<?xml version="1.0" encoding="UTF-8" standalone="no"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.3 20070202//EN" "journalpublishing.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Psychol.</journal-id>
<journal-title>Frontiers in Psychology</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Psychol.</abbrev-journal-title>
<issn pub-type="epub">1664-1078</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpsyg.2017.02003</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Psychology</subject>
<subj-group>
<subject>Original Research</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Loneliness, Resilience, Mental Health, and Quality of Life in Old Age: A Structural Equation Model</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name><surname>Gerino</surname> <given-names>Eva</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/360930/overview"/>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name><surname>Roll&#x000E8;</surname> <given-names>Luca</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="author-notes" rid="fn001"><sup>&#x0002A;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/238465/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Sechi</surname> <given-names>Cristina</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/343322/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Brustia</surname> <given-names>Piera</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/355517/overview"/>
</contrib>
</contrib-group>
<aff id="aff1"><sup>1</sup><institution>Department of Psychology, University of Turin</institution>, <addr-line>Turin</addr-line>, <country>Italy</country></aff>
<aff id="aff2"><sup>2</sup><institution>Department of Pedagogy, Psychology, Philosophy, University of Cagliari</institution>, <addr-line>Cagliari</addr-line>, <country>Italy</country></aff>
<author-notes>
<fn fn-type="edited-by"><p>Edited by: Alberto Di Domenico, Universit&#x000E0; degli Studi &#x0201C;G. d&#x00027;Annunzio&#x0201D; Chieti&#x02014;Pescara, Italy</p></fn>
<fn fn-type="edited-by"><p>Reviewed by: Shulamit Ramon, University of Hertfordshire, United Kingdom; Paola Miano, Universit&#x000E0; degli Studi di Palermo, Italy</p></fn>
<fn fn-type="corresp" id="fn001"><p>&#x0002A;Correspondence: Luca Roll&#x000E8; <email>l.rolle&#x00040;unito.it</email></p></fn>
<fn fn-type="other" id="fn002"><p>This article was submitted to Emotion Science, a section of the journal Frontiers in Psychology</p></fn></author-notes>
<pub-date pub-type="epub">
<day>14</day>
<month>11</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="collection">
<year>2017</year>
</pub-date>
<volume>8</volume>
<elocation-id>2003</elocation-id>
<history>
<date date-type="received">
<day>13</day>
<month>09</month>
<year>2017</year>
</date>
<date date-type="accepted">
<day>01</day>
<month>11</month>
<year>2017</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x000A9; 2017 Gerino, Roll&#x000E8;, Sechi and Brustia.</copyright-statement>
<copyright-year>2017</copyright-year>
<copyright-holder>Gerino, Roll&#x000E8;, Sechi and Brustia</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<abstract><p><bold>Objectives:</bold> In the scientific literature on aging, a recent core issue has been the role of individuals&#x00027; internal and external resources, which are considered intrinsically connected, in contributing synergistically to physical and psychological quality of life (QoL). The current study investigates the way in which psychological factors&#x02014;such as, loneliness, resilience, and mental states, in terms of depression and anxiety symptoms&#x02014;affect the perceived QoL among elderly individuals.</p>
<p><bold>Method:</bold> Data from 290 elderly Italian participants were used to study the mediation effects of both mental health and resilience to elucidate the relationship between loneliness and psychophysical QoL.</p>
<p><bold>Results:</bold> The best model we obtained supports the mediation effect of both resilience and mental health between loneliness and mental and physical QoL. These results highlight that loneliness influences mental and physical QoL via two pathways, with the impact of loneliness mediated by mental health and resilience dimensions.</p>
