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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Public Health</journal-id>
<journal-title>Frontiers in Public Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Public Health</abbrev-journal-title>
<issn pub-type="epub">2296-2565</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpubh.2022.1072515</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Public Health</subject>
<subj-group>
<subject>Original Research</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>COVI-Prim international: Similarities and discrepancies in the way general practices from seven different countries coped with the COVID-19 pandemic</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name><surname>Siebenhofer</surname> <given-names>Andrea</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="author-notes" rid="fn002"><sup>&#x02020;</sup></xref>
<xref ref-type="author-notes" rid="fn003"><sup>&#x02021;</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Scott</surname> <given-names>Anna Mae</given-names></name>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
<xref ref-type="author-notes" rid="fn002"><sup>&#x02020;</sup></xref>
<xref ref-type="author-notes" rid="fn004"><sup>&#x02021;</sup></xref>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name><surname>Avian</surname> <given-names>Alexander</given-names></name>
<xref ref-type="aff" rid="aff4"><sup>4</sup></xref>
<xref ref-type="corresp" rid="c001"><sup>&#x0002A;</sup></xref>
<xref ref-type="author-notes" rid="fn005"><sup>&#x02021;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/401210/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Terebessy</surname> <given-names>Andr&#x000E1;s</given-names></name>
<xref ref-type="aff" rid="aff5"><sup>5</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Mergenthal</surname> <given-names>Karola</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="author-notes" rid="fn006"><sup>&#x02021;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/1668312/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Schaffler-Schaden</surname> <given-names>Dagmar</given-names></name>
<xref ref-type="aff" rid="aff6"><sup>6</sup></xref>
<xref ref-type="author-notes" rid="fn007"><sup>&#x02021;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/1157539/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Bachler</surname> <given-names>Herbert</given-names></name>
<xref ref-type="aff" rid="aff7"><sup>7</sup></xref>
<xref ref-type="author-notes" rid="fn008"><sup>&#x02021;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/1620090/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Huter</surname> <given-names>Sebastian</given-names></name>
<xref ref-type="aff" rid="aff6"><sup>6</sup></xref>
<xref ref-type="author-notes" rid="fn009"><sup>&#x02021;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/1450562/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Zelko</surname> <given-names>Erika</given-names></name>
<xref ref-type="aff" rid="aff8"><sup>8</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Murray</surname> <given-names>Amanda</given-names></name>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Guppy</surname> <given-names>Michelle</given-names></name>
<xref ref-type="aff" rid="aff9"><sup>9</sup></xref>
<xref ref-type="author-notes" rid="fn010"><sup>&#x02021;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/163968/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Piccoliori</surname> <given-names>Giuliano</given-names></name>
<xref ref-type="aff" rid="aff10"><sup>10</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Streit</surname> <given-names>Sven</given-names></name>
<xref ref-type="aff" rid="aff11"><sup>11</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Jeitler</surname> <given-names>Klaus</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff4"><sup>4</sup></xref>
<xref ref-type="author-notes" rid="fn011"><sup>&#x02021;</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Flamm</surname> <given-names>Maria</given-names></name>
<xref ref-type="aff" rid="aff6"><sup>6</sup></xref>
<xref ref-type="author-notes" rid="fn012"><sup>&#x02021;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/1668178/overview"/>
</contrib>
</contrib-group>
<aff id="aff1"><sup>1</sup><institution>Institute of General Practice and Evidence-Based Health Services Research, Medical University of Graz</institution>, <addr-line>Graz</addr-line>, <country>Austria</country></aff>
<aff id="aff2"><sup>2</sup><institution>Institute of General Practice, Johann Wolfgang Goethe University Frankfurt</institution>, <addr-line>Frankfurt</addr-line>, <country>Germany</country></aff>
<aff id="aff3"><sup>3</sup><institution>Institute for Evidence-Based Healthcare, Bond University</institution>, <addr-line>Gold Coast, QL</addr-line>, <country>Australia</country></aff>
<aff id="aff4"><sup>4</sup><institution>Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz</institution>, <addr-line>Graz</addr-line>, <country>Austria</country></aff>
<aff id="aff5"><sup>5</sup><institution>Department of Public Health-Faculty of Medicine, Semmelweis University</institution>, <addr-line>Budapest</addr-line>, <country>Hungary</country></aff>
<aff id="aff6"><sup>6</sup><institution>Institute for General Practice, Family Medicine and Preventive Medicine, Paracelsus Medical University</institution>, <addr-line>Salzburg</addr-line>, <country>Austria</country></aff>
<aff id="aff7"><sup>7</sup><institution>Institute of General Practice, Medical University of Innsbruck</institution>, <addr-line>Innsbruck</addr-line>, <country>Austria</country></aff>
<aff id="aff8"><sup>8</sup><institution>Faculty of Medicine, Johannes Kepler University of Linz</institution>, <addr-line>Linz</addr-line>, <country>Austria</country></aff>
<aff id="aff9"><sup>9</sup><institution>School of Rural Medicine and New England GP Research Network, University of New England</institution>, <addr-line>Armidale, NSW</addr-line>, <country>Australia</country></aff>
<aff id="aff10"><sup>10</sup><institution>Institute for Special Training in General Medicine, Institute of General Practice, Claudiana Bozen</institution>, <addr-line>Bolzano</addr-line>, <country>Italy</country></aff>
<aff id="aff11"><sup>11</sup><institution>Institute of Primary Health Care (BIHAM), University of Bern</institution>, <addr-line>Bern</addr-line>, <country>Switzerland</country></aff>
<author-notes>
<fn fn-type="edited-by"><p>Edited by: Redhwan Ahmed Al-Naggar, National University of Malaysia, Malaysia</p></fn>
<fn fn-type="edited-by"><p>Reviewed by: Yu Xiao, Chengdu No. 4 People&#x00027;s Hospital, China; Dilaver Tengilimo&#x0011F;lu, At&#x00131;l&#x00131;m University, Turkey</p></fn>
<corresp id="c001">&#x0002A;Correspondence: Alexander Avian <email>alexander.avian&#x00040;medunigraz.at</email></corresp>
<fn fn-type="other" id="fn001"><p>This article was submitted to Family Medicine and Primary Care, a section of the journal Frontiers in Public Health</p></fn>
<fn fn-type="equal" id="fn002"><p>&#x02020;These authors have contributed equally to this work and share first authorship</p></fn>
<fn fn-type="other" id="fn003"><p>&#x02021;ORCID: Andrea Siebenhofer <ext-link ext-link-type="uri" xlink:href="https://orcid.org/0000-0002-6980-2103">orcid.org/0000-0002-6980-2103</ext-link></p></fn>
<fn fn-type="other" id="fn004"><p>Anna Mae Scott <ext-link ext-link-type="uri" xlink:href="https://orcid.org/0000-0002-0109-9001">orcid.org/0000-0002-0109-9001</ext-link></p></fn>
<fn fn-type="other" id="fn005"><p>Alexander Avian <ext-link ext-link-type="uri" xlink:href="https://orcid.org/0000-0003-1084-5763">orcid.org/0000-0003-1084-5763</ext-link></p></fn>
<fn fn-type="other" id="fn006"><p>Karola Mergenthal <ext-link ext-link-type="uri" xlink:href="https://orcid.org/0000-0002-0534-9389">orcid.org/0000-0002-0534-9389</ext-link></p></fn>
<fn fn-type="other" id="fn007"><p>Dagmar Schaffler-Schaden <ext-link ext-link-type="uri" xlink:href="https://orcid.org/0000-0002-9311-7413">orcid.org/0000-0002-9311-7413</ext-link></p></fn>
<fn fn-type="other" id="fn008"><p>Herbert Bachler <ext-link ext-link-type="uri" xlink:href="https://orcid.org/0000-0001-5859-206X">orcid.org/0000-0001-5859-206X</ext-link></p></fn>
<fn fn-type="other" id="fn009"><p>Sebastian Huter <ext-link ext-link-type="uri" xlink:href="https://orcid.org/0000-0002-6632-6834">orcid.org/0000-0002-6632-6834</ext-link></p></fn>
<fn fn-type="other" id="fn010"><p>Michelle Guppy <ext-link ext-link-type="uri" xlink:href="https://orcid.org/0000-0001-7256-4938">orcid.org/0000-0001-7256-4938</ext-link></p></fn>
<fn fn-type="other" id="fn011"><p>Klaus Jeitler <ext-link ext-link-type="uri" xlink:href="https://orcid.org/0000-0002-1520-8061">orcid.org/0000-0002-1520-8061</ext-link></p></fn>
<fn fn-type="other" id="fn012"><p>Maria Flamm <ext-link ext-link-type="uri" xlink:href="https://orcid.org/0000-0003-0816-6657">orcid.org/0000-0003-0816-6657</ext-link></p></fn></author-notes>
<pub-date pub-type="epub">
<day>06</day>
<month>12</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="collection">
<year>2022</year>
</pub-date>
<volume>10</volume>
<elocation-id>1072515</elocation-id>
<history>
<date date-type="received">
<day>17</day>
<month>10</month>
<year>2022</year>
</date>
<date date-type="accepted">
<day>22</day>
<month>11</month>
<year>2022</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x000A9; 2022 Siebenhofer, Scott, Avian, Terebessy, Mergenthal, Schaffler-Schaden, Bachler, Huter, Zelko, Murray, Guppy, Piccoliori, Streit, Jeitler and Flamm.</copyright-statement>
<copyright-year>2022</copyright-year>
<copyright-holder>Siebenhofer, Scott, Avian, Terebessy, Mergenthal, Schaffler-Schaden, Bachler, Huter, Zelko, Murray, Guppy, Piccoliori, Streit, Jeitler and Flamm</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license></permissions>
<abstract>
<sec>
<title>Objectives</title>
<p>General practitioners (GPs) are frequently patients&#x00027; first point of contact with the healthcare system and play an important role in identifying, managing and monitoring cases. This study investigated the experiences of GPs from seven different countries in the early phases of the COVID-19 pandemic.</p></sec>
<sec>
<title>Design</title>
<p>International cross-sectional online survey.</p></sec>
<sec>
<title>Setting</title>
<p>General practitioners from Australia, Austria, Germany, Hungary, Italy, Slovenia and Switzerland.</p></sec>
<sec>
<title>Participants</title>
<p>Overall, 1,642 GPs completed the survey.</p></sec>
<sec>
<title>Main outcome measures</title>
<p>We focused on how well-prepared GPs were, their self-confidence and concerns, efforts to control the spread of the disease, patient contacts, information flow, testing procedures and protection of staff.</p></sec>
<sec>
<title>Results</title>
<p>GPs gave high ratings to their self-confidence (7.3, 95% CI 7.1&#x02013;7.5) and their efforts to control the spread of the disease (7.2, 95% CI 7.0&#x02013;7.3). A decrease in the number of patient contacts (5.7, 95% CI 5.4&#x02013;5.9), the perception of risk (5.3 95% CI 4.9&#x02013;5.6), the provision of information to GPs (4.9, 95% CI 4.6&#x02013;5.2), their testing of suspected cases (3.7, 95% CI 3.4&#x02013;3.9) and their preparedness to face a pandemic (mean: 3.5; 95% CI 3.2&#x02013;3.7) were rated as moderate. GPs gave low ratings to their ability to protect staff (2.2 95% CI 1.9&#x02013;2.4). Differences were identified in all dimensions except protection of staff, which was consistently low in all surveyed GPs and countries.</p></sec>
<sec>
<title>Conclusion</title>
<p>Although GPs in the different countries were confronted with the same pandemic, its impact on specific aspects differed. This partly reflected differences in health care systems and experience of recent pandemics. However, it also showed that the development of structured care plans in case of future infectious diseases requires the early involvement of primary care representatives.</p></sec></abstract>
<kwd-group>
<kwd>COVID-19</kwd>
<kwd>general practitioner (GP)</kwd>
<kwd>public health</kwd>
<kwd>self-confidence</kwd>
<kwd>perception of risk</kwd>
</kwd-group>
<counts>
<fig-count count="1"/>
<table-count count="2"/>
<equation-count count="0"/>
<ref-count count="51"/>
<page-count count="10"/>
<word-count count="7359"/>
</counts>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="s1">
<title>Introduction</title>
