<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3-mathml3.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.3" xml:lang="EN">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Public Health</journal-id>
<journal-title-group>
<journal-title>Frontiers in Public Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Public Health</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2296-2565</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpubh.2025.1746822</article-id>
<article-version article-version-type="Version of Record" vocab="NISO-RP-8-2008"/>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Original Research</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Utilization, user evaluation, and associated factors of Traditional Chinese Medicine techniques for insomnia symptoms among Chinese community-dwelling older adults: a cross-sectional study</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" equal-contrib="yes"><name><surname>Mo</surname> <given-names>Yun</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="author-notes" rid="fn0001"><sup>&#x2020;</sup></xref>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="investigation" vocab-term-identifier="https://credit.niso.org/contributor-roles/investigation/">Investigation</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Data curation" vocab-term-identifier="https://credit.niso.org/contributor-roles/data-curation/">Data curation</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Project administration" vocab-term-identifier="https://credit.niso.org/contributor-roles/project-administration/">Project administration</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Writing &#x2013; original draft" vocab-term-identifier="https://credit.niso.org/contributor-roles/writing-original-draft/">Writing &#x2013; original draft</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Funding acquisition" vocab-term-identifier="https://credit.niso.org/contributor-roles/funding-acquisition/">Funding acquisition</role>
</contrib>
<contrib contrib-type="author" equal-contrib="yes"><name><surname>Hu</surname> <given-names>Li</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="author-notes" rid="fn0001"><sup>&#x2020;</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/2029295"/>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="conceptualization" vocab-term-identifier="https://credit.niso.org/contributor-roles/conceptualization/">Conceptualization</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="validation" vocab-term-identifier="https://credit.niso.org/contributor-roles/validation/">Validation</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="methodology" vocab-term-identifier="https://credit.niso.org/contributor-roles/methodology/">Methodology</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Writing &#x2013; review &#x0026; editing" vocab-term-identifier="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing &#x2013; review &#x0026; editing</role>
</contrib>
<contrib contrib-type="author"><name><surname>Shen</surname> <given-names>Xi</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Writing &#x2013; review &#x0026; editing" vocab-term-identifier="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing &#x2013; review &#x0026; editing</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Formal analysis" vocab-term-identifier="https://credit.niso.org/contributor-roles/formal-analysis/">Formal analysis</role>
</contrib>
<contrib contrib-type="author"><name><surname>Zhang</surname> <given-names>Yi</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Writing &#x2013; review &#x0026; editing" vocab-term-identifier="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing &#x2013; review &#x0026; editing</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Formal analysis" vocab-term-identifier="https://credit.niso.org/contributor-roles/formal-analysis/">Formal analysis</role>
</contrib>
<contrib contrib-type="author"><name><surname>Li</surname> <given-names>Site</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="investigation" vocab-term-identifier="https://credit.niso.org/contributor-roles/investigation/">Investigation</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Writing &#x2013; review &#x0026; editing" vocab-term-identifier="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing &#x2013; review &#x0026; editing</role>
</contrib>
<contrib contrib-type="author"><name><surname>Peng</surname> <given-names>Jiaxiu</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Writing &#x2013; review &#x0026; editing" vocab-term-identifier="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing &#x2013; review &#x0026; editing</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="investigation" vocab-term-identifier="https://credit.niso.org/contributor-roles/investigation/">Investigation</role>
</contrib>
<contrib contrib-type="author"><name><surname>Long</surname> <given-names>Yuping</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="investigation" vocab-term-identifier="https://credit.niso.org/contributor-roles/investigation/">Investigation</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Writing &#x2013; review &#x0026; editing" vocab-term-identifier="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing &#x2013; review &#x0026; editing</role>
</contrib>
<contrib contrib-type="author"><name><surname>Wu</surname> <given-names>Xiangrong</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Writing &#x2013; review &#x0026; editing" vocab-term-identifier="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing &#x2013; review &#x0026; editing</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="investigation" vocab-term-identifier="https://credit.niso.org/contributor-roles/investigation/">Investigation</role>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Xu</surname> <given-names>Binbin</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="c001"><sup>&#x002A;</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/3281136"/>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="supervision" vocab-term-identifier="https://credit.niso.org/contributor-roles/supervision/">Supervision</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="methodology" vocab-term-identifier="https://credit.niso.org/contributor-roles/methodology/">Methodology</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="resources" vocab-term-identifier="https://credit.niso.org/contributor-roles/resources/">Resources</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Writing &#x2013; review &#x0026; editing" vocab-term-identifier="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing &#x2013; review &#x0026; editing</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="conceptualization" vocab-term-identifier="https://credit.niso.org/contributor-roles/conceptualization/">Conceptualization</role>
<role vocab="credit" vocab-identifier="https://credit.niso.org/" vocab-term="Funding acquisition" vocab-term-identifier="https://credit.niso.org/contributor-roles/funding-acquisition/">Funding acquisition</role>
</contrib>
</contrib-group>
<aff id="aff1"><label>1</label><institution>School of Nursing, Hunan University of Chinese Medicine</institution>, <city>Changsha</city>, <state>Hunan</state>, <country country="cn">China</country></aff>
<aff id="aff2"><label>2</label><institution>The Affiliated Hospital of Guizhou Medical University</institution>, <city>Guiyang</city>, <state>Guizhou</state>, <country country="cn">China</country></aff>
<author-notes>
<corresp id="c001"><label>&#x002A;</label>Correspondence: Binbin Xu, <email xlink:href="mailto:18273146689@163.com">18273146689@163.com</email></corresp>
<fn fn-type="equal" id="fn0001">
<label>&#x2020;</label>
<p>These authors have contributed equally to this work</p>
</fn>
</author-notes>
<pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-01-15">
<day>15</day>
<month>01</month>
<year>2026</year>
</pub-date>
<pub-date publication-format="electronic" date-type="collection">
<year>2025</year>
</pub-date>
<volume>13</volume>
<elocation-id>1746822</elocation-id>
<history>
<date date-type="received">
<day>15</day>
<month>11</month>
<year>2025</year>
</date>
<date date-type="rev-recd">
<day>17</day>
<month>12</month>
<year>2025</year>
</date>
<date date-type="accepted">
<day>29</day>
<month>12</month>
<year>2025</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2026 Mo, Hu, Shen, Zhang, Li, Peng, Long, Wu and Xu.</copyright-statement>
<copyright-year>2026</copyright-year>
<copyright-holder>Mo, Hu, Shen, Zhang, Li, Peng, Long, Wu and Xu</copyright-holder>
<license>
<ali:license_ref start_date="2026-01-15">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
<license-p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</license-p>
</license>
</permissions>
<abstract>
<sec>
<title>Background</title>
<p>Insomnia symptoms are common among older adults, and Traditional Chinese Medicine (TCM) techniques have shown benefits in relieving these symptoms. However, real-world evidence on their use, evaluation, and associated factors in community settings remains limited. This study aimed to describe TCM use and user evaluation for insomnia symptoms among community-dwelling older adults and to explore associated factors.</p>
</sec>
<sec>
<title>Methods</title>
<p>An exploratory cross-sectional survey was conducted from November 2024 to April 2025 in 15 communities in Changsha, China. Older adults (&#x2265;60&#x202F;years) with clinically significant insomnia symptoms (Insomnia Severity Index &#x2265;8) were recruited. Data were collected on TCM use, perceived satisfaction and effectiveness, and predisposing, enabling, and need-related factors based on the Andersen Behavioral Model. Logistic regression was used to identify associated factors.</p>
</sec>
<sec>
<title>Results</title>
<p>Among 311 participants, 51.1% reported using at least one TCM technique, most commonly tuina (71.1%) and moxibustion (69.8%). Satisfaction was generally high, though only 20.1&#x2013;28.3% were &#x201C;very satisfied&#x201D; and 22.6% perceived the interventions as &#x201C;highly effective.&#x201D; Four factors were significantly associated with TCM use: pre-retirement occupation and awareness of TCM techniques (predisposing), having relatives or friends engaged in TCM-related industries (enabling), and insomnia severity (need).</p>
</sec>
<sec>
<title>Conclusion</title>
<p>This study provides preliminary evidence on the real-world use of TCM techniques for insomnia symptoms among community- dwelling older adults. More than half of participants reported using at least one TCM technique, yet only a minority rated the TCM services as &#x201C;very satisfied&#x201D; or &#x201C;highly effective.&#x201D; Pre-retirement occupation, awareness of TCM techniques, having relatives or friends working in TCM-related industries, and insomnia severity were associated with TCM technique use. These findings may inform the design of culturally sensitive interventions to manage insomnia symptoms among community-dwelling older adults in similar contexts. Future research should further examine implementation quality and ways to improve both utilization and user satisfaction.</p>
</sec>
</abstract>
<kwd-group>
<kwd>Andersen Behavioral Model</kwd>
<kwd>community</kwd>
<kwd>healthcare utilization</kwd>
<kwd>insomnia symptoms</kwd>
<kwd>older adults</kwd>
<kwd>Traditional Chinese Medicine (TCM)</kwd>
</kwd-group>
<funding-group>
<funding-statement>The author(s) declared that financial support was received for this work and/or its publication. This study was supported by the 2024 University-level Undergraduate Innovation and Entrepreneurship Training Program of Hunan University of Chinese Medicine.</funding-statement>
</funding-group>
<counts>
<fig-count count="0"/>
<table-count count="4"/>
<equation-count count="1"/>
<ref-count count="43"/>
<page-count count="12"/>
<word-count count="7461"/>
</counts>
<custom-meta-group>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Aging and Public Health</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="sec1">
<label>1</label>
<title>Introduction</title>
<p>Insomnia disorder is the most common sleep&#x2013;wake disorder, defined by persistent difficulty initiating or maintaining sleep or experiencing early morning awakenings despite adequate opportunity for sleep, accompanied by clinically significant daytime impairment (<xref ref-type="bibr" rid="ref1">1</xref>, <xref ref-type="bibr" rid="ref2">2</xref>). Diagnostic guidelines specify that these symptoms must occur at least three nights per week and persist for at least 3&#x202F;months to confirm a diagnosis (<xref ref-type="bibr" rid="ref1">1</xref>, <xref ref-type="bibr" rid="ref3">3</xref>). Its prevalence increases with age (<xref ref-type="bibr" rid="ref1">1</xref>), posing a substantial public health challenge. Among adults aged &#x2265;60&#x202F;years, the prevalence of clinically diagnosed insomnia disorder ranges from 12 to 20% (<xref ref-type="bibr" rid="ref2">2</xref>), compared to 6&#x2013;10% in the general population (<xref ref-type="bibr" rid="ref1">1</xref>). This elevated risk is closely associated with age-related physiological changes, multimorbidity, decreased mobility, retirement, and reduced social interaction (<xref ref-type="bibr" rid="ref2">2</xref>).</p>
<p>The consequences of insomnia disorder extend far beyond nighttime sleep disturbance, affecting multiple health domains. Evidence indicates that insomnia disorder is a significant risk factor for hypertension, diabetes, obesity, and cardiovascular disease (<xref ref-type="bibr" rid="ref4 ref5 ref6">4&#x2013;6</xref>), as well as mood disorders such as depression and anxiety (<xref ref-type="bibr" rid="ref7">7</xref>, <xref ref-type="bibr" rid="ref8">8</xref>). A meta-analysis links it to an increased risk of cognitive decline and dementia (<xref ref-type="bibr" rid="ref9">9</xref>), while other studies associate it with falls (<xref ref-type="bibr" rid="ref10">10</xref>, <xref ref-type="bibr" rid="ref11">11</xref>), frailty (<xref ref-type="bibr" rid="ref12">12</xref>), reduced quality of life (<xref ref-type="bibr" rid="ref13">13</xref>), and increased healthcare utilization and costs (<xref ref-type="bibr" rid="ref14">14</xref>). Addressing insomnia in older adults is therefore essential to promote healthy aging and reduce societal disease burden.</p>
