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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Psychol.</journal-id>
<journal-title>Frontiers in Psychology</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Psychol.</abbrev-journal-title>
<issn pub-type="epub">1664-1078</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpsyg.2022.897426</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Psychology</subject>
<subj-group>
<subject>Mini Review</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Investigating the Obsessive and Compulsive Features of Cyberchondria: A Holistic Review</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Yang</surname><given-names>Yi</given-names></name>
<xref rid="aff1" ref-type="aff"><sup>1</sup></xref>
<xref rid="fn0001" ref-type="author-notes"><sup>&#x2020;</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/1386845/overview"/>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Ta</surname><given-names>Na</given-names></name>
<xref rid="aff2" ref-type="aff"><sup>2</sup></xref>
<xref rid="c001" ref-type="corresp"><sup>&#x002A;</sup></xref>
<xref rid="fn0001" ref-type="author-notes"><sup>&#x2020;</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/1344734/overview"/>
</contrib>
<contrib contrib-type="author"><name><surname>Li</surname><given-names>Zhanghao</given-names></name>
<xref rid="aff3" ref-type="aff"><sup>3</sup></xref>
<xref rid="aff4" ref-type="aff"><sup>4</sup></xref>
<xref rid="fn0001" ref-type="author-notes"><sup>&#x2020;</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/1386874/overview"/>
</contrib>
</contrib-group>
<aff id="aff1"><sup>1</sup><institution>School of Chinese Culture and Communication, Beijing International Studies University</institution>, <addr-line>Beijing</addr-line>, <country>China</country></aff>
<aff id="aff2"><sup>2</sup><institution>School of Journalism and Communication, Renmin University of China</institution>, <addr-line>Beijing</addr-line>, <country>China</country></aff>
<aff id="aff3"><sup>3</sup><institution>Computational Communication Research Center, Beijing Normal University</institution>, <addr-line>Zhuhai</addr-line>, <country>China</country></aff>
<aff id="aff4"><sup>4</sup><institution>School of Journalism and Communication, Beijing Normal University</institution>, <addr-line>Beijing</addr-line>, <country>China</country></aff>
<author-notes>
<fn id="fn0002" fn-type="edited-by">
<p>Edited by: Jes&#x00FA;s-Nicasio Garc&#x00ED;a-S&#x00E1;nchez, Universidad de Le&#x00F3;n, Spain</p>
</fn>
<fn id="fn0003" fn-type="edited-by">
<p>Reviewed by: Nabi Nazari, Lorestan University, Iran; Andrei Corneliu Holman, Alexandru Ioan Cuza University, Romania; Han Zheng, Nanyang Technological University, Singapore</p>
</fn>
<corresp id="c001">&#x002A;Correspondence: Na Ta, <email>tanayun@ruc.edu.cn</email></corresp>
<fn id="fn0001">
<p><sup>&#x2020;</sup>These authors have contributed equally to this work</p>
</fn>
<fn id="fn0004" fn-type="other">
<p>This article was submitted to Personality and Social Psychology, a section of the journal Frontiers in Psychology</p>
</fn>
</author-notes>
<pub-date pub-type="epub">
<day>04</day>
<month>07</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="collection">
<year>2022</year>
</pub-date>
<volume>13</volume>
<elocation-id>897426</elocation-id>
<history>
<date date-type="received">
<day>16</day>
<month>03</month>
<year>2022</year>
</date>
<date date-type="accepted">
<day>13</day>
<month>06</month>
<year>2022</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2022 Yang, Ta and Li.</copyright-statement>
<copyright-year>2022</copyright-year>
<copyright-holder>Yang, Ta and Li</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<sec>
<title>Background</title>
<p>Cyberchondria has been brought into sharp focus during the COVID-19 health emergency; it refers to individuals who obsessively and compulsively search for health information online, resulting in excessive health concerns. Recent scholarship focuses on its obsessive and compulsive aspect, following a biopsychosocial approach as opposed to a pathology of health anxiety. It lacks interpretation of the socio-psychological dynamics between the dimensions.</p>
</sec>
<sec>
<title>Objective</title>
<p>This review aims to propose a holistic view toward understanding cyberchondria as an obsessive&#x2013;compulsive syndrome and considers possible interventions. It specifically seeks to explain cyberchondria from diversified mediator variables and to pinpoint connections between each perspective.</p>
</sec>
<sec>
<title>Methodology</title>
<p>Comprehensive searches of databases such as <italic>PubMed</italic> and <italic>Springer</italic> were conducted to identify English articles relating to cyberchondria from 2001 to 2022. Based on a systematic filtering process, 27 articles were finally reviewed.</p>
</sec>
<sec>
<title>Findings</title>
<p>The authors compare and confirm three forecasts to predict cyberchondria, associating it with individual metacognition, uncertainty of unverified information, and algorithm-driven, biased information environments.</p>
</sec>
<sec>
<title>Value</title>
<p>Theoretically, a holistic framework is proposed to explain the obsessive and compulsive features of cyberchondria. Clinically, the research calls for more professional psychoeducation and chain screening of cyberchondria and other psychological disorders. Socially, it promotes support for risk-sensitive, information-deficient groups during pandemics like COVID-19. It also stresses more careful use of algorithm-driven search engine technology for platforms delivering medical information. Future research may explore areas such as the association between cyberchondria and other social-related disorders, as well as correlations among cyberchondria, obsessive and compulsive disorders, medical trust, and algorithm-driven search results.</p>
</sec>
</abstract>
<kwd-group>
<kwd>cyberchondria</kwd>
<kwd>metacognition</kwd>
<kwd>unverified information</kwd>
<kwd>biased information environment</kwd>
<kwd>obsessive and compulsive searching</kwd>
</kwd-group>
<contract-num rid="cn1">KYQH22A008</contract-num>
<contract-num rid="cn2">21BXW061</contract-num>
<contract-sponsor id="cn1">2022 New Teaching Staff Scientific Research Initiative Plan of Beijing International Studies University</contract-sponsor>
<contract-sponsor id="cn2">Chinese National Social Science Foundation</contract-sponsor>
<counts>
<fig-count count="2"/>
<table-count count="2"/>
<equation-count count="0"/>
<ref-count count="49"/>
<page-count count="11"/>
<word-count count="6866"/>
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</article-meta>
</front>
<body>
<sec id="sec6" sec-type="intro">
<title>Introduction</title>
