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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Psychol.</journal-id>
<journal-title>Frontiers in Psychology</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Psychol.</abbrev-journal-title>
<issn pub-type="epub">1664-1078</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpsyg.2023.1255604</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Psychology</subject>
<subj-group>
<subject>Original Research</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Predicting online information seeking on Douyin, Baidu, and other Chinese search engines among gynecologic oncology patients: a cross-sectional study</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Xiong</surname>
<given-names>Wenli</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<role content-type="https://credit.niso.org/contributor-roles/data-curation/"/>
<role content-type="https://credit.niso.org/contributor-roles/investigation/"/>
<role content-type="https://credit.niso.org/contributor-roles/software/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Li</surname>
<given-names>Xiaohong</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Han</surname>
<given-names>Yun</given-names>
</name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<role content-type="https://credit.niso.org/contributor-roles/data-curation/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>He</surname>
<given-names>Lijuan</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="corresp" rid="c001"><sup>&#x002A;</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/2371890/overview"/>
<role content-type="https://credit.niso.org/contributor-roles/conceptualization/"/>
<role content-type="https://credit.niso.org/contributor-roles/data-curation/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/>
</contrib>
</contrib-group>
<aff id="aff1"><sup>1</sup><institution>Health Management Center, Affiliated Hospital of Southwest Medical University</institution>, <addr-line>Luzhou, Sichuan</addr-line>, <country>China</country></aff>
<aff id="aff2"><sup>2</sup><institution>Department of Urology, Yibin Fifth People&#x2019;s Hospital</institution>, <addr-line>Yibin, Sichuan</addr-line>, <country>China</country></aff>
<author-notes>
<fn fn-type="edited-by" id="fn0001">
<p>Edited by: Renata Colombo Bonadio, University of S&#x00E3;o Paulo, Brazil</p>
</fn>
<fn fn-type="edited-by" id="fn0002">
<p>Reviewed by: Iuliana Raluca Gheorghe, Carol Davila University of Medicine and Pharmacy, Romania; Federica Perelli, Santa Maria Annunziata Hospital, Italy</p>
</fn>
<corresp id="c001">&#x002A;Correspondence: Lijuan He, <email>15181993200@163.com</email></corresp>
</author-notes>
<pub-date pub-type="epub">
<day>23</day>
<month>11</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="collection">
<year>2023</year>
</pub-date>
<volume>14</volume>
<elocation-id>1255604</elocation-id>
<history>
<date date-type="received">
<day>13</day>
<month>07</month>
<year>2023</year>
</date>
<date date-type="accepted">
<day>06</day>
<month>11</month>
<year>2023</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2023 Xiong, Li, Han and He.</copyright-statement>
<copyright-year>2023</copyright-year>
<copyright-holder>Xiong, Li, Han and He.</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<sec id="sec1">
<title>Objective</title>
<p>The rise of online platforms like Douyin, Baidu, and other Chinese search engines has changed how gynecologic oncology patients seek information about their diagnosis or condition. This study aimed to investigate the factors associated with information seeking among these patients and to evaluate their predictive performance.</p>
</sec>
<sec id="sec2">
<title>Methods</title>
<p>A cross-sectional study was conducted among 199 gynecologic oncology patients at a single hospital in China. The patients&#x2019; demographic characteristics and scores on the State&#x2013;Trait Anxiety Inventory (STAI-S and STAI-T) and the Hospital Anxiety and Depression Scale (HADS-A and HADS-D) were compared between those who sought information online and those who did not. Logistic regression analyses and receiver operating characteristic (ROC) curve analyses were performed.</p>
</sec>
<sec id="sec3">
<title>Results</title>
<p>The patients&#x2019; age, marital status, STAI-S scores, and HADS-A scores were significantly associated with online information seeking. The combined model that included these factors showed good predictive performance with an area under the ROC curve of 0.841.</p>
</sec>
<sec id="sec4">
<title>Conclusion</title>
<p>The combination of demographic and psychological factors can be used to predict the likelihood of gynecologic oncology patients seeking information online. These findings can help healthcare providers understand their patients&#x2019; information-seeking behaviors and tailor their communication strategies accordingly.</p>
</sec>
</abstract>
<kwd-group>
<kwd>gynecologic oncology</kwd>
<kwd>information seeking</kwd>