<p><bold>Conclusions:</bold> The findings suggest the importance of the support that elderly people receive from social relationships. In terms of clinical interventions, the reduction of loneliness could be an important factor in primary prevention or the recovery process. A way to reduce levels of mental distress could be represented by the increasing of resilience and self-efficacy and reduction of loneliness dissatisfaction. A high degree of resiliency contributes to increasing perceived life quality at the physical and psychological levels, and at the same time, reducing anxiety and depressive symptoms.</p></abstract>
<kwd-group>
<kwd>old age</kwd>
<kwd>loneliness</kwd>
<kwd>resilience</kwd>
<kwd>mental health</kwd>
<kwd>quality of life</kwd>
</kwd-group>
<contract-sponsor id="cn001">Fondazione CRT<named-content content-type="fundref-id">10.13039/100007364</named-content></contract-sponsor>
<counts>
<fig-count count="2"/>
<table-count count="3"/>
<equation-count count="0"/>
<ref-count count="124"/>
<page-count count="12"/>
<word-count count="9709"/>
</counts>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="s1">
<title>Introduction</title>
<p>In old age, people experience profound changes and face important challenges, including modifications in their roles, retirement, and the death of loved ones (friends and family members). These experiences can increase their levels of stress and lead to a decrease in the resources that individuals feel they have in dealing with their daily lives (Sachs-Ericsson et al., <xref ref-type="bibr" rid="B101">2014</xref>).</p>
<p>In demographic studies, it has been estimated that by 2050, the elderly population in Europe will reach 28%, which emphasizes that the highest proportion of elderly people is currently concentrated on the European continent (B&#x000F6;rsch-Supan et al., <xref ref-type="bibr" rid="B22">2005</xref>). This percentage will rise to 34% in Italy by 2025 (United Nations, <xref ref-type="bibr" rid="B114">2002</xref>), while in the last Eurostat report (Eurostat, <xref ref-type="bibr" rid="B45">2015a</xref>), as of 1 January 2014, there were almost 94 million people aged 65 and over in the European Union. The report showed that 16.1% of these people were aged 65&#x02013;84 years, while 2.4% were 85 years and over. In this scenario, the health condition of the elderly is a core issue; however, although there is a shared recognition of the importance of this aspect at the medical, public, and social levels, unfortunately, it is often a neglected area of scientific study and intervention (National Board of Health and Welfare, Sweden, <xref ref-type="bibr" rid="B89">2008</xref>; Djukanovic et al., <xref ref-type="bibr" rid="B43">2015</xref>; Eurostat, <xref ref-type="bibr" rid="B46">2015b</xref>). As the issues of health, and above all, illness or disability in old age, are a matter of increasing public concern, a perspective on healthy aging is crucial when it comes to identifying, designing, and implementing appropriate strategies to meet the growing needs of the population (Djukanovic et al., <xref ref-type="bibr" rid="B43">2015</xref>).</p>
<p>Considering the projections on the European population aging&#x02014;especially in Italy&#x02014;it can be assumed that this issue will become increasingly central in national policies. Lately, as noted by Stephens et al. (<xref ref-type="bibr" rid="B110">2015</xref>), the focus of social policies has been changing, shifting from care or symptom reduction to the promotion of well-being according to the biopsychosocial paradigm. The Health Psychology perspective, in opposition to a deficit model, is useful for critically analyzing the effects of strategies to promote healthy aging and reflect on the factors that could improve their efficacy to develop more inclusive models of intervention. Old age is stereotypically considered a period of progressive decline, and consequently, a heavier and heavier healthcare burden for society. This bias in social narratives on aging is traditionally widespread (Jeste et al., <xref ref-type="bibr" rid="B73">2013</xref>; Settersten and Godlewski, <xref ref-type="bibr" rid="B104">2016</xref>), although it has been refuted by experts. For these reasons, and starting from a holistic perspective, there is a growing need for empirical studies that enable the assessment of psychological functioning and overall health in the Third Age (Fry and Debats, <xref ref-type="bibr" rid="B56">2010</xref>; Jeste et al., <xref ref-type="bibr" rid="B73">2013</xref>). Specifically, analyzing the scientific literature, it appears that little is known about the resources that contribute to resilience and well-being in the elderly, as the research has focused more on the weaknesses or dysfunctions in elderly people than on their strengths (Fry and Debats, <xref ref-type="bibr" rid="B56">2010</xref>).</p>