<p>The COVID-19 pandemic and its numerous and varied symptomologies have spawned an epidemic of online symptom-checking, resulting in a crisis of psychological wellbeing within the public and spotlighting the condition of cyberchondria. Cyberchondria features compulsive online researching of health-related symptoms (<xref ref-type="bibr" rid="ref16">Fergus and Spada, 2017</xref>; <xref ref-type="bibr" rid="ref30">Newby and McElroy, 2020</xref>). Existing studies, under the COVID-19 pandemics, interpret cyberchondria with three different models (<xref rid="fig1" ref-type="fig">Figure 1</xref>). In the pathology model, cyberchondria is treated as a sub-symptom of health anxiety. Studies demonstrate that health anxiety is positively associated with online health information seeking (OHIS), resulting in cyberchondria (<xref ref-type="bibr" rid="ref26">Mathes et al., 2018</xref>; <xref ref-type="bibr" rid="ref27">McMullan et al., 2019</xref>). Conversely, the other two models explain cyberchondria within the obsessive&#x2013;compulsive disorder (OCD) framework. They also consider health anxiety but place more importance on the repeated online health-related searches and their antecedents. In the hybrid model, the condition is understood as an escalating distress that eventually develops into cyberchondria&#x2014;generated due to uncontrollable worries about illness and excessive and compulsive searching behaviors (<xref ref-type="bibr" rid="ref10">Brown et al., 2019</xref>). Significantly, in the integrative model, <xref ref-type="bibr" rid="ref53">Zheng et al. (2021)</xref> proved that negative metacognitive beliefs could function as a boundary condition for regular OHIS, resulting in cyberchondria.</p>
<fig position="float" id="fig1">
<label>Figure 1</label>
<caption>
<p>The PRISMA flow diagram of the studies included in this review.</p>
</caption>
<graphic xlink:href="fpsyg-13-897426-g001.tif"/>
</fig>
<p>Our review also focus on the obsessive and compulsive dimension of cyberchondria rather than regarding it as a single pathology; however, our review differs from the hybrid and integrative models. The former centers on how health beliefs might impact OHIS but fails to analyze the development dynamics of cyberchondria. The latter follows a behaviorism approach, emphasizing a concrete process during which online-seeking behaviors generate effects; however, relevant studies lack in analyses of the interconnections between each antecedent and its associations with cyberchondria. The following OCD studies on cyberchondria inspire us to propose a more holistic view. <xref ref-type="bibr" rid="ref54">Zheng et al. (2020)</xref> identify psychological risk factors, information factors, and personality traits associated with cyberchondria. Others suggest a biopsychosocial approach. Physically, a threatening interpretation of bodily sensations or benign symptoms might increase bodily sensations&#x2014;such as increased heart rate or sweating&#x2014;during online searches, and develop into cyberchondria (<xref ref-type="bibr" rid="ref51">Witth&#x00F6;ft and Hiller, 2010</xref>). Psychologically, individuals with anxiety traits are more likely to become anxious about viruses, leading to cyberchondria (<xref ref-type="bibr" rid="ref23">Jungmann and Witth&#x00F6;ft, 2020</xref>). Socially, users&#x2019; online exposures to threatening medical information, regardless of whether they had health anxiety before OHIS, could increase cyberchondria (<xref ref-type="bibr" rid="ref47">Vismara et al., 2020</xref>). Drawn on these studies, our review attempts to explain the interconnected relationships between the cognitive, social, and technical antecedents.</p>
<p>Understanding cyberchondria under an OCD framework also highlights its public health significance in this digital age with a populace suffering from pandemics. It emphasizes excessive and repeated online health-related searches, shedding light on the paradoxical role of the internet during this period of long-distance socialization, quarantine, and isolation. <xref ref-type="bibr" rid="ref52">Wu et al. (2021)</xref> illustrate how repeated online media consumption during the pandemic amplifies individual anxiety and fear, leading to cyberchondria. The internet is unquestionably an information resource, but it also contributes to public anxiety and distrust of unverified information, as well as vulnerabilities perceived by users due to biased search results shaped by algorithm-driven technologies. As such, this review will also provide novel analyses on how the emerging algorithm-driven search engine technologies shape biased information environments that impact cyberchondria.</p>
</sec>
<sec id="sec7">
<title>Question and Objective</title>
<p>This targeted review<xref rid="fn0005" ref-type="fn"><sup>1</sup></xref> closely examines one question: Is there a holistic view that explains cyberchondria as an OCD beyond a single pathology?</p>
<p>Based on peer-reviewed published articles in this field, this work aims to compare different research foci to build an informative analysis of literature on the obsessive and compulsive feature of cyberchondria. It specifically endeavors to clearly highlight the main results that emerged in each area, as well as to pinpoint potential connections between them&#x2014;ways in which they could be combined to advance the understanding of cyberchondria and the possible interventions.</p>
</sec>
<sec id="sec8">
<title>Method and Design</title>
<p>The authors conducted a comprehensive search of five databases consisting of health-related studies across multiple disciplines: one medical science databases (PubMed), four comprehensive databases (Taylor &#x0026; Francis, Springer, Elsevier) and one information technology database (DBLP).</p>
<p>The search term &#x201C;cyberchondria&#x201D;<xref rid="fn0006" ref-type="fn"><sup>2</sup></xref> was applied to titles, abstracts, and keyword fields to filter out irrelevant studies. The screening criteria were peer-reviewed English articles published that regard cyberchondria as an OCD rather than a sub-symptom of health anxiety. Reference lists of the included papers were also checked for inclusiveness. <xref rid="fig1" ref-type="fig">Figure 1</xref> shows the PRISMA flowchart of the literature screening process.</p>
<p>Three authors examined these articles separately and agreed on the final sample of 27 published from 2001 to 2022, from which the following information was extracted: source, database, method, and main findings. The authors also categorized samples and summarized three perspectives: cognitive, social, and technological. All information is identified in <xref rid="tab1" ref-type="table">Table 1</xref>.</p>
<table-wrap position="float" id="tab1">
<label>Table 1</label>
<caption>
<p>The final sample of literature reviewed in this article.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Source</th>
<th align="left" valign="top">Database</th>
<th align="center" valign="top">Citation</th>
<th align="center" valign="top">IF</th>
<th align="left" valign="top">Method</th>
<th align="left" valign="top">Keyword</th>
<th align="left" valign="top">Main findings</th>
<th align="left" valign="top">Perspective</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref5">Bailey and Wells, 2015</xref>&#x002A;</td>
<td align="char" valign="top" char="&#x00B1;">PubMed</td>
<td align="char" valign="top" char="&#x00B1;">42</td>
<td align="char" valign="top" char="&#x00B1;">3.222</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">Metacognition, health anxiety, exploratory factor analysis, confirmatory factor analysis, and validity</td>
<td align="char" valign="top" char="&#x00B1;">It reports on the development and initial evaluation of a new specific metacognitive measure of health anxiety, the Metacognitions Questionnaire-Health Anxiety (MCQ-HA).</td>
<td align="char" valign="top" char="&#x00B1;" rowspan="7">Cognitive</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref6">Bajcar and Babiak, 2020</xref></td>
<td align="char" valign="top" char="&#x00B1;">Elsevier</td>
<td align="char" valign="top" char="&#x00B1;">9</td>
<td align="char" valign="top" char="&#x00B1;">3.004</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">Cyberchondria, neuroticism, intolerance of uncertainty, defensive pessimism, and mediation model</td>