<kwd>online platforms</kwd>
<kwd>Douyin</kwd>
<kwd>Baidu</kwd>
<kwd>anxiety</kwd>
<kwd>depression</kwd>
<kwd>prediction model</kwd>
</kwd-group>
<counts>
<fig-count count="1"/>
<table-count count="3"/>
<equation-count count="0"/>
<ref-count count="29"/>
<page-count count="6"/>
<word-count count="4568"/>
</counts>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Health Psychology</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="sec5">
<title>Introduction</title>
<p>In the digital age, the internet plays an increasingly central role in the way patients seek and obtain health-related information. Online platforms have grown to become a vital source of health information for patients, enabling them to learn about their conditions, understand treatment options, and engage more effectively in their healthcare (<xref ref-type="bibr" rid="ref20">Moorhead et al., 2013</xref>; <xref ref-type="bibr" rid="ref7">Duggan et al., 2014</xref>; <xref ref-type="bibr" rid="ref1">Amante et al., 2015</xref>). In China, the trend of online health information seeking is pronounced, with individuals frequently turning to the internet for health science popularization, health behaviors, traditional Chinese medicine, and medical inquiries (<xref ref-type="bibr" rid="ref27">Xiong et al., 2021</xref>). The outbreak of Severe Acute Respiratory Syndrome (SARS) in 2003 marked a significant rise in online health information-seeking behaviors, leading to the burgeoning of health websites in the country (<xref ref-type="bibr" rid="ref6">Cao et al., 2016</xref>).</p>
<p>With over 989 million active users, Douyin, known internationally as TikTok, has emerged as one of China&#x2019;s most popular social media platforms (<xref ref-type="bibr" rid="ref11">Iqbal, 2021</xref>). In addition, Baidu, China&#x2019;s leading search engine, attracts hundreds of millions of users each month (<xref ref-type="bibr" rid="ref17">McDougall, 2014</xref>). These platforms and other Chinese search engines have significantly altered the landscape of patient education and health information seeking. A particular study among college students in Guangdong Province revealed that individuals sought health information primarily for self-care, general health, disease prevention, self-medication, family treatment, and drug information, among others, utilizing platforms like <ext-link xlink:href="http://Baike.baidu.com" ext-link-type="uri">Baike.baidu.com</ext-link>, <ext-link xlink:href="http://Zhihu.com" ext-link-type="uri">Zhihu.com</ext-link>, and <ext-link xlink:href="http://Zhidao.baidu.com" ext-link-type="uri">Zhidao.baidu.com</ext-link> (<xref ref-type="bibr" rid="ref28">Zhang et al., 2021</xref>).</p>
<p>A key demographic group navigating this digital landscape is patients diagnosed with gynecologic cancers, a group of cancers that affect women&#x2019;s reproductive organs. These include cervical cancer, ovarian cancer, uterine cancer, vaginal cancer, and vulvar cancer, which together represent a significant health burden for women worldwide (<xref ref-type="bibr" rid="ref4">Bray et al., 2018</xref>). As the complexity of gynecologic oncology increases with advancements in diagnosis and treatment modalities, so too does the necessity for patients to seek comprehensible and reliable information about their condition (<xref ref-type="bibr" rid="ref19">Miller et al., 2022</xref>). This narrative aligns with the overarching themes elucidated in a comprehensive review on gynecologic oncology, emphasizing the paramountcy of accurate diagnostic methodologies and prognostic stratifications in enhancing patients&#x2019; survival and quality of life amidst the battle against gynecological malignancies (<xref ref-type="bibr" rid="ref21">Perelli et al., 2023</xref>).</p>
<p>The process of seeking health information online is influenced by a myriad of factors, including demographic characteristics such as age, gender, education level, and income, as well as psychological factors like anxiety and depression (<xref ref-type="bibr" rid="ref9">Gray et al., 2005</xref>; <xref ref-type="bibr" rid="ref26">Wang et al., 2013</xref>; <xref ref-type="bibr" rid="ref25">Tennant et al., 2015</xref>). The State&#x2013;Trait Anxiety Inventory (STAI) and the Hospital Anxiety and Depression Scale (HADS) are among the validated instruments used to measure these psychological states (<xref ref-type="bibr" rid="ref24">Spielberger et al., 1971</xref>; <xref ref-type="bibr" rid="ref29">Zigmond and Snaith, 1983</xref>). However, the specific factors associated with online information seeking among gynecologic oncology patients, particularly on platforms like Douyin and Baidu, remain poorly understood.</p>
