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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Rehabil. Sci.</journal-id><journal-title-group>
<journal-title>Frontiers in Rehabilitation Sciences</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Rehabil. Sci.</abbrev-journal-title></journal-title-group>
<issn pub-type="epub">2673-6861</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fresc.2026.1638091</article-id>
<article-version article-version-type="Version of Record" vocab="NISO-RP-8-2008"/>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Review</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Augmented feedback as a therapeutic approach for gait rehabilitation in patients with cerebral palsy: a systematic review</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Hirsch</surname><given-names>Leonie</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref><uri xlink:href="https://loop.frontiersin.org/people/2754060/overview"/><role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="methodology" vocab-term-identifier="https://credit.niso.org/contributor-roles/methodology/">Methodology</role><role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Writing &#x2013; original draft" vocab-term-identifier="https://credit.niso.org/contributor-roles/writing-original-draft/">Writing &#x2013; original draft</role><role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="visualization" vocab-term-identifier="https://credit.niso.org/contributor-roles/visualization/">Visualization</role><role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="conceptualization" vocab-term-identifier="https://credit.niso.org/contributor-roles/conceptualization/">Conceptualization</role><role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Data curation" vocab-term-identifier="https://credit.niso.org/contributor-roles/data-curation/">Data curation</role><role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Formal analysis" vocab-term-identifier="https://credit.niso.org/contributor-roles/formal-analysis/">Formal analysis</role></contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Mrachacz-Kersting</surname><given-names>Natalie</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref><uri xlink:href="https://loop.frontiersin.org/people/39167/overview" /><role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Writing &#x2013; original draft" vocab-term-identifier="https://credit.niso.org/contributor-roles/writing-original-draft/">Writing &#x2013; original draft</role><role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Formal analysis" vocab-term-identifier="https://credit.niso.org/contributor-roles/formal-analysis/">Formal analysis</role><role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="methodology" vocab-term-identifier="https://credit.niso.org/contributor-roles/methodology/">Methodology</role><role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="conceptualization" vocab-term-identifier="https://credit.niso.org/contributor-roles/conceptualization/">Conceptualization</role></contrib>
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<aff id="aff1"><label>1</label><institution>Department of Neuroscience, Institute of Sport and Sports Science, Albert-Ludwigs Universit&#x00E4;t</institution>, <city>Freiburg</city>, <country country="de">Germany</country></aff>
<aff id="aff2"><label>2</label><institution>BrainLinks-BrainTools Center, IMBIT, Albert-Ludwigs University of Freiburg</institution>, <city>Freiburg</city>, <country country="de">Germany</country></aff>
<author-notes>
<corresp id="cor1"><label>&#x002A;</label><bold>Correspondence:</bold> Natalie Mrachacz-Kersting <email xlink:href="mailto:natalie.mrachacz-kersting@sport.uni-freiburg.de">natalie.mrachacz-kersting@sport.uni-freiburg.de</email></corresp>
</author-notes>
<pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-03-11"><day>11</day><month>03</month><year>2026</year></pub-date>
<pub-date publication-format="electronic" date-type="collection"><year>2026</year></pub-date>
<volume>7</volume><elocation-id>1638091</elocation-id>
<history>
<date date-type="received"><day>30</day><month>05</month><year>2025</year></date>
<date date-type="rev-recd"><day>23</day><month>07</month><year>2025</year></date>
<date date-type="accepted"><day>11</day><month>02</month><year>2026</year></date>
</history>
<permissions>
<copyright-statement>&#x00A9; 2026 Hirsch and Mrachacz-Kersting.</copyright-statement>
<copyright-year>2026</copyright-year><copyright-holder>Hirsch and Mrachacz-Kersting</copyright-holder><license><ali:license_ref start_date="2026-03-11">https://creativecommons.org/licenses/by/4.0/</ali:license_ref><license-p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</license-p></license>
</permissions>
<abstract><sec><title>Objectives</title>
<p>To evaluate the effectiveness of augmented feedback (AF) in improving gait function in individuals with cerebral palsy (CP) and assess the strength of evidence across different gait parameters.</p>
</sec><sec><title>Eligibility criteria</title>
<p>We included peer-reviewed interventional studies involving children or adults with CP who received AF during gait training, with gait-related outcomes assessed.</p>
</sec><sec><title>Information sources</title>
<p>A systematic search was conducted in July 2025 across PubMed, Cochrane Library, IEEE Xplore, and PEDro database.</p>
</sec><sec><title>Risk of bias</title>
<p>Risk of bias was assessed using the Cochrane Risk of Bias tool for RCTs and MINORS criteria for other study designs.</p>
</sec><sec><title>Included studies</title>
<p>Of 477 screened records, 25 studies met inclusion criteria, comprising 612 total participants (409 intervention, 203 control). Studies included 13 single-session and 12 multi-session interventions.</p>
</sec><sec><title>Synthesis of results</title>
<p>Using systematic evidence synthesis, velocity improvements showed strong evidencial support for AF, while ankle kinematics demonstrated moderate to strong evidence. Visual feedback had the most consistent effects across parameters, particularly for kinematic outcomes. Most other gait parameters (step length, stride length, cadence) showed inconclusive evidence due to conflicting findings across studies of varying quality.</p>
</sec><sec><title>Limitations of evidence</title>
<p>High heterogeneity in protocols, outcome measures, and study quality (32&#x0025; high, 52&#x0025; moderate, 16&#x0025; low quality) prevented a meta-analysis. Limited long-term follow-up data (only 5 studies) restricts conclusions about sustained effects.</p>
</sec><sec><title>Interpretation</title>
<p>AF shows promise for enhancing gait velocity and ankle function in CP, particularly for spastic subtypes. However, evidence remains insufficient for widespread clinical adoption. Standardized protocols, larger sample sizes, and long-term follow-ups are essential for evidence-based implementation.</p>
</sec>
</abstract>
<kwd-group>
<kwd>cerebral palsy</kwd>
<kwd>locomotion</kwd>
<kwd>gait rehabilitation</kwd>
<kwd>augmented feedback</kwd>
<kwd>motor learning</kwd>
<kwd>pediatric motor disability</kwd>
</kwd-group><funding-group><funding-statement>The author(s) declared that financial support was not received for this work and/or its publication.</funding-statement></funding-group><counts>
<fig-count count="6"/>
<table-count count="3"/><equation-count count="0"/><ref-count count="58"/><page-count count="21"/><word-count count="0"/></counts><custom-meta-group><custom-meta><meta-name>section-at-acceptance</meta-name><meta-value>Rehabilitation in Neurological Conditions</meta-value></custom-meta></custom-meta-group>
</article-meta>
</front>
<body><sec id="s1" sec-type="intro"><title>Introduction</title>
<p>Cerebral palsy (CP) is a non-progressive neurological disorder caused by brain damage in the developing fetal or infant brain, affecting movement and posture (<xref ref-type="bibr" rid="B58">58</xref>). Motor impairments, particularly gait disturbances, are central features of CP, often accompanied by sensory, perceptual, cognitive, communication, and behavioral symptoms (<xref ref-type="bibr" rid="B59">59</xref>). CP is categorized into three subtypes&#x2014;spastic, dyskinetic, and ataxic&#x2014;based on the nature and extent of the brain lesion (<xref ref-type="bibr" rid="B1">1</xref>). These subtypes are further classified according to neurological involvement into unilateral (hemiplegia) and bilateral (diplegia or quadriplegia) presentations. Functional ability is assessed using the Gross Motor Function Classification System (GMFCS), which ranks motor abilities on a scale from levels I to V, with higher levels indicating more severe motor impairment (<xref ref-type="bibr" rid="B60">60</xref>).</p>
<p>As one of the leading causes of pediatric walking impairments, CP significantly limits mobility, restricting participation in daily activities and social engagement (<xref ref-type="bibr" rid="B61">61</xref>). Enhancing motor function through rehabilitation is crucial for improving the overall quality of life (<xref ref-type="bibr" rid="B2">2</xref>, <xref ref-type="bibr" rid="B3">3</xref>). Despite advances in treatment, many individuals with CP face considerable challenges with mobility: 43.7&#x0025; are not able to walk independently, where 11.1&#x0025; require assistive devices, and 32.6&#x0025; have minimal or no walking ability (<xref ref-type="bibr" rid="B62">62</xref>). There is a pressing need for novel rehabilitation approaches that target these specific motor deficits (<xref ref-type="bibr" rid="B63">63</xref>).</p>
<p>Augmented Feedback (AF), a technique that enhances the body&#x0027;s internal sensory system by providing external feedback to aid individuals in adjusting their movements (Moinuddin et al. 2021; W&#x00E4;lchli et al. 2016) has emerged as a promising tool for improving motor function and facilitating motor learning, particularly in rehabilitation settings (<xref ref-type="bibr" rid="B4">4</xref>). By providing real-time information about motor tasks, AF can enhance patient engagement and compliance during rehabilitation sessions (Merians et al. 2002). AF can be delivered through visual, auditory, or tactile stimuli, and is typically divided into two types: knowledge of results (KR), which provides feedback on the outcome of a movement, and knowledge of performance (KP), which focuses on the quality of the movement itself (<xref ref-type="bibr" rid="B5">5</xref>). Key factors in effective AF design include the specificity, timing, frequency, and level of guidance provided during the intervention.</p>
<p>Accumulating evidence suggests that external cueing exercises provided by AF may promote neuroplasticity, aiding motor recovery in patients with CP (Kleim and Jones 2008). Previous systematic reviews have explored various aspects of feedback and biofeedback in motor rehabilitation, including applications in CP. However, these were focused on upper limb motor skill learning (<xref ref-type="bibr" rid="B5">5</xref>), broad movement categories [Schoenmaker et al. 2022 (<xref ref-type="bibr" rid="B6">6</xref>);] or mixed neurological populations (<xref ref-type="bibr" rid="B7">7</xref>) limiting their relevance to gait-specific interventions in CP. While some reviews provide valuable theoretical frameworks or insights into specific feedback modalities, they often target other populations (<xref ref-type="bibr" rid="B8">8</xref>) or rely on studies involving healthy subjects and simple motor tasks (<xref ref-type="bibr" rid="B4">4</xref>). To date, no systematic review has focused exclusively on comparing different feedback modalities in gait rehabilitation for individuals with CP. This review addresses that critical gap by providing the targeted synthesis of evidence of AF for gait training in CP, allowing for a direct comparison of visual, auditory, and tactile feedback modalities within this specific clinical population.</p>
<p>Understanding how AF can influence the human gait cycle&#x2014;particularly in the context of CP&#x2014;presents a critical area for investigation. The human gait cycle consists of two main phases: the stance phase, when the foot is in contact with the ground, and the swing phase, when the foot moves forward. The stance phase comprises about 62&#x0025; of the gait cycle and includes five sub-phases: initial contact, loading response, mid-stance, push-off, and pre-swing (<xref ref-type="bibr" rid="B1">1</xref>, <xref ref-type="bibr" rid="B9">9</xref>). Gait impairments in CP vary depending on the clinical subtype. For instance, spastic hemiplegia often involves equinus, characterized by limited ankle dorsiflexion due to overactive plantar flexors or altered tissue properties (<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B10">10</xref>). Spastic diplegia is commonly associated with flexed knee gait, knee stiffness, in-toeing, and equinus, resulting from co-activation of antagonistic muscle groups (<xref ref-type="bibr" rid="B63">63</xref>, <xref ref-type="bibr" rid="B68">68</xref>). Dyskinetic CP, on the other hand, is characterized by involuntary movements that disrupt normal gait patterns, while ataxic CP involves a wide-based gait and exaggerated arm swings to compensate for balance deficits (<xref ref-type="bibr" rid="B1">1</xref>).</p>
<p>Across all CP subtypes, individuals tend to exhibit simplified motor control strategies, using fewer muscle synergies&#x2014;particularly at higher GMFCS levels. These limitations can significantly impact mobility and daily functioning (<xref ref-type="bibr" rid="B63">63</xref>, <xref ref-type="bibr" rid="B69">69</xref>). These gait abnormalities underscore the urgent need for effective rehabilitation interventions that can restore or improve walking abilities (<xref ref-type="bibr" rid="B70">70</xref>, <xref ref-type="bibr" rid="B71">71</xref>).</p>
<p>This systematic review aims to evaluate the effectiveness of different augmented feedback modalities, including visual, auditory, and tactile, for gait rehabilitation in individuals with CP. By focusing exclusively on this population and motor task, the review provides a focused synthesis of outcomes, informs future research and practice, and addresses a key gap in the existing literature.</p>
</sec>
<sec id="s2" sec-type="methods"><title>Materials and methods</title>
<p>The PRISMA guidelines (<xref ref-type="bibr" rid="B11">11</xref>) were strictly followed and the PRISMA checklist is provided in the <xref ref-type="sec" rid="s10">Supplementary Material</xref>. A comprehensive literature search was conducted across multiple databases, including Cochrane Library, PubMed, IEEE Xplore and PEDro Library, to identify relevant literature. The search was completed as of July 11, 2025. Both manual and electronic searches were performed to ensure a thorough inclusion of relevant studies. The full search strings for Cochrane Library, IEEE Xplore and PEDro Library are available in the <xref ref-type="sec" rid="s10">Supplementary Material</xref>. The search term used in the PubMed search was as follows:</p>
<p>(cerebral palsy OR CP OR &#x201C;Cerebral Palsy&#x0022;[Mesh]) AND (((augmented OR extrinsic OR external OR verbal OR visual OR video OR auditory OR haptic OR tactile OR sensory OR robot&#x002A; OR multi-modal OR multimodal OR bio OR neuro OR vibrotactile) AND feedback) OR neurofeedback OR biofeedback OR visual augmented feedback OR audio augmented feedback OR multi-modal augmented feedback OR knowledge of performance OR knowledge of result&#x002A; OR enhanced feedback OR feedback strateg&#x002A; OR &#x201C;Feedback, Sensory&#x0022;[Mesh] OR &#x201C;Feedback, Physiological&#x0022;[Mesh] OR &#x201C;Feedback&#x0022;[Mesh] OR &#x201C;Neurofeedback&#x0022;[Mesh]) AND (walk&#x002A; speed OR gait speed OR gait velocity OR walk velocity OR Step length OR Gait width OR mobility test OR spatiotemporal OR walk&#x002A; test OR up and go OR Berg Balance Scale OR Physiological cost index OR Walking handicap scale OR (Functional Ambulation AND (Index OR Score)) OR step frequency OR cadence OR &#x201C;Walking Speed&#x0022;[Mesh] OR &#x201C;Walk Test&#x0022;[Mesh] OR &#x201C;Gait Analysis&#x0022;[Mesh] OR &#x201C;Gait&#x0022;[Mesh]).</p>
<p>A total of 477 results were obtained. After removing duplicates (<italic>n</italic>&#x2009;&#x003D;&#x2009;53) and pre-registered clinical trials (<italic>n</italic>&#x2009;&#x003D;&#x2009;39), 385 studies were eligible for screening. Additionally google scholar was searched for grey literature and reference lists of relevant articles were checked to ensure the identification of relevant articles that had been missed by the electronic search. In this manually performed search twelve articles were additionally identified. The metrics are shown in the PRISMA-Flowchart in <xref ref-type="fig" rid="F1">Figure&#x00A0;1</xref>.</p>
<fig id="F1" position="float"><label>Figure&#x00A0;1</label>
<caption><p>PRISMA flowchart of the conducted search.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fresc-07-1638091-g001.tif"><alt-text content-type="machine-generated">PRISMA flow diagram illustrating study selection: 477 records identified from databases, 81 from other sources, duplicates and ineligible records removed, 385 screened, 41 assessed for eligibility, 25 studies included in the final review with reasons for exclusion detailed at each stage.</alt-text>
</graphic>
</fig>
<sec id="s2a"><title>Study selection</title>
<p>The study selection was performed with the Software ASReview Lab, a machine learning-based software for systematic reviews (<xref ref-type="bibr" rid="B12">12</xref>). After uploading metadata (titles and abstracts), an initial manual screening of 10&#x0025; of the studies (<italic>n</italic>&#x2009;&#x003D;&#x2009;39) was conducted to train the software&#x0027;s AI algorithm. Two researchers independently performed this initial screening to ensure reliability in the training set. The remaining 385 studies were screened using this trained algorithm. Of the 346 papers reviewed, 42 were labeled as relevant for further analysis.</p>
<p>The use of ASReview allowed for a more efficient screening process while maintaining transparency and traceability of inclusion decisions (<xref ref-type="bibr" rid="B12">12</xref>). However, machine learning-based screening relies heavily on the quality of the initial training data and may risk overlooking relevant studies if the training set is not representative. To avoid this, independent screening was used for the initial training, and the final selection was verified by two researchers to ensure consistency.</p>
<p>Studies were included if they (1) involved patients diagnosed with cerebral palsy (CP) or comparisons between CP patients and healthy controls, (2) the intervention involved a task requiring participants to walk during the intervention and assessed the effects of augmented feedback on gait rehabilitation, (3) a comparisons was made between CP patients and healthy controls, different rehabilitation methods, or through pre- and post-intervention assessments within the same group, (4) the outcomes included quantitative measures related to gait performance, such as spatiotemporal, kinematic, kinetic, and electromyographic parameters, (5) the original research was original and peer-reviewed, was (6) conducted on humans, and lastly (7) the articles had to be published in English or German.</p>
<p>Studies were excluded if they (1) involved etiologies other than CP, (2) used interventions based on mirror therapy, electrical stimulation, or exoskeletons (unless the feedback was analyzed separately) and (3) they were in the format of commentaries, expert reports, pre-registered trials, reviews, meta-analyses, and non-peer-reviewed publications.</p>
<p>Studies involving robotic or electromechanical exoskeletons were excluded to isolate the effects of augmented sensory feedback (e.g., auditory, visual, or tactile) delivered without mechanical assistance. The aim was to focus on feedback-driven motor learning rather than assistive gait devices.</p>
<p>Given that only a few high-quality randomized controlled trials were available on this topic on augmented feedback for gait rehabilitation in cerebral palsy, this review intentionally included a range of study designs. All included studies assessed gait parameters, enabling a degree of comparability despite methodological differences. With this procedure the study aimed to provide a broad overview of current evidence, including both experimental and preliminary studies. While study designs vary, the goal is to offer an informative synthesis to inform future research and clinical practice. Due to the heterogeneity in study designs, intervention protocols, and outcome measures, a quantitative meta-analysis was not feasible. Instead, a qualitative synthesis was conducted to summarize the levels of evidence, identify trends, and highlight gaps in the literature.</p>
<p>Full-text screening was conducted on 41 studies. Studies were excluded if they were: Non-peer-reviewed publications (<italic>n</italic>&#x2009;&#x003D;&#x2009;5), no gait task in the intervention (<italic>n</italic>&#x2009;&#x003D;&#x2009;12), inclusion of other patient groups (<italic>n</italic>&#x2009;&#x003D;&#x2009;3), case studies (<italic>n</italic>&#x2009;&#x003D;&#x2009;4) and focus on long-term follow-up only (<italic>n</italic>&#x2009;&#x003D;&#x2009;1). Fourteen studies met the inclusion criteria. Two papers with similar study designs but different outcome measures were also included (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B14">14</xref>). A manual literature search identified 12 potentially relevant studies, five of those were excluded, leaving 7 studies via citation searching. In total, 25 studies were included in this systematic review.</p>
</sec>
<sec id="s2b"><title>Data extraction and study quality</title>