<p>Compared with insomnia disorder, insomnia symptoms&#x2014;frequent difficulty falling or staying asleep without meeting full diagnostic criteria&#x2014;are even more widespread. Globally, these symptoms affect 30&#x2013;48% of individuals aged &#x2265;60&#x202F;years (<xref ref-type="bibr" rid="ref2">2</xref>). In China, prevalence varies by measurement tool and setting. For example, a study showed that 33.9% of Chinese community-dwelling adults aged&#x2265;60&#x202F;years had insomnia symptoms, measured by the Pittsburgh Sleep Quality Index (<xref ref-type="bibr" rid="ref12">12</xref>). The prevalence of insomnia symptoms was 45.7% among rural Chinese older adults aged 60&#x202F;years and above, measured by the Insomnia Severity Index (ISI) (<xref ref-type="bibr" rid="ref15">15</xref>). These symptoms may persist for months or years, substantially increasing health risks even without a formal diagnosis. For instance, a longitudinal cohort study examined the trajectories of insomnia symptoms over 12&#x202F;months during a time of stress and uncertainty and found that insomnia symptoms demonstrated a high persistence rate of 54% over time; Only 10.05% of participants with insomnia symptoms at baseline remitted over 12&#x202F;months (<xref ref-type="bibr" rid="ref16">16</xref>). These findings underscore the critical need for timely management of insomnia symptoms, not just insomnia disorder.</p>
<p>Currently, cognitive behavioral therapy for insomnia (CBT-I) is the first-line treatment for insomnia across all age groups, while pharmacological therapies remain widely used (<xref ref-type="bibr" rid="ref17">17</xref>, <xref ref-type="bibr" rid="ref18">18</xref>). However, both approaches face major challenges in older adults. Although CBT-I is the gold standard, its clinical uptake is very low, ranging from 1 to 29% (<xref ref-type="bibr" rid="ref19">19</xref>). In China, its promotion is hindered by limited accessibility and acceptability: a severe shortage of qualified therapists (especially in primary care), cultural stigma toward psychological treatment, high costs, geographic disparities, and an underdeveloped mental health service system (<xref ref-type="bibr" rid="ref20">20</xref>, <xref ref-type="bibr" rid="ref21">21</xref>). Current hypnotics (Z-drugs, benzodiazepines, low-dose doxepin, suvorexant) carry notable risks in older adults; thus, short-term or intermittent use is advised (<xref ref-type="bibr" rid="ref22">22</xref>). Ramelteon may offer safer sleep-onset benefits but has limited efficacy for sleep maintenance, while melatonin is relatively safe but lacks robust safety data in older populations (<xref ref-type="bibr" rid="ref22">22</xref>, <xref ref-type="bibr" rid="ref23">23</xref>). Additionally, many older adults perceive insomnia as a &#x201C;normal&#x201D; part of aging and avoid professional care; only 2.1% of adults with insomnia symptoms sought sleep-related healthcare in the past year (<xref ref-type="bibr" rid="ref24">24</xref>). These structural and perceptual barriers highlight an urgent need for alternative, culturally acceptable, and scalable solutions, particularly in community settings.</p>
<p>Traditional Chinese Medicine (TCM) techniques, grounded in the principles of yin-yang balance, five elements, and holistic regulation, offer promising options for managing insomnia symptoms, especially among older adults in community settings (<xref ref-type="bibr" rid="ref25">25</xref>, <xref ref-type="bibr" rid="ref26">26</xref>). Common techniques&#x2014;such as acupuncture, tuina, moxibustion, auricular acupressure, and needle embedding&#x2014;are generally safe, low-cost, easy to administer, and culturally appropriate (<xref ref-type="bibr" rid="ref27">27</xref>). Randomized controlled trials and systematic reviews have provided preliminary evidence supporting their clinical effectiveness in improving sleep quality (<xref ref-type="bibr" rid="ref25 ref26 ref27 ref28 ref29 ref30">25&#x2013;30</xref>). However, existing research has largely focused on efficacy under controlled conditions, with little attention to real-world implementation. In particular, little is known about how older adults in community settings actually use different TCM techniques, how they perceive the effectiveness of TCM techniques and their service experience, and what factors affect their use. Moreover, previous studies have rarely applied theoretical frameworks to systematically explain TCM utilization behaviors, limiting the interpretability and transferability of findings across settings.</p>
<p>To address these gaps, this study aimed to (1) describe the patterns of TCM technique use and users&#x2019; perceived satisfaction and effectiveness among older adults with insomnia symptoms, and (2) explore the associations between TCM technique use and a range of factors, as conceptualized by the Andersen Behavioral Model (ABM) &#x2014;a widely applied framework for explaining healthcare utilization based on predisposing, enabling, and need factors (<xref ref-type="bibr" rid="ref31">31</xref>). Predisposing factors reflect an individual&#x2019;s tendency to use healthcare services and include demographics, social structure, and health beliefs; Enabling factors refer to resources and conditions that facilitate or hinder access, such as personal, family, and community resources; Need factors represent the immediate reasons for service use, including perceived and actual health status (<xref ref-type="bibr" rid="ref31">31</xref>). In this study, 13 potential associated factors were examined: eight predisposing factors (sex, age, marital status, education level, pre-retirement occupation, place of residence, awareness of TCM techniques, and attitude toward TCM techniques), four enabling factors (monthly personal income, type of medical insurance, availability of TCM medical institutions within 5&#x202F;km, and having relatives or friends working in TCM-related industries), and one need factor (insomnia severity).</p>
<p>By addressing these gaps, this study contributes to existing literature in several ways. First, it provides real-world evidence on utilization and user evaluation of TCM techniques for insomnia symptoms in community settings, where most older adults actually seek care. Second, by applying the ABM, this study offers a theoretically grounded framework for understanding TCM utilization behaviors, thereby facilitating interpretation of findings and enhancing their relevance to other community and primary care contexts. Third, by focusing on older adults with insomnia symptoms rather than clinically diagnosed insomnia, the study captures an often overlooked but high-risk population, offering insights that may inform the design of scalable, culturally appropriate, community-based interventions to support healthy aging.</p>
</sec>
<sec sec-type="materials|methods" id="sec2">
<label>2</label>
<title>Materials and methods</title>
<sec id="sec3">
<label>2.1</label>
<title>Study design and setting</title>
<p>We conducted a community-based cross-sectional study in 15 communities in Changsha, Hunan province, China from November 2024 to April 2025.</p>
</sec>
<sec id="sec4">
<label>2.2</label>
<title>Participants</title>
<p>Participants were eligible if they were aged 60&#x202F;years or older, had insomnia symptoms as assessed by the ISI (score &#x2265;8 indicating clinically significant insomnia symptoms) (<xref ref-type="bibr" rid="ref32 ref33 ref34 ref35">32&#x2013;35</xref>), and were able to communicate in Mandarin. Exclusion criteria were: (1) insomnia secondary to alcohol use, substance abuse or dependence, or medication side effects; (2) insomnia caused by acute environmental changes (e.g., relocation, jet lag, noise); or (3) shift workers or individuals with long-term night shift work.</p>
</sec>
<sec id="sec5">
<label>2.3</label>
<title>Sample size and sampling methods</title>
<p>The required sample size was calculated using the single-sample rate estimation formula:</p>
<disp-formula id="E1">
<mml:math id="M1">
<mml:mi>n</mml:mi>
<mml:mo>=</mml:mo>
<mml:msup>
<mml:mrow>
<mml:mo stretchy="true">(</mml:mo>
<mml:mfrac>
<mml:msub>
<mml:mi>z</mml:mi>
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2212;</mml:mo>
<mml:mfrac>
<mml:mi>&#x03B1;</mml:mi>
<mml:mn>2</mml:mn>
</mml:mfrac>
</mml:mrow>
</mml:msub>
<mml:mi>&#x03B4;</mml:mi>
</mml:mfrac>
<mml:mo stretchy="true">)</mml:mo>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:mo>&#x00B7;</mml:mo>
<mml:mi>p</mml:mi>
<mml:mo>&#x00B7;</mml:mo>
<mml:mo stretchy="true">(</mml:mo>
<mml:mn>1</mml:mn>
<mml:mo>&#x2212;</mml:mo>
<mml:mi>p</mml:mi>
<mml:mo stretchy="true">)</mml:mo>
</mml:math>
</disp-formula>
<p>Where p represents the expected prevalence of TCM technique use, <italic>&#x03B4;</italic> denotes the allowable margin of error (typically set at 3&#x2013;5%), and <italic>&#x03B1;</italic> is the probability of a Type I error, set at 0.05 (two-tailed). Based on a previous study reporting a prevalence of 17.7% among older adults aged 60&#x202F;years and above (<xref ref-type="bibr" rid="ref36">36</xref>), and with <italic>&#x03B1;</italic>&#x202F;=&#x202F;0.05 and <italic>&#x03B4;</italic>&#x202F;=&#x202F;5%, the calculated minimum sample size was 224. Allowing an anticipated non-response rate of 20%, a minimum of 280 (=224/0.8) participants was required. In addition, to ensure the stability of the binary logistic regression analysis, we assessed whether the final sample size satisfied the commonly recommended criterion of at least 10 outcome events per estimated parameter (<xref ref-type="bibr" rid="ref37">37</xref>). The available number of outcome events was sufficient to support the planned regression analyses.</p>
<p>A convenience sampling method was used to recruit the participants. To enhance the diversity of the sample, recruitment was conducted across 15 geographically dispersed communities in Changsha, encompassing both urban and rural neighborhoods. Within these communities, researchers approached potential participants at various public spaces, including community activity centers, parks, and residences, on different days of the week and times of the day.</p>
</sec>
<sec id="sec6">
<label>2.4</label>
<title>Variables and measures</title>
<p>The full version of the questionnaires used in this study is provided in <xref ref-type="supplementary-material" rid="SM1">Supplementary material</xref>.</p>
<sec id="sec7">
<label>2.4.1</label>
<title>Dependent variable</title>
<p>The dependent variable was the use of TCM techniques, assessed by the question: &#x201C;Have you ever used TCM techniques to relieve insomnia symptoms in the past 12&#x202F;months? (Yes/No).&#x201D; Participants who answered &#x201C;Yes&#x201D; were additionally asked about the type, frequency, and location of TCM technique use, as well as their satisfaction across seven domains: overall service, professionalism, cost, convenience, safety, privacy protection, and effectiveness in relieving insomnia symptoms.</p>
</sec>
<sec id="sec8">
<label>2.4.2</label>
<title>Independent variables</title>
<p>General characteristics were collected through a self-designed questionnaire: including sex, age, marital status, education level, occupation before retirement, monthly personal income, type of medical insurance, place of residence, availability of TCM medical institutions within 5&#x202F;km of the residence, and having relatives or friends engaged in TCM-related industries.</p>
<p>Awareness of TCM techniques was assessed using a six-item questionnaire developed by the research team based on literature review and expert discussion (<xref ref-type="bibr" rid="ref38 ref39 ref40">38&#x2013;40</xref>). The items covered knowledge of TCM technique types, mechanisms, procedures, safety, application for insomnia relief, and relevant policies. Each item was rated on a 4-point Likert scale (1&#x202F;=&#x202F;Completely unaware to 4&#x202F;=&#x202F;Very aware), yielding a total score ranging from 6 to 24, with higher scores indicating greater awareness. Awareness levels were categorized as low (&#x2264;25th percentile), medium (26th&#x2013;75th percentile), and high (&#x2265;76th percentile). The scale demonstrated good internal consistency in this study (Cronbach&#x2019;s <italic>&#x03B1;</italic>&#x202F;=&#x202F;0.810) and a satisfactory scale content validity index of 0.861. Attitude toward TCM techniques was assessed by one item: &#x201C;Overall, what is your attitude toward TCM techniques? (Very opposed/Not very supportive/Relatively supportive/Very supportive).&#x201D;</p>
<p>Insomnia severity was measured using the ISI (<xref ref-type="bibr" rid="ref32 ref33 ref34 ref35">32&#x2013;35</xref>), a widely used 7-item instrument assessing insomnia severity, satisfaction with sleep, functional impact, awareness of consequences, and related distress. Each item is scored on a 0&#x2013;4 scale, yielding a total score of 0&#x2013;28, with higher scores indicating more severe insomnia (0&#x2013;7: no clinical insomnia; 8&#x2013;14: mild; 15&#x2013;21: moderate; 22&#x2013;28: severe). The Chinese version of ISI has demonstrated good reliability and validity, with Cronbach&#x2019;s <italic>&#x03B1;</italic>&#x202F;=&#x202F;0.81 (<xref ref-type="bibr" rid="ref41">41</xref>).</p>
</sec>
</sec>
<sec id="sec9">
<label>2.5</label>
<title>Data collection procedures</title>
<p>Data was collected by five third-year undergraduate students who had completed the Nursing Research course, received standardized training, and had prior experience in data collection. Following ethical approval, on-site data collection was carried out at community activity centers, parks, and residences in the 15 selected communities using paper-based questionnaires.</p>