<p>Given these online platforms&#x2019; growing prevalence and potential impact on patient health outcomes, a comprehensive understanding of the characteristics and psychological states influencing a patient&#x2019;s propensity to seek online health information is critical. Studies have demonstrated that patients who actively seek health information tend to be more involved in decision-making about their health, exhibit better self-management of their conditions, and generally have better health outcomes (<xref ref-type="bibr" rid="ref18">McMullan, 2006</xref>; <xref ref-type="bibr" rid="ref13">Lambert and Loiselle, 2007</xref>). However, it is also worth noting that the information seeking process can result in increased anxiety and distress, especially if the information obtained is conflicting, misunderstood, or if the patient stumbles upon worst-case scenarios (<xref ref-type="bibr" rid="ref5">Broom, 2005</xref>; <xref ref-type="bibr" rid="ref16">Leykin et al., 2012</xref>). Thus, it is crucial to identify which patients are more likely to seek online health information and understand their psychological states to provide appropriate guidance and support.</p>
<p>Further, in the era of personalized medicine, it is crucial to use predictive models that allow healthcare professionals to identify patients who are more likely to seek online information about their diagnosis or condition. These predictive models can aid in tailoring patient education and communication strategies, thus enhancing patient care (<xref ref-type="bibr" rid="ref22">Schapira et al., 2017</xref>). Although numerous studies have focused on the relationship between internet use and health outcomes, few have attempted to develop predictive models for online information seeking behavior (<xref ref-type="bibr" rid="ref15">Leung and Lee, 2005</xref>; <xref ref-type="bibr" rid="ref14">Lee et al., 2014</xref>). The vast landscape of online health information in China and the particular preferences of individuals in seeking such information underscore the importance of our case study.</p>
<p>Our study seeks to fill the gap in understanding the online health information-seeking behaviors among gynecologic oncology patients in China, leveraging demographic and psychological data. By doing so, we aim to build a predictive model that could help clinicians better understand their patients&#x2019; information-seeking behaviors, inform strategies for patient communication and education, and contribute to improved patient outcomes in the realm of gynecologic oncology.</p>
</sec>
<sec sec-type="methods" id="sec6">
<title>Methods</title>
<sec id="sec7">
<title>Study design and participants</title>
<p>This was a cross-sectional study conducted among gynecologic oncology patients at a single hospital in China utilizing a convenience sampling method. All patients visiting the Gynecologic Oncology department during the study period and meeting the inclusion criteria were invited to participate. The study included patients who were over 18&#x2009;years of age, had a confirmed diagnosis of gynecologic cancer, and had the ability to use online platforms such as Douyin, Baidu, and other Chinese search engines. Patients were excluded if they were unable to comprehend or complete the survey. The types of gynecological cancers considered in this study included Ovarian Cancer, Uterine Cancer, and Cervical Cancer. In total, 199 patients participated in the study, 91 of whom sought information about their diagnosis or condition online, and 108 of whom did not.</p>
</sec>
<sec id="sec8">
<title>Data collection</title>
<p>A structured questionnaire was administered through face-to-face interviews conducted by trained medical staff. Data was collected on patients&#x2019; demographic characteristics, including age, marital status, education level, and annual income. The patients&#x2019; psychological states were assessed using the State&#x2013;Trait Anxiety Inventory (STAI-S and STAI-T) and the Hospital Anxiety and Depression Scale (HADS-A and HADS-D). Participants were assured of the confidentiality of their responses, with data being anonymized before analysis and securely stored with restricted access.</p>
</sec>
<sec id="sec9">
<title>Translation, validation, and administration of questionnaires</title>
<p>The State&#x2013;Trait Anxiety Inventory (STAI) and the Hospital Anxiety and Depression Scale (HADS) were translated into Mandarin Chinese by bilingual experts, using a forward and backward translation method to ensure accuracy. A small sample of gynecologic oncology patients participated in cognitive interviews to assess the clarity and relevance of the translated questionnaires. Previous studies have validated the translated versions of STAI and HADS in Mandarin Chinese, showing satisfactory psychometric properties. Our preliminary analysis also confirmed good internal consistency with Cronbach&#x2019;s alpha values consistent with those reported in existing literature. Questionnaires were administered by trained research staff fluent in Mandarin Chinese, with assistance provided to participants as needed to clarify any uncertainties and ensure accurate responses.</p>
</sec>
<sec id="sec10">
<title>Statistical analysis</title>