<td align="char" valign="top" char="&#x00B1;">Results have revealed that, of the FFM personality traits, only neuroticism was associated with cyberchondria. The effect of neuroticism on cyberchondria was confirmed</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref16">Fergus and Spada, 2017</xref></td>
<td align="char" valign="top" char="&#x00B1;">PubMed</td>
<td align="char" valign="top" char="&#x00B1;">77</td>
<td align="char" valign="top" char="&#x00B1;">2.938</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">Anxiety sensitivity, cyberchondria, intolerance of uncertainty, metacognition, metacognitive beliefs, and problematic internet use</td>
<td align="char" valign="top" char="&#x00B1;">Cyberchondria shared a moderate to strong association with problematic Internet use and metacognitive beliefs.</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref17">Fergus and Spada, 2018</xref>&#x002A;</td>
<td align="char" valign="top" char="&#x00B1;">PubMed</td>
<td align="char" valign="top" char="&#x00B1;">38</td>
<td align="char" valign="top" char="&#x00B1;">5.264</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">Cyberchondria, beliefs about rituals, health anxiety, metacognitive beliefs, and stop signals</td>
<td align="char" valign="top" char="&#x00B1;">Beliefs about rituals and stop signals emerged as relatively specific to cyberchondria versus health anxiety, which preliminary support for a metacognitive conceptualization of cyberchondria</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref23">Jungmann and Witth&#x00F6;ft, 2020</xref></td>
<td align="char" valign="top" char="&#x00B1;">Elsevier</td>
<td align="char" valign="top" char="&#x00B1;">279</td>
<td align="char" valign="top" char="&#x00B1;">5.264</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">Cyberchondria, COVID-19, emotion regulation, health anxiety, and virus anxiety</td>
<td align="char" valign="top" char="&#x00B1;">Cyberchondria Pandemic showed positive correlations with current virus anxiety, and this relationship was additionally moderated by trait health anxiety. A negative correlation was found between the perception of being informed about the pandemic and the current virus anxiety.</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref34">Oniszczenko, 2021</xref>&#x002A;</td>
<td align="char" valign="top" char="&#x00B1;">PubMed</td>
<td align="char" valign="top" char="&#x00B1;">4</td>
<td align="char" valign="top" char="&#x00B1;">3.240</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">-</td>
<td align="char" valign="top" char="&#x00B1;">Cyberchondria positively correlated with both COVID-19 fears scales, though the correlation coefficients were medium. Based on the results of linear regression analysis, only anxious temperament and COVID-19 fear of self-infection were significant predictors of cyberchondria.</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref01">Sofia et al., 2022</xref></td>
<td align="char" valign="top" char="&#x00B1;">PubMed</td>
<td align="char" valign="top" char="&#x00B1;">0</td>
<td align="char" valign="top" char="&#x00B1;">2.885</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">Cyberchondria, health anxiety, health cognitions, and metacognitions about health anxiety</td>
<td align="char" valign="top" char="&#x00B1;">Metacognition about health anxiety relating to beliefs about the uncontrollability of thoughts was the only significant predictor of prospective cyberchondria scores when controlling for health anxiety.</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref53">Zheng et al., 2021</xref></td>
<td align="char" valign="top" char="&#x00B1;">Elsevier</td>
<td align="char" valign="top" char="&#x00B1;">6</td>
<td align="char" valign="top" char="&#x00B1;">6.182</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">Cyberchondria, information insufficiency, health anxiety, online health information seeking, and negative metacognitive beliefs</td>
<td align="char" valign="top" char="&#x00B1;">This study further identifies negative metacognitive beliefs as a boundary condition for how regular OHIS results in cyberchondria.</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref2">Allen et al., 2014</xref></td>
<td align="char" valign="top" char="&#x00B1;">Springer</td>
<td align="char" valign="top" char="&#x00B1;">164</td>
<td align="char" valign="top" char="&#x00B1;">4.344</td>
<td align="char" valign="top" char="&#x00B1;">Mixed method</td>
<td align="char" valign="top" char="&#x00B1;">Inter-organizational information systems, information sharing, activity theory, and emergency response</td>
<td align="char" valign="top" char="&#x00B1;">Online sharing and communication have a proven positive on the recovery of individual in crisis.</td>
<td align="char" valign="top" char="&#x00B1;" rowspan="8">Social</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref9">Bora et al., 2018</xref></td>
<td align="char" valign="top" char="&#x00B1;">Taylor &#x0026; Francis</td>
<td align="char" valign="top" char="&#x00B1;">107</td>
<td align="char" valign="top" char="&#x00B1;">3.802</td>
<td align="char" valign="top" char="&#x00B1;">Content analysis</td>
<td align="char" valign="top" char="&#x00B1;">Public health, internet, social media, health communication, health information, and pandemic</td>
<td align="char" valign="top" char="&#x00B1;">Misinformation will be spread more quickly than information during a public health event and further threaten people&#x2019;s mental health.</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref11">Cinelli et al., 2020</xref></td>
<td align="char" valign="top" char="&#x00B1;">PubMed</td>
<td align="char" valign="top" char="&#x00B1;">1,125</td>
<td align="char" valign="top" char="&#x00B1;">4.13</td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">-</td>
<td align="char" valign="top" char="&#x00B1;">Information spreading is driven by the interaction paradigm imposed by the specific social media or/and by the specific interaction patterns of groups of users engaged with the topic.</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref25">Maftei and Holman, 2020</xref>&#x002A;</td>
<td align="char" valign="top" char="&#x00B1;">Taylor &#x0026; Francis</td>
<td align="char" valign="top" char="&#x00B1;">21</td>
<td align="char" valign="top" char="&#x00B1;">2.990</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">Cyberchondria, coronavirus, neuroticism, optimism, and age</td>
<td align="char" valign="top" char="&#x00B1;">Among elderly participants, the psychologically protective influence of optimism against cyberchondria emerged as larger than the opposite effect of neuroticism.</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref02">McElroy et al., 2019</xref>&#x002A;</td>
<td align="char" valign="top" char="&#x00B1;">PubMed</td>
<td align="char" valign="top" char="&#x00B1;">10</td>
<td align="char" valign="top" char="&#x00B1;">4.157</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">Cyberchondria, health anxiety, self-diagnosis, and general anxiety</td>
<td align="char" valign="top" char="&#x00B1;">Cyberchondria Severity Scale (CSS 12) highlighted four indicators, coercion, suffering, excess, seeking comfort.</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref36">Parsons and Alden, 2022</xref>&#x002A;</td>
<td align="char" valign="top" char="&#x00B1;">Elsevier</td>
<td align="char" valign="top" char="&#x00B1;">0</td>