<p>Following the reports of the first cases of COVID-19 in late 2019, the World Health Organization declared COVID-19 to be a Public Health Emergency of International Concern on 30<sup>th</sup> January 2020, and a pandemic on 11<sup>th</sup> March 2020 (<xref ref-type="bibr" rid="B1">1</xref>). Two years later, on 11<sup>th</sup> March 2022, over 450 million cases of COVID-19, and over 6 million deaths, had been reported to the World Health Organization worldwide (<xref ref-type="bibr" rid="B2">2</xref>).</p>
<p>The pandemic has put unprecedented strain on healthcare systems, and, amongst other aspects, has had a profound effect on healthcare staff, healthcare delivery and utilization (<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B4">4</xref>). However, the focus of research has been on evaluating the pandemic&#x00027;s impact on hospital care and inpatient staff. Relatively little attention has been paid to its impact on primary care and on primary healthcare providers (<xref ref-type="bibr" rid="B5">5</xref>, <xref ref-type="bibr" rid="B6">6</xref>).</p>
<p>The importance of primary care in dealing with this&#x02014;or any other&#x02014;pandemic, cannot be understated. It is the primary healthcare setting that is frequently the patient&#x00027;s first point of contact with the healthcare system (<xref ref-type="bibr" rid="B7">7</xref>), and primary care providers play a substantial role in identifying, managing and monitoring cases (<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B9">9</xref>).</p>
<p>Existing evidence suggests that the pandemic&#x00027;s impact on primary care has been considerable and multi-faceted (<xref ref-type="bibr" rid="B6">6</xref>). General Practitioners (GPs) in Italy, for example, have reported a high prevalence of adverse mental health outcomes, such as anxiety, depression and burnout (<xref ref-type="bibr" rid="B5">5</xref>). Changes have also occurred in the delivery of primary care, with GPs in many countries shifting from face-to-face consultations to remote telehealth consultations (e.g., phone or videoconferencing) (<xref ref-type="bibr" rid="B5">5</xref>, <xref ref-type="bibr" rid="B6">6</xref>, <xref ref-type="bibr" rid="B8">8</xref>). Care has also tended to focus less than usual on chronic care (<xref ref-type="bibr" rid="B10">10</xref>), with diabetes, COPD, and hypertension being the most impacted conditions (<xref ref-type="bibr" rid="B11">11</xref>). Preventive healthcare, and cancer screening in particular, were also affected considerably (<xref ref-type="bibr" rid="B12">12</xref>). These changes are ongoing and are expected to have a negative long-term influence on health outcomes. Primary care providers will continue to play an important role in managing future waves of the pandemic, and in providing care to patients with long COVID and other conditions that tend to be aggravated in pandemics, such as anxiety disorders.</p>
<p>The aim of our study was to investigate the experiences of GPs in seven countries (Australia, Austria, Germany, Hungary, Italy, Slovenia, and Switzerland), in the early phases of the COVID-19 pandemic (<xref ref-type="bibr" rid="B13">13</xref>). We focused on GPs&#x00027; preparedness to face a pandemic, their self-confidence and concerns, efforts to control the spread of the disease, patient contacts, information flow, testing procedures and on how well they felt their staff were protected.</p></sec>
<sec sec-type="methods" id="s2">
<title>Methods</title>
<p>This manuscript was prepared in accordance with the CHERRIES criteria (<xref ref-type="bibr" rid="B14">14</xref>). COVI-Prim-<italic>International</italic> is part of the COVI-Prim project, which is described in detail elsewhere (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B15">15</xref>). Briefly, GPs in seven different countries (Australia, Austria, Germany, Hungary, Italy, Slovenia, and Switzerland) were invited to answer a basic questionnaire. In two countries (Austria and Germany) further questionnaires were sent to participating GPs at regular intervals (<xref ref-type="bibr" rid="B16">16</xref>).</p>
<p>We first analyzed the baseline questionnaire that was distributed as part of the COVI-Prim-<italic>International</italic> project [48 closed items, eight dimensions: (1) self-confidence, (2) efforts to control the spread of the disease, (3) decrease in number of patient contacts, (4) perception of risk, (5) provision of information to GP, (6) testing suspected cases, (7) preparedness for a pandemic, (8) protection of staff; factor scores ranged from 0 to 10]. The questionnaire was transferred to LimeSurvey<sup>&#x000AE;</sup> (Austria, Germany, Hungary, Italy, Slovenia, and Switzerland) or SurveyMonkey<sup>&#x000AE;</sup> (Australia). Invitations to GPs to respond to the questionnaire were sent out based on the mailing lists of participating universities and local GP associations. As the lists probably overlapped, it is not possible to know precisely how many GPs were contacted and hence to calculate a response rate. Participants were first informed about the length of the survey, the investigators, and the purpose of the study. After the survey had been completed, all data on the online platform were stored in SPSS files. GPs received no financial incentive to participate. Surveys started at different time points in the participating countries. In most countries, GPs first began to answer the survey when the number of patients testing positively had begun to decrease. Completion rates ranged from 63.3% in Slovenia to 91.7% in Australia. The median time required to answer the questionnaire ranged from 11.0 min in Australia (interquartile range: 7.6&#x02013;15.1) to 17.3 (IQR: 12.0&#x02013;22.5) in Italy. Further details on completion rates and the time required to answer the questionnaire are reported elsewhere (<xref ref-type="bibr" rid="B13">13</xref>). In order to examine comparable situations in different countries, periods of time were chosen during which infection dynamics were similar. Since in some countries the survey did not commence until after the peak of the first wave of infections, we only included GPs that had answered the baseline questionnaire from that point onwards. The first day considered in this analysis was therefore defined as the day on which the number of new infections first fell below 2/3 of the maximum number of new infections observed during the first wave. GPs that answered the survey after April 3rd in Australia, April 4th in Austria, April 9th in Switzerland, April 11th in Slovenia, April 13th in Germany, April 15th in Italy and after May 3rd in Hungary were therefore included.</p>
<sec>
<title>Statistics</title>
<p>Baseline characteristics are presented as mean &#x000B1;SD or median (min&#x02014;max), as appropriate. Categorical variables are provided as absolute numbers and percentages. In the main analysis, environmental variables (country of survey; size of town in which practice was located: &#x0003C;5,000/5,000 to &#x0003C;20,000/20,000 to &#x0003C;100,000/&#x02265;100,000) that may have influenced the responses, and the role of the GP within the practice (employed vs. owner), were analyzed using General Linear Models. The main effects and all two-way interactions were analyzed. Bonferroni correction was used to take account of multiple testing. Estimated means and 95% confidence intervals were used to present the results. For a better understanding of the results, responses to the items on each scale were also presented. In this presentation, the response categories &#x0201C;yes&#x0201D; and &#x0201C;yes, probably&#x0201D; and the response categories &#x0201C;no, probably not&#x0201D; and &#x0201C;no&#x0201D; were combined. No statistical correction was carried out to adjust for non-representative samples.</p></sec>
<sec>
<title>Ethics</title>
<p>The study protocol was approved by the Ethics Committee of Bond University, Australia (AS200424), Goethe University Frankfurt, Germany (ID 20-619). The study required no ethical approval under Austrian, Italian, Slovenian, Swiss, and Hungarian law.</p></sec></sec>
<sec sec-type="results" id="s3">
<title>Results</title>
<sec>
<title>Demographics</title>
<p>The survey was filled out by 1,642 GPs from Australia (<italic>n</italic> = 120), Austria (<italic>n</italic> = 434), Germany (<italic>n</italic> = 583), Hungary (<italic>n</italic> = 190), Italy (<italic>n</italic> = 112), Slovenia (<italic>n</italic> = 86), and Switzerland (<italic>n</italic> = 117). Mean age of the GPs was 51.9 years (SD: 10.8). The majority of GPs were male (52.1%) and practiced in a city with fewer than 20,000 inhabitants (56.6%). All demographic characteristics are provided in <xref ref-type="table" rid="T1">Table 1</xref>.</p>
<table-wrap position="float" id="T1">
<label>Table 1</label>
<caption><p>Baseline demographics.</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th/>
<th valign="top" align="center"><bold>All</bold></th>
</tr>
<tr>
<th/>
<th valign="top" align="center"><bold><italic>n</italic> = 1,642</bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left"><bold>Country</bold></td>
<td/>
</tr>
<tr>
<td valign="top" align="left">Australia</td>
<td valign="top" align="center">120 (7.3%)</td>
</tr>
<tr>
<td valign="top" align="left">Austria</td>
<td valign="top" align="center">434 (26.4%)</td>
</tr>
<tr>
<td valign="top" align="left">Germany</td>
<td valign="top" align="center">583 (35.5%)</td>
</tr>
<tr>
<td valign="top" align="left">Hungary</td>
<td valign="top" align="center">190 (11.6%)</td>
</tr>
<tr>
<td valign="top" align="left">Italy</td>
<td valign="top" align="center">112 (6.8%)</td>
</tr>
<tr>
<td valign="top" align="left">Slovenia</td>
<td valign="top" align="center">86 (5.2%)</td>
</tr>
<tr>
<td valign="top" align="left">Switzerland</td>
<td valign="top" align="center">117 (7.1%)</td>
</tr>
<tr>
<td valign="top" align="left"><bold>Age</bold></td>
<td valign="top" align="center">51.9 &#x000B1; 10.8</td>
</tr>
<tr>
<td valign="top" align="left"><bold>Sex</bold></td>
<td/>
</tr>
<tr>
<td valign="top" align="left">Male</td>
<td valign="top" align="center">855 (52.1%)</td>
</tr>
<tr>
<td valign="top" align="left">Female</td>
<td valign="top" align="center">780 (47.5%)</td>
</tr>
<tr>
<td valign="top" align="left">Other</td>
<td valign="top" align="center">7 (0.4%)</td>
</tr>
<tr>
<td valign="top" align="left"><bold>Size of town of practice</bold></td>
<td/>
</tr>
<tr>
<td valign="top" align="left">&#x0003C;5,000</td>
<td valign="top" align="center">454 (27.6%)</td>
</tr>
<tr>
<td valign="top" align="left">5,000&#x02013; &#x0003C;20,000</td>
<td valign="top" align="center">474 (28.9%)</td>
</tr>
<tr>
<td valign="top" align="left">20,000&#x02013; &#x0003C;100,000</td>
<td valign="top" align="center">270 (16.4%)</td>
</tr>
<tr>
<td valign="top" align="left">&#x02265;100,000</td>
<td valign="top" align="center">443 (27.0%)</td>
</tr>
<tr>
<td valign="top" align="left">Missing</td>
<td valign="top" align="center">1 (0.1%)</td>
</tr>
<tr>
<td valign="top" align="left"><bold>Position in the practice</bold></td>
<td/>
</tr>
<tr>
<td valign="top" align="left">Employed</td>
<td valign="top" align="center">356 (21.7%)</td>
</tr>
<tr>
<td valign="top" align="left">Owner</td>
<td valign="top" align="center">1,284 (78.2%)</td>
</tr>
<tr>
<td valign="top" align="left">Missing</td>
<td valign="top" align="center">2 (0.1%)</td>
</tr>
<tr>
<td valign="top" align="left"><bold>Year practice was set up</bold></td>
<td valign="top" align="center">Median: 2003</td>
</tr>
<tr>
<td/>
<td valign="top" align="center">IQR: 1992&#x02013;2012</td>
</tr>
</tbody>
</table>
</table-wrap></sec>
<sec>
<title>Overall results</title>
<p>GPs gave high ratings to their self-confidence (7.3, 95% CI 7.1&#x02013;7.5) and their efforts to control the spread of the disease (7.2, 95% CI 7.0&#x02013;7.3). The decrease in the number of patient contacts (5.7, 95% CI 5.4&#x02013;5.9), GPs&#x00027; perception of risk (5.3 95% CI 4.9&#x02013;5.6), the provision of information to GPs (4.9, 95% CI 4.6&#x02013;5.2), testing of suspected cases (3.7, 95% CI 3.4&#x02013;3.9) and their preparedness for a pandemic (mean: 3.5; 95% CI 3.2&#x02013;3.7) were rated as moderate. GPs gave low ratings to their efforts to protect staff (2.2 95% CI 1.9&#x02013;2.4).</p></sec>
<sec>
<title>Differences between countries</title>
<sec>
<title>Self-confidence</title>
