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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Public Health</journal-id>
<journal-title>Frontiers in Public Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Public Health</abbrev-journal-title>
<issn pub-type="epub">2296-2565</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpubh.2024.1365124</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Public Health</subject>
<subj-group>
<subject>Original Research</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Burden of carpal tunnel syndrome and its associated factors among construction industry workers in Gondar town, Ethiopia</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name><surname>Bicha</surname> <given-names>Nigus</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
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<contrib contrib-type="author">
<name><surname>Gashaw</surname> <given-names>Moges</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
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<contrib contrib-type="author">
<name><surname>Chanie</surname> <given-names>Samuel Teferi</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
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<contrib contrib-type="author">
<name><surname>Mekie</surname> <given-names>Melisew</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
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<contrib contrib-type="author" corresp="yes">
<name><surname>Yalew</surname> <given-names>Ermias Solomon</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="corresp" rid="c001"><sup>&#x002A;</sup></xref>
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<aff id="aff1"><sup>1</sup><institution>Physiotherapy Unit, Boru Meda Hospital, Amhara Health Bureau</institution>, <addr-line>Dessie</addr-line>, <country>Ethiopia</country></aff>
<aff id="aff2"><sup>2</sup><institution>Department of Physiotherapy, College of Medicine and Health Sciences, University of Gondar</institution>, <addr-line>Gondar</addr-line>, <country>Ethiopia</country></aff>
<aff id="aff3"><sup>3</sup><institution>Discipline of Physiotherapy, Graduate School of Health, Faculty of Health, University of Technology Sydney</institution>, <addr-line>Sydney, NSW</addr-line>, <country>Australia</country></aff>
<author-notes>
<fn fn-type="edited-by" id="fn0001"><p>Edited by: Matthew Hankins, Brighton and Sussex Medical School, United Kingdom</p></fn>
<fn fn-type="edited-by" id="fn0002"><p>Reviewed by: Claudio Colosio, University of Milan, Italy</p><p>Hassan Sadeghi Naeini, Iran University of Science and Technology, Iran</p><p>Venkata Nagaraj Kakaraparthi, King Khalid University, Saudi Arabia</p><p>Sakineh Varmazyar, Qazvin University of Medical Sciences, Iran</p></fn>
<corresp id="c001">&#x002A;Correspondence: Ermias Solomon Yalew, <email>sermias131@gmail.com</email></corresp>
</author-notes>
<pub-date pub-type="epub">
<day>12</day>
<month>06</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="collection">
<year>2024</year>
</pub-date>
<volume>12</volume>
<elocation-id>1365124</elocation-id>
<history>
<date date-type="received">
<day>03</day>
<month>01</month>
<year>2024</year>
</date>
<date date-type="accepted">
<day>21</day>
<month>05</month>
<year>2024</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2024 Bicha, Gashaw, Chanie, Mekie and Yalew.</copyright-statement>
<copyright-year>2024</copyright-year>
<copyright-holder>Bicha, Gashaw, Chanie, Mekie and Yalew</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<sec id="sec1">
<title>Background</title>
<p>Carpal tunnel syndrome is characterized by symptoms such as pain, numbness, or tingling on the anterior surface of the index, middle, or radial half of the ring finger, which is frequently associated with weakness of hand grip, and nocturnal pain and/or numbness resulting from compression of the median nerve at the carpal tunnel between the carpal bones and the transverse ligament. The construction industry involves many activities aside from the building process, such as landscaping, painting, electrical supply, plastering, paving, and telecommunications. Performing such tasks involves repetition of wrist flexion and extension, forceful grip with the hand, and/or vibrations of the hand and arm. This study aimed to assess the prevalence of carpal tunnel syndrome and its associated risk factors among construction workers.</p>
</sec>
<sec id="sec2">
<title>Method</title>
<p>An institutional-based cross-sectional study design was conducted among six construction sectors in Gondar from April to July 2021. An interviewer-administered questionnaire was prepared from the literature with a Katz hand diagram, and a physical examination and a special test (carpal compression test, Phalen&#x2019;s, and Tinel&#x2019;s test) were carried out for those participants who reported pain during the interview. Binary logistic regression was conducted with SPSS 25 to identify the associated risk factors for carpal tunnel syndrome. The strength of the association was detected by the adjusted odds ratio.</p>
</sec>
<sec id="sec3">
<title>Result</title>
<p>A total of 333 study participants aged 18&#x2013;70&#x2009;years were included in this study. Among the participants, 11.7% (AOR: 95%CI: 8.1&#x2013;15.3) had carpal tunnel syndrome. Age, cigarette smoking, work experience, and working with finger-pressing tools were risk factors significantly associated with carpal tunnel syndrome among construction workers with a <italic>p</italic>-value of &#x003C;0.05.</p>
</sec>
<sec id="sec4">
<title>Conclusion</title>
<p>The magnitude of carpal tunnel syndrome was 11.7% among construction workers. Being of older age, having more experience, cigarette smoking, and working with finger-pressing tools were risk factors significantly associated with carpal tunnel syndrome among construction workers. Employers should implement work safety education programs that raise awareness about the risks of cigarette smoking and encourage employers and supervisors to seek early medical intervention and treatment for carpal tunnel syndrome before it becomes a chronic problem.</p>
</sec>
</abstract>
<kwd-group>
<kwd>carpal tunnel syndrome</kwd>
<kwd>construction workers</kwd>
<kwd>work-related musculoskeletal disorder</kwd>
<kwd>Ethiopia</kwd>
<kwd>industry workers</kwd>
</kwd-group>
<counts>
<fig-count count="1"/>
<table-count count="4"/>
<equation-count count="0"/>
<ref-count count="36"/>
<page-count count="9"/>
<word-count count="6067"/>
</counts>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Environmental health and Exposome</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec id="sec5">
<title>Background</title>