<td align="char" valign="top" char="&#x00B1;">1.418</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">Obsessive&#x2013;compulsive disorder, reassurance-seeking, shame, fear of self, and cyberchondria</td>
<td align="char" valign="top" char="&#x00B1;">This research identifies symptoms and characteristics that may be linked to more frequent online reassurance-seeking in particular. Unacceptable thoughts appear uniquely related to reassurance-seeking from non-interactive online sources.</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref37">Patwary et al., 2021</xref></td>
<td align="char" valign="top" char="&#x00B1;">PubMed</td>
<td align="char" valign="top" char="&#x00B1;">1</td>
<td align="char" valign="top" char="&#x00B1;">3.044</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">Information source trust, coronavirus, SARS-CoV-2, mental health, COVID-19 stressor, and Global south</td>
<td align="char" valign="top" char="&#x00B1;">Trusting social media to provide accurate COVID-19 information may exacerbate poor mental health, while trusting traditional media (i.e., television, radio, and the newspaper) may have stress-buffering effects.</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref39">Rovetta and Bhagavathula, 2020</xref></td>
<td align="char" valign="top" char="&#x00B1;">PubMed</td>
<td align="char" valign="top" char="&#x00B1;">88</td>
<td align="char" valign="top" char="&#x00B1;">5.43</td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">COVID-19, coronavirus, Google, Instagram, infodemiology, infodemic, and social media</td>
<td align="char" valign="top" char="&#x00B1;">Globally, there is a growing interest in COVID-19, and numerous infodemic monikers continue to circulate on the Internet.</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref43">Starcevic et al., 2020a</xref></td>
<td align="char" valign="top" char="&#x00B1;">PubMed</td>
<td align="char" valign="top" char="&#x00B1;">38</td>
<td align="char" valign="top" char="&#x00B1;">N.A.</td>
<td align="char" valign="top" char="&#x00B1;">Theoretical research</td>
<td align="char" valign="top" char="&#x00B1;">COVID-19, cyberchondria, information overload, intolerance of uncertainty, online health information, online health information literacy, online health searching, public health, reassurance seeking, and uncertainty</td>
<td align="char" valign="top" char="&#x00B1;">This model of cyberchondria during the COVID19 pandemic contributes to the literature by helping to understand the hypothesized rise in cyberchondria during public health emergencies and formulate a framework for prevention of cyberchondria and effective responding to it.</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref44">Starcevic et al., 2020b</xref></td>
<td align="char" valign="top" char="&#x00B1;">PubMed</td>
<td align="char" valign="top" char="&#x00B1;">35</td>
<td align="char" valign="top" char="&#x00B1;">5.285</td>
<td align="char" valign="top" char="&#x00B1;">Theoretical research</td>
<td align="char" valign="top" char="&#x00B1;">Cyberchondria, online health research, reassurance seeking, health anxiety, problematic internet use, and compulsivity</td>
<td align="char" valign="top" char="&#x00B1;">Most definitions of cyberchondria emphasize online health research associated with heightened distress or anxiety. The two theoretical models of cyberchondria involve reassurance seeking and specific metacognitive beliefs.</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref3">Azzopardi et al., 2018</xref>&#x002A;</td>
<td align="char" valign="top" char="&#x00B1;">DBLP</td>
<td align="char" valign="top" char="&#x00B1;">36</td>
<td align="char" valign="top" char="&#x00B1;">8.740</td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">-</td>
<td align="char" valign="top" char="&#x00B1;">Search engines prioritize ranking over relevance to generate SERP, to improve the click through rate. Serious and negative health information in SERP have increased click through rate due to their high ranking.</td>
<td align="char" valign="top" char="&#x00B1;" rowspan="9">Technological</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref18">Gao and Shah, 2020</xref>&#x002A;</td>
<td align="char" valign="top" char="&#x00B1;">DBLP</td>
<td align="char" valign="top" char="&#x00B1;">46</td>
<td align="char" valign="top" char="&#x00B1;">6.222</td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">Information retrieval, search engine bias, fairness ranking, relevance, diversity, and novelty</td>
<td align="char" valign="top" char="&#x00B1;">The ranking of the results in Search Engine Result Pages (SERP), especially by top-level search engines, is unbalanced and does not conform with the general diversity distribution.</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref19">Gezici et al., 2021</xref>&#x002A;</td>
<td align="char" valign="top" char="&#x00B1;">DBLP</td>
<td align="char" valign="top" char="&#x00B1;">3</td>
<td align="char" valign="top" char="&#x00B1;">2.293</td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">Bias evaluation, fair ranking, search bias, and web search</td>
<td align="char" valign="top" char="&#x00B1;">Search engines are not necessarily neutral. Different search engines may have different ideological biases and present different search results to users.</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref22">Joachims et al., 2017</xref></td>
<td align="char" valign="top" char="&#x00B1;">DBLP</td>
<td align="char" valign="top" char="&#x00B1;">75</td>
<td align="char" valign="top" char="&#x00B1;">8.740</td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">Implicit feedback, eyetracking, WWW search, and clickthrough</td>
<td align="char" valign="top" char="&#x00B1;">Internet users tend to click on top-ranking results, and are more likely to trust them, thus maintaining the ranking of these websites.</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref29">Muussesa et al., 2014</xref></td>
<td align="char" valign="top" char="&#x00B1;">DBLP</td>
<td align="char" valign="top" char="&#x00B1;">108</td>
<td align="char" valign="top" char="&#x00B1;">6.829</td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">Compulsive internet use, psychological wellbeing, happiness, depression, and loneliness</td>
<td align="char" valign="top" char="&#x00B1;">Compulsive Internet Use (CIU) predicted increases in depression, loneliness and stress over time, and a decrease in happiness. No effect of CIU on the change in self-esteem was found. Further, happiness predicted a decrease in CIU over time.</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref40">Schoenherr and White, 2014</xref></td>
<td align="char" valign="top" char="&#x00B1;">DBLP</td>
<td align="char" valign="top" char="&#x00B1;">5</td>
<td align="char" valign="top" char="&#x00B1;">8.740</td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">Health search, medical search, diagnosis, log/behavioral analysis, and cyberchondria</td>
<td align="char" valign="top" char="&#x00B1;">Based on exposure to online content, people may develop undue health concerns, believing that common and benign symptoms are explained by serious illnesses.</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref41">Schulthei&#x00DF; and Lewandowski, 2021</xref>&#x002A;</td>
<td align="char" valign="top" char="&#x00B1;">DBLP</td>
<td align="char" valign="top" char="&#x00B1;">2</td>
<td align="char" valign="top" char="&#x00B1;">3.282</td>