<p>Potential participants were screened for eligibility, and the study objectives and procedures were explained in detail. Written informed consent was obtained from all participants prior to recruitment. During data collection, trained interviewers provided one-on-one assistance to ensure accurate and complete responses. Upon completion, questionnaires were immediately reviewed for completeness, and any missing or unclear responses were clarified with participants on the spot. Each participant received a small gift (a pack of tissues) as a token of appreciation for their time and participation.</p>
</sec>
<sec id="sec10">
<label>2.6</label>
<title>Data analysis</title>
<p>Data analysis was conducted using IBM SPSS 25.0 (IBM Corp., Armonk, NY, USA). Participants&#x2019; characteristics and the use and satisfaction of TCM techniques were presented as frequency and percentage. Backward stepwise binary logistic regression was used to identify factors associated with the use of TCM techniques, with <italic>p</italic> &#x003E;&#x202F;0.05 as the removal criterion. &#x1D74C;2 tests were used to screen candidate influencing factors, and variables with <italic>p</italic> &#x003C;&#x202F;0.25 in &#x1D74C;2 tests were included in the regression model (<xref ref-type="bibr" rid="ref42">42</xref>). Prior to conducting binary logistic regression, we assessed multicollinearity among candidate independent variables by calculating the variance inflation factor (VIF). A VIF value exceeding 5 was considered indicative of moderate multicollinearity, and exceeding 10 indicated severe multicollinearity. In our data, all VIF values were below 5, suggesting no significant multicollinearity that would compromise the stability of the regression estimates (<xref ref-type="supplementary-material" rid="SM1">Supplementary Table S1</xref>). Statistical significance was set at 0.05 (two-sided).</p>
</sec>
</sec>
<sec sec-type="results" id="sec11">
<label>3</label>
<title>Results</title>
<sec id="sec12">
<label>3.1</label>
<title>Participants&#x2019; characteristics</title>
<p>We approached 1,167 older adults from the community, of whom 342 met the eligibility criteria. Ultimately, 311 agreed to participate and completed the survey (response rate: 90.9%).</p>
<p>Slightly more than half were female (59.2%), and 71.4% were aged 65&#x202F;years or older. About two-thirds (66.9%) were married, whereas only 10.3% had attained an education level of junior college or above. The largest occupational category before retirement was enterprise employees/workers (39.2%), followed by farmers (33.1%). Most participants (80.8%) reported a monthly personal income below 4,000 Chinese yuan, and over half (53.1%) were covered by Urban&#x2013;Rural Resident Basic Medical Insurance. A majority lived in urban areas (62.1%), nearly half (48.2%) reported access to TCM medical institutions within 5&#x202F;km of their residence, and 27.7% had relatives or friends engaged in TCM-related industries. Regarding knowledge and attitudes, 64.3% demonstrated medium to high awareness of TCM techniques, and 84.9% expressed supportive attitudes toward their use. In terms of sleep health, 87.2% reported moderate to severe insomnia (<xref ref-type="table" rid="tab1">Table 1</xref>).</p>
<table-wrap position="float" id="tab1">
<label>Table 1</label>
<caption>
<p>Participants characteristics (<italic>N</italic>&#x202F;=&#x202F;311).</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Characteristic</th>
<th align="center" valign="top"><italic>n</italic> (%)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" colspan="2">Sex</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Male</td>
<td align="char" valign="top" char="(">127 (40.8)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Female</td>
<td align="char" valign="top" char="(">184 (59.2)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Age (years)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;60&#x2013;64</td>
<td align="char" valign="top" char="(">89 (28.6)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;65&#x2013;69</td>
<td align="char" valign="top" char="(">87 (28.0)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;70&#x2013;74</td>
<td align="char" valign="top" char="(">73 (23.5)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;&#x2265;75</td>
<td align="char" valign="top" char="(">62 (19.9)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Marital status</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Married</td>
<td align="char" valign="top" char="(">208 (66.9)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Unmarried/Divorced/Widowed</td>
<td align="char" valign="top" char="(">103 (33.1)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Education level</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Primary school or below</td>
<td align="char" valign="top" char="(">123 (39.5)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Junior high school</td>
<td align="char" valign="top" char="(">84 (27.0)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;High school/Technical secondary/Vocational school</td>
<td align="char" valign="top" char="(">72 (23.2)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Junior college or above</td>
<td align="char" valign="top" char="(">32 (10.3)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Occupation before retirement</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Civil servants/Public institution staff</td>
<td align="char" valign="top" char="(">61 (19.6)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Enterprise employees/Workers</td>
<td align="char" valign="top" char="(">122 (39.2)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Self-employed</td>
<td align="char" valign="top" char="(">25 (8.0)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Farmers</td>
<td align="char" valign="top" char="(">103 (33.1)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Monthly personal income (Chinese yuan)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;&#x003C;2000</td>
<td align="char" valign="top" char="(">110 (35.4)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;2000&#x2013;2,999</td>
<td align="char" valign="top" char="(">72 (23.2)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;3,000&#x2013;3,999</td>
<td align="char" valign="top" char="(">69 (22.2)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;&#x2265;4,000</td>
<td align="char" valign="top" char="(">60 (19.3)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Type of medical insurance</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Urban Employee Basic Medical Insurance</td>
<td align="char" valign="top" char="(">130 (41.8)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Urban&#x2013;Rural Resident Basic Medical Insurance</td>
<td align="char" valign="top" char="(">165 (53.1)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;No insurance</td>
<td align="char" valign="top" char="(">16 (5.1)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Place of residence</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Urban areas</td>
<td align="char" valign="top" char="(">193 (62.1)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Rural areas</td>
<td align="char" valign="top" char="(">118 (37.9)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Presence of TCM medical institutions within 5&#x202F;km of the residence<sup>&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Yes</td>
<td align="char" valign="top" char="(">150 (48.2)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;No</td>
<td align="char" valign="top" char="(">96 (30.9)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Not sure</td>
<td align="char" valign="top" char="(">65 (20.9)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Relatives/friends working in TCM-related industries</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Yes</td>
<td align="char" valign="top" char="(">86 (27.7)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;No</td>
<td align="char" valign="top" char="(">225 (72.3)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Awareness of TCM techniques</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Low</td>
<td align="char" valign="top" char="(">111 (35.7)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Medium</td>
<td align="char" valign="top" char="(">135 (43.4)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;High</td>
<td align="char" valign="top" char="(">65 (20.9)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Attitude toward TCM techniques</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very opposed / Not very supportive</td>
<td align="char" valign="top" char="(">47 (15.1)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Relatively supportive/Very supportive</td>
<td align="char" valign="top" char="(">264 (84.9)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Insomnia severity</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Mild</td>
<td align="char" valign="top" char="(">40 (12.9)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Moderate</td>
<td align="char" valign="top" char="(">171 (55.0)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Severe</td>
<td align="char" valign="top" char="(">100 (32.2)</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>TCM, Traditional Chinese Medicine.</p>
<p><sup>&#x002A;</sup>Includes TCM hospitals, TCM departments of general hospitals, and integrated traditional Chinese and Western medicine hospitals.</p>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="sec13">
<label>3.2</label>
<title>Use and evaluation of TCM techniques</title>
<p>Among 311 participants, 51.1% reported using TCM techniques for insomnia. The most commonly used approaches were tuina (71.1%), moxibustion (69.8%), needle embedding (59.1%), and acupuncture (58.5%), followed by auricular acupressure (39.6%). Regarding utilization frequency, 34.6% used the techniques occasionally and 29.6% used them 1&#x2013;2 times per month. Most participants sought services at TCM hospitals (72.3%), private clinics (50.3%), or general hospital TCM departments (47.2%), while around one-third reported accessing services at wellness centers, community health service centers, or at home. Regarding satisfaction (overall service, professionalism, cost, convenience, safety, privacy protection, and insomnia relief effectiveness), 69.8&#x2013;81.8% of participants expressed satisfaction. However, only 20.1&#x2013;28.3% rated themselves as &#x201C;very satisfied&#x201D; across these dimensions, indicating that high overall satisfaction coexisted with relatively low proportions of high-level satisfaction (<xref ref-type="table" rid="tab2">Table 2</xref>).</p>
<table-wrap position="float" id="tab2">
<label>Table 2</label>
<caption>
<p>Use and satisfaction of TCM techniques among older adults with insomnia (<italic>N</italic>&#x202F;=&#x202F;311).</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Variables</th>
<th align="center" valign="top"><italic>n</italic> (%)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" colspan="2">Use experience</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;No</td>
<td align="char" valign="top" char="(">152 (48.9)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Yes</td>
<td align="char" valign="top" char="(">159 (51.1)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Type of techniques used<sup>&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Tuina (therapeutic massage)</td>
<td align="char" valign="top" char="(">113 (71.1)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Moxibustion</td>
<td align="char" valign="top" char="(">111 (69.8)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Needle embedding</td>
<td align="char" valign="top" char="(">94 (59.1)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Acupuncture</td>
<td align="char" valign="top" char="(">93 (58.5)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Auricular acupressure (ear seeds)</td>
<td align="char" valign="top" char="(">63 (39.6)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Others</td>
<td align="char" valign="top" char="(">60 (37.8)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Frequency of use<sup>#</sup></td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Daily</td>
<td align="char" valign="top" char="(">20 (12.6)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;1&#x2013;2 times per week</td>
<td align="char" valign="top" char="(">37 (23.3)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;1&#x2013;2 times per month</td>
<td align="char" valign="top" char="(">47 (29.6)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Occasionally (&#x2264;10 times/year)</td>
<td align="char" valign="top" char="(">55 (34.6)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Places of service<sup>&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;TCM hospital</td>
<td align="char" valign="top" char="(">115 (72.3)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Private TCM clinic</td>
<td align="char" valign="top" char="(">80 (50.3)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;TCM department of general hospital</td>
<td align="char" valign="top" char="(">75 (47.2)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Wellness center</td>
<td align="char" valign="top" char="(">63 (39.6)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Community health service center</td>
<td align="char" valign="top" char="(">62 (39.0)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;At home</td>
<td align="char" valign="top" char="(">55 (34.6)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Overall satisfaction with services<sup>#</sup></td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very satisfied</td>
<td align="char" valign="top" char="(">32 (20.1)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Satisfied</td>
<td align="char" valign="top" char="(">87 (54.7)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Dissatisfied</td>
<td align="char" valign="top" char="(">30 (18.9)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very dissatisfied</td>
<td align="char" valign="top" char="(">10 (6.3)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Professionalism rating<sup>#</sup></td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very satisfied</td>
