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<?covid-19-tdm?>
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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Public Health</journal-id>
<journal-title>Frontiers in Public Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Public Health</abbrev-journal-title>
<issn pub-type="epub">2296-2565</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpubh.2022.844560</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Public Health</subject>
<subj-group>
<subject>Original Research</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Decline in Mental Health in the Beginning of the COVID-19 Outbreak Among European Older Adults&#x02014;Associations With Social Factors, Infection Rates, and Government Response</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name><surname>L&#x000FC;decke</surname> <given-names>Daniel</given-names></name>
<xref ref-type="corresp" rid="c001"><sup>&#x0002A;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/779763/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>von dem Knesebeck</surname> <given-names>Olaf</given-names></name>
<uri xlink:href="http://loop.frontiersin.org/people/1002523/overview"/>
</contrib>
</contrib-group>
<aff><institution>Institute of Medical Sociology, University Medical Center Hamburg-Eppendorf</institution>, <addr-line>Hamburg</addr-line>, <country>Germany</country></aff>
<author-notes>
<fn fn-type="edited-by"><p>Edited by: Katherine Henrietta Leith, University of South Carolina, United States</p></fn>
<fn fn-type="edited-by"><p>Reviewed by: Patricia M. Alt, Towson University, United States; Thomas Edward Strayer III, Vanderbilt University Medical Center, United States</p></fn>
<corresp id="c001">&#x0002A;Correspondence: Daniel L&#x000FC;decke <email>d.luedecke&#x00040;uke.de</email></corresp>
<fn fn-type="other" id="fn001"><p>This article was submitted to Aging and Public Health, a section of the journal Frontiers in Public Health</p></fn></author-notes>
<pub-date pub-type="epub">
<day>14</day>
<month>03</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="collection">
<year>2022</year>
</pub-date>
<volume>10</volume>
<elocation-id>844560</elocation-id>
<history>
<date date-type="received">
<day>28</day>
<month>12</month>
<year>2021</year>
</date>
<date date-type="accepted">
<day>18</day>
<month>02</month>
<year>2022</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x000A9; 2022 L&#x000FC;decke and von dem Knesebeck.</copyright-statement>
<copyright-year>2022</copyright-year>
<copyright-holder>L&#x000FC;decke and von dem Knesebeck</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<abstract>
<sec>
<title>Objective</title>
<p>Governments across the world have deployed a wide range of non-pharmaceutical interventions (NPI) to mitigate the spread of COVID-19. Certain NPIs, like limiting social contacts or lockdowns, had negative consequences for mental health in the population. Especially elder people are prone to mental illnesses during the current pandemic. This article investigates how social factors, infections rates, and stringency of NPIs are associated with a decline in mental health in different European countries.</p>
</sec>
<sec>
<title>Methods</title>
<p>Data stem from the eighth wave of the SHARE survey. Additional data sources were used to build macro indicators for infection rates and NPIs. Two subsamples of persons with mental health problems were selected (people who reported being depressed, <italic>n</italic> = 9.240 or nervous/anxious, <italic>n</italic> = 10.551). Decline in mental health was assessed by asking whether depressive symptoms or nervousness/anxiety have become worse since the beginning of the COVID-19 outbreak. For each outcome, logistic regression models with survey-design were used to estimate odds ratios (OR), using social factors (age, gender, education, living alone, and personal contacts) and macro indicators (stringency of NPIs and infection rates) as predictors.</p>
</sec>
<sec>
<title>Results</title>
<p>Higher age was associated with a lower likelihood of becoming more depressed (OR 0.87) or nervous/anxious (OR 0.88), while female gender increased the odds of a decline in mental health (OR 1.53 for being more depressed; OR 1.57 for being more nervous/anxious). Higher education was only associated with becoming more nervous/anxious (OR 1.59), while living alone or rare personal contacts were not statistically significant. People from countries with higher infection rates were more likely to become more depressed (OR 3.31) or nervous/anxious (OR 4.12), while stringency of NPIs showed inconsistent associations.</p>
</sec>
<sec>
<title>Conclusion</title>
<p>A majority of European older adults showed a decline in mental health since the beginning of the COVID-19 outbreak. This is especially true in countries with high prevalence rates of COVID-19. Among older European adults, age seems to be a protective factor for a decline in mental health while female gender apparently is a risk factor. Moreover, although NPIs are an essential preventative mechanism to reduce the pandemic spread, they might influence the vulnerability for elderly people suffering from mental health problems.</p>
</sec></abstract>
<kwd-group>
<kwd>COVID-19</kwd>
<kwd>mental health</kwd>
<kwd>social factors</kwd>
<kwd>elder people</kwd>
<kwd>NPI</kwd>
<kwd>depression</kwd>
<kwd>anxiety</kwd>
</kwd-group>
<counts>
<fig-count count="0"/>
<table-count count="5"/>
<equation-count count="0"/>
<ref-count count="43"/>
<page-count count="10"/>
<word-count count="7126"/>
</counts>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="s1">
<title>Introduction</title>
<p>The new coronavirus infection (COVID-19), first discovered in December 2019 in Wuhan City, China, has spread worldwide. Accordingly, the World Health Organization (WHO) officially declared the outbreak as international public health emergency (<xref ref-type="bibr" rid="B1">1</xref>). COVID-19 is a severe respiratory infection with high infection rate and relatively high mortality, in particular when medication or vaccination was not available. Consequently, governments across the world have deployed a wide range of non-pharmaceutical interventions (NPIs) to mitigate the spread of COVID-19. The responses to COVID-19 in different countries varied from herd immunity strategies, which implied only few or almost no measures, to more assertive approaches based on the implementation of a wide range of stringent NPIs (<xref ref-type="bibr" rid="B2">2</xref>, <xref ref-type="bibr" rid="B3">3</xref>). The prevalence of COVID-19 affected the stringency of NPIs implemented in different countries. However, countries undertaking more strict measures were also able to contain the pandemic outbreak. Thus, there were both great variations in the stringency of government responses and infection rates of COVID-19 between countries worldwide (<xref ref-type="bibr" rid="B4">4</xref>, <xref ref-type="bibr" rid="B5">5</xref>).</p>
<p>One of the main goals of the various NPIs was to protect risk groups who are particularly vulnerable to COVID-19. Especially old age was highlighted early as a risk factor for adverse outcomes of a COVID-19 infection and is one of the most important determinants of mortality (<xref ref-type="bibr" rid="B6">6</xref>, <xref ref-type="bibr" rid="B7">7</xref>). Studies suggest that the odds of in-hospital deaths increase by a factor of 1.1 per year of age (<xref ref-type="bibr" rid="B8">8</xref>). The downside of certain NPIs, such as limiting social contacts, gathering restrictions, or short- and medium-term lockdowns, is an increased risk of negative consequences for mental health in the population. Again, especially the older population is a risk group that is prone to mental illnesses during the current pandemic (<xref ref-type="bibr" rid="B9">9</xref>, <xref ref-type="bibr" rid="B10">10</xref>).</p>
<p>Mental health is not only affected by limited social contacts and lockdowns. Rather, widespread occurrences of infectious diseases in general, and of COVID-19 in particular, are closely related to symptoms of psychological distress and affected mental health (<xref ref-type="bibr" rid="B11">11</xref>). In a survey among the Chinese population, 37.1% of the elderly had experienced depression and anxiety during the pandemic (<xref ref-type="bibr" rid="B12">12</xref>, <xref ref-type="bibr" rid="B13">13</xref>). Studies about previous experiences with outbreaks of infectious diseases also have found that the proportion of people who are mentally affected by a pandemic is higher than people who are physically infected. In this regard, depressive feelings, anxiety and fear were common adverse effects (<xref ref-type="bibr" rid="B14">14</xref>, <xref ref-type="bibr" rid="B15">15</xref>).</p>
<p>It is known that social factors such as social contacts and relationships, serve as protective buffers that lower the risk of morbidity and mortality (<xref ref-type="bibr" rid="B16">16</xref>). Furthermore, social networks have a positive impact on mental health (<xref ref-type="bibr" rid="B17">17</xref>). However, the psychological distress for the general population caused by the COVID-19 pandemic and its government response measures is not fully understood yet. International studies mostly focus on the mental health impact of infected quarantined patients and rarely on government response measures in general (<xref ref-type="bibr" rid="B18">18</xref>).</p>
<p>Against this background, this article addresses the following research questions: (1) What is the prevalence of a decline in mental health in different European countries during the COVID-19 pandemic? (2) What are the associations of social factors (gender, age, education, and social contacts) with a decline in mental health? (3) Do the associations vary according to infection rates and government response measures?</p>