<p>Work-related musculoskeletal disorders are a main cause of productivity loss at work, functional impairments, and permanent disability (<xref ref-type="bibr" rid="ref1">1</xref>). Chronic musculoskeletal stresses resulting from strained postures or repetitive, forceful movements can cause chronic musculoskeletal conditions such as tendinitis, epicondylitis, carpal tunnel syndrome, and low back pain (<xref ref-type="bibr" rid="ref2">2</xref>).</p>
<p>Carpal tunnel syndrome (CTS) is characterized by symptoms such as pain, numbness, or tingling on the anterior surface of the index, middle, or radial half of the ring finger, which is frequently associated with weakness of hand grip, and nocturnal pain and/or numbness resulting from compression of the median nerve at the carpal tunnel formed by the carpal bones and the transverse ligament (<xref ref-type="bibr" rid="ref3">3</xref>, <xref ref-type="bibr" rid="ref4">4</xref>). The boundaries of the carpal tunnel include the carpal bones (posteriorly, medially, and laterally) and the transverse carpal ligament, i.e., flexorum retinaculum, anteriorly (<xref ref-type="bibr" rid="ref5">5</xref>).</p>
<p>The construction industry involves many activities aside from the building process, such as landscaping, painting, electrical supply, plastering, paving, and telecommunications (<xref ref-type="bibr" rid="ref6">6</xref>). Performing such tasks involving repetition of wrist flexion and extension, forceful grip with the hand, and/or vibrations of the hand and arm induced by hand-held vibratory tools can damage the median nerve and cause CTS (<xref ref-type="bibr" rid="ref7">7</xref>). In addition, construction workers work in the same position for long periods, suffer overexertion due to carrying and lifting heavy objects, and engage in repetitive tasks. The frequency of the task and the percentage of the time spent on the repetitive tasks are important. Awkward body postures and whole-body vibrations in the construction industry are high-risk factors for CTS and other upper extremity musculoskeletal disorders (<xref ref-type="bibr" rid="ref8">8</xref>).</p>
<p>Carpal tunnel syndrome is a common clinical concern, with annual incidence rates of 0.5&#x2013;5.1 per 1,000 in the general population and 6&#x2013;15 in industry workers (<xref ref-type="bibr" rid="ref9">9</xref>). An 11-year follow-up research showed that the prevalence of CTS among industrial workers was approximately 13% (<xref ref-type="bibr" rid="ref10">10</xref>). In a study performed in the United States, the prevalence of CTS among construction apprentice workers was 8.2% (<xref ref-type="bibr" rid="ref11">11</xref>). According to another study performed in the United States, up to 10% of construction apprentice workers suffer from CTS (<xref ref-type="bibr" rid="ref12">12</xref>). A cross-sectional study performed in Italy reports that the prevalence of CTS is 14.1% (<xref ref-type="bibr" rid="ref3">3</xref>). The prevalence of CTS is 3.8% in the general Finnish population and is 2.5 times more common in women than in men (<xref ref-type="bibr" rid="ref13">13</xref>). A cross-sectional study conducted in Iran found that the prevalence of CTS was 11.9%. In Africa, according to the findings of a study conducted in Egypt, 27.6% of construction workers suffered from CTS with the frequency of symptoms in the following order: hand/wrist pain (93.8%), numbness (65.6%), and nocturnal exacerbations (56.3%) (<xref ref-type="bibr" rid="ref14">14</xref>). A cross-sectional study performed in Ethiopia among bankers revealed that 11.7% of bankers suffered from CTS (<xref ref-type="bibr" rid="ref15">15</xref>).</p>
<p>Previous epidemiological studies revealed that sex, older age, having higher BMI, smoking cigarette, dominant handedness, type of work, speed, movement repetition, bending and twisted, and work experience are related to CTS (<xref ref-type="bibr" rid="ref12">12</xref>, <xref ref-type="bibr" rid="ref14">14</xref>, <xref ref-type="bibr" rid="ref16">16</xref>). There is a lack of data about the prevalence and associated factors of CTS among construction workers in Ethiopia. Therefore, the present study aims to contribute to this area of research by determining the magnitude and factors related to CTS among building construction workers in Gondar, Ethiopia.</p>
</sec>
<sec sec-type="materials|methods" id="sec6">
<title>Methods and materials</title>
<sec id="sec7">
<title>Study design and setting</title>
<p>An institutional-based cross-sectional study was conducted among six construction sectors in Gondar town from April to July 2021.</p>
<p>The town is located 738&#x2009;km northwest of Addis Ababa, the capital of Ethiopia. It has a population of 206,987 (<xref ref-type="bibr" rid="ref17">17</xref>) and has six construction sites, namely, Unity, Rama, Zamra, Siyum, Yirgalem, and Alinando. All construction companies had 510 workers engaged in different working units in all sites.</p>
</sec>
<sec id="sec8">
<title>Source population, study population, and inclusion and exclusion criteria</title>
<p>Adult construction workers who were actively working at construction sites were enrolled in the study. This study included six selected adult construction workers aged at least 18&#x2009;years who were actively involved in construction and provided informed consent. However, construction workers who had wrist trauma, who had diabetes mellitus, who had known pregnancy, were staff office workers, and who had been working for &#x003E;1&#x2009;year were excluded from the study.</p>
</sec>
<sec id="sec9">
<title>Sample size and sampling procedure</title>
<p>The sample size was based on single population proportion formula a sample size was determined; 95% level of significance the proportion of assumptions or expected frequency 27% prevalence of carpal tunnel syndrome done in Africa Egypt marginal error of 5%. Based on the job description, the study populations were stratified into six different strata. The number of samples from each stratum was determined using the proportional allocation formula. Finally, a simple random sampling technique was employed to select 348 samples from the strata.</p>
<p><inline-formula><mml:math id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mo stretchy="false">(</mml:mo><mml:mi mathvariant="normal">z</mml:mi><mml:mspace width="thickmathspace"/><mml:mfenced open="(" close=")"><mml:mrow><mml:mo stretchy="true">/</mml:mo><mml:mn>2</mml:mn></mml:mrow></mml:mfenced><mml:mn>2</mml:mn><mml:mspace width="thickmathspace"/><mml:mfenced open="(" close=")"><mml:mi mathvariant="normal">p</mml:mi></mml:mfenced><mml:mspace width="thickmathspace"/><mml:mfenced open="(" close=")"><mml:mrow><mml:mn>1</mml:mn><mml:mo>&#x2212;</mml:mo><mml:mi mathvariant="normal">p</mml:mi></mml:mrow></mml:mfenced><mml:mspace width="thickmathspace"/><mml:mi mathvariant="normal">d</mml:mi><mml:mn>2</mml:mn></mml:math></inline-formula></p>
