialogue and information on FP and SRH <italic>via</italic> school clubs plus economic incentive in the form of school materials and revolving funds (HEWC)</td>
<td valign="top" align="left">Chow 2021</td>
<td valign="top" align="left">Ethiopia</td>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left" colspan="12"><bold>Three component comprehensive interventions</bold></td>
</tr>
<tr>
<td valign="top" align="left">(UCCT plus CCT PLUS livelihoods and life skills training, mentoring and an asset transfer, with linkages to strengthened government-run HIV and SRH services)</td>
<td valign="top" align="left">Waidler 2022</td>
<td valign="top" align="left">Tanzania</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Effective (among females)</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Violence prevention, health, and educational promotion</td>
<td valign="top" align="left">Austrian 2022</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="2">Combined (school promotion, asset transfer and community dialogue)-HEWC</td>
<td valign="top" align="left">Erulkar 2020</td>
<td valign="top" align="left">Tanzania</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Erulkar 2009</td>
<td valign="top" align="left">Ethiopia</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left">Reverse effect</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left" colspan="12"><bold>Two components</bold></td>
</tr>
<tr>
<td valign="top" align="left">Violence prevention, and education promotion</td>
<td valign="top" align="left">Austrian 2022</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>E</bold>ffective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Empowerment and livelihood and life skills training and RH information (Health and Wealth)</td>
<td valign="top" align="left">Bandiera 2020</td>
<td valign="top" align="left">Uganda</td>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Community dialogue plus information on FP and SRH <italic>via</italic> school clubs (Health and community dialogue)</td>
<td valign="top" align="left">Chow 2021</td>
<td valign="top" align="left">Ethiopia</td>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Social (safe space), health voucher, and wealth (saving account) intervention</td>
<td valign="top" align="left">Austrian 2020</td>
<td valign="top" align="left">Zambia</td>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Social (safe space) and wealth (saving account) intervention</td>
<td valign="top" align="left">Austrian 2020</td>
<td valign="top" align="left">Zambia</td>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Add on HIV education, educational subsidy plus information on condom</td>
<td valign="top" align="left">Dulfo 2015</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Educational subsidy plus Abstinence only HIV curriculum</td>
<td valign="top" align="left">Duflo 2010</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Tuition, material, and economic support (Education and Wealth)</td>
<td valign="top" align="left">Hegdahl 2021</td>
<td valign="top" align="left">Zambia</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left" colspan="12"><bold>Single component</bold></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="2">Community dialogue</td>
<td valign="top" align="left">Erulkar 2020</td>
<td valign="top" align="left">Burkina Faso</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Erulkar 2020</td>
<td valign="top" align="left">Tanzania</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Social (safe space) only intervention</td>
<td valign="top" align="left">Austrian 2020</td>
<td valign="top" align="left">Zambia</td>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" rowspan="4">Education promotion (<italic>via</italic> CCT)</td>
<td valign="top" align="left">Erulkar 2020</td>
<td valign="top" align="left">Burkina Faso</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Erulkar 2020</td>
<td valign="top" align="left">Tanzania</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Hallfors 2011</td>
<td valign="top" align="left">Zimbabwe</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Hallfors 2015</td>
<td valign="top" align="left">Zimbabwe</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left" rowspan="2">Educational subsidy</td>
<td valign="top" align="left">Dulfo 2015 and Duflo 2010</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Duflo 2021</td>
<td valign="top" align="left">Ghana</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Abstinence only HIV education</td>
<td valign="top" align="left">Dulfo 2015 and Duflo 2010</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Conditional asset Transfer alone</td>
<td valign="top" align="left">Erulkar 2020</td>
<td valign="top" align="left">Tanzania</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not Effective</td>
<td valign="top" align="left">Not Effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Conditional cash transfer- short-term (&#x003C;2 years)</td>
<td valign="top" align="left">Baird 2010</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left">Not Effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">CCT-5 year follow up</td>
<td valign="top" align="left">Baird 2016</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">UCCT-short term (&#x2264;2 years)</td>
<td valign="top" align="left">Baird 2010</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">-</td>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">UCCT-Long term (5 years)</td>
<td valign="top" align="left">Baird 2016</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">-</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Cash Transfer (UCCT) for OVC-long term (4 year)</td>
<td valign="top" align="left">Handa 2015</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">UCCT for ultra-poor (2 years</td>
<td valign="top" align="left">UNC 2016</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
</tr>
<tr>
<td valign="top" align="left">UCCT for ultra-poor-30 months in Malawi and 36 months in Zambia</td>
<td valign="top" align="left">Dake 2018</td>
<td valign="top" align="left">Malawi and Zambia (14&#x2013;21 years)</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="table-fn2"><p><bold>NB</bold>: CCT, Conditional cash transfer; FP, Family planning; HEWC, Health, education, wealth, and community dialogue; HIV, Human immune-deficiency virus; SRH, Sexual and Reproductive Health; UCCT, Unconditional cash transfer.</p></fn>
</table-wrap-foot>
</table-wrap>
<p>Out of the studies that comprised four component intervention, three of them reported on marriage outcomes. These projects were conducted in Kenya (<xref ref-type="bibr" rid="B46">46</xref>), Ethiopia (<xref ref-type="bibr" rid="B45">45</xref>) and Zambia (<xref ref-type="bibr" rid="B47">47</xref>). Surprisingly, the effect of these comprehensive interventions comprising violence prevention, heath, education, and wealth components, was not significant when compared to single component intervention (violence prevention) alone. An arm with four component interventions (health, education, wealth, and violence prevention) was not significantly different from an arm with single intervention (violence prevention alone). On the other hand, subgroup analysis indicates that the four-component intervention (intervention with health, education, wealth, and violence prevention) significantly reduced child marriage among baseline out-of-schoolgirls when compared to an arm with violence prevention alone.</p>
<p>Similarly, study conducted in Zambia reported on intervention that comprised health, education and wealth components and community dialogue to change norms around child marriage. The study reported that incidence of marriage before the age of 18 was 21&#x0025; lower among the arm exposed to combinations of intervention that comprised economic support for families and tuition and material support for girls, and sexual and reproductive health education when compared to the control arm with no intervention. This change was not statistically significant (<xref ref-type="bibr" rid="B47">47</xref>).</p>
<p>An Ethiopian study that examined the effect of combined economic intervention, information and community dialogue to change norms around child marriage reported significant effect of the intervention on child marriage among girls aged 8&#x2013;17 years old (<xref ref-type="bibr" rid="B45">45</xref>).
<list list-type="simple">
<list-item><label>B.</label><p>Programs/Projects that addressed three components</p></list-item>
</list>Studies that lie under this category included report on effect of any three combinations of Health/social, Wealth, Education, or Community dialogue. Among the included studies that reported on child marriage, four of them reported on the effect of three component interventions. These projects were conducted in Ethiopia (<xref ref-type="bibr" rid="B44">44</xref>), Kenya (<xref ref-type="bibr" rid="B46">46</xref>), Tanzania (<xref ref-type="bibr" rid="B48">48</xref>). One study was a multicounty study conducted in Tanzania and Burkina Faso (<xref ref-type="bibr" rid="B43">43</xref>). The effect of these multiple component interventions comprising violence prevention, education and health component was not significantly different from that of control arm [standalone (violence prevention) intervention] (<xref ref-type="bibr" rid="B46">46</xref>).</p>
<p>On the other hand, combined interventions comprising school promotion, asset transfer and community dialogue were effective among younger adolescents (less than 14 years of age) in Tanzania (<xref ref-type="bibr" rid="B43">43</xref>) and in Ethiopia (<xref ref-type="bibr" rid="B44">44</xref>). However, in Ethiopia, there was reverse effect among girls aged 15&#x2013;19 years. Girls in treatment arm had 2.4 times higher likelihood of getting married compared to those girls in the control arm (<xref ref-type="bibr" rid="B44">44</xref>).</p>
<p>Tanzanian study reported that girls in an arm with four component interventions comprising &#x201C;Cash PLUS&#x201D; interventions (cash transfer plus livelihoods and life skills training, mentoring and an asset transfer, combined with linkages to strengthened government-run HIV and SRH services), were less likely to enter into marriage compared to the girls in the &#x201C;Cash ONLY&#x201D; arm (arm that received the cash transfer program alone) (<xref ref-type="bibr" rid="B48">48</xref>). The cash transfer involved both unconditional (to reduce vulnerability and increase income) and conditional (up on school enrolment or seeking essential health services).
