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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Public Health</journal-id>
<journal-title>Frontiers in Public Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Public Health</abbrev-journal-title>
<issn pub-type="epub">2296-2565</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpubh.2024.1487789</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Public Health</subject>
<subj-group>
<subject>Systematic Review</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Effects of high intensity interval training and moderate intensity continuous training on enjoyment and affective responses in overweight or obese people: a meta-analysis</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name><surname>Luo</surname> <given-names>Yang</given-names></name>
<uri xlink:href="https://loop.frontiersin.org/people/2828891/overview"/>
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<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Zhang</surname> <given-names>Junshuai</given-names></name>
<role content-type="https://credit.niso.org/contributor-roles/conceptualization/"/>
<role content-type="https://credit.niso.org/contributor-roles/supervision/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Jia</surname> <given-names>Haichang</given-names></name>
<uri xlink:href="https://loop.frontiersin.org/people/2864980/overview"/>
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</contrib>
<contrib contrib-type="author">
<name><surname>Mu</surname> <given-names>Xintong</given-names></name>
<role content-type="https://credit.niso.org/contributor-roles/conceptualization/"/>
<role content-type="https://credit.niso.org/contributor-roles/supervision/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name><surname>Huang</surname> <given-names>Jing</given-names></name>
<xref ref-type="corresp" rid="c001"><sup>&#x002A;</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/2389007/overview"/>
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</contrib>
</contrib-group>
<aff><institution>College of Physical Education, Southwest University</institution>, <addr-line>Chongqing</addr-line>, <country>China</country></aff>
<author-notes>
<fn fn-type="edited-by" id="fn0001">
<p>Edited by: Frauke Musial, UiT The Arctic University of Norway, Norway</p></fn>
<fn fn-type="edited-by" id="fn0002">
<p>Reviewed by: Vagner Deuel De Oliveira Tavares, Federal University of Rio Grande do Norte, Brazil</p>
<p>Wissal Abassi, University of Jendouba, Tunisia</p>
<p>Sujata Shakya, Tampere University, Finland</p></fn>
<corresp id="c001">&#x002A;Correspondence: Jing Huang, <email>327743382@qq.com</email></corresp>
</author-notes>
<pub-date pub-type="epub">
<day>29</day>
<month>11</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="collection">
<year>2024</year>
</pub-date>
<volume>12</volume>
<elocation-id>1487789</elocation-id>
<history>
<date date-type="received">
<day>28</day>
<month>08</month>
<year>2024</year>
</date>
<date date-type="accepted">
<day>18</day>
<month>11</month>
<year>2024</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2024 Luo, Zhang, Jia, Mu and Huang.</copyright-statement>
<copyright-year>2024</copyright-year>
<copyright-holder>Luo, Zhang, Jia, Mu and Huang</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<sec id="sec1">
<title>Background</title>
<p>High-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) have demonstrated significant potential for enhancing physical and mental health. However, their respective effects on enjoyment and affective responses remain contentious.</p>
</sec>
<sec id="sec2">
<title>Objective</title>
<p>The objective of this meta-analysis is to evaluate and compare the effectiveness of HIIT and MICT on enjoyment and affective responses in overweight or obese people, and to find the most appropriate exercise mode for overweight or obese people.</p>
</sec>
<sec id="sec3">
<title>Materials and methods</title>
<p>This study was conducted following PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. A comprehensive search was performed across databases including Cochrane, EMBASE, PubMed, and Web of Science, with a cutoff date of August 2024. Data extraction and organization were carried out using Excel, and Review manager was used to evaluate the quality of the literature and to analyze and process the data. The Stata was used to test publication bias.</p>
</sec>
<sec id="sec4">
<title>Results</title>
<p>A total of 16 articles were included in the literature, and a total of 537 participants met the inclusion criteria, including 213 participants in HIIT, 183 participants in MICT, 84 participants in alternating HIIT and MICT, and 57 participants in other forms of intervention (self-selected intensity exercise, very-high-intensity interval exercise, repetitive sprint training, and blank control). All study participants were between the ages of 18&#x2013;70&#x202F;years old, and the duration of the intervention ranged from 1 to 16&#x202F;weeks. Enjoyment and affective effects of HIIT and MICT were analyzed using the Physical Activity Enjoyment Scale, Feeling Scale and Felt Arousal Scale.</p>
</sec>
<sec id="sec5">
<title>Conclusion</title>
<p>Both HIIT and MICT can bring about similar enjoyable and positive affective responses in overweight and obese people, HIIT caused participants to experience higher enjoyment and similar affect responses compared to MICT.</p>
</sec>
</abstract>
<kwd-group>
<kwd>affect</kwd>
<kwd>enjoyment</kwd>
<kwd>overweight</kwd>
<kwd>obese</kwd>
<kwd>high intensity interval training</kwd>
<kwd>moderate intensity continuous training</kwd>
</kwd-group>
<counts>
<fig-count count="8"/>
<table-count count="3"/>
<equation-count count="0"/>
<ref-count count="55"/>
<page-count count="14"/>
<word-count count="7718"/>
</counts>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Public Mental Health</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="sec6">
<label>1</label>
<title>Introduction</title>
<p>Overweight and obesity have emerged as a global &#x201C;epidemic.&#x201D; By 2022, it was estimated that 43% of adults aged 18 and older were classified as overweight, with 16% classified as obese (<xref ref-type="bibr" rid="ref1">1</xref>). The average body mass index (BMI) of the global population is gradually increasing. With the average body mass index of the global population gradually increasing, overweight and obesity have become a public health crisis. It has placed a huge burden on the healthcare and economic systems of both developed and developing countries (<xref ref-type="bibr" rid="ref2">2</xref>). According to the World Obesity Alliance (2024), the fight against obesity requires significant financial investment, and by 2035, high BMI will result in a reduction of more than $4 trillion in the global economy, nearly 3% of global GDP (Gross Domestic Product) (<xref ref-type="bibr" rid="ref3">3</xref>). Overweight and obesity also bring poor physical and mental health to patients, they not only increase the risk of type 2 diabetes and heart disease, affect bone health and reproductive system, but also may raise the risk of certain cancers (<xref ref-type="bibr" rid="ref4">4</xref>). In addition, people who are overweight and obese show poorer mental health outcomes (<xref ref-type="bibr" rid="ref5">5</xref>). Extensive epidemiological research has established a link between high body weight and deteriorating mental health, particularly concerning depression and subclinical depressive symptoms (<xref ref-type="bibr" rid="ref6">6</xref>). Psychological stress induced by weight stigma and discrimination can lead to psychological distress and may, in turn, impede weight management efforts (<xref ref-type="bibr" rid="ref7">7</xref>).</p>