<p>According to the World Health Organization (<xref ref-type="bibr" rid="B123">2002</xref>, <xref ref-type="bibr" rid="B124">2015</xref>), quality of life (QoL) can be defined as a subjective perception of the self-positioning in life that combines a person&#x00027;s psychological and PHY&#x02014;cultural position, value system, expectations, aims and states, independence, and personal beliefs&#x02014;with the capacity to create relationships. From another viewpoint, the perspective assumed in the theoretical framework of health-related QoL is based on a complex set of relationships that involves biopsychosocial factors related to well-being (Bowling, <xref ref-type="bibr" rid="B23">2001</xref>; Ekwall et al., <xref ref-type="bibr" rid="B44">2005</xref>; Gerino et al., <xref ref-type="bibr" rid="B60">2015</xref>). In line with this, QoL is defined as a multidimensional concept with both objective and subjective factors that refer to general satisfaction with life or its components (Lawton, <xref ref-type="bibr" rid="B78">1991</xref>; Bowling et al., <xref ref-type="bibr" rid="B24">2002</xref>; Arkar et al., <xref ref-type="bibr" rid="B5">2004</xref>). In the context of geriatric psychology and older people&#x00027;s awareness, it is increasingly clear that individuals&#x00027; internal and external resources are intrinsically connected, and both these aspects contribute synergistically to physical and their psychological well-being (Ryff and Singer, <xref ref-type="bibr" rid="B100">2000</xref>; Fern&#x000E1;ndez-Ballesteros, <xref ref-type="bibr" rid="B47">2003</xref>, <xref ref-type="bibr" rid="B48">2008</xref>; Fry and Debats, <xref ref-type="bibr" rid="B56">2010</xref>).</p>
<sec>
<title>Loneliness, mental health, and quality of life</title>
<p>For the analysis of psychological factors that expose the elderly to the risk of malaise, it has been evidenced that depressive symptoms affect the QoL of the elderly population (Beekman et al., <xref ref-type="bibr" rid="B16">1999</xref>; Blane et al., <xref ref-type="bibr" rid="B19">2008</xref>). Concerning adult life, according to Blazer (<xref ref-type="bibr" rid="B20">2003</xref>), among the causes of emotional distress, the presence of depressive symptoms is the most frequent, as this condition significantly contributes to decreasing the QoL of the older segment of the population. For example, depressive symptoms have been proven to be associated with functional impairment, chronic diseases, and mortality (Schoevers et al., <xref ref-type="bibr" rid="B102">2000</xref>; Nilsson et al., <xref ref-type="bibr" rid="B90">2011</xref>; Djukanovic et al., <xref ref-type="bibr" rid="B43">2015</xref>). Moreover, researchers have identified close associations between the presence of depressive symptoms and loneliness (Barg et al., <xref ref-type="bibr" rid="B14">2006</xref>; Cacioppo et al., <xref ref-type="bibr" rid="B33">2006</xref>, <xref ref-type="bibr" rid="B32">2010</xref>; Hawkley et al., <xref ref-type="bibr" rid="B66">2009</xref>; Hawkley and Cacioppo, <xref ref-type="bibr" rid="B65">2010</xref>). As indicated by Peplau and Perlman (<xref ref-type="bibr" rid="B93">1982</xref>), loneliness can be defined as a set of negative emotional states arising when a subject feels a discrepancy, in an unfavorable direction, between the desired and actual social relationships. Studies have shown that loneliness can be a significant predictor of increases in depressive symptomatology at least 1 year later (Cacioppo et al., <xref ref-type="bibr" rid="B32">2010</xref>).</p>