</sec>
<sec sec-type="materials and methods" id="s2">
<title>Materials and Methods</title>
<sec>
<title>Sample and Participants</title>
<p>Analyses were based on data from the eighth wave of SHARE, the Survey of Health, Aging, and Retirement in Europe (<xref ref-type="bibr" rid="B19">19</xref>). SHARE is a large pan-European social science panel study. The first wave of data collection started in 2004, including 12 countries. New waves of data collection were repeated every 2&#x02013;3 years. Refresher samples were drawn to compensate for panel attrition. In total, about 530,000 interviews with people from 28 European countries and Israel were conducted. Topics covered in the interviews are, among others, social networks, physical and mental health, employment, retirement, financial situation, and social activities. The wave of 2020 was the first one that included data on the pandemic outbreak and was carried out in 27 countries. Based on population registers, SHARE used probability samples within the countries and includes non-institutionalized adults aged 50 years or older and, if available, their partners. Exclusion criteria were: being incarcerated, moved abroad, unable to speak the language of questionnaire, deceased, hospitalized, moved to an unknown address or not residing at sampled address (<xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B21">21</xref>). The outbreak of the COVID-19 pandemic hit the data collection in the middle of the 8th wave, thus fieldwork was suspended and a specific COVID-19 questionnaire was developed to collect data with pandemic related topics. The fieldwork for this survey started in June 2020 and ended in September 2020.</p>
<p>The final SHARE sample consisted of <italic>N</italic> = 46.500 participants from 27 countries. As we were interested in the decline of mental health, we only considered those respondents who previously reported being depressed and/or being nervous or anxious (see measures). Thus, for the present study, two subsamples of persons with mental health problems were selected (people who reported being depressed, <italic>n</italic> = 9.240 or nervous/anxious, <italic>n</italic> = 10.551).</p>
</sec>
<sec>
<title>Additional Data Sources</title>
<p>Additional data sources were used to build two macro indicators. The stringency in government response toward the COVID-19 outbreak was based on the Oxford COVID-19 Government Response Tracker (OxCGRT), a global panel database of pandemic policies that covered more than 180 countries (<xref ref-type="bibr" rid="B22">22</xref>). For each country at each day of the pandemic, measures to reduce the spread of the outbreak, like longer or stricter lockdown measures, reduced social contacts, and similar, were recorded and a daily index of government response for each country (stringency index) was calculated. Countries with higher stringency index have undertaken more intensive measures to reduce the spread of COVID-19. Data was filtered to include only those countries that were also present in this survey.</p>
<p>Data on numbers of confirmed cases of people infected with COVID-19 were taken from the COVID-19 Data Repository by the Center for Systems Science and Engineering (CSSE) at the Johns Hopkins University (<xref ref-type="bibr" rid="B23">23</xref>). Data on confirmed cases are collected from more than 190 countries. Based on these data, the percentage of the population infected with COVID-19 was calculated. Again, only data from countries that were also included in this survey was used.</p>
<p>Both data sources were continuously updated and thereby reflected the evolution of infection rates and government measures during the pandemic. To adequately represent the situation in the participants&#x00027; countries at the time of the SHARE fieldwork, only those data for government response and confirmed cases that referred to the period from the beginning of the COVID-19 outbreak until the time of field work in each SHARE country was used (i.e., summer 2020).</p>
</sec>
<sec>
<title>Measures</title>
<sec>
<title>Dependent Variables</title>
<p>Mental health problems were assessed by asking &#x0201C;In the last month, have you been sad or depressed?.&#x0201D; If answered yes, a person is considered as &#x0201C;depressed.&#x0201D; Similarly, people were considered as being nervous or anxious if they answered &#x0201C;yes&#x0201D; to the question &#x0201C;In the last month, have you felt nervous, anxious, or on edge?.&#x0201D; Decline in mental health was then assessed by asking those respondents who were depressed or nervous/anxious, whether that has &#x0201C;been more so, less so, or about the same as before the outbreak of Corona?.&#x0201D; The variable was dichotomized. The option &#x0201C;more so&#x0201D; was considered as decline in mental health, &#x0201C;less so&#x0201D; and &#x0201C;about the same&#x0201D; refers to no decline in mental health. Both mental health indicators were recoded this way.</p>
</sec>
<sec>
<title>Independent Variables</title>
<p>Social factors included in the regression models are respondent&#x00027;s age, gender, education, whether they lived alone in their household and personal contacts. Education was based on the International Standard Classification of Education (<xref ref-type="bibr" rid="B24">24</xref>), which ranges from 0 to 6 (low to higher education) and is recoded into three levels: &#x0201C;low (lower/upper secondary),&#x0201D; &#x0201C;mid (post-secondary),&#x0201D; and &#x0201C;high (tertiary).&#x0201D; Personal contacts describe the intensity of contacts that respondents had with family and friends from outside their home since the outbreak of COVID-19. The question was &#x0201C;Since the outbreak of Corona, how often did you have personal contact, that is, face to face, with the following people from outside your home? Was it daily, several times a week, about once a week, less often, or never?.&#x0201D; People were asked to respond to this question with regard to their (a) children, (b) parents, (c) other relatives, and (d) neighbors, friends, or colleagues. Rare personal contacts are present if the respondents had personal contacts less than once a week in relation to all of the four groups.</p>
<p>The stringency in government response toward the COVID-19 outbreak and the percentage of the population infected with COVID-19 were used as macro indicators in the regression models. For each country, the mean value for the daily Oxford stringency index values, from the start of the pandemic until the beginning of the fieldwork, was calculated. This variable represents the average government response within each country to the COVID-19 outbreak and has a possible range from 0 to 100 (<xref ref-type="bibr" rid="B22">22</xref>). Based on the distribution of this variable, an indicator was built, with countries being classified into three groups: low stringency (average Oxford stringency index &#x0003C;40), middle stringency (index between 40 and 45) and high stringency (index &#x0003E; 45). The proportion of the population infected with COVID-19, which was calculated based on the data from the COVID-19 Data Repository, refers to the cumulative percentage from the beginning of the pandemic until the start of the SHARE data collection in each country (i.e., summer 2020).</p>
</sec>
</sec>
<sec>
<title>Statistical Analysis</title>
<p>Descriptive statistics were used to document the sample characteristics. For each of the two dependent variables indicating decline in mental health, three logistic regression models for complex samples were calculated, using quasi-binomial links to properly account for survey-weighting, disproportional sampling, and selective mortality. The country variable was used to define the strata in the survey-design, hence the regression models accounted for the fact that respondents were clustered within different countries. Robust Horvitz-Thompson standard errors are reported (<xref ref-type="bibr" rid="B25">25</xref>). The first model only included social factors, the second model only included the two macro indicators, and the third (full) model included both social factors and macro indicators. Models were checked for the presence of multicollinearity. All models had a variance inflation factor (VIF) below 2.8, indicating no severe collinearity issues (<xref ref-type="bibr" rid="B26">26</xref>). All analyses were performed using the R statistical package (<xref ref-type="bibr" rid="B27">27</xref>), including the packages &#x0201C;survey&#x0201D; (<xref ref-type="bibr" rid="B28">28</xref>), &#x0201C;ggplot2&#x0201D; (<xref ref-type="bibr" rid="B29">29</xref>), and &#x0201C;parameters&#x0201D; (<xref ref-type="bibr" rid="B30">30</xref>).</p>
</sec>
</sec>
<sec sec-type="results" id="s3">
<title>Results</title>
<sec>
<title>Classification of Stringency and COVID Infection Rates</title>
<p>Each of the country classifications &#x0201C;low stringency,&#x0201D; &#x0201C;middle stringency,&#x0201D; and &#x0201C;high stringency&#x0201D; included nine countries (see <xref ref-type="table" rid="T1">Table 1</xref>). The average stringency index for low stringency countries varied from 34 to 39. Latvia, Slovenia and Bulgaria had rather low COVID-19 infection rates of 0.06, 0.07, and 0.08%, respectively. Countries with a middle stringency had a mean stringency index from 40 to 44. Overall, these countries showed the lowest COVID-19 infection rates from all three stringency classifications. High stringency countries had an average stringency index ranging from 45 to 56. The proportion of people infected with COVID-19 ranged from 0.11 to 0.60%, and overall, these countries had the highest infection rates.</p>