<p>Data from the studies were extracted using a pre-developed electronic data sheet. The extracted information included study design, participant demographics (e.g., sex, age, weight, CP type, GMFCS level), feedback protocol characteristics, measurement tools, and reported outcomes. Gait performance measures, such as spatiotemporal, kinematic, and kinetic parameters, were extracted. One reviewer performed the data extraction, which was then reviewed and verified by a second researcher to ensure completeness and accuracy. Additionally, data for assessing the quality of the studies was first assessed by one reviewer and subsequently discussed with a second reviewer to reach agreement for each study.</p>
<p>The methodological quality of non-randomized studies was assessed using the MINORS tool (<xref ref-type="bibr" rid="B15">15</xref>). This tool evaluates 12 criteria, with a maximum score of 16 for non-comparative studies and 24 for comparative studies. Higher scores indicate stronger methodological quality. For randomized controlled trials (RCTs), the Revised Cochrane Risk-of-Bias Tool 2 (RoB 2) was used (<xref ref-type="bibr" rid="B16">16</xref>). RoB 2 assesses bias in randomization, adherence to interventions, outcome measurement, and data reporting. Studies were categorized as low, unclear, or high risk of bias, with results presented in a risk-of-bias figure. Both tools provided insights into the strengths and limitations of the studies, contributing to a comprehensive analysis of the reliability of the findings in this systematic review.</p>
</sec>
<sec id="s2c"><title>Level of evidence synthesis</title>
<p>Building upon the heterogeneity of study designs and outcomes outlined in <xref ref-type="sec" rid="s2b">Section 2.2</xref>, a quantitative meta-analysis was not feasible. Instead, a level of evidence synthesis was performed to assess the consistency and reliability of findings across studies. For each outcome parameter, the direction of effect reported in the included studies was examined. When 75&#x0025; or more of the studies analyzing a specific parameter demonstrated effects in the same direction, the findings were classified as consistent. The overall level of evidence was determined based on both the consistency of findings and the methodological quality of the contributing studies, using the following criteria: evidence was categorized as strong when consistent findings (&#x2265;75&#x0025;) were observed in two or more high-quality studies. Evidence was considered moderate when consistent findings were present in at least 67&#x0025; of high-quality studies. Limited evidence was assigned when consistent effects were found in a single high-quality study or in one or more low- or moderate-quality studies. Inconclusive evidence was assigned when results were inconsistent (i.e., pointed in different directions), regardless of study quality. In cases where multiple high-quality studies were available, only those high-quality studies were considered in determining the level of evidence.</p>
</sec>
</sec>
<sec id="s3" sec-type="results"><title>Results</title>
<p>A total of 25 out of 397 studies met the inclusion criteria. The results of these studies are presented in the following sections.</p>
<sec id="s3a"><title>Participants</title>
<p>A total of 612 participants were included across all studies, with 409 participating in intervention groups and 203 in control groups. Within the control groups, 121 participants were typically developing (TD). Eleven studies did not include a control group (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B17">17</xref>&#x2013;<xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B72">72</xref>). Participants&#x0027; ages ranged from 3 to 65 years, with a mean age of 11.56&#x2009;&#x00B1;&#x2009;5.45years. The sex distribution in the study groups was 202 males to 143 females, though five studies did not report the sex of their participants. Eight studies included adults (<xref ref-type="bibr" rid="B19">19</xref>, <xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B25">25</xref>&#x2013;<xref ref-type="bibr" rid="B29">29</xref>). The majority of participants had spastic cerebral palsy (CP), with 352 cases, including spastic hemiplegia, diplegia, and quadriplegia. Most studies used GMFCS I-III as an inclusion criterion, with 71 participants classified as GMFCS I, 92 as GMFCS II, and 11 as GMFCS III. Eleven studies did not report GMFCS levels (<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B18">18</xref>, <xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B27">27</xref>&#x2013;<xref ref-type="bibr" rid="B33">33</xref>). More detailed information on participant demographics is provided in <xref ref-type="table" rid="T1">Tables&#x00A0;1</xref> and <xref ref-type="table" rid="T2">2</xref>.</p>
<table-wrap id="T1" position="float"><label>Table&#x00A0;1</label>
<caption><p>Extracted details of the included single-session studies.</p></caption>
<table>
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="right"/>
<col align="right"/>
<col align="left"/>
<col align="center"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Reference</th>
<th valign="top" align="center">Study design</th>
<th valign="top" align="center">N (ig)</th>
<th valign="top" align="center">M:f</th>
<th valign="top" align="center">Cp characteristics</th>
<th valign="top" align="center">Age</th>
<th valign="top" align="center">Control group</th>
<th valign="top" align="center">Intervention/gait task</th>
<th valign="top" align="center">Frequency&#x002B;duration</th>
<th valign="top" align="center">Comparison/control condition</th>
<th valign="top" align="center">Outcome measure</th>
<th valign="top" align="center">Feedback provided</th>
<th valign="top" align="center">Significant outcome parameters</th>
<th valign="top" align="center">Study quality</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B13">13</xref>)(1)</td>
<td valign="top" align="left">Repeated measures design</td>
<td valign="top" align="right">25</td>
<td valign="top" align="right">15:07</td>
<td valign="top" align="left">Spastic CP (hemiplegia, diplegia); GMFCS I: 10, II: 12</td>
<td valign="top" align="center">10.5&#x2009;&#x00B1;&#x2009;3.1</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">Treadmill walking with visual feedback comparing knee extension and ankle power through bar graph or avatar</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">&#x00A0;VR scene without Feedback</td>
<td valign="top" align="left">Spatiotemporal paramters; kinematic parameters (joing angles, joint work)</td>
<td valign="top" align="left">KP (v), concurrent, Continous, Descriptive</td>
<td valign="top" align="left">step length &#x2191;<break/>step width &#x2193;<break/>ankle power generation at push-off &#x2191;<break/>knee RoM &#x2191;<break/>Max knee ext (stance) &#x2191;<break/>Max knee ext Initial Contact &#x2191;<break/>Hip RoM &#x2191;<break/>hip abduction (swing) &#x2191;<break/>Max hip ext &#x2191;</td>
<td valign="top" align="left">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B34">34</xref>)</td>
<td valign="top" align="left">Cross-sectional crossover trial with a repeated measures design</td>
<td valign="top" align="right">25</td>
<td valign="top" align="right">11:14</td>
<td valign="top" align="left">Spastic CP (hemiplegia, diplegia, and quadriplegia); GMFCS I:15:; II:10</td>
<td valign="top" align="center">14.7&#x2009;&#x00B1;&#x2009;1.6</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">30&#x2005;m walking with visual feedback on walking speed through different cues from a headset</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">&#x00A0;walking without feedback (30&#x2005;m)</td>
<td valign="top" align="left">Mean speed, percentage of time spent above or around target speed&#x2009;&#x002B;&#x2009;time to reach target speed</td>
<td valign="top" align="left">KP (v), concurrent, Continous, Pescriptive</td>
<td valign="top" align="left">velocity &#x2191;<break/>time above target speed &#x2191;<break/>time to reach the target speed &#x2193;</td>
<td valign="top" align="left">Low</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B14">14</xref>) (2)</td>
<td valign="top" align="left">Repeated measures design</td>
<td valign="top" align="right">25</td>
<td valign="top" align="right">16:09</td>
<td valign="top" align="left">Spastic CP; GMFCS I: 10, II: 12</td>
<td valign="top" align="center">10.4&#x2009;&#x00B1;&#x2009;3.1</td>
<td valign="top" align="left">27 TD</td>
<td valign="top" align="left">Treadmill walking with visual feedback comparing knee extension and ankle power through bar graph or avatar</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">&#x00A0;TD walking without feedback</td>
<td valign="top" align="left">Spatiotemporal paramters; kinematic parameters (joing angles, joint work)</td>
<td valign="top" align="left">KP (v), concurrent, Continous, Descriptive</td>
<td valign="top" align="left">number of synergies required to explain at least 90&#x0025; of muscle activation &#x2191;<break/>change in measures of Total variance accounted for during trials &#x2192;</td>
<td valign="top" align="left">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B35">35</xref>)</td>
<td valign="top" align="left">Within-subject comparative study (repeated measures design)</td>
<td valign="top" align="right">16</td>
<td valign="top" align="right">/</td>
<td valign="top" align="left">Spastic CP; GMFCS I-III</td>
<td valign="top" align="center">11.3&#x2009;&#x00B1;&#x2009;3.4y</td>
<td valign="top" align="left">11 TD</td>
<td valign="top" align="left">Treadmill walking comparing visual feedback on knee extension and hip Extension</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">&#x00A0;TD walking without feedback</td>
<td valign="top" align="left">&#x00A0;Spatiotemporal paramters; kinematic parameters (joing angles, gait profile score (GPS)</td>
<td valign="top" align="left">KP (v), concurrent, Continous, Descriptive</td>
<td valign="top" align="left">stride length &#x2191;<break/>swing time &#x2191;<break/>Dorsiflexion (late stance) &#x2191;<break/>Max knee ext &#x2191;<break/>Max hip ext &#x2191;<break/>Trunk&#x2009;&#x002B;&#x2009;Pelvis RoM &#x2191;</td>
<td valign="top" align="left">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B20">20</xref>)</td>
<td valign="top" align="left">&#x00A0;Feasibility study with a randomized crossover design</td>
<td valign="top" align="right">12</td>
<td valign="top" align="right">09:03</td>
<td valign="top" align="left">CP; GMFCS I-III (I:5;II:5;III: 2)</td>
<td valign="top" align="center">18.91&#x2009;&#x00B1;&#x2009;8.4y</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">Treadmill walking with: only visual feedback on plantar preasure in virtual enviroment, only walking with exsceleton; and the combination</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">Incline walking without feedback/ assistance</td>
<td valign="top" align="left">ankle, knee, and hip mechanics&#x2009;&#x002B;&#x2009;plantar flexor and knee extensor EMG activity</td>
<td valign="top" align="left">KP (v), concurrent, Continous, Pescriptive</td>
<td valign="top" align="left">peak ankle momentum &#x2191;<break/>mean positive ankle power (stance) &#x2191;<break/>max knee extension &#x2191;<break/>peak&#x2009;&#x002B;&#x2009;intrgrated SOL EMG &#x2191;<break/>peak&#x002B;intrgrated Gastro EMG &#x2191;<break/>peak&#x002B;intrgrated VL EMG &#x2191;</td>
<td valign="top" align="left">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B36">36</xref>)</td>
<td valign="top" align="left">observational cross-sectional feasibility study</td>
<td valign="top" align="right">18</td>
<td valign="top" align="right">10:08</td>
<td valign="top" align="left">Spastic CP (hemiplegia, diplegia); GMFCS I: 9, II: 9</td>
<td valign="top" align="center">10.5&#x2009;&#x00B1;&#x2009;2.9</td>
<td valign="top" align="left">12 TD</td>
<td valign="top" align="left">Treadmill walking with visual feedback on SOL/GM EMG activity through controlling a monkey in virtual enviroment</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">&#x00A0;TD walking in gaming enviroment without Feedback</td>
<td valign="top" align="left">EMG activity; Joint angles</td>
<td valign="top" align="left">KP (v), concurrent, Continous, Descriptive</td>
<td valign="top" align="left">peak ankle power (push-off) &#x2191;<break/>max knee extension &#x2191;<break/>muscle activity Triceps Surae (early stance) &#x2193;</td>
<td valign="top" align="left">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B24">24</xref>)</td>
<td valign="top" align="left">&#x00A0;Single-group repeated measures design</td>
<td valign="top" align="right">13</td>
<td valign="top" align="right">06:07</td>
<td valign="top" align="left">Spastic CP (diaplegia); GMFCS I&#x2009;&#x003D;&#x2009;9; II&#x2009;&#x003D;&#x2009;4</td>
<td valign="top" align="center">6&#x2009;&#x00B1;&#x2009;2.08</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">10&#x2005;m walking with auditive feedback on Dynamic foot pressure index through sound of negative result</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">walking without feedback/ instructions</td>
<td valign="top" align="left">dynamic foot pressure index</td>
<td valign="top" align="left">KP (a), concurrent, Continous, Descriptive</td>
<td valign="top" align="left"><break/>dynamic foot pressure index &#x2191;</td>
<td valign="top" align="left">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B26">26</xref>)</td>
<td valign="top" align="left">Experimental study with multiple intervention arms and control groups</td>
<td valign="top" align="right">20</td>
<td valign="top" align="right">V: 03:07; A: 04:07</td>
<td valign="top" align="left">CP</td>
<td valign="top" align="center">V: 11.1&#x2009;&#x00B1;&#x2009;6.24; A: 13.3&#x2009;&#x00B1;&#x2009;5.9</td>
<td valign="top" align="left">V: 7; A; 8 TD</td>
<td valign="top" align="left">10&#x2005;m walking with visual (v) and auditory (a) feedback on through step length (a)&#x2009;&#x002B;&#x2009;motion of the patient (a) through dynamic traverse lines (v, VR)&#x2009;&#x002B;&#x2009;clicking sound (a)</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">pre-post (20&#x2005;min); TD also underwent a/v feedback programm</td>
<td valign="top" align="left">Spatiotemporal paramters</td>
<td valign="top" align="left">KP (a vs. v), concurrent, Continous, Descriptive</td>
<td valign="top" align="left"><break/><break/>stride length &#x2191;<break/>velocity &#x2191;</td>
<td valign="top" align="left">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B19">19</xref>)</td>
<td valign="top" align="left">Validation study with a repeated measures crossover design</td>
<td valign="top" align="right">8</td>
<td valign="top" align="right">07:01</td>
<td valign="top" align="left">Spastic CP(hemiplegia; diplegia); GMFCS I:2; II:4; III:2</td>
<td valign="top" align="center">14.38&#x2009;&#x00B1;&#x2009;2.34</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">treadmill walking with auditive (a)&#x2009;&#x002B;&#x2009;visual (v) Feedback on SOL EMG activity and plantar presure through a bar graph (v)&#x2009;&#x002B;&#x2009;sound signal (a)</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">&#x00A0;walking without feedback</td>
<td valign="top" align="left">Kninematic paramters (joint angles), EMG anctivity</td>
<td valign="top" align="left">KP (v)/ KR (a), concurrent, Continous, Pescriptive</td>
<td valign="top" align="left">mean SOL activation &#x2191;<break/>mean&#x002B;peak Gastro activation &#x2191;<break/>Ankle co-contraction index &#x2191;</td>
<td valign="top" align="left">High</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B30">30</xref>)</td>
<td valign="top" align="left">cross sectional study</td>
<td valign="top" align="right">12</td>
<td valign="top" align="right">09:03</td>
<td valign="top" align="left">CP type N/A; GMFCS I &#x0026;II</td>
<td valign="top" align="center">11.4&#x2009;&#x00B1;&#x2009;3.6</td>
<td valign="top" align="left">age matched healthy controls (<italic>n</italic>&#x2009;&#x003D;&#x2009;12)</td>
<td valign="top" align="left">Participants walked a 10-meter path with a wearable sensor providing real-time tactile vibration feedback when trunk sway exceeded set limits, aiming to improve trunk stability and gait control.</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">walking without tactile feedback within group; Age-matched typically developed children</td>
<td valign="top" align="left">lower extremity movement trajectories and ROM; Spatial-temporal parameters</td>
<td valign="top" align="left">KP (t), concurrent, continuous, descriptive</td>
<td valign="top" align="left">Stance phase (&#x0025;) &#x2193;: 73.91&#x0025; &#x2192; 63.53&#x0025;<break/>Step width &#x2193;: 0.20&#x2005;m &#x2192; 0.18&#x2005;m<break/>Step time &#x2193;: 1.55 s &#x2192; 0.73 s<break/>Cadence &#x2191;: 59.25 &#x2192; 63.63 steps/min<break/>Walking speed &#x2191;: 0.52 &#x2192; 0.61&#x2005;m/s<break/>Pelvic tilt &#x2193;: 4.2&#x00B0; &#x2192; 2.9&#x00B0;; obliquity &#x2193;: 13.1&#x00B0; &#x2192; 9.2&#x00B0;; rotation &#x2193;: 17.5&#x00B0; &#x2192; 11.2&#x00B0;<break/>Ankle plantarflexion at initial contact &#x2193;<break/>Ankle dorsiflexion (stance &#x0026; swing) &#x2191;<break/>Ankle ROM &#x2191;: 23.5&#x00B0; &#x2192; 34.8&#x00B0;<break/>Knee ROM &#x2191;: 31.7&#x00B0; &#x2192; 36.7&#x00B0;<break/>Hip ROM &#x2191;: 31.7&#x00B0; &#x2192; 36.7&#x00B0;</td>
<td valign="top" align="left">High</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B21">21</xref>)</td>
<td valign="top" align="left">a repeated-measures analysis</td>
<td valign="top" align="right">12</td>
<td valign="top" align="right">12:00</td>
<td valign="top" align="left">spastic quadriplegia; GMFCS I</td>
<td valign="top" align="center">13&#x2009;&#x00B1;&#x2009;3.5</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">Participants walked along an 8-meter platform guided by rhythmic auditory stimulation delivered via loudspeakers, using 2-, 4-, and 6-beat rhythm patterns to improve gait timing and coordination.</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">pre&#x2013;post test design</td>
<td valign="top" align="left">Time and distance gait parameters including walking velocity, cadence, stride/step length, step width, step/stride time, single and double support (&#x0025; and time), double step length, opposite foot lift (&#x0025;), and limp index</td>
<td valign="top" align="left">KP (a), concurrent, continuous, prescriptive</td>
<td valign="top" align="left">velocity (6-beat&#x2191;, 4,2-beat&#x2193;)<break/>cadence &#x2193; (6,4,2-beat)<break/>step length &#x2193; (4,2-beat)<break/>Double support time &#x2191; (6,4-beat)<break/>opposite foot lift &#x2193; (6,4,2-beat)<break/>double-step length &#x2193; (4,2-beat)<break/>&#x00A0;Double support (6-beat&#x2193;, 4,2-beat&#x2191;)<break/>Single support (6,4-beat&#x2193;, 2-beat&#x2191;)<break/>&#x00A0;double support time &#x2191; (6-beat, 4-beat)<break/>stride length &#x2193; (2-beat)<break/>Limp index &#x2193; (6,4,2-beat)<break/>Step width &#x2191; (6,4-beat)</td>
<td valign="top" align="left">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B27">27</xref>)</td>
<td valign="top" align="left">a repeated-measures analysis</td>
<td valign="top" align="right">14</td>
<td valign="top" align="right">09:05</td>
<td valign="top" align="left">bilateral spasticity; GMFCS I -III</td>
<td valign="top" align="center">25.64&#x2009;&#x00B1;&#x2009;7.31</td>
<td valign="top" align="left">helathy controls (<italic>n</italic>&#x2009;&#x003D;&#x2009;30)</td>
<td valign="top" align="left">Walking was performed over 10 meters with rhythmic auditory stimulation combining a metronome beat matched to individual cadence and live keyboard-played simple chords to promote immediate gait improvements.</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">epeated-measures analysis with/ without RAS; Comparison healthy controls</td>
<td valign="top" align="left">Temporospatial parameters (cadence, velocity, stride/step length and time, single/double limb support, stance and swing phase, side-to-side asymmetry); kinematic angles of pelvis, hip, knee, ankle, and foot across sagittal, coronal, and transverse planes; Gait Deviation Index (GDI).</td>
<td valign="top" align="left">KP (a), concurrent, continuous, descriptive</td>
<td valign="top" align="left">pelvic anterior tilt &#x2193;<break/>hip flexion &#x2193;<break/>Gait Deviation Index (GDI) &#x2191;<break/>step length asymmetry &#x2193; (household ambulators)</td>
<td valign="top" align="left">High</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B23">23</xref>)</td>
<td valign="top" align="left">cross-sectional design</td>
<td valign="top" align="right">10</td>
<td valign="top" align="right">07:03</td>
<td valign="top" align="left">hemiplegic CP; GMFCS I: 9, II: 1</td>
<td valign="top" align="center">4.98&#x2009;&#x00B1;&#x2009;0.8</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">The intervention involved children walking across a GAITRite system walkway while observing a virtual reality screen that displayed modulated optic flow speed (slow, medium, fast). The virtual environment mimicked walking in a park.</td>
<td valign="top" align="left">single session</td>
<td valign="top" align="left">3 optic flow speed conditions:<break/>&#x00A0;Slow (0.25&#x00D7; the normal speed)<break/>&#x00A0;Normal speed<break/>Fast (2&#x00D7; the normal speed)</td>
<td valign="top" align="left">study assessed spatiotemporal gait parameters using a GAITRite system, including walking velocity, cadence, stride length, step length, normalized step length, single and double support time, and base of support.</td>
<td valign="top" align="left">KP (v), concurrent, Continous, Pescriptive</td>
<td valign="top" align="left">fast optic flow:<break/>walking velocity &#x2191;<break/>cadence &#x2191;<break/>normalized step length &#x2191;<break/>base of support &#x2191;<break/>single support cycle &#x2191;<break/><break/>slow optic flow:<break/>walking velocity &#x2193;<break/>cadence &#x2193;<break/>normalized step length &#x2193;<break/>base of support &#x2193;<break/>single support cycle &#x2193;</td>