<p>Although many older people maintain a satisfactory condition of life, risks related to loneliness and psychological distress grow with age (Fry and Debats, <xref ref-type="bibr" rid="B54">2002</xref>). As stated by Fry and Debats (<xref ref-type="bibr" rid="B54">2002</xref>), in fact, some elderly people with self-expectancies or internalized beliefs about their aging can experience severe anxiety connected with feelings of loneliness. Clinicians and institutions that are dealing with the elderly have shown a growing concern about its consequences, including profound depressive feelings. Cacioppo et al. (<xref ref-type="bibr" rid="B33">2006</xref>) observed that loneliness is associated with strong negative feelings, and other researchers have shown that it impairs self-regulation (Baumeister et al., <xref ref-type="bibr" rid="B15">2005</xref>) or that &#x0201C;[l]onely adults have poor emotion regulation and are less likely to use positive feelings to alleviate their negative mood&#x0201D; (Wong et al., <xref ref-type="bibr" rid="B121">2016</xref>, p. 2487). Loneliness, anxiety, and depressive symptoms may contribute synergistically to a significant decrease in levels of well-being (Liu and Guo, <xref ref-type="bibr" rid="B81">2007</xref>). In addition, Sachs-Ericsson et al. (<xref ref-type="bibr" rid="B101">2014</xref>) studied the consequences of rape in an elderly sample, and found a connection between loneliness, depression, anxiety, and psychological functioning. Considering that multiple studies have pointed out that depression and loneliness are strongly associated and that they have detrimental effects on well-being in the Third Age (Tiikkainen and Heikkinen, <xref ref-type="bibr" rid="B113">2005</xref>; Cacioppo et al., <xref ref-type="bibr" rid="B33">2006</xref>; Golden et al., <xref ref-type="bibr" rid="B61">2009</xref>; Theeke, <xref ref-type="bibr" rid="B111">2010</xref>, <xref ref-type="bibr" rid="B112">2012</xref>; Prieto-Flores et al., <xref ref-type="bibr" rid="B95">2011</xref>; LeRoy et al., <xref ref-type="bibr" rid="B80">2017</xref>), it is important to further investigate the prognosis for older persons suffering from depression (Bj&#x000F8;rkl&#x000F8;f et al., <xref ref-type="bibr" rid="B18">2013</xref>).</p>
</sec>
<sec>
<title>Loneliness, resilience, and QoL</title>
<p>In the general population, people with a low sense of self-efficacy are subject to an increased risk of physical and mental health issues (Marshall, <xref ref-type="bibr" rid="B86">1991</xref>; Krause, <xref ref-type="bibr" rid="B75">1994</xref>; Smith-Osborne and Felderhoff, <xref ref-type="bibr" rid="B109">2016</xref>). In the elderly, loneliness dissatisfaction can significantly contribute to reduce self-evaluations of perceived self-efficacy (i.e., Fry and Debats, <xref ref-type="bibr" rid="B54">2002</xref>). In Bandura&#x00027;s (<xref ref-type="bibr" rid="B6">1977</xref>) definition, self-efficacy can be conceptualized as the perception that a person has his/her own ability to enact effective and functional responses to environmental demands. Specifically, this construct refers to people&#x00027;s individual differences in their aptitudes and dispositions when they evaluate themselves as able or unable to cope with situational demands in different contexts and situations (Jerusalem and Schwarzer, <xref ref-type="bibr" rid="B72">1992</xref>). It can be considered a global personality trait, specifically, and permanently connected to the self-perception of mastery (Bandura, <xref ref-type="bibr" rid="B6">1977</xref>, <xref ref-type="bibr" rid="B7">1982</xref>, <xref ref-type="bibr" rid="B8">1986</xref>, <xref ref-type="bibr" rid="B11">1997</xref>, <xref ref-type="bibr" rid="B12">2000</xref>; Luszczynska et al., <xref ref-type="bibr" rid="B84">2005</xref>), and because of its core role in individuals&#x00027; evaluation of their skills, it is closely linked with the dimension of subjective well-being (Gabriel and Bowling, <xref ref-type="bibr" rid="B58">2004</xref>).</p>