<td align="char" valign="top" char="(">45 (28.3)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Satisfied</td>
<td align="char" valign="top" char="(">76 (47.8)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Dissatisfied</td>
<td align="char" valign="top" char="(">27 (17.0)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very dissatisfied</td>
<td align="char" valign="top" char="(">11 (6.9)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Cost satisfaction<sup>#</sup></td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very satisfied</td>
<td align="char" valign="top" char="(">35 (22.0)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Satisfied</td>
<td align="char" valign="top" char="(">76 (47.8)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Dissatisfied</td>
<td align="char" valign="top" char="(">30 (18.9)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very dissatisfied</td>
<td align="char" valign="top" char="(">18 (11.3)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Convenience rating<sup>#</sup></td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very satisfied</td>
<td align="char" valign="top" char="(">38 (23.9)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Satisfied</td>
<td align="char" valign="top" char="(">76 (47.8)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Dissatisfied</td>
<td align="char" valign="top" char="(">35 (22.0)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very dissatisfied</td>
<td align="char" valign="top" char="(">10 (6.3)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Safety rating</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very satisfied</td>
<td align="char" valign="top" char="(">40 (25.2)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Satisfied</td>
<td align="char" valign="top" char="(">90 (56.6)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Dissatisfied</td>
<td align="char" valign="top" char="(">20 (12.6)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very dissatisfied</td>
<td align="char" valign="top" char="(">9 (5.7)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Privacy protection satisfaction<sup>#</sup></td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very satisfied</td>
<td align="char" valign="top" char="(">40 (25.2)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Satisfied</td>
<td align="char" valign="top" char="(">86 (54.1)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Dissatisfied</td>
<td align="char" valign="top" char="(">22 (13.8)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very dissatisfied</td>
<td align="char" valign="top" char="(">11 (6.9)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Perceived relief of insomnia symptoms<sup>#</sup></td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very satisfied</td>
<td align="char" valign="top" char="(">36 (22.6)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Satisfied</td>
<td align="char" valign="top" char="(">88 (55.3)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Dissatisfied</td>
<td align="char" valign="top" char="(">22 (13.8)</td>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Very dissatisfied</td>
<td align="char" valign="top" char="(">13 (8.2)</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>TCM, Traditional Chinese Medicine.</p>
<p><sup>&#x002A;</sup>Multiple responses; percentages are based on actual users (<italic>n</italic>&#x202F;=&#x202F;159), and totals can exceed 100%.</p>
<p><sup>#</sup>Percentages are based on actual users (<italic>n</italic>&#x202F;=&#x202F;159).</p>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="sec14">
<label>3.3</label>
<title>Associated factors of TCM technique use</title>
<p>Candidate variables identified in univariate analyses (<xref ref-type="table" rid="tab3">Table 3</xref>, <italic>p</italic> &#x003C;&#x202F;0.25) were entered into a backward stepwise logistic regression model. Four independent associated factors of TCM technique use were identified (<xref ref-type="table" rid="tab4">Table 4</xref>). Three variables entered into the initial model-education level, type of medical insurance, and place of residence-were not retained in the final model due to lack of independent statistical significance (see <xref ref-type="supplementary-material" rid="SM1">Supplementary Table S2</xref> for details).</p>
<table-wrap position="float" id="tab3">
<label>Table 3</label>
<caption>
<p>Univariate analysis of factors associated with the use of TCM techniques (<italic>N</italic>&#x202F;=&#x202F;311).</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top" rowspan="3">Factors</th>
<th align="center" valign="top" colspan="2">TCM techniques use</th>
<th align="center" valign="top" rowspan="3">
<italic>&#x03C7;<sup>2</sup></italic>
</th>
<th align="center" valign="top" rowspan="3">
<italic>p</italic>
</th>
</tr>
<tr>
<th align="center" valign="top">No</th>
<th align="center" valign="top">Yes</th>
</tr>
<tr>
<th align="center" valign="top"><italic>n</italic> (%)</th>
<th align="center" valign="top"><italic>n</italic> (%)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="middle">Sex</td>
<td/>
<td/>
<td align="char" valign="middle" char=".">0.061</td>
<td align="char" valign="middle" char=".">0.805</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Male</td>
<td align="char" valign="middle" char="(">61 (48.0)</td>
<td align="char" valign="middle" char="(">66 (52.0)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Female</td>
<td align="char" valign="middle" char="(">91 (49.5)</td>
<td align="char" valign="middle" char="(">93 (50.5)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">Age (years)</td>
<td/>
<td/>
<td align="char" valign="middle" char=".">3.778</td>
<td align="char" valign="middle" char=".">0.286</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;60&#x2013;64</td>
<td align="char" valign="middle" char="(">45 (50.6)</td>
<td align="char" valign="middle" char="(">44 (49.4)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;65&#x2013;69</td>
<td align="char" valign="middle" char="(">35 (40.2)</td>
<td align="char" valign="middle" char="(">52 (59.8)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;70&#x2013;74</td>
<td align="char" valign="middle" char="(">39 (53.4)</td>
<td align="char" valign="middle" char="(">34 (46.6)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;&#x2265;75</td>
<td align="char" valign="middle" char="(">33 (53.2)</td>
<td align="char" valign="middle" char="(">29 (46.8)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">Marital status</td>
<td/>
<td/>
<td align="char" valign="middle" char=".">0.104</td>
<td align="char" valign="middle" char=".">0.747</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Married</td>
<td align="char" valign="middle" char="(">103 (49.5)</td>
<td align="char" valign="middle" char="(">105 (50.5)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Unmarried/Divorced/Widowed</td>
<td align="char" valign="middle" char="(">49 (47.6)</td>
<td align="char" valign="middle" char="(">54 (52.4)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x002A;Education level</td>
<td/>
<td/>
<td align="char" valign="middle" char=".">10.085</td>
<td align="char" valign="middle" char=".">0.018</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Primary school or below</td>
<td align="char" valign="middle" char="(">65 (52.8)</td>
<td align="char" valign="middle" char="(">58 (47.2)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Junior high school</td>
<td align="char" valign="middle" char="(">48 (57.1)</td>
<td align="char" valign="middle" char="(">36 (42.9)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;High school/Technical secondary/Vocational school</td>
<td align="char" valign="middle" char="(">30 (41.7)</td>
<td align="char" valign="middle" char="(">42 (58.3)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Junior college or above</td>
<td align="char" valign="middle" char="(">9 (28.1)</td>
<td align="char" valign="middle" char="(">23 (71.9)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x002A;Occupation before retirement</td>
<td/>
<td/>
<td align="char" valign="middle" char=".">25.359</td>
<td align="char" valign="middle" char=".">&#x003C;0.001</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Civil servants/Public institution staff</td>
<td align="char" valign="middle" char="(">25 (41.0)</td>
<td align="char" valign="middle" char="(">36 (59.0)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Enterprise employees/Workers</td>
<td align="char" valign="middle" char="(">45 (36.9)</td>
<td align="char" valign="middle" char="(">77 (63.1)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Self-employed</td>
<td align="char" valign="middle" char="(">11 (44.0)</td>
<td align="char" valign="middle" char="(">14 (56.0)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Farmers</td>
<td align="char" valign="middle" char="(">71 (68.9)</td>
<td align="char" valign="middle" char="(">32 (31.1)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">Monthly personal income (Chinese yuan)</td>
<td/>
<td/>
<td align="char" valign="middle" char=".">3.300</td>
<td align="char" valign="middle" char=".">0.348</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;&#x003C;2000</td>
<td align="char" valign="middle" char="(">57 (51.8)</td>
<td align="char" valign="middle" char="(">53 (48.2)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;2000&#x2013;2,999</td>
<td align="char" valign="middle" char="(">30 (41.7)</td>
<td align="char" valign="middle" char="(">42 (58.3)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;3,000&#x2013;3,999</td>
<td align="char" valign="middle" char="(">38 (55.1)</td>
<td align="char" valign="middle" char="(">31 (44.9)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;&#x2265;4,000</td>
<td align="char" valign="middle" char="(">27 (45.0)</td>
<td align="char" valign="middle" char="(">33 (55.0)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x002A;Type of medical insurance</td>
<td/>
<td/>
<td align="char" valign="middle" char=".">6.028</td>
<td align="char" valign="middle" char=".">0.049</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Urban Employee Basic Medical Insurance</td>
<td align="char" valign="middle" char="(">53 (40.8)</td>
<td align="char" valign="middle" char="(">77 (59.2)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Urban&#x2013;Rural Resident Basic Medical Insurance</td>
<td align="char" valign="middle" char="(">91 (55.2)</td>
<td align="char" valign="middle" char="(">74 (44.8)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;No insurance</td>
<td align="char" valign="middle" char="(">8 (50.0)</td>
<td align="char" valign="middle" char="(">8 (50.0)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x002A;Place of residence</td>
<td/>
<td/>
<td align="char" valign="middle" char=".">8.306</td>
<td align="char" valign="middle" char=".">0.004</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Urban areas</td>
<td align="char" valign="middle" char="(">82 (42.5)</td>
<td align="char" valign="middle" char="(">111 (57.5)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Rural areas</td>
<td align="char" valign="middle" char="(">70 (59.3)</td>
<td align="char" valign="middle" char="(">48 (40.7)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">Presence of TCM medical institutions within 5&#x202F;km of the residence<sup>#</sup></td>
<td/>
<td/>
<td align="char" valign="middle" char=".">0.648</td>
<td align="char" valign="middle" char=".">0.723</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Yes</td>
<td align="char" valign="middle" char="(">70 (46.7)</td>
<td align="char" valign="middle" char="(">80 (53.3)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;No</td>
<td align="char" valign="middle" char="(">48 (50.0)</td>
<td align="char" valign="middle" char="(">48 (50.0)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Not sure</td>
<td align="char" valign="middle" char="(">34 (52.3)</td>
<td align="char" valign="middle" char="(">31 (47.7)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x002A;Relatives/friends working in TCM-related industries</td>
<td/>
<td/>
<td align="char" valign="middle" char=".">7.829</td>
<td align="char" valign="middle" char=".">0.005</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Yes</td>
<td align="char" valign="middle" char="(">31 (36.0)</td>
<td align="char" valign="middle" char="(">55 (64.0)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;No</td>
<td align="char" valign="middle" char="(">121 (53.8)</td>
<td align="char" valign="middle" char="(">104 (46.2)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x002A;Awareness of TCM techniques</td>
<td/>
<td/>
<td align="char" valign="middle" char=".">81.893</td>
<td align="char" valign="middle" char=".">&#x003C;0.001</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Low</td>
<td align="char" valign="middle" char="(">89 (80.2)</td>
<td align="char" valign="middle" char="(">22 (19.8)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Medium</td>
<td align="char" valign="middle" char="(">55 (40.7)</td>
<td align="char" valign="middle" char="(">80 (59.3)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;High</td>
<td align="char" valign="middle" char="(">8 (12.3)</td>
<td align="char" valign="middle" char="(">57 (87.7)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">Attitude toward TCM techniques</td>
<td/>
<td/>
<td align="char" valign="middle" char=".">0.095</td>
<td align="char" valign="middle" char=".">0.758</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Very opposed/Not very supportive</td>
<td align="char" valign="middle" char="(">22 (46.8)</td>
<td align="char" valign="middle" char="(">25 (53.2)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Relatively supportive/Very supportive</td>
<td align="char" valign="middle" char="(">130 (49.2)</td>
<td align="char" valign="middle" char="(">134 (50.8)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x002A;Insomnia severity</td>
<td/>
<td/>
<td align="char" valign="middle" char=".">28.813</td>
<td align="char" valign="middle" char=".">&#x003C;0.001</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Mild</td>