<td valign="top" align="left">High</td>
</tr>
</tbody>
</table>
</table-wrap>
<table-wrap id="T2" position="float"><label>Table&#x00A0;2</label>
<caption><p>Extracted details of the included multi-session studies.</p></caption>
<table>
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="right"/>
<col align="right"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Reference</th>
<th valign="top" align="center">Study design</th>
<th valign="top" align="center">n (IG)</th>
<th valign="top" align="center">M:F</th>
<th valign="top" align="center">CP characteristics</th>
<th valign="top" align="center">Age</th>
<th valign="top" align="center">Control group</th>
<th valign="top" align="center">Intervention/gait task</th>
<th valign="top" align="center">Frequency&#x002B;Duration</th>
<th valign="top" align="center">Comparison/Control Condition</th>
<th valign="top" align="center">Outcome Measure</th>
<th valign="top" align="center">Feedback provided</th>
<th valign="top" align="center">significant outcome parameters</th>
<th valign="top" align="center">Study Quality</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B33">33</xref>)</td>
<td valign="top" align="left">RCT</td>
<td valign="top" align="right">30</td>
<td valign="top" align="right">15:15</td>
<td valign="top" align="left">Spastic CP (hemiplegia); GMFCS I, II</td>
<td valign="top" align="left">6&#x2013;10y</td>
<td valign="top" align="left">15 children with spastic CP</td>
<td valign="top" align="left">walking with auditory Feedback on cadence on steps through rythmic auditory beats</td>
<td valign="top" align="left">Intervention</td>
<td valign="top" align="left">pre-post (4 months);traditional rehabilitation programm</td>
<td valign="top" align="left">Spatiotemporal paramters</td>
<td valign="top" align="left">KP (a), concurrent, Continous, Perscriptive</td>
<td valign="top" align="left">step length asymmetry &#x2193;<break/>stride length asymmetry &#x2193;<break/>stance time asymmetry &#x2193;<break/>swing time asymmetry &#x2193;</td>
<td valign="top" align="left">Low</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B18">18</xref>)</td>
<td valign="top" align="left">&#x00A0;Pre-post intervention study (single-group pre-post design)</td>
<td valign="top" align="right">8</td>
<td valign="top" align="right">/</td>
<td valign="top" align="left">Spastic/ mixed CP</td>
<td valign="top" align="left">6&#x2009;&#x00B1;&#x2009;1.66y</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">walking with auditory Feedback on heel preasure through buzzing sound</td>
<td valign="top" align="left">Intervention (4 months)</td>
<td valign="top" align="left">pre-post (3 months-1y); walking without feedback</td>
<td valign="top" align="left">&#x00A0;passive ankle dorsiflexion, number of seconds of heel contact</td>
<td valign="top" align="left">KP (a), concurrent, Continous, Descriptive</td>
<td valign="top" align="left">the total duration of heel down &#x2191;<break/>total number of heel strikes &#x2191;<break/>dorsiflexion with the knee extended (IC) &#x2191;</td>
<td valign="top" align="left">Low</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B32">32</xref>)</td>
<td valign="top" align="left">RCT</td>
<td valign="top" align="right">30</td>
<td valign="top" align="right">17:13</td>
<td valign="top" align="left">Spastic CP&#x2009;&#x002B;&#x2009;E19(hemiplegia)</td>
<td valign="top" align="left">&#x00A0;7.05&#x2009;&#x00B1;&#x2009;0.78</td>
<td valign="top" align="left">15 children with spastic CP</td>
<td valign="top" align="left">different walking sytyles with auditory feedback on step length and walking speed through rythm&#x2009;&#x002B;&#x2009;speed of music</td>
<td valign="top" align="left">Intervention (8 weeks, 5 sessions/ week)</td>
<td valign="top" align="left">pre-post (3months); Control group recieved traditional gait training programme</td>
<td valign="top" align="left">Spatiotemporal paramters</td>
<td valign="top" align="left">KP (a),concurrent, Continous, Descriptive</td>
<td valign="top" align="left">velocity &#x2191;<break/>stride length &#x2191;<break/>cadence &#x2193;</td>
<td valign="top" align="left">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B37">37</xref>)</td>
<td valign="top" align="left">RCT</td>
<td valign="top" align="right">30</td>
<td valign="top" align="right">/</td>
<td valign="top" align="left">Spastic CP(diaplegia); GMFCS II</td>
<td valign="top" align="left">5.23&#x2009;&#x00B1;&#x2009;0.52</td>
<td valign="top" align="left">15 children with spastic CP</td>
<td valign="top" align="left">waking with visual feedback on plantar preasure through visualization of seven pressure areas of the foot</td>
<td valign="top" align="left">Intervention (24 sessions)</td>
<td valign="top" align="left">pre-post (2 months); therapeutic exercise program for 1&#x2005;h 30&#x2005;min walking without feedback</td>
<td valign="top" align="left">Spatiotemporal paramters</td>
<td valign="top" align="left">KP (v), concurrent, Continous, Descriptive</td>
<td valign="top" align="left">step length &#x2191;<break/>step width &#x2193;<break/>cadence &#x2191;<break/>velocity &#x2191;</td>
<td valign="top" align="left">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B17">17</xref>)</td>
<td valign="top" align="left">&#x00A0;Two-period crossover design</td>
<td valign="top" align="right">7</td>
<td valign="top" align="right">04:03</td>
<td valign="top" align="left">Spastic CP (hemiplegia)</td>
<td valign="top" align="left">10.57&#x2009;&#x00B1;&#x2009;2.56</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">walking with auditive (a)&#x2009;&#x002B;&#x2009;visual (v) Feedback on Triceps surae EMG activity through a dynamic line (v) and sound signal (a)</td>
<td valign="top" align="left">Intervention (8 sessions)</td>
<td valign="top" align="left">pre-post; follow-up (1w); Physical therapy (2 groups, both did intervention&#x002B;control condition)</td>
<td valign="top" align="left">Spatiotemporal paramters; kinematic parameters (joing angles, joint work)</td>
<td valign="top" align="left">KP&#x2009;&#x002B;&#x2009;KR (v); KR (a), V:Concurrent&#x002B;Terminal; A: Terminal After every step; Continous, v: Perscriptive; a: Descriptive: correct aspects of performence</td>
<td valign="top" align="left">Peak power generation at the ankle (push-off) &#x2191;</td>
<td valign="top" align="left">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B28">28</xref>)</td>
<td valign="top" align="left">Randomized controlled trial repeated-measures analysis comparing pretreatment and posttreatment tests</td>
<td valign="top" align="right">15</td>
<td valign="top" align="right">10:05</td>
<td valign="top" align="left">Bilateral spasticity/GMFCS N/A</td>
<td valign="top" align="left">27.3&#x2009;&#x00B1;&#x2009;2.4</td>
<td valign="top" align="left">neurodevelopmental treatment (NDT) (<italic>n</italic>&#x2009;&#x003D;&#x2009;13)</td>
<td valign="top" align="left">Participants received 30-minute gait training sessions, three times weekly, comparing rhythmic auditory stimulation with metronome and live keyboard cues versus traditional neurodevelopmental Bobath therapy for gait enhancement.</td>
<td valign="top" align="left">Intervention (9 sessions)</td>
<td valign="top" align="left">pre&#x2013;post test design; Rhythmic Auditory Stimulation (RAS) group; Neurodevelopmental Treatment (NDT/Bobath) group</td>
<td valign="top" align="left">Temporal gait parameters (cadence, velocity, stride/step length and time, stance and swing phase); kinematic joint angles (pelvis, hip, knee, ankle, foot); Gait Deviation Index (GDI)</td>
<td valign="top" align="left">KP (a), concurrent, continuous, descriptive</td>
<td valign="top" align="left">cadence &#x2191;<break/>walking velocity &#x2191;<break/>stride length &#x2191;<break/>step length &#x2191;<break/>stride time &#x2193;<break/>step time &#x2193;<break/>pelvic anterior tilt &#x2193;<break/>hip flexion (minimal) &#x2193;<break/>Gait Deviation Index (GDI) &#x2191;<break/>swing phase &#x2191;</td>
<td valign="top" align="left">High</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B38">38</xref>)</td>
<td valign="top" align="left">pre-post treatment experimental desig; pilot study</td>
<td valign="top" align="right">11 (9 included in analysis)</td>
<td valign="top" align="right">04:05</td>
<td valign="top" align="left">spastic CP (Hemiplegia:4 Diplegia.3 Quadriplegia:2); GMFCS Levels: I: 2; II: 4; III: 3</td>
<td valign="top" align="left">6.89&#x2009;&#x00B1;&#x2009;2.98</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">Children walked on a 14-meter walkway receiving rhythmic auditory stimulation via metronome or embedded music beats at normal and increased tempos, with rest intervals and pre/post cueing walks to measure carry-over effects.</td>
<td valign="top" align="left">Intervention (3 sessions)</td>
<td valign="top" align="left">walking without cueing; 2 different cueing sppeds (initial cadence/ initial cadence &#x002B;5&#x0025;)</td>
<td valign="top" align="left">Cadence (steps in 30&#x2005;s&#x00D7;2); walking velocity (meters per minute); stride length calculated as (velocity/cadence)&#x2009;&#x00D7;&#x2009;2.</td>
<td valign="top" align="left">KP (a), concurrent, continuous, prescriptive</td>
<td valign="top" align="left">velocity &#x2191;<break/>stride length &#x2191;<break/>cadence &#x2191; (with more sessions)<break/>cadence &#x2191; (with higher GMFCS level)<break/>cadence &#x2191; (with increased cueing speed)<break/>velocity &#x2191; (with higher GMFCS level)<break/>stride length &#x2191; (with higher GMFCS level)</td>
<td valign="top" align="left">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B22">22</xref>)</td>
<td valign="top" align="left">two-group, pre-post interventional design</td>
<td valign="top" align="right">13 (simple:6; complex:7)</td>
<td valign="top" align="right">4:9 (simple 2:4; complex: 2:5)</td>
<td valign="top" align="left">Diplegic CP</td>
<td valign="top" align="left">19.75 (simple: 20.0&#x2009;&#x00B1;&#x2009;2.8 complex: 19.5&#x2009;&#x00B1;&#x2009;5.0)</td>
<td valign="top" align="left">/</td>
<td valign="top" align="left">Using 30-minute sessions, participants walked while receiving rhythmic auditory stimulation with either simple or complex chord progressions played live by a music therapist, with tempo adjustments to optimize gait stability over 4 weeks.</td>
<td valign="top" align="left">Intervention (12 sessions)</td>
<td valign="top" align="left">pre-test and post-test design for both: RAS with simple chords/RAS with complex chords</td>
<td valign="top" align="left">Spatiotemporal parameters (cadence, velocity, step length, step time, step width, single/double support); kinematic parameters (dynamic joint ROM for pelvis, hip, knee, and ankle across multiple planes).</td>
<td valign="top" align="left">KP (a), concurrent, continuous, prescriptive</td>
<td valign="top" align="left">cadence &#x2191;<break/>walking velocity &#x2191;<break/>stride length &#x2191;<break/>hip extension at terminal stance &#x2191;<break/>ankle plantar flexion during preswing &#x2191; (complex RAS &#x003E; simple RAS)<break/>ankle dorsiflexion ROM &#x2191; (complex RAS &#x003E; simple RAS)</td>
<td valign="top" align="left">High</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="s3b"><title>Risk of bias</title>
<p>The results of the risk of bias analysis are presented in <xref ref-type="fig" rid="F2">Figure&#x00A0;2A</xref> for the five RCTs studies and in <xref ref-type="fig" rid="F2">Figure&#x00A0;2B</xref> for the remaining 16 studies. All of the included studies showed at least &#x201C;some concerns&#x201D; in their study designs. The results of the MINORS assessment were as follows:</p>
<fig id="F2" position="float"><label>Figure&#x00A0;2</label>
<caption><p><bold>(A)</bold> quality assessment of randomized studies according to the RoB2 assessment, <bold>(B)</bold> quality assessment of non-randomized studies according to the MINORS assessment with the total value adjusted to percentage on the <italic>x</italic>-axis.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fresc-07-1638091-g002.tif"><alt-text content-type="machine-generated">Panel A displays a table evaluating four studies across six bias domains with symbols indicating risk levels: green plus for low risk, yellow question mark for unclear risk, and red minus for high risk. Panel B shows a bar graph comparing study quality percentages for multiple included studies using the MINORS score, with color-coded bars denoting comparative and non-comparative studies, and dashed lines marking 50 percent and 75 percent quality thresholds.</alt-text>
</graphic>
</fig>
<p>T. Booth et al. (<xref ref-type="bibr" rid="B13">13</xref>) 15/24; A. T. C. Booth et al. (<xref ref-type="bibr" rid="B14">14</xref>) 11/16; Argunsah and Yalcin (<xref ref-type="bibr" rid="B30">30</xref>) 18/24; Baram and Lenger (<xref ref-type="bibr" rid="B26">26</xref>) 10/16; Colborne et al. (<xref ref-type="bibr" rid="B17">17</xref>) 14/24; Conner et al. (<xref ref-type="bibr" rid="B19">19</xref>) 12/16; Conrad and Bleck (<xref ref-type="bibr" rid="B18">18</xref>) 4/16; Fang and Lerner (<xref ref-type="bibr" rid="B20">20</xref>) 9/16; Flux et al. (<xref ref-type="bibr" rid="B36">36</xref>) 15/24; Gagliardi et al. (<xref ref-type="bibr" rid="B39">39</xref>) 12/16; Gerek and Moghadami (<xref ref-type="bibr" rid="B21">21</xref>) 11/16; Guinet et al. (<xref ref-type="bibr" rid="B34">34</xref>) 10/24; Jiang (<xref ref-type="bibr" rid="B38">38</xref>) 8/16; Kim et al. (<xref ref-type="bibr" rid="B27">27</xref>) 19/24; Kim et al. (<xref ref-type="bibr" rid="B28">28</xref>) 18/24; Kim et al. (<xref ref-type="bibr" rid="B22">22</xref>) 18/24; Kwak (<xref ref-type="bibr" rid="B29">29</xref>) 14/24; Lim et al. (<xref ref-type="bibr" rid="B23">23</xref>) 12/16; Pu et al. (<xref ref-type="bibr" rid="B24">24</xref>) 10/16; Spomer et al. (<xref ref-type="bibr" rid="B25">25</xref>) 13/16; van Gelder et al. (<xref ref-type="bibr" rid="B35">35</xref>) 16/24.</p>
</sec>
<sec id="s3c"><title>Characteristics of the included studies</title>
<p>The studies differed in the duration of the intervention with 13 studies were conducted as a single session intervention (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B14">14</xref>, <xref ref-type="bibr" rid="B19">19</xref>&#x2013;<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B23">23</xref>, <xref ref-type="bibr" rid="B24">24</xref>, <xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B27">27</xref>, <xref ref-type="bibr" rid="B30">30</xref>, <xref ref-type="bibr" rid="B34">34</xref>&#x2013;<xref ref-type="bibr" rid="B36">36</xref>), and 12 studies across multiple sessions (<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B18">18</xref>, <xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B29">29</xref>, <xref ref-type="bibr" rid="B31">31</xref>&#x2013;<xref ref-type="bibr" rid="B33">33</xref>, <xref ref-type="bibr" rid="B37">37</xref>&#x2013;<xref ref-type="bibr" rid="B39">39</xref>). The following sections will present and compare these separately. <xref ref-type="table" rid="T1">Table&#x00A0;1</xref> summarize the characteristics of the single-session studies, while <xref ref-type="table" rid="T2">Table&#x00A0;2</xref> and 5 represent the multi-session studies.</p>
<p>Outcome measures were grouped into three categories as shown in <xref ref-type="fig" rid="F3">Figure&#x00A0;3</xref>: performance measures including basic gait parameters, performance production measures covering biomechanical and kinetic measures, and neuromuscular parameters. In the following section, the study results will be presented according to this structure.</p>
<fig id="F3" position="float"><label>Figure&#x00A0;3</label>
<caption><p>Categorization of the outcome parameters.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fresc-07-1638091-g003.tif"><alt-text content-type="machine-generated">Conceptual diagram shows a progression from left to right labeled Performance, Performance Production, and Neuromuscular, with related walking and joint metrics listed under each heading, accompanied by simple illustrations of a walking person, a knee joint, and an EMG waveform.</alt-text>
</graphic>
</fig>
</sec>
<sec id="s3d"><title>Enhanced performance parameters</title>
<p>Step length improvements were reported in three single session studies (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B23">23</xref>, <xref ref-type="bibr" rid="B30">30</xref>), whereas Argunsah and Yalcin (<xref ref-type="bibr" rid="B30">30</xref>) did not report if these were indeed significant One study found a significant decrease for step length for slower rhythms of RAS (rhythmic auditory stimulation) (<xref ref-type="bibr" rid="B21">21</xref>) which may have been induced through reduced visual flow (compared to normal velocity) as found by Lim et al. (<xref ref-type="bibr" rid="B23">23</xref>). RAS may also lead to significantly reduced step length asymmetry for CP patients with slower functional gait (<xref ref-type="bibr" rid="B27">27</xref>). An increased stride length was reported in two studies (<xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B35">35</xref>). Gerek &#x0026; Moughadami (<xref ref-type="bibr" rid="B21">21</xref>) also reported a reduced stride length in the slowest rhythm of the RAS. Two studies additionally quantified compensatory increases in step width with increasing walking speed (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B21">21</xref>). In the multi-session studies significant step length increases were found in four studies (<xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B33">33</xref>, <xref ref-type="bibr" rid="B39">39</xref>). Stride length improved in five studies (<xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B32">32</xref>, <xref ref-type="bibr" rid="B38">38</xref>, <xref ref-type="bibr" rid="B39">39</xref>) while others showed no significant changes in step length (<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B30">30</xref>, <xref ref-type="bibr" rid="B34">34</xref>) or stride length (<xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B31">31</xref>).</p>
<p>Visual, auditory, RAS and tactile feedback improved walking speed after only one intervention session (<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B23">23</xref>, <xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B30">30</xref>, <xref ref-type="bibr" rid="B34">34</xref>). Visual, auditory and RAS also increased walking velocity in studies conducted over multiple sessions (<xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B29">29</xref>, <xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B32">32</xref>, <xref ref-type="bibr" rid="B38">38</xref>, <xref ref-type="bibr" rid="B39">39</xref>). However, in their findings Kwak (<xref ref-type="bibr" rid="B29">29</xref>) report that the walking speed only increased for the group receiving Therapist guided training (compared to Self guided training) and Jiang (<xref ref-type="bibr" rid="B38">38</xref>) found that level of gross motor functioning had a statistically significant main effect on velocity. The findings of changes in step frequencies showed heterogenous results with some studies providing evidence for an increased step frequency for a single session (<xref ref-type="bibr" rid="B23">23</xref>, <xref ref-type="bibr" rid="B30">30</xref>) and for multiple sessions (<xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B37">37</xref>, <xref ref-type="bibr" rid="B38">38</xref>) while others report decreases (<xref ref-type="bibr" rid="B23">23</xref>, <xref ref-type="bibr" rid="B32">32</xref>). This, however, may also be due to the design of the gait task given, since in some studies the goal was to increase walking speed (<xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B30">30</xref>&#x2013;<xref ref-type="bibr" rid="B32">32</xref>, <xref ref-type="bibr" rid="B34">34</xref>, <xref ref-type="bibr" rid="B37">37</xref>, <xref ref-type="bibr" rid="B39">39</xref>), whereas in others the walking speed was set to a fixed pace (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B19">19</xref>&#x2013;<xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B27">27</xref>&#x2013;<xref ref-type="bibr" rid="B29">29</xref>, <xref ref-type="bibr" rid="B35">35</xref>, <xref ref-type="bibr" rid="B36">36</xref>, <xref ref-type="bibr" rid="B38">38</xref>). Lim et al. (<xref ref-type="bibr" rid="B23">23</xref>) demonstrated that altering optic flow (defined as the pattern of visual motion perceived on the retina relative to walking speed) can modulate step frequency, increasing it with faster optic flow and decreasing it with slower optic flow.</p>
<p>Changes in stance and swing time during gait were reported in only a few studies. In the single-session study by van Gelder et al. (<xref ref-type="bibr" rid="B35">35</xref>), an increased swing time on the affected leg was observed, suggesting improved gait symmetry. Similarly, Nagy et al. (<xref ref-type="bibr" rid="B33">33</xref>) found improvements in stance and swing phase symmetry following multiple sessions of auditory feedback intervention. In another single-session study, Argunsah and Yalcin (<xref ref-type="bibr" rid="B30">30</xref>) reported a decrease in pathologically extended stance percentage using tactile biofeedback. Among multi-session studies, Gagliardi et al. (<xref ref-type="bibr" rid="B39">39</xref>) also observed a decrease of stance time, while Kim et al. (<xref ref-type="bibr" rid="B28">28</xref>) noted modest normalization of the stance and swing phases with RAS. Additionally, Kim et al. (<xref ref-type="bibr" rid="B22">22</xref>) reported a significant increase in swing phase duration and a significant reduction in stance time compared to neurodevelopmental training therapy.</p>
</sec>