<p>The level of generalized self-esteem is a factor that is interrelated with the dimension of well-being in its physical, emotional, and psychological components (Smith et al., <xref ref-type="bibr" rid="B107">2000</xref>; Bandura, <xref ref-type="bibr" rid="B13">2004</xref>; Fry and Debats, <xref ref-type="bibr" rid="B56">2010</xref>). Longitudinal studies support the view that resilience traits, like self-efficacy, are protective in the later life stage (Smith-Osborne and Felderhoff, <xref ref-type="bibr" rid="B109">2016</xref>) and that these beliefs are linked to stress resistance in the face of minor distress (i.e., anxiety and loneliness; e.g., Fry, <xref ref-type="bibr" rid="B53">2001</xref>; Fry and Debats, <xref ref-type="bibr" rid="B55">2006</xref>, <xref ref-type="bibr" rid="B56">2010</xref>). As pointed out by the American Psychological Association (<xref ref-type="bibr" rid="B2">2004</xref>) and Bonanno (<xref ref-type="bibr" rid="B21">2004</xref>), resilience is configured as a common response to losses and conditions of severe stress during the lifecycle. Concerning people&#x00027;s ability to deal with adverse conditions in the lifespan, the attention to the construct of resilience progressively increases in relation to QoL in older people (Fry and Keyes, <xref ref-type="bibr" rid="B57">2010</xref>; MacLeod et al., <xref ref-type="bibr" rid="B85">2016</xref>). Gattuso (<xref ref-type="bibr" rid="B59">2003</xref>), Braudy Harris (<xref ref-type="bibr" rid="B26">2008</xref>), and recently, other authors (Wiles et al., <xref ref-type="bibr" rid="B120">2012</xref>; Stephens et al., <xref ref-type="bibr" rid="B110">2015</xref>), have suggested that the construct of resilience is useful for understanding health in older people. The American Psychological Association (<xref ref-type="bibr" rid="B3">2011</xref>) defines resilience as a successful adaptation process in response to threatening, stressful, or traumatic adverse experiences, or the ability to bounce back from difficult life conditions. It is a flourishing state despite adversity (Hildon et al., <xref ref-type="bibr" rid="B67">2010</xref>), where, in the case of the elderly, &#x0201C;adversity&#x0201D; may be considered in terms of an increased frequency of life conditions that entail personal loss, inequalities, disabilities, and the general PHY challenges of aging (Stephens et al., <xref ref-type="bibr" rid="B110">2015</xref>).</p>
<p>Wild et al. (<xref ref-type="bibr" rid="B119">2013</xref>) stated that resilience is a key component in successful aging. Several authors have specified that the different generations do not differ in their ability to be resilient (Carstensen et al., <xref ref-type="bibr" rid="B34">2003</xref>; Laditka et al., <xref ref-type="bibr" rid="B76">2009</xref>; Vahia et al., <xref ref-type="bibr" rid="B115">2012</xref>), but MacLeod et al. (<xref ref-type="bibr" rid="B85">2016</xref>) stated that resilience may support longevity. Furthermore, according to these authors, high resilience in later life has been associated with positive health outcomes. According to the international scientific literature, it is possible to identify the following outcomes: reduced vulnerability to depressive symptomatology and mortality risks (Sharpley and Yardley, <xref ref-type="bibr" rid="B105">1999</xref>; Carstensen et al., <xref ref-type="bibr" rid="B34">2003</xref>; de Jager et al., <xref ref-type="bibr" rid="B40">2003</xref>; Fredrickson et al., <xref ref-type="bibr" rid="B52">2003</xref>; Inui, <xref ref-type="bibr" rid="B70">2003</xref>; Wallace, <xref ref-type="bibr" rid="B118">2003</xref>; Charney, <xref ref-type="bibr" rid="B36">2004</xref>; DeSalvo et al., <xref ref-type="bibr" rid="B41">2006</xref>; Montross et al., <xref ref-type="bibr" rid="B88">2006</xref>; Reichstadt et al., <xref ref-type="bibr" rid="B97">2007</xref>; Laditka et al., <xref ref-type="bibr" rid="B76">2009</xref>; Lamond et al., <xref ref-type="bibr" rid="B77">2009</xref>); better self-perceptions of aging successfully (Montross et al., <xref ref-type="bibr" rid="B88">2006</xref>); and increased levels of QoL, mental health, and well-being, with improved lifestyle behaviors (Inui, <xref ref-type="bibr" rid="B70">2003</xref>; Montross et al., <xref ref-type="bibr" rid="B88">2006</xref>; Reichstadt et al., <xref ref-type="bibr" rid="B97">2007</xref>; Vahia et al., <xref ref-type="bibr" rid="B115">2012</xref>). According to Connor and Zhang (<xref ref-type="bibr" rid="B38">2006</xref>), resilience is a key target of anxiety and depression treatment. Studying the role of the ability to savor positive life experiences in terms of older people&#x00027;s life satisfaction, Smith and Hollinger-Smith (<xref ref-type="bibr" rid="B108">2015</xref>) confirmed that people with lower levels of resilience tend to report higher depression. Finally, resilience seems to be a protective factor for depression symptoms in the case of the spousal careers of people with dementia (O&#x00027;Rourke et al., <xref ref-type="bibr" rid="B92">2010</xref>; O&#x00027;Dwyer et al., <xref ref-type="bibr" rid="B91">2013</xref>).</p>