<p>Austrian GPs rated their self-confidence (8.0, 95% CI 7.5&#x02013;8.5) significantly higher than Hungarian (6.7, 95% CI 6.3&#x02013;7.2, <italic>p</italic> = 0.043) and Italian GPs (6.3, 95% CI 5.6&#x02013;7.1, <italic>p</italic> = 0.036). More Austrian GPs were further convinced they knew how to provide the best possible care to their patients during the pandemic (AT: 88.2%, HU: 76.1%, IT: 69.7%) (<xref ref-type="supplementary-material" rid="SM1">Supplementary Table S1</xref>).</p></sec>
<sec>
<title>Efforts to control the spread of the disease</title>
<p>Slovenian GPs rated their efforts to control the spread of the virus in the practice (8.0, 95% CI 7.5&#x02013;8.6) more highly than Hungarian GPs (6.5, 95% CI 6.2&#x02013;6.9, <italic>p</italic> = 0.003). The most pronounced differences between Slovenian and Hungarian GPs were observed in the number of GPs contacting patients that were quarantined at home in order to monitor the progression of the disease (SI: 72.2%, HU: 2.0%), and in the number of GPs that preferred to treat patients with mild illnesses that were not linked to suspected cases of COVID-19 by phone or online (SI: 98.4%, HU: 65.4%).</p></sec>
<sec>
<title>Decrease in number of patient contacts</title>
<p>German GPs estimated the decrease in the number of patient contacts (7.2, 95% CI 6.9&#x02013;7.4) to have been significantly higher than did Australian (5.8, 95% CI 5.2&#x02013;6.3, <italic>p</italic> &#x0003C; 0.001), Hungarian (5.6, 95% CI 5.0 to 6.1, <italic>p</italic> &#x0003C; 0.001), Italian (4.6, 95% CI 3.7&#x02013;5.4, <italic>p</italic> &#x0003C; 0.001) and Slovenian (4.3, 95% CI 3.4&#x02013;5.1, <italic>p</italic> &#x0003C; 0.001) GPs. Furthermore, Austrian GPs reported the decrease in the number of patient contacts (6.3, 95% CI 5.7&#x02013;6.9, <italic>p</italic> = 0.007) was significantly higher than did Slovenian GPs.</p></sec>
<sec>
<title>Perception of risk</title>
<p>Austrian GPs perceived the risks they faced (3.9, 95% CI 3.2&#x02013;4.7) to be considerably lower than did Hungarian (6.0, 95% CI 5.3&#x02013;6.6, <italic>p</italic> = 0.010) Australian (6.0, 95% CI 5.3&#x02013;6.7, <italic>p</italic> = 0.006) and Italian (6.4, 95% CI 5.3&#x02013;7.5, <italic>p</italic> = 0.023) GPs (<xref ref-type="table" rid="T2">Table 2</xref>, <xref ref-type="fig" rid="F1">Figure 1</xref>). On an item level, the biggest difference between Austrian and Australian GPs was in their perception of their employees&#x00027; concerns about catching COVID-19 from patients (AU: 72.1 vs. AT: 37.2%). As far as the conflict between wanting to care for their patients but at the same time not wishing to endanger their families was concerned, the biggest differences were between Austrian, and Hungarian and Italian GPs (AT: 46.8, HU 68.4, IT: 70.1%).</p>
<table-wrap position="float" id="T2">
<label>Table 2</label>
<caption><p>Mean and 95% CI for each factor used in the evaluation of the pandemic for participating countries.</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th/>
<th valign="top" align="center" style="border-bottom: thin solid #000000;" colspan="7"><bold>Country</bold></th>
</tr>
<tr>
<th/>
<th valign="top" align="center"><bold>Australia</bold></th>
<th valign="top" align="center"><bold>Austria</bold></th>
<th valign="top" align="center"><bold>Germany</bold></th>
<th valign="top" align="center"><bold>Hungary</bold></th>
<th valign="top" align="center"><bold>Italy</bold></th>
<th valign="top" align="center"><bold>Slovenia</bold></th>
<th valign="top" align="center"><bold>Switzerland</bold></th>
</tr>
<tr>
<th/>
<th valign="top" align="center"><bold>A</bold></th>
<th valign="top" align="center"><bold>B</bold></th>
<th valign="top" align="center"><bold>C</bold></th>
<th valign="top" align="center"><bold>D</bold></th>
<th valign="top" align="center"><bold>E</bold></th>
<th valign="top" align="center"><bold>F</bold></th>
<th valign="top" align="center"><bold>G</bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Self confidence</td>
<td valign="top" align="center">7.7 (7.3&#x02013;8.1)</td>
<td valign="top" align="center"><bold>8.0 (7.5</bold>&#x02013;<bold>8.5)</bold><xref ref-type="table-fn" rid="TN4"><sup>D</sup></xref>, <xref ref-type="table-fn" rid="TN5"><sup>E</sup></xref></td>
<td valign="top" align="center">7.3 (7.1&#x02013;7.5)</td>
<td valign="top" align="center"><bold>6.7 (6.3</bold>&#x02013;<bold>7.2)</bold><xref ref-type="table-fn" rid="TN2"><sup>B</sup></xref></td>
<td valign="top" align="center"><bold>6.3 (5.6&#x02013;7.1)</bold><xref ref-type="table-fn" rid="TN2"><sup>B</sup></xref></td>
<td valign="top" align="center">7.2 (6.6&#x02013;7.9)</td>
<td valign="top" align="center">7.6 (6.8&#x02013;8.4)</td>
</tr>
<tr>
<td valign="top" align="left">Efforts to control the spread of the disease in the practice</td>
<td valign="top" align="center">7.2 (6.8&#x02013;7.5)</td>
<td valign="top" align="center">7.2 (6.8&#x02013;7.6)</td>
<td valign="top" align="center">7.0 (6.8&#x02013;7.1)</td>
<td valign="top" align="center"><bold>6.5 (6.2</bold> to <bold>6.9)</bold><xref ref-type="table-fn" rid="TN6"><sup>F</sup></xref></td>
<td valign="top" align="center">7.5 (6.9&#x02013;8.1)</td>
<td valign="top" align="center"><bold>8.0 (7.5</bold>&#x02013;<bold>8.6)</bold><xref ref-type="table-fn" rid="TN4"><sup>D</sup></xref></td>
<td valign="top" align="center">6.7 (6.0&#x02013;7.3)</td>
</tr>
<tr>
<td valign="top" align="left">Decrease in number of patient contacts</td>
<td valign="top" align="center"><bold>5.8 (5.2</bold>&#x02013;<bold>6.3)</bold><xref ref-type="table-fn" rid="TN3"><sup>C</sup></xref></td>
<td valign="top" align="center"><bold>6.3 (5.7</bold>&#x02013;<bold>6.9)</bold><xref ref-type="table-fn" rid="TN6"><sup>F</sup></xref></td>
<td valign="top" align="center"><bold>7.2 (6.9</bold>&#x02013;<bold>7.4)</bold><xref ref-type="table-fn" rid="TN1"><sup>A</sup></xref>, <xref ref-type="table-fn" rid="TN4"><sup>D</sup></xref>, <xref ref-type="table-fn" rid="TN5"><sup>E</sup></xref>, <xref ref-type="table-fn" rid="TN6"><sup>F</sup></xref></td>
<td valign="top" align="center"><bold>5.6 (5.0</bold>&#x02013;<bold>6.1)</bold><xref ref-type="table-fn" rid="TN3"><sup>C</sup></xref></td>
<td valign="top" align="center"><bold>4.6 (3.7</bold>&#x02013;<bold>5.4)</bold><xref ref-type="table-fn" rid="TN3"><sup>C</sup></xref></td>
<td valign="top" align="center"><bold>4.3 (3.4</bold>&#x02013;<bold>5.1)</bold><xref ref-type="table-fn" rid="TN2"><sup>B</sup></xref>, <xref ref-type="table-fn" rid="TN3"><sup>C</sup></xref></td>
<td valign="top" align="center">6.0 (5.0&#x02013;6.9)</td>
</tr>
<tr>
<td valign="top" align="left">Perception of risk</td>
<td valign="top" align="center"><bold>6.0 (5.3</bold>&#x02013;<bold>6.7)</bold><xref ref-type="table-fn" rid="TN2"><sup>B</sup></xref></td>
<td valign="top" align="center"><bold>3.9 (3.2</bold>&#x02013;<bold>4.7)</bold><xref ref-type="table-fn" rid="TN1"><sup>A</sup></xref>, <xref ref-type="table-fn" rid="TN4"><sup>D</sup></xref>, <xref ref-type="table-fn" rid="TN5"><sup>E</sup></xref></td>
<td valign="top" align="center">5.1 (4.8&#x02013;5.4)</td>
<td valign="top" align="center"><bold>6.0 (5.3</bold>&#x02013;<bold>6.6)</bold><xref ref-type="table-fn" rid="TN2"><sup>B</sup></xref></td>
<td valign="top" align="center"><bold>6.4 (5.3</bold>&#x02013;<bold>7.5)</bold><xref ref-type="table-fn" rid="TN2"><sup>B</sup></xref></td>
<td valign="top" align="center">5.6 (4.6&#x02013;6.6)</td>
<td valign="top" align="center">3.9 (2.7&#x02013;5.1)</td>
</tr>
<tr>
<td valign="top" align="left">Provision of information to GPs</td>
<td valign="top" align="center"><bold>5.9 (5.3</bold>&#x02013;<bold>6.5)</bold><xref ref-type="table-fn" rid="TN2"><sup>B</sup></xref>, <xref ref-type="table-fn" rid="TN3"><sup>C</sup></xref>, <xref ref-type="table-fn" rid="TN5"><sup>E</sup></xref></td>
<td valign="top" align="center"><bold>4.2 (3.5</bold>&#x02013;<bold>4.9)</bold><xref ref-type="table-fn" rid="TN1"><sup>A</sup></xref></td>
<td valign="top" align="center"><bold>4.5 (4.2</bold>&#x02013;<bold>4.7)</bold><xref ref-type="table-fn" rid="TN1"><sup>A</sup></xref></td>
<td valign="top" align="center">4.8 (4.2&#x02013;5.5)</td>
<td valign="top" align="center"><bold>3.3 (2.3</bold>&#x02013;<bold>4.3)</bold><xref ref-type="table-fn" rid="TN1"><sup>A</sup></xref>, <xref ref-type="table-fn" rid="TN1"><sup>G</sup></xref></td>
<td valign="top" align="center">5.4 (4.5&#x02013;6.3)</td>
<td valign="top" align="center"><bold>6.4 (5.3</bold>&#x02013;<bold>7.4)</bold><xref ref-type="table-fn" rid="TN5"><sup>E</sup></xref></td>
</tr>
<tr>
<td valign="top" align="left">Testing of suspected cases</td>
<td valign="top" align="center"><bold>4.5 (4.0</bold>&#x02013;<bold>5.0)</bold><xref ref-type="table-fn" rid="TN2"><sup>B</sup></xref>, <xref ref-type="table-fn" rid="TN4"><sup>D</sup></xref>, <xref ref-type="table-fn" rid="TN5"><sup>E</sup></xref></td>
<td valign="top" align="center"><bold>2.4 (1.9</bold>&#x02013;<bold>3.0)</bold><xref ref-type="table-fn" rid="TN1"><sup>A</sup></xref>, <xref ref-type="table-fn" rid="TN3"><sup>C</sup></xref>, <xref ref-type="table-fn" rid="TN6"><sup>F</sup></xref>, <xref ref-type="table-fn" rid="TN1"><sup>G</sup></xref></td>
<td valign="top" align="center"><bold>3.9 (3.7</bold>&#x02013;<bold>4.1)</bold><xref ref-type="table-fn" rid="TN2"><sup>B</sup></xref>, <xref ref-type="table-fn" rid="TN4"><sup>D</sup></xref>, <xref ref-type="table-fn" rid="TN5"><sup>E</sup></xref></td>
<td valign="top" align="center"><bold>2.6 (2.1</bold>&#x02013;<bold>3.1)</bold><xref ref-type="table-fn" rid="TN1"><sup>A</sup></xref>, <xref ref-type="table-fn" rid="TN3"><sup>C</sup></xref>, <xref ref-type="table-fn" rid="TN6"><sup>F</sup></xref>, <xref ref-type="table-fn" rid="TN1"><sup>G</sup></xref></td>
<td valign="top" align="center"><bold>1.9 (1.1</bold>&#x02013;<bold>2.7)</bold><xref ref-type="table-fn" rid="TN1"><sup>A</sup></xref>, <xref ref-type="table-fn" rid="TN3"><sup>C</sup></xref>, <xref ref-type="table-fn" rid="TN6"><sup>F</sup></xref>, <xref ref-type="table-fn" rid="TN1"><sup>G</sup></xref></td>
<td valign="top" align="center"><bold>5.1 (4.4</bold>&#x02013;<bold>5.8)</bold><xref ref-type="table-fn" rid="TN2"><sup>B</sup></xref>, <xref ref-type="table-fn" rid="TN4"><sup>D</sup></xref>, <xref ref-type="table-fn" rid="TN5"><sup>E</sup></xref></td>
<td valign="top" align="center"><bold>5.2 (4.4</bold>&#x02013;<bold>6.1)</bold><xref ref-type="table-fn" rid="TN2"><sup>B</sup></xref>, <xref ref-type="table-fn" rid="TN4"><sup>D</sup></xref>, <xref ref-type="table-fn" rid="TN5"><sup>E</sup></xref></td>
</tr>
<tr>
<td valign="top" align="left">Preparedness for a pandemic</td>
<td valign="top" align="center"><bold>4.3 (3.8</bold>&#x02013;<bold>4.9)</bold><xref ref-type="table-fn" rid="TN2"><sup>B</sup></xref>, <xref ref-type="table-fn" rid="TN3"><sup>C</sup></xref>, <xref ref-type="table-fn" rid="TN5"><sup>E</sup></xref></td>
<td valign="top" align="center"><bold>2.7 (2.1</bold>&#x02013;<bold>3.4)</bold><xref ref-type="table-fn" rid="TN1"><sup>A</sup></xref></td>
<td valign="top" align="center"><bold>3.0 (2.8</bold>&#x02013;<bold>3.3)</bold><xref ref-type="table-fn" rid="TN1"><sup>A</sup></xref></td>
<td valign="top" align="center">3.9 (3.3&#x02013;4.5)</td>
<td valign="top" align="center"><bold>2.4 (1.5</bold>&#x02013;<bold>3.3)</bold><xref ref-type="table-fn" rid="TN1"><sup>A</sup></xref></td>
<td valign="top" align="center">3.8 (3.0&#x02013;4.6)</td>
<td valign="top" align="center">4.1 (3.1&#x02013;5.1)</td>
</tr>
<tr>
<td valign="top" align="left">Protection of staff</td>
<td valign="top" align="center">2.9 (2.3&#x02013;3.5)</td>
<td valign="top" align="center">2.0 (1.4&#x02013;2.7)</td>
<td valign="top" align="center">2.0 (1.7&#x02013;2.2)</td>
<td valign="top" align="center">2.7 (2.1&#x02013;3.3)</td>
<td valign="top" align="center">2.2 (1.2&#x02013;3.1)</td>
<td valign="top" align="center">2.2 (1.4&#x02013;3.1)</td>
<td valign="top" align="center">1.2 (0.1&#x02013;2.2)</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="TN1"><label>A</label><p><italic>post-hoc</italic> comparison to Australia, <italic>p</italic> &#x0003C; 0.05 (Bonferroni corrected).</p></fn>
<fn id="TN2"><label>B</label><p><italic>post-hoc</italic> comparison to Austria, <italic>p</italic> &#x0003C; 0.05 (Bonferroni corrected).</p></fn>
<fn id="TN3"><label>C</label><p><italic>post-hoc</italic> comparison to Germany, <italic>p</italic> &#x0003C; 0.05 (Bonferroni corrected).</p></fn>
<fn id="TN4"><label>D</label><p><italic>post-hoc</italic> comparison to Hungary, <italic>p</italic> &#x0003C; 0.05 (Bonferroni corrected).</p></fn>
<fn id="TN5"><label>E</label><p><italic>post-hoc</italic> comparison to Italy, <italic>p</italic> &#x0003C; 0.05 (Bonferroni corrected).</p></fn>
