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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Psychol.</journal-id>
<journal-title>Frontiers in Psychology</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Psychol.</abbrev-journal-title>
<issn pub-type="epub">1664-1078</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpsyg.2023.1101886</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Psychology</subject>
<subj-group>
<subject>Original Research</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Assessment of validity and comparison of two Spanish versions of the Geriatric Depression Scale</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Bugallo-Carrera</surname> <given-names>Cesar</given-names></name><xref rid="aff1" ref-type="aff"><sup>1</sup></xref>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Dosil-D&#x00ED;az</surname> <given-names>Carlos</given-names></name><xref rid="aff1" ref-type="aff"><sup>1</sup></xref><xref rid="c001" ref-type="corresp"><sup>&#x002A;</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/1106194/overview"/>
</contrib>
<contrib contrib-type="author"><name><surname>Pereiro</surname> <given-names>Arturo X.</given-names></name><xref rid="aff1" ref-type="aff"><sup>1</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/453168/overview"/>
</contrib>
<contrib contrib-type="author"><name><surname>Anido-Rif&#x00F3;n</surname> <given-names>Lu&#x00ED;s</given-names></name><xref rid="aff2" ref-type="aff"><sup>2</sup></xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pacheco-Lorenzo</surname> <given-names>Mois&#x00E9;s</given-names></name><xref rid="aff2" ref-type="aff"><sup>2</sup></xref>
</contrib>
<contrib contrib-type="author"><name><surname>Fern&#x00E1;ndez-Iglesias</surname> <given-names>Manuel J.</given-names></name><xref rid="aff2" ref-type="aff"><sup>2</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/153984/overview"/>
</contrib>
<contrib contrib-type="author"><name><surname>Gandoy-Crego</surname> <given-names>Manuel</given-names></name><xref rid="aff3" ref-type="aff"><sup>3</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/668184/overview"/>
</contrib>
</contrib-group>
<aff id="aff1"><sup>1</sup><institution>Department of Developmental Psychology, University of Santiago de Compostela</institution>, <addr-line>Santiago de Compostela</addr-line>, <country>Spain</country></aff>
<aff id="aff2"><sup>2</sup><institution>AtlanTTic Research Center, University of Vigo</institution>, <addr-line>Vigo</addr-line>, <country>Spain</country></aff>
<aff id="aff3"><sup>3</sup><institution>Department of Psychiatry, Radiology, Public Health, Nursing and Medicine, University of Santiago de Compostela</institution>, <addr-line>Santiago de Compostela</addr-line>, <country>Spain</country></aff>
<author-notes>
<fn id="fn0001" fn-type="edited-by">
<p>Edited by: Fengyu Zhang, Global Clinical and Translational Research Institute, United States</p>
</fn>
<fn id="fn0002" fn-type="edited-by">
<p>Reviewed by: Beatriz Bonete Lopez, Miguel Hern&#x00E1;ndez University of Elche, Spain; Miguel Clemente, University of A Coru&#x00F1;a, Spain</p>
</fn>
<corresp id="c001">&#x002A;Correspondence: Carlos Dosil-D&#x00ED;az, <email>carlos.dosil@usc.es</email></corresp>
</author-notes>
<pub-date pub-type="epub">
<day>17</day>
<month>05</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="collection">
<year>2023</year>
</pub-date>
<volume>14</volume>
<elocation-id>1101886</elocation-id>
<history>
<date date-type="received">
<day>18</day>
<month>11</month>
<year>2022</year>
</date>
<date date-type="accepted">
<day>21</day>
<month>04</month>
<year>2023</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2023 Bugallo-Carrera, Dosil-D&#x00ED;az, Pereiro, Anido-Rif&#x00F3;n, Pacheco-Lorenzo, Fern&#x00E1;ndez-Iglesias and Gandoy-Crego.</copyright-statement>
<copyright-year>2023</copyright-year>
<copyright-holder>Bugallo-Carrera, Dosil-D&#x00ED;az, Pereiro, Anido-Rif&#x00F3;n, Pacheco-Lorenzo, Fern&#x00E1;ndez-Iglesias and Gandoy-Crego</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<sec>
<title>Introduction</title>
<p>The Geriatric Depression Scale is an instrument used to identify depression in people of an older age. The original English version of this scale has been translated into Spanish (GDS-<italic>VE</italic>); two shorter versions of 5- (GDS-5) and 15-items (GDS-15) have been developed.</p>
</sec>
<sec>
<title>Aim of the study</title>
<p>To assess the validity and compare the 5- and 15-item Spanish versions of the GDS among the Spanish population.</p>
</sec>
<sec>
<title>Materials and methods</title>
<p>573 Galicia residents aged &#x003E;50 years participated in this study. The following instruments were applied: the 19-item Control, Autonomy, Self-Realization and Pleasure scale, the Subjective Memory Complaints Questionnaire, the Mini-Mental State Examination test, the GDS-5, and the GDS-15.</p>
</sec>
<sec>
<title>Results</title>
<p>We found differences in total score between GDS-5 and GDS-15 regarding the variable sex. Internal reliability for GDS-5 and GDS-15 was 0.495 and 0.715, respectively. Sensitivity and specificity for GDS-5 &#x2013; with a cut-off value of 1 &#x2013; was 0.517 and 0.650, respectively; for GDS-15 &#x2013; with a cut-off value of 3 points &#x2013; sensitivity was 0.755 and specificity 0.668. GDS-5 has a ROC curve of 0.617 and GDS-15 of 0.764.</p>
</sec>
<sec>
<title>Conclusion</title>
<p>GDS-15, and to a greater extent GDS-5, should be revised or even reformulated to improve their diagnostic usefulness by choosing higher discriminative ability items or even include new items with greater sensitivity that consider currently prevailing psychosocial factors.</p>