<p>Descriptive statistics were used to summarize the characteristics of the patients. Chi-square tests and t-tests were conducted to compare the demographic and psychological characteristics between patients who sought information online and those who did not. Univariate and multivariate logistic regression analyses were used to identify the factors associated with online information seeking. The performance of the identified predictors was assessed using receiver operating characteristic (ROC) curve analysis, and the optimal cut-off values were determined based on the Youden index. All statistical analyses were conducted using R software, with a <italic>p</italic>-value of less than 0.05 considered statistically significant.</p>
</sec>
</sec>
<sec sec-type="results" id="sec11">
<title>Results</title>
<sec id="sec12">
<title>Characteristics of gynecologic oncology patients seeking information on Douyin, Baidu, and other Chinese search engines</title>
<p><xref ref-type="table" rid="tab1">Table 1</xref> provides an overview of the demographic and psychological characteristics of the gynecologic oncology patients in our study who used platforms such as Douyin, Baidu, and other Chinese search engines to seek information about their diagnosis or condition, compared to those who did not. The table shows the data for both groups, including the number of patients (91 who used the platforms and 108 who did not), average age, marital status, educational background, annual income, as well as scores on the STAI-S, STAI-T, HADS-A, and HADS-D psychological scales. From this table, we can see some statistically significant differences between the two groups. Patients who sought information on these platforms were younger on average (54.956&#x2009;&#x00B1;&#x2009;8.029&#x2009;years) compared to those who did not (62.593&#x2009;&#x00B1;&#x2009;6.6206&#x2009;years, <italic>p</italic>&#x2009;&#x003C;&#x2009;0.001). Marital status also varied significantly between the groups (<italic>p</italic>&#x2009;=&#x2009;0.045), with a larger proportion of unmarried patients in the group that did not use these platforms. Differences in education levels were striking, with a significantly larger percentage of patients with high school education or less in the group not using the platforms. Annual income also varied, with the group using the platforms having a larger percentage in the higher income brackets. Psychologically, patients who sought information had higher STAI-S and STAI-T scores, indicative of greater levels of state and trait anxiety, respectively. Their median HADS-A scores were also higher, suggesting more symptoms of anxiety, but there was no significant difference in the HADS-D scores, indicating depressive symptoms.</p>
<table-wrap position="float" id="tab1">
<label>Table 1</label>
<caption>
<p>Characteristics of gynecologic oncology patients seeking information on Douyin, Baidu, and other Chinese search engines.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Characteristics</th>
<th align="center" valign="top">Yes</th>
<th align="center" valign="top">No</th>
<th align="center" valign="top"><italic>p</italic> value</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top"><italic>n</italic></td>
<td align="center" valign="top">91</td>
<td align="center" valign="top">108</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Age, mean&#x2009;&#x00B1;&#x2009;sd</td>
<td align="center" valign="top">54.956&#x2009;&#x00B1;&#x2009;8.029</td>
<td align="center" valign="top">62.593&#x2009;&#x00B1;&#x2009;6.6206</td>
<td align="center" valign="top">&#x003C;0.001</td>
</tr>
<tr>
<td align="left" valign="top">marital_status, <italic>n</italic> (%)</td>
<td/>
<td/>
<td align="center" valign="top">0.045</td>
</tr>
<tr>
<td align="left" valign="top">Unmarried</td>
<td align="center" valign="top">31 (34%)</td>
<td align="center" valign="top">52 (48.1%)</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Married/partnered</td>
<td align="center" valign="top">60 (66%)</td>
<td align="center" valign="top">56 (51.9%)</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Education, <italic>n</italic> (%)</td>
<td/>
<td/>
<td align="center" valign="top">&#x003C;0.001</td>
</tr>
<tr>
<td align="left" valign="top">&#x003C;High school</td>
<td align="center" valign="top">2 (2.2%)</td>
<td align="center" valign="top">8 (7.4%)</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">High school</td>
<td align="center" valign="top">17 (18.7%)</td>
<td align="center" valign="top">30 (27.8%)</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Technical school/some college</td>
<td align="center" valign="top">18 (19.8%)</td>
<td align="center" valign="top">39 (36.1%)</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">College degree (3- or 4-year)</td>
<td align="center" valign="top">35 (38.5%)</td>
<td align="center" valign="top">20 (18.5%)</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Graduate/professional degree</td>
<td align="center" valign="top">19 (20.9%)</td>