<td align="char" valign="top" char="&#x00B1;">Online survey</td>
<td align="char" valign="top" char="&#x00B1;">Information literacy, online survey, search engines, and user trust</td>
<td align="char" valign="top" char="&#x00B1;">Users strongly trust Google, yet they are unable to adequately evaluate its search results. Users with little search engine knowledge are more likely to trust and use Google than users with more knowledge.</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref46">Virginia et al., 2021</xref></td>
<td align="char" valign="top" char="&#x00B1;">DBLP</td>
<td align="char" valign="top" char="&#x00B1;">0</td>
<td align="char" valign="top" char="&#x00B1;">N.A.</td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">Application, information retrieval, reranking, and search engine</td>
<td align="char" valign="top" char="&#x00B1;">Search engine algorithms attach importance to the relationship between user click behavior and result ordering. Internet users tend to click on top-ranking results.</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref50">White and Horvitz, 2013</xref></td>
<td align="char" valign="top" char="&#x00B1;">DBLP</td>
<td align="char" valign="top" char="&#x00B1;">19</td>
<td align="char" valign="top" char="&#x00B1;">2.043</td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">Captions, biases, diagnostic search, and cyberchondria</td>
<td align="char" valign="top" char="&#x00B1;">Users are significantly more likely to examine and click on captions containing potentially-alarming medical terminology such as &#x201C;heart attack&#x201D; or &#x201C;medical emergency&#x201D; independent of result rank position.</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p><italic>An asterisk (&#x002A;) indicates that this article is of greater importance than others. A short line (-) indicates there are no keyword in this article</italic>.</p>
</table-wrap-foot>
</table-wrap>
<p>Based on the literature review, the authors further compared three forecasts to predict cyberchondria.</p>
<sec id="sec9">
<title>Forecast One</title>
<p>Cyberchondria is associated with problematic Internet use driven by an individual&#x2019;s metacognition of the state of health.</p>
</sec>
<sec id="sec10">
<title>Forecast Two</title>
<p>Cyberchondria is associated with the escalating distress resulting from the unverifiable information produced when searching online information for reassurance.</p>
</sec>
<sec id="sec11">
<title>Forecast Three</title>
<p>Cyberchondria is associated with a biased information environment due to manipulated algorithm-driven search technologies.</p>
</sec>
</sec>
<sec id="sec12" sec-type="results">
<title>Results</title>
<sec id="sec13">
<title>Quality Assessment of Articles Included<xref rid="fn0007" ref-type="fn"><sup>3</sup></xref>
</title>
<p>Three authors conducted a comprehensive evaluation of the 27 included papers from seven aspects, including study design, the number of participants/groups, outcome measure, quality of intervention, suggesting possible intervention, quality of reporting, and generalizability. Seventeen papers were evaluated as of high quality in all aspects. Two papers did not carry out empirical research but provided theoretical-driven models to inspire further study on the obsessive and compulsive quality of cyberchondria. As many papers adopt method of questionnaire survey, some of them had a moderate performance in the choice of outcome measure and the quality of the intervention. See <xref rid="tab2" ref-type="table">Table 2</xref> for more details on the quality assessment.</p>
<table-wrap position="float" id="tab2">
<label>Table 2</label>
<caption>
<p>Quality assessment of article included.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="middle">Source</th>
<th align="left" valign="middle">Method</th>
<th align="left" valign="middle">Research design</th>
<th align="left" valign="middle">Number of participants/groups</th>
<th align="left" valign="middle">Choice of outcome measure</th>
<th align="left" valign="middle">Quality of the intervention</th>
<th align="left" valign="middle">Suggesting possible intervention</th>
<th align="left" valign="middle">Quality of reporting</th>
<th align="left" valign="middle">Generalisability</th>
<th align="left" valign="middle">Perspective</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref5">Bailey and Wells, 2015</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic><sub>1</sub> =&#x2009;351; <italic>N</italic><sub>2</sub> =&#x2009;553; <italic>N</italic><sub>3</sub> =&#x2009;259</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;" rowspan="8">Cognitive</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref6">Bajcar and Babiak, 2020</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic><sub>1</sub> =&#x2009;381; <italic>N</italic><sub>2</sub> =&#x2009;355</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref16">Fergus and Spada, 2017</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic><sub>1</sub> =&#x2009;337; <italic>N</italic><sub>2</sub> =&#x2009;260</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref17">Fergus and Spada, 2018</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic><sub>1</sub> =&#x2009;330; <italic>N</italic><sub>2</sub> =&#x2009;331</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref23">Jungmann and Witth&#x00F6;ft, 2020</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic> =&#x2009;1,615</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref34">Oniszczenko, 2021</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic> =&#x2009;499</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref01">Sofia Airoldi et al., 2022</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic> =&#x2009;125</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref53">Zheng et al., 2021</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic> =&#x2009;426</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref2">Allen et al., 2014</xref></td>
<td align="char" valign="top" char="&#x00B1;">Mixed method</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">N.A.</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;" rowspan="10">Social</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref9">Bora et al., 2018</xref></td>
<td align="char" valign="top" char="&#x00B1;">Content analysis</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic> =&#x2009;101 videos</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref11">Cinelli et al., 2020</xref></td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">1,342,103 posts; 7,465,721 comments produced by 3,734,815 users</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref25">Maftei and Holman, 2020</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic> =&#x2009;880</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref02">McElroy et al., 2019</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic> =&#x2009;208</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref36">Parsons and Alden, 2022</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic> =&#x2009;459</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref37">Patwary et al., 2021</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;"><italic>N</italic> =&#x2009;744</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref39">Rovetta and Bhagavathula, 2020</xref></td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">2,918,000 Hashtags</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref43">Starcevic et al., 2020a</xref></td>