<p><inline-formula><mml:math id="M2"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mfenced open="(" close=")"><mml:mn>1.96</mml:mn></mml:mfenced><mml:mn>2</mml:mn><mml:mspace width="thickmathspace"/><mml:mfenced open="(" close=")"><mml:mrow><mml:mn>0.27</mml:mn><mml:mo stretchy="false">)</mml:mo><mml:mspace width="thickmathspace"/><mml:mo stretchy="false">(</mml:mo><mml:mn>1</mml:mn><mml:mo>&#x2212;</mml:mo><mml:mn>0.27</mml:mn></mml:mrow></mml:mfenced><mml:mo>=</mml:mo><mml:mn>302.87</mml:mn></mml:math></inline-formula></p>
<p>(0.05)2 <italic>n</italic>&#x2009;=&#x2009;303</p>
<p><italic>n</italic>&#x2009;=&#x2009;302.87&#x2009;&#x2248;&#x2009;303,</p>
<p>Taking into consideration a 15% non-response rate from <italic>n</italic>&#x2009;=&#x2009;303&#x00D7;15/100&#x2009;=&#x2009;45, the final <italic>n</italic>&#x2009;=&#x2009;348.</p>
<p>A total of 137, 110, 21, 35, 18, and 27 participants from Unity, Rama, Zamra, Siyum, Yirgalem, and Alinando, respectively, were proportionally allocated for each construction site. Then, a simple random sampling technique was used to recruit the actual number of study participants.</p>
</sec>
<sec id="sec10">
<title>Data collection instrument</title>
<p>An interviewer-administered questioner was prepared from the literature, and physical examination was performed to gather information from the participation. Carpal tunnel syndrome was assessed through symptoms reported on the Katz hand diagram and physical examination. Durkan&#x2019;s compression test, the flexion and compression test, Phalen&#x2019;s test, and Tinel&#x2019;s test were performed for all participants.</p>
<p>Construction workers are defined as workers involved in many types of activities aside from the building process, such as landscaping, painting, electrical supply, plastering, paving, and telecommunication.</p>
<p>Durkan&#x2019;s or carpal compression test consists of applying direct pressure on the carpal tunnel and the underlying median nerve. This task is performed by an examiner who exerts even pressure, with both thumbs, to the median nerve in the carpal tunnel. The examiner presses the thumbs over the carpal tunnel and holds the pressure for 30&#x2009;s. An onset of pain or paresthesia in the median nerve distribution within 30&#x2009;s is a positive result of the test (<xref ref-type="bibr" rid="ref18">18</xref>).</p>
<p>The flexion and compression test was performed with the elbow extended, the forearm in supination, and the wrist flexed to 60&#x00B0;. Even and constant digital pressure was then applied with one thumb over the median nerve at the carpal tunnel. The time before the development of paresthesia or numbness in the distribution of the median nerve was recorded, and the test was considered positive if symptoms occurred within 30&#x2009;s (<xref ref-type="bibr" rid="ref19">19</xref>).</p>
<p>The wrist flexion test (Phalen&#x2019;s test) is positive when, after full flexion of the wrist for up to 60&#x2009;s, the patient experiences symptoms of paresthesia or numbness within the distal territory of the median nerve, similar to those of which he complains during the night or aggravation of the existing paresthesia if they are present permanently (<xref ref-type="bibr" rid="ref20">20</xref>, <xref ref-type="bibr" rid="ref21">21</xref>).</p>
<p>Tinel&#x2019;s test involves a tap over the median nerve as it passes through the carpal tunnel in the wrist A positive response is defined as a sensation of tingling in the distribution of the median nerve over the hand (<xref ref-type="bibr" rid="ref21">21</xref>).</p>
<p>The Katz Hand diagram is a self-administered hand diagram for the diagnosis of carpal tunnel syndrome, including symptoms such as tingling, numbness, or decreased sensation with or without pain in at least two of digits 1, 2, or 3, as well as wrist pain or radiation proximal to the wrist, but excluding symptoms in the palm and dorsum of the hand (<xref ref-type="bibr" rid="ref22">22</xref>).</p>
<p>Independent variables such as sociodemographic variables and repetitive wrist movement, especially when the self-reported time spent in activities with the wrist flexed or extended was 20&#x2009;h/week (<xref ref-type="bibr" rid="ref23">23</xref>). Working with hands above the shoulder level is defined as working with hands above the shoulder level for at least 1&#x2009;h (<xref ref-type="bibr" rid="ref24">24</xref>).</p>
<p>Smoker: Individuals who reported smoking at least one cigarette daily will be considered smokers.</p>
<p>Working with vibratory tools is defined as working with a hand-vibratory tool for at least 2&#x2009;h (<xref ref-type="bibr" rid="ref24">24</xref>).</p>
<p>Body mass index can be measured as weight in kilogram divided by square of height in meters (kg/m2). Based on the BMI, the workers were categorized as under-weight (&#x003C;18.5&#x2009;kg/m<sup>2</sup>), normal (18.5&#x2013;24.99&#x2009;kg/m<sup>2</sup>), overweight (&#x003E;25&#x2013;29.9&#x2009;kg/m<sup>2</sup>), and obesity (&#x003E;30&#x2009;kg/m<sup>2</sup>) (<xref ref-type="bibr" rid="ref25">25</xref>).</p>
<p>Awkward posture is defined as using bending or twisted posture during work (<xref ref-type="bibr" rid="ref26">26</xref>).</p>
<p>Alcohol Drinking is defined as the consumption of any kind of alcohol at least for two times per week for different purposes.</p>
</sec>
<sec id="sec11">
<title>Data quality assurance</title>
<p>To ensure the quality of the data, the data collectors and supervisors were trained for 1&#x2009;day before the actual data collection process on how to approach the participants, the objective of the study, and ethical issue. The data collection tool was pretested before the actual data collection process to check for the accuracy of responses, language clarity, and appropriateness of the tools. The questionnaire was pretested by taking 5% (<xref ref-type="bibr" rid="ref17">17</xref>) of the sample population, and we found that the interclass correlation coefficient (ICC) value of the tool was 0.86. The supervisor checked for the completeness and consistency of the data.</p>
</sec>
<sec id="sec12">
<title>Data processing and analysis</title>
<p>The collected data were checked for completeness and clarity, coded, and then entered in EpI data version 4.6.0.4 and analyzed by using SPSS version 25. Descriptive, bivariate, and multivariate analyses had been used with a <italic>p</italic>-value &#x003C;0.2 in the bivariate model further analyzed using the multivariate model. A logistic regression analysis was used to control possible confounders and to examine the association between different independent variables. The strength of the associations was determined using an adjusted odds ratio (AOR) with a 95% confidence interval (CI) with a <italic>p</italic>-value of less than 0.05. The model fitness was checked using the Hosmer and Lemeshow test (0.865).</p>