<td align="center" valign="top">11 (10.2%)</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">annual_income, <italic>n</italic> (%)</td>
<td/>
<td/>
<td align="center" valign="top">0.010</td>
</tr>
<tr>
<td align="left" valign="top">&#x003C;25,000</td>
<td align="center" valign="top">11 (12.1%)</td>
<td align="center" valign="top">28 (25.9%)</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">25,000-49,000</td>
<td align="center" valign="top">17 (18.7%)</td>
<td align="center" valign="top">17 (15.7%)</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">50,000-99,000</td>
<td align="center" valign="top">31 (34.1%)</td>
<td align="center" valign="top">24 (22.2%)</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">&#x2265;100,000</td>
<td align="center" valign="top">29 (31.9%)</td>
<td align="center" valign="top">26 (24.1%)</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Not reported</td>
<td align="center" valign="top">3 (3.3%)</td>
<td align="center" valign="top">13 (12%)</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">stai_s, mean&#x2009;&#x00B1;&#x2009;sd</td>
<td align="center" valign="top">38.352&#x2009;&#x00B1;&#x2009;5.7684</td>
<td align="center" valign="top">34.759&#x2009;&#x00B1;&#x2009;5.9811</td>
<td align="center" valign="top">&#x003C; 0.001</td>
</tr>
<tr>
<td align="left" valign="top">stai_t, mean&#x2009;&#x00B1;&#x2009;sd</td>
<td align="center" valign="top">36.308&#x2009;&#x00B1;&#x2009;5.4154</td>
<td align="center" valign="top">34.731&#x2009;&#x00B1;&#x2009;5.4578</td>
<td align="center" valign="top">0.043</td>
</tr>
<tr>
<td align="left" valign="top">hads_a, median (IQR)</td>
<td align="center" valign="top">7 (6, 9)</td>
<td align="center" valign="top">6 (4.75, 8)</td>
<td align="center" valign="top">&#x003C; 0.001</td>
</tr>
<tr>
<td align="left" valign="top">hads_d, median (IQR)</td>
<td align="center" valign="top">4 (3, 6)</td>
<td align="center" valign="top">4 (2, 5.25)</td>
<td align="center" valign="top">0.139</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>The table categorizes patients based on their online information-seeking behavior (Yes or No). Age is shown as mean&#x2009;&#x00B1;&#x2009;standard deviation (sd). Marital status, education, and annual income are given as number (<italic>n</italic>) and percentage (%). State&#x2013;Trait Anxiety Inventory (STAI) scores are denoted as state anxiety (stai_s) and trait anxiety (stai_t), both shown as mean&#x2009;&#x00B1;&#x2009;sd. Hospital Anxiety and Depression Scale (HADS) scores are split into anxiety (hads_a) and depression (hads_d), and expressed as median with interquartile range (IQR). <italic>p</italic> values less than 0.05 indicate statistical significance.</p>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="sec13">
<title>Univariate and multivariate analysis of factors associated with information seeking on Douyin, Baidu, and other Chinese search engines among gynecologic oncology patients</title>
<p><xref ref-type="table" rid="tab2">Table 2</xref> elucidates the outcomes of both univariate and multivariate analyses probing the factors associated with gynecologic oncology patients seeking information regarding their diagnosis or condition on platforms like Douyin, Baidu, and other Chinese search engines. The table delineates odds ratios, confidence intervals, and <italic>p</italic>-values for each scrutinized factor, encompassing age, marital status, and scores on the STAI-S, STAI-T, HADS-A, and HADS-D psychological scales. In the univariate analysis, age exhibited a significant association with information-seeking behavior, presenting an odds ratio of 0.870 (95% CI: 0.827&#x2013;0.915, <italic>p</italic>&#x2009;&#x003C;&#x2009;0.001). This association was further accentuated in the multivariate analysis, with an odds ratio of 0.853 (95% CI: 0.807&#x2013;0.901, p&#x2009;&#x003C;&#x2009;0.001), indicating a decrease in the likelihood of seeking information online with advancing age. When examining marital status, the &#x2018;married/partnered&#x2019; category was juxtaposed against the &#x2018;unmarried&#x2019; category, serving as the reference group. Both univariate and multivariate analyses disclosed that being married or partnered was linked with higher odds of seeking information (OR&#x2009;=&#x2009;2.25, 95% CI: 1.25&#x2013;4.05, <italic>p</italic>&#x2009;=&#x2009;0.008 in univariate; OR&#x2009;=&#x2009;2.50, 95% CI: 1.40&#x2013;4.45, <italic>p</italic>&#x2009;=&#x2009;0.002 in multivariate). Additionally, scores on the STAI-S, STAI-T, and HADS-A scales were significantly associated with information seeking in both univariate and multivariate analyses, suggesting a relationship between certain psychological well-being facets and the propensity to seek information online. Conversely, HADS-D scores, indicative of depressive symptoms, demonstrated no significant association in the univariate analysis and hence, were excluded from the multivariate analysis.</p>
<table-wrap position="float" id="tab2">
<label>Table 2</label>
<caption>