<fn id="TN6"><label>F</label><p><italic>post-hoc</italic> comparison to Slovenia, <italic>p</italic> &#x0003C; 0.05 (Bonferroni corrected).</p></fn>
<fn id="TN7"><label>G</label><p><italic>post-hoc</italic> comparison to Switzerland, <italic>p</italic> &#x0003C; 0.05 (Bonferroni corrected).</p></fn>
<p>Significant differences are in bold (Scale values range from 0 to 10).</p>
</table-wrap-foot>
</table-wrap>
<fig id="F1" position="float">
<label>Figure 1</label>
<caption><p>Scale values for each country (dashed black line: overall mean).</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fpubh-10-1072515-g0001.tif"/>
</fig></sec>
<sec>
<title>Provision of information to GPs</title>
<p>Swiss GPs rated the provision of information to GPs (6.4, 95% CI 5.3&#x02013;7.4) more highly than Italian GPs (3.3, 95% CI 2.3&#x02013;4.3, <italic>p</italic> = 0.006). The biggest difference in their evaluations was in whether the guidelines on how to deal with suspected cases of COVID-19 were sufficiently detailed (CH: 87.3 vs. IT: 32.4%). Australian GPs rated the provision of information to GPs (5.9, 95% CI 5.3&#x02013;6.5) more highly than Italian (<italic>p</italic> = 0.001), Austrian (4.2, 95% CI 3.5&#x02013;4.9, <italic>p</italic> = 0.018) and German (4.5, 95% CI 4.2&#x02013;4.7, <italic>p</italic> = 0.002) GPs. Between Australian and Italian GPs, the biggest difference in the evaluation was whether they had received guidelines on how to deal with suspected cases of COVID-19 in a timely manner (AU:84.8 vs. IT: 33.8%).</p></sec>
<sec>
<title>Testing of suspected cases</title>
<p>Differences in the evaluation of the effort expended on testing suspected cases varied substantially between countries. Italian (1.9, 95% CI 1.1&#x02013;2.7), Austrian (2.4, 95% CI 1.9&#x02013;3.0) and Hungarian (2.6, 95% CI 2.1&#x02013;2.7). GPs rated the effort expended on testing suspected cases as significantly lower (<italic>p</italic> &#x0003C; 0.001) than did German (3.9, 95% CI 3.7&#x02013;4.1), Australian (4.5, 95% CI 4.0&#x02013;5.0), Slovenian (5.1, 95% CI 4.4&#x02013;5.8) and Swiss (5.2, 95% CI 4.4&#x02013;6.1) GPs. On an item level, 92.6% of Italian and 82.7% of Austrian GPs but only 12.9% of Slovenian GPs thought the number of tests that were conducted was insufficient. Furthermore, 10.1% of Austrian and 5.9% of Italian GPs but 81.0% of the Slovenian GPs said that they had adequate access to tests from the beginning of the COVID-19 pandemic.</p></sec>
<sec>
<title>Preparedness for a pandemic</title>
<p>Australian GPs rated their preparedness for a pandemic (4.3, 95% CI 3.8&#x02013;4.9) higher than German (3.0, 95% CI 2.8&#x02013;3.3, <italic>p</italic> = 0.003) Austrian (2.7, 95% CI 2.1&#x02013;3.4, <italic>p</italic> = 0.020), and Italian GPs (2.4, 95% CI 1.5&#x02013;3.3, <italic>p</italic> = 0.049). Big differences between Australian and German, Austrian and Italian GPs were found in how they rated the preparedness of their practices to face a pandemic (AU: 43.8, AT: 23.1, DE: 23.3, IT: 27.3%), and whether they had sufficient information on how much protective equipment they would need (AU: 26.8, AT: 8.0, DE: 9.3, IT: 14.9%).</p></sec>
<sec>
<title>Protection of staff</title>
<p>No differences between countries were found in GPs&#x00027; effort to protect staff.</p></sec></sec></sec>
<sec sec-type="discussion" id="s4">
<title>Discussion</title>
<sec>
<title>Overall results</title>
<p>Our 2020 survey of over 1,600 general practitioners from seven countries revealed that GPs generally had considerable self-confidence and went to great efforts to control the spread of the COVID-19 pandemic. In the first stages, GPs in Europe and Australia were not well prepared to face a pandemic, had to confront a fall in the number of patient contacts and had to make do with unsatisfactory testing procedures for suspected cases. GPs regarded the risks of the pandemic as moderate, but only received limited information from health care authorities on how to deal with suspected cases of COVID-19. Between the various countries, the responses of the GPs differed in all dimensions except for the protection of staff, which was consistently low. Differences are understandable as GPs have to deal with the specific challenges of acting within the primary health care system of their own country (<xref ref-type="bibr" rid="B7">7</xref>, <xref ref-type="bibr" rid="B17">17</xref>&#x02013;<xref ref-type="bibr" rid="B25">25</xref>).</p></sec>
<sec>
<title>Preparedness to face a pandemic</title>
<p>In accordance with other previously published papers, the highest scores in preparedness to face a pandemic were observed in Australia (<xref ref-type="bibr" rid="B22">22</xref>), and the lowest scores in Italy (<xref ref-type="bibr" rid="B20">20</xref>). While in Australia, the role of GPs during a pandemic has been discussed in scientific papers for a long time (<xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B27">27</xref>), the topic in central Europe was only a minor issue before the outbreak of COVID-19. As early as 2006, Shaw (<xref ref-type="bibr" rid="B28">28</xref>) said it was important that Australian GPs were in a position to continue working effectively during a pandemic, adding that to be able to do this, it was essential that they receive appropriate education, training and equipment. Furthermore, Australian experts discussed how important it is that GPs participate in surveillance systems to identify clusters, and are involved in adapting the system in preparation for a pandemic in good time (<xref ref-type="bibr" rid="B29">29</xref>, <xref ref-type="bibr" rid="B30">30</xref>). In Europe, the role GPs might play in a pandemic was discussed in several countries [e.g., the Netherlands (<xref ref-type="bibr" rid="B31">31</xref>), Great Britain (<xref ref-type="bibr" rid="B32">32</xref>), Germany (<xref ref-type="bibr" rid="B33">33</xref>) and Hungry (<xref ref-type="bibr" rid="B34">34</xref>)]. However, this research activity in Europe was limited to isolated publications. As Xiao et al. pointed out, not only the appropriate education and training for pandemic situations, but also the general education for GPs is in crucial aspect of preparedness (<xref ref-type="bibr" rid="B35">35</xref>).</p>
<p>Pandemic preparedness is a global issue. One year before the outbreak of COVID-19, Gupta et al. recognized that many countries were not adequately prepared to face a pandemic (<xref ref-type="bibr" rid="B36">36</xref>). More than 50% of countries scored inadequately in terms of almost 90% of the indicators used to gauge preparedness for outbreaks of infectious diseases. Oppenheimer et al. also found that many countries were not prepared for a pandemic (<xref ref-type="bibr" rid="B37">37</xref>). Furthermore, both studies found that an association existed between preparedness and the economic strength of a country. Therefore, countries in Europe and North America were most prepared and independent of region a higher GDP per capita, more public health expenditures as a percentage of GDP and higher density of skilled health professionals per 10.000 persons were associated with a better preparedness (<xref ref-type="bibr" rid="B36">36</xref>, <xref ref-type="bibr" rid="B37">37</xref>).</p></sec>
<sec>
<title>Self-confidence and perception of risk</title>
<p>Self-confidence, or the belief in one&#x00027;s ability to successfully accomplish specific goals, and perception of risk, both play an important role in GPs&#x00027; professional and private lives. We could observe differences between GPs in different countries in terms of both risk perception and self-confidence. Similar results for COVID-19 risk perceptions have already been reported for overall populations, and among health care workers and GPs (<xref ref-type="bibr" rid="B38">38</xref>, <xref ref-type="bibr" rid="B39">39</xref>). Furthermore, it is not only the overall level of risk perception that differs between countries, but also the predictors of risk perceptions. While political ideology was an important predictor of COVID-19 risk perceptions in South Korea and the United States, social amplification was significantly more important in Australia, Germany, Spain, Japan, Sweden and the United Kingdom (<xref ref-type="bibr" rid="B39">39</xref>, <xref ref-type="bibr" rid="B40">40</xref>). It is also interesting that COVID-19 risk perceptions are not associated with local epidemic severity (<xref ref-type="bibr" rid="B38">38</xref>). Risk perceptions are, however, an important predictor of self-confidence (<xref ref-type="bibr" rid="B40">40</xref>). In GPs and health care workers, it was found that a higher level of confidence is associated with lower levels of emotional exhaustion, anxiety in general, COVID-19 anxiety, and concerns about one&#x00027;s family, as well as with higher levels of self-perceived preparedness (<xref ref-type="bibr" rid="B41">41</xref>&#x02013;<xref ref-type="bibr" rid="B43">43</xref>). On the other hand, such aspects as social support and quality of sleep, and pre-crisis education and training programmes, can also increase self-confidence (<xref ref-type="bibr" rid="B44">44</xref>, <xref ref-type="bibr" rid="B45">45</xref>).</p></sec>
<sec>
<title>Decrease in numbers</title>
<p>The provision of primary healthcare services decreased in all countries, and especially in Germany and Austria, where GPs said that many patients avoided coming to the practice. In Switzerland and Australia, the number of patient contacts decreased the least. Drawing on data from over 80 million visits in 2019 and 2020, the INTernational ConsoRtium of Primary Care BIg Data Researchers (INTRePID) confirmed that a fall in patient contacts was a global phenomenon. Nevertheless, primary care physician consultations remained stable in Australia (<xref ref-type="bibr" rid="B19">19</xref>). One longitudinal observational study from Germany comparing the pre- COVID period with April&#x02013;July 2020 described a significant decrease in GP consultations per week for conditions relating to the total and upper gastrointestinal tract, vertigo, spinal disorders, general fatigue and weakness, as well as in 12 further services (house calls, stool tests, referrals to a specialist, check-up 35, urine analysis, pain therapy, skin cancer screening, electrocardiograms, blood tests, pulmonary function tests, sonography, and wound management) (<xref ref-type="bibr" rid="B25">25</xref>). A decline in practice visits was accompanied by a clear shift to telemedicine appointments, as highlighted in a narrative review published by Kichloo et al. (<xref ref-type="bibr" rid="B46">46</xref>). The number of telemedicine appointments was particularly high at the beginning of the pandemic, but decreased later (<xref ref-type="bibr" rid="B16">16</xref>).</p></sec>
<sec>
<title>Provision of information</title>
<p>GPs in Switzerland and Australia rated the amount of information they had been provided with more highly than other countries, which is probably because they received guidelines on how to deal with suspected COVID-19 cases earlier (<xref ref-type="supplementary-material" rid="SM1">Supplementary Table S1</xref>). As in Switzerland and Australia, Slovenian GPs also appear to have enjoyed a more productive exchange of information with health authorities than other countries. Nevertheless, the majority of GPs in our study said that information was available on public media before it was officially provided by official institutions such as health insurers. The problem of inadequate communication with the health authorities was described in an Australian publication as soon as 2015 (<xref ref-type="bibr" rid="B27">27</xref>), and further confirmed by Rawaf et al., who concluded from a worldwide survey that primary care professionals were poorly informed by policymakers (<xref ref-type="bibr" rid="B47">47</xref>). As insufficient information was available from public stakeholders, many GPs creatively established and used regional networks to share information during the first phase of the COVID-19 pandemic (<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B18">18</xref>, <xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B24">24</xref>, <xref ref-type="bibr" rid="B47">47</xref>).</p></sec>
<sec>
<title>Testing of suspected cases</title>