<table-wrap position="float" id="T1">
<label>Table 1</label>
<caption><p>Average stringency index (SI) and percentage of COVID infections in the population by country, based on data from the Oxford COVID-19 Government Response Tracker and the COVID-19 Data Repository from CSSE.</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th valign="top" align="center" colspan="3" style="border-bottom: thin solid #000000;"><bold>Low stringency countries (SI</bold> <bold>&#x0003C;</bold> <bold>40)</bold></th>
<th valign="top" align="center" colspan="3" style="border-bottom: thin solid #000000;"><bold>Middle stringency countries (SI 40&#x02013;45)</bold></th>
<th valign="top" align="center" colspan="3" style="border-bottom: thin solid #000000;"><bold>High stringency countries (SI</bold> <bold>&#x0003E;</bold> <bold>45)</bold></th>
</tr>
<tr>
<th valign="top" align="left"><bold>Country</bold></th>
<th valign="top" align="center"><bold>Average SI</bold></th>
<th valign="top" align="center"><bold>COVID infections, %</bold></th>
<th valign="top" align="left"><bold>Country</bold></th>
<th valign="top" align="center"><bold>Average SI</bold></th>
<th valign="top" align="center"><bold>COVID infections, %</bold></th>
<th valign="top" align="center"><bold>Country</bold></th>
<th valign="top" align="center"><bold>Average SI</bold></th>
<th valign="top" align="center"><bold>COVID infections, %</bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Bulgaria</td>
<td valign="top" align="center">38</td>
<td valign="top" align="center">0.08</td>
<td valign="top" align="left">Austria</td>
<td valign="top" align="center">41</td>
<td valign="top" align="center">0.22</td>
<td valign="top" align="center">Belgium</td>
<td valign="top" align="center">45</td>
<td valign="top" align="center">0.52</td>
</tr>
<tr>
<td valign="top" align="left">Denmark</td>
<td valign="top" align="center">39</td>
<td valign="top" align="center">0.21</td>
<td valign="top" align="left">Czech Republic</td>
<td valign="top" align="center">40</td>
<td valign="top" align="center">0.09</td>
<td valign="top" align="center">Croatia</td>
<td valign="top" align="center">47</td>
<td valign="top" align="center">0.60</td>
</tr>
<tr>
<td valign="top" align="left">Estonia</td>
<td valign="top" align="center">35</td>
<td valign="top" align="center">0.15</td>
<td valign="top" align="left">Germany</td>
<td valign="top" align="center">43</td>
<td valign="top" align="center">0.23</td>
<td valign="top" align="center">Cyprus</td>
<td valign="top" align="center">47</td>
<td valign="top" align="center">0.11</td>
</tr>
<tr>
<td valign="top" align="left">Finland</td>
<td valign="top" align="center">37</td>
<td valign="top" align="center">0.13</td>
<td valign="top" align="left">Greece</td>
<td valign="top" align="center">44</td>
<td valign="top" align="center">0.03</td>
<td valign="top" align="center">France</td>
<td valign="top" align="center">51</td>
<td valign="top" align="center">0.30</td>
</tr>
<tr>
<td valign="top" align="left">Latvia</td>
<td valign="top" align="center">38</td>
<td valign="top" align="center">0.06</td>
<td valign="top" align="left">Hungary</td>
<td valign="top" align="center">41</td>
<td valign="top" align="center">0.04</td>
<td valign="top" align="center">Israel</td>
<td valign="top" align="center">50</td>
<td valign="top" align="center">0.19</td>
</tr>
<tr>
<td valign="top" align="left">Luxembourg</td>
<td valign="top" align="center">38</td>
<td valign="top" align="center">0.66</td>
<td valign="top" align="left">Lithuania</td>
<td valign="top" align="center">43</td>
<td valign="top" align="center">0.06</td>
<td valign="top" align="center">Italy</td>
<td valign="top" align="center">56</td>
<td valign="top" align="center">0.39</td>
</tr>
<tr>
<td valign="top" align="left">Slovenia</td>
<td valign="top" align="center">39</td>
<td valign="top" align="center">0.07</td>
<td valign="top" align="left">Netherlands</td>
<td valign="top" align="center">43</td>
<td valign="top" align="center">0.29</td>
<td valign="top" align="center">Malta</td>
<td valign="top" align="center">47</td>
<td valign="top" align="center">0.12</td>
</tr>
<tr>
<td valign="top" align="left">Sweden</td>
<td valign="top" align="center">34</td>
<td valign="top" align="center">0.53</td>
<td valign="top" align="left">Poland</td>
<td valign="top" align="center">44</td>
<td valign="top" align="center">0.07</td>
<td valign="top" align="center">Romania</td>
<td valign="top" align="center">46</td>
<td valign="top" align="center">0.11</td>
</tr>
<tr>
<td valign="top" align="left">Bulgaria</td>
<td valign="top" align="center">38</td>
<td valign="top" align="center">0.36</td>
<td valign="top" align="left">Slovakia</td>
<td valign="top" align="center">42</td>
<td valign="top" align="center">0.03</td>
<td valign="top" align="center">Spain</td>
<td valign="top" align="center">47</td>
<td valign="top" align="center">0.52</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec>
<title>Sample Description</title>
<p>Characteristics of the subsample of respondents who reported to be depressed or sad (<italic>n</italic> = 9,240) is shown in <xref ref-type="table" rid="T2">Table 2</xref>. The mean age of respondents was 72.3 years. 19.3% had high education. 70.0% were female. 36.5% of the participants mentioned that they had rare personal contacts. A share of 32.3% were living alone. 63.0% reported that they felt more depressed since the beginning of COVID-19.</p>
<table-wrap position="float" id="T2">
<label>Table 2</label>
<caption><p>Sample description of respondents reporting depressive symptoms, SHARE data (8th wave), unweighted.</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th valign="top" align="left"><bold>Country</bold></th>
<th valign="top" align="center"><bold><italic>N</italic></bold></th>
<th valign="top" align="center"><bold>Mean age (SD)</bold></th>
<th valign="top" align="center"><bold>High education, %</bold></th>
<th valign="top" align="center"><bold>Female gender, %</bold></th>
<th valign="top" align="center"><bold>Rare personal contacts, %</bold></th>
<th valign="top" align="center"><bold>Living alone, %</bold></th>
<th valign="top" align="center"><bold>More depressed, %</bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" colspan="8"><bold>Low stringency countries (SI</bold> <bold>&#x0003C;</bold> <bold>40)</bold></td>
</tr>
<tr>
<td valign="top" align="left">Bulgaria</td>
<td valign="top" align="center">174</td>
<td valign="top" align="center">71.2 (9.1)</td>
<td valign="top" align="center">14.9</td>
<td valign="top" align="center">69.0</td>
<td valign="top" align="center">20.8</td>
<td valign="top" align="center">35.1</td>
<td valign="top" align="center">58.0</td>
</tr>
<tr>
<td valign="top" align="left">Denmark</td>
<td valign="top" align="center">203</td>
<td valign="top" align="center">71.7 (9.5)</td>
<td valign="top" align="center">42.3</td>
<td valign="top" align="center">70.9</td>
<td valign="top" align="center">33.0</td>
<td valign="top" align="center">37.4</td>
<td valign="top" align="center">62.6</td>
</tr>
<tr>
<td valign="top" align="left">Estonia</td>
<td valign="top" align="center">691</td>
<td valign="top" align="center">74.6 (9.7)</td>
<td valign="top" align="center">21.4</td>
<td valign="top" align="center">74.4</td>
<td valign="top" align="center">42.2</td>
<td valign="top" align="center">43.7</td>
<td valign="top" align="center">61.2</td>
</tr>
<tr>
<td valign="top" align="left">Finland</td>
<td valign="top" align="center">210</td>
<td valign="top" align="center">71.1 (9.7)</td>
<td valign="top" align="center">35.7</td>
<td valign="top" align="center">69.0</td>
<td valign="top" align="center">39.8</td>
<td valign="top" align="center">26.2</td>
<td valign="top" align="center">59.5</td>
</tr>
<tr>
<td valign="top" align="left">Latvia</td>
<td valign="top" align="center">137</td>
<td valign="top" align="center">71.6 (9.8)</td>
<td valign="top" align="center">24.8</td>
<td valign="top" align="center">73.0</td>
<td valign="top" align="center">45.9</td>
<td valign="top" align="center">47.4</td>
<td valign="top" align="center">45.3</td>
</tr>
<tr>
<td valign="top" align="left">Luxembourg</td>
<td valign="top" align="center">208</td>
<td valign="top" align="center">70.2 (8.5)</td>
<td valign="top" align="center">17.5</td>
<td valign="top" align="center">66.3</td>
<td valign="top" align="center">45.2</td>
<td valign="top" align="center">22.6</td>
<td valign="top" align="center">72.1</td>
</tr>
<tr>
<td valign="top" align="left">Slovenia</td>
<td valign="top" align="center">412</td>
<td valign="top" align="center">73.6 (9.3)</td>
<td valign="top" align="center">13.6</td>
<td valign="top" align="center">70.6</td>
<td valign="top" align="center">34.5</td>
<td valign="top" align="center">26.2</td>
<td valign="top" align="center">52.4</td>
</tr>
<tr>
<td valign="top" align="left">Sweden</td>
<td valign="top" align="center">221</td>
<td valign="top" align="center">75.8 (8.0)</td>
<td valign="top" align="center">38.2</td>
<td valign="top" align="center">65.6</td>
<td valign="top" align="center">25.7</td>
<td valign="top" align="center">41.6</td>
<td valign="top" align="center">69.7</td>
</tr>
<tr>
<td valign="top" align="left">Switzerland</td>
<td valign="top" align="center">326</td>
<td valign="top" align="center">73.5 (9.4)</td>
<td valign="top" align="center">17.8</td>
<td valign="top" align="center">70.9</td>
<td valign="top" align="center">46.6</td>
<td valign="top" align="center">38.3</td>
<td valign="top" align="center">70.6</td>
</tr>
<tr>
<td valign="top" align="left">Total</td>
<td valign="top" align="center">2,582</td>
<td valign="top" align="center">73.1 (9.4)</td>