<td align="char" valign="middle" char="(">30 (75.0)</td>
<td align="char" valign="middle" char="(">10 (25.0)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Moderate</td>
<td align="char" valign="middle" char="(">93 (54.4)</td>
<td align="char" valign="middle" char="(">78 (45.6)</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="top">&#x2003;Severe</td>
<td align="char" valign="top" char="(">29 (29.0)</td>
<td align="char" valign="top" char="(">71 (71.0)</td>
<td/>
<td/>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>TCM, Traditional Chinese Medicine.</p>
<p><sup>&#x002A;</sup>Candidate-independent variable for multivariate analysis (<italic>p</italic>&#x202F;&#x003C;&#x202F;0.25).</p>
<p><sup>#</sup>Includes TCM hospitals, TCM departments of general hospitals, and integrated traditional Chinese and Western medicine hospitals.</p>
</table-wrap-foot>
</table-wrap>
<table-wrap position="float" id="tab4">
<label>Table 4</label>
<caption>
<p>Backward stepwise binary logistic regression of factors associated with the use of TCM techniques (<italic>N</italic>&#x202F;=&#x202F;311).</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top" rowspan="2">Variables</th>
<th align="center" valign="top" rowspan="2">B</th>
<th align="center" valign="top" rowspan="2">SE.</th>
<th align="center" valign="top" rowspan="2">
<italic>p</italic>
</th>
<th align="center" valign="top" rowspan="2">Exp (B)</th>
<th align="center" valign="top" colspan="2">95% CI for EXP (B)</th>
</tr>
<tr>
<th align="center" valign="top">Lower</th>
<th align="center" valign="top">Upper</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="middle" colspan="7">Predisposing factor</td>
</tr>
<tr>
<td align="left" valign="middle" colspan="7">Occupation before retirement</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Farmers</td>
<td align="center" valign="middle">Reference</td>
<td/>
<td/>
<td/>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Civil servants/Public institution staff</td>
<td align="center" valign="top">0.673</td>
<td align="char" valign="top" char=".">0.413</td>
<td align="char" valign="top" char=".">0.103</td>
<td align="char" valign="top" char=".">1.960</td>
<td align="char" valign="top" char=".">0.873</td>
<td align="char" valign="top" char=".">4.401</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Enterprise employees/Workers</td>
<td align="center" valign="top">1.346</td>
<td align="char" valign="top" char=".">0.347</td>
<td align="char" valign="top" char=".">&#x003C;0.001</td>
<td align="char" valign="top" char=".">3.843</td>
<td align="char" valign="top" char=".">1.948</td>
<td align="char" valign="top" char=".">7.580</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Self-employed</td>
<td align="center" valign="top">0.488</td>
<td align="char" valign="top" char=".">0.552</td>
<td align="char" valign="top" char=".">0.377</td>
<td align="char" valign="top" char=".">1.629</td>
<td align="char" valign="top" char=".">0.552</td>
<td align="char" valign="top" char=".">4.810</td>
</tr>
<tr>
<td align="left" valign="middle" colspan="7">Awareness of TCM techniques</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Low</td>
<td align="center" valign="middle">Reference</td>
<td/>
<td/>
<td/>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Medium</td>
<td align="center" valign="top">1.623</td>
<td align="char" valign="top" char=".">0.317</td>
<td align="char" valign="middle" char=".">&#x003C;0.001</td>
<td align="char" valign="top" char=".">5.069</td>
<td align="char" valign="top" char=".">2.723</td>
<td align="char" valign="top" char=".">9.434</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;High</td>
<td align="center" valign="top">3.229</td>
<td align="char" valign="top" char=".">0.480</td>
<td align="char" valign="middle" char=".">&#x003C;0.001</td>
<td align="char" valign="top" char=".">25.255</td>
<td align="char" valign="top" char=".">9.864</td>
<td align="char" valign="top" char=".">64.660</td>
</tr>
<tr>
<td align="left" valign="middle" colspan="7">Enabling factor</td>
</tr>
<tr>
<td align="left" valign="middle" colspan="7">Relatives/friends working in TCM-related industries</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;No</td>
<td align="center" valign="middle">Reference</td>
<td/>
<td/>
<td/>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Yes</td>
<td align="center" valign="top">0.847</td>
<td align="char" valign="top" char=".">0.327</td>
<td align="char" valign="top" char=".">0.010</td>
<td align="char" valign="top" char=".">2.332</td>
<td align="char" valign="top" char=".">1.228</td>
<td align="char" valign="top" char=".">4.428</td>
</tr>
<tr>
<td align="left" valign="middle" colspan="7">Need factor</td>
</tr>
<tr>
<td align="left" valign="middle" colspan="7">Insomnia severity</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Mild</td>
<td align="center" valign="middle">Reference</td>
<td/>
<td/>
<td/>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Moderate</td>
<td align="center" valign="top">1.309</td>
<td align="char" valign="top" char=".">0.498</td>
<td align="char" valign="top" char=".">0.009</td>
<td align="char" valign="top" char=".">3.702</td>
<td align="char" valign="top" char=".">1.395</td>
<td align="char" valign="top" char=".">9.825</td>
</tr>
<tr>
<td align="left" valign="middle">&#x2003;Severe</td>
<td align="center" valign="top">1.977</td>
<td align="char" valign="top" char=".">0.524</td>
<td align="char" valign="top" char=".">&#x003C;0.001</td>
<td align="char" valign="top" char=".">7.224</td>
<td align="char" valign="top" char=".">2.586</td>
<td align="char" valign="top" char=".">20.178</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>TCM, Traditional Chinese Medicine; B, unstandardized regression coefficient; SE, standard error; Exp(B), odds ratio; CI, confidence interval.</p>
<p>Model summary: Cox &#x0026; Snell R<sup>2</sup>&#x202F;=&#x202F;0.336; Nagelkerke R<sup>2</sup>&#x202F;=&#x202F;0.448; Omnibus test: Chi-square&#x202F;=&#x202F;127.210, <italic>p</italic>&#x202F;&#x003C;&#x202F;0.001; Hosmer&#x2013;Lemeshow test: Chi-square&#x202F;=&#x202F;10.306, <italic>p</italic>&#x202F;=&#x202F;0.172.</p>
</table-wrap-foot>
</table-wrap>
<p>Among predisposing factors, occupation before retirement and TCM techniques awareness were significant. Compared with farmers, enterprise employees/workers showed higher odds of use (odds ratio [OR]&#x202F;=&#x202F;3.84, 95% confidence interval [CI]: 1.95&#x2013;7.58, <italic>p</italic>&#x202F;&#x003C;&#x202F;0.001). Those with medium awareness had fivefold higher odds (OR&#x202F;=&#x202F;5.07, 95% CI: 2.72&#x2013;9.43, <italic>p</italic>&#x202F;&#x003C;&#x202F;0.001), and those with high awareness had 25 times higher odds (OR&#x202F;=&#x202F;25.26, 95% CI: 9.86&#x2013;64.66, <italic>p</italic>&#x202F;&#x003C;&#x202F;0.001), compared with those with low awareness.</p>
<p>One enabling factor and one need factor were significant. Participants with relatives or friends engaged in TCM-related industries had greater odds of use compared with those without (OR&#x202F;=&#x202F;2.33, 95% CI: 1.23&#x2013;4.43, <italic>p</italic>&#x202F;=&#x202F;0.01). Participants with moderate (OR&#x202F;=&#x202F;3.70, 95% CI: 1.40&#x2013;9.83, <italic>p</italic>&#x202F;=&#x202F;0.009) and severe insomnia (OR&#x202F;=&#x202F;7.22, 95% CI: 2.59&#x2013;20.18, <italic>p</italic>&#x202F;&#x003C;&#x202F;0.001) were more likely to use TCM techniques than those with mild symptoms.</p>
</sec>
</sec>
<sec sec-type="discussion" id="sec15">
<label>4</label>
<title>Discussion</title>
<p>This exploratory study provides initial real-world evidence on the use of TCM techniques for managing insomnia symptoms among community-dwelling older adults in China. We found that 51.1% of participants reported using at least one TCM technique, with tuina, moxibustion, needle embedding, and acupuncture being the most frequently used methods. Overall satisfaction with TCM services was generally high across domains such as safety and professionalism, yet fewer participants reported being &#x201C;very satisfied.&#x201D; Four associated factors of TCM use were identified based on the ABM: pre-retirement occupation and awareness of TCM techniques (predisposing); having relatives or friends working in TCM-related industries (enabling), and insomnia severity (need).</p>
<p>The prevalence of TCM technique use among older adults with insomnia symptoms in this study (51.1%) was substantially higher than the 17.7% reported in a previous study on TCM preventive service use among older adults (<xref ref-type="bibr" rid="ref36">36</xref>). This discrepancy may be primarily attributed to differences in health needs: prior research focused on preventive care among individuals without acute health concerns, whereas our study targeted those with existing insomnia symptoms, likely increasing perceived need and motivation for service utilization. Additionally, participants were recruited from community activity centers, parks, or residences, which may underrepresent individuals who are less socially active or have more severe mobility limitations. Therefore, the observed usage rate of 51.1% should be interpreted with caution and needs verification in future studies employing probability sampling designs. When compared with the reported clinical uptake of CBT-I (1&#x2013;29%) (<xref ref-type="bibr" rid="ref19">19</xref>), TCM techniques use was significantly higher, underscoring their cultural acceptability and potential as community-based strategies for managing insomnia symptoms.</p>
<p>Regarding specific techniques, tuina (71.1%) and moxibustion (69.8%) were most frequently used, followed by needle embedding (59.1%) and acupuncture (58.5%), while auricular acupressure had the lowest uptake (39.6%). Notably, despite strong evidence supporting acupuncture and auricular acupressure for insomnia symptoms (<xref ref-type="bibr" rid="ref27">27</xref>, <xref ref-type="bibr" rid="ref29">29</xref>), their real-world utilization was relatively low. Possible reasons include the minimally invasive nature of acupuncture, which may cause pain or fear of adverse events, and practical limitations of auricular acupressure such as discomfort, adhesive instability, and unfamiliarity among older adults. These findings highlight the gap between evidence and real-world implementation and suggest the need for strategies such as simplified application protocols, enhanced user education, and material improvements to enhance uptake.</p>
<p>Despite relatively high uptake, only 20.1% of participants reported being &#x201C;very satisfied,&#x201D; and just 22.6% perceived the interventions as highly effective in relieving insomnia symptoms. This pattern suggests that while TCM techniques were generally acceptable and positively received in community settings, their perceived benefits or service experience rarely reached a level of strong positive evaluation among most users. Such attenuation in satisfaction intensity may reflect real-world implementation factors. Although TCM techniques are increasingly guided by evidence-based principles (<xref ref-type="bibr" rid="ref43">43</xref>), variability in practitioner training, treatment fidelity, and service delivery settings may limit the consistency of therapeutic effects. In this study, services were delivered across heterogeneous settings, including private clinics, wellness centers, community health service centers, and home-based care. Moreover, more than 60% of participants reported only occasional use or use once or twice per month, which may be insufficient to achieve optimal or sustained symptom improvement. Given the cross-sectional design, it is not possible to determine whether the relatively low proportion of &#x201C;very satisfied&#x201D; responses primarily reflects limitations in implementation quality or misalignment between user expectations and achievable treatment effects. Nevertheless, these findings underscore the importance of strengthening implementation quality and patient education to enhance both satisfaction intensity and perceived effectiveness of community-based TCM services.</p>
<p>Predisposing factors such as occupation and awareness significantly influenced TCM technique utilization. Participants who were former enterprise employees or workers were more likely than farmers to use TCM techniques, possibly reflecting socioeconomic differences, higher health literacy, and greater exposure to health information. In contrast, farmers may be more likely to perceive insomnia symptoms as a &#x201C;normal&#x201D; part of aging and therefore pay less attention to seeking treatment, supported by evidence showing lower sleep-related healthcare utilization in rural adults (any insomnia symptoms: adjusted OR&#x202F;=&#x202F;0.45, <italic>p</italic>&#x202F;&#x003C;&#x202F;0.001; insomnia disorder: adjusted OR&#x202F;=&#x202F;0.41, <italic>p</italic>&#x202F;&#x003C;&#x202F;0.001) (<xref ref-type="bibr" rid="ref24">24</xref>). Awareness of TCM techniques emerged as the strongest determinant, consistent with previous findings (<xref ref-type="bibr" rid="ref36">36</xref>), underscoring the critical role of health education and targeted outreach in improving uptake, particularly in populations with low awareness.</p>
<p>Among enabling factors, having relatives or friends engaged in TCM-related industries may facilitate utilization by providing social support or enhancing TCM health literacy (<xref ref-type="bibr" rid="ref38">38</xref>), thereby increasing awareness and perceived accessibility of TCM techniques. However, our study did not empirically test these pathways, underscoring the need for future research to clarify the deeper mechanisms. These results highlight the potential of TCM universities to strengthen community engagement and expand outreach programs, which may serve as effective strategies to increase access and reduce disparities in TCM utilization. In addition, community-level interventions, such as integrating TCM services into primary care and leveraging social networks, could further enhance equitable access.</p>