<list list-type="simple">
<list-item><label>C.</label><p>Programs/Projects that comprised two components</p></list-item>
</list>The five studies included under this category were conducted in Zambia (<xref ref-type="bibr" rid="B47">47</xref>, <xref ref-type="bibr" rid="B49">49</xref>), Uganda (<xref ref-type="bibr" rid="B34">34</xref>), Kenya (<xref ref-type="bibr" rid="B29">29</xref>) and Ethiopia (<xref ref-type="bibr" rid="B45">45</xref>). Some of these interventions focused on health/social and livelihood/wealth (<xref ref-type="bibr" rid="B34">34</xref>); some were focused on health/social and educational support (<xref ref-type="bibr" rid="B47">47</xref>); and others were focused in creating safe spaces and providing health vouchers (<xref ref-type="bibr" rid="B49">49</xref>). Some of these interventions were effective (<xref ref-type="bibr" rid="B34">34</xref>, <xref ref-type="bibr" rid="B46">46</xref>) and some were not (<xref ref-type="bibr" rid="B47">47</xref>).</p>
<p>For instance, a four year follow up study conducted in Uganda reported a significant effect of empowerment and livelihood and life skills training and provision of reproductive health (RH) information (8 pp lower) compared to control communities that did not receive any of the interventions (<xref ref-type="bibr" rid="B34">34</xref>). A Kenyan study found that violence prevention combined with education promotion was more effective (with 6.2 pp less) when compared to violence prevention alone in reducing child marriage among out of school adolescent girls even though the effect was not significant for school adolescent girls (<xref ref-type="bibr" rid="B46">46</xref>). In Kenya, even though education subsidies were effective when implemented alone, they were not effective when combined with national HIV/AIDS curriculum which focuses on abstinence only. In addition, education subsidies when combined with an add on HIV education, and information on condom were not effective in reducing teen pregnancy (<xref ref-type="bibr" rid="B29">29</xref>).</p>
<p>Study conducted in Zambia reported that multicomponent intervention comprising health/social and wealth components (the provision of safe spaces for adolescents combined with heath vouchers and saving accounts) did not have any impact on child marriage when compared to control arm (no intervention) (<xref ref-type="bibr" rid="B49">49</xref>).</p>
<p>Study conducted in Zambia reported that intervention that comprised education and wealth components (financial support to families and girls, tuition, and material support) reduced incidence of marriage before the age of 18 by 14&#x0025; when compared to the control arm with no intervention. This difference was not statistically significant (<xref ref-type="bibr" rid="B47">47</xref>).</p>
<p>Study conducted in Ethiopia that examined the effect of information and community dialogue to change norms around child marriage reported significant effect of the intervention on child marriage among girls aged 8&#x2013;17 years old. In the study, the community dialogue was complemented by the information provided at school clubs on family planning and sexual and reproductive health issues. The approach of community mobilization consisted of training influential community members such as religious leaders, teachers, gender activists, community leaders. These influential community members would then facilitate community conversations to reflect on challenges that girls face when entering marriage and elicit empathy and dispel myths around child marriage (<xref ref-type="bibr" rid="B45">45</xref>).
<list list-type="simple">
<list-item><label>D.</label><p>Projects with one component interventions</p></list-item>
</list>Some of the studies reported above have also provided a report for the arms with single component interventions. Nine of the included studies reported on single component interventions (interventions addressing only either of education, wealth, heath/social and violence prevention categories). Interventions reported under this category include community dialogue (<xref ref-type="bibr" rid="B43">43</xref>), educational support (<xref ref-type="bibr" rid="B27">27</xref>, <xref ref-type="bibr" rid="B37">37</xref>&#x2013;<xref ref-type="bibr" rid="B39">39</xref>), educational subsidies, HIV/AIDS curriculum and livelihood support (UCCT) (<xref ref-type="bibr" rid="B27">27</xref>, <xref ref-type="bibr" rid="B50">50</xref>, <xref ref-type="bibr" rid="B51">51</xref>), creating safe spaces for adolescents (<xref ref-type="bibr" rid="B49">49</xref>).</p>
<p>Particularly impressive result reported from studies under this category is one Ghanaian study with relatively longer duration of follow up (<xref ref-type="bibr" rid="B39">39</xref>). The study reported significant impact of providing scholarship on reducing the probability of ever getting married or living with partners across years of follow up (<xref ref-type="bibr" rid="B39">39</xref>, <xref ref-type="bibr" rid="B40">40</xref>). A multicounty study conducted in Burkina Faso and Tanzania reported that community dialogue alone was effective in reducing child marriage in Burkina Faso [girls in community dialogue arm aged 15&#x2013;17 years had two-thirds less risk (RR&#x2009;&#x003D;&#x2009;0.33; 95&#x0025; CI, 0.19, 0.60) of being married]. The same study reported that the community dialogue does not have significant effect on child marriage on both girls aged 12&#x2013;14 years and 15&#x2013;17 years old in Tanzania (<xref ref-type="bibr" rid="B43">43</xref>). The difference in the effectiveness of the intervention in the two countries may related to the intensity and the approaches of the interventions. The approach utilized in Burkina Faso was recruiting and training community members and training them for five days so that they will mobilize and group the community into groups of 30 people. The groups were provided 16 sessions of training on negative impacts of child marriage and the value of girls&#x0027; education, after which they will devise and implement solutions. Some of the devised strategies include house-to-house campaigns and rewards or punishments to the community members. On the other hand, in Tanzania the approach included recruiting religious leaders and training them for two days on benefits of girls &#x201C;education and benefits of delaying child marriage. The leaders were also trained on how to facilitate discussions and deliver messages letting them deliver messages on routine community meetings such as religious meetings. In addition, in Tanzania, there was no system for sustained contact system to trace the work of the community leaders. The community leaders were not expected to report the community members whom they contacted (<xref ref-type="bibr" rid="B43">43</xref>).</p>
<p>Study conducted in Zimbabwe demonstrated that supporting orphans and vulnerable adolescents to remain in school reduced child marriage both in the short term (2 years) (<xref ref-type="bibr" rid="B37">37</xref>) and long-term (5 years) follow up (<xref ref-type="bibr" rid="B38">38</xref>). The school support covered tuition fees, uniforms, school supplies and assigning helper to monitor participants&#x0027; school attendance.</p>
<p>Study conducted in Malawi reported that there is no significant effect of conditional cash transfer (CCT) on marriage among schoolgirls both in short-term (2 years follow up) and long-term (5 years) follow up. The same study reported statistically significant effect of conditional cash transfer (CCT) among out-of-school girls both in short-term and long-term evaluation. The study also reported that UCCT was effective on baseline schoolgirls during and immediately upon completion, but not in the long-term (after 5 years) (<xref ref-type="bibr" rid="B27">27</xref>).</p>
<p>Using data from a four-year follow up study, a Kenyan study reported that UCCT provided to orphan and vulnerable children has no significant impact on child marriage (<xref ref-type="bibr" rid="B50">50</xref>). Similarly, a Malawian study reported that unconditional Cash transfer (UCCT) to ultra-poor rural households has no significant impact on child marriage (<xref ref-type="bibr" rid="B52">52</xref>). Other multi-country study also reported that unconditional Cash transfer (UCCT) to ultra-poor rural households did not significantly reduce child marriage both in Malawi and Zambia (<xref ref-type="bibr" rid="B51">51</xref>).</p>
<p>Study from Zambia reported that the provision of safe spaces for adolescents when provided alone or when combined with heath vouchers did not have any impact on child marriage when compared to control arm (no intervention) (<xref ref-type="bibr" rid="B49">49</xref>).</p>
</sec>
<sec id="s5"><title>Effectiveness of the intervention on teen pregnancy</title>
<p>The categories of interventions whose effect on teen pregnancy was reported using categories just like that of child marriage described above.