<sec id="s3e"><label>3.5</label><title>Performance production measures</title>
<p>The majority of the studies focused on improving joint function. Most studies analyzed ankle, knee, and hip joints individually, with kinematic data analyzed more frequently than kinetic data.</p>
</sec>
<sec id="s3f"><title>Ankle kinematics</title>
<p>In single-session studies, positive effects on ankle kinematics were reported, with increased mean and peak ankle power generation during push-off (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B20">20</xref>), and improved ankle momentum during the stance phase (<xref ref-type="bibr" rid="B20">20</xref>). The increase occurred in studies that provided visual feedback. In Fang and Lerner&#x0027;s (<xref ref-type="bibr" rid="B20">20</xref>) feedback protocol, participants were required to walk on an incline. This induced greater ankle power generation and therefore increased dorsiflexion at heel strike. One study noted a significant increase in ankle dorsiflexion during late stance after visual feedback on hip kinematics but not after feedback on knee kinematics (<xref ref-type="bibr" rid="B35">35</xref>). This increase in ankle dorsiflexion during both stance and swing phases as well as a reduction in excessive ankle plantarflexion at initial contact was shown by Argunsah and Yalcin (<xref ref-type="bibr" rid="B30">30</xref>) using tactile feedback, resulting in improved ankle ROM. In contrast two studies using RAS and one utilizing combined auditory and visual feedback did not observe significant differences in ankle kinematics or range of motion (RoM) (<xref ref-type="bibr" rid="B19">19</xref>, <xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B27">27</xref>).</p>
<p>In multi-session studies, improvements in dorsiflexion during initial contact was one reported outcome measure (<xref ref-type="bibr" rid="B18">18</xref>), particularly benefiting patients with equinus gait. Audiovisual feedback on muscle activation enhanced plantarflexion during push-off (<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B25">25</xref>) and the peak-power generation in the ankle (<xref ref-type="bibr" rid="B17">17</xref>). Gagliardi et al. (<xref ref-type="bibr" rid="B39">39</xref>) using visual feedback demonstrated significant improvements in ankle ROM for flexion-extension during both stance and swing phases, along with increased ankle peak power. Kim et al. (<xref ref-type="bibr" rid="B28">28</xref>) found no statistical differences in ankle kinematic parameters with RAS, while Kim et al. (<xref ref-type="bibr" rid="B22">22</xref>) reported significantly greater ankle plantar flexion at push-off and increased dorsiflexion ROM in the complex RAS group compared to the simple RAS group (i.e., either a simple or complex chord progression was played as RAS).</p>
</sec>
<sec id="s3g"><title>Knee kinematics</title>
<p>Knee kinematics were the second most analyzed joint given the gait deviations of flexed knee joint gait and stiffness in CP. Single-session studies reported significant increases in peak knee extension (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B35">35</xref>, <xref ref-type="bibr" rid="B36">36</xref>). Two studies however found no significant changes in the knee joint kinematics (<xref ref-type="bibr" rid="B19">19</xref>, <xref ref-type="bibr" rid="B27">27</xref>). Greater improvements were observed when feedback was provided on joint angles (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B35">35</xref>) compared to feedback focused on muscle activation or plantar pressure (<xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B36">36</xref>). Argunsah and Yalcin (<xref ref-type="bibr" rid="B30">30</xref>) reported lower knee flexion during both &#x201C;with&#x201D; and &#x201C;without&#x201D; tactile feedback conditions, with increased knee ROM.</p>
<p>Multi-session studies also highlighted positive effects, such as increased knee flexion during the swing phase (<xref ref-type="bibr" rid="B25">25</xref>), reduction of excessive knee flexion at initial contact (<xref ref-type="bibr" rid="B39">39</xref>), increases in knee extension during a passive RoM test (<xref ref-type="bibr" rid="B18">18</xref>) and a decrease in knee joint displacement during mid-stance (<xref ref-type="bibr" rid="B31">31</xref>). Three studies, also reported no significant changes in knee kinematics (<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B28">28</xref>), however one of those were comprised of a small sample size (<xref ref-type="bibr" rid="B17">17</xref>). In a two week follow up measurement the knee flexion was still increased (<xref ref-type="bibr" rid="B25">25</xref>) in the AF group.</p>
</sec>
<sec id="s3h"><title>Hip kinematics</title>
<p>As excessive hip flexion during the stance phase is another common feature of CP gait, particularly in the crouch gait, the hip joint was another joint to target for AF interventions. Single-session studies found increased hip RoM (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B27">27</xref>, <xref ref-type="bibr" rid="B35">35</xref>), but also reported some compensatory movements, such as increased hip abduction, during the swing phase (<xref ref-type="bibr" rid="B13">13</xref>). Other studies found no significant changes in hip kinematics (<xref ref-type="bibr" rid="B19">19</xref>, <xref ref-type="bibr" rid="B20">20</xref>). As for the studies quantifying changes across the knee joint, studies with significant changes across the hip joint used feedback on joint kinematics, while those with non-significant results gave feedback with regards to changes in plantar pressure and EMG signals. Kim et al. (<xref ref-type="bibr" rid="B27">27</xref>), using RAS, also found significantly increased external rotation of the hip joint at initial contact which brings the CP patients closer to the external rotation range of the TD control group.</p>
<p>One multi-session study reported increased hip flexion at initial contact (<xref ref-type="bibr" rid="B25">25</xref>). Kim et al. (<xref ref-type="bibr" rid="B22">22</xref>) and Gagliardi et al. (<xref ref-type="bibr" rid="B39">39</xref>) both observed increased hip extension, with Kim et al. (<xref ref-type="bibr" rid="B22">22</xref>) reporting improvements during terminal stance and Gagliardi et al. (<xref ref-type="bibr" rid="B39">39</xref>) noting enhanced range of motion through improved minimum hip flexion. Similarly, Kim et al. (<xref ref-type="bibr" rid="B28">28</xref>) found reduced excessive hip flexion, though they also reported worsening of hip adduction and internal rotation. In addition, Spomer et al. (<xref ref-type="bibr" rid="B25">25</xref>) observed greater hip flexion during early and late swing phases, while another study found no significant changes (<xref ref-type="bibr" rid="B17">17</xref>).</p>
</sec>
<sec id="s3i"><title>Pelvic kinematics</title>
<p>Pelvic kinematics as an important outcome measure in several studies revealed mixed results regarding intervention effectiveness. In single-session studies, Van Gelder et al. (<xref ref-type="bibr" rid="B35">35</xref>) found that feedback on hip angle significantly increased both pelvic tilt ROM and pelvic obliquity ROM, though this came at the cost of increased trunk and pelvis deviations from normal gait patterns. Tactile biofeedback guidance guided pelvic biomechanics towards a healthy gait pattern, though pelvic obliquity of CP participants remained significantly higher compared to the control group (<xref ref-type="bibr" rid="B30">30</xref>). Other single-session studies found no significant effects on pelvic parameters (<xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B36">36</xref>).</p>
<p>Multi-session studies demonstrated more consistent improvements, with Kim et al. (<xref ref-type="bibr" rid="B22">22</xref>) showing significant increase of anterior pelvic tilt at initial contact and throughout the gait cycle after RAS intervention. Gagliardi et al. (<xref ref-type="bibr" rid="B39">39</xref>) using visual feedback measured improvements in both pelvic tilt ROM and pelvic obliquity ROM bilaterally. However, Spomer et al. (<xref ref-type="bibr" rid="B25">25</xref>) found no significant differences in pelvic kinematics, using an audiovisual biofeedback modality.</p>
</sec>
<sec id="s3j"><title>Enhanced neuromuscular parameters</title>
<p>Spasticity and joint stiffness, caused by overactivation of lower limb muscles, are major contributors to gait abnormalities in individuals with cerebral palsy (CP). Therefore, many studies focused on altering muscle activation patterns using augmented feedback (AF) interventions.</p>
</sec>
<sec id="s3k"><title>Lower leg muscles</title>
<p>In the lower leg the soleus and gastrocnemius, play a critical role in plantarflexing the ankle during the push-off phase, which stabilizes the body and propels the center of mass forward. All studies that measured soleus and gastrocnemius muscle activity reported positive effects of feedback interventions. In the single session studies, an increased activation of the plantar flexors and reduced co-activation with the tibialis anterior was found (<xref ref-type="bibr" rid="B19">19</xref>, <xref ref-type="bibr" rid="B20">20</xref>). Fang and Lerner (<xref ref-type="bibr" rid="B20">20</xref>) observed a 9&#x0025; increase in soleus activity and a 22&#x0025; increase in gastrocnemius activity, while Conner et al. (<xref ref-type="bibr" rid="B19">19</xref>) reported 58&#x0025;&#x2013;82&#x0025; increases in these muscles. Flux et al. (<xref ref-type="bibr" rid="B36">36</xref>) compared EMG-based feedback during early stance, push-off, and both time points combined and reported a decrease of 6.8&#x0025; in triceps surae activity during early stance after early stance and combined feedback and increased activity of 8.1&#x0025; during push-off.</p>
<p>In multi-session studies, results showed similar positive effects. Spomer et al. (<xref ref-type="bibr" rid="B25">25</xref>) reported a 28.5&#x0025; increase in soleus activity during late stance when providing audiovisual feedback on soleus activity. These effects however were short-lasting once the feedback was discontinued. Other studies, such as Colborne et al. (<xref ref-type="bibr" rid="B17">17</xref>), reported long-term decreases in excessive triceps surae activity, but did not report information if the results were significant or if they performed a statistical analysis.</p>
</sec>
<sec id="s3l"><title>Upper leg muscles</title>
<p>The vastus lateralis, responsible for knee stabilization and shock absorption during early stance, was the main upper leg muscle studied. In their single-session study Fang and Lerner (<xref ref-type="bibr" rid="B20">20</xref>) reported a 19.6&#x0025; increase in vastus lateralis activity during incline walking. However, in multi-session studies no significant changes in upper leg muscle activation reported (<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B25">25</xref>).</p>
</sec>
<sec id="s3m"><title>Ankle co-contraction index and muscle synergy adaptations</title>
<p>The ankle co-contraction index measures how well the muscles around the ankle work together, indicating coordination and stability. In the single-session study of Conner et al. (<xref ref-type="bibr" rid="B19">19</xref>), a significant 52&#x0025; increase in the ankle co-contraction index was reported when using EMG-based feedback, but not with plantar-pressure-based feedback. Booth et al. (<xref ref-type="bibr" rid="B13">13</xref>) focused on muscle synergy changes. The changes in muscle synergies were limited to only a few significant adaptations, including the number of synergies that are required to explain at least 90&#x0025; of the variance of muscle activation, but there were no significant changes in the complexity of the synergies. In the multi-session studies, Spomer et al. (<xref ref-type="bibr" rid="B25">25</xref>) reported no significant changes in the co-contraction index after audiovisual feedback.</p>
<p>A more distinct overview about the study characteristics is shown in <xref ref-type="fig" rid="F4">Figure&#x00A0;4</xref> for the single-session studies and <xref ref-type="fig" rid="F5">Figure&#x00A0;5</xref> for the multi-session studies.</p>
<fig id="F4" position="float"><label>Figure&#x00A0;4</label>
<caption><p>Feedback characteristics of single-session studies.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fresc-07-1638091-g004.tif"><alt-text content-type="machine-generated">Flowchart displaying parameters of thirteen single-session studies: modality (visual nine, auditory five, tactile one), focus (KP twelve, KR zero), specificity (qualitative seven, quantitative six), timing (concurrent thirteen, terminal zero), frequency (one hundred percent, thirteen), and level of guidance (prescriptive five, descriptive eight). A note states double naming of parameters is possible if used in combination.</alt-text>
</graphic>
</fig>
<fig id="F5" position="float"><label>Figure&#x00A0;5</label>
<caption><p>Feedback characteristics of single-session studies.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fresc-07-1638091-g005.tif"><alt-text content-type="machine-generated">Flowchart illustrating twelve multi-session studies categorized by modality (visual seven, auditory eleven, tactile zero), focus (KP eleven, KR zero, combined one), specificity (qualitative four, quantitative twelve), timing (concurrent eleven, combined one), frequency (one hundred percent in twelve), and level of guidance (prescriptive five, descriptive seven). Footnote indicates double naming of parameters is possible if combined.</alt-text>
</graphic>
</fig>
</sec>
<sec id="s3n"><title>Level of evidence synthesis</title>
<p>Among the spatiotemporal gait parameters, only velocity showed a strong level of evidence for improvement, supported by consistent findings across multiple high-quality studies. Similarly, increases in ankle kinematics demonstrated strong evidence, while gastrocnemius and soleus activation showed moderate evidence of enhancement. In contrast, findings related to step length, stride length, step width, cadence, knee and hip kinematics, pelvis motion, and muscle synergies were inconsistent or conflicting, resulting in inconclusive evidence. Changes in muscle synergy complexity was supported by a single high-quality study (<xref ref-type="bibr" rid="B13">13</xref>), leading to limited evidence. For quadriceps, tibialis anterior, and ankle co-contraction, conflicting or insufficient data also rendered the evidence inconclusive. Overall, while isolated improvements in specific parameters were observed, particularly in velocity and ankle function, the broader evidence base remains mixed, highlighting the need for further high-quality, consistent research. More detailed information can be found in <xref ref-type="table" rid="T2">Table&#x00A0;2</xref>.</p>
</sec>
</sec>
<sec id="s4" sec-type="discussion"><title>Discussion</title>
<sec id="s4a"><title>Key findings</title>
<p>The objective of this systematic review was to evaluate the effects of augmented feedback on gait parameters in individuals with cerebral palsy and to identify optimal feedback parameters for improving rehabilitation outcomes. This review included 25 studies (13 single-session, 12 multi-session) comprising 409 participants, representing a comprehensive analysis of the current evidence base. The studies included in the review showed considerable heterogeneity in terms of study design, gait tasks employed, outcome measures, intervention protocols, and overall study quality. This variability limits the ability to draw clear conclusions regarding the role of AF in gait rehabilitation in CP and did not allow quantitative meta-analysis to be performed due to substantial differences in outcome measurement methods, intervention protocols, feedback modalities, and participant characteristics across studies. The high degree of clinical and methodological heterogeneity, combined with inconsistent reporting of effect sizes and confidence intervals, made statistical pooling inappropriate and potentially misleading. However, the findings indicate that AF can initiate positive effects on gait performance in patients with mild spastic CP, particularly with respect to improvements in ankle joint function. Spatiotemporal parameters emerged as the most frequently assessed outcome measures, with changes in ankle kinematics being the most consistently reported improvement. Based on our level of evidence synthesis, velocity improvements showed strong evidence (consistently supported by high-quality studies), while ankle kinematics demonstrated moderate to strong evidence. However, many other parameters including step length, stride length, and cadence showed inconclusive evidence due to conflicting findings or reliance on lower-quality studies. Visual feedback modalities, particularly using concurrent and continuous knowledge of performance (KP), showed the most consistent positive effects across outcomes, though auditory feedback demonstrated specific benefits for temporal gait parameters<bold>.</bold> Thus the specific parameters upon which feedback was based seemed to not significantly influence the outcomes. Additionally, the duration of feedback sessions and the dosage of interventions varied significantly across studies. Long-term retention of effects appeared promising, but few studies conducted follow-up assessments, and those that did mostly employed short follow-up intervals.</p>
<p>Study quality assessment revealed significant variability, with eight studies rated as high quality, 13 as moderate quality, and four as low quality. This distribution directly influenced the strength of evidence for different outcomes, with higher-quality studies providing more reliable support for ankle kinematics and velocity improvements.</p>
</sec>
<sec id="s4b"><title>Improvements of impaired gait in spastic CP</title>
<p>Significant improvements in gait patterns were found among patients with spastic CP across various outcome measures, indicating that AF may benefit this subgroup. However, caution is necessary when generalizing these findings to other CP types, as different brain regions may require tailored feedback strategies (<xref ref-type="bibr" rid="B1">1</xref>). The majority of included studies (20 out of 25) focused specifically on spastic CP, with most participants classified as GMFCS levels I and II, limiting generalizability to more severely affected individuals. Several studies used typically developing children as control groups, which may introduce bias since these children&#x0027;s gait patterns are already highly optimized (<xref ref-type="bibr" rid="B40">40</xref>). This limits the interpretation of feedback intervention results compared to CP patients. Most participants were classified as GMFCS level II, suggesting that individuals with milder impairments may respond better to AF. This raises questions about who benefits most from this approach and whether it could be counterproductive for some patients. Research shows variability in responses to AF, with some studies indicating that individuals with lower motor abilities benefit more (<xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B36">36</xref>), while others suggest higher abilities correlate with better outcomes (<xref ref-type="bibr" rid="B20">20</xref>). Age also plays a key role when designing interventions, with evidence supporting better responses from younger patients (<xref ref-type="bibr" rid="B26">26</xref>) while others report more significant improvements for older individuals (<xref ref-type="bibr" rid="B13">13</xref>). Tailoring feedback to specific age groups could enhance efficacy (<xref ref-type="bibr" rid="B4">4</xref>). Flodmark (<xref ref-type="bibr" rid="B41">41</xref>) found positive responses in children with spastic hemiplegia and diplegia, but not in those with cognitive impairments, highlighting the need for further exploration of these distinctions (<xref ref-type="bibr" rid="B3">3</xref>).</p>
<p>Assessment of responder characteristics involved analyzing differences in outcome measures post-feedback, with variability likely stemming from the diverse measures used. The comparability of these measures will be addressed in the next section.</p>
</sec>
<sec id="s4c"><title>Standardized quantification of gait parameters</title>
<p>The quantification of gait improvements was complicated by the use of diverse outcome parameters across the included studies, which were often adapted to specific research goals. For a more comprehensive assessment of AF effects, utilizing a standardized reliable clinical gait analysis framework that encompasses spatiotemporal, kinematic, and kinetic parameters is essential (<xref ref-type="bibr" rid="B3">3</xref>). Several of the included parameters measured are clinically relevant, yet the variation in measurements across studies hinders comparison.</p>
<p>The GMFM-88 is a validated tool for evaluating motor function and gait abilities in CP patients (<xref ref-type="bibr" rid="B42">42</xref>, <xref ref-type="bibr" rid="B43">43</xref>) however, only two studies utilized it (<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B39">39</xref>). Future research should adopt standardized clinical assessments to enhance comparability, particularly using the GMFM-88, which includes dimensions D and E that evaluate standing and dynamic movements like jumping and walking (<xref ref-type="bibr" rid="B3">3</xref>). While GMFM-88 does not provide detailed spatiotemporal neuromuscular or kinematic gait parameters, its use reflects an effort toward standardization and comparability across studies. This highlights a broader issue in the field: many studies use diverse assessment tools, making it difficult to compare outcomes. Future research should prioritize the use of validated and standardized gait analysis methods, such as 3D motion capture, EMG analysis, or instrumented gait analysis, to improve cross-study comparability and data synthesis.</p>