<td valign="top" align="center">23.3</td>
<td valign="top" align="center">70.8</td>
<td valign="top" align="center">38.2</td>
<td valign="top" align="center">36.1</td>
<td valign="top" align="center">61.5</td>
</tr>
<tr>
<td valign="top" align="left" colspan="8"><bold>Middle stringency countries (SI 40&#x02013;45)</bold></td>
</tr>
<tr>
<td valign="top" align="left">Austria</td>
<td valign="top" align="center">316</td>
<td valign="top" align="center">75.3 (9.2)</td>
<td valign="top" align="center">26.0</td>
<td valign="top" align="center">73.1</td>
<td valign="top" align="center">33.5</td>
<td valign="top" align="center">42.4</td>
<td valign="top" align="center">52.8</td>
</tr>
<tr>
<td valign="top" align="left">Czech Republic</td>
<td valign="top" align="center">418</td>
<td valign="top" align="center">73.4 (8.0)</td>
<td valign="top" align="center">12.9</td>
<td valign="top" align="center">76.1</td>
<td valign="top" align="center">30.7</td>
<td valign="top" align="center">39.7</td>
<td valign="top" align="center">50.5</td>
</tr>
<tr>
<td valign="top" align="left">Germany</td>
<td valign="top" align="center">626</td>
<td valign="top" align="center">71.4 (9.5)</td>
<td valign="top" align="center">30.9</td>
<td valign="top" align="center">66.0</td>
<td valign="top" align="center">29.9</td>
<td valign="top" align="center">33.5</td>
<td valign="top" align="center">53.2</td>
</tr>
<tr>
<td valign="top" align="left">Greece</td>
<td valign="top" align="center">719</td>
<td valign="top" align="center">72.2 (10.1)</td>
<td valign="top" align="center">13.8</td>
<td valign="top" align="center">68.3</td>
<td valign="top" align="center">30.6</td>
<td valign="top" align="center">34.4</td>
<td valign="top" align="center">74.0</td>
</tr>
<tr>
<td valign="top" align="left">Hungary</td>
<td valign="top" align="center">167</td>
<td valign="top" align="center">72.2 (7.6)</td>
<td valign="top" align="center">17.2</td>
<td valign="top" align="center">70.7</td>
<td valign="top" align="center">26.9</td>
<td valign="top" align="center">39.5</td>
<td valign="top" align="center">41.9</td>
</tr>
<tr>
<td valign="top" align="left">Lithuania</td>
<td valign="top" align="center">327</td>
<td valign="top" align="center">71.9 (10.3)</td>
<td valign="top" align="center">33.6</td>
<td valign="top" align="center">70.6</td>
<td valign="top" align="center">50.8</td>
<td valign="top" align="center">36.4</td>
<td valign="top" align="center">63.0</td>
</tr>
<tr>
<td valign="top" align="left">Netherlands</td>
<td valign="top" align="center">108</td>
<td valign="top" align="center">72.4 (9.1)</td>
<td valign="top" align="center">36.7</td>
<td valign="top" align="center">74.1</td>
<td valign="top" align="center">37.4</td>
<td valign="top" align="center">49.1</td>
<td valign="top" align="center">71.3</td>
</tr>
<tr>
<td valign="top" align="left">Poland</td>
<td valign="top" align="center">613</td>
<td valign="top" align="center">69.4 (9.4)</td>
<td valign="top" align="center">11.9</td>
<td valign="top" align="center">67.2</td>
<td valign="top" align="center">34.0</td>
<td valign="top" align="center">21.7</td>
<td valign="top" align="center">42.6</td>
</tr>
<tr>
<td valign="top" align="left">Slovakia</td>
<td valign="top" align="center">192</td>
<td valign="top" align="center">66.3 (8.6)</td>
<td valign="top" align="center">5.2</td>
<td valign="top" align="center">64.1</td>
<td valign="top" align="center">35.1</td>
<td valign="top" align="center">22.9</td>
<td valign="top" align="center">49.5</td>
</tr>
<tr>
<td valign="top" align="left">Total</td>
<td valign="top" align="center">3,486</td>
<td valign="top" align="center">71.6 (9.5)</td>
<td valign="top" align="center">19.8</td>
<td valign="top" align="center">69.3</td>
<td valign="top" align="center">33.5</td>
<td valign="top" align="center">33.6</td>
<td valign="top" align="center">56.0</td>
</tr>
<tr>
<td valign="top" align="left" colspan="8"><bold>High stringency countries (SI</bold> <bold>&#x0003E;</bold> <bold>45)</bold></td>
</tr>
<tr>
<td valign="top" align="left">Belgium</td>
<td valign="top" align="center">439</td>
<td valign="top" align="center">71.2 (9.6)</td>
<td valign="top" align="center">35.3</td>
<td valign="top" align="center">72.0</td>
<td valign="top" align="center">36.2</td>
<td valign="top" align="center">40.8</td>
<td valign="top" align="center">82.5</td>
</tr>
<tr>
<td valign="top" align="left">Croatia</td>
<td valign="top" align="center">296</td>
<td valign="top" align="center">71.0 (8.9)</td>
<td valign="top" align="center">11.1</td>
<td valign="top" align="center">67.2</td>
<td valign="top" align="center">28.6</td>
<td valign="top" align="center">24.3</td>
<td valign="top" align="center">56.4</td>
</tr>
<tr>
<td valign="top" align="left">Cyprus</td>
<td valign="top" align="center">92</td>
<td valign="top" align="center">75.0 (9.6)</td>
<td valign="top" align="center">7.6</td>
<td valign="top" align="center">79.3</td>
<td valign="top" align="center">56.0</td>
<td valign="top" align="center">37.0</td>
<td valign="top" align="center">69.6</td>
</tr>
<tr>
<td valign="top" align="left">France</td>
<td valign="top" align="center">529</td>
<td valign="top" align="center">73.7 (9.8)</td>
<td valign="top" align="center">28.2</td>
<td valign="top" align="center">73.9</td>
<td valign="top" align="center">34.9</td>
<td valign="top" align="center">41.2</td>
<td valign="top" align="center">67.5</td>
</tr>
<tr>
<td valign="top" align="left">Israel</td>
<td valign="top" align="center">164</td>
<td valign="top" align="center">74.6 (8.8)</td>
<td valign="top" align="center">26.4</td>
<td valign="top" align="center">68.9</td>
<td valign="top" align="center">41.5</td>
<td valign="top" align="center">34.8</td>
<td valign="top" align="center">73.2</td>
</tr>
<tr>
<td valign="top" align="left">Italy</td>
<td valign="top" align="center">722</td>
<td valign="top" align="center">72.2 (9.5)</td>
<td valign="top" align="center">7.2</td>
<td valign="top" align="center">68.1</td>
<td valign="top" align="center">39.6</td>
<td valign="top" align="center">19.3</td>
<td valign="top" align="center">77.0</td>
</tr>
<tr>
<td valign="top" align="left">Malta</td>
<td valign="top" align="center">212</td>
<td valign="top" align="center">70.5 (8.9)</td>
<td valign="top" align="center">2.8</td>
<td valign="top" align="center">66.5</td>
<td valign="top" align="center">69.8</td>
<td valign="top" align="center">17.9</td>
<td valign="top" align="center">78.8</td>
</tr>
<tr>
<td valign="top" align="left">Romania</td>
<td valign="top" align="center">326</td>
<td valign="top" align="center">69.9 (9.6)</td>
<td valign="top" align="center">3.4</td>
<td valign="top" align="center">69.3</td>
<td valign="top" align="center">42.9</td>
<td valign="top" align="center">21.5</td>
<td valign="top" align="center">58.6</td>
</tr>
<tr>
<td valign="top" align="left">Spain</td>
<td valign="top" align="center">392</td>
<td valign="top" align="center">75.2 (9.0)</td>
<td valign="top" align="center">9.9</td>
<td valign="top" align="center">70.4</td>
<td valign="top" align="center">23.7</td>
<td valign="top" align="center">19.6</td>
<td valign="top" align="center">76.0</td>
</tr>
<tr>
<td valign="top" align="left">Total</td>
<td valign="top" align="center">3,172</td>
<td valign="top" align="center">72.4 (9.5)</td>
<td valign="top" align="center">15.6</td>
<td valign="top" align="center">70.2</td>
<td valign="top" align="center">38.3</td>
<td valign="top" align="center">27.9</td>
<td valign="top" align="center">71.9</td>
</tr>
<tr>
<td valign="top" align="left" colspan="8"><bold>All countries</bold></td>
</tr>
<tr>
<td valign="top" align="left">Total</td>
<td valign="top" align="center">9,240</td>
<td valign="top" align="center">72.3 (9.5)</td>
<td valign="top" align="center">19.3</td>
<td valign="top" align="center">70.0</td>
<td valign="top" align="center">36.5</td>
<td valign="top" align="center">32.3</td>
<td valign="top" align="center">63.0</td>
</tr>
</tbody>
</table>
</table-wrap>
<p><xref ref-type="table" rid="T3">Table 3</xref> shows the characteristics of people who reported to be nervous and/or anxious. Their average age was 71.3 years. 37.9% were higher educated and 67.1% were of female gender. Rare personal contacts were reported by 37.8% of the respondents. 26.5% were living alone. 71.6% mentioned being more nervous and/or anxious since the pandemic outbreak.</p>
<table-wrap position="float" id="T3">
<label>Table 3</label>
<caption><p>Sample description of respondents reporting being nervous and/or anxious, SHARE data (8th wave), unweighted.</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th valign="top" align="left"><bold>Country</bold></th>
<th valign="top" align="center"><bold><italic>N</italic></bold></th>
<th valign="top" align="center"><bold>Mean age (SD)</bold></th>
<th valign="top" align="center"><bold>High education, %</bold></th>
<th valign="top" align="center"><bold>Female gender, %</bold></th>
<th valign="top" align="center"><bold>Rare personal contacts, %</bold></th>
<th valign="top" align="center"><bold>Living alone, %</bold></th>
<th valign="top" align="center"><bold>More nervous/anxious, %</bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" colspan="8"><bold>Low stringency countries (SI</bold> <bold>&#x0003C;</bold> <bold>40)</bold></td>
</tr>
<tr>
<td valign="top" align="left">Bulgaria</td>
<td valign="top" align="center">241</td>
<td valign="top" align="center">70.5 (9.3)</td>
<td valign="top" align="center">14.1</td>
<td valign="top" align="center">63.9</td>
<td valign="top" align="center">20.4</td>
<td valign="top" align="center">29.0</td>
<td valign="top" align="center">53.1</td>
</tr>
<tr>
<td valign="top" align="left">Denmark</td>
<td valign="top" align="center">398</td>
<td valign="top" align="center">69.5 (8.7)</td>