<p>To our knowledge, and according to Bowling et al. (<xref ref-type="bibr" rid="B24">2002</xref>), the way in which psychological factors&#x02014;including loneliness, resilience, and individuals&#x00027; mental states, in terms of depression and anxiety&#x02014;affect the perceived QoL is still largely unexplored. As described above, authors have studied the psychological variables that can be predictive of QoL, but how variables mediate and influence perceived QoL requires further elucidation.</p>
</sec>
</sec>
<sec id="s2">
<title>Aims</title>
<p>The purpose of the study was to explore a multidimensional model including the relationships among loneliness, resilience, mental health, and mental and physical QoL among elderly individuals. In line with authors who found relationships between loneliness and mental and physical QoL (Tiikkainen and Heikkinen, <xref ref-type="bibr" rid="B113">2005</xref>; Cacioppo et al., <xref ref-type="bibr" rid="B33">2006</xref>; Golden et al., <xref ref-type="bibr" rid="B61">2009</xref>; Theeke, <xref ref-type="bibr" rid="B111">2010</xref>; Prieto-Flores et al., <xref ref-type="bibr" rid="B95">2011</xref>) and those who found relationships among loneliness, resilience, and mental health (Fry and Debats, <xref ref-type="bibr" rid="B54">2002</xref>; Fry and Keyes, <xref ref-type="bibr" rid="B57">2010</xref>; Wild et al., <xref ref-type="bibr" rid="B119">2013</xref>; Sachs-Ericsson et al., <xref ref-type="bibr" rid="B101">2014</xref>), our hypothesis was that higher loneliness levels would be associated with low levels of mental health and resilience, and loneliness, resilience, and mental health would be associated with mental and physical QoL. It was also expected that both resilience and mental health would mediate the negative association between loneliness and mental/physical QoL.</p>
</sec>
<sec sec-type="materials and methods" id="s3">
<title>Materials and methods</title>
<sec>
<title>Participants</title>
<p>The sample comprised 290 older adults from Italy (70% females and 30% males), aged 65&#x02013;90 years (<italic>M</italic><sub><italic>Age</italic></sub> &#x0003D; 74.7 years, <italic>SD</italic> &#x0003D; 6.9 years); the participants were split into two groups&#x02014;those in the age range of 65&#x02013;74 years old (66% females and 34% males) comprised the young old group (<italic>M</italic><sub><italic>Age</italic></sub> &#x0003D; 69 years, <italic>SD</italic> &#x0003D; 2.9 years), while those older than 74 years (73% females and 27% males) comprised the old group (<italic>M</italic><sub><italic>Age</italic></sub> &#x0003D; 81 years, <italic>SD</italic> &#x0003D; 4.3 years). Participants volunteered for the study. They were all Italian native speakers, and they were active in the cultural and social activities of the neighborhood. None of the participants were undergoing medical/neurological or psychiatric treatment at the time of assessment. Their education levels were as follows: 58% of the participants had an elementary school education, 31% had a high school diploma, and 11% had completed a university degree. Fifty-one percent of participants were married or in a civil partnership and lived independently with their spouses; 49% of the participants were single, widowed, separated, or divorced and lived alone (40.2%), with their children (6.4%), with brothers or sisters (1.4%), or with other people (e.g., carers; 1%).</p>
</sec>
<sec>
<title>Measures</title>
<sec>
<title>The UCLA loneliness scale (version 3)</title>
<p>The UCLA Loneliness Scale (Version 3) (Russell, <xref ref-type="bibr" rid="B99">1996</xref>; 10 positively worded items [PI] &#x0003D; non-loneliness and 10 negatively worded items [NI] &#x0003D; loneliness) is used to assess participants&#x00027; level of loneliness, defined by an incongruity between actual and desired social interaction. On this scale, participants are asked to report how often (from 1 &#x0003D; never to 4 &#x0003D; often) they feel the way illustrated for each item. Positive items are reverse coded to generate a global measure in which higher scores denote greater loneliness. For the present study, the authors adapted the scale into Italian using the back-translation technique to guarantee the semantic correspondence of the Italian and English versions. Based on the current participants, the Cronbach&#x00027;s alpha coefficient was 0.87 for global loneliness, 0.83 for the loneliness subscale (NI), and 0.84 for the non-loneliness subscale (PI).</p>