<p>The availability of diagnostic COVID-19 testing varied substantially across countries. Our analyses revealed that GPs from Italy, Hungary and Austria said that in the early stages, access to laboratory testing for COVID-19 in GPs practices was inadequate and rarely carried out. These GPs increasingly demanded that they should be permitted to decide who should be tested and who should not (see <xref ref-type="supplementary-material" rid="SM1">Supplementary Table S1</xref>). Since there are differences between countries in the number of tests per million inhabitants, it is to be expected that the GPs assessments would vary (<xref ref-type="bibr" rid="B48">48</xref>). The number of tests not only differed between countries, but also developed very differently over time (<xref ref-type="bibr" rid="B48">48</xref>). It should be kept in mind that our survey was conducted before routine diagnostic COVID-19 testing was available, i.e., only PCR testing was possible and rapid antigen screening tests did not exist. Circumstances have therefore changed substantially, and there appears to no longer be any shortage of test kits in the countries under review.</p></sec>
<sec>
<title>Protection of staff</title>
<p>GPs in our survey complained that they could not protect their staff, but such complaints were not only heard from GPs, with the British Medical Association, for example, also warning that doctors were at &#x0201C;considerable&#x0201D; risk due to a lack of personal protective equipment (<xref ref-type="bibr" rid="B49">49</xref>, <xref ref-type="bibr" rid="B50">50</xref>). Furthermore, the Global Forum on Universal Health Coverage and Primary Health Care, which represents 29 countries, also said they were insufficiently equipped to provide care to protect staff (<xref ref-type="bibr" rid="B47">47</xref>). In contrast, a survey of 361 Chinese GPs (of whom 54 worked in hospitals) (<xref ref-type="bibr" rid="B43">43</xref>) found that GPs were overall well-equipped and supported during the outbreak of the COVID-19 pandemic, particularly in large Chinese cities. In order to deal with the virus, nearly all clinics provided training and seminars, and gave talks, not only to healthcare workers but also to the general public. Almost all GPs provided information to their patients during consultations, on social media and the telephone, and by means of posters and leaflets in clinics. However, despite all these efforts, only 15% of hospital GPs thought their clinic provided sufficient support to protect staff.</p></sec>
<sec>
<title>Strengths and limitations</title>
<p>Our study has some limitations. Firstly, the questionnaire was developed in a very short time in order that it could be answered when the situation was most acute. Even though we tried to include all relevant topics, some issues may therefore have been missed. Secondly, we could not calculate the response rate because a systematic area-wide survey was not possible in the time frame we permitted ourselves. Nevertheless, the number of responses far exceeded our expectations, especially considering the difficulties that are usually encountered in recruiting GPs for research. Thirdly, as the recruitment process was conducted through regional networks and professional associations, the participants may not have been representative of GPs as a whole. Fourthly, we know that online surveys are not as suitable for the collection of in-depth information as interviews. Fifth, this cross-sectional survey was carried out in the first half of 2020, since when many changes have occurred in pandemic management. For this reason, we also carried out a longitudinal survey in Germany and Austria, which revealed that physicians in primary care have adapted quickly to new situations and have gained experience in telemedicine, enabling them to overcome changes in the delivery of routine health care (<xref ref-type="bibr" rid="B16">16</xref>). Despite involving seven countries, our study was not truly representative. However, the PRICOV-19 study that is being carried out in 37 European countries and Israel is currently ongoing and should provide more information on how GP practices have functioned during the COVID-19 pandemic on a European level (<xref ref-type="bibr" rid="B51">51</xref>). One further limitation is that our survey was only carried out among GPs and did not involve other team members from a primary care setting. Nevertheless, the study succeeded in providing an insight into the challenges of providing care in the early stages of the pandemic in a wide range of countries, and it identifies substantial differences between them. A further limitation is that sample sizes vary between countries. These unbalanced sample sizes may have an impact on the results.</p>
<p>Last but not least, the questionnaire was used in different languages. It cannot therefore be ruled out that differences between countries reflect discrepancies in the translation. We used differential item functioning (DIF) to investigate the extent of any discrepancies. This analysis investigates whether GPs from different groups (e.g., countries; pairwise comparisons) that are being assessed using the same scales (e.g., self-confidence) answer individual items in a similar way. The analysis revealed that on two scales (self-confidence, preparedness) and 16 further items, no DIF could be found, while only one DIF was found in 6 out of 39 investigated items. Since the number of DIFs is comparable in countries where the same language is spoken (e.g., Austria &#x02013; Germany: <italic>n</italic> = 4; Switzerland- Germany: <italic>n</italic> = 4) and countries using different languages (e.g., Australia&#x02013;Germany: <italic>n</italic> = 3), the DIFs are assumed to be due to aspects other than language (e.g., differences in primary health care systems). The highest number of DIFs could be observed in a comparison between Germany and Slovenia (<italic>n</italic> = 8) (<xref ref-type="supplementary-material" rid="SM2">Supplementary Table S2</xref>).</p></sec></sec>
<sec sec-type="conclusions" id="s5">
<title>Conclusion</title>
<p>Although general practitioners in different countries were confronted with the same pandemic, its impact differed in a number of aspects (e.g., self-confidence, perception of risk). To some extent this may be because countries presumably had different levels of experiences regarding prior pandemics and therefore in how well-prepared they were to face them. This, in turn, may have been reflected in differences in the provision of information and equipment to GPs. Differences in health care systems between the countries may also have had an impact. Knowledge of these differences is important and should be shared in order to be better prepared for future pandemics. It is also essential that primary care representatives are involved in the preparation of structured care plans for future infectious diseases at an early stage.</p>
<p><bold>Question:</bold> Are there differences regarding management and personal experience of general practitioners in seven countries at the beginning of the COVID-19 pandemics?</p>
<p><bold>Finding:</bold> Despite facing the same pandemic, there was substantial variation in almost all evaluated dimensions, for which differences in health care systems and experiences with recent pandemics may be responsible.</p>
<p><bold>Meaning:</bold> GPs should be involved in developing a coordinated strategy to deal with pandemics, which should be communicated to affected health care institutions and populations as early as possible.</p></sec>
<sec id="s6">
<title>Reproducible research statement</title>
<p><italic>Study protocol:</italic> Detailed information is provided in the Supplement of the Siebenhofer et al. (<xref ref-type="bibr" rid="B13">13</xref>). <italic>Data set:</italic> Available from AA, PhD (<email>alexander.avian&#x00040;medunigraz.at</email>).</p></sec>
<sec sec-type="data-availability" id="s7">
<title>Data availability statement</title>
<p>The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.</p></sec>
<sec id="s8">
<title>Ethics statement</title>
<p>The studies involving human participants were reviewed and approved by Ethics Committee of Bond University, Australia (AS200424). Ethics Committee of Goethe University Frankfurt, Germany (ID 20-619). Written informed consent for participation was not required for this study in accordance with the national legislation and the institutional requirements.</p></sec>
<sec id="s9">
<title>Author contributions</title>
<p>Conceptualization: ASi, AA, DS-S, KM, SH, HB, MF, ASc, and MG. Data curation: SH and AA. Formal analysis and visualization: AA. Investigation: AA, SH, ASc, AT, EZ, AM, GP, SS, KJ, DS-S, KM, HB, MF, ASi, and MG. Methodology: AA, HB, MF, and ASi. Project administration: DS-S, KM, SH, MF, and ASi. Resources: ASi and KM. Supervision: ASi and MF. Writing&#x02014;original draft: AA, ASc, ASi, and MG. Writing&#x02014;review and editing: AT, EZ, AM, GP, SS, KJ, DS-S, KM, AA, SH, HB, MF, ASi, and MG. All authors contributed to the article and approved the submitted version.</p>
</sec>
<sec sec-type="COI-statement" id="conf1">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p></sec>
<sec sec-type="disclaimer" id="s10">
<title>Publisher&#x00027;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p></sec>
</body>
<back>
<ack><p>We would like to thank all participating general practitioners and the institutions that were willing to send the link to our questionnaire to their network partners.</p>
</ack>
<sec sec-type="supplementary-material" id="s11">
<title>Supplementary material</title>
<p>The Supplementary Material for this article can be found online at: <ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/fpubh.2022.1072515/full#supplementary-material">https://www.frontiersin.org/articles/10.3389/fpubh.2022.1072515/full#supplementary-material</ext-link></p>
<supplementary-material xlink:href="Table_1.DOCX" id="SM1" mimetype="application/vnd.openxmlformats-officedocument.wordprocessingml.document" xmlns:xlink="http://www.w3.org/1999/xlink"/>
<supplementary-material xlink:href="Table_2.DOCX" id="SM2" mimetype="application/vnd.openxmlformats-officedocument.wordprocessingml.document" xmlns:xlink="http://www.w3.org/1999/xlink"/></sec>
<ref-list>
<title>References</title>
<ref id="B1">
<label>1.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cucinotta</surname> <given-names>D</given-names></name> <name><surname>Vanelli</surname> <given-names>M</given-names></name> <name><surname>WHO</surname></name></person-group>. <article-title>Declares COVID-19 a pandemic</article-title>. <source>Acta Biomed.</source> (<year>2020</year>) <volume>91</volume>:<fpage>157</fpage>&#x02013;<lpage>60</lpage>. <pub-id pub-id-type="doi">10.23750/abm.v91i1.9397</pub-id><pub-id pub-id-type="pmid">32191675</pub-id></citation></ref>
<ref id="B2">
<label>2.</label>
<citation citation-type="web"><person-group person-group-type="author"><collab>World Health Organisation. WHO Coronavirus (COVID-19) Dashboard.</collab></person-group> (<year>2021</year>). Available online at: <ext-link ext-link-type="uri" xlink:href="https://covid19.who.int/">https://covid19.who.int/</ext-link> (accessed November 28, 2022).</citation>
</ref>
<ref id="B3">
<label>3.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Erdem</surname> <given-names>H</given-names></name> <name><surname>Lucey</surname> <given-names>DR</given-names></name></person-group>. <article-title>Healthcare worker infections and deaths due to COVID-19: a survey from 37 nations and a call for WHO to post-national data on their website</article-title>. <source>Int J Infect Dis IJID Official Publ Int Soc Infect Dis.</source> (<year>2021</year>) <volume>102</volume>:<fpage>239</fpage>&#x02013;<lpage>41</lpage>. <pub-id pub-id-type="doi">10.1016/j.ijid.2020.10.064</pub-id><pub-id pub-id-type="pmid">33130210</pub-id></citation></ref>
<ref id="B4">
<label>4.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Moynihan</surname> <given-names>R</given-names></name> <name><surname>Sanders</surname> <given-names>S</given-names></name> <name><surname>Michaleff</surname> <given-names>ZA</given-names></name> <name><surname>Scott</surname> <given-names>AM</given-names></name> <name><surname>Clark</surname> <given-names>J</given-names></name> <name><surname>To</surname> <given-names>EJ</given-names></name> <etal/></person-group>. <article-title>Impact of COVID-19 pandemic on utilisation of healthcare services: a systematic review</article-title>. <source>BMJ Open.</source> (<year>2021</year>) <volume>11</volume>:<fpage>e045343</fpage>. <pub-id pub-id-type="doi">10.1136/bmjopen-2020-045343</pub-id><pub-id pub-id-type="pmid">33727273</pub-id></citation></ref>