<p>Another important aspect concerns whether improvements in gait parameters translate to enhanced quality of life for CP patients. While improved gait is a key aspect of rehabilitation (<xref ref-type="bibr" rid="B70">70</xref>, <xref ref-type="bibr" rid="B71">71</xref>), Kerr et al. (<xref ref-type="bibr" rid="B73">73</xref>) found no correlation between gait energy efficiency and participation restrictions, suggesting that better gait does not necessarily increase participation in everyday life. Future studies could benefit from integrating questionnaires to assess short- and long-term impacts on quality of life.</p>
<p>Despite the variability in gait measures, some consistent positive effects of AF were observed, particularly in ankle kinematics, which will be further explored in the next section.</p>
</sec>
<sec id="s4d"><title>Changes in ankle joint kinematics through augmented feedback</title>
<p>Changes in the ankle joint were the most consistent adaptation across studies and demonstrated one of the strongest level of evidence in our synthesis. As the most distal joint, the ankle is crucial for initiating ground contact in early stance and facilitating push-off in late stance (<xref ref-type="bibr" rid="B9">9</xref>). High-quality studies consistently demonstrated improvements in ankle power generation, range of motion, and plantarflexor muscle activation, particularly when EMG-based visual feedback was employed (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B36">36</xref>).</p>
<p>About half of the studies used treadmill walking, which differs significantly from ground walking. Research shows that children with CP exhibit distinct kinetic outcomes on a treadmill, including shifts from ankle to hip strategies, increased ankle power during early stance, reduced step length, and wider step width (<xref ref-type="bibr" rid="B44">44</xref>, <xref ref-type="bibr" rid="B45">45</xref>). Additionally, joint angles vary, with greater knee flexion observed at initial contact (<xref ref-type="bibr" rid="B44">44</xref>). Thus, findings from treadmill protocols should be interpreted cautiously, as they may not apply directly to overground walking, limiting external validity. No studies have yet examined the transferability of AF intervention effects from treadmill to overground conditions, indicating a gap for future research.</p>
<p>Several studies reported an increased RoM in the ankle and knee joint. This increase may suggest reduced joint stiffness, a major factor in gait abnormalities in spastic CP (<xref ref-type="bibr" rid="B10">10</xref>, <xref ref-type="bibr" rid="B46">46</xref>). Abnormally high stiffness may be attributed to neural factors like spasticity or non-neural factors linked to altered tissue properties (<xref ref-type="bibr" rid="B10">10</xref>). Effective gait rehabilitation must address the underlying causes of stiffness. AF as an intervention focuses on changing muscle activity which may then also affect tissue properties in the long term. Indeed, conditioning of abnormally high reflexes in spastic spinal cord patients has shown a significant potential in reducing spasticity without the need for medications (<xref ref-type="bibr" rid="B47">47</xref>, <xref ref-type="bibr" rid="B48">48</xref>). However, projecting these findings to CP populations requires caution, as the underlying pathophysiology differs significantly from spinal cord injury. While AF may contribute to improved motor control and potentially influence tissue properties over time, claims about reducing surgical interventions in CP remain speculative and require further investigation. Thus, individualized AF designs, based on thorough clinical evaluations, is essential for targeting common gait limitations.</p>
</sec>
<sec id="s4e"><title>The role of feedback modality and the parameter the feedback is based on in improved gait</title>
<p>The studies included in this review utilized a variety of feedback modalities, ranging from visual, auditory, and audiovisual. However, none incorporated tactile feedback, such as vibration or pressure except for one recent study (<xref ref-type="bibr" rid="B30">30</xref>) that demonstrated promising results with tactile vibration feedback for trunk control<bold>.</bold> Based on our evidence synthesis, visual feedback showed the strongest and most consistent effects across multiple gait parameters, particularly when delivered as concurrent, continuous knowledge of performance (KP). Auditory feedback, especially rhythmic auditory stimulation (RAS), demonstrated specific benefits for temporal parameters like cadence and stride timing.</p>
<p>An important distinction between general auditory feedback and rhythmic auditory stimulation (RAS) has to be pointed out. While both fall under the auditory modality, RAS specifically targets temporal gait aspects through rhythmic cueing, whereas general auditory feedback may provide information about various gait and performance parameters without the rhythmic aspect. Studies using RAS consistently showed improvements in temporal parameters, with Kim et al. (<xref ref-type="bibr" rid="B28">28</xref>) suggesting that RAS primarily affects pelvic and hip movement rather than distal movements of the knee, ankle, or foot.</p>
<p>Certain feedback modalities were frequently paired with specific parameters as shown in <xref ref-type="fig" rid="F6">Figure&#x00A0;6</xref>. Auditory feedback was typically used for plantar pressure and spatiotemporal data, while visual and audiovisual feedback were more commonly applied to kinematic and EMG data. This correlation may give the misleading impression that only certain modalities are effective for specific outcomes. However, the modality and measured outcomes were often aligned, as studies providing feedback on kinematic data primarily assessed kinematic outcomes, and similarly for EMG.</p>
<fig id="F6" position="float"><label>Figure&#x00A0;6</label>
<caption><p>Single-session studies (Left) and multi-session studies (Right) in relation to the parameter the feedback was based on (colour of the reference) and the significant outcomes that increased (green), decreased (red), did not show significant effects (grey), and were not measured (white).</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fresc-07-1638091-g006.tif"><alt-text content-type="machine-generated">Side-by-side heatmaps compare outcome parameters from single-session and multi-session studies using colored cells for positive, neutral, negative, or unmeasured effects. Outcomes include gait measures and EMG data, with a legend explaining color codes and categories. Individual study references are listed on the vertical axis, and outcome types on the horizontal axis.</alt-text>
</graphic>
</fig>
<p>Another notable trend was the increased use of visual and audiovisual feedback in more recent studies, likely due to advancements in data visualization technologies (<xref ref-type="bibr" rid="B13">13</xref>). However, approximately 34&#x0025; of individuals with CP, especially younger children, experience cerebral visual impairment, making visual feedback less suitable for some patients (<xref ref-type="bibr" rid="B49">49</xref>). For these individuals, auditory feedback may be more effective. Selecting feedback modalities and parameters should be tailored to the individual&#x0027;s needs, especially considering sensory impairments (<xref ref-type="bibr" rid="B1">1</xref>).</p>
<p>The differential effectiveness of feedback modalities can be attributed to several neurophysiological and practical factors. Visual feedback appears particularly effective for kinematic parameters because it may leverage the brain&#x0027;s robust visual-motor integration pathways, allowing patients to directly observe and correct movement patterns in real-time (<xref ref-type="bibr" rid="B50">50</xref>). This is especially beneficial for individuals with spastic CP who retain intact visual processing, as visual feedback may bypass impaired proprioceptive pathways and provide clear, interpretable movement information (<xref ref-type="bibr" rid="B51">51</xref>). However, the approximately 35&#x0025;&#x2013;85&#x0025; prevalence (<xref ref-type="bibr" rid="B52">52</xref>, <xref ref-type="bibr" rid="B53">53</xref>) of cerebral visual impairment in CP populations limits visual feedback applicability. Particularly in individuals with higher GMFCS levels, where the percentage of visual impairments increases as well (<xref ref-type="bibr" rid="B53">53</xref>).</p>
<p>Auditory feedback, especially RAS, demonstrates superior effectiveness for spatiotemporal parameters due to the strong neural coupling between auditory processing and motor timing networks in the brainstem and cerebellum (<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B28">28</xref>). The rhythmic nature of auditory cues can entrain motor patterns through subcortical pathways that may remain relatively preserved in CP (<xref ref-type="bibr" rid="B29">29</xref>). Additionally, auditory feedback offers advantages in patients with visual impairments and may be less cognitively demanding than complex visual displays. The often lower technological requirements of auditory feedback systems also enhance clinical feasibility compared to sophisticated visual display systems (<xref ref-type="bibr" rid="B8">8</xref>).</p>
</sec>
<sec id="s4f"><title>Implications for feedback scheduling, timing, and long-term effects</title>
<sec id="s4f1"><title>Session duration and frequency</title>
<p>The duration of feedback sessions varied significantly across studies, making it difficult to draw firm conclusions. Nearly half of the studies (13 out of 25) were single-session studies. As shown in several studies with stroke patients, a single session gait training protocol typically results in immediate effects on gait parameters (<xref ref-type="bibr" rid="B54">54</xref>, <xref ref-type="bibr" rid="B55">55</xref>) which may not be sustained in the long term (<xref ref-type="bibr" rid="B55">55</xref>).</p>
<p>In multi-session studies, session length and frequency also varied, a trend seen in other reviews on augmented feedback in CP (<xref ref-type="bibr" rid="B5">5</xref>, <xref ref-type="bibr" rid="B6">6</xref>). State-of-the-art gait rehabilitation methods, like robotic or body weight-assisted training, usually last 30 to 60&#x2005;min, 2&#x2013;5 times per week (<xref ref-type="bibr" rid="B71">71</xref>), but it remains unclear if this also applies to augmented feedback interventions.</p>
<p>The studies included participants from various age groups, with many focusing on children but also representing adults. While developing a near-normal gait pattern early in life is crucial, research shows that gait abilities tend to decline with age in adults with CP (<xref ref-type="bibr" rid="B74">74</xref>), highlighting the need for targeted gait interventions across all ages. Motor learning evolves significantly during childhood (<xref ref-type="bibr" rid="B75">75</xref>), and declines in motor learning capacity have been observed in older adults (<xref ref-type="bibr" rid="B77">77</xref>). Cognitive impairments can further impact motor learning (<xref ref-type="bibr" rid="B76">76</xref>), making it important to tailor the duration and frequency of feedback to suit both age and cognitive abilities (<xref ref-type="bibr" rid="B4">4</xref>).</p>
<p>All studies used continuous feedback, but when considering that constant feedback may lead to cognitive overload and dependency on the feedback system, this may limit the patients&#x0027; use of intrinsic feedback like proprioception (<xref ref-type="bibr" rid="B4">4</xref>, <xref ref-type="bibr" rid="B56">56</xref>). For complex motor tasks such as walking, high feedback availability therefore may help in early learning phases (<xref ref-type="bibr" rid="B57">57</xref>) but a &#x201C;faded&#x201D; feedback approach&#x2014;intense at first, then gradually reduced&#x2014;may be more beneficial to promote long-term skill transfer.</p>
</sec>
<sec id="s4f2"><title>Long-term effects</title>
<p>Evaluating long-term effects is a key challenge in gait rehabilitation to truly improve patient participation in activities of daily living (<xref ref-type="bibr" rid="B58">58</xref>). Only five studies conducted long-term assessments with very small sample sizes, limiting the ability to draw conclusions about the lasting effects of AF. This was also mentioned in other reviews of AF in CP (<xref ref-type="bibr" rid="B5">5</xref>, <xref ref-type="bibr" rid="B6">6</xref>) and is also a major limitation of this review. The limited follow-up data represents a critical gap in the evidence base, as immediate improvements do not necessarily translate to functional improvements in daily activities or long-term motor learning benefits.</p>
</sec>
</sec>
<sec id="s4g"><title>Level of evidence synthesis and study quality implications</title>
<p>Our systematic evidence synthesis revealed variability in the strength of evidence across different gait parameters (<xref ref-type="table" rid="T3">Table 3</xref>). We found that velocity improvements demonstrated the strongest evidence level, being consistently supported by multiple high-quality studies (<xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B39">39</xref>). Ankle kinematics showed moderate to strong evidence, particularly for ankle power generation and range of motion, supported by several high-quality studies employing EMG-based feedback systems.</p>
<table-wrap id="T3" position="float"><label>Table&#x00A0;3</label>
<caption><p>Level of evidence synthesis for individual outcome parameters.</p></caption>
<table>
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="center"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Outcome parameter</th>
<th valign="top" align="center">Effect direction</th>
<th valign="top" align="center">Association (studies)</th>
<th valign="top" align="center">No association/opposite</th>
<th valign="top" align="center">Level of evidence</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Step Length</td>
<td valign="top" align="left">Increase</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B23">23</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B33">33</xref>, <xref ref-type="bibr" rid="B37">37</xref>, <xref ref-type="bibr" rid="B39">39</xref>)</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B27">27</xref>, <xref ref-type="bibr" rid="B30">30</xref>, <xref ref-type="bibr" rid="B34">34</xref>, <xref ref-type="bibr" rid="B35">35</xref>)</td>
<td valign="top" align="center">Inconclusive</td>
</tr>
<tr>
<td valign="top" align="left">Stride Length</td>
<td valign="top" align="left">Increase</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B32">32</xref>, <xref ref-type="bibr" rid="B33">33</xref>, <xref ref-type="bibr" rid="B35">35</xref>, <xref ref-type="bibr" rid="B38">38</xref>, <xref ref-type="bibr" rid="B39">39</xref>)</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B24">24</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B30">30</xref>, <xref ref-type="bibr" rid="B31">31</xref>)</td>
<td valign="top" align="center">Inconclusive</td>
</tr>
<tr>
<td valign="top" align="left">Step Width</td>
<td valign="top" align="left">Decrease</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B37">37</xref>, <xref ref-type="bibr" rid="B39">39</xref>)</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B35">35</xref>)</td>
<td valign="top" align="center">Inconclusive</td>
</tr>
<tr>
<td valign="top" align="left">Cadence</td>
<td valign="top" align="left">Increase</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B23">23</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B37">37</xref>, <xref ref-type="bibr" rid="B38">38</xref>)</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B29">29</xref>, <xref ref-type="bibr" rid="B30">30</xref>, <xref ref-type="bibr" rid="B32">32</xref>)</td>
<td valign="top" align="center">Inconclusive</td>
</tr>
<tr>
<td valign="top" align="left">Velocity</td>
<td valign="top" align="left">Increase</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B21">21</xref>&#x2013;<xref ref-type="bibr" rid="B23">23</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B29">29</xref>, <xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B32">32</xref>, <xref ref-type="bibr" rid="B34">34</xref>, <xref ref-type="bibr" rid="B37">37</xref>&#x2013;<xref ref-type="bibr" rid="B39">39</xref>)</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B30">30</xref>)</td>
<td valign="top" align="center">Strong</td>
</tr>
<tr>
<td valign="top" align="left">Ankle</td>
<td valign="top" align="left">Increase</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B18">18</xref>, <xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B30">30</xref>, <xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B35">35</xref>, <xref ref-type="bibr" rid="B36">36</xref>, <xref ref-type="bibr" rid="B39">39</xref>)</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B19">19</xref>, <xref ref-type="bibr" rid="B27">27</xref>, <xref ref-type="bibr" rid="B28">28</xref>)</td>
<td valign="top" align="center">Strong</td>
</tr>
<tr>
<td valign="top" align="left">Knee</td>
<td valign="top" align="left">Increase</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B18">18</xref>, <xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B35">35</xref>, <xref ref-type="bibr" rid="B36">36</xref>, <xref ref-type="bibr" rid="B39">39</xref>)</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B19">19</xref>, <xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B27">27</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B30">30</xref>)</td>
<td valign="top" align="center">Inconclusive</td>
</tr>
<tr>
<td valign="top" align="left">Hip</td>
<td valign="top" align="left">Increase</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B14">14</xref>, <xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B27">27</xref>, <xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B35">35</xref>, <xref ref-type="bibr" rid="B39">39</xref>)</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B19">19</xref>, <xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B30">30</xref>)</td>
<td valign="top" align="center">Inconclusive</td>
</tr>
<tr>
<td valign="top" align="left">Pelvis</td>
<td valign="top" align="left">Decrease</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B30">30</xref>, <xref ref-type="bibr" rid="B39">39</xref>)</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B35">35</xref>, <xref ref-type="bibr" rid="B36">36</xref>)</td>
<td valign="top" align="center">Inconclusive</td>
</tr>
<tr>
<td valign="top" align="left">Muscle Synergies</td>
<td valign="top" align="left">Increase</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B14">14</xref>)</td>
<td valign="top" align="left">&#x2013;</td>
<td valign="top" align="center">Limited</td>
</tr>
<tr>
<td valign="top" align="left">Soleus (SOL) Activation</td>
<td valign="top" align="left">Increase</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B19">19</xref>, <xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B36">36</xref>)</td>
<td valign="top" align="left">&#x2013;</td>
<td valign="top" align="center">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">Gastrocnemius (GASTRO) Activation</td>
<td valign="top" align="left">Increase</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B19">19</xref>, <xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B36">36</xref>)</td>
<td valign="top" align="left">&#x2013;</td>
<td valign="top" align="center">Moderate</td>
</tr>
<tr>
<td valign="top" align="left">Quadriceps (VL/Quad)</td>
<td valign="top" align="left">Increase</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B20">20</xref>)</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B17">17</xref>)</td>
<td valign="top" align="center">Inconclusive</td>
</tr>
<tr>
<td valign="top" align="left">Tibialis Anterior (TA)</td>
<td valign="top" align="left">Increase</td>
<td valign="top" align="left">&#x2013;</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B17">17</xref>)</td>
<td valign="top" align="center">Inconclusive</td>
</tr>
<tr>
<td valign="top" align="left">Ankle Co-Contraction</td>
<td valign="top" align="left">Decrease</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B19">19</xref>)</td>
<td valign="top" align="left">(<xref ref-type="bibr" rid="B25">25</xref>)</td>
<td valign="top" align="center">Inconclusive</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>In contrast, many spatiotemporal parameters including step length, stride length, and cadence showed inconclusive evidence due to conflicting findings across studies of varying quality. The heterogeneity in study quality significantly influenced these results, with lower-quality studies often reporting inconsistent or contradictory findings. This pattern underscores the importance of rigorous study design and standardized outcome measures in AF research.</p>
<p>The distribution of study quality (32&#x0025; high, 52&#x0025; moderate, 16&#x0025; low) highlights the need for more high-quality research to strengthen the evidence base. Studies rated as low quality were primarily limited by small sample sizes, lack of control groups or insufficient reporting of significant results, factors that directly impact the reliability of their findings.</p>
</sec>
<sec id="s4h"><title>Impact of study biases on conclusions</title>
<p>The identified biases in included studies significantly influence the interpretation of our findings and limit the generalizability of conclusions. The predominant use of typically developing children as control groups (seen in 40&#x0025; of studies) introduces a fundamental bias, as these children possess optimized gait patterns that may not reflect realistic improvement targets for CP patients. This bias may amplify effect sizes and creates unrealistic expectations for therapeutic outcomes, as the comparison represents an idealized rather than clinically relevant benchmark.</p>
