AUTHOR=Zhou Yu-Mei , Xiong Xiao-Wan , Zhou Han , Ma Xiao-Ming , Yan Bing , Qiu Jiang-Ning , Chen Xiao-Yi , Zhang Liu-Juan , Wei Yan-Fang , Zheng Xiao-Bing , Li Lin-Qing , Chen Shao-Jun , Xu Yin-Li , Han Si-Yi , Lin Yu-Fen , Xu Yu-Qin , Gou Yan-Hua 

TITLE=Efficacy of internet-based peer education for postpartum depression: study protocol of a randomized controlled trial

JOURNAL=Frontiers in Public Health

VOLUME=Volume 13 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1630303

DOI=10.3389/fpubh.2025.1630303

ISSN=2296-2565

ABSTRACT=IntroductionPostpartum depression (PPD) is widely and profoundly affecting family and social stability. But now the consultation rate of overall PPD population is still not ideal for practical reasons. This study observes the effectiveness of Internet-based peer education, a promising treatment approach that may effectively and fairly serve the PPD group, so as to benefit more people in the future.ObjectivesThis study integrates internet-based peer education to serve PPD groups effectively and equitably, aiming to benefit more people. It explores IPE’s efficacy vs. RHE in reducing symptom severity at 6-week intervention and 16-week follow-up.MethodsThis study is a randomized, parallel, and controlled trial, consist of a 6-week treatment period along with a 12-week follow-up period. Eighty-eight patients diagnosed as PPD will be recruited. They will be randomly assigned to one of two groups, internet-based peer education (IPE) group and regular health education (RHE) group, in a 1:1 ratio. Both groups will receive RHE along the 6-week treatment, while subjects in IPE group will receive 6-week online peer education additionally. The primary outcome is the response rate based on scores of 17-item Hamilton Depression Rating Scale at the week 6 and 12. The secondary outcomes include Edinburgh Postpartum Depression Scale (EPDS), World Health Organization Quality of Life Scale Brief (WHOQOL-BREF) and Self-Efficacy to Manage Chronic Disease Scale (SEMCD). All these scales will be evaluated at baseline, 1, 2, 4, 6, and 12 weeks after the initiation of intervention.ConclusionThe results of this RCT on Internet-based peer education for postpartum depression will provide an assessment of the feasibility of the protocol and data for power calculations to inform the development of a larger scale trial.