<p>The main treatments available for overweight or obesity are nonoperative management and bariatric surgery, with nonoperative management being a multimodal approach that includes dietary changes, increased physical activity, behavioral changes, and medications (<xref ref-type="bibr" rid="ref8">8</xref>). Among them physical activity is an effective means of weight loss and health management with fewer side effects and adapted to most populations., it can prevent weight gain, reduce weight loss, minimize weight regain after weight loss, and reduce the chances of developing chronic diseases (<xref ref-type="bibr" rid="ref9">9</xref>). Research shows that exercise requires long-term persistence, and affective responses may be predictors of exercise adherence (<xref ref-type="bibr" rid="ref10">10</xref>). Feelings of pleasure and enjoyment are key factors in adherence to an exercise program, and an increase or decrease in pleasure may contribute to the likelihood of forming positive or negative exercise memory traces. This in turn affects their subsequent decisions to participate in, persist with, or withdraw from exercise (<xref ref-type="bibr" rid="ref11">11</xref>). William et al. also mentioned in his study that the core potency response (i.e., pleasure/displeasure) experienced during exercise has been identified as a key determinant of future physical activity behavior, especially for overweight or sedentary adults, who are most in need of interventions to enhance adherence to exercise programs (<xref ref-type="bibr" rid="ref12">12</xref>). Some obese and overweight people may have difficulty maintaining long-term adherence due to weight stigma, self-rejection, or low - and moderate-intensity exercise that is monotonous and non-stimulating, and thus stop exercising after a period of exercise because they cannot stick to it (<xref ref-type="bibr" rid="ref13">13</xref>, <xref ref-type="bibr" rid="ref14">14</xref>). This led us to consider the relationship between obesity and emotional response to exercise. What kind of exercise can give obese and overweight people a good sense of enjoyment and affective response, so that they can keep exercising?</p>
<p>When it comes to physical activity modality choices, there is a wealth of research that proves that high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) are effective modalities of exercise for improving body composition (<xref ref-type="bibr" rid="ref15">15</xref>, <xref ref-type="bibr" rid="ref16">16</xref>). They are effective in improving health and fitness parameters (<xref ref-type="bibr" rid="ref17">17</xref>, <xref ref-type="bibr" rid="ref18">18</xref>). For example, one mate-analysis showed that low-volume HIIT (LV-HIIT; i.e., &#x2264;5&#x202F;min high-intensity exercise within a&#x202F;&#x2264; 15&#x202F;min session) can have similar effects on cardiometabolic health and body composition as MICT and high-volume HIIT, such as in terms of blood pressure, fat mass and waist circumferences (<xref ref-type="bibr" rid="ref19">19</xref>). It is also proved that HIIT once a week, even with low weekly activity, can improve cardiorespiratory fitness, body composition, and blood pressure in overweight or obese adults (<xref ref-type="bibr" rid="ref20">20</xref>). However, the research on assessing affective or pleasurable responses to HIIT and MICT has been largely ambiguous, no matter what kind of population they are in (<xref ref-type="bibr" rid="ref21">21</xref>). For example, study by Niven et al. concluded that compared to MICT, HIIT is experienced less positively but post-exercise is reported to be more enjoyable (<xref ref-type="bibr" rid="ref22">22</xref>). While study by Oliveira et al. (<xref ref-type="bibr" rid="ref23">23</xref>) suggested that HIIT may garner equal or more positive psychological responses than MICT (<xref ref-type="bibr" rid="ref23">23</xref>). In present review we attempted to update more precisely describe participants&#x2019; affective responses to HIIT and MICT. At the same time, HIIT leads to similar or better physiological and biochemical effects than MICT, but takes less time (<xref ref-type="bibr" rid="ref20">20</xref>, <xref ref-type="bibr" rid="ref24">24</xref>, <xref ref-type="bibr" rid="ref25">25</xref>). This provides a new direction and a new way of thinking about the barriers to physical activity in overweight or obese patients, i.e., insufficient time to maintain physical activity levels, and is a good prescription for a &#x201C;short and fast&#x201D; way to promote physical activity (<xref ref-type="bibr" rid="ref26">26</xref>).</p>
<p>Some previous systematic reviews and meta-analysis investigated affective and enjoyment responses to HIIT and MICT have not distinguished obese and overweight people from the general population. Thus, the purpose of this study is to try to find which type of exercise brings better emotional and pleasurable experiences to obese and overweight people and whether HIIT is a better form of exercise for obese people than MICT. Through a systematic review and meta-analysis of the existing literature, to provide new ideas for the selection of exercise prescription for weight loss.</p>
</sec>
<sec sec-type="materials|methods" id="sec7">
<label>2</label>
<title>Materials and methods</title>
<sec id="sec8">
<label>2.1</label>
<title>Literature retrieval</title>
<p>The study was conducted in accordance with the Cochrane Handbook for Systematic Reviews of Interventions and the PRISMA Statement for Systematic Evaluation (<xref ref-type="bibr" rid="ref27">27</xref>). Four electronic literature databases were searched to identify included studies: Cochrane, EMBASE, PubMed and Web of Science. Search terms included combinations of subject and free words for interventions, outcome indicators, and study subjects (see <xref ref-type="table" rid="tab1">Table 1</xref>).</p>
<table-wrap position="float" id="tab1">
<label>Table 1</label>
<caption>
<p>Systematic review search terms.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Interventions (linked by or)</th>
<th align="left" valign="top">Outcome indicators (linked by or)</th>
<th align="left" valign="top">Study subjects (linked by or)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">High intensity interval training<break/>High-intensity interval trainings<break/>Interval training, high-intensity<break/>Interval trainings, high-intensity<break/>Training, high-intensity interval<break/>Trainings, high-intensity interval<break/>High-intensity Intermittent exercise<break/>Exercise, high-intensity intermittent<break/>Exercises, high-intensity intermittent<break/>High-intensity Intermittent exercises<break/>Sprint interval training<break/>Sprint interval trainings</td>
<td align="left" valign="top">Affective<break/>Enjoyment<break/>Pleasure<break/>Mood<break/>Happiness</td>
<td align="left" valign="top">Overweight<break/>Obese</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>Interventions, outcome indicators and study subjects are linked by &#x2018;AND&#x2019;.</p>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="sec9">
<label>2.2</label>
<title>Eligibility criteria</title>
<p>The following inclusion criteria were used to select studies: (1) overweight or obese adults aged &#x2265;18&#x202F;years; (2) comparison of the HIIT with the MICT; (3) reported measures of affect, pleasure, and intention and (4) overweight or obese who participated in HIIT and MICT. All the studies are randomized controlled trials.</p>
</sec>
<sec id="sec10">
<label>2.3</label>
<title>Literature quality evaluation</title>
<p>In this study, 2 evaluators (YL and JSZ) independently assessed the quality of the included literature by using Cochrane Collaboration&#x2019;s tool for assessing risk of bias. The quality of the literature was systematically evaluated in the following 7 areas: (1) description of the randomization method; (2) concealment of the allocation scheme; (3) double-blind principle; (4) blinding principle for outcome evaluation; (5) data completeness; (6) selective reporting of outcome results; and (7) assessment of the presence of other biases (<xref ref-type="fig" rid="fig1">Figure 1</xref>).</p>