</sec>
</abstract>
<kwd-group>
<kwd>GDS</kwd>
<kwd>depression</kwd>
<kwd>older adults</kwd>
<kwd>validation</kwd>
<kwd>Spain</kwd>
</kwd-group>
<counts>
<fig-count count="0"/>
<table-count count="6"/>
<equation-count count="0"/>
<ref-count count="32"/>
<page-count count="6"/>
<word-count count="4755"/>
</counts>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Psychology of Aging</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec id="sec6" sec-type="intro">
<title>Introduction</title>
<p>To date, there are over 1,000 million people aged &#x2265;60&#x2009;years worldwide, with an estimated of 1,400 million by 2030 (<xref ref-type="bibr" rid="ref34">WHO, 2022</xref>). This increase of people of an older age &#x2013; associated to longer life expectancy &#x2013; implies physical and psychological challenges, changes often considered part of the aging process (<xref ref-type="bibr" rid="ref5">Blazer and Hybels, 2005</xref>). Mental disorders are expected to increase significantly, depression included (<xref ref-type="bibr" rid="ref11">Flood and Buckwalter, 2009</xref>). A large number of studies from various countries report on the prevalence of depression in people of an older age, although mostly, their data are distinct: from 7.6% in Malaysia to 81.1% in India (<xref ref-type="bibr" rid="ref35">Zenebe et al., 2021</xref>). This large variability results from the differences between the studied territories regarding the perception/stigma of mental health disorders, the health system, or the instruments used for their detection (<xref ref-type="bibr" rid="ref10">Ferrari et al., 2013</xref>; <xref ref-type="bibr" rid="ref17">Krishnamoorthy et al., 2020</xref>; <xref ref-type="bibr" rid="ref26">Moreno-Agostino et al., 2021</xref>), often leading to a wrong diagnosis (<xref ref-type="bibr" rid="ref31">Stek et al., 2004</xref>). In older adults, depression is a major public health problem that increases emotional distress and worsens comorbid conditions; consequently, there is a rise in healthcare costs (<xref ref-type="bibr" rid="ref20">Luppa et al., 2008</xref>), besides a significant increase in suicide and other cause mortality (<xref ref-type="bibr" rid="ref2">Aziz and Steffens, 2013</xref>; <xref ref-type="bibr" rid="ref21">Malhi and Mann, 2018</xref>; <xref ref-type="bibr" rid="ref01">Jiang et al., 2020</xref>).</p>
<p>However, in old age not everything is negative, since it is known that there are a series of differential characteristics of the emotional experience of older people that help explain the phenomenon of the well-being paradox in old age, according to which, Despite the increase associated with old age in the frequency of negative life events such as illnesses or emotional losses, older people continue to maintain similar or higher levels of subjective well-being. These characteristics can be summarized as less negative emotional experience, greater selectivity of emotional information, especially if it is rewarding, and greater control of emotions compared to younger people, presenting greater emotional stability and selecting more situations. In which they get involved, in order to optimize their emotional well-being (<xref ref-type="bibr" rid="ref7">Carstensen, 1993</xref>; <xref ref-type="bibr" rid="ref22">M&#x00E1;rquez-Gonz&#x00E1;lez et al., 2004</xref>).</p>
<p>Validated instruments are key to identify people with depression &#x2013; or who are at risk &#x2013; and act appropriately. Many instruments have been developed to identify depression in older adults, most validated at different times and with diverse populations (<xref ref-type="bibr" rid="ref12">Gokcekuyu et al., 2022</xref>). Thus, the development of these instruments are influenced by psychosocial factors strongly associated to the period and social context of their validation. This reinforces the interest of having reliable and valid tools to detect depression in people of an older age considering the existing time- and space-related psychosocial risks predominant at the assessment (<xref ref-type="bibr" rid="ref1">Are&#x00E1;n and Reynolds, 2005</xref>).</p>
<p>In 1983, the 30-item Geriatric Depression Scale (GDS-30) was developed (<xref ref-type="bibr" rid="ref6">Brink et al., 1982</xref>); later, a reduced 15-ited version was created (GDS-15) (<xref ref-type="bibr" rid="ref30">Sheikh and Yesavage, 1986</xref>). It was proved that these 15- or 30-item tests were difficult to complete for people of an older age with some type of disease and/or limitation due to visual of hearing impairments (<xref ref-type="bibr" rid="ref12">Gokcekuyu et al., 2022</xref>). Similarly, the quality and length of the exam may be affected in patients with conditions such as chronic pain or dementia. Thus, shorter tests that maintain adequate levels of reliability and validity were needed. Thus, in 1997, Hoyl and collaborators developed the 5-item Geriatric Depression Scale (GDS-5). In Spain, there are several Spanish versions of the GDS validated in community populations, e.g., GDS-<italic>VE</italic>30 (Spanish 30-item Geriatric Depression Scale) (<xref ref-type="bibr" rid="ref15">Izal et al., 2007</xref>), GDS-15 (Spanish Geriatric 15-item Depression Scale) (<xref ref-type="bibr" rid="ref8">de Dios del Valle et al., 2001</xref>; <xref ref-type="bibr" rid="ref23">Mart&#x00ED;nez de la Iglesia et al., 2002</xref>; <xref ref-type="bibr" rid="ref15">Izal et al., 2007</xref>; <xref ref-type="bibr" rid="ref28">Ortega Orcos et al., 2007</xref>), or the GDS-5 (Spanish 5-item Geriatric Depression Scale) (<xref ref-type="bibr" rid="ref8">de Dios del Valle et al., 2001</xref>; <xref ref-type="bibr" rid="ref15">Izal et al., 2007</xref>; <xref ref-type="bibr" rid="ref28">Ortega Orcos et al., 2007</xref>). Moreover, there are validated versions of the GDS-15 and GDS-5 for Spanish populations with cognitive deterioration (<xref ref-type="bibr" rid="ref19">Lucas-Carrasco, 2012</xref>; <xref rid="tab1" ref-type="table">Table 1</xref>).</p>