<list>
<list-item><label>A.</label><p>Programs/Projects that addressed four components (Health, Education, Wealth, and community dialogue)</p></list-item>
</list>Studies under these categories comprised interventions addressing combinations of health, education, wealth, and violence prevention. All the three studies comprising four component interventions reported on teen pregnancy. These projects were conducted in Kenya (<xref ref-type="bibr" rid="B42">42</xref>, <xref ref-type="bibr" rid="B46">46</xref>) and Zambia (<xref ref-type="bibr" rid="B53">53</xref>). Surprisingly, the effect of these comprehensive interventions comprising combinations of health, education, wealth, and violence prevention was not significant when compared to control arm (violence prevention intervention alone (<xref ref-type="bibr" rid="B42">42</xref>, <xref ref-type="bibr" rid="B46">46</xref>). Similarly, study conducted in Zambia reported on intervention that comprised health, education and wealth components and community dialogue to change norms around child marriage. The study found no significant effect of the multicomponent intervention on teen pregnancy compared to control arm. The combinations of intervention comprised economic support for families and tuition and material support for girls, and sexual and reproductive health education (<xref ref-type="bibr" rid="B53">53</xref>) (<xref ref-type="table" rid="T3">Table&#x00A0;3</xref>).
<list list-type="simple">
<list-item><label>B.</label><p>Programs/Projects that addressed three components (any three combinations of Health/social, Wealth, Education, or violence prevention)</p></list-item>
</list></p>
<table-wrap id="T3" position="float"><label>Table 3</label>
<caption><p>Effectiveness of different categories of interventions on teen pregnancy across the different subgroups and settings.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Intervention type</th>
<th valign="top" align="center">Study ID</th>
<th valign="top" align="center">Country</th>
<th valign="top" align="center">15&#x2013;24</th>
<th valign="top" align="center">Ages 8&#x2013;17</th>
<th valign="top" align="center">Ages 14&#x2013;19</th>
<th valign="top" align="center">Ages 13&#x2013;14</th>
<th valign="top" align="center">Ages 15&#x2013;17</th>
<th valign="top" align="center">Orphans</th>
<th valign="top" align="center">Out of school</th>
<th valign="top" align="center">School Adolescents</th>
<th valign="top" align="center">Ultra-poor households</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" colspan="12"><bold>Four component comprehensive interventions</bold></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="2">Violence prevention, health, and educational and wealth promotion-HEWC</td>
<td valign="top" align="left">Austrian 2022</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Kangwann 2022</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Education promotion (<italic>via</italic> CCT), wealth, health promotion and life skills plus community dialogue]-HEWC</td>
<td valign="top" align="left">Sinsamala, 2021</td>
<td valign="top" align="left">Zambia</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left" colspan="12"><bold>Three component comprehensive interventions</bold></td>
</tr>
<tr>
<td valign="top" align="left">Cash transfer (UCCT plus CCT (conditioned up on school enrolment and health service utilization) PLUS livelihoods and life skills training, mentoring and an asset transfer, with linkages to strengthened government-run HIV and SRH services)-HEW</td>
<td valign="top" align="left">Waidler 2022</td>
<td valign="top" align="left">Tanzania</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="2">Violence prevention, health, and educational promotion-HEC</td>
<td valign="top" align="left">Austrian 2022</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Kangwann 2022</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Life-skills and health education (HS) and vocational training and micro-grants (W)</td>
<td valign="top" align="left">Dunbar 2014</td>
<td valign="top" align="left">Zimbabwe</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Marginal effect</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left" colspan="12"><bold>Two components</bold></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="2">Violence prevention, and education promotion</td>
<td valign="top" align="left">Austrian 2022</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Marginally effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Kangwann 2022</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Empowerment and livelihood and life skills training and RH information (Health and Wealth)</td>
<td valign="top" align="left">Bandiera 2020</td>
<td valign="top" align="left">Uganda</td>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Add on HIV education, educational subsidy plus information on condom</td>
<td valign="top" align="left">Duflo 2015 and Duflo 2010</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Joint HIV/AIDS curriculum (abstinence only) and provision of uniform (education subsidy)</td>
<td valign="top" align="left">Duflo 2015, Duflo 2010</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Social (safe space) and wealth (saving account) intervention</td>
<td valign="top" align="left">Austrian 2020</td>
<td valign="top" align="left">Zambia</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left">Tuition, material, and economic support (Education and Wealth)</td>
<td valign="top" align="left">Sinsamala 2021</td>
<td valign="top" align="left">Zambia</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"><bold>&#x00A0;</bold></td>
</tr>
<tr>
<td valign="top" align="left" colspan="12"><bold>Single component</bold></td>
</tr>
<tr>
<td valign="top" align="left">School subsidies (fees, uniforms, supplies and a school-based female helper to monitor attendance)</td>
<td valign="top" align="left">Hallfors 2015</td>
<td valign="top" align="left">Zimbabwe</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Reducing cost of education by providing free uniforms</td>
<td valign="top" align="left">Duflo 2006, Duflo 2014</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Covering tuition and exam fees</td>
<td valign="top" align="left">Duflo 2021</td>
<td valign="top" align="left">Ghana</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">HIV education (abstinence only)</td>
<td valign="top" align="left">Duflo 2015</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">HIV education (abstinence only) combined with educational subsidy</td>
<td valign="top" align="left">Duflo 2015</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">School-based SRHE</td>
<td valign="top" align="left">Doyle 2010</td>
<td valign="top" align="left">Tanzania</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">CCT: Short-term (2years)</td>
<td valign="top" align="left">Baird 2016, Baird 2009</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Marginally significant effect</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">CCT: long-term (5 years)</td>
<td valign="top" align="left">Baird 2016</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Marginally effective (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.1)</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">UCCT-short term</td>
<td valign="top" align="left">Baird 2016, Baird 2011</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">UCCT-long term</td>
<td valign="top" align="left">Baird 2016</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Cash transfer (UCCT plus CCT) PLUS livelihoods and life skills training, mentoring and an asset transfer, with linkages to strengthened government-run HIV and SRH services)</td>
<td valign="top" align="left">Waidler 2022</td>
<td valign="top" align="left">Tanzania</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Conditional cash transfer- short-term (&#x003C;2 years)</td>
<td valign="top" align="left">Baird 2010</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left">Not Effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">CCT-5 year follow up</td>
<td valign="top" align="left">Baird 2016</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">UCCT-short term (&#x2264;2 years)</td>
<td valign="top" align="left">Baird 2010</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">-</td>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">UCCT-Long term (5 years)</td>
<td valign="top" align="left">Baird 2016</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">-</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Cash Transfer (UCCT) for OVC-long term (4 year)</td>
<td valign="top" align="left">Handa 2015</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">UCCT for ultra-poor (2 years</td>
<td valign="top" align="left">UNC 2016</td>
<td valign="top" align="left">Malawi</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
</tr>
<tr>
<td valign="top" align="left">UCCT for ultra-poor-30 months in Malawi and 36 months in Zambia</td>
<td valign="top" align="left">Dake 2018</td>
<td valign="top" align="left">Malawi and Zambia</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
</tr>
<tr>
<td valign="top" align="left">Intensifying SRH services</td>
<td valign="top" align="left">Asingwire 2019</td>
<td valign="top" align="left">Uganda</td>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Social (safe space) only intervention</td>
<td valign="top" align="left">Austrian 2020</td>
<td valign="top" align="left">Zambia</td>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">School SRHE (led by teachers, participatory drama), YFRHS <italic>via</italic> education of HCWs, condom promotion and community activities to create supportive environments</td>
<td valign="top" align="left">Doyle 2010</td>
<td valign="top" align="left">Tanzania</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">HIV relative risk (RR) communication by age</td>
<td valign="top" align="left">Dupas 2011, Duflo 2006</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">HIV/AIDS curriculum (abstinence only)</td>
<td valign="top" align="left">Dupas 2011</td>
<td valign="top" align="left">Kenya</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Community-based multi-component HIV prevention</td>
<td valign="top" align="left">Cowan 2010</td>
<td valign="top" align="left">Zimbabwe</td>
<td valign="top" align="left">Not effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Text messaging reproductive health information</td>
<td valign="top" align="left">Rcokicki 2017</td>
<td valign="top" align="left">Ghana</td>
<td valign="top" align="left">Effective</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="table-fn3"><p><bold>NB</bold>: CCT, Conditional cash transfer; FP, Family planning; HEWC, Health, education, wealth, and community dialogue; HIV/AIDS, Human immune-deficiency virus and acquired immunodeficiency syndrome; SRH, Sexual and Reproductive Health; UCCT, Unconditional cash transfer.</p></fn>
<fn id="table-fn4"><p>Interventions were considered effective if <italic>p</italic>&#x2009;&#x003C;&#x2009;0.05, marginally effective if 0.05&#x2009;&#x003C;&#x2009;<italic>p</italic>&#x2009;&#x003C;&#x2009;0.1 and not effective if <italic>p</italic>&#x2009;&#x003E;&#x2009;0.1 and reverse effect if the intervention resulted in increment in teen pregnancy or early marriage relative to control arm.</p></fn>
</table-wrap-foot>
</table-wrap>
<p>Three studies reported on interventions that addressed three component interventions that addressed any combinations of health, wealth, education, and violence prevention. These projects were conducted Kenya (<xref ref-type="bibr" rid="B42">42</xref>, <xref ref-type="bibr" rid="B46">46</xref>) and Tanzania (<xref ref-type="bibr" rid="B48">48</xref>). The two Kenyan studies conducted both in slum (<xref ref-type="bibr" rid="B42">42</xref>) and pastoral (<xref ref-type="bibr" rid="B46">46</xref>) settings reported that effect of these multiple component interventions comprising violence prevention, education and health was not significantly different from that of standalone (violence prevention) intervention. Similarly, a Tanzanian study reported there was no significant difference in the rates of teen pregnancy among girls in an arm with multicomponent interventions compared to those girls in the &#x201C;cash only&#x201D; arm (arm that received the cash transfer program alone) (<xref ref-type="bibr" rid="B48">48</xref>). The multicomponent interventions comprised cash transfer conditioned up on school enrolment or seeking essential health services and unconditional cash transfer plus livelihoods and life skills training, mentoring and an asset transfer, combined with linkages to strengthened government-run HIV and SRH services).