<fig position="float" id="fig1">
<label>Figure 1</label>
<caption>
<p>The bias risk assessment included in the literature. Green represents low risk and red represents high risk; yellow represents uncertainty.</p>
</caption>
<graphic xlink:href="fpubh-12-1487789-g001.tif"/>
</fig>
</sec>
<sec id="sec11">
<label>2.4</label>
<title>Data extraction</title>
<p>Data extraction and literature quality assessment were conducted independently by 2 evaluators (YL and JSZ) who extracted data from the included studies into an electronic data extraction form. When there is disagreement, a third reviewer will reevaluate it. Extracted data included literature general study information, study participant information (number, age, BMI), intervention characteristics (intensity, duration), and data on outcome indicators. When situations existed where data were unavailable, but graphical displays were available, we extracted data using a freely available web-based data extraction tool (Engauge Digitizer version 12.1) (<xref ref-type="bibr" rid="ref28">28</xref>&#x2013;<xref ref-type="bibr" rid="ref31">31</xref>).</p>
<p>Data extraction and literature quality assessment were compared between two evaluators, with any disagreements being resolved by a third evaluator.</p>
</sec>
<sec id="sec12">
<label>2.5</label>
<title>Publication bias</title>
<p>A visual analysis of funnel plot and the Egger&#x2019;s and Begg&#x2019;s test were performed to assess the publication bias across studies. At the same time, we used trim-and-fill process to assess the publication bias. This method involves examining the correlation between effect sizes and standard errors of effect sizes to determine if there is a significant association between study effect size and study precision.</p>
</sec>
<sec id="sec13">
<label>2.6</label>
<title>Statistical analysis</title>
<p>Effect sizes were determined by calculating the standardized mean difference (SMD). Heterogeneity was tested using <italic>I</italic><sup>2</sup>. <italic>I</italic><sup>2</sup> for 0&#x2013;50% is low heterogeneity and 50&#x2013;100% is high heterogeneity (<xref ref-type="bibr" rid="ref32">32</xref>). Due to the heterogeneity of the Meta-analysis, a random effects model was chosen to integrate the combined data across the text. Review Manager 5.4.1 was used to perform three statistical analyses with confidence intervals (CI) of 95% for the three outcomes (Physical Activity Enjoyment Scale, Feeling Scale and Felt Arousal Scale) of this study.</p>
</sec>
</sec>
<sec sec-type="results" id="sec14">
<label>3</label>
<title>Results</title>
<sec id="sec15">
<label>3.1</label>
<title>Literature screening results</title>
<p>The initial review yielded 73 studies, and after excluding 10 duplicates, 11 studies that were not relevant to the topic, 21 studies that did not compared HIIT and MICT, 5 review studies, 2studies that had the same data and could not be analyzed based on the titles and abstracts, 2 other language studies, 1 chronic study, 2paediatric studies and 3 other studies, there were still 16 studies that needed to be evaluated in full text. <xref ref-type="fig" rid="fig2">Figure 2</xref> illustrates the PRISMA process for study selection.</p>
<fig position="float" id="fig2">
<label>Figure 2</label>
<caption>
<p>The flow chart of literature inclusion screening.</p>
</caption>
<graphic xlink:href="fpubh-12-1487789-g002.tif"/>
</fig>
<p>A total of 537 participants met the inclusion criteria in 16 studies, including 213 participants in HIIT, 183 participants in MICT, 84 participants in alternating HIIT and MICT, and 57 participants in other forms of intervention (self-selected intensity exercise, very high-intensity interval exercise, repetitive sprint training, and blank control). All participants were between the ages of 18&#x2013;70&#x202F;years, had an intervention duration of 1&#x2013;16&#x202F;weeks, and had a BMI of 25 or higher. Five studies crossed over two exercises with the same group of participants. Eleven studies had participants under the age of 40&#x202F;years, three between the ages of 40&#x2013;60&#x202F;years, and two over the age of 60&#x202F;years.</p>
</sec>
<sec id="sec16">
<label>3.2</label>
<title>Quality evaluation included in the study</title>
<p>Nine studies described the use of randomized grouping methods, such as the random number table method or computer generated randomization (<xref ref-type="bibr" rid="ref21">21</xref>, <xref ref-type="bibr" rid="ref29">29</xref>, <xref ref-type="bibr" rid="ref31">31</xref>, <xref ref-type="bibr" rid="ref33">33</xref>&#x2013;<xref ref-type="bibr" rid="ref38">38</xref>), they were therefore assessed as having a low risk of bias. Seven studies were assessed as having an unclear risk of bias due to the lack of description of the randomization method (<xref ref-type="bibr" rid="ref28">28</xref>, <xref ref-type="bibr" rid="ref30">30</xref>, <xref ref-type="bibr" rid="ref39">39</xref>&#x2013;<xref ref-type="bibr" rid="ref43">43</xref>).</p>
<p>Seven studies described a method of allocation concealment in which sealed opaque envelopes were employed or allocated by a third people (<xref ref-type="bibr" rid="ref31">31</xref>, <xref ref-type="bibr" rid="ref33">33</xref>, <xref ref-type="bibr" rid="ref36">36</xref>&#x2013;<xref ref-type="bibr" rid="ref40">40</xref>), thus were assessed as having a low risk of bias. The remaining 10 studies did not describe the allocation hiding method, thus indicating an unclear risk of bias (<xref ref-type="bibr" rid="ref21">21</xref>, <xref ref-type="bibr" rid="ref28">28</xref>&#x2013;<xref ref-type="bibr" rid="ref30">30</xref>, <xref ref-type="bibr" rid="ref34">34</xref>, <xref ref-type="bibr" rid="ref35">35</xref>, <xref ref-type="bibr" rid="ref41">41</xref>&#x2013;<xref ref-type="bibr" rid="ref43">43</xref>).</p>
<p>One study showed that participants were not blinded (<xref ref-type="bibr" rid="ref21">21</xref>), it was therefore assessed as having a high risk of performance bias. Three studies have a low risk of bias due to the description of the double-blind method (<xref ref-type="bibr" rid="ref34">34</xref>, <xref ref-type="bibr" rid="ref40">40</xref>, <xref ref-type="bibr" rid="ref43">43</xref>). The rest 12 studies did not describe the use of blinding of participates and personnel (<xref ref-type="bibr" rid="ref28">28</xref>&#x2013;<xref ref-type="bibr" rid="ref31">31</xref>, <xref ref-type="bibr" rid="ref33">33</xref>, <xref ref-type="bibr" rid="ref35">35</xref>&#x2013;<xref ref-type="bibr" rid="ref39">39</xref>, <xref ref-type="bibr" rid="ref41">41</xref>, <xref ref-type="bibr" rid="ref42">42</xref>), thus indicating an unclear risk of bias.</p>
<p>In four studies, detection bias was judged to be low risk because they provided detailed information on the assessment of blinded outcomes (<xref ref-type="bibr" rid="ref21">21</xref>, <xref ref-type="bibr" rid="ref28">28</xref>, <xref ref-type="bibr" rid="ref35">35</xref>, <xref ref-type="bibr" rid="ref41">41</xref>). The other 12 studies were judged to have uncertain risk because there was no description of blind outcome assessment (<xref ref-type="bibr" rid="ref29">29</xref>&#x2013;<xref ref-type="bibr" rid="ref31">31</xref>, <xref ref-type="bibr" rid="ref33">33</xref>, <xref ref-type="bibr" rid="ref34">34</xref>, <xref ref-type="bibr" rid="ref36">36</xref>&#x2013;<xref ref-type="bibr" rid="ref40">40</xref>, <xref ref-type="bibr" rid="ref42">42</xref>, <xref ref-type="bibr" rid="ref43">43</xref>).</p>
<p>All 16 studies, reported complete outcome data, thus were assessed as having a low risk of bias.</p>