<table-wrap position="float" id="tab1">
<label>Table 1</label>
<caption>
<p>Five- and 15-item versions of the Geriatric Depression Scale and response options.</p>
</caption>
<table frame="hsides" rules="groups">
<tbody>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item>
<p>Are you satisfied with your life?</p>
</list-item>
</list>
</td>
<td>Yes</td>
<td>No</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item>
<p>Have you dropped many of your activities?</p>
</list-item>
</list>
</td>
<td>Yes</td>
<td>No</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item>
<p>Do you feel that your life is empty?</p>
</list-item>
</list>
</td>
<td align="center" valign="top">
<bold>Yes</bold>
</td>
<td align="center" valign="top">No</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item>
<p>Do you often get bored?</p>
</list-item>
</list>
</td>
<td align="center" valign="top">
<bold>Yes</bold>
</td>
<td align="center" valign="top">No</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item>
<p>Are you in good spirits most of the time?</p>
</list-item>
</list>
</td>
<td align="center" valign="top">Yes</td>
<td align="center" valign="top">
<bold>No</bold>
</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item>
<p>Are you afraid that something is going to happen to you?</p>
</list-item>
</list>
</td>
<td align="center" valign="top">
<bold>Yes</bold>
</td>
<td align="center" valign="top">No</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item>
<p>Do you feel happy most of the time?</p>
</list-item>
</list>
</td>
<td align="center" valign="top">Yes</td>
<td align="center" valign="top">
<bold>No</bold>
</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item>
<p>Do you often feel abandoned?</p>
</list-item>
</list>
</td>
<td align="center" valign="top">
<bold>Yes</bold>
</td>
<td align="center" valign="top">No</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item>
<p>Do you prefer to stay home rather than going out?</p>
</list-item>
</list>
</td>
<td align="center" valign="top">
<bold>Yes</bold>
</td>
<td align="center" valign="top">No</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item> <p>Do you feel you have more problems with memory than most people?</p></list-item>
</list>
</td>
<td align="center" valign="top">
<bold>Yes</bold>
</td>
<td align="center" valign="top">No</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item> <p>Do you think it is wonderful to be alive?</p></list-item>
</list>
</td>
<td align="center" valign="top">Yes</td>
<td align="center" valign="top">
<bold>No</bold>
</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item> <p>Is it hard for you to get started with new projects?</p></list-item>
</list>
</td>
<td align="center" valign="top">
<bold>Yes</bold>
</td>
<td align="center" valign="top">No</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item> <p>Do you feel full of energy?</p></list-item>
</list>
</td>
<td align="center" valign="top">Yes</td>
<td align="center" valign="top">
<bold>No</bold>
</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item> <p>Do you feel your situation is hopeless?</p></list-item>
</list>
</td>
<td align="center" valign="top">
<bold>Yes</bold>
</td>
<td align="center" valign="top">No</td>
</tr>
<tr>
<td align="left" valign="top">
<list list-type="order">
<list-item> <p>Do you feel most people are better off than you are?</p></list-item>
</list>
</td>
<td align="center" valign="top">
<bold>Yes</bold>
</td>
<td align="center" valign="top">No</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>Questions in bold correspond to the 5-item version of the scale. Responses indicating depression are in bold. Each of these answers counts one point.</p>
<p>Own elaboration.</p>
</table-wrap-foot>
</table-wrap>
<p>The purpose of this study was to validate and compare the GDS-5 and GDS-15 scales for the Spanish population and assess their psychometric properties.</p>
</sec>
<sec id="sec7" sec-type="methods">
<title>Methods</title>
<p>573 people aged &#x2265;50&#x2009;years were included in this study (<italic>M</italic>&#x2009;=&#x2009;70.09; SD&#x2009;=&#x2009;9.52). All were residents of Galicia (Northwest Spain) and were recruited through socio-cultural, professional, and civic associations. Participants were selected by convenience sampling to obtain a sample equally distributed based on age group, level of education, and sex. Inclusion criteria: aged &#x2265;50&#x2009;years and without psychiatric diseases or incapacitating sensory or motor deficit. Exclusion criteria: absence of cognitive impairment and illiteracy (participates had to at least know how to read and write). Signed informed consent was obtained from all participants.</p>