</sec>
</sec>
<sec sec-type="results" id="sec13">
<title>Results</title>
<sec id="sec14">
<title>Sociodemographic characteristics of the participant</title>
<p>A total of 333 study participants were included in this study with a response rate of 95.7%; the reasons for non-responses were lack of time and lack of interest. The age range of the study participants was between 18 and 70&#x2009;years; a majority of the study participants (217) (65.2%) were found in the age range of &#x003C;30&#x2009;years old, and the mean age of the participants was 30.83&#x2009;years with a standard deviation of 9.183. Men included the majority of the participants (219) (65.8%), and women composed 114 of the participants (34.2%). More than half of the participants (66.7%) were urban dwellers, and 183 (55%) participants were married. The education level of most participants (125) (37.6%) were complete primary school, and 319 (95.8) are right-handed. In addition, 269 (80.8%) participants had normal body mass index (18.5&#x2013;24.99), out of which 53 (15.9%) were underweight (<xref ref-type="table" rid="tab1">Table 1</xref>).</p>
<table-wrap position="float" id="tab1">
<label>Table 1</label>
<caption>
<p>Sociodemographic characteristics of carpal tunnel syndrome in construction workers in Gondar, Ethiopia, June 2021 (<italic>n</italic>&#x2009;=&#x2009;333).</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Variables</th>
<th align="center" valign="top">Frequency (<italic>n</italic>)</th>
<th align="center" valign="top">Percentage (%)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" colspan="3">Sex</td>
</tr>
<tr>
<td align="left" valign="top">Male</td>
<td align="center" valign="top">219</td>
<td align="center" valign="top">65.8</td>
</tr>
<tr>
<td align="left" valign="top">Female</td>
<td align="center" valign="top">114</td>
<td align="center" valign="top">34.2</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Age in years</td>
</tr>
<tr>
<td align="left" valign="top">&#x003C;30</td>
<td align="center" valign="top">217</td>
<td align="center" valign="top">65.2</td>
</tr>
<tr>
<td align="left" valign="top">30&#x2013;45</td>
<td align="center" valign="top">89</td>
<td align="center" valign="top">26.7</td>
</tr>
<tr>
<td align="left" valign="top">&#x2265;46</td>
<td align="center" valign="top">27</td>
<td align="center" valign="top">8.1</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">BMI</td>
</tr>
<tr>
<td align="left" valign="top">Underweight (&#x003C;18.5)</td>
<td align="center" valign="top">53</td>
<td align="center" valign="top">15.9</td>
</tr>
<tr>
<td align="left" valign="top">Normal (18.5&#x2013;24.99)</td>
<td align="center" valign="top">269</td>
<td align="center" valign="top">80.8</td>
</tr>
<tr>
<td align="left" valign="top">Overweight (&#x003E;25&#x2013;29.9)</td>
<td align="center" valign="top">11</td>
<td align="center" valign="top">3.3</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Marital status</td>
</tr>
<tr>
<td align="left" valign="top">Married</td>
<td align="center" valign="top">183</td>
<td align="center" valign="top">55</td>
</tr>
<tr>
<td align="left" valign="top">Single</td>
<td align="center" valign="top">150</td>
<td align="center" valign="top">45</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Level of education</td>
</tr>
<tr>
<td align="left" valign="top">No formal education</td>
<td align="center" valign="top">83</td>
<td align="center" valign="top">24.9</td>
</tr>
<tr>
<td align="left" valign="top">Complete primary school</td>
<td align="center" valign="top">125</td>
<td align="center" valign="top">37.5</td>
</tr>
<tr>
<td align="left" valign="top">Complete secondary school</td>
<td align="center" valign="top">93</td>
<td align="center" valign="top">27.9</td>
</tr>
<tr>
<td align="left" valign="top">Diploma/degree</td>
<td align="center" valign="top">32</td>
<td align="center" valign="top">9.6</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Residence</td>
</tr>
<tr>
<td align="left" valign="top">Rural</td>
<td align="center" valign="top">111</td>
<td align="center" valign="top">33.3</td>
</tr>
<tr>
<td align="left" valign="top">Urban</td>
<td align="center" valign="top">222</td>
<td align="center" valign="top">66.7</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Handedness</td>
</tr>
<tr>
<td align="left" valign="top">Right</td>
<td align="center" valign="top">319</td>
<td align="center" valign="top">95.8</td>
</tr>
<tr>
<td align="left" valign="top">Left</td>
<td align="center" valign="top">14</td>
<td align="center" valign="top">4.2</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="sec15">
<title>Behavior characteristics of carpal tunnel syndrome in construction workers in Gondar Ethiopia, June 2021, (<italic>n</italic>&#x2009;=&#x2009;333)</title>
<p>A total of 92 (27.6%) study participants consumed alcohol, and most of them, i.e., 296 (88.9%) of them, were non-smokers (<xref ref-type="table" rid="tab2">Table 2</xref>).</p>
<table-wrap position="float" id="tab2">
<label>Table 2</label>
<caption>
<p>Behavior characteristics of carpal tunnel syndrome in construction workers.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Variables</th>
<th align="center" valign="top">Frequency (<italic>n</italic>)</th>
<th align="center" valign="top">Percentage (%)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" colspan="3">Alcohol consumption</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">92</td>
<td align="center" valign="top">27.6</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">241</td>
<td align="center" valign="top">72.4</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Cigarette smoking</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">37</td>
<td align="center" valign="top">11.1</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">296</td>
<td align="center" valign="top">88.9</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Regular exercise</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">26</td>
<td align="center" valign="top">7.8</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">307</td>
<td align="center" valign="top">92.2</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="sec16">
<title>Work-related characteristics of carpal tunnel syndrome in construction workers in Gondar Ethiopia, June 2021, (<italic>n</italic>&#x2009;=&#x2009;333)</title>