<ref id="B5">
<label>5.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Lasalvia</surname> <given-names>A</given-names></name> <name><surname>Rigon</surname> <given-names>G</given-names></name> <name><surname>Rugiu</surname> <given-names>C</given-names></name> <name><surname>Negri</surname> <given-names>C</given-names></name> <name><surname>Del Zotti</surname> <given-names>F</given-names></name> <name><surname>Amaddeo</surname> <given-names>F</given-names></name> <etal/></person-group>. <article-title>The psychological impact of COVID-19 among primary care physicians in the province of Verona, Italy: a cross-sectional study during the first pandemic wave</article-title>. <source>Fam Pract.</source> (<year>2021</year>) <volume>39</volume>:<fpage>65</fpage>&#x02013;<lpage>73</lpage>. <pub-id pub-id-type="doi">10.1093/fampra/cmab106</pub-id><pub-id pub-id-type="pmid">34482406</pub-id></citation></ref>
<ref id="B6">
<label>6.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Lim</surname> <given-names>J</given-names></name> <name><surname>Broughan</surname> <given-names>J</given-names></name> <name><surname>Crowley</surname> <given-names>D</given-names></name> <name><surname>O&#x00027;Kelly</surname> <given-names>B</given-names></name> <name><surname>Fawsitt</surname> <given-names>R</given-names></name> <name><surname>Burke</surname> <given-names>MC</given-names></name> <etal/></person-group>. <article-title>COVID-19&#x00027;s impact on primary care and related mitigation strategies: a scoping review</article-title>. <source>Eur J Gen Pract.</source> (<year>2021</year>) <volume>27</volume>:<fpage>166</fpage>&#x02013;<lpage>75</lpage>. <pub-id pub-id-type="doi">10.1080/13814788.2021.1946681</pub-id><pub-id pub-id-type="pmid">34282695</pub-id></citation></ref>
<ref id="B7">
<label>7.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Huston</surname> <given-names>P</given-names></name> <name><surname>Campbell</surname> <given-names>J</given-names></name> <name><surname>Russell</surname> <given-names>G</given-names></name> <name><surname>Goodyear-Smith</surname> <given-names>F</given-names></name> <name><surname>Phillips</surname> <given-names>RL</given-names></name> <name><surname>van Weel</surname> <given-names>C</given-names></name> <etal/></person-group>. <article-title>COVID-19 and primary care in six countries</article-title>. <source>BJGP Open</source>. (<year>2020</year>) <volume>4</volume>:<fpage>4</fpage>. <pub-id pub-id-type="doi">10.3399/bjgpopen20X101128</pub-id><pub-id pub-id-type="pmid">34319893</pub-id></citation></ref>
<ref id="B8">
<label>8.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mughal</surname> <given-names>F</given-names></name> <name><surname>Khunti</surname> <given-names>K</given-names></name> <name><surname>Mallen</surname> <given-names>CD</given-names></name></person-group>. <article-title>The impact of COVID-19 on primary care: insights from the national health service (NHS) and future recommendations</article-title>. <source>J Family Med Prim Care.</source> (<year>2021</year>) <volume>10</volume>:<fpage>4345</fpage>. <pub-id pub-id-type="doi">10.4103/jfmpc.jfmpc_756_21</pub-id><pub-id pub-id-type="pmid">35165652</pub-id></citation></ref>
<ref id="B9">
<label>9.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mughal</surname> <given-names>F</given-names></name> <name><surname>Mallen</surname> <given-names>CD</given-names></name> <name><surname>McKee</surname> <given-names>M</given-names></name></person-group>. <article-title>The impact of COVID-19 on primary care in Europe</article-title>. <source>Lancet Reg Health Eur.</source> (<year>2021</year>) <volume>6</volume>:<fpage>100152</fpage>. <pub-id pub-id-type="doi">10.1016/j.lanepe.2021.100152</pub-id><pub-id pub-id-type="pmid">34226894</pub-id></citation></ref>
<ref id="B10">
<label>10.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Verhoeven</surname> <given-names>V</given-names></name> <name><surname>Tsakitzidis</surname> <given-names>G</given-names></name> <name><surname>Philips</surname> <given-names>H</given-names></name> <name><surname>Van Royen</surname> <given-names>P</given-names></name></person-group>. <article-title>Impact of the COVID-19 pandemic on the core functions of primary care: will the cure be worse than the disease? A qualitative interview study in flemish GPs</article-title>. <source>BMJ Open.</source> (<year>2020</year>) <volume>10</volume>:<fpage>e039674</fpage>. <pub-id pub-id-type="doi">10.1136/bmjopen-2020-039674</pub-id><pub-id pub-id-type="pmid">32554730</pub-id></citation></ref>
<ref id="B11">
<label>11.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Chudasama</surname> <given-names>YV</given-names></name> <name><surname>Gillies</surname> <given-names>CL</given-names></name> <name><surname>Zaccardi</surname> <given-names>F</given-names></name> <name><surname>Coles</surname> <given-names>B</given-names></name> <name><surname>Davies</surname> <given-names>MJ</given-names></name> <name><surname>Seidu</surname> <given-names>S</given-names></name> <etal/></person-group>. <article-title>Impact of COVID-19 on routine care for chronic diseases: a global survey of views from healthcare professionals</article-title>. <source>Diabetes Metab Syndr.</source> (<year>2020</year>) <volume>14</volume>:<fpage>965</fpage>&#x02013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1016/j.dsx.2020.06.042</pub-id><pub-id pub-id-type="pmid">32604016</pub-id></citation></ref>
<ref id="B12">
<label>12.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mayo</surname> <given-names>M</given-names></name> <name><surname>Potugari</surname> <given-names>B</given-names></name> <name><surname>Bzeih</surname> <given-names>R</given-names></name> <name><surname>Scheidel</surname> <given-names>C</given-names></name> <name><surname>Carrera</surname> <given-names>C</given-names></name> <name><surname>Shellenberger</surname> <given-names>RA</given-names></name></person-group>. <article-title>Cancer screening during the COVID-19 pandemic: a systematic review and meta-analysis</article-title>. <source>Mayo Clin Proc Innov Qual Outcomes.</source> (<year>2021</year>) <volume>5</volume>:<fpage>1109</fpage>&#x02013;<lpage>17</lpage>. <pub-id pub-id-type="doi">10.1016/j.mayocpiqo.2021.10.003</pub-id><pub-id pub-id-type="pmid">34693211</pub-id></citation></ref>
<ref id="B13">
<label>13.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Siebenhofer</surname> <given-names>A</given-names></name> <name><surname>Huter</surname> <given-names>S</given-names></name> <name><surname>Avian</surname> <given-names>A</given-names></name> <name><surname>Mergenthal</surname> <given-names>K</given-names></name> <name><surname>Schaffler-Schaden</surname> <given-names>D</given-names></name> <name><surname>Spary-Kainz</surname> <given-names>U</given-names></name> <etal/></person-group>. <article-title>COVI-Prim survey: challenges for Austrian and German general practitioners during initial phase of COVID-19</article-title>. <source>PLoS ONE.</source> (<year>2021</year>) <volume>16</volume>:<fpage>e0251736</fpage>. <pub-id pub-id-type="doi">10.1371/journal.pone.0251736</pub-id><pub-id pub-id-type="pmid">34111120</pub-id></citation></ref>
<ref id="B14">
<label>14.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Eysenbach</surname> <given-names>G</given-names></name></person-group>. <article-title>Improving the quality of web surveys: the checklist for reporting results of internet E-surveys (CHERRIES)</article-title>. <source>J Med Internet Res.</source> (<year>2004</year>) <volume>6</volume>:<fpage>e34</fpage>. <pub-id pub-id-type="doi">10.2196/jmir.6.3.e34</pub-id><pub-id pub-id-type="pmid">31060751</pub-id></citation></ref>
<ref id="B15">
<label>15.</label>
<citation citation-type="web"><person-group person-group-type="author"><collab>German Clinical Trials Register (DRKS) [Internet] Cologne(MD): Cologne(MD): Federal Institute for Drugs and Medical Devices (BfArM) within the scope of the Federal Ministry of Health (BMG) (Germany)</collab></person-group>. <article-title>2008-Oct</article-title>. <source>Identifier DRKS00021231, Accompanying Monitoring of Primary Care in GP Practices During the COVID-19 Pandemic (COVIPRIM).</source> (<year>2020</year>). Available online at: <ext-link ext-link-type="uri" xlink:href="https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&#x00026;TRIAL_ID=DRKS00021231">https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&#x00026;TRIAL_ID=DRKS00021231</ext-link> (accessed Jun 27, 2022).</citation>
</ref>
<ref id="B16">
<label>16.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Schaffler-Schaden</surname> <given-names>D</given-names></name> <name><surname>Mergenthal</surname> <given-names>K</given-names></name> <name><surname>Avian</surname> <given-names>A</given-names></name> <name><surname>Huter</surname> <given-names>S</given-names></name> <name><surname>Spary-Kainz</surname> <given-names>U</given-names></name> <name><surname>Bachler</surname> <given-names>H</given-names></name> <etal/></person-group>. <article-title>COVI-prim longitudinal survey: experiences of primary care physicians during the early phase of the COVID-19 pandemic</article-title>. <source>Front Med</source>. (<year>2022</year>) <volume>9</volume>:<fpage>365</fpage>. <pub-id pub-id-type="doi">10.3389/fmed.2022.761283</pub-id><pub-id pub-id-type="pmid">35265636</pub-id></citation></ref>
<ref id="B17">
<label>17.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wanat</surname> <given-names>M</given-names></name> <name><surname>Hoste</surname> <given-names>M</given-names></name> <name><surname>Gobat</surname> <given-names>N</given-names></name> <name><surname>Anastasaki</surname> <given-names>M</given-names></name> <name><surname>B&#x000F6;hmer</surname> <given-names>F</given-names></name> <name><surname>Chlabicz</surname> <given-names>S</given-names></name> <etal/></person-group>. <article-title>Transformation of primary care during the COVID-19 pandemic: experiences of healthcare professionals in eight European countries</article-title>. <source>Br J General Practice.</source> (<year>2021</year>) <volume>71</volume>:<fpage>e634</fpage>&#x02013;<lpage>e42</lpage>. <pub-id pub-id-type="doi">10.3399/BJGP.2020.1112</pub-id><pub-id pub-id-type="pmid">33979303</pub-id></citation></ref>
<ref id="B18">
<label>18.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cohidon</surname> <given-names>C</given-names></name> <name><surname>El Hakmaoui</surname> <given-names>F</given-names></name> <name><surname>Senn</surname> <given-names>N</given-names></name></person-group>. <article-title>The role of general practitioners in managing the COVID-19 pandemic in a private healthcare system</article-title>. <source>Fam Pract.</source> (<year>2021</year>) <volume>4</volume>:<fpage>586</fpage>&#x02013;<lpage>91</lpage>. <pub-id pub-id-type="doi">10.1093/fampra/cmab112</pub-id><pub-id pub-id-type="pmid">34537836</pub-id></citation></ref>
<ref id="B19">
<label>19.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Tu</surname> <given-names>K</given-names></name> <name><surname>Sarkadi Kristiansson</surname> <given-names>R</given-names></name> <name><surname>Gronsbell</surname> <given-names>J</given-names></name> <name><surname>de Lusignan</surname> <given-names>S</given-names></name> <name><surname>Flottorp</surname> <given-names>S</given-names></name> <name><surname>Goh</surname> <given-names>LH</given-names></name> <etal/></person-group>. <article-title>Changes in primary care visits arising from the COVID-19 pandemic: an international comparative study by the International Consortium of Primary Care Big Data Researchers (INTRePID)</article-title>. <source>BMJ Open</source>. (<year>2022</year>) <volume>12</volume>:<fpage>e059130</fpage>. <pub-id pub-id-type="doi">10.1136/bmjopen-2021-059130</pub-id><pub-id pub-id-type="pmid">35534063</pub-id></citation></ref>
<ref id="B20">
<label>20.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mahlknecht</surname> <given-names>A</given-names></name> <name><surname>Barbieri</surname> <given-names>V</given-names></name> <name><surname>Engl</surname> <given-names>A</given-names></name> <name><surname>Piccoliori</surname> <given-names>G</given-names></name> <name><surname>Wiedermann</surname> <given-names>CJ</given-names></name></person-group>. <article-title>Challenges and experiences of general practitioners during the course of the Covid-19 pandemic: a northern Italian observational study&#x02014;cross-sectional analysis and comparison of a two-time survey in primary care</article-title>. <source>Fam Pract.</source> (<year>2022</year>) <volume>39</volume>:<fpage>1009</fpage>&#x02013;<lpage>16</lpage>. <pub-id pub-id-type="doi">10.1093/fampra/cmac025</pub-id><pub-id pub-id-type="pmid">35395089</pub-id></citation></ref>