<p>Evaluations were performed by psychologists in the homes of the participates and socio-cultural centers. The instruments were applied in the following order, counterbalancing the GDS-5 and GDS-15 scales (<xref ref-type="bibr" rid="ref24">Mart&#x00ED;nez et al., 1993</xref>): a sociodemographic questionnaire (<xref ref-type="bibr" rid="ref29">Pereiro et al., 2017</xref>), the Spanish version of the Mini-Mental State Examination (MMSE, <xref ref-type="bibr" rid="ref18">Lobo et al., 1979</xref>), the GDS-5 scale (<xref ref-type="bibr" rid="ref24">Mart&#x00ED;nez et al., 1993</xref>), the Spanish version of the 19-item Control, Autonomy, Self-realization, Pleasure scale (CASP-19, <xref ref-type="bibr" rid="ref27">Netuveli et al., 2006</xref>), the Spanish version of the Subjective Memory Complaint Questionnaire (SMCQ, <xref ref-type="bibr" rid="ref4">Benedet et al., 1996</xref>), and the GDS-15 scales (<xref ref-type="bibr" rid="ref24">Mart&#x00ED;nez et al., 1993</xref>).</p>
<sec id="sec8">
<title>Data analysis</title>
<p>The same analyses of data were simultaneously done for both GDS-5 and GDS-15 versions.</p>
<p>Descriptive statistics were obtained from each sociodemographic variables included in the study. Student&#x2019;s <italic>t</italic>-test for independent samples was applied to determine the difference of total scale score for the variable sex. The relationships between total score for both scales and the variables age and education were assessed using Pearson&#x2019;s bivariate correlation. To determine which variables significantly and independently contributed on the overall scoring in both scales, different multiple linear regression analysis were done (using the stepwise procedure), including sex, age, years of schooling, and diagnosis of depression as predictive or independent variables. Using this type of analysis, we examined the effect of each independent variable on the total score for GDS-5 and GDS-15.</p>
<p>We used the Kuder&#x2013;Richardson Formula 20 (KR-20) to assess the internal reliability of the instruments. To validate the constructor, we examined the convergent validity, assessing the correlation between the GDS-5 / GDS-15 scales and the CASP-19 scale, which measures quality of life; similarly, we examined the discriminant validity by correlating the outcomes of the GDS-5/GDS-15 scales with total Subjective Memory Complaints Questionnaire (SMCQ) scores. In both cases, we calculated Spearman&#x2019;s rank correlation coefficient.</p>
<p>For the criterion or practice validity, we calculated the sensitivity, specificity, and cut-off values for both scales using the Younden index. The informed clinical diagnosis in the sociodemographic questionnaire was used as the gold standard. We analyzed the discriminative capacity of both study scales to differentiate between healthy and depressed subjects using the area under the Receiver Operating Characteristic (ROC) curve.</p>
<p>In order to know the distribution of the items that make up the GDS-15 and GDS-5 scales, the descriptive statistics of each one were obtained: the mean, the standard deviation, the skewness and the kurtosis.</p>
<p>To determine the dimensionality of the questionnaires, a factorial analysis of both was performed. For this, the Kaiser-Meyer-Olkin (KMO) statistic and Bartlett&#x2019;s sphericity test were used. With a KMO &#x003E;0.5 and a significant Bartlett&#x2019;s test, it would prove the existence of an underlying factor structure. The principal component extraction method was used, with Varimax rotation. The criterion of significant factor loadings was used those greater than &#x2265;0.40.</p>
<p>The ceiling and floor effects of the total scores of both scales were analyzed according to the percentage of participants with the lowest (floor) and highest (ceiling) total scores on the scales. Ceiling and floor effects are considered to be present if more than 15% of respondents achieve the highest or lowest possible total score (<xref ref-type="bibr" rid="ref32">Terwee et al., 2007</xref>). Data were analyzed using SPSS<sup>&#x00AE;</sup> Statistics 21 for Windows (IBM<sup>&#x00AE;</sup>, Armonk, NY).</p>
</sec>
</sec>
<sec id="sec9" sec-type="results">
<title>Results</title>
<p><xref rid="tab2" ref-type="table">Table 2</xref> shows the descriptive statistics of the sociodemographic variables included in this study. Student&#x2019;s <italic>t</italic>-test showed differences in total scores for the variable sex for GDS-5 (<italic>t</italic>&#x2009;=&#x2009;&#x2212;2.399; gl: 567; <italic>p</italic>&#x2009;&#x003C;&#x2009;0.05) and GDS-15 (<italic>t</italic>&#x2009;=&#x2009;&#x2212;4.767; gl: 567; <italic>p</italic>&#x2009;&#x003C;&#x2009;0.05). Significant correlations were found between total GDS-5 and GDS-15 scores and the variables age and years of schooling (<xref rid="tab3" ref-type="table">Table 3</xref>). Specifically, a significant positive correlation was seen for both study scales for age and a significant negative correlation for years of schooling.</p>
<table-wrap position="float" id="tab2">
<label>Table 2</label>
<caption>
<p>Descriptive statistics for the sociodemographic variables.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Variables</th>
<th align="center" valign="top">
<italic>N</italic>
</th>
<th align="center" valign="top">%</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Sex (female)</td>
<td align="center" valign="top">356</td>
<td align="center" valign="top">62.6</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Age</td>
</tr>
<tr>
<td align="left" valign="top">50&#x2013;59&#x2009;years</td>
<td align="center" valign="top">76</td>
<td align="center" valign="top">13.4</td>
</tr>
<tr>
<td align="left" valign="top">60&#x2013;69&#x2009;years</td>
<td align="center" valign="top">197</td>
<td align="center" valign="top">34.6</td>
</tr>
<tr>
<td align="left" valign="top">70&#x2013;79&#x2009;years</td>
<td align="center" valign="top">179</td>
<td align="center" valign="top">31.5</td>