<p>Most participants had a duration of employment of less than 5&#x2009;years (2,430) (73%), and the highest percentage of participants include daily wage laborers (118) (35.4%), carpenters (76) (22.8%), and only 10 (3%) were painters. In addition, 236 (70.9%) participants did not work with vibratory tools, and most of them had experienced bending and twisting of the hand (322) (96.7). Most of the participants (289) (86.8%) used their wrist repetitively, and 289 (86.8%) workers had used their hand to perform activities requiring involvement above shoulder level, and 278 (83.5) performed load carrying manually (<xref ref-type="table" rid="tab3">Table 3</xref>).</p>
<table-wrap position="float" id="tab3">
<label>Table 3</label>
<caption>
<p>Work-related characteristics of carpal tunnel syndrome in construction workers.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Variables</th>
<th align="center" valign="top">Frequency (<italic>n</italic>)</th>
<th align="center" valign="top">Percentage (%)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" colspan="3">Work experience</td>
</tr>
<tr>
<td align="left" valign="top">&#x003C;5&#x2009;years</td>
<td align="center" valign="top">243</td>
<td align="center" valign="top">73</td>
</tr>
<tr>
<td align="left" valign="top">&#x003E;5&#x2009;years</td>
<td align="center" valign="top">90</td>
<td align="center" valign="top">27</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Occupational history</td>
</tr>
<tr>
<td align="left" valign="top">Carpenter</td>
<td align="center" valign="top">76</td>
<td align="center" valign="top">22.8</td>
</tr>
<tr>
<td align="left" valign="top">Painter</td>
<td align="center" valign="top">10</td>
<td align="center" valign="top">3</td>
</tr>
<tr>
<td align="left" valign="top">Daily labor worker</td>
<td align="center" valign="top">118</td>
<td align="center" valign="top">35.4</td>
</tr>
<tr>
<td align="left" valign="top">Masonry</td>
<td align="center" valign="top">39</td>
<td align="center" valign="top">11.7</td>
</tr>
<tr>
<td align="left" valign="top">Electrical</td>
<td align="center" valign="top">12</td>
<td align="center" valign="top">3.6</td>
</tr>
<tr>
<td align="left" valign="top">Plasterer</td>
<td align="center" valign="top">42</td>
<td align="center" valign="top">12.6</td>
</tr>
<tr>
<td align="left" valign="top">Other</td>
<td align="center" valign="top">36</td>
<td align="center" valign="top">10.8</td>
</tr>
<tr>
<td align="left" valign="top">Working with vibratory tools</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">97</td>
<td align="center" valign="top">29.1</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">236</td>
<td align="center" valign="top">70.9</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Bend and Twist</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">322</td>
<td align="center" valign="top">96.7</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">11</td>
<td align="center" valign="top">3.3</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Hands above shoulder</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">289</td>
<td align="center" valign="top">86.8</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">44</td>
<td align="center" valign="top">13.2</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Carrying load</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">278</td>
<td align="center" valign="top">83.5</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">55</td>
<td align="center" valign="top">16.5</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Repetitive moments on the hand</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">230</td>
<td align="center" valign="top">69.1</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">103</td>
<td align="center" valign="top">31.9</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Working with finger pinching tools</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">29</td>
<td align="center" valign="top">8.7</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">304</td>
<td align="center" valign="top">91.3</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Working with finger pressing tools</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">40</td>
<td align="center" valign="top">12.0</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">293</td>
<td align="center" valign="top">88.0</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="sec17">
<title>Prevalence of carpal tunnel syndrome among construction workers</title>
<p>Among all 333 study participants, the annual prevalence of carpal tunnel syndrome was 11.7% with 95% CI, as shown in <xref ref-type="fig" rid="fig1">Figure 1</xref>. The prevalence of carpal tunnel syndrome was significantly higher (<italic>n</italic>&#x2009;=&#x2009;30; 13.7%) among men and those who had a normal body mass index (<italic>n</italic>&#x2009;=&#x2009;29; 10.8%), and in those with no formal education (<italic>n</italic>&#x2009;=&#x2009;18; 21.7%). In terms of residence, among 222 urban residents, 26 (11.7%) had carpal tunnel syndrome. According to hand dominance, 39 (12.9%) were right-handed positive, 280 (87.8%) were right-handed negative, 14 were left-handed positive, and 100% were left-handed negative; in terms of those who consumed alcohol, 17 (18.5%) had CTS; and in terms of those who were cigarette smokers, 13 (35.1%) had CTS. Regarding the part of the hand affected, the right hand was affected in 20 (51.6%), the left hand in 7 (17.9%), and both hands in 12 (30.8%).</p>
<fig position="float" id="fig1">
<label>Figure 1</label>
<caption>
<p>Prevalence of carpal tunnel syndrome among construction workers.</p>
</caption>
<graphic xlink:href="fpubh-12-1365124-g001.tif"/>
</fig>
</sec>
<sec id="sec18">
<title>Factors associated with carpal tunnel syndrome among construction workers</title>
<p>A binary logistic regression analysis was executed on each of the factors that were found to be significantly associated with the prevalence of carpal tunnel syndrome among construction workers. Age, sex, marital status, alcohol consumption, cigarette smoking, work experience, working with vibratory tools, having repetitive movements on the hand, working with finger-pressing tools, and working with finger-pinching tools were significantly associated with the prevalence of carpal tunnel syndrome among construction workers at a <italic>p</italic>-value of &#x003C;0.2 in the bivariable logistic regression. Those variables were included in the multivariable logistic regression model and further analyzed to adjust for potential confounders and identify predictors of the prevalence of carpal tunnel syndrome among construction workers. In a multivariable logistic regression analysis, age, cigarette smoking, work experience, and working with finger-pressing tools (tools) were variables significantly associated with the prevalence of carpal tunnel syndrome among construction workers.</p>