<ref id="B21">
<label>21.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kippen</surname> <given-names>R</given-names></name> <name><surname>O&#x00027;Sullivan</surname> <given-names>B</given-names></name> <name><surname>Hickson</surname> <given-names>H</given-names></name> <name><surname>Leach</surname> <given-names>M</given-names></name> <name><surname>Wallace</surname> <given-names>G</given-names></name></person-group>. <article-title>A national survey of COVID-19 challenges, responses and effects in Australian general practice</article-title>. <source>Aust J General Practice.</source> (<year>2020</year>) <volume>49</volume>:<fpage>745</fpage>&#x02013;<lpage>51</lpage>. <pub-id pub-id-type="doi">10.31128/AJGP-06-20-5465</pub-id><pub-id pub-id-type="pmid">33123716</pub-id></citation></ref>
<ref id="B22">
<label>22.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sotomayor-Castillo</surname> <given-names>C</given-names></name> <name><surname>Nahidi</surname> <given-names>S</given-names></name> <name><surname>Li</surname> <given-names>C</given-names></name> <name><surname>Hespe</surname> <given-names>C</given-names></name> <name><surname>Burns</surname> <given-names>PL</given-names></name> <name><surname>Shaban</surname> <given-names>RZ</given-names></name></person-group>. <article-title>General practitioners&#x00027; knowledge, preparedness, and experiences of managing COVID-19 in Australia</article-title>. <source>Infect Dis Health.</source> (<year>2021</year>) <volume>26</volume>:<fpage>166</fpage>&#x02013;<lpage>72</lpage>. <pub-id pub-id-type="doi">10.1016/j.idh.2021.01.004</pub-id><pub-id pub-id-type="pmid">33676878</pub-id></citation></ref>
<ref id="B23">
<label>23.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>St&#x000F6;cker</surname> <given-names>A</given-names></name> <name><surname>Demirer</surname> <given-names>I</given-names></name> <name><surname>Gunkel</surname> <given-names>S</given-names></name> <name><surname>Hoffmann</surname> <given-names>J</given-names></name> <name><surname>Mause</surname> <given-names>L</given-names></name> <name><surname>Ohnh&#x000E4;user</surname> <given-names>T</given-names></name> <etal/></person-group>. <article-title>Stockpiled personal protective equipment and knowledge of pandemic plans as predictors of perceived pandemic preparedness among German general practitioners</article-title>. <source>PLoS ONE</source>. (<year>2021</year>) <volume>16</volume>. <pub-id pub-id-type="doi">10.1371/journal.pone.0255986</pub-id><pub-id pub-id-type="pmid">34383827</pub-id></citation></ref>
<ref id="B24">
<label>24.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Eisele</surname> <given-names>M</given-names></name> <name><surname>Pohontsch</surname> <given-names>NJ</given-names></name> <name><surname>Scherer</surname> <given-names>M</given-names></name></person-group>. <article-title>Strategies in primary care to face the SARS-CoV-2/COVID-19 pandemic: an online survey</article-title>. <source>Front Med</source>. (<year>2021</year>) <volume>8</volume>:<fpage>613537</fpage>. <pub-id pub-id-type="doi">10.3389/fmed.2021.613537</pub-id><pub-id pub-id-type="pmid">34150788</pub-id></citation></ref>
<ref id="B25">
<label>25.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sch&#x000E4;fer</surname> <given-names>I</given-names></name> <name><surname>Hansen</surname> <given-names>H</given-names></name> <name><surname>Menzel</surname> <given-names>A</given-names></name> <name><surname>Eisele</surname> <given-names>M</given-names></name> <name><surname>Tajdar</surname> <given-names>D</given-names></name> <name><surname>L&#x000FC;hmann</surname> <given-names>D</given-names></name> <etal/></person-group>. <article-title>The effect of COVID-19 pandemic and lockdown on consultation numbers, consultation reasons and performed services in primary care: results of a longitudinal observational study</article-title>. <source>BMC Family Practice</source>. (<year>2021</year>) <volume>22</volume>:<fpage>1</fpage>&#x02013;<lpage>10</lpage>. <pub-id pub-id-type="doi">10.1186/s12875-021-01471-3</pub-id><pub-id pub-id-type="pmid">34162343</pub-id></citation></ref>
<ref id="B26">
<label>26.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Collins</surname> <given-names>N</given-names></name> <name><surname>Litt</surname> <given-names>J</given-names></name> <name><surname>Moore</surname> <given-names>M</given-names></name> <name><surname>Winzenberg</surname> <given-names>T</given-names></name> <name><surname>Shaw</surname> <given-names>K</given-names></name></person-group>. <article-title>General practice: professional preparation for a pandemic</article-title>. <source>Med J Aust</source>. (<year>2006</year>) <volume>185</volume>:<fpage>S66</fpage>&#x02013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.5694/j.1326-5377.2006.tb00711.x</pub-id><pub-id pub-id-type="pmid">17115956</pub-id></citation></ref>
<ref id="B27">
<label>27.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kunin</surname> <given-names>M</given-names></name> <name><surname>Engelhard</surname> <given-names>D</given-names></name> <name><surname>Thomas</surname> <given-names>S</given-names></name> <name><surname>Ashworth</surname> <given-names>M</given-names></name> <name><surname>Piterman</surname> <given-names>L</given-names></name></person-group>. <article-title>Challenges of the pandemic response in primary care during pre-vaccination period: a qualitative study</article-title>. <source>Israel J Health Policy Res</source>. (<year>2015</year>) <volume>4</volume>:<fpage>1</fpage>&#x02013;<lpage>11</lpage>. <pub-id pub-id-type="doi">10.1186/s13584-015-0028-5</pub-id><pub-id pub-id-type="pmid">26473026</pub-id></citation></ref>
<ref id="B28">
<label>28.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Shaw</surname> <given-names>KA</given-names></name></person-group>. <article-title>The GP&#x00027;s response to pandemic influenza: a qualitative study</article-title>. <source>Fam Pract.</source> (<year>2006</year>) <volume>23</volume>:<fpage>267</fpage>&#x02013;<lpage>72</lpage>. <pub-id pub-id-type="doi">10.1093/fampra/cml014</pub-id><pub-id pub-id-type="pmid">16608870</pub-id></citation></ref>
<ref id="B29">
<label>29.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Clothier</surname> <given-names>H</given-names></name> <name><surname>Turner</surname> <given-names>J</given-names></name> <name><surname>Hampson</surname> <given-names>A</given-names></name> <name><surname>Kelly</surname> <given-names>H</given-names></name></person-group>. <article-title>Geographic representativeness for sentinel influenza surveillance: implications for routine surveillance and pandemic preparedness</article-title>. <source>Aust N Z J Public Health.</source> (<year>2006</year>) <volume>30</volume>:<fpage>337</fpage>&#x02013;<lpage>41</lpage>. <pub-id pub-id-type="doi">10.1111/j.1467-842X.2006.tb00846.x</pub-id><pub-id pub-id-type="pmid">16956163</pub-id></citation></ref>
<ref id="B30">
<label>30.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Clothier</surname> <given-names>HJ</given-names></name> <name><surname>Atkin</surname> <given-names>L</given-names></name> <name><surname>Turner</surname> <given-names>J</given-names></name> <name><surname>Sundararajan</surname> <given-names>V</given-names></name> <name><surname>Kelly</surname> <given-names>HA</given-names></name> <name><surname>A</surname></name></person-group>. <article-title>comparison of data sources for the surveillance of seasonal and pandemic influenza in Victoria</article-title>. <source>Commun Dis Intell Q Rep.</source> (<year>2006</year>) <volume>30</volume>:<fpage>345</fpage>&#x02013;<lpage>9</lpage>.<pub-id pub-id-type="pmid">17120488</pub-id></citation></ref>
<ref id="B31">
<label>31.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>de Lange</surname> <given-names>MM</given-names></name> <name><surname>Meijer</surname> <given-names>A</given-names></name> <name><surname>Friesema</surname> <given-names>IH</given-names></name> <name><surname>Donker</surname> <given-names>GA</given-names></name> <name><surname>Koppeschaar</surname> <given-names>CE</given-names></name> <name><surname>Hooiveld</surname> <given-names>M</given-names></name> <etal/></person-group>. <article-title>Comparison of five influenza surveillance systems during the 2009 pandemic and their association with media attention</article-title>. <source>BMC Public Health.</source> (<year>2013</year>) <volume>13</volume>:<fpage>881</fpage>. <pub-id pub-id-type="doi">10.1186/1471-2458-13-881</pub-id><pub-id pub-id-type="pmid">24063523</pub-id></citation></ref>
<ref id="B32">
<label>32.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Beaumont</surname> <given-names>M</given-names></name> <name><surname>Duggal</surname> <given-names>HV</given-names></name> <name><surname>Mahmood</surname> <given-names>H</given-names></name> <name><surname>Olowokure</surname> <given-names>B</given-names></name> <name><surname>A</surname></name></person-group>. <article-title>survey of the preparedness for an influenza pandemic of general practitioners in the West Midlands, UK</article-title>. <source>Eur J Clin Microbiol Infect Dis.</source> (<year>2007</year>) <volume>26</volume>:<fpage>819</fpage>&#x02013;<lpage>23</lpage>. <pub-id pub-id-type="doi">10.1007/s10096-007-0377-2</pub-id><pub-id pub-id-type="pmid">17690927</pub-id></citation></ref>
<ref id="B33">
<label>33.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Eisele</surname> <given-names>M</given-names></name> <name><surname>Hansen</surname> <given-names>H</given-names></name> <name><surname>Wagner</surname> <given-names>HO</given-names></name> <name><surname>von Leitner</surname> <given-names>E</given-names></name> <name><surname>Pohontsch</surname> <given-names>N</given-names></name> <name><surname>Scherer</surname> <given-names>M</given-names></name></person-group>. <article-title>Epidemics and pandemics in general practice. What can we learn from the swine flu (H1N1) and EHEC outbreak?</article-title> <source>Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz.</source> (<year>2014</year>) <volume>57</volume>:<fpage>687</fpage>&#x02013;<lpage>93</lpage>. <pub-id pub-id-type="doi">10.1007/s00103-014-1970-z</pub-id><pub-id pub-id-type="pmid">24817143</pub-id></citation></ref>
<ref id="B34">
<label>34.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hajnal</surname> <given-names>F</given-names></name> <name><surname>Busa</surname> <given-names>C</given-names></name> <name><surname>Papp</surname> <given-names>R</given-names></name> <name><surname>Balogh</surname> <given-names>S</given-names></name></person-group>. <article-title>The role of primary care professionals in preventive activitites during epidemics. Focus group assessment of the management of flu pandemic in 2009/2010</article-title>. <source>Orv Hetil.</source> (<year>2017</year>) <volume>158</volume>:<fpage>523</fpage>&#x02013;<lpage>32</lpage>. <pub-id pub-id-type="doi">10.1556/650.2017.30627</pub-id><pub-id pub-id-type="pmid">28366081</pub-id></citation></ref>
<ref id="B35">
<label>35.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Xiao</surname> <given-names>Y</given-names></name> <name><surname>Li</surname> <given-names>Y</given-names></name> <name><surname>Du</surname> <given-names>N</given-names></name> <name><surname>Luo</surname> <given-names>L</given-names></name> <name><surname>Su</surname> <given-names>D</given-names></name></person-group>. <article-title>Challenges facing Chinese primary care in the context of COVID-19</article-title>. <source>Fam Pract</source>. (<year>2022</year>) <volume>39</volume>:<fpage>982</fpage>&#x02013;<lpage>4</lpage>. <pub-id pub-id-type="doi">10.1093/fampra/cmab179</pub-id><pub-id pub-id-type="pmid">35022689</pub-id></citation></ref>
<ref id="B36">