</tr>
<tr>
<td align="left" valign="top">+ 80&#x2009;years</td>
<td align="center" valign="top">117</td>
<td align="center" valign="top">20.6</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Education (years)</td>
</tr>
<tr>
<td align="left" valign="top">0&#x2013;4&#x2009;years</td>
<td align="center" valign="top">74</td>
<td align="center" valign="top">13.0</td>
</tr>
<tr>
<td align="left" valign="top">5&#x2013;8&#x2009;years</td>
<td align="center" valign="top">257</td>
<td align="center" valign="top">45.2</td>
</tr>
<tr>
<td align="left" valign="top">9&#x2013;13&#x2009;years</td>
<td align="center" valign="top">137</td>
<td align="center" valign="top">24.1</td>
</tr>
<tr>
<td align="left" valign="top">+ 13&#x2009;years</td>
<td align="center" valign="top">101</td>
<td align="center" valign="top">17.8</td>
</tr>
<tr>
<td align="left" valign="top">Diagnosis of depression</td>
<td align="center" valign="top">58</td>
<td align="center" valign="top">10.2</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>Own elaboration.</p>
</table-wrap-foot>
</table-wrap>
<table-wrap position="float" id="tab3">
<label>Table 3</label>
<caption>
<p>Correlations between total GDS-VE5 and GDS-VE15 scores and the variables age and years of schooling.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th/>
<th/>
<th align="center" valign="top">GDS-15</th>
<th align="center" valign="top">GDS-5</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="middle" rowspan="3">Age</td>
<td align="left" valign="middle">Pearson&#x2019;s correlation</td>
<td align="center" valign="middle">0.157&#x002A;&#x002A;</td>
<td align="center" valign="middle">0.155&#x002A;&#x002A;</td>
</tr>
<tr>
<td align="left" valign="middle">Sig. (bilateral)</td>
<td align="center" valign="middle">0</td>
<td align="center" valign="middle">0</td>
</tr>
<tr>
<td align="left" valign="middle">N</td>
<td align="center" valign="middle">569</td>
<td align="center" valign="middle">569</td>
</tr>
<tr>
<td align="left" valign="middle" rowspan="3">Education</td>
<td align="left" valign="middle">Pearson&#x2019;s correlation</td>
<td align="center" valign="middle">&#x2212;0.184&#x002A;&#x002A;</td>
<td align="center" valign="middle">&#x2212;0.198&#x002A;&#x002A;</td>
</tr>
<tr>
<td align="left" valign="middle">Sig. (bilateral)</td>
<td align="center" valign="middle">0</td>
<td align="center" valign="middle">0.064</td>
</tr>
<tr>
<td align="left" valign="middle">N</td>
<td align="center" valign="middle">569</td>
<td align="center" valign="middle">569</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>GDS-VE, Geriatric Depression Scale (Spanish version).</p>
<p>&#x002A;&#x002A;<italic>p</italic>&#x2009;&#x003C;&#x2009;0.001.</p>
<p>Own elaboration.</p>
</table-wrap-foot>
</table-wrap>
<p>We carried out regression analyses to assess the individual effects of independent variables on GDS-5 and GDS-15 total scores (<xref rid="tab4" ref-type="table">Table 4</xref>). The independent variables years of schooling, being diagnosed with depression, and age are predictors for total GDS-5 score, while the independent variables sex, years of schooling, and being diagnosed with depression are predictors for total GDS-15 score.</p>
<table-wrap position="float" id="tab4">
<label>Table 4</label>
<caption>
<p>Significance of linear regression analyses of independent variables on total GDS-VE5 and GDS-VE15 scores.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Factors</th>
<th align="center" valign="top">
<italic>B</italic>
</th>
<th align="center" valign="top">Beta</th>
<th align="center" valign="top">
<italic>T</italic>
</th>
<th align="center" valign="top">Sig.</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="middle" colspan="5">Regression model on GDS-15 score</td>
</tr>
<tr>
<td align="left" valign="middle">Sex</td>
<td align="center" valign="middle">0.752</td>
<td align="center" valign="middle">0.147</td>
<td align="center" valign="middle">3.565</td>
<td align="center" valign="middle">0</td>
</tr>
<tr>
<td align="left" valign="middle">Years of schooling</td>
<td align="center" valign="middle">&#x2212;0.083</td>
<td align="center" valign="middle">&#x2212;0.118</td>
<td align="center" valign="middle">&#x2212;2.653</td>
<td align="center" valign="middle">0.008</td>
</tr>
<tr>
<td align="left" valign="middle">Diagnosis of depression</td>
<td align="center" valign="middle">&#x2212;1.305</td>
<td align="center" valign="middle">&#x2212;0.159</td>
<td align="center" valign="middle">&#x2212;3.911</td>
<td align="center" valign="middle">0</td>
</tr>
<tr>
<td align="left" valign="middle">Age</td>
<td align="center" valign="middle">0.028</td>
<td align="center" valign="middle">0.109</td>
<td align="center" valign="middle">2.468</td>
<td align="center" valign="middle">0.014</td>
</tr>
<tr>
<td align="left" valign="middle" colspan="5">Regression model on GDS-5 score</td>
</tr>
<tr>
<td align="left" valign="middle">Years of schooling</td>
<td align="center" valign="middle">&#x2212;0.051</td>
<td align="center" valign="middle">&#x2212;0.16</td>
<td align="center" valign="middle">&#x2212;3.576</td>
<td align="center" valign="middle">0</td>
</tr>
<tr>
<td align="left" valign="middle">Diagnosis of depression</td>
<td align="center" valign="middle">&#x2212;0.501</td>
<td align="center" valign="middle">&#x2212;0.135</td>
<td align="center" valign="middle">&#x2212;3.309</td>
<td align="center" valign="middle">0.001</td>
</tr>
<tr>
<td align="left" valign="middle">Age</td>
<td align="center" valign="middle">0.011</td>
<td align="center" valign="middle">0.093</td>
