<?xml version="1.0" encoding="UTF-8" standalone="no"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.3 20070202//EN" "journalpublishing.dtd">
<article xml:lang="EN" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="editorial">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Psychol.</journal-id>
<journal-title>Frontiers in Psychology</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Psychol.</abbrev-journal-title>
<issn pub-type="epub">1664-1078</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpsyg.2025.1637687</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Psychology</subject>
<subj-group>
<subject>Editorial</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Editorial: A collection of systematic reviews or meta-analyses on the non-pharmaceutical interventions for social, health and psychological well-being</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name><surname>Bai</surname> <given-names>Zhenggang</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/644555/overview"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Fu</surname> <given-names>Fang</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/414781/overview"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name><surname>Chi</surname> <given-names>Iris</given-names></name>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
<xref ref-type="aff" rid="aff4"><sup>4</sup></xref>
<xref ref-type="corresp" rid="c001"><sup>&#x0002A;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/1040571/overview"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/>
</contrib>
</contrib-group>
<aff id="aff1"><sup>1</sup><institution>Institute of Clinical Research, Evidence-based Medicine Center of Traditional Chinese Medicine, Nanjing University of Chinese Medicine</institution>, <addr-line>Nanjing</addr-line>, <country>China</country></aff>
<aff id="aff2"><sup>2</sup><institution>Department of Social Work, Fudan University</institution>, <addr-line>Shanghai</addr-line>, <country>China</country></aff>
<aff id="aff3"><sup>3</sup><institution>School of Social Work, University of Southern California</institution>, <addr-line>Los Angeles, CA</addr-line>, <country>United States</country></aff>
<aff id="aff4"><sup>4</sup><institution>Sao Center on Aging, University of Hong Kong, Hong Kong</institution>, <addr-line>Hong Kong SAR</addr-line>, <country>China</country></aff>
<author-notes>
<fn fn-type="edited-by"><p>Edited and reviewed by: Gianluca Castelnuovo, Catholic University of the Sacred Heart, Italy</p></fn>
<corresp id="c001">&#x0002A;Correspondence: Iris Chi <email>ichi&#x00040;usc.edu</email></corresp>
</author-notes>
<pub-date pub-type="epub">
<day>15</day>
<month>09</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="collection">
<year>2025</year>
</pub-date>
<volume>16</volume>
<elocation-id>1637687</elocation-id>
<history>
<date date-type="received">
<day>29</day>
<month>05</month>
<year>2025</year>
</date>
<date date-type="accepted">
<day>26</day>
<month>08</month>
<year>2025</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x000A9; 2025 Bai, Fu and Chi.</copyright-statement>
<copyright-year>2025</copyright-year>
<copyright-holder>Bai, Fu and Chi</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<related-article id="RA1" related-article-type="commentary-article" xlink:href="https://www.frontiersin.org/research-topics/54744/a-collection-of-systematic-reviews-or-meta-analyses-on-the-non-pharmaceutical-interventions-for-social-health-and-psychological-well-being" ext-link-type="uri">Editorial on the Research Topic <article-title>A collection of systematic reviews or meta-analyses on the non-pharmaceutical interventions for social, health and psychological well-being</article-title></related-article>
<kwd-group>
<kwd>non-pharmaceutical intervention</kwd>
<kwd>evidence based</kwd>
<kwd>wellbeing</kwd>
<kwd>systematic review</kwd>
<kwd>meta-analysis</kwd>
</kwd-group>
<counts>
<fig-count count="0"/>
<table-count count="0"/>
<equation-count count="0"/>
<ref-count count="6"/>
<page-count count="3"/>
<word-count count="1461"/>
</counts>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Psychology for Clinical Settings</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="s1">
<title>Introduction</title>