<p>Sample size limitations affected 60&#x0025; of studies, with many reporting fewer than 15 participants per group. This underpowering substantially increases the risk of both Type I and Type II errors, potentially leading to false-positive findings for some parameters while missing genuine but smaller effects for others. The predominant focus on GMFCS levels I and II (representing 85&#x0025; of all participants) creates a selection bias that limits applicability to more severely affected individuals, who may actually benefit most from augmented feedback interventions but require different implementation strategies.</p>
<p>The heterogeneity in outcome measures further adds to these biases, as studies may inadvertently select measures that favor their specific intervention approach, creating an appearance of effectiveness that may not translate to standardized clinical assessments.</p>
</sec>
<sec id="s4i"><title>Limitations</title>
<p>This systematic review has several limitations that need to be addressed. First, the decision to include various study designs (RCTs, crossover studies, single-group pre-post designs) was made to capture the full scope of available evidence in this emerging field, recognizing that while RCTs provide the strongest evidence, the limited number of high-quality RCTs would have significantly restricted our ability to comprehensively evaluate AF effects. This inclusive approach, while potentially limiting the strength of conclusions, provides a more complete picture of the current evidence landscape and identifies areas where higher-quality research is urgently needed. To overcome this limitation to some degree, we performed a level of evidence assessement. Additionally, it was not possible to compare AF directly to state-of-the-art gait rehabilitation approaches such as robotic-assisted training or functional electrical stimulation, as included studies primarily used traditional gait training or no-feedback controls.</p>
<p>Second, interventions involving robotic or exoskeleton-based feedback were excluded because these systems provide externally-generated tactile and mechanical feedback rather than self-produced feedback. This distinction was important to maintain focus on interventions that enhance the patient&#x0027;s own sensory feedback systems rather than replacing them with external mechanical assistance. However, this exclusion may have limited our understanding of the broader landscape of feedback-enhanced gait rehabilitation.</p>
<p>The main limitation was the lack of statistical comparison between the outcomes of the studies, which is essential to quantify the significance of findings. This was mainly due to the heterogeneity of outcome measures, as most studies used different methods, evaluation tests or gait parameters. Therefore, this systematic review summarizes the main findings in a descriptive manner, albeit providing a level of evidence synthesis and discusses the implications of AF for gait rehabilitation in CP. This descriptive approach, while necessary given the heterogeneity, limits our ability to provide definitive clinical recommendations and effect size estimates. Importantly this highlights the urgent need for more stringent RCT study designs which are both complex and costly.</p>
</sec>
</sec>
<sec id="s5" sec-type="conclusions"><title>Conclusion and outlook for future research</title>
<p>This review aimed to evaluate the effects of AF in gait rehabilitation for CP. Overall, AF showed promising results in improving gait parameters, particularly in spastic CP. However, the evidence remains limited, and it is difficult to make definitive conclusions for all CP subtypes. The studies reviewed demonstrated that AF has a greater impact on gait function than traditional therapy alone, benefiting both kinematic and neuromuscular aspects. Despite these positive trends, the heterogeneity of the studies made it challenging to draw comprehensive conclusions.</p>
<p>Our level of evidence synthesis revealed that while some parameters like velocity and ankle kinematics show strong to moderate evidence for improvement, many other gait parameters remain inconclusive due to study quality limitations and conflicting findings (<xref ref-type="table" rid="T3">Table 3</xref>). Importantly, the methodological quality of the included studies varied considerably, which affects the overall confidence in the reported effects. While some parameters such as velocity and ankle kinematics were supported by consistent findings from high-quality studies (indicating strong evidence), many other outcomes showed inconclusive or limited evidence due to inconsistent findings or reliance on lower-quality data. Therefore, the interpretation of the benefits of AF should be made with caution, especially in areas where study quality was low or results were conflicting.</p>
<p>Key areas for future research include assessing the long-term effects and transferability of AF, establishing guidelines for its duration and dosage, and determining the most effective feedback designs for specific gait abnormalities. Future studies should prioritize randomized controlled trial designs with adequate sample sizes, standardized outcome measures, and longer follow-up periods to address the current evidence gaps. Developing easy-to-use devices for home-based AF practice and investigating potential long-term effects, such as feedback dependency, are also important. Additionally, protocols from single-session studies should be tested in multi-session interventions to evaluate long-term outcomes.</p>
<p>In summary, AF appears to be a promising tool for gait rehabilitation in children with CP, particularly for improving velocity and ankle kinematics. However, current findings are constrained by methodological limitations, such as small sample sizes, inconsistent outcome measures, and participant selection biases. These factors limit the strength and generalizability of the conclusions. While early results are encouraging, especially in spastic CP, the evidence remains insufficient to support widespread clinical adoption. Well-designed, large-scale studies are essential to validate the effectiveness of AF, explore its long-term impact, and inform evidence-based guidelines for clinical implementation.</p>
</sec>
</body>
<back>
<sec id="s6" sec-type="author-contributions"><title>Author contributions</title>
<p>LH: Methodology, Writing &#x2013; original draft, Visualization, Conceptualization, Data curation, Formal analysis. NM-K: Writing &#x2013; original draft, Formal analysis, Methodology, Conceptualization.</p>
</sec>
<sec id="s8" sec-type="COI-statement"><title>Conflict of interest</title>
<p>The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
<p>The author NM-K declared that they were an editorial board member of Frontiers at the time of submission. This had no impact on the peer review process and the final decision.</p>
</sec>
<sec id="s9" sec-type="ai-statement"><title>Generative AI statement</title>
<p>The author(s) declared that generative AI was not used in the creation of this manuscript.</p>
<p>Any alternative text (alt text) provided alongside figures in this article has been generated by Frontiers with the support of artificial intelligence and reasonable efforts have been made to ensure accuracy, including review by the authors wherever possible. If you identify any issues, please contact us.</p>
</sec>
<sec id="s11" sec-type="disclaimer"><title>Publisher&#x0027;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec id="s10" sec-type="supplementary-material"><title>Supplementary material</title>
<p>The Supplementary Material for this article can be found online at: <ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/fresc.2026.1638091/full#supplementary-material">https://www.frontiersin.org/articles/10.3389/fresc.2026.1638091/full&#x0023;supplementary-material</ext-link></p>
<supplementary-material xlink:href="Datasheet1.pdf" id="SM1" mimetype="application/pdf"/>
</sec>
<ref-list><title>References</title>
<ref id="B1"><label>1.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Zhou</surname> <given-names>J</given-names></name> <name><surname>Butler</surname> <given-names>EE</given-names></name> <name><surname>Rose</surname> <given-names>J</given-names></name></person-group>. <article-title>Neurologic correlates of gait abnormalities in cerebral palsy: implications for treatment</article-title>. <source>Front Hum Neurosci</source>. (<year>2017</year>) <volume>11</volume>:<fpage>228551</fpage>. <pub-id pub-id-type="doi">10.3389/fnhum.2017.00103</pub-id></mixed-citation></ref>
<ref id="B2"><label>2.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sheu</surname> <given-names>J</given-names></name> <name><surname>Cohen</surname> <given-names>D</given-names></name> <name><surname>Sousa</surname> <given-names>T</given-names></name> <name><surname>Pham</surname> <given-names>KLD</given-names></name></person-group>. <article-title>Cerebral palsy: current concepts and practices in musculoskeletal care</article-title>. <source>Pediatr Rev</source>. (<year>2022</year>) <volume>43</volume>(<issue>10</issue>):<fpage>572</fpage>&#x2013;<lpage>81</lpage>. <pub-id pub-id-type="doi">10.1542/PIR.2022-005657</pub-id><pub-id pub-id-type="pmid">36180545</pub-id></mixed-citation></ref>
<ref id="B3"><label>3.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Armand</surname> <given-names>S</given-names></name> <name><surname>Decoulon</surname> <given-names>G</given-names></name> <name><surname>Bonnefoy-Mazure</surname> <given-names>A</given-names></name></person-group>. <article-title>Gait analysis in children with cerebral palsy</article-title>. <source>EFORT Open Rev</source>. (<year>2016</year>) <volume>1</volume>(<issue>12</issue>):<fpage>448</fpage>. <pub-id pub-id-type="doi">10.1302/2058-5241.1.000052</pub-id><pub-id pub-id-type="pmid">28698802</pub-id></mixed-citation></ref>
<ref id="B4"><label>4.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sigrist</surname> <given-names>R</given-names></name> <name><surname>Rauter</surname> <given-names>G</given-names></name> <name><surname>Riener</surname> <given-names>R</given-names></name> <name><surname>Wolf</surname> <given-names>P</given-names></name></person-group>. <article-title>Augmented visual, auditory, haptic, and multimodal feedback in motor learning: a review</article-title>. <source>Psychon Bull Rev</source>. (<year>2012</year>) <volume>20</volume>(<issue>1</issue>):<fpage>21</fpage>&#x2013;<lpage>53</lpage>. <pub-id pub-id-type="doi">10.3758/S13423-012-0333-8</pub-id></mixed-citation></ref>
<ref id="B5"><label>5.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Robert</surname> <given-names>MT</given-names></name> <name><surname>Sambasivan</surname> <given-names>K</given-names></name> <name><surname>Levin</surname> <given-names>MF</given-names></name></person-group>. <article-title>Extrinsic feedback and upper limb motor skill learning in typically-developing children and children with cerebral palsy: review</article-title>. <source>Restor Neurol Neurosci</source>. (<year>2017</year>) <volume>35</volume>(<issue>2</issue>):<fpage>171</fpage>&#x2013;<lpage>84</lpage>. <pub-id pub-id-type="doi">10.3233/RNN-160688</pub-id><pub-id pub-id-type="pmid">28282845</pub-id></mixed-citation></ref>
<ref id="B6"><label>6.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>MacIntosh</surname> <given-names>A</given-names></name> <name><surname>Lam</surname> <given-names>E</given-names></name> <name><surname>Vigneron</surname> <given-names>V</given-names></name> <name><surname>Vignais</surname> <given-names>N</given-names></name> <name><surname>Biddiss</surname> <given-names>E</given-names></name></person-group>. <article-title>Biofeedback interventions for individuals with cerebral palsy: a systematic review</article-title>. <source>Disabil Rehabil</source>. (<year>2019</year>) <volume>41</volume>(<issue>20</issue>):<fpage>2369</fpage>&#x2013;<lpage>91</lpage>. <pub-id pub-id-type="doi">10.1080/09638288.2018.1468933</pub-id><pub-id pub-id-type="pmid">29756481</pub-id></mixed-citation></ref>
<ref id="B7"><label>7.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Chamorro-Moriana</surname> <given-names>G</given-names></name> <name><surname>Moreno</surname> <given-names>AJ</given-names></name> <name><surname>Sevillano</surname> <given-names>JL</given-names></name></person-group>. <article-title>Technology-Based feedback and its efficacy in improving gait parameters in patients with abnormal gait: a systematic review</article-title>. <source>Sensors</source>. (<year>2018</year>) <volume>18</volume>(<issue>1</issue>):<fpage>1</fpage>. <pub-id pub-id-type="doi">10.3390/s18010142</pub-id></mixed-citation></ref>
<ref id="B8"><label>8.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ghai</surname> <given-names>S</given-names></name> <name><surname>Hitzig</surname> <given-names>SL</given-names></name> <name><surname>Eberlin</surname> <given-names>L</given-names></name> <name><surname>Melo</surname> <given-names>J</given-names></name> <name><surname>Mayo</surname> <given-names>AL</given-names></name> <name><surname>Blanchette</surname> <given-names>V</given-names></name><etal/></person-group> <article-title>Reporting of rehabilitation outcomes in the traumatic lower limb amputation literature: a systematic review</article-title>. <source>Arch Phys Med Rehabil</source>. (<year>2024</year>) <volume>105</volume>(<issue>6</issue>):<fpage>1158</fpage>&#x2013;<lpage>70</lpage>. <pub-id pub-id-type="doi">10.1016/j.apmr.2023.08.028</pub-id><pub-id pub-id-type="pmid">37708929</pub-id></mixed-citation></ref>
<ref id="B9"><label>9.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>G&#x00F6;tz-Neumann</surname> <given-names>K</given-names></name></person-group>. <comment>&#x2018;Gehen verstehen&#x2019;: So geht&#x2019;s! &#x2013; Physiologie des menschlichen Gangbildes; 2.5 Kinematik und Kinetik der Gangphasen &#x2013; Schl&#x00FC;sselkonzept. In Gehen verstehen: Ganganalyse in der Physiotherapie (4 ed., pp. 58&#x2013;63). <italic>Georg Thieme Verlag KG</italic>. (2016)</comment>.</mixed-citation></ref>
<ref id="B10"><label>10.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>De Gooijer-Van De Groep</surname> <given-names>KL</given-names></name> <name><surname>De Vlugt</surname> <given-names>E</given-names></name> <name><surname>De Groot</surname> <given-names>JH</given-names></name> <name><surname>Van Der Heijden-Maessen</surname> <given-names>HC</given-names></name> <name><surname>Wielheesen</surname> <given-names>DH</given-names></name> <name><surname>Van Wijlen-Hempel</surname> <given-names>RS</given-names></name><etal/></person-group> <article-title>Differentiation between non-neural and neural contributors to ankle joint stiffness in cerebral palsy</article-title>. <source>J Neuroeng Rehabil</source>. (<year>2013</year>) <volume>10</volume>(<issue>1</issue>):<fpage>81</fpage>. <pub-id pub-id-type="doi">10.1186/1743-0003-10-81</pub-id><pub-id pub-id-type="pmid">23880287</pub-id></mixed-citation></ref>
<ref id="B11"><label>11.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Page</surname> <given-names>MJ</given-names></name> <name><surname>McKenzie</surname> <given-names>JE</given-names></name> <name><surname>Bossuyt</surname> <given-names>PM</given-names></name> <name><surname>Boutron</surname> <given-names>I</given-names></name> <name><surname>Hoffmann</surname> <given-names>TC</given-names></name> <name><surname>Mulrow</surname> <given-names>CD</given-names></name><etal/></person-group> <article-title>The PRISMA 2020 statement: an updated guideline for reporting systematic reviews</article-title>. <source>Br Med J</source>. (<year>2021</year>) <volume>372</volume>:<fpage>n71</fpage>. <pub-id pub-id-type="doi">10.1136/BMJ.N71</pub-id></mixed-citation></ref>
<ref id="B12"><label>12.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>van de Schoot</surname> <given-names>R</given-names></name> <name><surname>de Bruin</surname> <given-names>J</given-names></name> <name><surname>Schram</surname> <given-names>R</given-names></name> <name><surname>Zahedi</surname> <given-names>P</given-names></name> <name><surname>de Boer</surname> <given-names>J</given-names></name> <name><surname>Weijdema</surname> <given-names>F</given-names></name><etal/></person-group> <article-title>An open source machine learning framework for efficient and transparent systematic reviews</article-title>. <source>Nature Machine Intelligence</source>. (<year>2021</year>) <volume>3</volume>(<issue>2</issue>):<fpage>125</fpage>&#x2013;<lpage>33</lpage>. <pub-id pub-id-type="doi">10.1038/s42256-020-00287-7</pub-id></mixed-citation></ref>
<ref id="B13"><label>13.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Booth</surname> <given-names>AT</given-names></name> <name><surname>Buizer</surname> <given-names>AI</given-names></name> <name><surname>Harlaar</surname> <given-names>J</given-names></name> <name><surname>Steenbrink</surname> <given-names>F</given-names></name> <name><surname>van der Krogt</surname> <given-names>MM</given-names></name></person-group>. <article-title>Immediate effects of immersive biofeedback on gait in children with cerebral palsy</article-title>. <source>Arch Phys Med Rehabil</source>. (<year>2019</year>) <volume>100</volume>(<issue>4</issue>):<fpage>598</fpage>&#x2013;<lpage>605</lpage>. <pub-id pub-id-type="doi">10.1016/J.APMR.2018.10.013</pub-id><pub-id pub-id-type="pmid">30447196</pub-id></mixed-citation></ref>
<ref id="B14"><label>14.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Booth</surname> <given-names>ATC</given-names></name> <name><surname>van der Krogt</surname> <given-names>MM</given-names></name> <name><surname>Harlaar</surname> <given-names>J</given-names></name> <name><surname>Dominici</surname> <given-names>N</given-names></name> <name><surname>Buizer</surname> <given-names>AI</given-names></name></person-group>. <article-title>Muscle synergies in response to biofeedback-driven gait adaptations in children with cerebral palsy</article-title>. <source>Front Physiol</source>. (<year>2019</year>) <volume>10</volume>:<fpage>1208</fpage>. <pub-id pub-id-type="doi">10.3389/FPHYS.2019.01208</pub-id><pub-id pub-id-type="pmid">31611807</pub-id></mixed-citation></ref>
<ref id="B15"><label>15.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Slim</surname> <given-names>K</given-names></name> <name><surname>Nini</surname> <given-names>E</given-names></name> <name><surname>Forestier</surname> <given-names>D</given-names></name> <name><surname>Kwiatkowski</surname> <given-names>F</given-names></name> <name><surname>Panis</surname> <given-names>Y</given-names></name> <name><surname>Chipponi</surname> <given-names>J</given-names></name></person-group>. <article-title>Methodological index for non-randomized studies (minors): development and validation of a new instrument</article-title>. <source>ANZ J Surg</source>. (<year>2003</year>) <volume>73</volume>(<issue>9</issue>):<fpage>712</fpage>&#x2013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1046/J.1445-2197.2003.02748.X</pub-id><pub-id pub-id-type="pmid">12956787</pub-id></mixed-citation></ref>
<ref id="B16"><label>16.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sterne</surname> <given-names>JAC</given-names></name> <name><surname>Savovi&#x0107;</surname> <given-names>J</given-names></name> <name><surname>Page</surname> <given-names>MJ</given-names></name> <name><surname>Elbers</surname> <given-names>RG</given-names></name> <name><surname>Blencowe</surname> <given-names>NS</given-names></name> <name><surname>Boutron</surname> <given-names>I</given-names></name><etal/></person-group> <article-title>Rob 2: a revised tool for assessing risk of bias in randomised trials</article-title>. <source>BMJ (Clinical Research Ed.)</source>. (<year>2019</year>) <volume>366</volume>:<fpage>l4898</fpage>. <pub-id pub-id-type="doi">10.1136/BMJ.L4898</pub-id><pub-id pub-id-type="pmid">31462531</pub-id></mixed-citation></ref>
<ref id="B17"><label>17.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Colborne</surname> <given-names>GR</given-names></name> <name><surname>Wright</surname> <given-names>FV</given-names></name> <name><surname>Naumann</surname> <given-names>S</given-names></name></person-group>. <article-title>Feedback of triceps surae EMG in gait of children with cerebral palsy: a controlled study</article-title>. <source>Arch Phys Med Rehabil</source>. (<year>1994</year>) <volume>75</volume>(<issue>1</issue>):<fpage>40</fpage>&#x2013;<lpage>5</lpage>. <pub-id pub-id-type="doi">10.1016/0003-9993(94)90335-2</pub-id><pub-id pub-id-type="pmid">8291961</pub-id></mixed-citation></ref>
<ref id="B18"><label>18.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Conrad</surname> <given-names>L</given-names></name> <name><surname>Bleck</surname> <given-names>EE</given-names></name></person-group>. <article-title>Augmented auditory feedback in the treatment of Equinus gait in children</article-title>. <source>Dev Med Child Neurol</source>. (<year>1980</year>) <volume>22</volume>(<issue>6</issue>):<fpage>713</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1111/j.1469-8749.1980.tb03737.x</pub-id><pub-id pub-id-type="pmid">7450297</pub-id></mixed-citation></ref>
<ref id="B19"><label>19.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Conner</surname> <given-names>BC</given-names></name> <name><surname>Fang</surname> <given-names>Y</given-names></name> <name><surname>Lerner</surname> <given-names>ZF</given-names></name></person-group>. <article-title>Under pressure: design and validation of a pressure-sensitive insole for ankle plantar flexion biofeedback during neuromuscular gait training</article-title>. <source>J Neuroeng Rehabil</source>. (<year>2022</year>) <volume>19</volume>(<issue>1</issue>):<fpage>135</fpage>. <pub-id pub-id-type="doi">10.1186/S12984-022-01119-Y</pub-id><pub-id pub-id-type="pmid">36482447</pub-id></mixed-citation></ref>