<list list-type="simple">
<list-item><label>C.</label><p>Programs/Projects that addressed two components</p></list-item>
</list>These projects were conducted in Zambia (<xref ref-type="bibr" rid="B49">49</xref>, <xref ref-type="bibr" rid="B53">53</xref>), Malawi (<xref ref-type="bibr" rid="B27">27</xref>) and Kenya (<xref ref-type="bibr" rid="B46">46</xref>). Some of these interventions were focused on health/social and educational support (<xref ref-type="bibr" rid="B53">53</xref>); some were focused on creating safe spaces and providing health vouchers, (Austrian 2020) and others were focused on educational support and livelihood support through CCT and UCCT (<xref ref-type="bibr" rid="B27">27</xref>). Some of these interventions were effective (<xref ref-type="bibr" rid="B46">46</xref>) and some were not (<xref ref-type="bibr" rid="B53">53</xref>).</p>
<p>A Kenyan study conducted in pastoral setting found that violence prevention combined with education promotion reduced teen pregnancy by one third (marginally significant); on the other hand, the effect was statistically significant for out of schoolgirls (<xref ref-type="bibr" rid="B46">46</xref>). Study in the same country found no significant effect of violence prevention combined with education promotion on teen pregnancy in urban informal settlement setting (<xref ref-type="bibr" rid="B42">42</xref>). Another Kenyan study reported that education subsidies are not effective in reducing teen pregnancy when combined with national HIV/AIDS curriculum which focuses on abstinence only messages. In addition, education subsidies when combined with an add on HIV education, and information on condom were not effective in reducing teen pregnancy (<xref ref-type="bibr" rid="B29">29</xref>). A Zimbabwean study conducted among urban out-of-school youth reported that combining livelihood intervention (vocational training and micro-grants) with life-skills and health education had only marginal effect on teen pregnancy when compared to life-skills and health education [HR 0.61, 95&#x0025; CI, (0.37, 1.01)] (<xref ref-type="bibr" rid="B41">41</xref>).</p>
<p>Study from Zambia reported that intervention with health/social and wealth components was not effective. The study found that the provision of safe spaces for adolescents when combined with heath vouchers and heath saving accounts did not have any impact on teen pregnancy when compared to control arm (no intervention) (<xref ref-type="bibr" rid="B49">49</xref>).
<list list-type="simple">
<list-item><label>D.</label><p>Projects with one component interventions</p></list-item>
</list>Projects under this category include educational support (<xref ref-type="bibr" rid="B27">27</xref>, <xref ref-type="bibr" rid="B37">37</xref>&#x2013;<xref ref-type="bibr" rid="B39">39</xref>) and livelihood support (UCCT) (<xref ref-type="bibr" rid="B50">50</xref>&#x2013;<xref ref-type="bibr" rid="B52">52</xref>), creating safe spaces for adolescents (<xref ref-type="bibr" rid="B49">49</xref>, <xref ref-type="bibr" rid="B54">54</xref>), adolescent sexual and reproductive health education (<xref ref-type="bibr" rid="B55">55</xref>) and HIV prevention interventions (<xref ref-type="bibr" rid="B29">29</xref>, <xref ref-type="bibr" rid="B35">35</xref>, <xref ref-type="bibr" rid="B36">36</xref>).</p>
<p>Like in the case of child marriage, the study conducted in Ghana reported significant impact of provision of scholarship in reducing the probability of ever getting pregnant consistently across years (<xref ref-type="bibr" rid="B39">39</xref>, <xref ref-type="bibr" rid="B40">40</xref>). Study conducted in Zimbabwe demonstrated that supporting orphans and vulnerable adolescents <italic>via</italic> School subsidies (fees, uniforms and supplies) reduced teen pregnancy both in the short term (2 years) (<xref ref-type="bibr" rid="B37">37</xref>) and long-term (5 years) follow ups (<xref ref-type="bibr" rid="B38">38</xref>). Study conducted in Malawi reported that there is no significant effect of conditional cash transfer (CCT) on marriage among schoolgirls both in short-term (2 years follow up) and long-term (5 years) follow up. The same study reported statistically significant effect of conditional cash transfer (CCT) among drop-out girls both in short-term and long-term evaluation. The study also reported that UCCT was effective on baseline schoolgirls during and immediately upon completion, but not in the long-term (after 5 years) (<xref ref-type="bibr" rid="B27">27</xref>).</p>
<p>Using data from a four-year follow up study, a Kenyan study reported that UCCT to orphan and vulnerable children significantly reduced the risk of teen pregnancy (<xref ref-type="bibr" rid="B50">50</xref>). On the other hand, a Malawian study reported that unconditional Cash transfer (UCCT) to ultra-poor rural households has no significant impact on teen pregnancy (<xref ref-type="bibr" rid="B52">52</xref>). Other multi-country study also reported that unconditional Cash transfer (UCCT) to ultra-poor rural households did not significantly reduce the risk of teen pregnancy both in Malawi and Zambia (<xref ref-type="bibr" rid="B51">51</xref>).</p>
<p>From HIV prevention projects, national HIV/AIDS curriculum that focuses on abstinence only was not effective. On the other hand, HIV prevention messages were effective in reducing teen pregnancy (<xref ref-type="bibr" rid="B29">29</xref>). Communicating HIV risk based on age and sex profile reduced teen pregnancy by 27.7&#x0025; (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.05). Communicating the risk averts 29.4 pregnancies by older partners. Communicating HIV risk information decreased the incidence of cross-generational pregnancies by 61.7&#x0025; (relative to the comparison) (<xref ref-type="bibr" rid="B35">35</xref>, <xref ref-type="bibr" rid="B36">36</xref>). On the other hand, a study conducted in Zimbabwe reported that community-based multi-component HIV prevention intervention does not have significant effect on teen pregnancy (<xref ref-type="bibr" rid="B56">56</xref>).</p>
<p>While school sexual and reproductive health education did not have significant impact on teen pregnancy in Tanzania (<xref ref-type="bibr" rid="B55">55</xref>), intensifying adolescent sexual and reproductive health services reduced teen pregnancy in Uganda (<xref ref-type="bibr" rid="B54">54</xref>). Another intervention with important consideration was text messaging of reproductive health information. A Ghanaian study reported that both unidirectional [odds ratio (OR)&#x2009;&#x003D;&#x2009;0.14; 95&#x0025; CI&#x2009;&#x003D;&#x2009;0.03, 0.71] and interactive messages containing reproductive health information (OR&#x2009;&#x003D;&#x2009;0.15; 95&#x0025; CI&#x2009;&#x003D;&#x2009;0.03, 0.86) lowered odds of self-reported pregnancy for sexually active participants (at 15 months follow up) (<xref ref-type="bibr" rid="B57">57</xref>).</p>
<p>The other important interventions under this category are creating safe spaces for adolescents. Study from Zambia reported that the provision of safe spaces for adolescents when provided alone or when combined with heath vouchers did not have any impact on teen pregnancy when compared to control arm (no intervention) (<xref ref-type="bibr" rid="B49">49</xref>).</p>
</sec>
<sec id="s6" sec-type="discussion"><title>Discussions</title>
<p>This review attempted to search and locate the current available evidence on the effectiveness of interventions that have been implemented to reduce teen pregnancy and child marriage in sub-Saharan Africa. The interventions reported in the review were generally categorized into (a) Interventions aimed to build educational assets (E), (b) Interventions aimed to build life skills and health assets (H), (c) Interventions aimed to build livelihood and/or financial skills [Wealth building interventions (W)], (d) Interventions designed to change community norms [including violence prevention, women and girls&#x0027; empowerment and/or prevention of early marriage (C) and e] Combination of one or more of the above.</p>