<td align="char" valign="top" char="&#x00B1;">Theoretical research</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">N.A.</td>
<td align="char" valign="top" char="&#x00B1;">N.A.</td>
<td align="char" valign="top" char="&#x00B1;">N.A.</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref44">Starcevic et al., 2020b</xref></td>
<td align="char" valign="top" char="&#x00B1;">Theoretical research</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">N.A.</td>
<td align="char" valign="top" char="&#x00B1;">N.A.</td>
<td align="char" valign="top" char="&#x00B1;">N.A.</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref3">Azzopardi et al., 2018</xref></td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">More than 1,000 queries</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;" rowspan="9">Technological</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref18">Gao and Shah, 2020</xref></td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">100 Queries, and 100 results for each query</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref19">Gezici et al., 2021</xref></td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">57 Query topics over two popular search engines</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">N. A.</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref22">Joachims et al., 2017</xref></td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">10 Query tasks, 56 participants</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref29">Muussesa et al., 2014</xref></td>
<td align="char" valign="top" char="&#x00B1;">Survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Longitudinal study of 398 samples</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">No</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref40">Schoenherr and White, 2014</xref></td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">More than 50,000 unique queries with 20,000&#x2009;~&#x2009;50,000 users</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref41">Schulthei&#x00DF; and Lewandowski, 2021</xref></td>
<td align="char" valign="top" char="&#x00B1;">Online survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">2012 Users</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
<td align="char" valign="top" char="&#x00B1;">No</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref46">Virginia et al., 2021</xref></td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
<td align="char" valign="top" char="&#x00B1;">1,386 Product data with 5 judges to label the data</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
<td align="char" valign="top" char="&#x00B1;">N.A.</td>
<td align="char" valign="top" char="&#x00B1;">No</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Moderate</td>
</tr>
<tr>
<td align="left" valign="top" char="."><xref ref-type="bibr" rid="ref50">White and Horvitz, 2013</xref></td>
<td align="char" valign="top" char="&#x00B1;">Data-driven</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">8,732 Individuals number of queries 515 individuals to take a survey</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">Yes</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
<td align="char" valign="top" char="&#x00B1;">High</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p><italic>Research design is based on three-authors-agreed appropriateness of study design to the research objective. Quality of intervention is based on whether the proposed intervention is evaluated to fit long-term treatment. Generalizability is based on whether the research conclusion fits repeated examinations in other contexts</italic>.</p>
</table-wrap-foot>
</table-wrap>
<p>After reviewing all included articles, the authors compared and confirmed three perspectives for a holistic understanding of cyberchondria (<xref rid="fig2" ref-type="fig">Figure 2</xref>).</p>
<fig position="float" id="fig2">
<label>Figure 2</label>
<caption>
<p>Co-occurrence network diagram of paper keywords related to cyberchondria. Figure shows a core subgroup of 50 nodes, whereby nodes represent keywords of articles and edges represent the connection between two keywords that appear in the same article. Data sources are from 27 included articles, including 84 nodes and 197 undirected edges. The size of a node represents the weight of the edge. Gephi, a network graph software, was used to map the relationships between these keywords. As shown in this figure, existing studies examine cyberchondria under its associations with the ongoing COVID-19 emergency. Most studies focus on health anxiety pathology. The rest focuses on obsessive&#x2013;compulsive disorder, among which metacognition and intolerance of uncertainty are important concepts. This figure suggests research directions for the present study.</p>
</caption>
<graphic xlink:href="fpsyg-13-897426-g002.tif"/>
</fig>
</sec>
<sec id="sec14">
<title>Cognitive Perspective: Problematic Internet Use Driven by Metacognitions</title>
<p>Cognitive psychology literature links the obsessive and compulsive feature of cyberchondria when an individual&#x2019;s problematic Internet use is driven by metacognition of their health state. As a belief chain that precedes health anxiety, metacognition indicates that an individuals&#x2019; pre-thoughts about their health state will significantly impact their physical health, emotions, and obsessive and compulsive behaviors when coping with cyberchondria. Metacognition is proven to be associated with psychological disturbance and then with cyberchondria (<xref ref-type="bibr" rid="ref5">Bailey and Wells, 2015</xref>). Scholarship focus is on anxiety traits (<xref ref-type="bibr" rid="ref23">Jungmann and Witth&#x00F6;ft, 2020</xref>) and neuroticism (<xref ref-type="bibr" rid="ref35">Oniszczenko and Stanis&#x0142;awiak, 2019</xref>). Those with anxiety traits are more likely to adopt a threatening perspective to understand benign symptoms or external risks; this introduces fear and anxiety that may result in obsessive and compulsive OHIS (<xref ref-type="bibr" rid="ref34">Oniszczenko, 2021</xref>). Those with high intolerance of uncertainty (IU) tend to adopt a defensive pessimism (DP) strategy. This means that they usually think of all the things that could go wrong and then work diligently to prevent the perceived upcoming worst-case scenario (<xref ref-type="bibr" rid="ref31">Norem and Chang, 2002</xref>). The DP is directly linked with obsessive and compulsive OHIS; therefore, it is more likely to cause cyberchondria (<xref ref-type="bibr" rid="ref6">Bajcar and Babiak, 2020</xref>).</p>
<p>These studies echo different directions of metacognition proposed by <xref ref-type="bibr" rid="ref17">Fergus and Spada (2018)</xref>. Specifically, anxiety traits correspond to negative metacognition, i.e., &#x201C;Uncontrolled thinking about illness can cause illness.&#x201D; The condition develops into cyberchondria through mediation of anxiety and fear. The IU corresponds to positive metacognition that develops into cyberchondria through the mediation of self-protection, namely &#x201C;Worrying about illness better equips us to defend ourselves against illness.&#x201D; Others suggest that the effect of positive metacognition on cyberchondria is mediated by curiosity (<xref ref-type="bibr" rid="ref16">Fergus and Spada, 2017</xref>). Ultimately, scholars pay more attention to the effect of negative metacognition on cyberchondria as an OCD (<xref ref-type="bibr" rid="ref1">Airoldi et al., 2021</xref>; <xref ref-type="bibr" rid="ref53">Zheng et al., 2021</xref>).</p>