<td valign="top" align="center">49.4</td>
<td valign="top" align="center">65.6</td>
<td valign="top" align="center">41.5</td>
<td valign="top" align="center">24.4</td>
<td valign="top" align="center">81.4</td>
</tr>
<tr>
<td valign="top" align="left">Estonia</td>
<td valign="top" align="center">813</td>
<td valign="top" align="center">72.6 (9.2)</td>
<td valign="top" align="center">23.6</td>
<td valign="top" align="center">69.6</td>
<td valign="top" align="center">42.2</td>
<td valign="top" align="center">35.2</td>
<td valign="top" align="center">69.6</td>
</tr>
<tr>
<td valign="top" align="left">Finland</td>
<td valign="top" align="center">268</td>
<td valign="top" align="center">69.3 (9.0)</td>
<td valign="top" align="center">47.4</td>
<td valign="top" align="center">64.6</td>
<td valign="top" align="center">37.1</td>
<td valign="top" align="center">23.9</td>
<td valign="top" align="center">60.4</td>
</tr>
<tr>
<td valign="top" align="left">Latvia</td>
<td valign="top" align="center">215</td>
<td valign="top" align="center">70.5 (9.5)</td>
<td valign="top" align="center">22.3</td>
<td valign="top" align="center">73.0</td>
<td valign="top" align="center">45.5</td>
<td valign="top" align="center">34.9</td>
<td valign="top" align="center">67.4</td>
</tr>
<tr>
<td valign="top" align="left">Luxembourg</td>
<td valign="top" align="center">239</td>
<td valign="top" align="center">68.8 (8.0)</td>
<td valign="top" align="center">18.3</td>
<td valign="top" align="center">62.8</td>
<td valign="top" align="center">43.5</td>
<td valign="top" align="center">20.1</td>
<td valign="top" align="center">80.3</td>
</tr>
<tr>
<td valign="top" align="left">Slovenia</td>
<td valign="top" align="center">529</td>
<td valign="top" align="center">72.4 (9.3)</td>
<td valign="top" align="center">17.0</td>
<td valign="top" align="center">69.9</td>
<td valign="top" align="center">38.4</td>
<td valign="top" align="center">23.4</td>
<td valign="top" align="center">66.0</td>
</tr>
<tr>
<td valign="top" align="left">Sweden</td>
<td valign="top" align="center">267</td>
<td valign="top" align="center">74.0 (8.5)</td>
<td valign="top" align="center">42.5</td>
<td valign="top" align="center">67.0</td>
<td valign="top" align="center">25.9</td>
<td valign="top" align="center">36.7</td>
<td valign="top" align="center">76.4</td>
</tr>
<tr>
<td valign="top" align="left">Switzerland</td>
<td valign="top" align="center">302</td>
<td valign="top" align="center">72.1 (9.0)</td>
<td valign="top" align="center">18.9</td>
<td valign="top" align="center">71.5</td>
<td valign="top" align="center">51.0</td>
<td valign="top" align="center">30.5</td>
<td valign="top" align="center">80.5</td>
</tr>
<tr>
<td valign="top" align="left">Total</td>
<td valign="top" align="center">3,272</td>
<td valign="top" align="center">71.4 (9.1)</td>
<td valign="top" align="center">27.6</td>
<td valign="top" align="center">68.0</td>
<td valign="top" align="center">39.3</td>
<td valign="top" align="center">29.2</td>
<td valign="top" align="center">70.7</td>
</tr>
<tr>
<td valign="top" align="left" colspan="8"><bold>Middle stringency countries (SI 40-45)</bold></td>
</tr>
<tr>
<td valign="top" align="left">Austria</td>
<td valign="top" align="center">285</td>
<td valign="top" align="center">74.3 (9.1)</td>
<td valign="top" align="center">22.6</td>
<td valign="top" align="center">69.5</td>
<td valign="top" align="center">34.0</td>
<td valign="top" align="center">31.2</td>
<td valign="top" align="center">67.4</td>
</tr>
<tr>
<td valign="top" align="left">Czech Republic</td>
<td valign="top" align="center">432</td>
<td valign="top" align="center">73.2 (7.9)</td>
<td valign="top" align="center">14.7</td>
<td valign="top" align="center">75.2</td>
<td valign="top" align="center">29.6</td>
<td valign="top" align="center">34.5</td>
<td valign="top" align="center">66.9</td>
</tr>
<tr>
<td valign="top" align="left">Germany</td>
<td valign="top" align="center">531</td>
<td valign="top" align="center">69.9 (9.2)</td>
<td valign="top" align="center">32.6</td>
<td valign="top" align="center">65.5</td>
<td valign="top" align="center">31.5</td>
<td valign="top" align="center">26.7</td>
<td valign="top" align="center">71.8</td>
</tr>
<tr>
<td valign="top" align="left">Greece</td>
<td valign="top" align="center">992</td>
<td valign="top" align="center">71.6 (10.0)</td>
<td valign="top" align="center">17.5</td>
<td valign="top" align="center">64.7</td>
<td valign="top" align="center">37.0</td>
<td valign="top" align="center">28.3</td>
<td valign="top" align="center">83.3</td>
</tr>
<tr>
<td valign="top" align="left">Hungary</td>
<td valign="top" align="center">169</td>
<td valign="top" align="center">71.6 (7.2)</td>
<td valign="top" align="center">17.6</td>
<td valign="top" align="center">67.5</td>
<td valign="top" align="center">29.2</td>
<td valign="top" align="center">31.4</td>
<td valign="top" align="center">45.6</td>
</tr>
<tr>
<td valign="top" align="left">Lithuania</td>
<td valign="top" align="center">413</td>
<td valign="top" align="center">70.3 (10.3)</td>
<td valign="top" align="center">34.4</td>
<td valign="top" align="center">71.4</td>
<td valign="top" align="center">51.1</td>
<td valign="top" align="center">32.0</td>
<td valign="top" align="center">74.3</td>
</tr>
<tr>
<td valign="top" align="left">Netherlands</td>
<td valign="top" align="center">104</td>
<td valign="top" align="center">71.9 (8.7)</td>
<td valign="top" align="center">23.3</td>
<td valign="top" align="center">71.2</td>
<td valign="top" align="center">35.6</td>
<td valign="top" align="center">31.7</td>
<td valign="top" align="center">86.5</td>
</tr>
<tr>
<td valign="top" align="left">Poland</td>
<td valign="top" align="center">509</td>
<td valign="top" align="center">69.0 (9.1)</td>
<td valign="top" align="center">12.2</td>
<td valign="top" align="center">63.5</td>
<td valign="top" align="center">36.8</td>
<td valign="top" align="center">16.5</td>
<td valign="top" align="center">49.7</td>
</tr>
<tr>
<td valign="top" align="left">Slovakia</td>
<td valign="top" align="center">182</td>
<td valign="top" align="center">64.7 (8.2)</td>
<td valign="top" align="center">6.0</td>
<td valign="top" align="center">56.6</td>
<td valign="top" align="center">32.4</td>
<td valign="top" align="center">15.9</td>
<td valign="top" align="center">55.5</td>
</tr>
<tr>
<td valign="top" align="left">Total</td>
<td valign="top" align="center">3,617</td>
<td valign="top" align="center">70.9 (9.5)</td>
<td valign="top" align="center">20.6</td>
<td valign="top" align="center">67.0</td>
<td valign="top" align="center">36.0</td>
<td valign="top" align="center">27.4</td>
<td valign="top" align="center">69.6</td>
</tr>
<tr>
<td valign="top" align="left" colspan="8"><bold>High stringency countries (SI</bold> <bold>&#x0003E;</bold> <bold>45)</bold></td>
</tr>
<tr>
<td valign="top" align="left">Belgium</td>
<td valign="top" align="center">536</td>
<td valign="top" align="center">70.5 (9.6)</td>
<td valign="top" align="center">36.1</td>
<td valign="top" align="center">67.9</td>
<td valign="top" align="center">36.6</td>
<td valign="top" align="center">36.0</td>
<td valign="top" align="center">84.1</td>
</tr>
<tr>
<td valign="top" align="left">Croatia</td>
<td valign="top" align="center">342</td>
<td valign="top" align="center">70.0 (8.5)</td>
<td valign="top" align="center">15.3</td>
<td valign="top" align="center">63.5</td>
<td valign="top" align="center">32.1</td>
<td valign="top" align="center">19.0</td>
<td valign="top" align="center">64.3</td>
</tr>
<tr>
<td valign="top" align="left">Cyprus</td>
<td valign="top" align="center">109</td>
<td valign="top" align="center">73.1 (9.7)</td>
<td valign="top" align="center">12.8</td>
<td valign="top" align="center">75.2</td>
<td valign="top" align="center">54.6</td>
<td valign="top" align="center">26.6</td>
<td valign="top" align="center">65.1</td>
</tr>
<tr>
<td valign="top" align="left">France</td>
<td valign="top" align="center">575</td>
<td valign="top" align="center">72.7 (9.6)</td>
<td valign="top" align="center">25.9</td>
<td valign="top" align="center">72.7</td>
<td valign="top" align="center">33.3</td>
<td valign="top" align="center">36.3</td>
<td valign="top" align="center">73.6</td>
</tr>
<tr>
<td valign="top" align="left">Israel</td>
<td valign="top" align="center">213</td>
<td valign="top" align="center">74.4 (8.6)</td>
<td valign="top" align="center">29.1</td>
<td valign="top" align="center">70.4</td>
<td valign="top" align="center">39.8</td>
<td valign="top" align="center">28.2</td>
<td valign="top" align="center">72.3</td>
</tr>
<tr>
<td valign="top" align="left">Italy</td>
<td valign="top" align="center">767</td>
<td valign="top" align="center">71.1 (9.5)</td>
<td valign="top" align="center">6.6</td>
<td valign="top" align="center">61.8</td>
<td valign="top" align="center">39.3</td>
<td valign="top" align="center">14.6</td>
<td valign="top" align="center">77.7</td>
</tr>
<tr>
<td valign="top" align="left">Malta</td>
<td valign="top" align="center">332</td>
<td valign="top" align="center">69.2 (8.7)</td>
<td valign="top" align="center">4.5</td>
<td valign="top" align="center">63.0</td>
<td valign="top" align="center">64.8</td>
<td valign="top" align="center">14.8</td>
<td valign="top" align="center">78.0</td>
</tr>
<tr>
<td valign="top" align="left">Romania</td>
<td valign="top" align="center">347</td>
<td valign="top" align="center">68.3 (8.9)</td>
<td valign="top" align="center">2.3</td>
<td valign="top" align="center">61.1</td>
<td valign="top" align="center">39.8</td>
<td valign="top" align="center">15.3</td>
<td valign="top" align="center">61.4</td>
</tr>
<tr>
<td valign="top" align="left">Spain</td>
<td valign="top" align="center">441</td>
<td valign="top" align="center">75.3 (8.9)</td>