<p>Even though the amount of investment in multi-component interventions is remarkable, their (additional) effect on child marriage and teen pregnancy is not significant. For instance, multicomponent interventions comprising as many as four domains of interventions were not effective. This might have been because of the lack of focus or logistical difficulties related the implementation. The other inherent problem of studies with multiple domains of interventions is that they had multiple outcomes and they were not powered enough to detect differences in child marriage or teen pregnancy. Besides that, some lacked adequate balance at baseline. In addition, adolescent-based interventions were only subcomponents of the bigger development packages (<xref ref-type="bibr" rid="B48">48</xref>). The strength of such interventions, on the other hand, is that they have collected data on several health and economic variables, and it is clear to understand the modifying effect of several variables and the overall fit of the interventions within the educational, social, economic and health systems of the population. In addition, it will provide an opportunity for understanding the pathways through which the intervention affects the outcomes (child marriage and teen pregnancy). For instance, unconditional cash transfer (UCCT) (<xref ref-type="bibr" rid="B50">50</xref>) was effective in reducing teen pregnancy but not on reducing child marriage. From its effect on schooling, it was possible to hypothesize that the intervention reduced teen pregnancy rate not by delaying marriage, but by keeping adolescent girls in schools. Findings of the study conducted in Malawi also suggests that unconditional cash transfer programs implemented among in-school girls were only effective in the short-term (while the program was in place) (<xref ref-type="bibr" rid="B58">58</xref>). This may be due the fact that girls may not build assets using the short-term funding from the UCCT. On the other hand, the conditional cash transfer (CCT) was effective among out-of-school girls both in short-term and long-term follow ups and it was not effective both in short-term and long-term among in-school girls (<xref ref-type="bibr" rid="B58">58</xref>).</p>
<p>Even though it is difficult to conclude, it appears that interventions with fewer domains were promisingly effective. For instance, interventions such as education subsidies were effective when implemented alone and not effective when combined with other interventions, such as the national HIV curriculum which focuses on abstinence only prevention messages (<xref ref-type="bibr" rid="B29">29</xref>). School promotion interventions were effective in reducing both teen pregnancy and child marriage (<xref ref-type="bibr" rid="B29">29</xref>, <xref ref-type="bibr" rid="B37">37</xref>&#x2013;<xref ref-type="bibr" rid="B39">39</xref>). Particularly, study conducted in Ghana, which had a follow up period of 12 years demonstrated that provision of scholarship that covers secondary school tuition and exam fees significantly reduces marriage and pregnancy (<xref ref-type="bibr" rid="B39">39</xref>). Previous observational study reporting on multi-country data has also reported the effectiveness of eliminating primary school education fees in reducing child marriage (<xref ref-type="bibr" rid="B59">59</xref>). This underscores that addressing barriers to attending secondary school is critical not only in keeping adolescents in school but also in helping them to be empowered and delay their start of childbearing. This is in line with the findings that indicate life skills and livelihood training and mentoring interventions are effective in reducing child marriage (<xref ref-type="bibr" rid="B34">34</xref>, <xref ref-type="bibr" rid="B48">48</xref>).</p>
<p>Examining the population subgroup indicates that some of the interventions were effective only among out-of-school adolescent girls, while their effect among in-school adolescent girls were not significant. For instance, study conducted in Kenya reported that the effect of the multicomponent interventions was greater among girls not in school at baseline. For instance, the intervention comprising violence prevention, education, health and wealth (VEHW) components significantly reduced child marriage compared to the control arm (violence prevention alone) among girls not in school at baseline. On the other hand, the effect was not statistically significant among the full sample (<xref ref-type="bibr" rid="B46">46</xref>). In addition, study conducted in Malawi found that conditional cash transfer (CCT) programs were effective both in short term and long term follow ups among out-of-school girls, but not among in-schoolgirls (<xref ref-type="bibr" rid="B58">58</xref>). While the mechanism is still not clear, some suggest that this may be through increasing educational outcomes (Kangwann 2022) and through tackling cost related barriers, especially among the neediest segments of the population, such as orphans (Hallfors 2015). This especially holds true for girls who could not continue schooling because of financial barriers and potentially financial barriers are really forcing girls to enter marriage early. On the other hand, some interventions, such as community dialogue were effective in reducing child marriage without impacting educational outcomes (Chow 2021). Clarifying such controversies with strong study designs might help in understanding pathways on how the interventions work.</p>
<p>Though routine adolescent sexual and reproductive health services were not effective (<xref ref-type="bibr" rid="B55">55</xref>), intensifying Youth Friendly Services (YFS) through youth corners, outreach, social and behavior change communication intervention (SBCC), counseling, family planning (<xref ref-type="bibr" rid="B60">60</xref>), was effective in reducing teen pregnancy. In addition, text-messages containing reproductive health information were effective (<xref ref-type="bibr" rid="B57">57</xref>). This is promising result as expansion of mobile technologies are increasing.</p>
<p>The other intervention that is promising, if implemented systematically, is community dialogue (<xref ref-type="bibr" rid="B43">43</xref>, <xref ref-type="bibr" rid="B45">45</xref>). However, for community dialogues to be effective, there should be intensive training for the facilitators and appropriate sustainable strategy to trace the activities of community leaders. For instance, the community dialogue in Burkina Faso that used intensive training and sustained reporting and tracing mechanism was successful. On the other hand, community dialogue in Tanzania that was intense and that lacked sustained contact system was not effective (<xref ref-type="bibr" rid="B43">43</xref>). In addition, community dialogue has been implemented as part of other interventions (<xref ref-type="bibr" rid="B43">43</xref>, <xref ref-type="bibr" rid="B45">45</xref>, <xref ref-type="bibr" rid="B47">47</xref>). Especially, when implemented along with other interventions that are delivered through school clubs, it will increase the effect of the intervention by letting adolescent girls get adequate information to backlash misperceptions or negative interactions from the community potentially resulting from exposure to low intensity or inadequate exposure to community conversations about reducing child marriage (<xref ref-type="bibr" rid="B45">45</xref>).</p>
<p>While interpreting the effectiveness of the interventions, it is critical to take the local context into account. For instance, local security situations affect not only the effect of the interventions but also the fidelity of the interventions and the intervention uptakes. In addition, factors associated with instability (<xref ref-type="bibr" rid="B61">61</xref>) and migration (<xref ref-type="bibr" rid="B43">43</xref>) also challenge progress in the evidence base to the reduction of teen pregnancy and child marriage particularly among more vulnerable population groups in rural settings. The other critical thing that should be considered is that the effect of some interventions may cease if there is no means to accommodate their running costs and sustain them, such as the cash transfer programs (<xref ref-type="bibr" rid="B58">58</xref>). This implies that any innovative intervention should be sustainable, economically and politically. There is room for innovation on what might work to reduce child marriage and teen pregnancy in Sub-Saharan Africa where child marriage has remained high. In addition, because of the high demand for such interventions in fragile and humanitarian contexts, there should be an innovative mechanism to design context-specific interventions and strategies for follow up. Even though there are few studies among refugees, some were not powered for the outcome, and/or they did not include child marriage as primary outcomes (<xref ref-type="bibr" rid="B62">62</xref>, <xref ref-type="bibr" rid="B63">63</xref>).</p>
<p>The current review has attempted to look broadly at evidence regarding effective interventions in reducing child marriage and teen pregnancy in sub-Saharan Africa. The review was comprehensive in addressing both published and unpublished articles. However, it is important to acknowledge certain limitations of the review. First, the review did not address studies reported in languages other than English. This is particularly a significant limitation given that Central and West Africa, which are largely Francophone, have some of the highest fertility and lowest contraceptive use levels in Africa and may have attracted interventions with fertility-related outcomes that are not published in English.</p>