<label>36.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gupta</surname> <given-names>V</given-names></name> <name><surname>Kraemer</surname> <given-names>JD</given-names></name> <name><surname>Katz</surname> <given-names>R</given-names></name> <name><surname>Jha</surname> <given-names>AK</given-names></name> <name><surname>Kerry</surname> <given-names>VB</given-names></name> <name><surname>Sane</surname> <given-names>J</given-names></name> <etal/></person-group>. <article-title>Analysis of results from the Joint External Evaluation: examining its strength and assessing for trends among participating countries</article-title>. <source>J Glob Health.</source> (<year>2018</year>) <volume>8</volume>:<fpage>020416</fpage>. <pub-id pub-id-type="doi">10.7189/jogh.08.020416</pub-id><pub-id pub-id-type="pmid">30410738</pub-id></citation></ref>
<ref id="B37">
<label>37.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Oppenheim</surname> <given-names>B</given-names></name> <name><surname>Gallivan</surname> <given-names>M</given-names></name> <name><surname>Madhav</surname> <given-names>NK</given-names></name> <name><surname>Brown</surname> <given-names>N</given-names></name> <name><surname>Serhiyenko</surname> <given-names>V</given-names></name> <name><surname>Wolfe</surname> <given-names>ND</given-names></name> <etal/></person-group>. <article-title>Assessing global preparedness for the next pandemic: development and application of an Epidemic Preparedness Index</article-title>. <source>BMJ Global Health</source>. (<year>2019</year>) <volume>4</volume>:<fpage>e001157</fpage>. <pub-id pub-id-type="doi">10.1136/bmjgh-2018-001157</pub-id><pub-id pub-id-type="pmid">30775006</pub-id></citation></ref>
<ref id="B38">
<label>38.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Chen</surname> <given-names>YY</given-names></name> <name><surname>Feng</surname> <given-names>JH</given-names></name> <name><surname>Chen</surname> <given-names>A</given-names></name> <name><surname>Lee</surname> <given-names>JE</given-names></name> <name><surname>An</surname> <given-names>L</given-names></name></person-group>. <article-title>Risk perception of COVID-19: a comparative analysis of China and South Korea</article-title>. <source>Int J Disast Risk Res</source>. (<year>2021</year>) <volume>61</volume>:<fpage>102373</fpage>. <pub-id pub-id-type="doi">10.1016/j.ijdrr.2021.102373</pub-id><pub-id pub-id-type="pmid">34079690</pub-id></citation></ref>
<ref id="B39">
<label>39.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Dryhurst</surname> <given-names>S</given-names></name> <name><surname>Schneider</surname> <given-names>CR</given-names></name> <name><surname>Kerr</surname> <given-names>J</given-names></name> <name><surname>Freeman</surname> <given-names>ALJ</given-names></name> <name><surname>Recchia</surname> <given-names>G</given-names></name> <name><surname>van der Bles</surname> <given-names>AM</given-names></name> <etal/></person-group>. <article-title>Risk perceptions of COVID-19 around the world</article-title>. <source>J Risk Res.</source> (<year>2020</year>) <volume>23</volume>:<fpage>994</fpage>&#x02013;<lpage>1006</lpage>. <pub-id pub-id-type="doi">10.1080/13669877.2020.1758193</pub-id></citation>
</ref>
<ref id="B40">
<label>40.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Monge-Rodr&#x000ED;guez</surname> <given-names>FS</given-names></name> <name><surname>Jiang</surname> <given-names>H</given-names></name> <name><surname>Zhang</surname> <given-names>L</given-names></name> <name><surname>Alvarado-Yepez</surname> <given-names>A</given-names></name> <name><surname>Cardona-Rivero</surname> <given-names>A</given-names></name> <name><surname>Huaman-Chulluncuy</surname> <given-names>E</given-names></name> <etal/></person-group>. <article-title>Psychological factors affecting risk perception of COVID-19: evidence from Peru and China</article-title>. <source>Int J Environ Res Public Health</source>. (<year>2021</year>) <volume>18</volume>:<fpage>6513</fpage>. <pub-id pub-id-type="doi">10.3390/ijerph18126513</pub-id><pub-id pub-id-type="pmid">34204231</pub-id></citation></ref>
<ref id="B41">
<label>41.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bidzan</surname> <given-names>M</given-names></name> <name><surname>Bidzan-Bluma</surname> <given-names>I</given-names></name> <name><surname>Szulman-Wardal</surname> <given-names>A</given-names></name> <name><surname>Stueck</surname> <given-names>M</given-names></name> <name><surname>Bidzan</surname> <given-names>M</given-names></name></person-group>. <article-title>Does self-efficacy and emotional control protect hospital staff from COVID-19 anxiety and PTSD symptoms? Psychological functioning of hospital staff after the announcement of COVID-19 coronavirus pandemic</article-title>. <source>Front Psychol</source>. (<year>2020</year>) <volume>11</volume>:<fpage>552583</fpage>. <pub-id pub-id-type="doi">10.3389/fpsyg.2020.552583</pub-id><pub-id pub-id-type="pmid">33424673</pub-id></citation></ref>
<ref id="B42">
<label>42.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hu</surname> <given-names>N</given-names></name> <name><surname>Li</surname> <given-names>Y</given-names></name> <name><surname>He</surname> <given-names>S-S</given-names></name> <name><surname>Wang</surname> <given-names>L-L</given-names></name> <name><surname>Wei</surname> <given-names>Y-Y</given-names></name> <name><surname>Yin</surname> <given-names>L</given-names></name> <etal/></person-group>. <article-title>Impact of the family environment on the emotional state of medical staff during the COVID-19 outbreak: the mediating effect of self-efficacy</article-title>. <source>Front Psychol</source>. (<year>2020</year>) <volume>11</volume>:<fpage>576515</fpage>. <pub-id pub-id-type="doi">10.3389/fpsyg.2020.576515</pub-id><pub-id pub-id-type="pmid">33162916</pub-id></citation></ref>
<ref id="B43">
<label>43.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Tse</surname> <given-names>DM-S</given-names></name> <name><surname>Li</surname> <given-names>Z</given-names></name> <name><surname>Lu</surname> <given-names>Y</given-names></name> <name><surname>Li</surname> <given-names>Y</given-names></name> <name><surname>Liu</surname> <given-names>Y</given-names></name> <name><surname>Wong</surname> <given-names>WCW</given-names></name></person-group>. <article-title>Fighting against COVID-19: preparedness and implications on clinical practice in primary care in Shenzhen, China</article-title>. <source>BMC Family Practice</source>. (<year>2020</year>) <volume>21</volume>:<fpage>1</fpage>&#x02013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1186/s12875-020-01343-2</pub-id><pub-id pub-id-type="pmid">33339508</pub-id></citation></ref>
<ref id="B44">
<label>44.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Maunder</surname> <given-names>RG</given-names></name> <name><surname>Lancee</surname> <given-names>WJ</given-names></name> <name><surname>Mae</surname> <given-names>R</given-names></name> <name><surname>Vincent</surname> <given-names>L</given-names></name> <name><surname>Peladeau</surname> <given-names>N</given-names></name> <name><surname>Beduz</surname> <given-names>MA</given-names></name> <etal/></person-group>. <article-title>Computer-assisted resilience training to prepare healthcare workers for pandemic influenza: a randomized trial of the optimal dose of training</article-title>. <source>BMC Health Serv Res</source>. (<year>2010</year>) <volume>10</volume>:<fpage>1</fpage>&#x02013;<lpage>10</lpage>. <pub-id pub-id-type="doi">10.1186/1472-6963-10-72</pub-id><pub-id pub-id-type="pmid">20307302</pub-id></citation></ref>
<ref id="B45">
<label>45.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Xiao</surname> <given-names>H</given-names></name> <name><surname>Zhang</surname> <given-names>Y</given-names></name> <name><surname>Kong</surname> <given-names>D</given-names></name> <name><surname>Li</surname> <given-names>S</given-names></name> <name><surname>Yang</surname> <given-names>N</given-names></name></person-group>. <article-title>The effects of social support on sleep quality of medical staff treating patients with coronavirus disease 2019 (COVID-19) in January and February 2020 in China</article-title>. <source>Med Sci Monitor</source>. (<year>2020</year>) <volume>26</volume>: <fpage>e923549</fpage>&#x02013;<lpage>1</lpage>. <pub-id pub-id-type="doi">10.12659/MSM.923549</pub-id><pub-id pub-id-type="pmid">32132521</pub-id></citation></ref>
<ref id="B46">
<label>46.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kichloo</surname> <given-names>A</given-names></name> <name><surname>Albosta</surname> <given-names>M</given-names></name> <name><surname>Dettloff</surname> <given-names>K</given-names></name> <name><surname>Wani</surname> <given-names>F</given-names></name> <name><surname>El-Amir</surname> <given-names>Z</given-names></name> <name><surname>Singh</surname> <given-names>J</given-names></name> <etal/></person-group>. <article-title>Telemedicine, the current COVID-19 pandemic and the future: a narrative review and perspectives moving forward in the USA</article-title>. <source>Family Med Commun Health</source>. (<year>2020</year>) <volume>46</volume>:<fpage>1</fpage>&#x02013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1136/fmch-2020-000530</pub-id><pub-id pub-id-type="pmid">32816942</pub-id></citation></ref>
<ref id="B47">
<label>47.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Rawaf</surname> <given-names>S</given-names></name> <name><surname>Allen</surname> <given-names>LN</given-names></name> <name><surname>Stigler</surname> <given-names>FL</given-names></name> <name><surname>Kringos</surname> <given-names>D</given-names></name> <name><surname>Quezada Yamamoto</surname> <given-names>H</given-names></name> <name><surname>van Weel</surname> <given-names>C</given-names></name> <etal/></person-group>. <article-title>Lessons on the COVID-19 pandemic, for and by primary care professionals worldwide</article-title>. <source>Eur J Gen Pract.</source> (<year>2020</year>) <volume>26</volume>:<fpage>129</fpage>&#x02013;<lpage>33</lpage>. <pub-id pub-id-type="doi">10.1080/13814788.2020.1820479</pub-id><pub-id pub-id-type="pmid">32985278</pub-id></citation></ref>
<ref id="B48">
<label>48.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hasell</surname> <given-names>J</given-names></name> <name><surname>Mathieu</surname> <given-names>E</given-names></name> <name><surname>Beltekian</surname> <given-names>D</given-names></name> <name><surname>Macdonald</surname> <given-names>B</given-names></name> <name><surname>Giattino</surname> <given-names>C</given-names></name> <name><surname>Ortiz-Ospina</surname> <given-names>E</given-names></name> <etal/></person-group>. <article-title>A cross-country database of COVID-19 testing</article-title>. <source>Sci Data</source>. (<year>2020</year>) <volume>7</volume>:<fpage>1</fpage>&#x02013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1038/s41597-020-00688-8</pub-id><pub-id pub-id-type="pmid">33033256</pub-id></citation></ref>
<ref id="B49">
<label>49.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Iacobucci</surname> <given-names>G</given-names></name></person-group>. <article-title>Covid-19: Doctors still at &#x0201C;considerable risk&#x0201D; from lack of PPE, BMA warns</article-title>. <source>BMJ.</source> (<year>2020</year>) <volume>368</volume>:<fpage>m1316</fpage>. <pub-id pub-id-type="doi">10.1136/bmj.m1316</pub-id><pub-id pub-id-type="pmid">32234713</pub-id></citation></ref>
<ref id="B50">
<label>50.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Newman</surname> <given-names>M</given-names></name></person-group>. <article-title>Covid-19: doctors&#x00027; leaders warn that staff could quit and may die over lack of protective equipment</article-title>. <source>BMJ.</source> (<year>2020</year>) <volume>26</volume>:<fpage>368</fpage>. <pub-id pub-id-type="doi">10.1136/bmj.m1257</pub-id><pub-id pub-id-type="pmid">32217522</pub-id></citation></ref>
<ref id="B51">
<label>51.</label>
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Van Poel</surname> <given-names>E</given-names></name> <name><surname>Vanden Bussche</surname> <given-names>P</given-names></name> <name><surname>Klemenc-Ketis</surname> <given-names>Z</given-names></name> <name><surname>Willems</surname> <given-names>S</given-names></name></person-group>. <article-title>How did general practices organize care during the COVID-19 pandemic: the protocol of the cross-sectional PRICOV-19 study in 38 countries</article-title>. <source>BMC Primary Care</source>. (<year>2022</year>) <volume>23</volume>:<fpage>1</fpage>&#x02013;<lpage>11</lpage>. <pub-id pub-id-type="doi">10.1186/s12875-021-01587-6</pub-id><pub-id pub-id-type="pmid">35172744</pub-id></citation></ref>
</ref-list>
</back>
</article>