<p>Two studies did not report all pre-specified primary outcome (<xref ref-type="bibr" rid="ref30">30</xref>, <xref ref-type="bibr" rid="ref34">34</xref>), thus were judged to be high reporting risk. Two studies had insufficient information to determine whether there was a risk of selective reporting of results (<xref ref-type="bibr" rid="ref39">39</xref>, <xref ref-type="bibr" rid="ref41">41</xref>), thus were judged to be unclear reporting risk bias. The other 12 studies were judged to have low risk because all needed outcomes have been reported (<xref ref-type="bibr" rid="ref21">21</xref>, <xref ref-type="bibr" rid="ref28">28</xref>, <xref ref-type="bibr" rid="ref29">29</xref>, <xref ref-type="bibr" rid="ref31">31</xref>, <xref ref-type="bibr" rid="ref33">33</xref>, <xref ref-type="bibr" rid="ref35">35</xref>&#x2013;<xref ref-type="bibr" rid="ref38">38</xref>, <xref ref-type="bibr" rid="ref40">40</xref>, <xref ref-type="bibr" rid="ref42">42</xref>, <xref ref-type="bibr" rid="ref43">43</xref>).</p>
</sec>
<sec id="sec17">
<label>3.3</label>
<title>Publication bias and sensitivity analysis</title>
<p>Meta-analysis showed high heterogeneity of PACES and FS, and exclusion of the studies failed to reduce the level of heterogeneity, indicating a stable overall outcome. However, after excluding two studies (<xref ref-type="bibr" rid="ref31">31</xref>, <xref ref-type="bibr" rid="ref34">34</xref>) the heterogeneity of PACES was significantly reduced to a relatively low level (<italic>I</italic><sup>2</sup>&#x202F;=&#x202F;46%). All two studies had an intervention duration of 12&#x202F;weeks, three times per week, to further investigate the possibility of high heterogeneity, we performed subgroup analyses for age, form of exercise, and duration of exercise, but the significance of the results did not change significantly.</p>
<p>We used funnel plot and trim and fill process to assess publication bias. Based on visual observations, we found that the funnel plot for PACES and FS, there is no significant asymmetry (<xref ref-type="fig" rid="fig3">Figures 3</xref>, <xref ref-type="fig" rid="fig4">4</xref>), which suggests that the included studies may not be significantly affected by publication bias, so the results of the meta-analysis may be relatively reliable. Further quantitative tests showed that there was no significant publication bias across studies (Begg&#x2019;s test, <italic>p</italic> =&#x202F;0.100; Egger&#x2019;s test, <italic>p</italic>&#x202F;=&#x202F;0.152, <xref rid="SM1" ref-type="supplementary-material">Supplementary Figure 1</xref>; The estimated effect size is 1.160 with a 95% confidence interval of 0.147 to 2.173, <xref rid="SM1" ref-type="supplementary-material">Supplementary Figure 2</xref>. Begg&#x2019;s test, <italic>p</italic> =&#x202F;0.368; Egger&#x2019;s test, <italic>p</italic> =&#x202F;0.867, <xref rid="SM1" ref-type="supplementary-material">Supplementary Figure 3</xref>; The estimated effect size is &#x2212;1.362 with a 95% confidence interval of &#x2212;3.787 to 1.063, <xref rid="SM1" ref-type="supplementary-material">Supplementary Figure 4</xref>). The analysis revealed no studies to be supplemented, indicating that there was no significant publication bias in the current dataset, or that the effect of publication bias was not large enough to be corrected by trim and fill process.</p>
<fig position="float" id="fig3">
<label>Figure 3</label>
<caption>
<p>Funnel plot for PACES meta-analysis.</p>
</caption>
<graphic xlink:href="fpubh-12-1487789-g003.tif"/>
</fig>
<fig position="float" id="fig4">
<label>Figure 4</label>
<caption>
<p>Funnel plot for FS meta-analysis.</p>
</caption>
<graphic xlink:href="fpubh-12-1487789-g004.tif"/>
</fig>
</sec>
<sec id="sec18">
<label>3.4</label>
<title>Meta-analysis</title>
<p>Study characteristics are summarized in <xref ref-type="table" rid="tab2">Table 2</xref>.</p>
<table-wrap position="float" id="tab2">
<label>Table 2</label>
<caption>
<p>Enjoyment and affective data of the selected studies.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top" rowspan="2">Inclusion research</th>
<th align="center" valign="top" rowspan="2">Country</th>
<th align="left" valign="top" colspan="2">Participant information</th>
<th align="left" valign="top" rowspan="2">Intervention time</th>
<th align="left" valign="top" colspan="2">Exercise conditions</th>
<th align="center" valign="top" colspan="2">PACES scores</th>
<th align="center" valign="top" colspan="2">FS scores</th>
</tr>
<tr>
<th align="left" valign="top">HIIT</th>
<th align="left" valign="top">MICT</th>
<th align="left" valign="top">HIIT</th>
<th align="left" valign="top">MICT</th>
<th align="center" valign="top">HIIT</th>
<th align="center" valign="top">MICT</th>
<th align="center" valign="top">HIIT</th>
<th align="center" valign="top">MICT</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="middle">Farias-Junior et al. (<xref ref-type="bibr" rid="ref39">39</xref>)</td>
<td align="left" valign="middle">Brazil</td>
<td align="left" valign="middle">Number:20<break/>Age: 28.9 (5.0)<break/>BMI: 28.9 (4.98)</td>
<td align="left" valign="middle">Number:20<break/>Age: 28.9 (5.0)<break/>BMI: 28.9 (4.98)</td>
<td align="left" valign="middle">once</td>
<td align="left" valign="middle">10&#x002A; 1&#x202F;min high-intensity-exercise at 75&#x2013;80% HRR, interspersed with 10&#x002A; 1&#x202F;min rest at 35&#x2013;40% HRR</td>
<td align="left" valign="middle">20&#x202F;min of continuous exercise at 55&#x2013;59% HRR</td>
<td align="center" valign="middle">106 (16.5)</td>
<td align="center" valign="middle">96 (14.5)</td>
<td align="center" valign="middle">&#x2212;3.1 (1.8)</td>
<td align="center" valign="middle">0.8 (1.8)</td>
</tr>
<tr>
<td align="left" valign="middle">Santos et al. (<xref ref-type="bibr" rid="ref36">36</xref>)</td>
<td align="left" valign="middle">Canada</td>
<td align="left" valign="middle">Number:47<break/>Age:<break/>51.8 (8.80)<break/>BMI: 31.4 (6.6)</td>
<td align="left" valign="middle">Number:52<break/>Age: 50.0 (9.90)<break/>BMI: 31.4 (5.9)</td>
<td align="left" valign="middle">2&#x202F;weeks</td>
<td align="left" valign="middle">4&#x2013;10 &#x002A;1&#x202F;min at ~77&#x2013;95% of max heart rate interspersed with 1&#x202F;min at 60% of HRmax</td>
<td align="left" valign="middle">20 to 50&#x202F;min exercise at 64&#x2013;76% of HRmax</td>
<td align="center" valign="middle">102.52 (17.5)</td>
<td align="center" valign="middle">101.53 (20.3)</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
</tr>
<tr>
<td align="left" valign="middle">Patten et al. (<xref ref-type="bibr" rid="ref34">34</xref>)</td>
<td align="left" valign="middle">Australia</td>
<td align="left" valign="middle">Number:15<break/>Age: 29.7 (4.8)<break/>BMI: 35.5 (6.8)</td>
<td align="left" valign="middle">Number:14<break/>Age: 32.5 (6.2)<break/>BMI: 38.4 (9.3)</td>
<td align="left" valign="middle">12&#x202F;weeks</td>
<td align="left" valign="middle">2&#x002A;(12 &#x002A; 1 min interval sat 90&#x2013;100% %HR peak, interspersed with 1&#x202F;min of active recovery)&#x202F;+&#x202F;1&#x002A;(8 &#x002A; 4&#x202F;min intervals at 90&#x2013;95%HRpeak, interspersed with a 2&#x202F;min light load)</td>
<td align="left" valign="middle">45&#x202F;min of continuous moderate-intensity cycling at 60&#x2013;75%HRpeak.</td>
<td align="center" valign="middle">101.8 (7.6)</td>
<td align="center" valign="middle">87.9 (7.6)</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
</tr>
<tr>
<td align="left" valign="middle">Poon et al. (<xref ref-type="bibr" rid="ref33">33</xref>)</td>
<td align="left" valign="middle">Canada</td>
<td align="left" valign="middle">Number:12<break/>Age: 49.6 (7.8)<break/>BMI: 26.1 (1.6)</td>
<td align="left" valign="middle">Number:<break/>12<break/>Age: 46.5 (3.6)<break/>BMI: 25.6 (3.1)</td>
<td align="left" valign="middle">8&#x202F;weeks</td>
<td align="left" valign="middle">10 &#x002A; 1&#x202F;min bouts of running at 80&#x2013;90% HRmax interspersed with 1&#x202F;min active recovery</td>
<td align="left" valign="middle">50&#x202F;min continuous jogging/brisk walking at 65&#x2013;70% HRmax</td>
<td align="center" valign="middle">111.4 (9.4)</td>
<td align="center" valign="middle">105.7 (14.7)</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
</tr>
<tr>