<p>The review underscores the need for high quality research to guide program and policy options in achieving demographic transition in Africa. As described earlier, some interventions did not have adequate follow up period and their long-term effects were not investigated. Therefore, more evidence is needed to inform the design of interventions with potential to impact fertility-related outcomes in SSA.</p>
<p>While the findings of the review should be interpreted in the light of the above limitations, the evidence generated from the review provides clear guidance for understanding current gaps and for designing programs and policies with the potential to affect child marriage and teen pregnancy in sub-Saharan Africa.</p>
</sec>
<sec id="s7" sec-type="conclusions"><title>Conclusions</title>
<sec id="s7a"><title>Recommendations for research</title>
<p>The available evidence on the effectiveness of interventions on teen pregnancy, and child marriage is of limited quality due to the limited number of studies that have evaluated these outcomes and because of design limitations of the studies. Additionally, practical, ethical, and contextual information should be sought before implementing certain incentive-based programs. The potential for cost containment and sustainability issues should be addressed. Hence, future trials may integrate costing component. An especially important potential research agenda in Sub-Saharan Africa is exploratory qualitative studies to assess perceptions and views of various groups (urban-rural, religious groups, gender, age, policy-community leaders, etc.) on the role of financial incentives and life skills, and livelihood interventions in delaying marriage and empowering adolescents in the region. In addition, the involvement of different stakeholders, governmental and nongovernmental actors and funders is critical to get insights related to the long-term sustainability of possible interventions. Following the exploratory research, rigorous studies should be designed to delay child marriage by keeping adolescent girls in school longer and transitioning them to secondary school.</p>
<p>In addition, gender, and women&#x0027;s (and girls&#x0027;) empowerment initiatives are often poorly conceptualized and implemented. Research is needed to understand what these mean in high fertility settings and how such empowerment can be achieved in that context and to assess the effectiveness of such empowerment interventions on contraceptive use, pregnancy rates, fertility, and age at first marriage. Young people are key to achieving rapid and sustained decline in fertility in SSA. How to engage them meaningfully remains a challenge where further evidence is needed. Simply having youth centers has been shown not to work. Intensifying efforts to reach them with services <italic>via</italic> multiple strategies have been shown to be effective. There is a need to better understand strategies and mechanisms to reach adolescents and to change their fertility preference and behavior, and to empower them to make independent decisions about their lives and future, including reproductive life. Moreover, there is potential innovation room for utilizing mobile technologies to reduce teen pregnancy and child marriage.</p>
</sec>
<sec id="s7b"><title>Recommendations for policy and practice</title>
<p>Emerging evidence indicates that addressing community dialogues, school subsidies and cash transfer to orphans and vulnerable groups were effective in reducing child marriage across contexts. In addition, tailored interventions, such as intensifying sexual and reproductive health services and using text messages to convey reproductive health information are effective in reducing teen pregnancy among adolescent girls. Therefore, supporting adolescent girls to stay in schools through education subsidies, and/or covering tuition and exam fees and the use of tailored sexual and reproductive health information may reduce teen pregnancies and child marriage. In addition, it is critical to use community dialogue to clarify and address cultural norms around child marriage.</p>
</sec>
</sec>
</body>
<back>
<sec id="s11" sec-type="data-availability"><title>Data availability statement</title>
<p>The original contributions presented in the study are included in the article/<xref ref-type="sec" rid="s14"><bold>Supplementary Materials</bold></xref>, further inquiries can be directed to the corresponding author.</p>
</sec>
<sec id="s12"><title>Author contributions</title>
<p>All authors contributed to conception of the study, methodology, data curation, validation, visualization, data analysis, drafting and critically revising the paper, gave final approval of the version to be published, and agree to be accountable for all aspects of the work. All authors contributed to the article and approved the submitted version.</p>
</sec>
<sec id="s13" sec-type="COI-statement"><title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="s15" sec-type="disclaimer"><title>Publisher&#x0027;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec id="s14" sec-type="supplementary-material"><title>Supplementary material</title>
<p>The Supplementary Material for this article can be found online at: <ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/frph.2023.1105390/full#supplementary-material">https://www.frontiersin.org/articles/10.3389/frph.2023.1105390/full&#x0023;supplementary-material</ext-link>.</p>
<supplementary-material id="SD1" content-type="local-data">
<media mimetype="application" mime-subtype="vnd.openxmlformats-officedocument.wordprocessingml.document" xlink:href="Table1.docx"/>
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<ref id="B53"><label>53.</label><citation citation-type="book"><person-group person-group-type="author"><name><surname>Sinsamala</surname><given-names>RM</given-names></name></person-group>. <source>The effect of sexual and reproductive health education and community dialogue on adolescent pregnancy rates: A cluster randomized trial in a rural Zambian context</source>. <publisher-name>Bergen: The University of Bergen</publisher-name> (<year>2021</year>).</citation></ref>
<ref id="B54"><label>54.</label><citation citation-type="other"><person-group person-group-type="author"><name><surname>Asingwire</surname><given-names>N</given-names></name><name><surname>Muhangi</surname><given-names>D</given-names></name><name><surname>Kyomuhendo</surname><given-names>S</given-names></name><name><surname>Leight</surname><given-names>J</given-names></name></person-group>. <comment>Impact evaluation of youth-friendly family planning services in Uganda. (2019). Accessed March 2023 from <ext-link ext-link-type="uri" xlink:href="https://www.3ieimpact.org/sites/default/files/2019-04/GFR-UPW.06-IE-SEDC-Youth-Friendly-Family-Planning-Uganda.pdf">https://www.3ieimpact.org/sites/default/files/2019-04/GFR-UPW.06-IE-SEDC-Youth-Friendly-Family-Planning-Uganda.pdf</ext-link></comment>.</citation></ref>
<ref id="B55"><label>55.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Doyle</surname><given-names>AM</given-names></name><name><surname>Ross</surname><given-names>DA</given-names></name><name><surname>Maganja</surname><given-names>K</given-names></name><name><surname>Baisley</surname><given-names>K</given-names></name><name><surname>Masesa</surname><given-names>C</given-names></name><name><surname>Andreasen</surname><given-names>A</given-names></name><etal/></person-group> <article-title>Long-term biological and behavioural impact of an adolescent sexual health intervention in Tanzania: follow-up survey of the community-based mema kwa vijana trial</article-title>. <source>PLoS Med</source>. (<year>2010</year>) <volume>7</volume>(<issue>6</issue>):<fpage>e1000287</fpage>. <pub-id pub-id-type="doi">10.1371/journal.pmed.1000287</pub-id><pub-id pub-id-type="pmid">20543994</pub-id></citation></ref>
<ref id="B56"><label>56.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cowan</surname><given-names>FM</given-names></name><name><surname>Pascoe</surname><given-names>SJ</given-names></name><name><surname>Langhaug</surname><given-names>LF</given-names></name><name><surname>Mavhu</surname><given-names>W</given-names></name><name><surname>Chidiya</surname><given-names>S</given-names></name><name><surname>Jaffar</surname><given-names>S</given-names></name><etal/></person-group> <article-title>The regai dzive shiri project: results of a randomised trial of an hiv prevention intervention for Zimbabwean youth</article-title>. <source>AIDS (London, England)</source>. (<year>2010</year>) <volume>24</volume>(<issue>16</issue>):<fpage>2541</fpage>. <pub-id pub-id-type="doi">10.1097/QAD.0b013e32833e77c9</pub-id><pub-id pub-id-type="pmid">20881473</pub-id></citation></ref>
<ref id="B57"><label>57.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Rokicki</surname><given-names>S</given-names></name><name><surname>Cohen</surname><given-names>J</given-names></name><name><surname>Salomon</surname><given-names>JA</given-names></name><name><surname>Fink</surname><given-names>G</given-names></name></person-group>. <article-title>Impact of a text-messaging program on adolescent reproductive health: a cluster-randomized trial in Ghana</article-title>. <source>Am J Public Health</source>. (<year>2017</year>) <volume>107</volume>(<issue>2</issue>):<fpage>298</fpage>&#x2013;<lpage>305</lpage>. <pub-id pub-id-type="doi">10.2105/AJPH.2016.303562</pub-id><pub-id pub-id-type="pmid">27997236</pub-id></citation></ref>