<td valign="top" align="center">9.5</td>
<td valign="top" align="center">69.6</td>
<td valign="top" align="center">24.0</td>
<td valign="top" align="center">18.6</td>
<td valign="top" align="center">77.3</td>
</tr>
<tr>
<td valign="top" align="left">Total</td>
<td valign="top" align="center">3,662</td>
<td valign="top" align="center">71.5 (9.4)</td>
<td valign="top" align="center">15.9</td>
<td valign="top" align="center">66.4</td>
<td valign="top" align="center">38.3</td>
<td valign="top" align="center">23.3</td>
<td valign="top" align="center">74.5</td>
</tr>
<tr>
<td valign="top" align="left" colspan="8"><bold>All countries</bold></td>
</tr>
<tr>
<td valign="top" align="left">Total</td>
<td valign="top" align="center">10,551</td>
<td valign="top" align="center">71.3 (9.4)</td>
<td valign="top" align="center">37.9</td>
<td valign="top" align="center">67.1</td>
<td valign="top" align="center">37.8</td>
<td valign="top" align="center">26.5</td>
<td valign="top" align="center">71.6</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec>
<title>Factors Associated With Feeling More Depressed Since the COVID-19 Outbreak</title>
<p>Looking at the regression model with social factors included as predictors (model 1, see <xref ref-type="table" rid="T4">Table 4</xref>), higher age was associated with a lower likelihood of becoming more depressed (OR 0.87). Female respondents were more likely to feel more depressed since the outbreak (OR 1.50). Middle or higher educated persons, compared to people with low educational level, were less likely to feel more depressed (OR 0.61), although only middle education was statistically significant. People who lived alone in their household had a lower chance of feeling more depressed (OR 0.79). Rare personal contacts were not significantly associated with feeling more depressed. Regarding the model with macro indicators (model 2), in comparison to countries with low stringency index, respondents from countries with middle stringency index were less likely to feel more depressive after the COVID-19 outbreak (OR 0.66). The likelihood of feeling more depressed for people from countries with high stringency index, however, was higher in comparison to the low stringency countries (OR 1.37). An increased rate of people infected with COVID-19 was also associated with a higher chance of feeling more depressed (OR 3.24). In the full model (model 3), in which both social factors and macro indicators were included, most associations remained very similar compared to the first two models. The most noticeable change was related to the association with education, which has diminished in model 3.</p>
<table-wrap position="float" id="T4">
<label>Table 4</label>
<caption><p>Feeling more depressed since pandemic outbreak, survey-weighted logistic regression models, showing odds ratios (OR), 95% confidence intervals (CI), and significances (<italic>p</italic>).</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th valign="top" align="left"><bold>Predictors</bold></th>
<th valign="top" align="center" colspan="3" style="border-bottom: thin solid #000000;"><bold>Model 1</bold></th>
<th valign="top" align="center" colspan="3" style="border-bottom: thin solid #000000;"><bold>Model 2</bold></th>
<th valign="top" align="center" colspan="3" style="border-bottom: thin solid #000000;"><bold>Model 3</bold></th>
</tr>
<tr>
<th/>
<th valign="top" align="center"><bold>OR</bold></th>
<th valign="top" align="center"><bold>CI</bold></th>
<th valign="top" align="center"><bold><italic>P</italic></bold></th>
<th valign="top" align="center"><bold>OR</bold></th>
<th valign="top" align="center"><bold>CI</bold></th>
<th valign="top" align="center"><bold><italic>P</italic></bold></th>
<th valign="top" align="center"><bold>OR</bold></th>
<th valign="top" align="center"><bold>CI</bold></th>
<th valign="top" align="center"><bold><italic>P</italic></bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Age</td>
<td valign="top" align="center">0.87</td>
<td valign="top" align="center">0.78&#x02013;0.97</td>
<td valign="top" align="center">0.011</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">0.87</td>
<td valign="top" align="center">0.78&#x02013;0.97</td>
<td valign="top" align="center">0.012</td>
</tr>
<tr>
<td valign="top" align="left">Female gender</td>
<td valign="top" align="center">1.50</td>
<td valign="top" align="center">1.16&#x02013;1.95</td>
<td valign="top" align="center">0.002</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.53</td>
<td valign="top" align="center">1.17&#x02013;1.99</td>
<td valign="top" align="center">0.002</td>
</tr>
<tr>
<td valign="top" align="left">Education: low (ref.)</td>
<td valign="top" align="center">1.00</td>
<td valign="top" align="center">&#x02013;</td>
<td valign="top" align="center">&#x02013;</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.00</td>
<td valign="top" align="center">&#x02013;</td>
<td valign="top" align="center">&#x02013;</td>
</tr>
<tr>
<td valign="top" align="left">Education: middle</td>
<td valign="top" align="center">0.61</td>
<td valign="top" align="center">0.46&#x02013;0.81</td>
<td valign="top" align="center">0.001</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">0.96</td>
<td valign="top" align="center">0.73&#x02013;1.26</td>
<td valign="top" align="center">0.750</td>
</tr>
<tr>
<td valign="top" align="left">Education: high</td>
<td valign="top" align="center">0.73</td>
<td valign="top" align="center">0.52&#x02013;1.01</td>
<td valign="top" align="center">0.058</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.01</td>
<td valign="top" align="center">0.72&#x02013;1.41</td>
<td valign="top" align="center">0.973</td>
</tr>
<tr>
<td valign="top" align="left">Living alone</td>
<td valign="top" align="center">0.79</td>
<td valign="top" align="center">0.64&#x02013;0.98</td>
<td valign="top" align="center">0.033</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">0.84</td>
<td valign="top" align="center">0.69&#x02013;1.03</td>
<td valign="top" align="center">0.094</td>
</tr>
<tr>
<td valign="top" align="left">Rare personal contacts</td>
<td valign="top" align="center">1.06</td>
<td valign="top" align="center">0.82&#x02013;1.37</td>
<td valign="top" align="center">0.640</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">0.96</td>
<td valign="top" align="center">0.73&#x02013;1.27</td>
<td valign="top" align="center">0.796</td>
</tr>
<tr>
<td valign="top" align="left">SI: low (ref.)</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.00</td>
<td valign="top" align="center">&#x02013;</td>
<td valign="top" align="center">&#x02013;</td>
<td valign="top" align="center">1.00</td>
<td valign="top" align="center">&#x02013;</td>
<td valign="top" align="center">&#x02013;</td>
</tr>
<tr>
<td valign="top" align="left">SI: middle<xref ref-type="table-fn" rid="TN1"><sup>a</sup></xref></td>
<td/>
<td/>
<td/>
<td valign="top" align="center">0.66</td>
<td valign="top" align="center">0.53&#x02013;0.82</td>
<td valign="top" align="center">&#x0003C;0.001</td>
<td valign="top" align="center">0.64</td>
<td valign="top" align="center">0.51&#x02013;0.79</td>
<td valign="top" align="center">&#x0003C;0.001</td>
</tr>
<tr>
<td valign="top" align="left">SI: high<xref ref-type="table-fn" rid="TN2"><sup>b</sup></xref></td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.37</td>
<td valign="top" align="center">1.10&#x02013;1.71</td>
<td valign="top" align="center">0.005</td>
<td valign="top" align="center">1.32</td>
<td valign="top" align="center">1.05&#x02013;1.66</td>
<td valign="top" align="center">0.019</td>
</tr>
<tr>
<td valign="top" align="left">% COVID-19 cases</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">3.24</td>
<td valign="top" align="center">1.61&#x02013;6.49</td>
<td valign="top" align="center">0.001</td>
<td valign="top" align="center">3.31</td>
<td valign="top" align="center">1.66&#x02013;6.59</td>
<td valign="top" align="center">0.001</td>
</tr>
<tr>
<td valign="top" align="left">Observations</td>
<td valign="top" align="center" colspan="3">9,017</td>
<td valign="top" align="center" colspan="3">9,017</td>
<td valign="top" align="center" colspan="3">9,017</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="TN1">
<label>a</label>
<p><italic>Middle stringency countries (reference: low stringency countries)</italic>.</p></fn>
<fn id="TN2">
<label>b</label>
<p><italic>High stringency countries (reference: low stringency countries)</italic>.</p></fn>
</table-wrap-foot>
</table-wrap>
</sec>
<sec>
<title>Factors Associated With Feeling More Nervous and/or Anxious Since the COVID-19 Outbreak</title>
<p>In model 1 (see <xref ref-type="table" rid="T5">Table 5</xref>), feeling more nervous/anxious was less likely when respondents were older (OR 0.87). Female gender was associated with a higher likelihood of feeling more nervous/anxious (OR 1.54). The probability of feeling more nervous/anxious is higher for people with high education as compared to people with low education (OR 1.34). No statistically significant associations were found for middle education (OR 1.08), living alone (OR 0.99), and rare personal contacts (OR 1.07). While the stringency index was not significantly associated with feeling more nervous/anxious (model 2), the rate of people infected with COVID-19 significantly increased the chance of feeling more nervous/anxious (OR 3.95). In model 3, most associations remained similar compared to the first two models, with an exception for education. The likelihood of feeling more nervous/anxious increased with medium and higher education.</p>
<table-wrap position="float" id="T5">
<label>Table 5</label>