<p>The need factor, insomnia severity, positively predicted TCM use, indicating that perceived or actual health need remains a powerful motivator for seeking care. This aligns with Andersen&#x2019;s proposition that need factors are the most immediate cause of health service utilization (<xref ref-type="bibr" rid="ref31">31</xref>) and is consistent with prior evidence showing that symptom burden drives demand for complementary therapies in older adults (<xref ref-type="bibr" rid="ref24">24</xref>, <xref ref-type="bibr" rid="ref36">36</xref>).</p>
<p>Although the observed associations between TCM awareness, insomnia severity, and TCM utilization may appear conceptually intuitive, empirically demonstrating these relationships in community-dwelling older adults remains important. Such evidence supports the applicability of the ABM in the context of TCM use for insomnia and provides a theory-informed basis for designing targeted community interventions. Quantifying these associations also helps identify modifiable targets, such as awareness and perceived need, that can be addressed through health education and service delivery strategies.</p>
<sec id="sec16">
<label>4.1</label>
<title>Implications for clinical practice, policy, and research</title>
<p>Collectively, these findings provide exploratory insights that may guide future research and inform the development of culturally appropriate interventions within similar contexts.</p>
<p>Clinically, strengthening health education on insomnia and TCM techniques may help improve appropriate uptake and adherence, particularly among older adults with limited awareness. Educational efforts should emphasize realistic expectations, recommended treatment frequency, and potential benefits and limitations of different TCM techniques. In addition, simplifying application protocols and improving materials for techniques such as auricular acupressure may enhance acceptability and sustained use in community settings.</p>
<p>At the policy level, integrating selected TCM services into primary care and community health centers may improve accessibility and continuity of care for older adults with insomnia symptoms. Such integration could help standardize service delivery and reduce variability across practice settings. Importantly, local TCM universities may play a key role in supporting community-based implementation through practitioner training, continuing education, and outreach programs. By leveraging academic expertise and institutional resources, TCM universities could help strengthen practitioner competency, promote evidence-informed practice, and enhance the overall quality and credibility of community TCM services.</p>
<p>Future research should move beyond utilization patterns to examine implementation quality, treatment fidelity, and optimal treatment frequency in real-world settings. Longitudinal and interventional studies are needed to clarify causal relationships between TCM use and insomnia outcomes and to assess whether improvements in practitioner training and service standardization translate into higher satisfaction intensity and perceived effectiveness among older adults.</p>
</sec>
<sec id="sec17">
<label>4.2</label>
<title>Limitations and future research</title>
<p>This study has several limitations. First, its cross-sectional design cannot establish causal inferences. Future longitudinal or interventional studies are needed to validate these causal relationships and assess the real-world effectiveness of TCM techniques. Second, TCM use, satisfaction, and perceived effectiveness were self-reported and may be affected by recall and social desirability biases. Although TCM use was assessed specifically for insomnia relief, concurrent use for other coexisting health conditions common in older adults could not be fully distinguished, which may have influenced satisfaction and perceived effectiveness. Future studies may benefit from incorporating more detailed, indication-specific assessments of TCM use to better isolate insomnia-related effects. Third, we did not assess participants&#x2019; chronic disease comorbidities and psychological symptoms. The absence of these variables may have led to residual confounding, influencing both insomnia symptoms and treatment-seeking behaviors. Future studies should incorporate comprehensive health and psychological assessments to better account for these potential confounders. In addition, the relatively broad categorization of pre-retirement occupation and place of residence may have limited the ability to capture more nuanced socioeconomic and environmental differences related to TCM utilization. Future studies with larger samples may employ more granular classifications to better capture heterogeneity in TCM use. Finally, participants were recruited from 15 communities in a single city using convenience sampling, which may have resulted in the underrepresentation of frail, homebound, or socially less active older adults and, consequently, may limit the generalizability of the findings. Future research should consider probability-based sampling strategies and multisite designs to improve representativeness and strengthen external validity.</p>
</sec>
</sec>
<sec sec-type="conclusions" id="sec18">
<label>5</label>
<title>Conclusion</title>
<p>This exploratory study provides preliminary evidence on the real-world use of TCM techniques for insomnia symptoms among older adults in China. More than half of participants reported using at least one TCM technique, yet only a minority rated the TCM services as &#x201C;very satisfied&#x201D; or &#x201C;highly effective,&#x201D; suggesting a gap between utilization and expected outcomes. Four associated factors of TCM use were identified under the ABM: pre-retirement occupation and awareness of TCM techniques (predisposing), having relatives or friends working in TCM-related industries (enabling), and insomnia severity (need). These findings may inform the design of culturally sensitive interventions to manage insomnia symptoms among community-dwelling older adults in similar contexts. Future research should continue to assess real-world implementation quality, determinants of perceived effectiveness, and strategies to improve both utilization and user satisfaction.</p>
</sec>
</body>
<back>
<sec sec-type="data-availability" id="sec19">
<title>Data availability statement</title>
<p>The raw data supporting the conclusions of this article will be available from the corresponding author upon reasonable request.</p>
</sec>
<sec sec-type="ethics-statement" id="sec20">
<title>Ethics statement</title>
<p>The studies involving humans were approved by the Hunan University of Chinese Medicine Nursing and Behavioral Medicine Science and Technology Ethics Review Committee (Approval No: ZYYHLLL-2024-03-005). The studies were conducted in accordance with the local legislation and institutional requirements. The participants provided their written informed consent to participate in this study.</p>
</sec>
<sec sec-type="author-contributions" id="sec21">
<title>Author contributions</title>
<p>YM: Investigation, Data curation, Project administration, Writing &#x2013; original draft, Funding acquisition. LH: Conceptualization, Validation, Methodology, Writing &#x2013; review &#x0026; editing. XS: Writing &#x2013; review &#x0026; editing, Formal analysis. YZ: Writing &#x2013; review &#x0026; editing, Formal analysis. SL: Investigation, Writing &#x2013; review &#x0026; editing. JP: Writing &#x2013; review &#x0026; editing, Investigation. YL: Investigation, Writing &#x2013; review &#x0026; editing. XW: Writing &#x2013; review &#x0026; editing, Investigation. BX: Supervision, Methodology, Resources, Writing &#x2013; review &#x0026; editing, Conceptualization, Funding acquisition.</p>
</sec>
<ack>
<title>Acknowledgments</title>
<p>We sincerely thank all the older adults who participated in this study for their time, effort, and valuable contributions.</p>
</ack>
<sec sec-type="COI-statement" id="sec22">
<title>Conflict of interest</title>
<p>The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="ai-statement" id="sec23">
<title>Generative AI statement</title>
<p>The author(s) declared that Generative AI was used in the creation of this manuscript. During the preparation of this work the author used DeepSeek to improve the readability and language of the manuscript. After using this tool, the author reviewed and edited the content as needed and takes full responsibility for the content of the published article.</p>
<p>Any alternative text (alt text) provided alongside figures in this article has been generated by Frontiers with the support of artificial intelligence and reasonable efforts have been made to ensure accuracy, including review by the authors wherever possible. If you identify any issues, please contact us.</p>
</sec>
<sec sec-type="disclaimer" id="sec24">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec sec-type="supplementary-material" id="sec25">
<title>Supplementary material</title>
<p>The Supplementary material for this article can be found online at: <ext-link xlink:href="https://www.frontiersin.org/articles/10.3389/fpubh.2025.1746822/full#supplementary-material" ext-link-type="uri">https://www.frontiersin.org/articles/10.3389/fpubh.2025.1746822/full#supplementary-material</ext-link></p>
<supplementary-material xlink:href="Table_1.DOCX" id="SM1" mimetype="application/vnd.openxmlformats-officedocument.wordprocessingml.document" xmlns:xlink="http://www.w3.org/1999/xlink"/>
</sec>
<ref-list>
<title>References</title>
<ref id="ref1"><label>1.</label><mixed-citation publication-type="book"><person-group person-group-type="author"><collab id="coll1">American Psychiatric Association</collab></person-group>. <source>Diagnostic and statistical manual of mental disorders: DSM-5&#x2122;</source>. <edition>5th</edition> ed. <publisher-loc>Arlington, VA, US</publisher-loc>: <publisher-name>American Psychiatric Publishing, Inc.</publisher-name> (<year>2013</year>). <fpage>947-xliv</fpage> p.</mixed-citation></ref>
<ref id="ref2"><label>2.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Patel</surname> <given-names>D</given-names></name> <name><surname>Steinberg</surname> <given-names>J</given-names></name> <name><surname>Patel</surname> <given-names>P</given-names></name></person-group>. <article-title>Insomnia in the elderly: a review</article-title>. <source>J Clin Sleep Med</source>. (<year>2018</year>) <volume>14</volume>:<fpage>1017</fpage>&#x2013;<lpage>24</lpage>. doi: <pub-id pub-id-type="doi">10.5664/jcsm.7172</pub-id>, <pub-id pub-id-type="pmid">29852897</pub-id></mixed-citation></ref>
<ref id="ref3"><label>3.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>de Zambotti</surname> <given-names>M</given-names></name> <name><surname>Goldstone</surname> <given-names>A</given-names></name> <name><surname>Colrain</surname> <given-names>IM</given-names></name> <name><surname>Baker</surname> <given-names>FC</given-names></name></person-group>. <article-title>Insomnia disorder in adolescence: diagnosis, impact, and treatment</article-title>. <source>Sleep Med Rev</source>. (<year>2018</year>) <volume>39</volume>:<fpage>12</fpage>&#x2013;<lpage>24</lpage>. doi: <pub-id pub-id-type="doi">10.1016/j.smrv.2017.06.009</pub-id>, <pub-id pub-id-type="pmid">28974427</pub-id></mixed-citation></ref>
<ref id="ref4"><label>4.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Johnson</surname> <given-names>KA</given-names></name> <name><surname>Gordon</surname> <given-names>CJ</given-names></name> <name><surname>Chapman</surname> <given-names>JL</given-names></name> <name><surname>Hoyos</surname> <given-names>CM</given-names></name> <name><surname>Marshall</surname> <given-names>NS</given-names></name> <name><surname>Miller</surname> <given-names>CB</given-names></name> <etal/></person-group>. <article-title>The association of insomnia disorder characterised by objective short sleep duration with hypertension, diabetes and body mass index: a systematic review and meta-analysis</article-title>. <source>Sleep Med Rev</source>. (<year>2021</year>) <volume>59</volume>:<fpage>101456</fpage>. doi: <pub-id pub-id-type="doi">10.1016/j.smrv.2021.101456</pub-id>, <pub-id pub-id-type="pmid">33640704</pub-id></mixed-citation></ref>
<ref id="ref5"><label>5.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Khan</surname> <given-names>MS</given-names></name> <name><surname>Aouad</surname> <given-names>R</given-names></name></person-group>. <article-title>The effects of insomnia and sleep loss on cardiovascular disease</article-title>. <source>Sleep Med Clin</source>. (<year>2022</year>) <volume>17</volume>:<fpage>193</fpage>&#x2013;<lpage>203</lpage>. doi: <pub-id pub-id-type="doi">10.1016/j.jsmc.2022.02.008</pub-id>, <pub-id pub-id-type="pmid">35659073</pub-id></mixed-citation></ref>
<ref id="ref6"><label>6.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Momin</surname> <given-names>KN</given-names></name> <name><surname>Sheehan</surname> <given-names>C</given-names></name> <name><surname>Samper-Ternent</surname> <given-names>R</given-names></name> <name><surname>L&#x00F3;pez</surname> <given-names>DS</given-names></name> <name><surname>Wong</surname> <given-names>R</given-names></name> <name><surname>Milani</surname> <given-names>SA</given-names></name></person-group>. <article-title>The impact of insomnia symptoms on obesity among Mexicans aged 50 and older</article-title>. <source>Salud Publica Mex</source>. (<year>2023</year>) <volume>65</volume>:<fpage>530</fpage>&#x2013;<lpage>41</lpage>. doi: <pub-id pub-id-type="doi">10.21149/14759</pub-id>, <pub-id pub-id-type="pmid">38060913</pub-id></mixed-citation></ref>
<ref id="ref7"><label>7.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Riemann</surname> <given-names>D</given-names></name> <name><surname>Dressle</surname> <given-names>RJ</given-names></name> <name><surname>Benz</surname> <given-names>F</given-names></name> <name><surname>Spiegelhalder</surname> <given-names>K</given-names></name> <name><surname>Johann</surname> <given-names>AF</given-names></name> <name><surname>Nissen</surname> <given-names>C</given-names></name> <etal/></person-group>. <article-title>Chronic insomnia, REM sleep instability and emotional dysregulation: a pathway to anxiety and depression?</article-title> <source>J Sleep Res</source>. (<year>2025</year>) <volume>34</volume>:<fpage>e14252</fpage>. doi: <pub-id pub-id-type="doi">10.1111/jsr.14252</pub-id>, <pub-id pub-id-type="pmid">38811745</pub-id></mixed-citation></ref>