<td align="left" valign="middle" rowspan="2">Dupuit et al. (<xref ref-type="bibr" rid="ref37">37</xref>)</td>
<td align="left" valign="middle" rowspan="2">France</td>
<td align="left" valign="middle">HIIT 1 Number:12<break/>Age: 59.5 (5.8)<break/>BMI: 28.9 (3.9)</td>
<td align="left" valign="middle" rowspan="2">Number:12<break/>Age: 59.5 (5.8)<break/>BMI: 28.9 (3.9)</td>
<td align="left" valign="middle">once</td>
<td align="left" valign="middle">60&#x202F;cycles of sprinting/speeding for 8&#x202F;s interspersed with slow pedaling (20&#x2013;30&#x202F;rpm) for 12&#x202F;s</td>
<td align="left" valign="middle" rowspan="2">cycling for 35&#x202F;min at 60&#x2013;65% HRmax</td>
<td align="center" valign="middle">90.8 (17)</td>
<td align="center" valign="middle" rowspan="2">91.3 (15.4)</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
</tr>
<tr>
<td align="left" valign="middle">HIIT 2 Number:<break/>12<break/>Age: 59.5 (5.8)<break/>BMI: 28.9 (3.9)</td>
<td align="left" valign="middle">once</td>
<td align="left" valign="middle">10&#x002A;1&#x202F;min bouts at 80&#x2013;90% HRmax, interspersed with 10&#x002A;1&#x202F;min recovery bouts (ie, slow pedaling at 20&#x2013;30&#x202F;rpm).</td>
<td align="center" valign="middle">86.8 (10.9)</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
</tr>
<tr>
<td align="left" valign="middle">Vella et al. (<xref ref-type="bibr" rid="ref28">28</xref>)</td>
<td align="left" valign="middle">America</td>
<td align="left" valign="middle">Number:8<break/>Age: 23.1 (6.6)<break/>BMI: 29.9 (3.3)</td>
<td align="left" valign="middle">Number:9<break/>Age: 28.9 (8.1)<break/>BMI: 33.1 (6.0)</td>
<td align="left" valign="middle">5&#x202F;weeks</td>
<td align="left" valign="middle">10&#x002A;1&#x202F;min bouts of high-intensity exercise at 75&#x2013;80% HRR, interspersed with 10&#x002A;1&#x202F;min recovery bouts at 35&#x2013;40% HRR.</td>
<td align="left" valign="middle">20&#x202F;min of continuous exercise at 55&#x2013;59% HRR</td>
<td align="left" valign="middle">100.1 (4.3)</td>
<td align="left" valign="middle">100.3 (4.4)</td>
<td align="left" valign="middle"><italic>NM</italic></td>
<td align="left" valign="middle"><italic>NM</italic></td>
</tr>
<tr>
<td align="left" valign="middle">Poon et al. (<xref ref-type="bibr" rid="ref38">38</xref>)</td>
<td align="left" valign="middle">France</td>
<td align="left" valign="middle">Number:11<break/>Age: 40.5 (7.1)<break/>BMI: 26.3 (2.4)</td>
<td align="left" valign="middle">Number:10<break/>Age: 40.1 (3.6)<break/>BMI: 26.7 (2.6)</td>
<td align="left" valign="middle">16&#x202F;weeks</td>
<td align="left" valign="middle">12&#x002A;1&#x202F;min running bouts at 80e90% HRmax interspersed with 1&#x202F;min active recovery at 50% HRmax</td>
<td align="left" valign="middle">40&#x202F;min brisk walk at 65e70% HRmax</td>
<td align="center" valign="middle">109.1 (11.1)</td>
<td align="center" valign="middle">109.1 (9.5)</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
</tr>
<tr>
<td align="left" valign="middle" rowspan="2">Hu et al. (<xref ref-type="bibr" rid="ref31">31</xref>)</td>
<td align="left" valign="middle" rowspan="2">China</td>
<td align="left" valign="middle">HIIT Number:15<break/>Age: 21.5 (1.7)<break/>BMI: 25.5 (2.4)</td>
<td align="left" valign="middle" rowspan="2">Number:15<break/>Age: 20.9 (1.4)<break/>BMI: 25.8 (2.6)</td>
<td align="left" valign="middle">12&#x202F;weeks</td>
<td align="left" valign="middle">4&#x202F;min cycling bouts at 90% VO<sub>2</sub>peak and interspersed with 3&#x202F;min passive recovery bouts until the targeted mechanical work was achieved.</td>
<td align="left" valign="middle" rowspan="2">continuous cycling at a workload of 60% VO<sub>2</sub>peak until the targeted mechanical work was fulfilled.</td>
<td align="center" valign="middle">99.99 (4.78)</td>
<td align="center" valign="middle" rowspan="2">95.88 (1.4)</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
</tr>
<tr>
<td align="left" valign="middle">SSIT Number:15<break/>Age: 21.4 (1.0)<break/>BMI: 25.6 (2.3)</td>
<td align="left" valign="middle">12&#x202F;weeks</td>
<td align="left" valign="middle">80 repetitions of 6&#x202F;s cycling sprints interspersed with 9&#x202F;s passive recoveries (20&#x202F;min/session).</td>
<td align="center" valign="middle">101.79 (5.73)</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
</tr>
<tr>
<td align="left" valign="middle">Sim et al. (<xref ref-type="bibr" rid="ref41">41</xref>)</td>
<td align="left" valign="middle">Australia</td>
<td align="left" valign="middle">Number:17<break/>Age: 30 (8)<break/>BMI: 27.7 (1.6)</td>
<td align="left" valign="middle">Number:17<break/>Age: 30 (8)<break/>BMI: 27.7 (1.6)</td>
<td align="left" valign="middle">once</td>
<td align="left" valign="middle">1:4 (60s at 100% VO<sub>2</sub>peak: 240&#x202F;s at 50% VO<sub>2</sub>peak)</td>
<td align="left" valign="middle">30&#x202F;min continuous exercise performed at moderate intensity (60% VO<sub>2</sub>peak)</td>
<td align="center" valign="middle">86 (11)</td>
<td align="center" valign="middle">85 (13)</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
</tr>
<tr>
<td align="left" valign="middle" rowspan="2">Li et al. (<xref ref-type="bibr" rid="ref30">30</xref>)</td>
<td align="left" valign="middle" rowspan="2">China</td>
<td align="left" valign="middle">HIIT120 Number:14<break/>Age: 19.9 (1.7)<break/>BMI: &#x003E; 23</td>
<td align="left" valign="middle" rowspan="2">Number:14<break/>Age: 19.7 (1.0)<break/>BMI: &#x003E; 23</td>
<td align="left" valign="middle">12&#x202F;weeks</td>
<td align="left" valign="middle">1&#x202F;min effort at 120% VO<sub>2</sub>peak for 19&#x202F;&#x00B1;&#x202F;2&#x202F;min</td>
<td align="left" valign="middle" rowspan="2">60% VO<sub>2</sub>peak for 57&#x202F;&#x00B1;&#x202F;8&#x202F;min</td>
<td align="center" valign="middle">92.5 (11.4)</td>
<td align="center" valign="middle" rowspan="2">80.8 (11.8)</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
</tr>
<tr>
<td align="left" valign="middle">HIIT90 Number:14<break/>Age: 20.7 (2.2)<break/>BMI: &#x003E; 23</td>
<td align="left" valign="middle">12&#x202F;weeks</td>
<td align="left" valign="middle">4&#x202F;min effort at 90% VO<sub>2</sub>peak for 26&#x202F;&#x00B1;&#x202F;3&#x202F;min</td>
<td align="center" valign="middle">96.8 (13.9)</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
</tr>
<tr>
<td align="left" valign="middle">Decker &#x0026; Ekkekakis (<xref ref-type="bibr" rid="ref35">35</xref>)</td>
<td align="left" valign="middle">America</td>
<td align="left" valign="middle">Number:24<break/>Age: 39.25 (11.23)<break/>BMI: 34.96 (4.46)</td>
<td align="left" valign="middle">Number:24<break/>Age: 39.25 (11.23)<break/>BMI: 34.96 (4.46)</td>
<td align="left" valign="middle">once</td>
<td align="left" valign="middle">4&#x002A; 3&#x202F;min intervals of recumbent cycling at 115% of Watts</td>
<td align="left" valign="middle">25&#x202F;min of recumbent cycling at 90% of Watts</td>
<td align="center" valign="middle">82.25 (21.76)</td>
<td align="center" valign="middle">90.79 (22.6)</td>
<td align="center" valign="middle">1.25 (1.47)</td>
<td align="center" valign="middle">2 (1.22)</td>
</tr>
<tr>
<td align="left" valign="middle">Oliveira, et al. (<xref ref-type="bibr" rid="ref29">29</xref>)</td>
<td align="left" valign="middle">Brazil</td>
<td align="left" valign="middle">Number:12<break/>Age: 27.92 (7.98)<break/>BMI: 28.65 (3.85)</td>
<td align="left" valign="middle">Number:13<break/>Age: 32.46 (7.60)<break/>BMI: 27.90 (3.90)</td>
<td align="left" valign="middle">12&#x202F;weeks</td>
<td align="left" valign="middle">10 &#x002A;1&#x202F;min high-intensity bouts (brisk walking or jogging or running) at RPE 15&#x2013;17 (i.e., &#x201C;hard to very hard&#x201D;) interspersed with 1&#x202F;min of active recovery walking slowly (20 min exercise).</td>
<td align="left" valign="middle">30&#x202F;min at PRE13</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle">0.51 (0.55)</td>
<td align="center" valign="middle">1.31 (0.53)</td>