<p>A construction worker over the age of 45&#x2009;years are at 3.723 times odds of developing carpal tunnel syndrome compared with construction workers under the age of 30&#x2009;years [AOR: 3.723, CI 95% (1.085&#x2013;12.776)]. Individuals who smoke cigarettes had a 3.19-fold increased risk of developing carpal tunnel syndrome compared to construction workers who had no such history of cigarette smoking [AOR: 3.197; 95% CI: (1.153&#x2013;8.866)]. Those workers who had a work experience greater than or equal to 5&#x2009;years are 6.5 times more likely to develop carpal tunnel syndrome compared to those with less than 5&#x2009;years of work experience [AOR: CI, 95% 6.532 (2.488&#x2013;17.144)]. Individuals working with finger-pressing materials or tools are at 4.575 times odds of having carpal tunnel syndrome compared with construction workers not working with finger-pressing materials or tools [AOR: CI, 95% 4.574 (1.230&#x2013;17.010)] (<xref ref-type="table" rid="tab4">Table 4</xref>).</p>
<table-wrap position="float" id="tab4">
<label>Table 4</label>
<caption>
<p>Factors associated with carpal tunnel syndrome among construction workers.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top" rowspan="2">Variables</th>
<th align="center" valign="top" colspan="2">Carpal tunnel syndrome</th>
<th align="center" valign="top" rowspan="2">Univariate COR (95%CI)</th>
<th align="center" valign="top" rowspan="2">Multivariate AOR (95%CI)</th>
<th align="center" valign="top" rowspan="2"><italic>p</italic>-value</th>
</tr>
<tr>
<th align="center" valign="top">No</th>
<th align="center" valign="top">Yes</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" colspan="6">Age in years</td>
</tr>
<tr>
<td align="left" valign="top">&#x003C;30</td>
<td align="center" valign="top">203</td>
<td align="center" valign="top">14</td>
<td align="center" valign="top">1</td>
<td align="center" valign="top">_</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">31&#x2013;45</td>
<td align="center" valign="top">76</td>
<td align="center" valign="top">13</td>
<td align="center" valign="top">2.480 (1.115&#x2013;5.518)</td>
<td align="center" valign="top">1.454 (0.539&#x2013;3.921)</td>
<td align="center" valign="top">0.460</td>
</tr>
<tr>
<td align="left" valign="top">&#x003E;45</td>
<td align="center" valign="top">15</td>
<td align="center" valign="top">12</td>
<td align="center" valign="top">11.600 (4.565&#x2013;29.474)</td>
<td align="center" valign="top">3.723 (1.085&#x2013;12.776.)</td>
<td align="center" valign="top">0.037<sup>&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top" colspan="6">Sex</td>
</tr>
<tr>
<td align="left" valign="top">Male</td>
<td align="center" valign="top">189</td>
<td align="center" valign="top">30</td>
<td align="center" valign="top">1.852 (0.847&#x2013;4.049)</td>
<td align="center" valign="top">0.454 (0.163&#x2013;1.269)</td>
<td align="center" valign="top">0.132</td>
</tr>
<tr>
<td align="left" valign="top">Female</td>
<td align="center" valign="top">105</td>
<td align="center" valign="top">9</td>
<td align="center" valign="top">1</td>
<td align="center" valign="top">_</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" colspan="6">Marital status</td>
</tr>
<tr>
<td align="left" valign="top">Married</td>
<td align="center" valign="top">156</td>
<td align="center" valign="top">27</td>
<td align="center" valign="top">1.990 (0.971&#x2013;4.079)</td>
<td align="center" valign="top">0.735 (0.288&#x2013;1.875)</td>
<td align="center" valign="top">0.519</td>
</tr>
<tr>
<td align="left" valign="top">single</td>
<td align="center" valign="top">138</td>
<td align="center" valign="top">12</td>
<td align="center" valign="top">1</td>
<td align="center" valign="top">_</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" colspan="6">Alcohol consumption</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">75</td>
<td align="center" valign="top">17</td>
<td align="center" valign="top">2.256 (1.377&#x2013;4.476)</td>
<td align="center" valign="top">1.554 (0.640&#x2013;3.774)</td>
<td align="center" valign="top">0.330</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">219</td>
<td align="center" valign="top">22</td>
<td align="center" valign="top">1</td>
<td align="center" valign="top">_</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" colspan="6">Cigarette smoking</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">24</td>
<td align="center" valign="top">13</td>
<td align="center" valign="top">5.628 (2.564&#x2013;12.343)</td>
<td align="center" valign="top">3.197 (1.153&#x2013;8.866)</td>
<td align="center" valign="top">0.026<sup>&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">270</td>
<td align="center" valign="top">26</td>
<td align="center" valign="top">1</td>
<td align="center" valign="top">_</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" colspan="6">Work experiences in years</td>
</tr>
<tr>
<td align="left" valign="top">&#x003E;5</td>
<td align="center" valign="top">232</td>
<td align="center" valign="top">11</td>
<td align="center" valign="top">1</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="top">&#x003E;&#x2009;=&#x2009;5</td>
<td align="center" valign="top">62</td>
<td align="center" valign="top">28</td>
<td align="center" valign="top">9.525 (4.492&#x2013;20.197)</td>
<td align="center" valign="top">6.532 (2.488&#x2013;17.144)</td>
<td align="center" valign="top">0.000<sup>&#x002A;&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top" colspan="6">Working with vibratory tools</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">80</td>
<td align="center" valign="top">17</td>
<td align="center" valign="top">2.067 (1.044&#x2013;4.93)</td>
<td align="center" valign="top">1.222 (0.508&#x2013;2.940)</td>
<td align="center" valign="top">0.654</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">214</td>
<td align="center" valign="top">22</td>
<td align="center" valign="top">1</td>
<td align="center" valign="top">_</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" colspan="6">Repetitive moments on the hand</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">196</td>
<td align="center" valign="top">34</td>
<td align="center" valign="top">3.400 (1.289&#x2013;8.965)</td>
<td align="center" valign="top">3.125 (0.975&#x2013;10.015)</td>
<td align="center" valign="top">0.055</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">98</td>
<td align="center" valign="top">5</td>
<td align="center" valign="top">1</td>
<td align="center" valign="top">_</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" colspan="6">Working with finger pressing tool</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">29</td>
<td align="center" valign="top">11</td>
<td align="center" valign="top">3.590 (1.620&#x2013;7.956)</td>
<td align="center" valign="top">4.574 (1.230&#x2013;17.010)</td>