<caption><p>Feeling more nervous/anxious since pandemic outbreak, survey-weighted logistic regression models, showing odds ratios (OR), 95% confidence intervals (CI), and significances (<italic>p</italic>).</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th valign="top" align="left"><bold>Predictors</bold></th>
<th valign="top" align="center" colspan="3" style="border-bottom: thin solid #000000;"><bold>Model 1</bold></th>
<th valign="top" align="center" colspan="3" style="border-bottom: thin solid #000000;"><bold>Model 2</bold></th>
<th valign="top" align="center" colspan="3" style="border-bottom: thin solid #000000;"><bold>Model 3</bold></th>
</tr>
<tr>
<th/>
<th valign="top" align="center"><bold>OR</bold></th>
<th valign="top" align="center"><bold>CI</bold></th>
<th valign="top" align="center"><bold><italic>P</italic></bold></th>
<th valign="top" align="center"><bold>OR</bold></th>
<th valign="top" align="center"><bold>CI</bold></th>
<th valign="top" align="center"><bold><italic>P</italic></bold></th>
<th valign="top" align="center"><bold>OR</bold></th>
<th valign="top" align="center"><bold>CI</bold></th>
<th valign="top" align="center"><bold><italic>P</italic></bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Age</td>
<td valign="top" align="center">0.87</td>
<td valign="top" align="center">0.78&#x02013;0.97</td>
<td valign="top" align="center">0.015</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">0.88</td>
<td valign="top" align="center">0.79&#x02013;0.98</td>
<td valign="top" align="center">0.025</td>
</tr>
<tr>
<td valign="top" align="left">Female gender</td>
<td valign="top" align="center">1.54</td>
<td valign="top" align="center">1.20&#x02013;1.99</td>
<td valign="top" align="center">0.001</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.57</td>
<td valign="top" align="center">1.21&#x02013;2.02</td>
<td valign="top" align="center">0.001</td>
</tr>
<tr>
<td valign="top" align="left">Education: low (ref.)</td>
<td valign="top" align="center">1.00</td>
<td valign="top" align="center">&#x02013;</td>
<td valign="top" align="center">&#x02013;</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.00</td>
<td valign="top" align="center">&#x02013;</td>
<td valign="top" align="center">&#x02013;</td>
</tr>
<tr>
<td valign="top" align="left">Education: middle</td>
<td valign="top" align="center">1.08</td>
<td valign="top" align="center">0.81&#x02013;1.43</td>
<td valign="top" align="center">0.615</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.37</td>
<td valign="top" align="center">1.03&#x02013;1.80</td>
<td valign="top" align="center">0.028</td>
</tr>
<tr>
<td valign="top" align="left">Education: high</td>
<td valign="top" align="center">1.34</td>
<td valign="top" align="center">0.97&#x02013;1.84</td>
<td valign="top" align="center">0.077</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.59</td>
<td valign="top" align="center">1.15&#x02013;2.19</td>
<td valign="top" align="center">0.005</td>
</tr>
<tr>
<td valign="top" align="left">Living alone</td>
<td valign="top" align="center">0.99</td>
<td valign="top" align="center">0.79&#x02013;1.23</td>
<td valign="top" align="center">0.926</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.01</td>
<td valign="top" align="center">0.81&#x02013;1.26</td>
<td valign="top" align="center">0.929</td>
</tr>
<tr>
<td valign="top" align="left">Rare personal contacts</td>
<td valign="top" align="center">1.07</td>
<td valign="top" align="center">0.82&#x02013;1.40</td>
<td valign="top" align="center">0.608</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.06</td>
<td valign="top" align="center">0.80&#x02013;1.41</td>
<td valign="top" align="center">0.689</td>
</tr>
<tr>
<td valign="top" align="left">SI: low (ref.)</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.00</td>
<td valign="top" align="center">&#x02013;</td>
<td valign="top" align="center">&#x02013;</td>
<td valign="top" align="center">1.00</td>
<td valign="top" align="center">&#x02013;</td>
<td valign="top" align="center">&#x02013;</td>
</tr>
<tr>
<td valign="top" align="left">SI: middle<xref ref-type="table-fn" rid="TN3"><sup>a</sup></xref></td>
<td/>
<td/>
<td/>
<td valign="top" align="center">1.05</td>
<td valign="top" align="center">0.86&#x02013;1.29</td>
<td valign="top" align="center">0.622</td>
<td valign="top" align="center">1.06</td>
<td valign="top" align="center">0.86&#x02013;1.30</td>
<td valign="top" align="center">0.593</td>
</tr>
<tr>
<td valign="top" align="left">SI: high<xref ref-type="table-fn" rid="TN4"><sup>b</sup></xref></td>
<td/>
<td/>
<td/>
<td valign="top" align="center">0.96</td>
<td valign="top" align="center">0.78&#x02013;1.19</td>
<td valign="top" align="center">0.730</td>
<td valign="top" align="center">1.10</td>
<td valign="top" align="center">0.87&#x02013;1.38</td>
<td valign="top" align="center">0.434</td>
</tr>
<tr>
<td valign="top" align="left">% COVID-19 cases</td>
<td/>
<td/>
<td/>
<td valign="top" align="center">3.95</td>
<td valign="top" align="center">2.01&#x02013;7.74</td>
<td valign="top" align="center">&#x0003C;0.001</td>
<td valign="top" align="center">4.12</td>
<td valign="top" align="center">2.15&#x02013;7.91</td>
<td valign="top" align="center">&#x0003C;0.001</td>
</tr>
<tr>
<td valign="top" align="left">Observations</td>
<td valign="top" align="center" colspan="3">10,306</td>
<td valign="top" align="center" colspan="3">10,306</td>
<td valign="top" align="center" colspan="3">10,306</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="TN3">
<label>a</label>
<p><italic>Middle stringency countries (reference: low stringency countries)</italic>.</p></fn>
<fn id="TN4">
<label>b</label>
<p><italic>High stringency countries (reference: low stringency countries)</italic>.</p></fn>
</table-wrap-foot>
</table-wrap>
</sec>
</sec>
<sec sec-type="discussion" id="s4">
<title>Discussion</title>
<p>The present study sought to describe the prevalence of decline in mental health among elderly persons in Europe during the COVID-19 pandemic and to analyse the associations of social factors, infection rates and government response measures with a decline in mental health.</p>
<sec>
<title>Summary of Main Findings</title>
<p>One finding was that the majority of older adults, who reported depressive symptoms or being nervous and/or anxious, showed a decline in mental health since the beginning of the COVID-19 pandemic. This holds true for respondents across all European countries. Although the proportion of people with a decline in mental health was higher in countries where the social life was affected by strict government response measures, even in countries with a milder response a majority of respondents reported an increase in depressive symptoms, nervousness, and anxiety. Regarding social factors, we found that increasing age and female gender were associated with a lower chance of a decline in mental health, while we found inconsistent or no associations for education, rare personal contacts and living alone. In terms of the macro indicators, there were positive associations with the proportion of infections in the population, but inconsistent results related to the stringency index.</p>
</sec>
<sec>
<title>Interpretation</title>
<p>Although the concrete impact of the COVID-19 pandemic on mental health is not yet fully understood, studies from former comparable outbreaks that required social restrictions or lockdown measures confirmed that the challenges and stress associated with such NPIs could trigger mental disorders, especially anxiety and depressive symptoms (<xref ref-type="bibr" rid="B11">11</xref>, <xref ref-type="bibr" rid="B31">31</xref>). This included both, an increase in the prevalence of disorders as well as worsening mental health (<xref ref-type="bibr" rid="B18">18</xref>). Beyond the impact of NPIs on mental health, the fear of serious health consequences might exert a further negative influence on mental well-being. The fact that especially older people were at higher risk for adverse health outcomes due to COVID-19 might explain why&#x02014;compared to surveys that also included younger populations&#x02014;we found a higher proportion of decline in mental health, which did not only occur in countries with strict government response measures. This is in line with studies that showed the negative psychological impact of the pandemic on the older population due to increased morbidity and mortality risks (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B32">32</xref>). In our study, we used infection rates of a population and the stringency index as two indicators on a macro level that reflect the pandemic threat and the rigidity of NPIs and found links between those indicators and a decline in mental health. Populations&#x00027; infection rates were strongly positively associated with feeling more depressed and more nervous/anxious. This can be explained with the health concerns of elderly people, who were a particular risk group for adverse COVID-19 related health outcomes. The perceived threat of the pandemic increased with higher proportions of infected cases in the population. This fear was in particular present in risk groups such as older people (<xref ref-type="bibr" rid="B33">33</xref>). We found no evidence that the government response measures, indicated by the stringency index, were associated with feeling more nervous and/or anxious. Feeling more depressed, however, was more likely for respondents living in countries with higher stringency index. Studies that analyzed the impact of lockdown measures and comparable NPIs also reported negative mental health consequences. A longitudinal study from South Africa showed that the prevalence of depression and anxiety symptoms was higher during the time of social restrictions (<xref ref-type="bibr" rid="B34">34</xref>). Another study from Israel indicated that such measures were the main risk factor for depression and anxiety (<xref ref-type="bibr" rid="B35">35</xref>).</p>