<ref id="B58"><label>58.</label><citation citation-type="other"><person-group person-group-type="author"><name><surname>Baird</surname><given-names>S</given-names></name><name><surname>Chirwa</surname><given-names>E</given-names></name><name><surname>McIntosh</surname><given-names>C</given-names></name><name><surname>Ozler</surname><given-names>B</given-names></name></person-group>. <comment>What happens once the intervention ends? The medium-term impacts of a cash transfer programme in malawi, 3ie grantee final report. New Delhi: International Initiative for Impact Evaluation (3ie). (2015)</comment>.</citation></ref>
<ref id="B59"><label>59.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Koski</surname><given-names>A</given-names></name><name><surname>Strumpf</surname><given-names>EC</given-names></name><name><surname>Kaufman</surname><given-names>JS</given-names></name><name><surname>Frank</surname><given-names>J</given-names></name><name><surname>Heymann</surname><given-names>J</given-names></name><name><surname>Nandi</surname><given-names>A</given-names></name></person-group>. <article-title>The impact of eliminating primary school tuition fees on child marriage in sub-saharan Africa: a quasi-experimental evaluation of policy changes in 8 countries</article-title>. <source>PLoS One</source>. (<year>2018</year>) <volume>13</volume>(<issue>5</issue>):<fpage>e0197928</fpage>. <pub-id pub-id-type="doi">10.1371/journal.pone.0197928</pub-id><pub-id pub-id-type="pmid">29795648</pub-id></citation></ref>
<ref id="B60"><label>60.</label><citation citation-type="book"><person-group person-group-type="author"><name><surname>Asingwire</surname><given-names>N</given-names></name><name><surname>Muhangi</surname><given-names>D</given-names></name><name><surname>Kyomuhendo</surname><given-names>S</given-names></name><name><surname>Leight</surname><given-names>J</given-names></name></person-group>. <source>Impact evaluation of youth-friendly family planning services in Uganda</source>. <publisher-loc>Delhi</publisher-loc>: <publisher-name>International Initiative for Impact Evaluation (3ie)</publisher-name> (<year>2019</year>).</citation></ref>
<ref id="B61"><label>61.</label><citation citation-type="other"><person-group person-group-type="author"><name><surname>Buehren</surname><given-names>N</given-names></name><name><surname>Chakravarty</surname><given-names>S</given-names></name><name><surname>Goldstein</surname><given-names>M</given-names></name><name><surname>Slavchevska</surname><given-names>V</given-names></name><name><surname>Sulaiman</surname><given-names>M</given-names></name></person-group>. <comment>Adolescent girls&#x2019; empowerment in conflict-affected settings: Experimental evidence from south sudan. Working Paper. (2017)</comment>.</citation></ref>
<ref id="B62"><label>62.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Stark</surname><given-names>L</given-names></name><name><surname>Asghar</surname><given-names>K</given-names></name><name><surname>Seff</surname><given-names>I</given-names></name><name><surname>Yu</surname><given-names>G</given-names></name><name><surname>Gessesse</surname><given-names>TT</given-names></name><name><surname>Ward</surname><given-names>L</given-names></name><etal/></person-group> <article-title>Preventing violence against refugee adolescent girls: findings from a cluster randomised controlled trial in Ethiopia</article-title>. <source>BMJ Global Health</source>. (<year>2018</year>) <volume>3</volume>(<issue>5</issue>):<fpage>e000825</fpage>. doi: 10.1136/bmjgh-2018-000825<pub-id pub-id-type="pmid">30398223</pub-id></citation></ref>
<ref id="B63"><label>63.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Stark</surname><given-names>L</given-names></name><name><surname>Seff</surname><given-names>I</given-names></name><name><surname>Asghar</surname><given-names>K</given-names></name><name><surname>Roth</surname><given-names>D</given-names></name><name><surname>Bakamore</surname><given-names>T</given-names></name><name><surname>MacRae</surname><given-names>M</given-names></name><etal/></person-group> <article-title>Building caregivers&#x2019; emotional, parental and social support skills to prevent violence against adolescent girls: findings from a cluster randomised controlled trial in democratic Republic of Congo</article-title>. <source>BMJ Global Health</source>. (<year>2018</year>) <volume>3</volume>(<issue>5</issue>):<fpage>e000824</fpage>. doi: 10.1136/bmjgh-2018-000824<pub-id pub-id-type="pmid">30398222</pub-id></citation></ref></ref-list>
<app-group><app id="app1"><title>APPENDIX 1 Appraisal scores of Randomized trials.</title>
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<th valign="top" align="left">S/N</th>
<th valign="top" align="center">Study ID</th>
<th valign="top" align="center">Q1</th>
<th valign="top" align="center">Q2</th>
<th valign="top" align="center">Q3</th>
<th valign="top" align="center">Q4</th>
<th valign="top" align="center">Q5</th>
<th valign="top" align="center">Q6</th>
<th valign="top" align="center">Q7</th>
<th valign="top" align="center">Q8</th>
<th valign="top" align="center">Q9</th>
<th valign="top" align="center">Q10</th>
<th valign="top" align="center">Q11</th>
<th valign="top" align="center">Q12</th>
<th valign="top" align="center">Q13</th>
<th valign="top" align="center">Score</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">1.</td>
<td valign="top" align="left">Asingwire 2019</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">2.</td>
<td valign="top" align="left">Austrian 2020</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">3.</td>
<td valign="top" align="left">Austrian 2022</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">9/13</td>
</tr>
<tr>
<td valign="top" align="left">4.</td>
<td valign="top" align="left">Baird 2009/10/11</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">5.</td>
<td valign="top" align="left">Baird 2015/16</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">6.</td>
<td valign="top" align="left">Bandiera 2015</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">7.</td>
<td valign="top" align="left">Bandiera 2020</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10.13</td>
</tr>
<tr>
<td valign="top" align="left">8.</td>
<td valign="top" align="left">Cowan 2010</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">9.</td>
<td valign="top" align="left">Dake 2018</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">10.</td>
<td valign="top" align="left">Doyle 2010</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">11.</td>
<td valign="top" align="left">Duflo2006</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">12.</td>
<td valign="top" align="left">Duflo 2010</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
</tr>
<tr>
<td valign="top" align="left">13.</td>
<td valign="top" align="left">Duflo 2015</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">14.</td>
<td valign="top" align="left">Duflo 2021</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">9/13</td>
</tr>
<tr>
<td valign="top" align="left">15.</td>
<td valign="top" align="left">Dupas 2017</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">9/13</td>
</tr>
<tr>
<td valign="top" align="left">16.</td>
<td valign="top" align="left">Dunbar 2014</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">17.</td>
<td valign="top" align="left">Dupas 2011</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">9/13</td>
</tr>
<tr>
<td valign="top" align="left">18.</td>
<td valign="top" align="left">Dupas 2006</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">9/13</td>
</tr>
<tr>
<td valign="top" align="left">19.</td>
<td valign="top" align="left">Hallfors 2011</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">9/13</td>
</tr>
<tr>
<td valign="top" align="left">20.</td>
<td valign="top" align="left">Hallfors 2015</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">9/13</td>
</tr>
<tr>
<td valign="top" align="left">21.</td>
<td valign="top" align="left">Hegdahl 2021</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">22.</td>
<td valign="top" align="left">Handa 2015</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">9/13</td>
</tr>
<tr>
<td valign="top" align="left">23.</td>
<td valign="top" align="left">Kangwann 2022</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">24.</td>
<td valign="top" align="left">Rokicki 2017</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">25.</td>
<td valign="top" align="left">Sinsamala 2021</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">26.</td>
<td valign="top" align="left">UNC 2016</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">10/13</td>
</tr>
<tr>