<p>Evidence-based practice (EBP) seeks to integrate the strongest empirical findings with practitioners&#x00027; professional judgment while fully respecting the characteristics and preferences of service recipients. Since Sackett et al. first articulated the concept approximately three decades ago (<xref ref-type="bibr" rid="B5">Sackett et al., 1996</xref>), it has become the guiding principle in medicine, social work, education, and mental healthcare (<xref ref-type="bibr" rid="B1">Bai et al., 2022</xref>). Although randomized controlled trials (RCTs) yield the most rigorous primary data, systematic reviews and meta-analyses prepared in line with PRISMA standards (<xref ref-type="bibr" rid="B4">Moher et al., 2009</xref>) and appraised using the GRADE methodology (<xref ref-type="bibr" rid="B2">Guyatt et al., 2011</xref>; <xref ref-type="bibr" rid="B3">Higgins et al., 2022</xref>) translate scattered results into clear, practice-ready guidance.</p>
<p>The present cross-journal Research Topic (2025), organized with support from the Campbell China Network, assembles five high-quality syntheses that address prevention, treatment, and health promotion across the life course. A concise overview of the contributions is included.</p>
<sec>
<title>School-based prevention for adolescents</title>
<p><italic>Effectiveness of preventive interventions on teens&#x00027; depression and suicidal tendency</italic> screens 13 RCTs published since 2011 (<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fpsyg.2025.1356816">Ghazal et al.</ext-link>). The review reports modest yet clinically relevant reductions in depressive symptoms when cognitive-behavioral or psycho-educational programs are delivered by mental-health specialists. Owing to considerable heterogeneity in program content, dosage, and follow-up duration, the authors call for future studies to adopt standardized outcome indicators and transparent implementation reports.</p>
</sec>
<sec>
<title>Evolution of dialectical behavior therapy (DBT) research</title>
<p><italic>Bibliometric analysis of global research on dialectical behavior therapy from 1987 to 2024</italic> examines 2,723 publications and reveals that DBT scholarship has expanded beyond borderline personality disorder into the adolescent, forensic, and digital arenas, yet remains concentrated in the Global North (<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fpsyg.2025.1450497">Shi et al.</ext-link>). The mapping underscores the need for broader international collaboration and culturally responsive adaptations to DBT.</p>
</sec>
<sec>
<title>Culturally informed mind-body intervention</title>
<p>In <italic>research on the intervention effect of Five-Element Music Combined with Eight-Section Brocade on depression among medical students</italic>, 160 students were randomized to music therapy, Qigong exercise, a combined protocol, or usual care (<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fpsyg.2024.1439713">Yao et al.</ext-link>). Both single-component interventions improved depression, anxiety, and sleep, but the combined protocol produced the largest gains, suggesting a synergistic effect that merits wider promotion in campus health services.</p>
</sec>
<sec>
<title>Digital technology for youth mental health</title>
<p><italic>Promoting mental health in children and adolescents through digital technology</italic> synthesizes 59 studies (10 pooled in meta-analysis) and reports a moderate overall benefit (Hedges g = 0.43) for mobile apps, virtual reality platforms, serious games, and online counseling (<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fpsyg.2024.1356554">Chen et al.</ext-link>). Effect sizes, however, fluctuate with platform type, engagement strategy, and symptom focus, highlighting the importance of detailed process evaluations to elucidate mechanisms of change.</p>
</sec>
<sec>
<title>Exercise and chronic inflammation in healthy populations</title>
<p><italic>Long-term exercise training and inflammatory biomarkers in healthy subjects</italic> pools 38 RCTs (<italic>n</italic> = 2,557) and confirms that programs lasting at least 12 weeks, delivered at moderate intensity, significantly reduce IL-6, C-reactive protein, and TNF-&#x003B1; (<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fpsyg.2023.1253329">Wang et al.</ext-link>). These findings support exercise as a feasible primary prevention strategy, which may reduce long-term disease risk even in otherwise healthy individuals.</p>