<p>The cognitive perspective associates cyberchondria with obsessive and compulsive OHIS driven by metacognitions. However, following the biopsychosocial approach of the OCD framework, individual information exposure and social interaction warrants further examination. This will be discussed in the next section.</p>
</sec>
<sec id="sec15">
<title>Social Perspective: The Contradiction Between Information Needs and Information Verification</title>
<p>Socially focused studies have typically linked cyberchondria with the escalating psychological distress led by the tension between an individual&#x2019;s reassurance-seeking needs and the uncertainty driven by unverified online information (<xref ref-type="bibr" rid="ref43">Starcevic et al., 2020a</xref>). Those with OCD are more likely to have excessive reassurance-seeking (ERS); they rely on the Internet because seeking interpersonal reassurance may cause them shame and fear (<xref ref-type="bibr" rid="ref36">Parsons and Alden, 2022</xref>). This trend has been amplified due to the health risks posed by COVID-19, especially since lockdowns and normalized social distancing have resulted in more Internet use to find information, socialize and fulfill emotional needs (<xref ref-type="bibr" rid="ref11">Cinelli et al., 2020</xref>; <xref ref-type="bibr" rid="ref39">Rovetta and Bhagavathula, 2020</xref>). However, this online information may not suffice, since OCD individuals need definitive explanations and trustworthy information sources (<xref ref-type="bibr" rid="ref44">Starcevic et al., 2020b</xref>). Ironically, these internet users perceive their health as fragile and continue to search online, yet they cannot fully depend on the veracity of online information. Consequently, they continue searching and sharing, leading to cyberchondria (<xref ref-type="bibr" rid="ref9">Bora et al., 2018</xref>; <xref ref-type="bibr" rid="ref37">Patwary et al., 2021</xref>). Obsessive and compulsive OHIS positively correlates with an individual&#x2019;s dependence on online information, information overload (<xref ref-type="bibr" rid="ref49">White and Horvitz, 2009</xref>), uncertainty (<xref ref-type="bibr" rid="ref13">Del Vicario et al., 2016</xref>), and perceived vulnerability (<xref ref-type="bibr" rid="ref24">Laato et al., 2020</xref>). Therefore, cyberchondria occurs through the escalating psychological distress led by tension between information needs and the inability to verify information sources.</p>
<p>This perspective highlights the paradoxical interactions between humans and the Internet during health emergencies. Online sharing and communication have been proven to positively affect the recovery of individuals in crisis (<xref ref-type="bibr" rid="ref2">Allen et al., 2014</xref>). A widely adopted intercultural cyberchondria severity scale (CSS-12; <xref ref-type="bibr" rid="ref02">McElroy et al., 2019</xref>) highlights four indicators: coercion, suffering, excess, and seeking comfort. The last two reflect our social perspective. <xref ref-type="bibr" rid="ref25">Maftei and Holman (2020)</xref> confirm that positive emotional support has helped prevent cyberchondria among the elderly during the COVID-19 pandemic. Their study shows the necessity of linking excessive and repeated OHIS with an individual&#x2019;s need to seek reassurance.</p>
<p>Overall, individuals rely on online information but cannot verify it, resulting in exacerbation of cyberchondria. Yet, the social perspective often disregards technology as a powerful mediator of social significance; it should be viewed as an infrastructure for technological&#x2013;social integration and not as simply a single external tool. This fascinating irony offers direction for further exploration.</p>
</sec>
<sec id="sec16">
<title>Technological Perspective: The Linkage Between Cyberchondria and Biased Information Environment</title>
<p>Regardless of whether health anxiety or OHIS is the first to occur, the information found in search results leads to an individual&#x2019;s escalating anxiety (<xref ref-type="bibr" rid="ref42">Starcevic, 2017</xref>). Understanding this information environment is key to examining cyberchondria under an OCD framework and predicting further interventions. Technologically focused studies associate cyberchondria with a biased online information environment driven by Search Engine Result Pages (SERP) algorithms.</p>
<p>Since titles of SERP results affect the clicking of corresponding web page results (<xref ref-type="bibr" rid="ref50">White and Horvitz, 2013</xref>), users are more likely to view and click on titles containing potentially severe medical terms. Specifically, the introduction of certain words in search results might aggravate cyberchondria. Additionally, search engines automatically generate variants of query terms when composing SERP to improve performance, which in turn can develop into issues of luring clicks and reinforcing worries. However, based on such complex algorithms, SERP do not necessarily cover all topics related to query terms and may be biased toward specific views (<xref ref-type="bibr" rid="ref19">Gezici et al., 2021</xref>). Individuals sometimes perceive benign symptoms as serious diseases after viewing online content and may experience psychological distress (<xref ref-type="bibr" rid="ref40">Schoenherr and White, 2014</xref>).</p>
<p>Echoing the social perspective, users trust search engines but cannot fully evaluate the search results (<xref ref-type="bibr" rid="ref41">Schulthei&#x00DF; and Lewandowski, 2021</xref>); this makes them vulnerable. The more trusting users are more likely to rely on the system and click on SERP; they are also more likely to classify common benign symptoms as serious diseases. Meanwhile, indulgence in SERP can be regarded as a form of compulsive internet use that lowers wellbeing by predicting increases in depression and stress over time; the resulting decrease in happiness may affect health (<xref ref-type="bibr" rid="ref29">Muussesa et al., 2014</xref>).</p>
<p>Thus, the manipulation of users&#x2019; obsessions with and trust of search engines forms a biased information environment. Users&#x2019; anxiety levels may increase after escalating compulsive online searching for reassurance&#x2014;potentially cultivating cyberchondria.</p>
</sec>
</sec>
<sec id="sec17">
<title>Discussion and Conclusion</title>
<sec id="sec18">
<title>Principal Findings</title>
<p>This article summarizes, contrasts, and confirms cognitive, social, and technological mediation perspectives to understand cyberchondria holistically. Specifically, the cognitive perspective links cyberchondria with obsessive and compulsive OHIS driven by metacognitions. The social perspective associates cyberchondria with escalating distress caused by the tension between ERS needs and information verification. The technology perspective highlights how manipulated algorithm-driven search engines shape biased information environments and affect cyberchondria. Results also pinpoint potential connections between the perspectives that are listed below.</p>
</sec>
<sec id="sec19">
<title>Discussion and Future Directions</title>