<td valign="top" align="left">27.</td>
<td valign="top" align="left">Waidler 2022</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">9/13</td>
</tr>
</tbody>
</table>
</table-wrap>
<p><bold>NB:</bold> Q1 Was true randomization used for assignment of participants to treatment groups?</p>
<p>Q2 Was allocation to treatment groups concealed?</p>
<p>Q3 Were treatment groups similar at the baseline?</p>
<p>Q4 Were participants blind to treatment assignment?</p>
<p>Q5 Were those delivering treatment blind to treatment assignment?</p>
<p>Q6 Were outcomes assessors blind to treatment assignment?</p>
<p>Q7 Were treatment groups treated identically other than the intervention of interest?</p>
<p>Q8 Was follow up complete and if not, were differences between groups in terms of their follow up adequately described and analyzed?</p>
<p>Q9 Were participants analyzed in the groups to which they were randomized?</p>
<p>Q10 Were outcomes measured in the same way for treatment groups?</p>
<p>Q11 Were outcomes measured in a reliable way?</p>
<p>Q12 Was appropriate statistical analysis used?</p>
<p>Q13 Was the trial design appropriate, and any deviations from the standard RCT design (individual randomization, parallel groups) accounted for in the conduct and analysis of the trial?</p></app>
<app id="app2"><title>APPENDIX 2 Appraisal scores of quasi-experimental studies.</title>
<table-wrap id="T8" position="float">
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">S/N</th>
<th valign="top" align="center">Study ID</th>
<th valign="top" align="center">Q1</th>
<th valign="top" align="center">Q2</th>
<th valign="top" align="center">Q3</th>
<th valign="top" align="center">Q4</th>
<th valign="top" align="center">Q5</th>
<th valign="top" align="center">Q6</th>
<th valign="top" align="center">Q7</th>
<th valign="top" align="center">Q8</th>
<th valign="top" align="center">Q9</th>
<th valign="top" align="center">Score</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">1.</td>
<td valign="top" align="left">Chow 2021</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">8/9</td>
</tr>
<tr>
<td valign="top" align="left">2.</td>
<td valign="top" align="left">Eruulkar 2009</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">8/9</td>
</tr>
<tr>
<td valign="top" align="left">3.</td>
<td valign="top" align="left">Erulkar 2020</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
<td valign="top" align="left">&#x00A0;</td>
</tr>
</tbody>
</table>
</table-wrap>
<p><bold>NB:</bold></p>
<p>Q1 Is it clear in the study what is the &#x201C;cause&#x201D; and what is the &#x201C;effect&#x201D; (i.e., there is no confusion about which variable comes first)?</p>
<p>Q2 Were the participants included in any comparisons similar?</p>
<p>Q3 Were the participants included in any comparisons receiving similar treatment/care, other than the exposure or intervention of interest?</p>
<p>Q4 Was there a control group?</p>
<p>Q5 Were there multiple measurements of the outcome both pre and post the intervention/exposure?</p>
<p>Q6 Was follow up complete and if not, were differences between groups in terms of their follow up adequately described and analyzed?</p>
<p>Q7 Were the outcomes of participants included in any comparisons measured in the same way?</p>
<p>Q8 Were outcomes measured in a reliable way?</p>
<p>Q9 Was appropriate statistical analysis used?</p></app>
<app id="app3"><title>APPENDIX 3 Full text studies excluded with reasons.</title>
<table-wrap id="T9" position="float">
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">No.</th>
<th valign="top" align="center">Study</th>
<th valign="top" align="center">Reason for exclusion</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">1)</td>
<td valign="top" align="left">Ampt 2020</td>
<td valign="top" align="left">This has addressed commercial sex workers regardless of age</td>
</tr>
<tr>
<td valign="top" align="left">2)</td>
<td valign="top" align="left">Siaplay 2012</td>
<td valign="top" align="left">This is a longitudinal follow up study that used secondary data. It had higher attrition rate. overall response rates of young adults in waves 2, 3, and 4 were 83&#x0025;, 74&#x0025;, and 72&#x0025;, respectively.</td>
</tr>
<tr>
<td valign="top" align="left">3)</td>
<td valign="top" align="left">Heinrich 2016</td>
<td valign="top" align="left">No comparison group</td>
</tr>
<tr>
<td valign="top" align="left">4)</td>
<td valign="top" align="left">Oberth 2021</td>
<td valign="top" align="left">The design was observational (cohort)</td>
</tr>
<tr>
<td valign="top" align="left">5)</td>
<td valign="top" align="left">Koski-2018</td>
<td valign="top" align="left">The design was observational (used DHS data for comparison)</td>
</tr>
<tr>
<td valign="top" align="left">6)</td>
<td valign="top" align="left">Ingwersen 2019</td>
<td valign="top" align="left">No comparison group</td>
</tr>
<tr>
<td valign="top" align="left">7)</td>
<td valign="top" align="left">Hand 2015b</td>
<td valign="top" align="left">Population covered was women of reproductive age (child marriage and teen pregnancy were not covered), but the study addressed TFR, pregnancy rate, etc.</td>
</tr>
<tr>
<td valign="top" align="left">8)</td>
<td valign="top" align="left">Buehren 2017</td>
<td valign="top" align="left">Average age was 22 years (older women). More than a third of participants were already married and had at least 1 child</td>
</tr>
<tr>
<td valign="top" align="left">9)</td>
<td valign="top" align="left">Buehren 2017a</td>
<td valign="top" align="left">There are women who are already in marital union and who had children before the intervention and that proportion is different across treatment arms</td>
</tr>
<tr>
<td valign="top" align="left">10)</td>
<td valign="top" align="left">Miller 2013</td>
<td valign="top" align="left">This is a costing study that considers costs saved by averting HIV infections because of prevention of marriage and increasing income by keeping them in school</td>
</tr>
<tr>
<td valign="top" align="left">11)</td>
<td valign="top" align="left">Erulkar 2017</td>
<td valign="top" align="left">This a costing study</td>
</tr>
<tr>
<td valign="top" align="left">12)</td>
<td valign="top" align="left">Stark 2018a</td>
<td valign="top" align="left">Child marriage for girls already married at baseline was included. The study was not powered for child marriage</td>
</tr>
<tr>
<td valign="top" align="left">13)</td>
<td valign="top" align="left">Stark 2018B</td>
<td valign="top" align="left">Child marriage was not primary outcome</td>
</tr>
<tr>
<td valign="top" align="left">14)</td>
<td valign="top" align="left">Sarnquist 2016</td>
<td valign="top" align="left">Reports pregnancy related dropouts, but not total pregnancies</td>
</tr>
<tr>
<td valign="top" align="left">15)</td>
<td valign="top" align="left">Gavrilovic 2020</td>
<td valign="top" align="left">This is a single time cross-sectional study assessing the impact of productivity safety net program (PSNP) on child marriage rate. The child marriage was estimated by asking women (aged 12&#x2013;19) in the households who have got married before the age of 18 in the last five years or in their lifetime. However, it is difficult to attribute these changes to the intervention because the measurement does not precisely coincide with the timing of the introduction of the intervention. In addition, comparability of the comparison sites was not measured before the introduction of the intervention. The comparative analysis for the two interventions dos does not show effect of the interventions, because comparison between Integrated safety net program (ISNP) and PSNP was made before the ISNP was rolled out.</td>
</tr>
<tr>
<td valign="top" align="left">16)</td>
<td valign="top" align="left">Palermo 2018</td>
<td valign="top" align="left">Baseline imbalance with respect to marriage rates. The design was not focused (it is part of multiple evaluation projects ranging from food consumption shares and other basic needs. The analysis was based on RDD and rather than priori pseudo or true assignment to control and intervention group. The content and detailed description of the intervention specifically targeting adolescents is not clear. In addition, because of lack of priori planning there was no follow up of cohorts of girls, but only estimation of marriage rates in the population, which is further challenging to infer to the effect of the intervention in such design.</td>
</tr>
<tr>
<td valign="top" align="left">17)</td>
<td valign="top" align="left">Austrian 2021</td>
<td valign="top" align="left">The report addressed the effect of the intervention on education, health and economic outcomes, but not on pregnancy and marriage</td>
</tr>
<tr>
<td valign="top" align="left">18)</td>
<td valign="top" align="left">Taylor 2014</td>
<td valign="top" align="left">The report includes the effect of the intervention on attitudinal factors, not changes in marriage and teen pregnancy</td>
</tr>
</tbody>
</table>
</table-wrap></app>
</app-group>
</back>
</article>