<td align="center" valign="middle">2.068</td>
<td align="center" valign="middle">0.039</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>GDS-VE, Geriatric Depression Scale (Spanish version).</p>
<p><italic>p</italic>&#x2009;&#x003C;&#x2009;0.001.</p>
<p>Own elaboration.</p>
</table-wrap-foot>
</table-wrap>
<p>Internal reliability &#x2013; calculated using KR-20 &#x2013; was 0.495 for GDS-5 and 0.715 for GDS-15. Convergent validity for GDS-5 and GDS-15 versus CASP-19 scale was <italic>r</italic><sub>s</sub>&#x2009;=&#x2009;&#x2212;0.447 (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.001) and de <italic>r</italic><sub>s</sub>&#x2009;=&#x2009;&#x2212;0.566 (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.001), respectively, which indicates a significant negative relationship for both study scales; discriminant validity versus SMCQ was <italic>r</italic><sub>s</sub>&#x2009;=&#x2009;&#x2212;0.046 (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.001) and de <italic>r</italic><sub>s</sub>&#x2009;=&#x2009;0.048 (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.001), respectively, with no significant relationship in any case (<xref rid="tab5" ref-type="table">Table 5</xref>).</p>
<table-wrap position="float" id="tab5">
<label>Table 5</label>
<caption>
<p>Convergent validity of GDS-VE5 and GDS-VE15 versus the CASP-19 scale and divergent validity versus the SMCQ scale.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th/>
<th/>
<th align="center" valign="top">CASP-19</th>
<th align="center" valign="top">SMCQ</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="middle" rowspan="3">GDS-15</td>
<td align="left" valign="middle">Spearman&#x2019;s correlation Sig. (bilateral)</td>
<td align="center" valign="middle">&#x2212;0.566&#x002A;&#x002A;</td>
<td align="center" valign="middle">0.048</td>
</tr>
<tr>
<td align="left" valign="middle">N</td>
<td align="center" valign="middle">0</td>
<td align="center" valign="middle">0.632</td>
</tr>
<tr>
<td/>
<td align="center" valign="middle">569</td>
<td align="center" valign="middle">569</td>
</tr>
<tr>
<td align="left" valign="middle" rowspan="3">GDS-5</td>
<td align="left" valign="middle">Spearman&#x2019;s correlation Sig. (bilateral)</td>
<td align="center" valign="middle">&#x2212;0.447&#x002A;&#x002A;</td>
<td align="center" valign="middle">&#x2212;0.046</td>
</tr>
<tr>
<td align="left" valign="middle">N</td>
<td align="center" valign="middle">0</td>
<td align="center" valign="middle">0.646</td>
</tr>
<tr>
<td/>
<td align="center" valign="middle">569</td>
<td align="center" valign="middle">569</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>GDS, Geriatric Depression Scale.</p>
<p>CASP-19, 19-item Control, Autonomy, Self-realization, Pleasure scale.</p>
<p>SMCQ, Subjective Memory Complaint Questionnaire.</p>
<p>&#x002A;&#x002A;<italic>p</italic>&#x2009;&#x003C;&#x2009;0.001.</p>
<p>Own elaboration.</p>
</table-wrap-foot>
</table-wrap>
<p>Sensitivity and specificity for GDS-5 &#x2013; with a cut-off point &#x2265;1 &#x2013; were, respectively, 0.517 and 0.650, while for GDS-15 &#x2013; with a cut-off point &#x2265;3 &#x2013; the sensitivity was 0.755 and the specificity 0.668. Regarding discriminative capacity, the ROC curve value for GDS-5 was 0.617 (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.001, with 95% confidence interval between 0.544 and 0.689); the ROC curve value for GDS-15 was 0.764 (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.001, with 95% confidence interval between 0.691 and 0.837).</p>
<p><xref rid="tab6" ref-type="table">Table 6</xref> shows the descriptive statistics of the items that make up the GDS-15 and GDS-5 scales. Thus, a positive skewness can be seen in items 1, 3, 7, 8, 11, and 14 on the GDS-15 scale and in items 1 and 3 of the GDS-5 scale, corresponding to items 1 and 8 of the GDS-15 scale.</p>
<table-wrap position="float" id="tab6">
<label>Table 6</label>
<caption>
<p>Descriptive statistics of the items that make up the GDS-15 and GDS-5.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Items</th>
<th align="center" valign="top">Mean</th>
<th align="center" valign="top">Standard deviation</th>
<th align="center" valign="top">Skewness</th>
<th align="center" valign="top">Kurtosis</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" colspan="5">GDS-15</td>
</tr>
<tr>
<td align="left" valign="top">1</td>
<td align="center" valign="top">0.069</td>
<td align="center" valign="top">0.255</td>
<td align="center" valign="top">3.385</td>
<td align="center" valign="top">9.493</td>
</tr>
<tr>
<td align="left" valign="top">2</td>
<td align="center" valign="top">0.460</td>
<td align="center" valign="top">0.498</td>
<td align="center" valign="top">0.158</td>
<td align="center" valign="top">&#x2212;1.982</td>
</tr>
<tr>
<td align="left" valign="top">3</td>
<td align="center" valign="top">0.146</td>
<td align="center" valign="top">0.354</td>
<td align="center" valign="top">2.004</td>
<td align="center" valign="top">2.021</td>
</tr>
<tr>
<td align="left" valign="top">4</td>
<td align="center" valign="top">0.294</td>
<td align="center" valign="top">0.456</td>
<td align="center" valign="top">0.902</td>
<td align="center" valign="top">&#x2212;1.191</td>
</tr>
<tr>
<td align="left" valign="top">5</td>
<td align="center" valign="top">0.226</td>
<td align="center" valign="top">0.419</td>
<td align="center" valign="top">1.308</td>
<td align="center" valign="top">&#x2212;0.291</td>
</tr>
<tr>
<td align="left" valign="top">6</td>
<td align="center" valign="top">0.406</td>
<td align="center" valign="top">0.491</td>