</sec>
</sec>
<sec id="s2">
<title>Emerging themes and implications</title>
<p>Early intervention across multiple domains. The collected studies converge on the value of timely, non-pharmaceutical action, whether via classroom skill-building, digital coaching, culturally grounded mind-body practice, or structured physical activity, in shaping trajectories of wellbeing. This perspective aligns with WHO guidance on adolescent mental-health promotion (<xref ref-type="bibr" rid="B6">World Health Organization, 2020</xref>).</p>
<p>Cultural adaptation and contextual relevance. The Five-Element Music plus Eight-Section Brocade trial demonstrates that interventions rooted in indigenous traditions can satisfy strict methodological requirements. At the same time, the DBT bibliometric review reminds us that global applicability cannot be assumed without local evidence.</p>
<p>Methodological progress and remaining challenges. Most reviews comply with PRISMA and register their protocols prospectively, yet gaps persist in the long-term follow-up and reporting of implementation fidelity. Addressing these issues will sharpen future meta-analytic conclusions and enhance knowledge translation.</p>
<p>Interdisciplinary collaboration. The evidence base spans public health, psychology, kinesiology, music therapy, and information technology. Such breadth mirrors the multifaceted nature of real-world problems and calls for integrative intervention packages to be evaluated through collaborative research designs.</p>
</sec>
<sec id="s3">
<title>Recommendations for future work</title>
<p>Multi-component trials should examine additive or synergistic effects, as demonstrated in the Five-Element Music plus Eight-Section Brocade study.</p>
<p>Equity-oriented research capacity must be strengthened, especially in low- and middle-income regions, to ensure that global evidence truly represents diverse populations.</p>
<p>Precision implementation science is needed to match interventions to individual and contextual characteristics, thereby realizing the full intent of EBP.</p>
<p>Mechanistic and longitudinal outcomes (e.g., biological markers and digital engagement metrics) should complement symptom measures to clarify how and for whom these interventions work.</p>
</sec>
<sec id="s4">
<title>Concluding remarks</title>
<p>This Research Topic underscores that non-pharmaceutical interventions, from school-based cognitive training to traditional mind-body practices, rest on a solid and growing empirical foundation. By conscientiously integrating these high-quality syntheses into routine practice, professionals can deliver person-centered, culturally sensitive, and scientifically informed services that foster social, health, and psychological wellbeing across populations.</p>
</sec>
</body>
<back>
<sec sec-type="author-contributions" id="s5">
<title>Author contributions</title>
<p>ZB: Writing &#x02013; original draft. FF: Writing &#x02013; review &#x00026; editing. IC: Writing &#x02013; review &#x00026; editing.</p>
</sec>
<sec sec-type="COI-statement" id="conf1">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="ai-statement" id="s6">
<title>Generative AI statement</title>
<p>The author(s) declare that no Gen AI was used in the creation of this manuscript.</p>
<p>Any alternative text (alt text) provided alongside figures in this article has been generated by Frontiers with the support of artificial intelligence and reasonable efforts have been made to ensure accuracy, including review by the authors wherever possible. If you identify any issues, please contact us.</p>
</sec>
<sec sec-type="disclaimer" id="s7">
<title>Publisher&#x00027;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<ref-list>
<title>References</title>