<td align="center" valign="top">0.023<sup>&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">265</td>
<td align="center" valign="top">28</td>
<td align="center" valign="top">1</td>
<td align="center" valign="top">_</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" colspan="6">Working with finger pinching tool</td>
</tr>
<tr>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">21</td>
<td align="center" valign="top">8</td>
<td align="center" valign="top">3.355 (1.371&#x2013;8.211)</td>
<td align="center" valign="top">0.986 (0.225&#x2013;4.312)</td>
<td align="center" valign="top">0.985</td>
</tr>
<tr>
<td align="left" valign="top">No</td>
<td align="center" valign="top">273</td>
<td align="center" valign="top">31</td>
<td align="center" valign="top">1</td>
<td align="center" valign="top">_</td>
<td/>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>1&#x2009;=&#x2009;reference category; AOR, adjusted odds ratio; CI, confidence interval; COR, crude odds ratio; &#x002A;&#x2009;=&#x2009;statistically significant at a <italic>p</italic>-value of&#x2009;&#x003C;&#x2009;0.05.</p>
</table-wrap-foot>
</table-wrap>
</sec>
</sec>
<sec sec-type="discussion" id="sec19">
<title>Discussion</title>
<p>The present study aimed to contribute to the research in determining the magnitude and factors related to CTS among 333 building construction workers in Gondar, Ethiopia. Our study results revealed that, out of the total participants, 39 (11.7%) experienced CTS. The prevalence of carpal tunnel syndrome was significantly higher (13.7% <italic>n</italic>&#x2009;=&#x2009;30) among men. According to handedness and the prevalence and distribution of CTS among the 39 carpal tunnel syndrome construction workers, 71.8% of workers diagnosed with CTS had pain, 59% had tingling, and 71.8% of them experienced numbness and 25.6% experienced decreased sensation. In addition, the highest prevalence of CTS was among electricians (33.3%), followed by painters (30%). The lowest was among daily labor workers (5.1%). In terms of the affected hand, the right hand was affected in 20 (51.6), the left hand in 7 (17.9%), and both hands in 12 (30.8%) participants.</p>
<p>Our study&#x2019;s prevalence rate (11.7%) is similar to the prevalence rate found in a cross-sectional study conducted in Iran, with a prevalence rate of 11.9% (<xref ref-type="bibr" rid="ref27">27</xref>). In the US, carpal tunnel syndrome (CTS) affects up to 10% of construction apprentices (<xref ref-type="bibr" rid="ref12">12</xref>), and in a cross-sectional study conducted in Germany, the prevalence of CTS in working populations was 10.9%, and a cross-sectional study conducted in Italy reported that the prevalence of CTS was 14.1% (<xref ref-type="bibr" rid="ref3">3</xref>). The reason for the abovementioned prevalence rates could be the that most of the industrial workers are prone to different activities such as carrying load, having repetitive movements on the hand, and working with vibratory tools. Repetition of wrist flexion and extension forceful grip with the hand and/or vibrations of the hand and arm induced by hand-held vibratory tools are the greatest and the most accepted occupational risk factors that can damage the median nerve and cause CTS (<xref ref-type="bibr" rid="ref16">16</xref>).</p>
<p>In contrast, the prevalence of CTS among construction workers in our study was higher than the prevalence of CTS among construction workers based on national surveys. The prevalence of CTS among construction workers determined in this study is much higher than that in the 1988 National Health Interview Survey (Occupational Health Supplement) involving 30,090 &#x201C;recent workers,&#x201D; which revealed a 1-year period prevalence of 2.12% for self-reported CTS in the construction industry (<xref ref-type="bibr" rid="ref16">16</xref>).</p>
<p>In addition, the estimated prevalence rates for CTS have been 1&#x2013;5% in the general population owing to the fact that the general population may be less experienced with the work load that is common to the construction industry. Since most of the workers in the construction industry are prone to different activities such as carrying load, having repetitive movements on the hand, and working with vibratory tools, the prevalence of CTS among apprentice construction workers was 8.2% in the U.S. (<xref ref-type="bibr" rid="ref11">11</xref>). The possible reason for the difference may be the level of development and strengths of occupational health and safety services.</p>
<p>Furthermore, in a study involving 200 construction apprentices in Hungary, no cases of CTS were found among apprentices (<xref ref-type="bibr" rid="ref28">28</xref>). The possible reason for the difference may be that the average age of the Hungarian apprentices was 17&#x2009;years and those in U.S.A was 27, and in our study, the average age was 30, which is 13 and 3&#x2009;years, respectively, lesser than the population in our study. The very young age and lack of occupational exposure to wrist intensive activities among the Hungarian workers likely accounted for the absence of CTS.</p>
<p>On the contrary, 11.7% of construction workers doing manual work were diagnosed with CTS, and the prevalence rate is less than that found in France (19.7%) (<xref ref-type="bibr" rid="ref29">29</xref>). This difference may be due to their larger sample size they used (1,275 participants) (mean age: 38.2&#x2009;years). In addition, the prevalence rate in Egypt was 27.6%, and the possible justification for the difference may be due to their operational definition variation with this study. We used the Katz hand diagram positive findings in at least two of four clinical tests, the four flexion and compression test, carpal compression test, Phalen&#x2019;s test, and Tinel&#x2019;s test, and both occupational exposure and age are likely factors that account for differences among workers in these countries (<xref ref-type="bibr" rid="ref30">30</xref>).</p>
<p>The findings of this study show that the age of the participants is significantly associated with carpal tunnel syndrome, as construction workers above 45&#x2009;years of age were more likely to have carpal tunnel syndrome. This finding supported by the study carried out in Thailand (<xref ref-type="bibr" rid="ref31">31</xref>). The possible explanation may be there is histological change in the transverse carpal ligament with age increase (become older) (<xref ref-type="bibr" rid="ref32">32</xref>).</p>