<td align="center" valign="top">0.381</td>
<td align="center" valign="top">&#x2212;1.961</td>
</tr>
<tr>
<td align="left" valign="top">7</td>
<td align="center" valign="top">0.153</td>
<td align="center" valign="top">0.360</td>
<td align="center" valign="top">1.927</td>
<td align="center" valign="top">1718</td>
</tr>
<tr>
<td align="left" valign="top">8</td>
<td align="center" valign="top">0.146</td>
<td align="center" valign="top">0.354</td>
<td align="center" valign="top">2.004</td>
<td align="center" valign="top">2.021</td>
</tr>
<tr>
<td align="left" valign="top">9</td>
<td align="center" valign="top">0.404</td>
<td align="center" valign="top">0.491</td>
<td align="center" valign="top">0.389</td>
<td align="center" valign="top">&#x2212;1.856</td>
</tr>
<tr>
<td align="left" valign="top">10</td>
<td align="center" valign="top">0.272</td>
<td align="center" valign="top">0.445</td>
<td align="center" valign="top">1.026</td>
<td align="center" valign="top">&#x2212;0.951</td>
</tr>
<tr>
<td align="left" valign="top">11</td>
<td align="center" valign="top">0.029</td>
<td align="center" valign="top">0.169</td>
<td align="center" valign="top">5.553</td>
<td align="center" valign="top">28.941</td>
</tr>
<tr>
<td align="left" valign="top">12</td>
<td align="center" valign="top">0.342</td>
<td align="center" valign="top">0.474</td>
<td align="center" valign="top">0.668</td>
<td align="center" valign="top">&#x2212;1.560</td>
</tr>
<tr>
<td align="left" valign="top">13</td>
<td align="center" valign="top">0.314</td>
<td align="center" valign="top">0.464</td>
<td align="center" valign="top">0.803</td>
<td align="center" valign="top">&#x2212;1.360</td>
</tr>
<tr>
<td align="left" valign="top">14</td>
<td align="center" valign="top">0.083</td>
<td align="center" valign="top">0.277</td>
<td align="center" valign="top">3.013</td>
<td align="center" valign="top">7.101</td>
</tr>
<tr>
<td align="left" valign="top">15</td>
<td align="center" valign="top">0.232</td>
<td align="center" valign="top">0.422</td>
<td align="center" valign="top">1.272</td>
<td align="center" valign="top">&#x2212;0.382</td>
</tr>
<tr>
<td align="left" valign="top" colspan="5">GDS-5</td>
</tr>
<tr>
<td align="left" valign="top">1</td>
<td align="center" valign="top">0.071</td>
<td align="center" valign="top">0.257</td>
<td align="center" valign="top">3.333</td>
<td align="center" valign="top">9.143</td>
</tr>
<tr>
<td align="left" valign="top">2</td>
<td align="center" valign="top">0.298</td>
<td align="center" valign="top">0.457</td>
<td align="center" valign="top">0.883</td>
<td align="center" valign="top">&#x2212;1.224</td>
</tr>
<tr>
<td align="left" valign="top">3</td>
<td align="center" valign="top">0.150</td>
<td align="center" valign="top">0.357</td>
<td align="center" valign="top">1.965</td>
<td align="center" valign="top">1.866</td>
</tr>
<tr>
<td align="left" valign="top">4</td>
<td align="center" valign="top">0.399</td>
<td align="center" valign="top">0.490</td>
<td align="center" valign="top">0.411</td>
<td align="center" valign="top">&#x2212;1.838</td>
</tr>
<tr>
<td align="left" valign="top">5</td>
<td align="center" valign="top">0.345</td>
<td align="center" valign="top">0.475</td>
<td align="center" valign="top">0.651</td>
<td align="center" valign="top">&#x2212;1.581</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>Own elaboration.</p>
</table-wrap-foot>
</table-wrap>
<p>The KMO statistic was 0.740 on the GDS-15 scale and 0.590 on the GDS-5 scale, while the Bartlett sphericity test was significant both on the GDS-15 scale (<italic>&#x03C7;</italic><sup>2</sup>&#x2009;=&#x2009;863.273; gl&#x2009;=&#x2009;105; <italic>p</italic>&#x2009;&#x003C;&#x2009;0.001) and the GDS-5 scale (<italic>&#x03C7;</italic><sup>2</sup>&#x2009;=&#x2009;75.697; gl&#x2009;=&#x2009;10; <italic>p</italic>&#x2009;&#x003C;&#x2009;0.001), indicating an underlying structure in both.</p>
<p>A first analysis, following the &#x201C;eigenvalue greater than 1,&#x201D; showed in the GDS-15 scale a structure of five factors that explained 51.04% of the variance. A first factor was defined that groups items 1 and 3, a second factor that groups items 6, 4, 14, 8, 2, and 9, a third factor that groups items 13 and 5, a fourth factor that groups items 10, 12, and 15, and a fifth factor that groups items 11 and 7. A second analysis showed a structure of 2 factors on the GDS-5 scale that explained 49.65% of the variance: a first factor that groups items 1 and 3 (items 1 and 8 of the GDS-15 scale) and a second factor that groups items 2, 4 and 5 (items 4, 9 and 12 of the GDS-15 scale). All items presented a load greater than 0.40, with the exception of items 2 and 9 on the GDS-15 scale.</p>
<p>Regarding the ceiling effect, this has not been evidenced in any of the scales, however, the floor effect has been present in the GDS-5 scale with 28.6%.</p>
</sec>
<sec id="sec10" sec-type="discussions">
<title>Discussion</title>
<p>We wanted an instrument to identify depression in people of an older age that would take into account psychometric properties. In this study, we aimed to validate and compare the 5- and 15- item GDSs in the Spanish population, analyzing their psychometric properties.</p>