<p>According to our results, increasing age was associated with a lower chance of a decline in mental health. This seemed to be somewhat counter intuitive given that in particular elderly people were one of the most vulnerable risk groups related to COVID-19 and their emotional response toward the pandemic outbreak was more apparent than in younger age groups (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B36">36</xref>). Research on this topic revealed inconclusive results. While a documentary analysis indicated that mental health in older people was negatively affected by social restriction measures, another recent study found that adherence to such measures was not associated with a decline in mental health. One explanation might be that a key issue that serves as protective factor could be the social connectedness whose positive impact was rated higher than the negative impact of COVID-19 related worries (<xref ref-type="bibr" rid="B37">37</xref>, <xref ref-type="bibr" rid="B38">38</xref>).</p>
<p>A clear association was found between gender and decline in mental health, with female persons being more likely to be affected. This is in line with previous research that described significantly higher scores of psychological distress for female gender during the pandemic (<xref ref-type="bibr" rid="B13">13</xref>). One study reported significantly larger increase in depressive symptoms for female persons (<xref ref-type="bibr" rid="B37">37</xref>). A meta-analysis on the prevalence of depression and anxiety among COVID-19 patients also showed higher proportions of female patients being affected. However, the total effect of gender was not statistically significant (<xref ref-type="bibr" rid="B39">39</xref>).</p>
<p>The associations of education and decline in mental health differed between the two subgroups of respondents who were more depressed and those who felt more nervous and/or anxious. In the models with social factors only, higher education showed weak evidence for a lower probability of decline in mental health. In the full model, the association between education and feeling more depressed diminished, while we found a significant positive association between higher education and feeling more nervous and/or anxious. The latter result was supported by other research results. Recent longitudinal studies on the change of mental health in the course of COVID-19 showed that a higher educational level was associated with increases in mental health problems (<xref ref-type="bibr" rid="B40">40</xref>). A reason might be that higher educated persons may feel greater concerns about the consequences of COVID-19, which was also reported in a study from the US (<xref ref-type="bibr" rid="B41">41</xref>).</p>
<p>Regarding social relations, living alone was associated with feeling more sad or depressed, but this association diminished after controlling for the macro indicators. We did not find clear associations for living alone and feeling more nervous and/or anxious. Rare personal contacts were not statistically significant in any model. Although studies showed a positive impact of social contacts on mental health (<xref ref-type="bibr" rid="B17">17</xref>), other findings suggested that there was no clear link between social contacts and nervousness and anxiety for older individuals (<xref ref-type="bibr" rid="B42">42</xref>). An explanation for the inconsistent associations between social relations and decline in mental health could be that older persons experience less life changes due to the pandemic, making social contacts more important for younger generations (<xref ref-type="bibr" rid="B43">43</xref>).</p>
</sec>
<sec>
<title>Limitations</title>
<p>Some methodological limitations have to be considered that affect the interpretation of the findings. First, the SHARE data only provides some rather crude measures of decline in mental. An advantage of the mental health indicators we used is that they refer to acute and very recent mental health problems. On the other hand, it depends on a subjective perception of feeling depressed, nervous or anxious and is not measured by a validated assessment instrument for mental health disorders. Furthermore, the mental health indicators we used may only reflect a temporary condition and no longer lasting disorder. Nevertheless, we decided to use this indicator as it allowed us to measure a decline of mental health problems since the COVID-19 outbreak using cross-sectional data.</p>
<p>Another limitation is related to the measures of social relations, which might explain the inconsistent or unclear associations in our results. Only frequency of personal contacts, not telephone or digital contacts were assessed. Additionally, as rare personal contacts and living alone only refer to the quantitative dimension of social relations, they do not reflect qualitative or functional aspects. Furthermore, due to the age range in the sample, which defines older adults as persons aged 50 and older, respondents in the SHARE survey were a very heterogeneous group.</p>
<p>Finally, it is also important to mention that data collection was carried out in an early stage of the pandemic. Thus, our study refers to a rather short-term impact of NPIs on mental health, which might result in an underestimation of the associations between government measures and mental health. In addition, the impact of a pandemic outbreak on mental health is often influenced by many different factors. For instance, we could not include measures such as job security, loneliness, or other psycho-social factors. Nonetheless, one of the strengths of this study is the combination of a large dataset on an individual level combined with very well-prepared data on a macro level from other sources, which allowed us to gain more specific insights into the complex associations of social factors, infection rates, government response, and decline in mental health.</p>
</sec>
</sec>
<sec sec-type="conclusions" id="s5">
<title>Conclusions</title>
<p>A majority of European older adults, who reported depressive symptoms or being nervous and/or anxious, showed a decline in mental health since the beginning of the COVID-19 pandemic. This holds especially true in countries with high prevalence rates of COVID-19. Among older European adults, age seems to be a protective factor for a decline in mental health while female gender apparently is a risk factor. Moreover, looking at government response measures, we conclude that, despite those NPIs being an essential preventative mechanism to reduce the pandemic spread, they might influence the vulnerability for elderly people suffering from mental health problems.</p>
</sec>
<sec sec-type="data-availability" id="s6">
<title>Data Availability Statement</title>
<p>Publicly available datasets were analyzed in this study. This data can be found at: The SHARE data is available for research purpose after registering at the SHARE website (<ext-link ext-link-type="uri" xlink:href="http://www.share-project.org">www.share-project.org</ext-link>). Data from the Oxford COVID-19 Government Response Tracker (OxCGRT) is freely available at <ext-link ext-link-type="uri" xlink:href="https://github.com/OxCGRT/covid-policy-tracker">https://github.com/OxCGRT/covid-policy-tracker</ext-link>. The COVID-19 Data Repository stores data on COVID cases and is located at <ext-link ext-link-type="uri" xlink:href="https://github.com/CSSEGISandData/COVID-19">https://github.com/CSSEGISandData/COVID-19</ext-link>. All websites were lastly accessed on 9 February 2022.</p>
</sec>
<sec id="s7">
<title>Ethics Statement</title>
<p>The studies involving human participants were reviewed and approved by Ethics Council of the Max Planck Society. The patients/participants provided their written informed consent to participate in this study.</p>
</sec>
<sec id="s8">
<title>Author Contributions</title>
<p>DL and OK developed the research questions. DL prepared, analyzed and interpreted the data, and drafted and finalized the manuscript. OK substantially contributed to interpreting the data, drafting the manuscript, and critically revised and approved the final manuscript. All authors contributed to the article and approved the submitted version.</p>
</sec>
<sec sec-type="funding-information" id="s9">
<title>Funding</title>
<p>The SHARE data collection was primarily funded by the European Commission through FP5 (QLK6-CT-2001-00360), FP6 (SHARE-I3: RII-CT-2006-062193, COMPARE: CIT5-CT-2005-028857, SHARELIFE: CIT4-CT-2006-028812) and FP7 (SHARE-PREP: N&#x000B0;211909, SHARE-LEAP: N&#x000B0;227822, SHARE M4: N&#x000B0;261982). Additional funding from the German Ministry of Education and Research, the US National Institute on Aging (U01_AG09740-13S2, P01_AG005842, P01_AG08291, P30_AG12815, R21_AG025169, Y1-AG-4553-01, IAG_BSR06-11, OGHA_04-064) and from various national funding sources is gratefully acknowledged (see <ext-link ext-link-type="uri" xlink:href="http://www.share-project.org">www.share-project.org</ext-link>, last accessed 27 December 2021).</p>
</sec>
<sec sec-type="COI-statement" id="conf1">
<title>Conflict of Interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="disclaimer" id="s10">
<title>Publisher&#x00027;s Note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
</body>
<back>
<ack><p>This article uses data from SHARE Wave 8. Please see (<xref ref-type="bibr" rid="B20">20</xref>) for methodological details. Source code to replicate the results is available in R format at <ext-link ext-link-type="uri" xlink:href="https://osf.io/stja8/">https://osf.io/stja8/</ext-link>.</p>
</ack>
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