<p>Univariate and multivariate analysis of factors associated with information seeking on Douyin, Baidu, and other Chinese search engines among gynecologic oncology patients.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top" rowspan="2">Characteristics</th>
<th align="center" valign="top" rowspan="2">Total (<italic>N</italic>)</th>
<th align="center" valign="top" colspan="2">Univariate analysis</th>
<th align="center" valign="top" colspan="2">Multivariate analysis</th>
</tr>
<tr>
<th align="center" valign="top">Odds Ratio (95% CI)</th>
<th align="center" valign="top"><italic>p</italic> value</th>
<th align="center" valign="top">Odds Ratio (95% CI)</th>
<th align="center" valign="top"><italic>p</italic> value</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="middle">Age</td>
<td align="center" valign="middle">199</td>
<td align="center" valign="middle">0.870 (0.827&#x2013;0.915)</td>
<td align="center" valign="middle"><bold>&#x003C;0.001</bold></td>
<td align="center" valign="middle">0.853 (0.807&#x2013;0.901)</td>
<td align="center" valign="middle"><bold>&#x003C;0.001</bold></td>
</tr>
<tr>
<td align="left" valign="middle">marital_status</td>
<td align="center" valign="middle">199</td>
<td/>
<td/>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="middle">Unmarried</td>
<td align="center" valign="middle">83</td>
<td align="center" valign="middle">Reference</td>
<td/>
<td align="center" valign="middle">Reference</td>
<td/>
</tr>
<tr>
<td align="left" valign="middle">Married/partnered</td>
<td align="center" valign="middle">116</td>
<td align="center" valign="middle">2.25 (1.25&#x2013;4.05)</td>
<td align="center" valign="middle"><bold>0.008</bold></td>
<td align="center" valign="middle">2.50 (1.40&#x2013;4.45)</td>
<td align="center" valign="middle"><bold>0.002</bold></td>
</tr>
<tr>
<td align="left" valign="middle">stai_s</td>
<td align="center" valign="middle">199</td>
<td align="center" valign="middle">1.102 (1.050&#x2013;1.157)</td>
<td align="center" valign="middle"><bold>&#x003C;0.001</bold></td>
<td align="center" valign="middle">1.095 (1.042&#x2013;1.151)</td>
<td align="center" valign="middle"><bold>&#x003C;0.001</bold></td>
</tr>
<tr>
<td align="left" valign="middle">stai_t</td>
<td align="center" valign="middle">199</td>
<td align="center" valign="middle">1.080 (1.020&#x2013;1.143)</td>
<td align="center" valign="middle"><bold>0.039</bold></td>
<td align="center" valign="middle">1.073 (1.013&#x2013;1.138)</td>
<td align="center" valign="middle">0.216</td>
</tr>
<tr>
<td align="left" valign="middle">hads_a</td>
<td align="center" valign="middle">199</td>
<td align="center" valign="middle">1.150 (1.080&#x2013;1.225)</td>
<td align="center" valign="middle"><bold>&#x003C;0.001</bold></td>
<td align="center" valign="middle">1.130 (1.060&#x2013;1.205)</td>
<td align="center" valign="middle"><bold>&#x003C;0.001</bold></td>
</tr>
<tr>
<td align="left" valign="middle">hads_d</td>
<td align="center" valign="middle">199</td>
<td align="center" valign="middle">1.000 (0.900&#x2013;1.100)</td>
<td align="center" valign="middle">0.139</td>
<td/>
<td/>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>The table presents a univariate and multivariate analysis of different characteristics and their association with online information-seeking behavior among the participants. The total number of participants (<italic>N</italic>) is 199. Odds Ratios (OR) with 95% Confidence Intervals (95% CI) and <italic>p</italic> values are provided for both univariate and multivariate analysis. The Reference category in marital_status represents the baseline group for comparison. <italic>p</italic> values less than 0.05 are considered statistically significant.</p>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="sec14">
<title>Performance of age, STAI-S, STAI-T, HADS-A, and the combined model in predicting information seeking on Douyin, Baidu, and other Chinese search engines among gynecologic oncology patients</title>
<p><xref ref-type="table" rid="tab3">Table 3</xref> compares the performance of age, STAI-S, STAI-T, and HADS-A scores, as well as a combined model, in predicting whether gynecologic oncology patients would seek information about their diagnosis or condition on platforms like Douyin, Baidu, and other Chinese search engines. The parameters evaluated include area under the receiver operating characteristic curve (AUC), 95% confidence interval (CI), cut-off values for each predictor, and specificity and sensitivity at these cut-off values. For each of the predictors, age performed the best with an AUC of 0.776 (95% CI: 0.709&#x2013;0.843), a cut-off value of 57.5, specificity of 64.835%, and sensitivity of 81.481%. The STAI-S and HADS-A scores showed moderate performance, with AUCs of 0.673 (95% CI: 0.598&#x2013;0.747) and 0.645 (95% CI: 0.569&#x2013;0.721), respectively. The STAI-T scores had the lowest AUC at 0.591 (95% CI: 0.511&#x2013;0.670). The combined model, which takes all these factors into account, outperformed any single predictor, with an AUC of 0.841 (95% CI: 0.787&#x2013;0.895), specificity of 75.824%, and sensitivity of 77.778%. These results highlight the potential of using a combination of demographic and psychological factors to predict information-seeking behavior in this patient population. A ROC curve was plotted for the model, see <xref ref-type="fig" rid="fig1">Figure 1</xref>.</p>