<p>Regarding validation of the GDS-5 and GDS-15, different total scores are obtained for the variable sex, a significant positive relationship for the variable age, and a significant negative relationship for the variable years of schooling. Our results are in line with most works on the topic, were sex- (<xref ref-type="bibr" rid="ref8">de Dios del Valle et al., 2001</xref>; <xref ref-type="bibr" rid="ref23">Mart&#x00ED;nez de la Iglesia et al., 2002</xref>), age- (<xref ref-type="bibr" rid="ref9">De los Santos and Carmona Vald&#x00E9;s, 2018</xref>), and years of schooling-related (<xref ref-type="bibr" rid="ref9">De los Santos and Carmona Vald&#x00E9;s, 2018</xref>; <xref ref-type="bibr" rid="ref12">Gokcekuyu et al., 2022</xref>) differences are described. On the variables that act as predictors of total GDS-5 and GDS-15 scores, years of schooling and having a diagnosis of depression are common predictors for both scales. The independent variable age only acts as a predictor of total score for GDS-5 and the independent variable sex only as a predictor of total score for GDS-15.</p>
<p>The 0.715 and 0.495 internal reliability for GDS-15 and GDS-5, respectively, indicates that the fewer the number of items in the scale lesser the internal reliability. Our values are similar to the work by <xref ref-type="bibr" rid="ref8">de Dios del Valle et al. (2001)</xref>, who reported an internal reliability of 0.79 and 0.45 for GDS-15 and GDS-5, respectively, far from the 0.99 found by <xref ref-type="bibr" rid="ref23">Mart&#x00ED;nez de la Iglesia et al. (2002)</xref> for GDS-15. The abovementioned studies were done on Spanish populations. The high internal reliability reported by <xref ref-type="bibr" rid="ref23">Mart&#x00ED;nez de la Iglesia et al. (2002)</xref> may imply the existence of superfluous items that disregard relevant information about the features to be measured (<xref ref-type="bibr" rid="ref3">Barrios and Cosculluela, 2013</xref>).</p>
<p>GDS-15 is suitable as a screening instrument to detect the possible presence of depression in people of an older age with adequate sensitivity (78.5%) and acceptable specificity (66.8%) for a cut-off value of 3. GDS-5 has a relatively low sensitivity and acceptable specificity, contrary to what has been reported elsewhere (<xref ref-type="bibr" rid="ref8">de Dios del Valle et al., 2001</xref>; <xref ref-type="bibr" rid="ref28">Ortega Orcos et al., 2007</xref>). The diagnostic capacity of the scale significantly worsens when the length of the scale is reduced, same as reported by <xref ref-type="bibr" rid="ref15">Izal et al. (2007)</xref>.</p>
<p>The 5-factor structure found in the GDS-15 scale is different from the two-factor structure found by <xref ref-type="bibr" rid="ref19">Lucas-Carrasco (2012)</xref> in cognitively healthy subjects and more similar to the four-factor structure found by <xref ref-type="bibr" rid="ref33">Weintraub et al. (2007)</xref> in subjects with mild dementia. Undoubtedly, this is a topic that should be studied in depth in order to obtain an instrument with a well-defined factorial structure that leads to significant clinical utility in the future.</p>
<p>There are some limitations to this study. On the one hand, the diagnosis of depression was accepted as such only considering the self-report of the evaluated person. There was no rigorous evaluation of study participants by a member of our research team to confirm the possible diagnosis of depression or identify depression in subjects without a clear diagnosis, or who hid their condition. On the other hand, another limitation is the possible existence of a cohort effect. Here, we tried to overcome the possible existence of this effect &#x2013; detected in previous studies &#x2013; aiming to validate the scales for the Spanish population (<xref ref-type="bibr" rid="ref8">de Dios del Valle et al., 2001</xref>; <xref ref-type="bibr" rid="ref23">Mart&#x00ED;nez de la Iglesia et al., 2002</xref>; <xref ref-type="bibr" rid="ref15">Izal et al., 2007</xref>; <xref ref-type="bibr" rid="ref28">Ortega Orcos et al., 2007</xref>). However, while we expect the possible overcoming, our study may inherently carry the same cohort effect, which in turn will have to be overcome in further validations with a different cohort.</p>
</sec>
<sec id="sec11" sec-type="conclusions">
<title>Conclusion</title>
<p>The evidence in this work indicates that GDS-15, and to a greater extent GDS-5, should be revised or even reformulated to improve their diagnostic usefulness by choosing higher discriminative ability items or even include new items with greater sensitivity that consider currently prevailing psychosocial factors.</p>
<p>Likewise, it must be made clear that the usefulness of the scales is merely to screen for the existence of a possible depressive syndrome, since the confirmation of the diagnosis is exclusively clinical, through an interview conducted by a trained professional.</p>
</sec>
<sec id="sec12" sec-type="data-availability">
<title>Data availability statement</title>
<p>The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.</p>
</sec>
<sec id="sec13">
<title>Ethics statement</title>
<p>Ethical review and approval were not required for the study of human participants in accordance with the local legislation and institutional requirements. Written informed consent was obtained from all participants.</p>
</sec>
<sec id="sec14">
<title>Author contributions</title>
<p>CB-C and CD-D: conception or design of the work. AP: data collection. MP-L, MF-I, and LA-R: data analysis and interpretation. LA-R: drafting the article. MG-C: critical revision of the article. CD-D: final approval of the version to be publish. All authors contributed to the article and approved the submitted version.</p>
</sec>
<sec id="sec15" sec-type="funding-information">
<title>Funding</title>
<p>This work was supported by Grant PID2020-115137RB-I00 funded by MCIN/AEI/10.13039/501100011033.</p>
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