</tr>
<tr>
<td align="left" valign="middle">Marillier et al. (<xref ref-type="bibr" rid="ref22">22</xref>)</td>
<td align="left" valign="middle">France</td>
<td align="left" valign="middle">Number:10<break/>Age: 48.5 (7.6)<break/>BMI: 31.9 (5.7)</td>
<td align="left" valign="middle">Number:10<break/>Age: 47.8 (9.7)<break/>BMI: 33.5 (11.4)</td>
<td align="left" valign="middle">8&#x202F;weeks</td>
<td align="left" valign="middle">1&#x202F;min bouts of cycling at 100% WR peak interspaced by 1&#x202F;min of passive recovery.</td>
<td align="left" valign="middle">50% peak work rate (WR peak) for 45&#x202F;min</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle">3.22 (1.09)</td>
<td align="center" valign="middle">3.06 (2.05)</td>
</tr>
<tr>
<td align="left" valign="middle">Ram et al. (<xref ref-type="bibr" rid="ref21">21</xref>)</td>
<td align="left" valign="middle">Australia</td>
<td align="left" valign="middle">Number:16<break/>Age: 30 (6)<break/>BMI: 28.1 (4.1)</td>
<td align="left" valign="middle">Number:12<break/>Age: 20 (8)<break/>BMI: 27.4 (4.0)</td>
<td align="left" valign="middle">6&#x202F;weeks</td>
<td align="left" valign="middle">10&#x202F;&#x00D7;&#x202F;1&#x202F;min intervals at ~90% HRpeak interspersed with 1&#x202F;min active recovery intervals at a low workload (15%WRpeak)</td>
<td align="left" valign="middle">30&#x202F;min at 65&#x2013;75% HRpeak</td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle"><italic>NM</italic></td>
<td align="center" valign="middle">2.69 (0.9)</td>
<td align="center" valign="middle">2.09 (1.1)</td>
</tr>
<tr>
<td align="left" valign="middle">Boukabous et al. (<xref ref-type="bibr" rid="ref42">42</xref>)</td>
<td align="left" valign="middle">Canada</td>
<td align="left" valign="middle">Number:9<break/>Age: 66.0 (3.4)<break/>BMI: 30.1 (4.9)</td>
<td align="left" valign="middle">Number:9<break/>Age: 64.2 (3.7)<break/>BMI: 31.7 (3.5)</td>
<td align="left" valign="middle">8&#x202F;weeks</td>
<td align="left" valign="middle">6&#x002A; 1&#x202F;min intervals at 90% HRR interspersed by 2&#x202F;min of active recovery at 40% HRR, and a 2&#x202F;min cool down at 40% HRR</td>
<td align="left" valign="middle">45&#x202F;min of exercise at 55% HRR</td>
<td align="left" valign="middle"><italic>NM</italic></td>
<td align="left" valign="middle"><italic>NM</italic></td>
<td align="left" valign="middle">4.2 (0.9)</td>
<td align="left" valign="middle">4.1 (0.9)</td>
</tr>
<tr>
<td align="left" valign="middle">Kong et al. (<xref ref-type="bibr" rid="ref43">43</xref>)</td>
<td align="left" valign="middle">China</td>
<td align="left" valign="middle">Number:15<break/>Age: 20.8 (2.7)<break/>BMI: 25.5 (3.1)</td>
<td align="left" valign="middle">Number:13<break/>Age: 21.5 (3.1)<break/>BMI: 24.9 (1.9)</td>
<td align="left" valign="middle">4&#x202F;weeks</td>
<td align="left" valign="middle">10 sets of 6&#x202F;s all-out cycling interspersed with 9&#x202F;s of rest</td>
<td align="left" valign="middle">30&#x202F;min cycling at 50&#x2013;60% of peak oxygen consumption, VO<sub>2</sub>peak</td>
<td align="left" valign="middle"><italic>NM</italic></td>
<td align="left" valign="middle"><italic>NM</italic></td>
<td align="left" valign="middle">1.33 (1.57)</td>
<td align="left" valign="middle">1.28 (1.57)</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>HRR, heart rate reserve; HRpeak, peak heart rate; HRmax, maximal heart rate; VO<sub>2</sub>max, maximal oxygen uptake; VO<sub>2</sub>peak, peak oxygen consumption; WRpeak, peak work rate; RPE, Rating of perceived exertion; NM, Not measured. Data are expressed as mean (SD).</p>
</table-wrap-foot>
</table-wrap>
<sec id="sec19">
<label>3.4.1</label>
<title>Enjoyment response analysis</title>
<p>A total of 11 studies have measured the enjoyment response to HIIT and MICT (<xref ref-type="table" rid="tab2">Table 2</xref>) in a manner that was measured using the Physical Activity Enjoyment Scale (PACES; (<xref ref-type="bibr" rid="ref44">44</xref>)) at the end of training. Two of the studies were measured once after 8 and 16&#x202F;weeks of training, so these two studies were chronic studies (<xref ref-type="bibr" rid="ref33">33</xref>, <xref ref-type="bibr" rid="ref38">38</xref>) and the rest were acute studies. A high level of heterogeneity was observed in the combined results (<italic>I</italic><sup>2</sup>&#x202F;=&#x202F;69%), so a random-effects model was used. Meta-analysis showed that the overall effect of the pleasure response (SMD&#x202F;=&#x202F;0.47; 95% CI&#x202F;=&#x202F;0.12&#x202F;~&#x202F;081; <italic>p</italic>&#x202F;&#x003C;&#x202F;0.05) was statistically significant, indicating that the difference in the rate of outcome events between the two groups was statistically significant (<xref ref-type="fig" rid="fig5">Figure 5</xref>).</p>
<fig position="float" id="fig5">
<label>Figure 5</label>
<caption>
<p>Standardized mean difference of physical activity enjoyment scale between HIIT and MICT conditions. CI, confidence interval; HIIT, high intensity interval training; MICT, moderate intensity continuous training.</p>
</caption>
<graphic xlink:href="fpubh-12-1487789-g005.tif"/>
</fig>
<p>However, it is still difficult to evaluate what the clinical consequences of this heterogeneity may be for future settings. So a prediction interval is reported in the study to illustrate which range of true effects can be expected in future settings. The resulting SD<sub>PI</sub> =&#x202F;0.566, 95% prediction interval ranging from &#x2212;0.758 to 1.688. This suggests that the true effect size in similar future studies may be in this range, or may even be opposite to summary point estimate of the meta-analysis, or have greater effect uncertainty (<xref ref-type="bibr" rid="ref45">45</xref>).</p>
<sec id="sec20">
<label>3.4.1.1</label>
<title>Subgroup analysis of acute and chronic studies</title>
<p>A subgroup analysis was performed to investigate the difference between acute and chronic studies. As shown in <xref ref-type="fig" rid="fig6">Figure 6</xref>, nine acute studies (SMD&#x202F;=&#x202F;0.51; 95% CI&#x202F;=&#x202F;0.12 to 0.90; <italic>p</italic>&#x202F;&#x003C;&#x202F;0.05) showed beneficial overall effects of HIIT on enjoyment, indicating that HIIT exercise may contribute to obtaining psychological responses that are equal to or more positive than MICT sessions in short period. In contrast, two chronic studies (SMD =0.23; 95% CI&#x202F;=&#x202F;&#x2212;0.35 to 0.82; <italic>p</italic>&#x202F;&#x003E;&#x202F;0.05) did not show a significant effect.</p>
<fig position="float" id="fig6">
<label>Figure 6</label>
<caption>
<p>Results of subgroup analysis of acute and chronic studies; CI, confidence interval; HIIT, high intensity interval training; MICT, moderate intensity continuous training.</p>
</caption>
<graphic xlink:href="fpubh-12-1487789-g006.tif"/>
</fig>
</sec>
</sec>
<sec id="sec21">
<label>3.4.2</label>
<title>Affective response analysis</title>
<p>A total of seven studies have measured affective responses to HIIT and MICT using the Feeling Scale (FS; (<xref ref-type="bibr" rid="ref46">46</xref>)) before, during and after exercise (<xref ref-type="table" rid="tab3">Table 3</xref>), all of them are acute studies. For studies where multiple measures of affective responses (pre-, mid-, and post-exercise) were present, we calculated mean and standard deviation values, reducing the data for each exercise condition to only one value. A high level of heterogeneity was observed in the combined outcome Feeling Scale (<italic>I</italic><sup>2</sup>&#x202F;=&#x202F;82%), so a random-effects model was used. Meta-analysis showed that the overall effect of Feeling Scale (SMD&#x202F;=&#x202F;&#x2212;0.47; 95% CI&#x202F;=&#x202F;&#x2212;1.17&#x202F;~&#x202F;0.23; <italic>p</italic>&#x202F;&#x003E;&#x202F;0.05) was not statistically significant, indicating that the difference in the rates of outcome events between the two groups was not statistically significant (<xref ref-type="fig" rid="fig7">Figure 7</xref>). The resulting SD<sub>PI</sub> =&#x202F;0.920, 95% prediction interval ranging from &#x2212;2.721 to 1.781. This suggests that although the current effect estimates are negative, near zero or slightly positive effects may be expected in future studies.</p>