<table-wrap position="float" id="tab3">
<label>Table 3</label>
<caption>
<p>Performance of age, STAI-S, STAI-T, HADS-A, and the combined model in predicting information seeking on Douyin, Baidu, and other Chinese search engines among gynecologic oncology patients.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Parameters</th>
<th align="center" valign="top">AUC</th>
<th align="center" valign="top">95% CI</th>
<th align="center" valign="top">Cut-off value</th>
<th align="center" valign="top">Specificity (%)</th>
<th align="center" valign="top">Sensitivity (%)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Age</td>
<td align="center" valign="top">0.776</td>
<td align="center" valign="top">0.709&#x2013;0.843</td>
<td align="center" valign="top">57.5</td>
<td align="center" valign="top">0.64835</td>
<td align="center" valign="top">0.81481</td>
</tr>
<tr>
<td align="left" valign="top">stai_s</td>
<td align="center" valign="top">0.673</td>
<td align="center" valign="top">0.598&#x2013;0.747</td>
<td align="center" valign="top">36.5</td>
<td align="center" valign="top">0.61538</td>
<td align="center" valign="top">0.65741</td>
</tr>
<tr>
<td align="left" valign="top">stai_t</td>
<td align="center" valign="top">0.591</td>
<td align="center" valign="top">0.511&#x2013;0.670</td>
<td align="center" valign="top">37.5</td>
<td align="center" valign="top">0.40659</td>
<td align="center" valign="top">0.75926</td>
</tr>
<tr>
<td align="left" valign="top">hads_a</td>
<td align="center" valign="top">0.645</td>
<td align="center" valign="top">0.569&#x2013;0.721</td>
<td align="center" valign="top">5.5</td>
<td align="center" valign="top">0.8022</td>
<td align="center" valign="top">0.41667</td>
</tr>
<tr>
<td align="left" valign="top">Model</td>
<td align="center" valign="top">0.841</td>
<td align="center" valign="top">0.787&#x2013;0.895</td>
<td align="center" valign="top">0.14178</td>
<td align="center" valign="top">0.75824</td>
<td align="center" valign="top">0.77778</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>This table presents the performance of different parameters and a combined model in predicting the information-seeking behavior on Douyin, Baidu, and other Chinese search engines among the participants. The parameters include age, state anxiety (STAI-S), trait anxiety (STAI-T), and anxiety from the Hospital Anxiety and Depression Scale (HADS-A). The Area Under the Curve (AUC) with 95% Confidence Intervals (95% CI) are provided to show the performance of each parameter and the combined model in predicting information-seeking behavior. The cut-off values, specificity, and sensitivity percentages are also provided for each parameter and the combined model to further evaluate their predictive accuracy.</p>
</table-wrap-foot>
</table-wrap>
<fig position="float" id="fig1">
<label>Figure 1</label>
<caption>
<p>A ROC curve for the model.</p>
</caption>
<graphic xlink:href="fpsyg-14-1255604-g001.tif"/>
</fig>
</sec>
</sec>
<sec sec-type="discussion" id="sec15">
<title>Discussion</title>
<p>This research illuminates the online health information-seeking behaviors among gynecologic oncology patients in China, a demographic navigating the digital landscape primarily through popular platforms like Douyin and Baidu. The comprehensive analysis conducted in this study underscores the critical influence of demographic and psychological factors on these behaviors.</p>
<p>China, with its vast population and rapidly evolving digital infrastructure, presents a unique context for exploring online health information-seeking behaviors. The penetration of internet services and digital platforms has significantly increased over the years, enabling a large segment of the population to access online resources for health-related information. This backdrop provides a fertile ground for understanding the interplay of demographic and psychological factors in influencing online health information-seeking tendencies among gynecologic oncology patients.</p>
<p>The association of older age with reduced online information seeking, as observed in our study, aligns with previous studies (<xref ref-type="bibr" rid="ref23">Smith, 2014</xref>), hinting at a digital divide based on age. However, ongoing digital literacy initiatives and the proliferation of internet-enabled devices may potentially bridge this divide over time, a trajectory worthy of investigation in future research (<xref ref-type="bibr" rid="ref2">Anderson and Perrin, 2017</xref>).</p>