<ref id="B20"><label>20.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Fang</surname> <given-names>Y</given-names></name> <name><surname>Lerner</surname> <given-names>ZF</given-names></name></person-group>. <article-title>Effects of ankle exoskeleton assistance and plantar pressure biofeedback on incline walking mechanics and muscle activity in cerebral palsy</article-title>. <source>J Biomech</source>. (<year>2024</year>) <volume>163</volume>:<fpage>111944</fpage>. <pub-id pub-id-type="doi">10.1016/J.JBIOMECH.2024.111944</pub-id><pub-id pub-id-type="pmid">38219555</pub-id></mixed-citation></ref>
<ref id="B21"><label>21.</label><mixed-citation publication-type="other"><person-group person-group-type="author"><name><surname>Gerek</surname> <given-names>Z</given-names></name> <name><surname>Moughadami</surname> <given-names>AM</given-names></name></person-group>. <article-title>(PDF) Biomechanical Investigation of The Effect of Rhythmic Auditory Stimulation on Walking Skills in Children with Cerebral Palsy</article-title>. <comment>ResearchGate. (2021). Available online at:</comment> <ext-link ext-link-type="uri" xlink:href="https://www.researchgate.net/publication/351371294_Biomechanical_Investigation_of_The_Effect_of_Rhythmic_Auditory_Stimulation_on_Walking_Skills_in_Children_with_Cerebral_Palsy">https://www.researchgate.net/publication/351371294_Biomechanical_Investigation_of_The_Effect_of_Rhythmic_Auditory_Stimulation_on_Walking_Skills_in_Children_with_Cerebral_Palsy</ext-link> <comment>(Accessed June 20, 2024)</comment>.</mixed-citation></ref>
<ref id="B22"><label>22.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kim</surname> <given-names>SJ</given-names></name> <name><surname>Yoo</surname> <given-names>GE</given-names></name> <name><surname>Shin</surname> <given-names>Y-K</given-names></name> <name><surname>Cho</surname> <given-names>S-R</given-names></name></person-group>. <article-title>Gait training for adults with cerebral palsy following harmonic modification in rhythmic auditory stimulation</article-title>. <source>Ann N Y Acad Sci</source>. (<year>2020</year>) <volume>1473</volume>(<issue>1</issue>):<fpage>11</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1111/nyas.14306</pub-id><pub-id pub-id-type="pmid">32356332</pub-id></mixed-citation></ref>
<ref id="B23"><label>23.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lim</surname> <given-names>H</given-names></name></person-group>. <article-title>Effect of the modulation of optic flow speed on gait parameters in children with hemiplegic cerebral palsy</article-title>. <source>J Phys Ther Sci</source>. (<year>2014</year>) <volume>26</volume>(<issue>1</issue>):<fpage>145</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1589/jpts.26.145</pub-id><pub-id pub-id-type="pmid">24567695</pub-id></mixed-citation></ref>
<ref id="B24"><label>24.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Pu</surname> <given-names>F</given-names></name> <name><surname>Ren</surname> <given-names>W</given-names></name> <name><surname>Fan</surname> <given-names>X</given-names></name> <name><surname>Chen</surname> <given-names>W</given-names></name> <name><surname>Li</surname> <given-names>S</given-names></name> <name><surname>Li</surname> <given-names>D</given-names></name><etal/></person-group> <article-title>Real-time feedback of dynamic foot pressure index for gait training of toe-walking children with spastic diplegia</article-title>. <source>Disabil Rehabil</source>. (<year>2017</year>) <volume>39</volume>(<issue>19</issue>):<fpage>1921</fpage>&#x2013;<lpage>5</lpage>. <pub-id pub-id-type="doi">10.1080/09638288.2016.1212114</pub-id><pub-id pub-id-type="pmid">27558231</pub-id></mixed-citation></ref>
<ref id="B25"><label>25.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Spomer</surname> <given-names>AM</given-names></name> <name><surname>Conner</surname> <given-names>BC</given-names></name> <name><surname>Schwartz</surname> <given-names>MH</given-names></name> <name><surname>Lerner</surname> <given-names>ZF</given-names></name> <name><surname>Steele</surname> <given-names>KM</given-names></name></person-group>. <article-title>Audiovisual biofeedback amplifies plantarflexor adaptation during walking among children with cerebral palsy</article-title>. <source>J Neuroeng Rehabil</source>. (<year>2023</year>) <volume>20</volume>(<issue>1</issue>). <pub-id pub-id-type="doi">10.1186/S12984-023-01279-5</pub-id><pub-id pub-id-type="pmid">38062454</pub-id></mixed-citation></ref>
<ref id="B26"><label>26.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Baram</surname> <given-names>Y</given-names></name> <name><surname>Lenger</surname> <given-names>R</given-names></name></person-group>. <article-title>Gait improvement in patients with cerebral palsy by visual and auditory feedback</article-title>. <source>Neuromodulation</source>. (<year>2012</year>) <volume>15</volume>(<issue>1</issue>):<fpage>48</fpage>&#x2013;<lpage>52</lpage>. <comment>discussion 52</comment>. <pub-id pub-id-type="doi">10.1111/j.1525-1403.2011.00412.x</pub-id><pub-id pub-id-type="pmid">22151772</pub-id></mixed-citation></ref>
<ref id="B27"><label>27.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kim</surname> <given-names>SJ</given-names></name> <name><surname>Kwak</surname> <given-names>EE</given-names></name> <name><surname>Park</surname> <given-names>ES</given-names></name> <name><surname>Lee</surname> <given-names>DS</given-names></name> <name><surname>Kim</surname> <given-names>KJ</given-names></name> <name><surname>Song</surname> <given-names>JE</given-names></name><etal/></person-group> <article-title>Changes in gait patterns with rhythmic auditory stimulation in adults with cerebral palsy</article-title>. <source>NeuroRehabilitation</source>. (<year>2011</year>) <volume>29</volume>(<issue>3</issue>):<fpage>233</fpage>&#x2013;<lpage>41</lpage>. <pub-id pub-id-type="doi">10.3233/NRE-2011-0698</pub-id><pub-id pub-id-type="pmid">22142756</pub-id></mixed-citation></ref>
<ref id="B28"><label>28.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kim</surname> <given-names>SJ</given-names></name> <name><surname>Kwak</surname> <given-names>EE</given-names></name> <name><surname>Park</surname> <given-names>ES</given-names></name> <name><surname>Cho</surname> <given-names>S-R</given-names></name></person-group>. <article-title>Differential effects of rhythmic auditory stimulation and neurodevelopmental treatment/bobath on gait patterns in adults with cerebral palsy: a randomized controlled trial</article-title>. <source>Clin Rehabil</source>. (<year>2012</year>) <volume>26</volume>(<issue>10</issue>):<fpage>904</fpage>&#x2013;<lpage>14</lpage>. <pub-id pub-id-type="doi">10.1177/0269215511434648</pub-id><pub-id pub-id-type="pmid">22308559</pub-id></mixed-citation></ref>
<ref id="B29"><label>29.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kwak</surname> <given-names>EE</given-names></name></person-group>. <article-title>Effect of rhythmic auditory stimulation on gait performance in children with spastic cerebral palsy</article-title>. <source>J Music Ther</source>. (<year>2007</year>) <volume>44</volume>(<issue>3</issue>):<fpage>198</fpage>&#x2013;<lpage>216</lpage>. <pub-id pub-id-type="doi">10.1093/jmt/44.3.198</pub-id><pub-id pub-id-type="pmid">17645385</pub-id></mixed-citation></ref>
<ref id="B30"><label>30.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Argunsah</surname> <given-names>H</given-names></name> <name><surname>Yalcin</surname> <given-names>B</given-names></name></person-group>. <article-title>Balance control via tactile biofeedback in children with cerebral palsy</article-title>. <source>Acta of Bioeng Biomech</source>. (<year>2024</year>) <volume>25</volume>(<issue>1</issue>):<fpage>161</fpage>&#x2013;<lpage>71</lpage>. <pub-id pub-id-type="doi">10.37190/abb-02245-2023-03</pub-id></mixed-citation></ref>
<ref id="B31"><label>31.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Elnaggar</surname> <given-names>RK</given-names></name></person-group>. <article-title>Impact of simultaneous feedback augmentation and real time treadmill training on gait in diplegic children</article-title>. <source>Indian J Physiother Occup Ther Int J</source>. (<year>2014</year>) <volume>8</volume>(<issue>4</issue>):<fpage>253</fpage>. <pub-id pub-id-type="doi">10.5958/0973-5674.2014.00047.1</pub-id></mixed-citation></ref>
<ref id="B32"><label>32.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hamed</surname> <given-names>NS</given-names></name> <name><surname>Abd-Elwahab</surname> <given-names>MS</given-names></name></person-group>. <article-title>Pedometer-based gait training in children with spastic hemiparetic cerebral palsy: a randomized controlled study</article-title>. <source>Clin Rehabil</source>. (<year>2011</year>) <volume>25</volume>(<issue>2</issue>):<fpage>157</fpage>&#x2013;<lpage>65</lpage>. <pub-id pub-id-type="doi">10.1177/0269215510382147</pub-id><pub-id pub-id-type="pmid">20943714</pub-id></mixed-citation></ref>
<ref id="B33"><label>33.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Nagy</surname> <given-names>MAESM</given-names></name> <name><surname>Eltohamy</surname> <given-names>AM</given-names></name> <name><surname>Salem</surname> <given-names>NEM</given-names></name></person-group>. <article-title>Influence of rhythmic auditory feedback on gait in hemiparetic children</article-title>. <source>J Med Sci</source>. (<year>2020</year>) <volume>40</volume>(<issue>1</issue>):<fpage>1</fpage>&#x2013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.4103/JMEDSCI.JMEDSCI_57_19</pub-id></mixed-citation></ref>
<ref id="B34"><label>34.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Guinet</surname> <given-names>A-L</given-names></name> <name><surname>Bouyer</surname> <given-names>G</given-names></name> <name><surname>Otmane</surname> <given-names>S</given-names></name> <name><surname>Desailly</surname> <given-names>E</given-names></name></person-group>. <article-title>Visual feedback in augmented reality to walk at predefined speed cross-sectional study including children with cerebral palsy</article-title>. <source>IEEE Trans Neural Syst Rehabil Eng</source>. (<year>2022</year>) <volume>30</volume>:<fpage>2322</fpage>&#x2013;<lpage>31</lpage>. <pub-id pub-id-type="doi">10.1109/TNSRE.2022.3198243</pub-id><pub-id pub-id-type="pmid">35951576</pub-id></mixed-citation></ref>
<ref id="B35"><label>35.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>van Gelder</surname> <given-names>L</given-names></name> <name><surname>Booth</surname> <given-names>ATC</given-names></name> <name><surname>van de Port</surname> <given-names>I</given-names></name> <name><surname>Buizer</surname> <given-names>AI</given-names></name> <name><surname>Harlaar</surname> <given-names>J</given-names></name> <name><surname>van der Krogt</surname> <given-names>MM</given-names></name></person-group>. <article-title>Real-time feedback to improve gait in children with cerebral palsy</article-title>. <source>Gait Post</source>. (<year>2017</year>) <volume>52</volume>:<fpage>76</fpage>&#x2013;<lpage>82</lpage>. <pub-id pub-id-type="doi">10.1016/J.GAITPOST.2016.11.021</pub-id></mixed-citation></ref>
<ref id="B36"><label>36.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Flux</surname> <given-names>E</given-names></name> <name><surname>Bar-On</surname> <given-names>L</given-names></name> <name><surname>Buizer</surname> <given-names>AI</given-names></name> <name><surname>Harlaar</surname> <given-names>J</given-names></name> <name><surname>van der Krogt</surname> <given-names>MM</given-names></name></person-group>. <article-title>Electromyographic biofeedback-driven gaming to alter calf muscle activation during gait in children with spastic cerebral palsy</article-title>. <source>Gait and Posture</source>. (<year>2023</year>) <volume>102</volume>:<fpage>10</fpage>&#x2013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1016/J.GAITPOST.2023.02.012</pub-id><pub-id pub-id-type="pmid">36870265</pub-id></mixed-citation></ref>
<ref id="B37"><label>37.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hussein</surname> <given-names>ZA</given-names></name> <name><surname>Salem</surname> <given-names>IA</given-names></name> <name><surname>Ali</surname> <given-names>MS</given-names></name></person-group>. <article-title>Effect of simultaneous proprioceptive-visual feedback on gait of children with spastic diplegic cerebral palsy</article-title>. <source>J Musculoskelet Neuronal Interact</source>. (<year>2019</year>) <volume>19</volume>(<issue>4</issue>):<fpage>500</fpage>&#x2013;<lpage>6</lpage>. <pub-id pub-id-type="pmid">31789301</pub-id></mixed-citation></ref>
<ref id="B38"><label>38.</label><mixed-citation publication-type="book"><person-group person-group-type="author"><name><surname>Jiang</surname> <given-names>A</given-names></name></person-group>. <source>The Effect of Rhythmic Auditory Stimulation on Gait in Young Children with Spastic Cerebral Palsy</source>. <publisher-loc>Miami</publisher-loc>: <publisher-name>University of Miami</publisher-name> (<year>2013</year>). <comment>Available online at:</comment> <ext-link ext-link-type="uri" xlink:href="https://scholarship.miami.edu/esploro/outputs/graduate/The-Effect-of-Rhythmic-Auditory-Stimulation/991031447174902976">https://scholarship.miami.edu/esploro/outputs/graduate/The-Effect-of-Rhythmic-Auditory-Stimulation/991031447174902976</ext-link> <comment>(Accessed June 20, 2024)</comment>.</mixed-citation></ref>
<ref id="B39"><label>39.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Gagliardi</surname> <given-names>C</given-names></name> <name><surname>Turconi</surname> <given-names>AC</given-names></name> <name><surname>Biffi</surname> <given-names>E</given-names></name> <name><surname>Maghini</surname> <given-names>C</given-names></name> <name><surname>Marelli</surname> <given-names>A</given-names></name> <name><surname>Cesareo</surname> <given-names>A</given-names></name><etal/></person-group> <article-title>Immersive virtual reality to improve walking abilities in cerebral palsy: a pilot study</article-title>. <source>Ann Biomed Eng</source>. (<year>2018</year>) <volume>46</volume>(<issue>9</issue>):<fpage>1376</fpage>&#x2013;<lpage>84</lpage>. <pub-id pub-id-type="doi">10.1007/s10439-018-2039-1</pub-id><pub-id pub-id-type="pmid">29704186</pub-id></mixed-citation></ref>
<ref id="B40"><label>40.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Schoenmaker</surname> <given-names>J</given-names></name> <name><surname>Houdijk</surname> <given-names>H</given-names></name> <name><surname>Steenbergen</surname> <given-names>B</given-names></name> <name><surname>Reinders-Messelink</surname> <given-names>HA</given-names></name> <name><surname>Schoemaker</surname> <given-names>MM</given-names></name></person-group>. <article-title>Effectiveness of different extrinsic feedback forms on motor learning in children with cerebral palsy: a systematic review</article-title>. <source>Disabil Rehabil</source>. (<year>2023</year>) <volume>45</volume>(<issue>8</issue>):<fpage>1271</fpage>&#x2013;<lpage>84</lpage>. <pub-id pub-id-type="doi">10.1080/09638288.2022.2060333</pub-id><pub-id pub-id-type="pmid">35416108</pub-id></mixed-citation></ref>
<ref id="B41"><label>41.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Flodmark</surname> <given-names>A</given-names></name></person-group>. <article-title>Augmented auditory feedback as an aid in gait training of the cerebral-palsied child</article-title>. <source>Dev Med Child Neurol</source>. (<year>1986</year>) <volume>28</volume>(<issue>2</issue>):<fpage>147</fpage>&#x2013;<lpage>55</lpage>. <pub-id pub-id-type="doi">10.1111/j.1469-8749.1986.tb03848.x</pub-id><pub-id pub-id-type="pmid">3709983</pub-id></mixed-citation></ref>
<ref id="B42"><label>42.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ko</surname> <given-names>J</given-names></name> <name><surname>Kim</surname> <given-names>M</given-names></name></person-group>. <article-title>Reliability and responsiveness of the gross motor function measure-88 in children with cerebral palsy</article-title>. <source>Phys Ther</source>. (<year>2013</year>) <volume>93</volume>(<issue>3</issue>):<fpage>393</fpage>&#x2013;<lpage>400</lpage>. <pub-id pub-id-type="doi">10.2522/PTJ.20110374</pub-id><pub-id pub-id-type="pmid">23139425</pub-id></mixed-citation></ref>
<ref id="B43"><label>43.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Russell</surname> <given-names>DJ</given-names></name> <name><surname>Rosenbaum</surname> <given-names>PL</given-names></name> <name><surname>Cadman</surname> <given-names>DT</given-names></name> <name><surname>Gowland</surname> <given-names>C</given-names></name> <name><surname>Hardy</surname> <given-names>S</given-names></name> <name><surname>Jarvis</surname> <given-names>S</given-names></name></person-group>. <article-title>The gross motor function measure: a means to evaluate the effects of physical therapy</article-title>. <source>Dev Med Child Neurol</source>. (<year>1989</year>) <volume>31</volume>(<issue>3</issue>):<fpage>341</fpage>&#x2013;<lpage>52</lpage>. <pub-id pub-id-type="doi">10.1111/J.1469-8749.1989.TB04003.X</pub-id><pub-id pub-id-type="pmid">2753238</pub-id></mixed-citation></ref>
<ref id="B44"><label>44.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>van der Krogt</surname> <given-names>MM</given-names></name> <name><surname>Sloot</surname> <given-names>LH</given-names></name> <name><surname>Harlaar</surname> <given-names>J</given-names></name></person-group>. <article-title>Overground versus self-paced treadmill walking in a virtual environment in children with cerebral palsy</article-title>. <source>Gait Posture</source>. (<year>2014</year>) <volume>40</volume>(<issue>4</issue>):<fpage>587</fpage>&#x2013;<lpage>93</lpage>. <pub-id pub-id-type="doi">10.1016/J.GAITPOST.2014.07.003</pub-id><pub-id pub-id-type="pmid">25065627</pub-id></mixed-citation></ref>
<ref id="B45"><label>45.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>van der Krogt</surname> <given-names>MM</given-names></name> <name><surname>Sloot</surname> <given-names>LH</given-names></name> <name><surname>Buizer</surname> <given-names>AI</given-names></name> <name><surname>Harlaar</surname> <given-names>J</given-names></name></person-group>. <article-title>Kinetic comparison of walking on a treadmill versus over ground in children with cerebral palsy</article-title>. <source>J Biomech</source>. (<year>2015</year>) <volume>48</volume>(<issue>13</issue>):<fpage>3577</fpage>&#x2013;<lpage>83</lpage>. <pub-id pub-id-type="doi">10.1016/J.JBIOMECH.2015.07.046</pub-id><pub-id pub-id-type="pmid">26315918</pub-id></mixed-citation></ref>
<ref id="B46"><label>46.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Wang</surname> <given-names>TM</given-names></name> <name><surname>Huang</surname> <given-names>H-P</given-names></name> <name><surname>Li</surname> <given-names>J-D</given-names></name> <name><surname>Hong</surname> <given-names>S-W</given-names></name> <name><surname>Lo</surname> <given-names>W-C</given-names></name> <name><surname>Lu</surname> <given-names>T-W</given-names></name></person-group>. <article-title>Leg and joint stiffness in children with spastic diplegic cerebral palsy during level walking</article-title>. <source>PLoS One</source>. (<year>2015</year>) <volume>10</volume>:<fpage>12</fpage>. <pub-id pub-id-type="doi">10.1371/JOURNAL.PONE.0143967</pub-id></mixed-citation></ref>
<ref id="B47"><label>47.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Thompson</surname> <given-names>AK</given-names></name> <name><surname>Chen</surname> <given-names>XY</given-names></name> <name><surname>Wolpaw</surname> <given-names>JR</given-names></name></person-group>. <article-title>Acquisition of a simple motor skill: task-dependent adaptation plus long-term change in the human soleus H-reflex</article-title>. <source>J Neurosci</source>. (<year>2009</year>) <volume>29</volume>(<issue>18</issue>):<fpage>5784</fpage>&#x2013;<lpage>92</lpage>. <pub-id pub-id-type="doi">10.1523/JNEUROSCI.4326-08.2009</pub-id><pub-id pub-id-type="pmid">19420246</pub-id></mixed-citation></ref>
<ref id="B48"><label>48.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Thompson</surname> <given-names>AK</given-names></name> <name><surname>Wolpaw</surname> <given-names>JR</given-names></name></person-group>. <article-title>Restoring walking after spinal cord injury: operant conditioning of spinal reflexes can help</article-title>. <source>Neuroscientist</source>. (<year>2015</year>) <volume>21</volume>(<issue>2</issue>):<fpage>203</fpage>&#x2013;<lpage>15</lpage>. <pub-id pub-id-type="doi">10.1177/1073858414527541</pub-id><pub-id pub-id-type="pmid">24636954</pub-id></mixed-citation></ref>
<ref id="B49"><label>49.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Galli</surname> <given-names>J</given-names></name> <name><surname>Loi</surname> <given-names>E</given-names></name> <name><surname>Molinaro</surname> <given-names>A</given-names></name> <name><surname>Calza</surname> <given-names>S</given-names></name> <name><surname>Franzoni</surname> <given-names>A</given-names></name> <name><surname>Micheletti</surname> <given-names>S</given-names></name><etal/></person-group> <article-title>Age-Related effects on the Spectrum of cerebral visual impairment in children with cerebral palsy</article-title>. <source>Front Hum Neurosci</source>. (<year>2022</year>) <volume>16</volume>:<fpage>750464</fpage>. <pub-id pub-id-type="doi">10.3389/fnhum.2022.750464</pub-id><pub-id pub-id-type="pmid">35308614</pub-id></mixed-citation></ref>