<table-wrap position="float" id="tab3">
<label>Table 3</label>
<caption>
<p>Arousal data of the selected studies.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top" rowspan="2">Inclusion research</th>
<th align="left" valign="top" rowspan="2">Country</th>
<th align="left" valign="top" colspan="2">Participant information</th>
<th align="left" valign="top" colspan="2">Exercise conditions</th>
<th align="center" valign="top" colspan="2">Scores</th>
</tr>
<tr>
<th align="left" valign="top">HIIT</th>
<th align="left" valign="top">MICT</th>
<th align="left" valign="top">HIIT</th>
<th align="left" valign="top">MICT</th>
<th align="center" valign="top">HIIT</th>
<th align="center" valign="top">MICT</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="middle">Marillier et al. (<xref ref-type="bibr" rid="ref22">22</xref>)</td>
<td align="left" valign="middle">France</td>
<td align="left" valign="middle">Number:10<break/>Age: 48.5 (7.6)<break/>BMI: 31.9 (5.7)</td>
<td align="left" valign="middle">Number:10<break/>Age: 47.8 (9.7)<break/>BMI: 33.5 (11.4)</td>
<td align="left" valign="middle">1 min bouts of cycling at 100% WRpeak interspaced by 1&#x202F;min of passive recovery.</td>
<td align="left" valign="middle">50% peak work rate (WRpeak) for 45&#x202F;min</td>
<td align="center" valign="middle">3.1 (1.53)</td>
<td align="center" valign="middle">3.48 (1.13)</td>
</tr>
<tr>
<td align="left" valign="middle">Kong et al. (<xref ref-type="bibr" rid="ref43">43</xref>)</td>
<td align="left" valign="middle">China</td>
<td align="left" valign="middle">Number:15<break/>Age: 20.8 (2.7)<break/>BMI: 25.5 (3.1)</td>
<td align="left" valign="middle">Number:13<break/>Age: 21.5 (3.1)<break/>BMI: 24.9 (1.9)</td>
<td align="left" valign="middle">10 sets of 6&#x202F;s all-out cycling interspersed with 9&#x202F;s of rest</td>
<td align="left" valign="middle">30&#x202F;min cycling at 50&#x2013;60% of peak oxygen consumption, VO<sub>2</sub>peak</td>
<td align="center" valign="middle">3.83 (0.96)</td>
<td align="center" valign="middle">4.1 (0.78)</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>WRpeak, peak work rate; VO<sub>2</sub>peak, peak oxygen consumption. Data are expressed as mean (SD).</p>
</table-wrap-foot>
</table-wrap>
<fig position="float" id="fig7">
<label>Figure 7</label>
<caption>
<p>Standardized mean difference of Feeling Scale between HIIT and MICT conditions. CI, confidence interval; HIIT, high intensity interval training; MICT, moderate intensity continuous training.</p>
</caption>
<graphic xlink:href="fpubh-12-1487789-g007.tif"/>
</fig>
</sec>
<sec id="sec22">
<label>3.4.3</label>
<title>Arousal analysis</title>
<p>Two of these studies also used the Felt Arousal Scale (<xref ref-type="bibr" rid="ref47">47</xref>) measured before and after exercise (<xref ref-type="table" rid="tab3">Table 3</xref>). A low level of heterogeneity was observed in the combined outcome Felt Arousal Scale (<italic>I</italic><sup>2</sup>&#x202F;=&#x202F;0%), and therefore a fixed-effects model was used. Meta-analysis showed that the overall effect of Felt Arousal Scale (SMD&#x202F;=&#x202F;&#x2212;0.29; 95% CI&#x202F;=&#x202F;&#x2212;0.86&#x202F;~&#x202F;0.28; <italic>p</italic>&#x202F;&#x003E;&#x202F;0.05) was not statistically significant, indicating that the difference in the rate of outcome events between the two groups was not statistically significant (<xref ref-type="fig" rid="fig8">Figure 8</xref>).</p>
<fig position="float" id="fig8">
<label>Figure 8</label>
<caption>
<p>Standardized mean difference of Felt Arousal Scale between HIIT and MICT conditions. CI, confidence interval; HIIT, high intensity interval training; MICT, moderate intensity continuous training.</p>
</caption>
<graphic xlink:href="fpubh-12-1487789-g008.tif"/>
</fig>
</sec>
</sec>
</sec>
<sec sec-type="discussion" id="sec23">
<label>4</label>
<title>Discussion</title>
<p>The objective of this meta-analysis is to evaluate and compare the effectiveness of HIIT and MICT on enjoyment and affective responses in overweight or obese people, and to explore the most appropriate exercise mode for overweight or obese people.</p>
<sec id="sec24">
<label>4.1</label>
<title>Enjoyment response of HIIT compared with MICT</title>
<p>While affect is a conscious response to an emotional direction (positive, neutral, or negative), enjoyment is a more specific feeling (<xref ref-type="bibr" rid="ref48">48</xref>). Traditional concept suggests that high-intensity exercise above the ventilation threshold can cause unpleasant feelings about exercise (<xref ref-type="bibr" rid="ref49">49</xref>). Although HIIT is a form of high-intensity exercise, it is characterized by brief, repeated intervals of rest or low-intensity exercise (<xref ref-type="bibr" rid="ref50">50</xref>). There are multiple &#x201C;recovery&#x201D; cycles, which can lead to a psychological &#x201C;rebound effect&#x201D; in exercisers. Jung suggests that during recovery intervals there may be a &#x201C;rebound effect&#x201D; whereby participants may feel a more positive emotional response during the recovery period, as the intervals may contribute to a repeated boost in confidence during a single workout, allowing participants to know that they are approaching a &#x201C;comfort zone&#x201D; for recovery, and thus mobilizing their own positive emotions (<xref ref-type="bibr" rid="ref51">51</xref>), Participants&#x2019; confidence and mobilization of positive emotions can thus be continuously enhanced. However, the &#x201C;rebound effect&#x201D; seems to occur only on the post-exercise scale, because participants have more time to cushion and recover after exercise, and the use of the scale during exercise may not be a good explanation for this effect, because participants will still feel tired during short intervals of exercise. Therefore, the overall effect of HIIT on the PACES scale measured after exercise will be better than MICT.</p>
<p>In addition, exercise preference is one of the factors that influence people&#x2019;s choice of different types of exercise. Hedonistic theories of behavior suggest that people are intrinsically predisposed to behaviors that bring them pleasure and stay away from those that bring them displeasure (<xref ref-type="bibr" rid="ref52">52</xref>). It has been suggested that HIIT may be preferred for achieving personal health goals better than MICT, which may cause participants to become frustrated and give up more easily because it may take more time (<xref ref-type="bibr" rid="ref53">53</xref>).</p>
<p>It is worth noting that it involves both acute and chronic studies on enjoyment response. The result of subgroup analysis of acute and chronic studies shows that HIIT may contribute to obtaining psychological responses that are equal to or more positive than MICT in short period. The reason why it is feasible to include both acute and chronic is because we are looking at an overall effect. Acute effects may disappear over time, or adaptive changes may occur over a long period of time. By combining acute and chronic studies, we can reveal more complex time-dependent effects. The overall effect shows beneficial effects of HIIT on enjoyment indicating that overweight or obese people may more willing to try HIIT due to hedonistic theories of behavior.</p>
</sec>
<sec id="sec25">
<label>4.2</label>
<title>Affective response of HIIT compared with MICT</title>