<p>Furthermore, the differing online information-seeking behaviors between married or partnered individuals and their unmarried counterparts open avenues for exploring the role of social support in health information-seeking processes (<xref ref-type="bibr" rid="ref12">LaCoursiere et al., 2005</xref>). The intricacies of social dynamics and their impact on online health information-seeking behaviors could be a focal point for future research.</p>
<p>From a psychological lens, our findings accentuate the role of state anxiety in online health information-seeking behavior. Although previous research has highlighted the roles of both anxiety and depression in health information seeking (<xref ref-type="bibr" rid="ref8">Eastin and Guinsler, 2006</xref>; <xref ref-type="bibr" rid="ref3">Bessi&#x00E8;re et al., 2010</xref>), our study uniquely reveals that only state anxiety significantly associates with this behavior within the Chinese context, where mental health symptoms may manifest or be reported differently (<xref ref-type="bibr" rid="ref10">Hsiao et al., 2006</xref>).</p>
<p>The predictive model crafted in this study serves as a robust tool in forecasting online health information-seeking behaviors among gynecologic oncology patients, holding substantial implications for healthcare providers. By understanding a patient&#x2019;s demographic and psychological profile, healthcare providers can tailor communication strategies to better meet the informational needs of their patients.</p>
<p>Nonetheless, the model&#x2019;s predictive prowess was not flawless, hinting at other possibly influential factors not encapsulated in our study. Future explorations could delve into additional predictors like health literacy, perceived health status, and trust in online health information to further refine the understanding of online health information-seeking behaviors among gynecologic oncology patients in China.</p>
</sec>
<sec sec-type="conclusions" id="sec16">
<title>Conclusion</title>
<p>In summation, our investigation unveils the complex tapestry of factors shaping online health information-seeking behaviors among gynecologic oncology patients in China. The insights gleaned from this study lay a solid groundwork for devising targeted patient education and communication strategies, ultimately fostering enhanced patient engagement and healthcare outcomes in the burgeoning digital age. Through a nuanced understanding of the demographic and psychological factors at play, healthcare providers can better navigate the digital health information landscape alongside their patients, driving forward the agenda of informed patient-centric care in the digital epoch.</p>
</sec>
<sec sec-type="data-availability" id="sec17">
<title>Data availability statement</title>
<p>The original contributions presented in the study are included in the article/<xref ref-type="supplementary-material" rid="SM1">Supplementary material</xref>, further inquiries can be directed to the corresponding author.</p>
</sec>
<sec sec-type="ethics-statement" id="sec18">
<title>Ethics statement</title>
<p>This investigation was undertaken with the sanction of the Ethics Committee of The Affiliated Hospital of Southwest Medical University (Ethics code number: KY2023200). All methods were conducted in compliance with relevant guidelines, regulations, and the Declaration of Helsinki. All participants provided written informed consent before participating in the study.</p>
</sec>
<sec sec-type="author-contributions" id="sec19">
<title>Author contributions</title>
<p>WX: Data curation, Investigation, Software, Writing &#x2013; original draft. XL: Writing - review &#x0026; editing. YH: Data curation, Writing &#x2013; original draft. LH: Conceptualization, Data curation, Writing &#x2013; original draft.</p>
</sec>
</body>
<back>
<sec sec-type="funding-information" id="sec20">
<title>Funding</title>
<p>The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.</p>
</sec>
<ack>
<p>We would like to express our sincere gratitude to all individuals who contributed to the completion of this study.</p>
</ack>
<sec sec-type="COI-statement" id="sec21">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="sec100" sec-type="disclaimer">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec sec-type="supplementary-material" id="sec22">
<title>Supplementary material</title>
<p>The Supplementary material for this article can be found online at: <ext-link xlink:href="https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1255604/full#supplementary-material" ext-link-type="uri">https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1255604/full#supplementary-material</ext-link></p>
<supplementary-material xlink:href="Data_Sheet_1.docx" id="SM1" mimetype="application/vnd.openxmlformats-officedocument.wordprocessingml.document" xmlns:xlink="http://www.w3.org/1999/xlink"/>
<supplementary-material xlink:href="Table_1.docx" id="SM2" mimetype="application/vnd.openxmlformats-officedocument.wordprocessingml.document" xmlns:xlink="http://www.w3.org/1999/xlink"/>
</sec>
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