<ref id="B50"><label>50.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Liu</surname> <given-names>M</given-names></name> <name><surname>Zhou</surname> <given-names>K</given-names></name> <name><surname>Chen</surname> <given-names>Y</given-names></name> <name><surname>Zhou</surname> <given-names>L</given-names></name> <name><surname>Bao</surname> <given-names>D</given-names></name> <name><surname>Zhou</surname> <given-names>J</given-names></name></person-group>. <article-title>Is virtual reality training more effective than traditional physical training on balance and functional mobility in healthy older adults? A systematic review and meta-analysis</article-title>. <source>Front Hum Neurosci</source>. (<year>2022</year>) <volume>16</volume>:<fpage>843481</fpage>. <pub-id pub-id-type="doi">10.3389/fnhum.2022.843481</pub-id><pub-id pub-id-type="pmid">35399351</pub-id></mixed-citation></ref>
<ref id="B51"><label>51.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Levin</surname> <given-names>I</given-names></name> <name><surname>Lewek</surname> <given-names>MD</given-names></name> <name><surname>Feasel</surname> <given-names>J</given-names></name> <name><surname>Thorpe</surname> <given-names>DE</given-names></name></person-group>. <article-title>Gait training with visual feedback and proprioceptive input to reduce gait asymmetry in adults with cerebral palsy: a case series</article-title>. <source>Pediatr Phys Ther</source>. (<year>2017</year>) <volume>29</volume>(<issue>2</issue>):<fpage>138</fpage>&#x2013;<lpage>45</lpage>. <pub-id pub-id-type="doi">10.1097/PEP.0000000000000362</pub-id><pub-id pub-id-type="pmid">28350769</pub-id></mixed-citation></ref>
<ref id="B52"><label>52.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rauchenzauner</surname> <given-names>M</given-names></name> <name><surname>Schiller</surname> <given-names>K</given-names></name> <name><surname>Honold</surname> <given-names>M</given-names></name> <name><surname>Baldissera</surname> <given-names>I</given-names></name> <name><surname>Biedermann</surname> <given-names>R</given-names></name> <name><surname>Tschiderer</surname> <given-names>B</given-names></name><etal/></person-group> <article-title>Visual impairment and functional classification in children with cerebral palsy</article-title>. <source>Neuropediatrics</source>. (<year>2021</year>) <volume>52</volume>(<issue>5</issue>):<fpage>383</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1055/s-0040-1722679</pub-id><pub-id pub-id-type="pmid">33511594</pub-id></mixed-citation></ref>
<ref id="B53"><label>53.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Striber</surname> <given-names>N</given-names></name> <name><surname>Vulin</surname> <given-names>K</given-names></name> <name><surname>&#x0110;akovi&#x0107;</surname> <given-names>I</given-names></name> <name><surname>Prv&#x010D;i&#x0107;</surname> <given-names>I</given-names></name> <name><surname>&#x0110;uranovi&#x0107;,</surname> <given-names>V</given-names></name> <name><surname>Cerovski</surname> <given-names>B</given-names></name><etal/></person-group> <article-title>Visual impairment in children with cerebral palsy: croatian population-based study for birth years 2003&#x2013;2008</article-title>. <source>Croat Med J</source>. (<year>2019</year>) <volume>60</volume>(<issue>5</issue>):<fpage>414</fpage>&#x2013;<lpage>20</lpage>. <pub-id pub-id-type="doi">10.3325/cmj.2019.60.414</pub-id><pub-id pub-id-type="pmid">31686455</pub-id></mixed-citation></ref>
<ref id="B54"><label>54.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bonnyaud</surname> <given-names>C</given-names></name> <name><surname>Pradon</surname> <given-names>D</given-names></name> <name><surname>Zory</surname> <given-names>R</given-names></name> <name><surname>Bensmail</surname> <given-names>D</given-names></name> <name><surname>Vuillerme</surname> <given-names>N</given-names></name> <name><surname>Roche</surname> <given-names>N</given-names></name></person-group>. <article-title>Does a single gait training session performed either overground or on a treadmill induce specific short-term effects on gait parameters in patients with hemiparesis? A randomized controlled study</article-title>. <source>Top Stroke Rehabil</source>. (<year>2013</year>) <volume>20</volume>(<issue>6</issue>):<fpage>509</fpage>&#x2013;<lpage>18</lpage>. <pub-id pub-id-type="doi">10.1310/TSR2006-509</pub-id><pub-id pub-id-type="pmid">24273298</pub-id></mixed-citation></ref>
<ref id="B55"><label>55.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Krewer</surname> <given-names>C</given-names></name> <name><surname>Rie&#x00DF;</surname> <given-names>K</given-names></name> <name><surname>Bergmann</surname> <given-names>J</given-names></name> <name><surname>M&#x00FC;ller</surname> <given-names>F</given-names></name> <name><surname>Jahn</surname> <given-names>K</given-names></name> <name><surname>Koenig</surname> <given-names>E</given-names></name></person-group>. <article-title>Immediate effectiveness of single-session therapeutic interventions in pusher behaviour</article-title>. <source>Gait Posture</source>. (<year>2013</year>) <volume>37</volume>(<issue>2</issue>):<fpage>246</fpage>&#x2013;<lpage>50</lpage>. <pub-id pub-id-type="doi">10.1016/J.GAITPOST.2012.07.014</pub-id><pub-id pub-id-type="pmid">22889929</pub-id></mixed-citation></ref>
<ref id="B56"><label>56.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Salmoni</surname> <given-names>AW</given-names></name> <name><surname>Schmidt</surname> <given-names>RA</given-names></name> <name><surname>Walter</surname> <given-names>CB</given-names></name></person-group>. <article-title>Knowledge of results and motor learning: a review and critical reappraisal</article-title>. <source>Psychol Bull</source>. (<year>1984</year>) <volume>95</volume>(<issue>3</issue>):<fpage>355</fpage>&#x2013;<lpage>86</lpage>. <pub-id pub-id-type="doi">10.1037/0033-2909.95.3.355</pub-id><pub-id pub-id-type="pmid">6399752</pub-id></mixed-citation></ref>
<ref id="B57"><label>57.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Wulf</surname> <given-names>G</given-names></name> <name><surname>Shea</surname> <given-names>CH</given-names></name></person-group>. <article-title>Principles derived from the study of simple skills do not generalize to complex skill learning</article-title>. <source>Psychonom Bull Rev</source>. (<year>2002</year>) <volume>9</volume>(<issue>2</issue>):<fpage>185</fpage>&#x2013;<lpage>211</lpage>. <pub-id pub-id-type="doi">10.3758/bf03196276</pub-id></mixed-citation></ref>
<ref id="B58"><label>58.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bax</surname> <given-names>M</given-names></name> <name><surname>Goldstein</surname> <given-names>M</given-names></name> <name><surname>Rosenbaum</surname> <given-names>P</given-names></name> <name><surname>Leviton</surname> <given-names>A</given-names></name> <name><surname>Paneth</surname> <given-names>N</given-names></name> <name><surname>Dan</surname> <given-names>B</given-names></name><etal/></person-group> <article-title>Proposed definition and classification of cerebral palsy, April 2005</article-title>. <source>Dev Med Child Neurol</source>. (<year>2005</year>) <volume>47</volume>(<issue>8</issue>):<fpage>571</fpage>&#x2013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1017/s001216220500112x</pub-id><pub-id pub-id-type="pmid">16108461</pub-id></mixed-citation></ref>
<ref id="B59"><label>59.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Graham</surname> <given-names>HK</given-names></name> <name><surname>Rosenbaum</surname> <given-names>P</given-names></name> <name><surname>Paneth</surname> <given-names>N</given-names></name> <name><surname>Dan</surname> <given-names>B</given-names></name> <name><surname>Lin</surname> <given-names>JP</given-names></name> <name><surname>Damiano</surname> <given-names>DL</given-names></name><etal/></person-group> <article-title>Cerebral palsy</article-title>. <source>Nat Rev Dis Primers</source>. (<year>2016</year>) <volume>2</volume>:<fpage>15082</fpage>. <pub-id pub-id-type="doi">10.1038/nrdp.2015.82</pub-id><pub-id pub-id-type="pmid">27188686</pub-id></mixed-citation></ref>
<ref id="B60"><label>60.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Palisano</surname> <given-names>R</given-names></name> <name><surname>Rosenbaum</surname> <given-names>P</given-names></name> <name><surname>Walter</surname> <given-names>S</given-names></name> <name><surname>Russell</surname> <given-names>D</given-names></name> <name><surname>Wood</surname> <given-names>E</given-names></name> <name><surname>Galuppi</surname> <given-names>B</given-names></name></person-group>. <article-title>Development and reliability of a system to classify gross motor function in children with cerebral palsy</article-title>. <source>Dev Med Child Neurol</source>. (<year>1997</year>) <volume>39</volume>(<issue>4</issue>):<fpage>214</fpage>&#x2013;<lpage>23</lpage>. <pub-id pub-id-type="doi">10.1111/j.1469-8749.1997.tb07414.x</pub-id><pub-id pub-id-type="pmid">9183258</pub-id></mixed-citation></ref>
<ref id="B61"><label>61.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sadowska</surname> <given-names>M</given-names></name> <name><surname>Sarecka-Hujar</surname> <given-names>B</given-names></name> <name><surname>Kopyta</surname> <given-names>I</given-names></name></person-group>. <article-title>Cerebral palsy: current opinions on definition, epidemiology, risk factors, classification and treatment options</article-title>. <source>Neuropsychiatr Dis Treat</source>. (<year>2020</year>) <volume>16</volume>:<fpage>1505</fpage>&#x2013;<lpage>18</lpage>. <pub-id pub-id-type="doi">10.2147/NDT.S235165</pub-id><pub-id pub-id-type="pmid">32606703</pub-id></mixed-citation></ref>
<ref id="B62"><label>62.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kirby</surname> <given-names>RS</given-names></name> <name><surname>Wingate</surname> <given-names>MS</given-names></name> <name><surname>Van Naarden Braun</surname> <given-names>K</given-names></name> <name><surname>Doernberg</surname> <given-names>NS</given-names></name> <name><surname>Arneson</surname> <given-names>CL</given-names></name> <name><surname>Benedict</surname> <given-names>RE</given-names></name><etal/></person-group> <article-title>Prevalence and functioning of children with cerebral palsy in four areas of the United States in 2006: a report from the autism and developmental disabilities monitoring network</article-title>. <source>Res Dev Disabil</source>. (<year>2011</year>) <volume>32</volume>(<issue>2</issue>):<fpage>462</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1016/j.ridd.2010.12.042</pub-id><pub-id pub-id-type="pmid">21273041</pub-id></mixed-citation></ref>
<ref id="B63"><label>63.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Beltrame</surname> <given-names>G</given-names></name> <name><surname>Scano</surname> <given-names>A</given-names></name> <name><surname>Marino</surname> <given-names>G</given-names></name> <name><surname>Peccati</surname> <given-names>A</given-names></name> <name><surname>Molinari Tosatti</surname> <given-names>L</given-names></name> <name><surname>Portinaro</surname> <given-names>N</given-names></name></person-group>. <article-title>Recent developments in muscle synergy analysis in young people with neurodevelopmental diseases: a systematic review</article-title>. <source>Front Bioeng Biotechnol</source>. (<year>2023</year>) <volume>11</volume>:<fpage>1145937</fpage>. <pub-id pub-id-type="doi">10.3389/fbioe.2023.1145937</pub-id><pub-id pub-id-type="pmid">37180039</pub-id></mixed-citation></ref>
<ref id="B64"><label>64.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Moinuddin</surname> <given-names>A</given-names></name> <name><surname>Goel</surname> <given-names>A</given-names></name> <name><surname>Sethi</surname> <given-names>Y</given-names></name></person-group>. <article-title>The role of augmented feedback on motor learning: a systematic review</article-title>. <source>Cureus</source>. (<year>2021</year>) <volume>13</volume>(<issue>11</issue>):<fpage>e19695</fpage>. <pub-id pub-id-type="doi">10.7759/cureus.19695</pub-id><pub-id pub-id-type="pmid">34976475</pub-id></mixed-citation></ref>
<ref id="B65"><label>65.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>W&#x00E4;lchli</surname> <given-names>M</given-names></name> <name><surname>Ruffieux</surname> <given-names>J</given-names></name> <name><surname>Bourquin</surname> <given-names>Y</given-names></name> <name><surname>Keller</surname> <given-names>M</given-names></name> <name><surname>Taube</surname> <given-names>W</given-names></name></person-group>. <article-title>Maximizing performance: augmented feedback, focus of attention, and/or reward?</article-title> <source>Med Sci Sports Exerc</source>. (<year>2016</year>) <volume>48</volume>(<issue>4</issue>):<fpage>714</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1249/MSS.0000000000000818</pub-id></mixed-citation></ref>
<ref id="B66"><label>66.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Merians</surname> <given-names>AS</given-names></name> <name><surname>Jack</surname> <given-names>D</given-names></name> <name><surname>Boian</surname> <given-names>R</given-names></name> <name><surname>Tremaine</surname> <given-names>M</given-names></name> <name><surname>Burdea</surname> <given-names>GC</given-names></name> <name><surname>Adamovich</surname> <given-names>SV</given-names></name><etal/></person-group> <article-title>Virtual reality-augmented rehabilitation for patients following stroke</article-title>. <source>Phys Ther</source>. (<year>2002</year>) <volume>82</volume>(<issue>9</issue>):<fpage>898</fpage>&#x2013;<lpage>915</lpage>. <pub-id pub-id-type="doi">10.1093/ptj/82.9.898</pub-id><pub-id pub-id-type="pmid">12201804</pub-id></mixed-citation></ref>
<ref id="B67"><label>67.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kleim</surname> <given-names>JA</given-names></name> <name><surname>Jones</surname> <given-names>TA</given-names></name></person-group>. <article-title>Principles of experience-dependent neural plasticity: implications for rehabilitation after brain damage</article-title>. <source>J Speech Lang Hear Res</source>. (<year>2008</year>) <volume>51</volume>(<issue>1</issue>):<fpage>S225</fpage>&#x2013;<lpage>39</lpage>. <pub-id pub-id-type="doi">10.1044/1092-4388(2008/018)</pub-id><pub-id pub-id-type="pmid">18230848</pub-id></mixed-citation></ref>
<ref id="B68"><label>68.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rethlefsen</surname> <given-names>SA</given-names></name> <name><surname>Blumstein</surname> <given-names>G</given-names></name> <name><surname>Kay</surname> <given-names>RM</given-names></name> <name><surname>Dorey</surname> <given-names>F</given-names></name> <name><surname>Wren</surname> <given-names>TA</given-names></name></person-group>. <article-title>Prevalence of specific gait abnormalities in children with cerebral palsy revisited: influence of age, prior surgery, and gross motor function classification system level</article-title>. <source>Dev Med Child Neurol</source>. (<year>2017</year>) <volume>59</volume>(<issue>1</issue>):<fpage>79</fpage>&#x2013;<lpage>88</lpage>. <pub-id pub-id-type="doi">10.1111/dmcn.13205</pub-id><pub-id pub-id-type="pmid">27421715</pub-id></mixed-citation></ref>
<ref id="B69"><label>69.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kim</surname> <given-names>Y</given-names></name> <name><surname>Bulea</surname> <given-names>TC</given-names></name> <name><surname>Damiano</surname> <given-names>DL</given-names></name></person-group>. <article-title>Greater reliance on cerebral palsy-specific muscle synergies during gait relates to poorer temporal-spatial performance measures</article-title>. <source>Front Physiol</source>. (<year>2021</year>) <volume>12</volume>:<fpage>630627</fpage>. <pub-id pub-id-type="doi">10.3389/fphys.2021.630627</pub-id><pub-id pub-id-type="pmid">33708139</pub-id></mixed-citation></ref>
<ref id="B70"><label>70.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bjornson</surname> <given-names>KF</given-names></name> <name><surname>Zhou</surname> <given-names>C</given-names></name> <name><surname>Stevenson</surname> <given-names>RD</given-names></name> <name><surname>Christakis</surname> <given-names>D</given-names></name></person-group>. <article-title>Relation of stride activity and participation in mobility-based life habits among children with cerebral palsy</article-title>. <source>Arch Phys Med Rehabil</source>. (<year>2014</year>) <volume>95</volume>(<issue>2</issue>):<fpage>360</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1016/j.apmr.2013.10.022</pub-id><pub-id pub-id-type="pmid">24231402</pub-id></mixed-citation></ref>
<ref id="B71"><label>71.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Qian</surname> <given-names>G</given-names></name> <name><surname>Cai</surname> <given-names>X</given-names></name> <name><surname>Xu</surname> <given-names>K</given-names></name> <name><surname>Tian</surname> <given-names>H</given-names></name> <name><surname>Meng</surname> <given-names>Q</given-names></name> <name><surname>Ossowski</surname> <given-names>Z</given-names></name><etal/></person-group> <article-title>Which gait training intervention can most effectively improve gait ability in patients with cerebral palsy? A systematic review and network meta-analysis</article-title>. <source>Front Neurol</source>. (<year>2023</year>) <volume>13</volume>:<fpage>1005485</fpage>. <pub-id pub-id-type="doi">10.3389/fneur.2022.1005485</pub-id><pub-id pub-id-type="pmid">36703638</pub-id></mixed-citation></ref>
<ref id="B72"><label>72.</label><mixed-citation publication-type="other"><person-group person-group-type="author"><name><surname>Jiang</surname></name></person-group>. <article-title>This is a thesis of the University of Miami</article-title> (<year>2018</year>). <comment>Available online at:</comment> <ext-link ext-link-type="uri" xlink:href="https://scholarship.miami.edu/esploro/outputs/graduate/The-Effect-of-Rhythmic-Auditory-Stimulation/991031447174902976">https://scholarship.miami.edu/esploro/outputs/graduate/The-Effect-of-Rhythmic-Auditory-Stimulation/991031447174902976</ext-link> [<comment>Accessed (2024)</comment>]</mixed-citation></ref>
<ref id="B73"><label>73.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kerr</surname> <given-names>C</given-names></name> <name><surname>Parkes</surname> <given-names>J</given-names></name> <name><surname>Stevenson</surname> <given-names>M</given-names></name> <name><surname>Cosgrove</surname> <given-names>AP</given-names></name> <name><surname>McDowell</surname> <given-names>BC</given-names></name></person-group>. <article-title>Energy efficiency in gait, activity, participation, and health status in children with cerebral palsy</article-title>. <source>Dev Med Child Neurol</source>. (<year>2008</year>) <volume>50</volume>(<issue>3</issue>):<fpage>204</fpage>&#x2013;<lpage>10</lpage>. <pub-id pub-id-type="doi">10.1111/j.1469-8749.2008.02030.x</pub-id><pub-id pub-id-type="pmid">18215192</pub-id></mixed-citation></ref>
<ref id="B74"><label>74.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Morgan</surname> <given-names>P</given-names></name> <name><surname>McGinley</surname> <given-names>J</given-names></name></person-group>. <article-title>Gait function and decline in adults with cerebral palsy: a systematic review</article-title>. <source>Disabil Rehabil</source>. (<year>2014</year>) <volume>36</volume>(<issue>1</issue>):<fpage>1</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.3109/09638288.2013.775359</pub-id><pub-id pub-id-type="pmid">23594053</pub-id></mixed-citation></ref>
<ref id="B75"><label>75.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sutherland</surname> <given-names>D</given-names></name></person-group>. <article-title>The development of mature gait</article-title>. <source>Gait Posture</source>. (<year>1997</year>) <volume>6</volume>(<issue>2</issue>):<fpage>163</fpage>&#x2013;<lpage>70</lpage>. <pub-id pub-id-type="doi">10.1016/S0966-6362(97)00029-5</pub-id></mixed-citation></ref>
<ref id="B76"><label>76.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bottcher</surname> <given-names>L</given-names></name></person-group>. <article-title>Children with spastic cerebral palsy, their cognitive functioning, and social participation: a review</article-title>. <source>Child Neuropsychol</source>. (<year>2010</year>) <volume>16</volume>(<issue>3</issue>):<fpage>209</fpage>&#x2013;<lpage>28</lpage>. <pub-id pub-id-type="doi">10.1080/09297040903559630</pub-id><pub-id pub-id-type="pmid">20209416</pub-id></mixed-citation></ref>
<ref id="B77"><label>77.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Krishnan</surname> <given-names>C</given-names></name> <name><surname>Washabaugh</surname> <given-names>EP</given-names></name> <name><surname>Reid</surname> <given-names>CE</given-names></name> <name><surname>Althoen</surname> <given-names>MM</given-names></name> <name><surname>Ranganathan</surname> <given-names>R</given-names></name></person-group>. <article-title>Learning new gait patterns: age-related differences in skill acquisition and interlimb transfer</article-title>. <source>Exp Gerontol</source>. (<year>2018</year>) <volume>111</volume>:<fpage>45</fpage>&#x2013;<lpage>52</lpage>. <pub-id pub-id-type="doi">10.1016/j.exger.2018.07.001</pub-id><pub-id pub-id-type="pmid">29981399</pub-id></mixed-citation></ref></ref-list>
<fn-group>
<fn id="n1" fn-type="custom" custom-type="edited-by"><p>Edited by: <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/1040550/overview">Tsan-Hon Liou</ext-link>, Taipei Medical University, Taiwan</p></fn>
<fn id="n2" fn-type="custom" custom-type="reviewed-by"><p>Reviewed by: <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/655532/overview">Ad&#x00E9;rito Ricardo Duarte Seixas</ext-link>, Escola Superior de Sa&#x00FA;de Fernando Pessoa, Portugal</p>
<p><ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/2953862/overview">Andrea Vancetto Maglione</ext-link>, Universidade Cidade de S&#x00E3;o Paulo, Brazil</p></fn>
</fn-group>
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