<ref id="ref8"><label>8.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Shan</surname> <given-names>W</given-names></name> <name><surname>Peng</surname> <given-names>X</given-names></name> <name><surname>Tan</surname> <given-names>W</given-names></name> <name><surname>Zhou</surname> <given-names>Z</given-names></name> <name><surname>Xie</surname> <given-names>H</given-names></name> <name><surname>Wang</surname> <given-names>S</given-names></name></person-group>. <article-title>Prevalence of insomnia and associations with depression, anxiety among adults in Guangdong, China: a large-scale cross-sectional study</article-title>. <source>Sleep Med</source>. (<year>2024</year>) <volume>115</volume>:<fpage>39</fpage>&#x2013;<lpage>47</lpage>. doi: <pub-id pub-id-type="doi">10.1016/j.sleep.2024.01.023</pub-id>, <pub-id pub-id-type="pmid">38330694</pub-id></mixed-citation></ref>
<ref id="ref9"><label>9.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Xu</surname> <given-names>W</given-names></name> <name><surname>Tan</surname> <given-names>CC</given-names></name> <name><surname>Zou</surname> <given-names>JJ</given-names></name> <name><surname>Cao</surname> <given-names>XP</given-names></name> <name><surname>Tan</surname> <given-names>L</given-names></name></person-group>. <article-title>Sleep problems and risk of all-cause cognitive decline or dementia: an updated systematic review and meta-analysis</article-title>. <source>J Neurol Neurosurg Psychiatry</source>. (<year>2020</year>) <volume>91</volume>:<fpage>236</fpage>&#x2013;<lpage>44</lpage>. doi: <pub-id pub-id-type="doi">10.1136/jnnp-2019-321896</pub-id>, <pub-id pub-id-type="pmid">31879285</pub-id></mixed-citation></ref>
<ref id="ref10"><label>10.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Li</surname> <given-names>X</given-names></name> <name><surname>Li</surname> <given-names>H</given-names></name> <name><surname>Gan</surname> <given-names>S</given-names></name> <name><surname>Zhang</surname> <given-names>Y</given-names></name> <name><surname>Yin</surname> <given-names>D</given-names></name> <name><surname>Zhu</surname> <given-names>B</given-names></name> <etal/></person-group>. <article-title>Falls, sleep disorders and cognitive frailty in hospitalized older adults with hypertension:a cross-sectional study</article-title>. <source>Clin Interv Aging</source>. (<year>2025</year>) <volume>20</volume>:<fpage>859</fpage>&#x2013;<lpage>72</lpage>. doi: <pub-id pub-id-type="doi">10.2147/CIA.S510228</pub-id>, <pub-id pub-id-type="pmid">40547364</pub-id></mixed-citation></ref>
<ref id="ref11"><label>11.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lee</surname> <given-names>S</given-names></name> <name><surname>Chung</surname> <given-names>JH</given-names></name> <name><surname>Kim</surname> <given-names>JH</given-names></name></person-group>. <article-title>Association between sleep quality and falls: a Nationwide population-based study from South Korea</article-title>. <source>Int J Gen Med</source>. (<year>2021</year>) <volume>14</volume>:<fpage>7423</fpage>&#x2013;<lpage>33</lpage>. doi: <pub-id pub-id-type="doi">10.2147/IJGM.S331103</pub-id>, <pub-id pub-id-type="pmid">34744453</pub-id></mixed-citation></ref>
<ref id="ref12"><label>12.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Liu</surname> <given-names>X</given-names></name> <name><surname>Wang</surname> <given-names>C</given-names></name> <name><surname>Qiao</surname> <given-names>X</given-names></name> <name><surname>Si</surname> <given-names>H</given-names></name> <name><surname>Jin</surname> <given-names>Y</given-names></name></person-group>. <article-title>Sleep quality, depression and frailty among Chinese community-dwelling older adults</article-title>. <source>Geriatr Nurs</source>. (<year>2021</year>) <volume>42</volume>:<fpage>714</fpage>&#x2013;<lpage>20</lpage>. doi: <pub-id pub-id-type="doi">10.1016/j.gerinurse.2021.02.020</pub-id>, <pub-id pub-id-type="pmid">33836251</pub-id></mixed-citation></ref>
<ref id="ref13"><label>13.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Riemann</surname> <given-names>D</given-names></name> <name><surname>Benz</surname> <given-names>F</given-names></name> <name><surname>Dressle</surname> <given-names>RJ</given-names></name> <name><surname>Espie</surname> <given-names>CA</given-names></name> <name><surname>Johann</surname> <given-names>AF</given-names></name> <name><surname>Blanken</surname> <given-names>TF</given-names></name> <etal/></person-group>. <article-title>Insomnia disorder: state of the science and challenges for the future</article-title>. <source>J Sleep Res</source>. (<year>2022</year>) <volume>31</volume>:<fpage>e13604</fpage>. doi: <pub-id pub-id-type="doi">10.1111/jsr.13604</pub-id>, <pub-id pub-id-type="pmid">35460140</pub-id></mixed-citation></ref>
<ref id="ref14"><label>14.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Luyster</surname> <given-names>FS</given-names></name> <name><surname>Boudreaux-Kelly</surname> <given-names>MY</given-names></name> <name><surname>Bon</surname> <given-names>JM</given-names></name></person-group>. <article-title>Insomnia in chronic obstructive pulmonary disease and associations with healthcare utilization and costs</article-title>. <source>Respir Res</source>. (<year>2023</year>) <volume>24</volume>:<fpage>93</fpage>. doi: <pub-id pub-id-type="doi">10.1186/s12931-023-02401-w</pub-id>, <pub-id pub-id-type="pmid">36964552</pub-id></mixed-citation></ref>
<ref id="ref15"><label>15.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Yang</surname> <given-names>JJ</given-names></name> <name><surname>Cai</surname> <given-names>H</given-names></name> <name><surname>Xia</surname> <given-names>L</given-names></name> <name><surname>Nie</surname> <given-names>W</given-names></name> <name><surname>Zhang</surname> <given-names>Y</given-names></name> <name><surname>Wang</surname> <given-names>S</given-names></name> <etal/></person-group>. <article-title>The prevalence of depressive and insomnia symptoms, and their association with quality of life among older adults in rural areas in China</article-title>. <source>Front Psych</source>. (<year>2021</year>) <volume>12</volume>:<fpage>727939</fpage>. doi: <pub-id pub-id-type="doi">10.3389/fpsyt.2021.727939</pub-id>, <pub-id pub-id-type="pmid">34658962</pub-id></mixed-citation></ref>
<ref id="ref16"><label>16.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Meaklim</surname> <given-names>H</given-names></name> <name><surname>Le</surname> <given-names>F</given-names></name> <name><surname>Drummond</surname> <given-names>SPA</given-names></name> <name><surname>Bains</surname> <given-names>SK</given-names></name> <name><surname>Varma</surname> <given-names>P</given-names></name> <name><surname>Junge</surname> <given-names>MF</given-names></name> <etal/></person-group>. <article-title>Insomnia is more likely to persist than remit after a time of stress and uncertainty: a longitudinal cohort study examining trajectories and predictors of insomnia symptoms</article-title>. <source>Sleep</source>. (<year>2024</year>) <volume>47</volume>:<fpage>zsae028</fpage>. doi: <pub-id pub-id-type="doi">10.1093/sleep/zsae028</pub-id>, <pub-id pub-id-type="pmid">38308584</pub-id></mixed-citation></ref>
<ref id="ref17"><label>17.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Riemann</surname> <given-names>D</given-names></name> <name><surname>Baglioni</surname> <given-names>C</given-names></name> <name><surname>Bassetti</surname> <given-names>C</given-names></name> <name><surname>Bjorvatn</surname> <given-names>B</given-names></name> <name><surname>Dolenc Groselj</surname> <given-names>L</given-names></name> <name><surname>Ellis</surname> <given-names>JG</given-names></name> <etal/></person-group>. <article-title>European guideline for the diagnosis and treatment of insomnia</article-title>. <source>J Sleep Res</source>. (<year>2017</year>) <volume>26</volume>:<fpage>675</fpage>&#x2013;<lpage>700</lpage>. doi: <pub-id pub-id-type="doi">10.1111/jsr.12594</pub-id>, <pub-id pub-id-type="pmid">28875581</pub-id></mixed-citation></ref>
<ref id="ref18"><label>18.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sutton</surname> <given-names>EL</given-names></name></person-group>. <article-title>Insomnia</article-title>. <source>Ann Intern Med</source>. (<year>2021</year>) <volume>174</volume>:<fpage>ITC33</fpage>&#x2013;<lpage>48</lpage>. doi: <pub-id pub-id-type="doi">10.7326/AITC202103160</pub-id>, <pub-id pub-id-type="pmid">33683929</pub-id></mixed-citation></ref>
<ref id="ref19"><label>19.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hu</surname> <given-names>S</given-names></name> <name><surname>Chen</surname> <given-names>Y</given-names></name> <name><surname>Sun</surname> <given-names>Q</given-names></name> <name><surname>Zhang</surname> <given-names>A</given-names></name> <name><surname>Lou</surname> <given-names>S</given-names></name> <name><surname>Chen</surname> <given-names>Q</given-names></name> <etal/></person-group>. <article-title>Cognitive behavioral therapy for insomnia in China: a knowledge, attitude, and practice study among medical doctors treating patients with insomnia</article-title>. <source>Behav Sleep Med</source>. (<year>2025</year>):<fpage>1</fpage>&#x2013;<lpage>10</lpage>. doi: <pub-id pub-id-type="doi">10.1080/15402002.2024.2449354</pub-id></mixed-citation></ref>
<ref id="ref20"><label>20.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Man</surname> <given-names>J</given-names></name> <name><surname>Yan</surname> <given-names>R</given-names></name> <name><surname>Yang</surname> <given-names>K</given-names></name> <name><surname>Ouyang</surname> <given-names>Y</given-names></name> <name><surname>Shu</surname> <given-names>C</given-names></name> <name><surname>Sun</surname> <given-names>J</given-names></name> <etal/></person-group>. <article-title>Cognitive behavioral therapy in China: practices and exploration</article-title>. <source>Int J Cogn Ther</source>. (<year>2024</year>) <volume>17</volume>:<fpage>231</fpage>&#x2013;<lpage>50</lpage>. doi: <pub-id pub-id-type="doi">10.1007/s41811-024-00203-6</pub-id></mixed-citation></ref>
<ref id="ref21"><label>21.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Zhang</surname> <given-names>C</given-names></name> <name><surname>Liu</surname> <given-names>Y</given-names></name> <name><surname>Guo</surname> <given-names>X</given-names></name> <name><surname>Liu</surname> <given-names>Y</given-names></name> <name><surname>Shen</surname> <given-names>Y</given-names></name> <name><surname>Ma</surname> <given-names>J</given-names></name></person-group>. <article-title>Digital cognitive behavioral therapy for insomnia using a smartphone application in China: a pilot randomized clinical trial</article-title>. <source>JAMA Netw Open</source>. (<year>2023</year>) <volume>6</volume>:<fpage>e234866</fpage>. doi: <pub-id pub-id-type="doi">10.1001/jamanetworkopen.2023.4866</pub-id>, <pub-id pub-id-type="pmid">36972049</pub-id></mixed-citation></ref>
<ref id="ref22"><label>22.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Abad</surname> <given-names>VC</given-names></name> <name><surname>Guilleminault</surname> <given-names>C</given-names></name></person-group>. <article-title>Insomnia in elderly patients: recommendations for pharmacological management</article-title>. <source>Drugs Aging</source>. (<year>2018</year>) <volume>35</volume>:<fpage>791</fpage>&#x2013;<lpage>817</lpage>. doi: <pub-id pub-id-type="doi">10.1007/s40266-018-0569-8</pub-id>, <pub-id pub-id-type="pmid">30058034</pub-id></mixed-citation></ref>
<ref id="ref23"><label>23.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Tuft</surname> <given-names>C</given-names></name> <name><surname>Matar</surname> <given-names>E</given-names></name> <name><surname>Menczel Schrire</surname> <given-names>Z</given-names></name> <name><surname>Grunstein</surname> <given-names>RR</given-names></name> <name><surname>Yee</surname> <given-names>BJ</given-names></name> <name><surname>Hoyos</surname> <given-names>CM</given-names></name></person-group>. <article-title>Current insights into the risks of using melatonin as a treatment for sleep disorders in older adults</article-title>. <source>Clin Interv Aging</source>. (<year>2023</year>) <volume>18</volume>:<fpage>49</fpage>&#x2013;<lpage>59</lpage>. doi: <pub-id pub-id-type="doi">10.2147/CIA.S361519</pub-id>, <pub-id pub-id-type="pmid">36660543</pub-id></mixed-citation></ref>
<ref id="ref24"><label>24.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sun</surname> <given-names>L</given-names></name> <name><surname>Li</surname> <given-names>K</given-names></name> <name><surname>Zhang</surname> <given-names>Y</given-names></name> <name><surname>Zhang</surname> <given-names>L</given-names></name></person-group>. <article-title>Sleep-related healthcare use prevalence among adults with insomnia symptoms in Hebei, China: a population-based cross-sectional study</article-title>. <source>BMJ Open</source>. (<year>2022</year>) <volume>12</volume>:<fpage>e057331</fpage>. doi: <pub-id pub-id-type="doi">10.1136/bmjopen-2021-057331</pub-id>, <pub-id pub-id-type="pmid">35977764</pub-id></mixed-citation></ref>
<ref id="ref25"><label>25.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Duan</surname> <given-names>Y</given-names></name> <name><surname>Wang</surname> <given-names>Y</given-names></name> <name><surname>Yang</surname> <given-names>H</given-names></name> <name><surname>Cai</surname> <given-names>Y</given-names></name> <name><surname>Wu</surname> <given-names>S</given-names></name> <name><surname>Zhao</surname> <given-names>P</given-names></name> <etal/></person-group>. <article-title>Protocol for the practice guideline for traditional Chinese medicine preventive treatment on insomnia disorder</article-title>. <source>Front Psych</source>. (<year>2025</year>) <volume>16</volume>:<fpage>1475904</fpage>. doi: <pub-id pub-id-type="doi">10.3389/fpsyt.2025.1475904</pub-id>, <pub-id pub-id-type="pmid">40309501</pub-id></mixed-citation></ref>