<ref id="B1">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bai</surname> <given-names>Z. G.</given-names></name> <name><surname>Bai</surname> <given-names>R. H.</given-names></name> <name><surname>Duan</surname> <given-names>J. Y.</given-names></name> <name><surname>Liu</surname> <given-names>M. N.</given-names></name> <name><surname>Jin</surname> <given-names>W. J.</given-names></name> <name><surname>Chi</surname> <given-names>I.</given-names></name></person-group> (<year>2022</year>). <article-title>Evidence-based social science in China paper 2: the history and development of evidence-based social work in China</article-title>. <source>J. Clin. Epidemiol.</source> <volume>141</volume>, <fpage>151</fpage>&#x02013;<lpage>156</lpage>. <pub-id pub-id-type="doi">10.1016/j.jclinepi.2021.09.030</pub-id><pub-id pub-id-type="pmid">34670111</pub-id></citation></ref>
<ref id="B2">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Guyatt</surname> <given-names>G. H.</given-names></name> <name><surname>Oxman</surname> <given-names>A. D.</given-names></name> <name><surname>Vist</surname> <given-names>G. E.</given-names></name> <name><surname>Kunz</surname> <given-names>R.</given-names></name> <name><surname>Falck-Ytter</surname> <given-names>Y.</given-names></name> <name><surname>Alonso-Coello</surname> <given-names>P.</given-names></name> <etal/></person-group>. (<year>2011</year>). <article-title>GRADE guidelines: 1. Introduction&#x02014;GRADE evidence profiles and summary of findings tables</article-title>. <source>J. Clin. Epidemiol.</source> <volume>64</volume>, <fpage>383</fpage>&#x02013;<lpage>394</lpage>. <pub-id pub-id-type="doi">10.1016/j.jclinepi.2010.04.026</pub-id><pub-id pub-id-type="pmid">21195583</pub-id></citation></ref>
<ref id="B3">
<citation citation-type="web"><person-group person-group-type="author"><name><surname>Higgins</surname> <given-names>J. P. T.</given-names></name> <name><surname>Thomas</surname> <given-names>J.</given-names></name> <name><surname>Chandler</surname> <given-names>J.</given-names></name> <name><surname>Cumpston</surname> <given-names>M.</given-names></name> <name><surname>Li</surname> <given-names>T.</given-names></name> <name><surname>Page</surname> <given-names>M. J.</given-names></name> <etal/></person-group>. (<year>2022</year>). Cochrane handbook for systematic reviews of interventions (Version 6.3). Cochrane. Available online at: <ext-link ext-link-type="uri" xlink:href="https://training.cochrane.org/handbook">https://training.cochrane.org/handbook</ext-link> (Accessed June 7, 2025).</citation>
</ref>
<ref id="B4">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Moher</surname> <given-names>D.</given-names></name> <name><surname>Liberati</surname> <given-names>A.</given-names></name> <name><surname>Tetzlaff</surname> <given-names>J.</given-names></name> <name><surname>Altman</surname> <given-names>D. G.</given-names></name> <collab>PRISMA Group</collab></person-group>. (<year>2009</year>). <article-title>Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement</article-title>. <source>PLoS Med.</source> <volume>6</volume>:<fpage>e1000097</fpage>. <pub-id pub-id-type="doi">10.1371/journal.pmed.1000097</pub-id><pub-id pub-id-type="pmid">19621072</pub-id></citation></ref>
<ref id="B5">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sackett</surname> <given-names>D. L.</given-names></name> <name><surname>Rosenberg</surname> <given-names>W. M. C.</given-names></name> <name><surname>Gray</surname> <given-names>J. A. M.</given-names></name> <name><surname>Haynes</surname> <given-names>R. B.</given-names></name> <name><surname>Richardson</surname> <given-names>W. S.</given-names></name></person-group> (<year>1996</year>). <article-title>Evidence-based medicine: what it is and what it isn&#x00027;t</article-title>. <source>BMJ</source> <volume>312</volume>, <fpage>71</fpage>&#x02013;<lpage>72</lpage>. <pub-id pub-id-type="doi">10.1136/bmj.312.7023.71</pub-id><pub-id pub-id-type="pmid">8555924</pub-id></citation></ref>
<ref id="B6">
<citation citation-type="web"><person-group person-group-type="author"><collab>World Health Organization</collab></person-group> (<year>2020</year>). <source>Guidelines on mental health promotive and preventive interventions for adolescents: Helping adolescents thrive toolkit</source>. World Health Organization. Available online at: <ext-link ext-link-type="uri" xlink:href="https://www.who.int/publications/i/item/9789240016514">https://www.who.int/publications/i/item/9789240016514</ext-link> (Accessed June 8, 2025).</citation>
</ref>
</ref-list>
</back>
</article>