<p>An individual&#x2019;s metacognition is not isolated from others with broader social backgrounds. There is rich scholarship on social factors behind one&#x2019;s beliefs and thoughts, such as escape from social pressures (<xref ref-type="bibr" rid="ref45">Turkle, 1995</xref>) and gender differences (<xref ref-type="bibr" rid="ref24">Laato et al., 2020</xref>). Individual cognition should be linked to the social dynamics that underpin searches; this linkage might also be the key to solving the recursive relationship between health-related anxiety and cyberchondria. Irrespective of whether cyberchondria causes or is a result of health-related anxiety, the group characteristics and use patterns of an individual cannot be ignored. As highlighted by <xref ref-type="bibr" rid="ref14">Fergus and Dolan (2014)</xref>, cyberchondria in teenagers often manifests as addictions to online gaming and pornography. Their findings show how the cognitive and social perspectives are continually engaged. More research is anticipated on the interconnected relationships between the obsessive and compulsive feature of cyberchondria and other social-related disorders, such as social anxiety and online gaming disorder.</p>
<p>Furthermore, since modern social support systems are increasingly mediated online by socially mobile technologies, social and technological perspectives are inseparable. Although most studies treat search behaviors as central to the study of cyberchondria, we go further by recognizing that search results are driven by manipulated algorithms. Special attention is given to algorithm completions. In addition, certain groups are in particular need of online social support at different physiological stages of life and are more likely to suffer from OCD. Their experiences of cyberchondria may not all be accurately traced through quantitative log collection. Therefore, the qualitative study of the cyberchondria-related experiences of groups such as pregnant women and elderly patients also merits further discussion.</p>
<p>Finally, the influence of algorithm-driven search engines cannot be fully understood in the absence of users&#x2019; reactions. Therefore, the technology perspective has shown how the algorithm and intelligent search technology increasingly comprise what <xref ref-type="bibr" rid="ref38">Peters (2015</xref>, p. 37) called the infrastructure of social interaction. Echoing this prediction, some studies have explored how self-diagnosis is influenced by people sharing symptoms in online health-topic communities (<xref ref-type="bibr" rid="ref48">Wheatley et al., 2003</xref>; <xref ref-type="bibr" rid="ref20">Giles and Newbold, 2013</xref>); others have exhorted doctors to give patients more authoritative sources of information (<xref ref-type="bibr" rid="ref12">Conell et al., 2016</xref>) or to deliver mediations such as internet cognitive behavioral therapy (<xref ref-type="bibr" rid="ref30">Newby and McElroy, 2020</xref>). Therefore, further research is required on the relationship between cyberchondria, online source verification, and social trust. For instance, how could the standard of SERP be established with fair and verified results to alleviate concerns related to obsessive and compulsive viewing for health-related queries? Would the presence of more doctors in online communities improve the quality of shared information, thereby reducing cyberchondria? Such questions are worthy of further examination.</p>
</sec>
<sec id="sec20">
<title>Contribution and Limitation</title>
<p>The contributions of this study are three-fold. Theoretically, it proposes a more holistic view engaging cognitive, social, and technological perspectives, paving the way for a systematic framework to understand cyberchondria under the OCD framework wherein the three dimensions are interconnected. Clinically, it calls for chain-screening cyberchondria, obsessive and compulsive disorder, and other maladaptive social anxiety symptoms such as social anxiety and depression, as well as more professional psychoeducation. Socially, it appeals for more social support for risk-sensitive groups with high OCD potential, especially given the anxieties and panic caused by pandemics such as COVID-19 and the need to cope with long-distance socialization and quarantines. It also calls for a more just information environment. Specifically, when using algorithm-driven search engine technology to deliver health-related information, digital platforms should focus on the real distribution of the illness instead of simply pursuing potential patients&#x2019; click rates.</p>
<p>Concerning limitations, this study defends a holistic view rather than a single diagnostic view of understanding cyberchondria. Therefore, the authors may omit some papers during literature screening, especially those papers discussing the social dynamics behind symptoms.</p>
</sec>
<sec id="sec21">
<title>Conclusion</title>
<p>This targeted review, based on 27 peer-reviewed published articles from five authoritative databases, investigates cyberchondria to understand and assess treatment for the obsessive and compulsive symptoms of the condition from cognitive, social, and technological perspectives. The authors compare and confirm three forecasts to predict cyberchondria, stating that it is associated with an individual&#x2019;s metacognition, the tension between seeking reassurance from information and uncertainty caused by unverified online information, and algorithm-driven intelligent search engine technologies. These three perspectives are continually and dynamically engaged, despite their different foci, and theoretically and practically contribute to the current human knowledge on cyberchondria. Future research may explore areas such as the association between cyberchondria and other social-related psychological disorders, how cyberchondria correlates with social trust mediated by algorithm-driven search engines, and how medical professionals might provide OCD patients with reassurance and information verification&#x2014;thus decreasing the incidence of cyberchondria.</p>
</sec>
</sec>
<sec id="sec22">
<title>Author Contributions</title>
<p>YY and NT contributed to the conception and design of the study. ZL organized the statistical analysis. YY, NT, and ZL wrote the first draft of the manuscript. All authors worked on revisions of the manuscript, performed the additional analysis, wrote the sections of the manuscript, contributed to manuscript revision, read the manuscript, and approved the submitted version.</p>
</sec>
<sec id="sec23" sec-type="funding-information">
<title>Funding</title>
<p>This study was supported by the 2022 New Teaching Staff Scientific Research Initiative Plan of Beijing International Studies University (KYQH22A008) and the Chinese National Social Science Foundation (21BXW061).</p>
</sec>
<sec id="conf1" sec-type="COI-statement">
<title>Conflict of Interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="sec25" sec-type="disclaimer">
<title>Publisher&#x2019;s Note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
</body>
<back>
<ref-list>
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</ref-list>
<fn-group>
<fn id="fn0005">
<p><sup>1</sup>The authors refer to <xref ref-type="bibr" rid="ref21">Huelin et al. (2015)</xref> to define a non-systematic targeted review.</p>
</fn>
<fn id="fn0006">
<p><sup>2</sup>To improve the comprehensiveness of the literature screening of the third perspective, authors combined the term &#x201C;search engine&#x201D; with the original search term &#x201C;cyberchondria.&#x201D;</p>
</fn>
<fn id="fn0007">
<p><sup>3</sup>The citation number is not applicable to those articles published in and after the year of 2021.</p>
</fn>
</fn-group>
</back>
</article>