<p>Participants who had a history of cigarette smoking were more likely to develop CTS than other participants who had no history of cigarette smoking. This finding was similar to a study conducted in Iran. In addition, Nathan et al. found a significant correlation between cigarette smoking and CTS (<xref ref-type="bibr" rid="ref10">10</xref>, <xref ref-type="bibr" rid="ref27">27</xref>). The reason for this correlation could be that smoking can impair the vascular supply of the median nerve, thereby potentially increasing the susceptibility of the nerve to physical workloads, and prolonged tissue ischemia due to smoking may lead to median nerve degeneration and fibrosis (<xref ref-type="bibr" rid="ref33">33</xref>).</p>
<p>Work experience of over 5&#x2009;years among construction workers significantly increased the odds of carpal tunnel syndrome compared to those with less than 5&#x2009;years of work experience. This finding is supported by a study conducted on 996 construction workers, where a longer duration of work has been found as a risk factor for CTS and corroborates with a study conducted in Egypt (<xref ref-type="bibr" rid="ref14">14</xref>, <xref ref-type="bibr" rid="ref34">34</xref>, <xref ref-type="bibr" rid="ref35">35</xref>).</p>
<p>Furthermore, significant associations were observed between working with finger-pressing tools and carpal tunnel syndrome among construction workers (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.023). The odds of working with finger-pressing tools were nearly five time more for the development of carpal tunnel syndrome than among those who were not working with finger-pressing tools among construction workers. This finding is supported by the review conducted in Canada (<xref ref-type="bibr" rid="ref36">36</xref>), which suggests that the external load on the hand, especially on the fingers, significantly increases the pressure on the carpal tunnel (<xref ref-type="bibr" rid="ref5">5</xref>). Overall, this finding is crucial for healthcare providers and policymakers in developing targeted interventions and preventive measures. It has the potential to make a significant contribution to understanding carpal tunnel syndrome (CTS) among construction industry workers in Gondar, Ethiopia and to inform strategies for its prevention, early detection, and management as an occupational health concern.</p>
</sec>
<sec sec-type="conclusions" id="sec20">
<title>Conclusion</title>
<p>The magnitude of carpal tunnel syndrome was 11.7% among construction workers in Gondar town. Older age, having more work experience, cigarette smoking, and working with finger-pressing tools were significantly associated with carpal tunnel syndrome among construction workers. Implementations of education programs that raise awareness about the risk of cigarette smoking along with encouragement from employers and supervisors to seek early medical intervention and treatment of carpal tunnel syndrome can help prevent the disease progression before they become a chronic problem. In Ethiopia, the reporting system for work-related degenerative conditions (CTS and LBP) is less robust and workers&#x2019; compensation programs are inadequate. Moreover, no compensations had been granted for the identified cases. However, the authors recommend that, in order to improve occupational health and safety standards, increased access to healthcare services and the strengthening of workers&#x2019; rights and compensation programs are essential for addressing work-related conditions such as CTS in low-income countries.</p>
</sec>
<sec sec-type="data-availability" id="sec21">
<title>Data availability statement</title>
<p>The original contributions presented in the study are included in the article/<xref ref-type="supplementary-material" rid="SM1">Supplementary material</xref>, further inquiries can be directed to the corresponding author.</p>
</sec>
<sec sec-type="ethics-statement" id="sec22">
<title>Ethics statement</title>
<p>The studies involving humans were approved by the Institutional Review Board of the University of Gondar College of Medicine and Health Science. The studies were conducted in accordance with the local legislation and institutional requirements. The participants provided their written informed consent to participate in this study.</p>
</sec>
<sec sec-type="author-contributions" id="sec23">
<title>Author contributions</title>
<p>NB: Writing &#x2013; original draft, Supervision, Project administration, Methodology, Investigation, Conceptualization. MG: Writing &#x2013; review &#x0026; editing, Project administration, Methodology, Investigation, Formal analysis, Data curation. SC: Writing &#x2013; review &#x0026; editing, Visualization, Validation, Software, Resources, Conceptualization. MM: Writing &#x2013; original draft, Supervision, Methodology, Investigation, Formal analysis, Conceptualization. EY: Writing &#x2013; original draft, Methodology, Formal analysis, Conceptualization.</p>
</sec>
</body>
<back>
<sec sec-type="funding-information" id="sec24">
<title>Funding</title>
<p>The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This study was fully funded by the Amhara Health Bureau for postgraduate study award of the primary author. The funder did not involve in the design of the study, data collection, analysis, and interpretation.</p>
</sec>
<ack>
<p>First, we would also like to express my gratitude to the University of Gondar for providing their ethical permission and Amhara Health Bureau for financial support. Finally, we would like to express my heartfelt appreciation to my data collectors and study participants for their courtesy and cooperation throughout the data collection process.</p>
</ack>
<sec sec-type="COI-statement" id="sec25">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="disclaimer" id="sec26">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec sec-type="disclaimer" id="sec27">
<title>Author disclaimer</title>
<p>The views presented in the article belongs to the authors and do not necessarily express the views of the funding and affiliated organization.</p>
</sec>
<sec sec-type="supplementary-material" id="sec28">
<title>Supplementary material</title>
<p>The Supplementary material for this article can be found online at: <ext-link xlink:href="https://www.frontiersin.org/articles/10.3389/fpubh.2024.1365124/full#supplementary-material" ext-link-type="uri">https://www.frontiersin.org/articles/10.3389/fpubh.2024.1365124/full#supplementary-material</ext-link></p>
<supplementary-material xlink:href="Data_Sheet_1.docx" id="SM1" mimetype="application/vnd.openxmlformats-officedocument.wordprocessingml.document" xmlns:xlink="http://www.w3.org/1999/xlink"/>
</sec>
<fn-group>
<title>Abbreviations</title>
<fn fn-type="abbr"><p>AOR, Adjusted odds ratio; BMI, Body Mass Index; CI, Confidence Interval; CTS, Carpal tunnel syndrome; OR, Odds ratio; SPSS, Statistical package for social science; USA, United States of America; WHO, World Health Organization; WRMSD, Work-related musculoskeletal disorders.</p></fn>
</fn-group>
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