<p>Results show that the difference in the rates of outcome events between the two groups was not statistically significant. It might because HIIT is performed using multiple sets of stimulus/recovery combinations, and variations in the ratio of stimulus to recovery time will affect the emotional experience of participants, which will likely have an impact on affective responses (<xref ref-type="bibr" rid="ref43">43</xref>). In the experimental design of Oliveira et al. (<xref ref-type="bibr" rid="ref29">29</xref>), the affective responses to HIIT were lower than those of MICT in a pattern of 1&#x202F;min of exercise with 1&#x202F;min of active recovery as a group (<xref ref-type="bibr" rid="ref29">29</xref>). However, in the experimental design of Ram et al. the affective responses to HIIT were higher than those of MICT in a pattern of 10 &#x002A; 1&#x202F;min intervals at 90% peak heart rate with 1&#x202F;min active recovery intervals at a low workload (15% WRpeak) (<xref ref-type="bibr" rid="ref21">21</xref>), suggesting that by rationalizing the ratio of stimulation to recovery time in high-intensity exercise and improving the affective responses resulting from influencing it, it might be a good prescription for the overweight and obese groups.</p>
</sec>
<sec id="sec26">
<label>4.3</label>
<title>Arousal of HIIT compared with MICT</title>
<p>Two studies reported data on the assessment of Arousal during exercise using Felt Arousal Scale (<xref ref-type="bibr" rid="ref47">47</xref>). Due to the small number of literatures and the different measurement times of FAS scale in the two studies, the average score was calculated for analysis. The results showed that both HIIT and MICT could bring positive emotional activation responses to participants, but there was no significant difference between groups (SMD&#x202F;=&#x202F;&#x2212;0.29; 95% CI&#x202F;=&#x202F;&#x2212;0.86&#x202F;~&#x202F;0.28; <italic>p</italic> &#x003E;&#x202F;0.05). Due to the limited amount of literature, it may not be possible to fully understand the research status and development trend of this field. In addition, the lack of sufficient information may also limit the in-depth discussion of certain specific issues. However, studies have shown that emotional activation depends on the intensity of the activity (e.g., light or moderate intensity) or the different moments of the session (e.g., warm up, cool down) (<xref ref-type="bibr" rid="ref54">54</xref>). Thus, the results should be treated with caution.</p>
<p>In conclusion, this review showed that HIIT can bring better pleasure response than MICT in overweight or obese people, but there is no significant difference in emotional response. It is possible that the inconsistency between this conclusion and the results of existing studies may also be due to differences in the interventions, such as the relative intensity, duration, and total number of work sessions completed (<xref ref-type="bibr" rid="ref34">34</xref>, <xref ref-type="bibr" rid="ref39">39</xref>); and heterogeneity in the backgrounds of the participants, such as age, activity level, and obesity (<xref ref-type="bibr" rid="ref29">29</xref>, <xref ref-type="bibr" rid="ref35">35</xref>, <xref ref-type="bibr" rid="ref42">42</xref>). Since the study population of the present meta-analysis was exclusively obese and overweight patients, whereas previous meta-analyses have had a much broader study population (<xref ref-type="bibr" rid="ref22">22</xref>, <xref ref-type="bibr" rid="ref23">23</xref>), BMI may be one of the factors influencing the discrepancy between the results of the present study and those of previous studies. It has been shown that obese women experience lower levels of pleasure and energy compared to non-obese women, which may partially explain their significantly lower levels of participation in physical activity (<xref ref-type="bibr" rid="ref55">55</xref>), and therefore this may make a smaller difference in the emotional responses of the obese group to the two types of exercise.</p>
</sec>
</sec>
<sec id="sec27">
<label>5</label>
<title>Limitations</title>
<p>Regarding the risk of bias, the FS and PACES analyses showed heterogeneity of the data, a fact that should be considered in the interpretation of the present study. The following reasons for the significant level of heterogeneity in this study may exist: first, the diversity of exercise styles. Different training methods may have different effects on pleasurable and affective responses, leading to instability in the results (e.g., different stimulus to recovery ratios). Second, we must recognize the inherent limitations associated with Meta-analysis. For example, the possibility of publication bias cannot be completely ruled out, i.e., studies with significant results are more likely to be published, which may bias our results. Third, due to limitations in the available literature, we may not have access to all relevant data, which may affect our statistical analysis. Fourth, there may have been inappropriate controls or unconsidered variables in the studies, further contributing to heterogeneity. Although our main results attempted to reduce heterogeneity to a large extent, heterogeneity was not completely eliminated. Therefore, future studies may consider focusing on a particular type with a better study design to cope with the problem when more relevant studies become available. Fifth, some literature data only provided figures without specific values, so Engauge Digitizer was used to estimate and extract the data, which may have some differences with the original data and may lead to inaccurate analysis results.</p>
</sec>
<sec sec-type="conclusions" id="sec28">
<label>6</label>
<title>Conclusion</title>
<p>We conducted a meta-analysis to compare which exercise modality, HIIT or MICT, brings better enjoyment and affective responses in overweight or obese individuals. We found that HIIT caused participants to experience higher enjoyment and similar affect responses compared to MICT, implying that time-efficient training modalities such as HIIT seem to have a place in the choice of exercise prescription for overweight and obese individuals. We therefore conclude that HIIT exercise may be a viable strategy for improving health.</p>
</sec>
</body>
<back>
<sec sec-type="data-availability" id="sec29">
<title>Data availability statement</title>
<p>The original contributions presented in the study are included in the article/<xref rid="SM1" ref-type="supplementary-material">Supplementary material</xref>, further inquiries can be directed to the corresponding author.</p>
</sec>
<sec sec-type="author-contributions" id="sec30">
<title>Author contributions</title>
<p>YL: Conceptualization, Data curation, Writing &#x2013; original draft, Writing &#x2013; review &#x0026; editing. JZ: Conceptualization, Supervision, Writing &#x2013; review &#x0026; editing. HJ: Conceptualization, Methodology, Writing &#x2013; review &#x0026; editing. XM: Conceptualization, Supervision, Writing &#x2013; review &#x0026; editing. JH: Conceptualization, Funding acquisition, Methodology, Writing &#x2013; review &#x0026; editing.</p>
</sec>
<sec sec-type="funding-information" id="sec31">
<title>Funding</title>
<p>The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This research was supported by the National Social Science Fund of China (project 22XTY008).</p>
</sec>
<sec sec-type="COI-statement" id="sec32">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="disclaimer" id="sec33">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec sec-type="supplementary-material" id="sec34">
<title>Supplementary material</title>
<p>The Supplementary material for this article can be found online at: <ext-link xlink:href="https://www.frontiersin.org/articles/10.3389/fpubh.2024.1487789/full#supplementary-material" ext-link-type="uri">https://www.frontiersin.org/articles/10.3389/fpubh.2024.1487789/full#supplementary-material</ext-link></p>
<supplementary-material xlink:href="Supplementary_file_1.docx" id="SM1" mimetype="application/vnd.openxmlformats-officedocument.wordprocessingml.document" xmlns:xlink="http://www.w3.org/1999/xlink"/>
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