<ref id="ref26"><label>26.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Zhang</surname> <given-names>S</given-names></name> <name><surname>Li</surname> <given-names>Y</given-names></name> <name><surname>Liang</surname> <given-names>Z</given-names></name> <name><surname>Dai</surname> <given-names>J</given-names></name> <name><surname>Huang</surname> <given-names>H</given-names></name> <name><surname>Zhang</surname> <given-names>H</given-names></name> <etal/></person-group>. <article-title>Comparing the effects of different non-pharmacological traditional Chinese medicine therapies on cancer survivors: a Bayesian network Meta-analysis</article-title>. <source>Complement Ther Med</source>. (<year>2025</year>) <volume>90</volume>:<fpage>103164</fpage>. doi: <pub-id pub-id-type="doi">10.1016/j.ctim.2025.103164</pub-id>, <pub-id pub-id-type="pmid">40157553</pub-id></mixed-citation></ref>
<ref id="ref27"><label>27.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Liu</surname> <given-names>W</given-names></name> <name><surname>Jing</surname> <given-names>R</given-names></name></person-group>. <article-title>Efficacy and safety of TCM non-pharmacologic therapy for post-stroke insomnia: a systematic review and network meta-analysis</article-title>. <source>Sleep Breath</source>. (<year>2025</year>) <volume>29</volume>:<fpage>199</fpage>. doi: <pub-id pub-id-type="doi">10.1007/s11325-025-03357-5</pub-id>, <pub-id pub-id-type="pmid">40448739</pub-id></mixed-citation></ref>
<ref id="ref28"><label>28.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Wang</surname> <given-names>J</given-names></name> <name><surname>Zhao</surname> <given-names>H</given-names></name> <name><surname>Shi</surname> <given-names>K</given-names></name> <name><surname>Wang</surname> <given-names>M</given-names></name></person-group>. <article-title>Treatment of insomnia based on the mechanism of pathophysiology by acupuncture combined with herbal medicine: a review</article-title>. <source>Medicine (Baltimore)</source>. (<year>2023</year>) <volume>102</volume>:<fpage>e33213</fpage>. doi: <pub-id pub-id-type="doi">10.1097/MD.0000000000033213</pub-id>, <pub-id pub-id-type="pmid">36930068</pub-id></mixed-citation></ref>
<ref id="ref29"><label>29.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ye</surname> <given-names>Z</given-names></name> <name><surname>Lai</surname> <given-names>H</given-names></name> <name><surname>Ning</surname> <given-names>J</given-names></name> <name><surname>Liu</surname> <given-names>J</given-names></name> <name><surname>Huang</surname> <given-names>J</given-names></name> <name><surname>Yang</surname> <given-names>S</given-names></name> <etal/></person-group>. <article-title>Traditional Chinese medicine for insomnia: recommendation mapping of the global clinical guidelines</article-title>. <source>J Ethnopharmacol</source>. (<year>2024</year>) <volume>322</volume>:<fpage>117601</fpage>. doi: <pub-id pub-id-type="doi">10.1016/j.jep.2023.117601</pub-id>, <pub-id pub-id-type="pmid">38122913</pub-id></mixed-citation></ref>
<ref id="ref30"><label>30.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Xu</surname> <given-names>C</given-names></name> <name><surname>Yin</surname> <given-names>DH</given-names></name> <name><surname>Han</surname> <given-names>JH</given-names></name> <name><surname>Gao</surname> <given-names>YN</given-names></name> <name><surname>Li</surname> <given-names>XH</given-names></name> <name><surname>Wang</surname> <given-names>XJ</given-names></name></person-group>. <article-title>Efficacy of traditional Chinese medicine external therapies in treating insomnia in patients with chronic hepatitis B: systematic review and Meta-analysis</article-title>. <source>J Viral Hepat</source>. (<year>2025</year>) <volume>32</volume>:<fpage>e70030</fpage>. doi: <pub-id pub-id-type="doi">10.1111/jvh.70030</pub-id>, <pub-id pub-id-type="pmid">40332371</pub-id></mixed-citation></ref>
<ref id="ref31"><label>31.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lederle</surname> <given-names>M</given-names></name> <name><surname>Tempes</surname> <given-names>J</given-names></name> <name><surname>Bitzer</surname> <given-names>EM</given-names></name></person-group>. <article-title>Application of Andersen's behavioural model of health services use: a scoping review with a focus on qualitative health services research</article-title>. <source>BMJ Open</source>. (<year>2021</year>) <volume>11</volume>:<fpage>e045018</fpage>. doi: <pub-id pub-id-type="doi">10.1136/bmjopen-2020-045018</pub-id>, <pub-id pub-id-type="pmid">33952550</pub-id></mixed-citation></ref>
<ref id="ref32"><label>32.</label><mixed-citation publication-type="book"><person-group person-group-type="author"><name><surname>Morin</surname> <given-names>CM</given-names></name></person-group>. <source>Insomnia: Psychological assessment and management</source>. <publisher-loc>New York</publisher-loc>: <publisher-name>Guilford Press</publisher-name> (<year>1993</year>).</mixed-citation></ref>
<ref id="ref33"><label>33.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bastien</surname> <given-names>CH</given-names></name> <name><surname>Valli&#x00E8;res</surname> <given-names>A</given-names></name> <name><surname>Morin</surname> <given-names>CM</given-names></name></person-group>. <article-title>Validation of the insomnia severity index as an outcome measure for insomnia research</article-title>. <source>Sleep Med</source>. (<year>2001</year>) <volume>2</volume>:<fpage>297</fpage>&#x2013;<lpage>307</lpage>. doi: <pub-id pub-id-type="doi">10.1016/S1389-9457(00)00065-4</pub-id>, <pub-id pub-id-type="pmid">11438246</pub-id></mixed-citation></ref>
<ref id="ref34"><label>34.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Morin</surname> <given-names>CM</given-names></name> <name><surname>Belleville</surname> <given-names>G</given-names></name> <name><surname>B&#x00E9;langer</surname> <given-names>L</given-names></name> <name><surname>Ivers</surname> <given-names>H</given-names></name></person-group>. <article-title>The insomnia severity index: psychometric indicators to detect insomnia cases and evaluate treatment response</article-title>. <source>Sleep</source>. (<year>2011</year>) <volume>34</volume>:<fpage>601</fpage>&#x2013;<lpage>8</lpage>. doi: <pub-id pub-id-type="doi">10.1093/sleep/34.5.601</pub-id>, <pub-id pub-id-type="pmid">21532953</pub-id></mixed-citation></ref>
<ref id="ref35"><label>35.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Yang</surname> <given-names>M</given-names></name> <name><surname>Morin</surname> <given-names>CM</given-names></name> <name><surname>Schaefer</surname> <given-names>K</given-names></name> <name><surname>Wallenstein</surname> <given-names>GV</given-names></name></person-group>. <article-title>Interpreting score differences in the insomnia severity index: using health-related outcomes to define the minimally important difference</article-title>. <source>Curr Med Res Opin</source>. (<year>2009</year>) <volume>25</volume>:<fpage>2487</fpage>&#x2013;<lpage>94</lpage>. doi: <pub-id pub-id-type="doi">10.1185/03007990903167415</pub-id>, <pub-id pub-id-type="pmid">19689221</pub-id></mixed-citation></ref>
<ref id="ref36"><label>36.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Yan</surname> <given-names>C</given-names></name> <name><surname>Dequan</surname> <given-names>S</given-names></name> <name><surname>Renlei</surname> <given-names>S</given-names></name> <name><surname>Yujie</surname> <given-names>C</given-names></name> <name><surname>Jiaqi</surname> <given-names>Y</given-names></name> <name><surname>Jie</surname> <given-names>D</given-names></name> <etal/></person-group>. <article-title>The importance of factors influencing elderly using of preventive services of traditional Chinese medicine</article-title>. <source>Chin Gen Pract</source>. (<year>2024</year>) <volume>1</volume>:<fpage>100031</fpage>. doi: <pub-id pub-id-type="doi">10.1016/j.cgpj.2024.10.004</pub-id></mixed-citation></ref>
<ref id="ref37"><label>37.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Peduzzi</surname> <given-names>P</given-names></name> <name><surname>Concato</surname> <given-names>J</given-names></name> <name><surname>Kemper</surname> <given-names>E</given-names></name> <name><surname>Holford</surname> <given-names>TR</given-names></name> <name><surname>Feinstein</surname> <given-names>AR</given-names></name></person-group>. <article-title>A simulation study of the number of events per variable in logistic regression analysis</article-title>. <source>J Clin Epidemiol</source>. (<year>1996</year>) <volume>49</volume>:<fpage>1373</fpage>&#x2013;<lpage>9</lpage>. doi: <pub-id pub-id-type="doi">10.1016/S0895-4356(96)00236-3</pub-id>, <pub-id pub-id-type="pmid">8970487</pub-id></mixed-citation></ref>
<ref id="ref38"><label>38.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Zhang</surname> <given-names>H</given-names></name> <name><surname>Zhang</surname> <given-names>Y</given-names></name> <name><surname>Yan</surname> <given-names>Y</given-names></name> <name><surname>Li</surname> <given-names>X</given-names></name> <name><surname>Tian</surname> <given-names>Y</given-names></name></person-group>. <article-title>Traditional Chinese medicine health literacy among rural older adults: a cross-sectional study</article-title>. <source>Front Public Health</source>. (<year>2024</year>) <volume>12</volume>:<fpage>1361572</fpage>. doi: <pub-id pub-id-type="doi">10.3389/fpubh.2024.1361572</pub-id>, <pub-id pub-id-type="pmid">38827610</pub-id></mixed-citation></ref>
<ref id="ref39"><label>39.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ng</surname> <given-names>TKC</given-names></name> <name><surname>Lo</surname> <given-names>MF</given-names></name> <name><surname>Fong</surname> <given-names>BYF</given-names></name> <name><surname>Yee</surname> <given-names>HHL</given-names></name></person-group>. <article-title>Predictors of the intention to use traditional Chinese medicine (TCM) using extended theory of planned behavior: a cross-sectional study among TCM users in Hong Kong</article-title>. <source>BMC Complementary Med Therapies</source>. (<year>2022</year>) <volume>22</volume>:<fpage>113</fpage>. doi: <pub-id pub-id-type="doi">10.1186/s12906-022-03598-x</pub-id>, <pub-id pub-id-type="pmid">35459198</pub-id></mixed-citation></ref>
<ref id="ref40"><label>40.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Eigenschink</surname> <given-names>M</given-names></name> <name><surname>Bellach</surname> <given-names>L</given-names></name> <name><surname>Leonard</surname> <given-names>S</given-names></name> <name><surname>Dablander</surname> <given-names>TE</given-names></name> <name><surname>Maier</surname> <given-names>J</given-names></name> <name><surname>Dablander</surname> <given-names>F</given-names></name> <etal/></person-group>. <article-title>Cross-sectional survey and Bayesian network model analysis of traditional Chinese medicine in Austria: investigating public awareness, usage determinants and perception of scientific support</article-title>. <source>BMJ Open</source>. (<year>2023</year>) <volume>13</volume>:<fpage>e060644</fpage>. doi: <pub-id pub-id-type="doi">10.1136/bmjopen-2021-060644</pub-id>, <pub-id pub-id-type="pmid">36863740</pub-id></mixed-citation></ref>
<ref id="ref41"><label>41.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Yu</surname> <given-names>DS</given-names></name></person-group>. <article-title>Insomnia severity index: psychometric properties with Chinese community-dwelling older people</article-title>. <source>J Adv Nurs</source>. (<year>2010</year>) <volume>66</volume>:<fpage>2350</fpage>&#x2013;<lpage>9</lpage>. doi: <pub-id pub-id-type="doi">10.1111/j.1365-2648.2010.05394.x</pub-id>, <pub-id pub-id-type="pmid">20722803</pub-id></mixed-citation></ref>
<ref id="ref42"><label>42.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Dales</surname> <given-names>LG</given-names></name> <name><surname>Ury</surname> <given-names>HK</given-names></name></person-group>. <article-title>An improper use of statistical significance testing in studying covariables</article-title>. <source>Int J Epidemiol</source>. (<year>1978</year>) <volume>7</volume>:<fpage>373</fpage>&#x2013;<lpage>5</lpage>. doi: <pub-id pub-id-type="doi">10.1093/ije/7.4.373</pub-id>, <pub-id pub-id-type="pmid">744677</pub-id></mixed-citation></ref>
<ref id="ref43"><label>43.</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Tian</surname> <given-names>G</given-names></name> <name><surname>Zhao</surname> <given-names>C</given-names></name> <name><surname>Zhang</surname> <given-names>X</given-names></name> <name><surname>Mu</surname> <given-names>W</given-names></name> <name><surname>Jiang</surname> <given-names>Y</given-names></name> <name><surname>Wei</surname> <given-names>X</given-names></name> <etal/></person-group>. <article-title>Evidence-based traditional Chinese medicine research: two decades of development, its impact, and breakthrough</article-title>. <source>J Evid Based Med</source>. (<year>2021</year>) <volume>14</volume>:<fpage>65</fpage>&#x2013;<lpage>74</lpage>. doi: <pub-id pub-id-type="doi">10.1111/jebm.12420</pub-id>, <pub-id pub-id-type="pmid">33615709</pub-id></mixed-citation></ref>
</ref-list>
<fn-group>
<fn fn-type="custom" custom-type="edited-by" id="fn0002">
<p>Edited by: <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/252300/overview">Mika Venoj&#x00E4;rvi</ext-link>, University of Eastern Finland, Finland</p>
</fn>
<fn fn-type="custom" custom-type="reviewed-by" id="fn0003">
<p>Reviewed by: <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/26364/overview">David Neubauer</ext-link>, Johns Hopkins University, United States</p>
<p><ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/2107381/overview">Duy-Thai Nguyen</ext-link>, NICVB, Ministry of Health, Vietnam</p>
</fn>
</fn-group>
</back>
</article>