</sec>
<sec>
<title>The geriatric anxiety inventory&#x02014;short form</title>
<p>The Geriatric Anxiety Inventory&#x02014;Short Form (GAI-SF; Byrne and Pachana, <xref ref-type="bibr" rid="B31">2011</xref>) consists of five items, and it is used as a screening tool for individualizing anxiety in older adults. Questions require yes/no answers. It was developed as a briefer version of the full 20-item GAI, and its validity and internal consistency have been demonstrated (Cronbach&#x00027;s alpha 0.81). For the present investigation, the authors adapted the GAI-SF into Italian using the back-translation technique to guarantee the semantic correspondence of the Italian and English versions. Based on the current participants, the Cronbach&#x00027;s alpha coefficient was 0.78.</p>
</sec>
<sec>
<title>The geriatric depression scale</title>
<p>The Geriatric Depression Scale&#x02014;Short Form (GDS-SF; Hoyl et al., <xref ref-type="bibr" rid="B68">1999</xref>; Italian version, Rinaldi et al., <xref ref-type="bibr" rid="B98">2003</xref>) consists of five items, and it is used as a screening tool for individualizing depression in older adults. It comprises items about how the person has felt over the past week. The questions require yes/no answers. It was developed to be a version of the 15-item GDS, and its overall performance has been demonstrated to be comparable to that of the 15-item scale. Moreover, the 5-item GDS is a better screening tool than the 15-item version is (Hoyl et al., <xref ref-type="bibr" rid="B68">1999</xref>). Based on the current participants, the internal consistency coefficient was 0.70.</p>
</sec>
<sec>
<title>The generalized self-efficacy scale</title>
<p>The Generalized Self-efficacy (GSE) Scale (Jerusalem and Schwarzer, <xref ref-type="bibr" rid="B71">1986</xref>; Italian version, Sibilia et al., <xref ref-type="bibr" rid="B106">1995</xref>) consists of 10 items, and it is designed to measure a sense of perceived self-efficacy with the objective of predicting coping with everyday adversity, as well as adjustment after experiencing different types of stressful life events. The participant responds to the instrument using a 4-point Likert scale (from 1 &#x0003D; not at all true to 4 &#x0003D; exactly true). A high score signifies a high perception of self-efficacy. The GSE has been administered widely and has been found to have satisfactory internal consistency reliability. Based on the current participants, the internal consistency coefficient was 0.87.</p>
</sec>
<sec>
<title>The resilience scale</title>
<p>The Resilience Scale (RS; Wagnild and Young, <xref ref-type="bibr" rid="B117">1993</xref>; Italian version Peveri, <xref ref-type="bibr" rid="B94">2010</xref>) consists of 10 items rated on a 7-point Likert scale (from 1 &#x0003D; disagree to 7 &#x0003D; agree), and it is a measure of the ability to bear stressful life events and make meaning from challenges. The concurrent validity and internal consistency reliability of the RS scale have been shown to be adequate (Wagnild, <xref ref-type="bibr" rid="B116">2009</xref>). Based on the current participants, the internal consistency coefficient was 0.91.</p>
</sec>
<sec>
<title>The world health organization quality of life questionnaire</title>
<p>The World Health Organization QoL (WHOQOL-BREF; World Health Organization, <xref ref-type="bibr" rid="B122">1993</xref>; Italian version, De Girolamo et al., <xref ref-type="bibr" rid="B39">2000</xref>) Questionnaire evaluates QoL in four areas, as follows: psychological health (PSY), physical health (PHY), environment (E), and social relationships (SR). It includes 24 self-report items, and the participant responds to the instrument via a 5-point Likert scale (from 1 &#x0003D; not at all to 5 &#x0003D; completely). It is a shorter version of the original tool, and it may be better adapted for use in big clinical trials or studies. Higher scores show a higher perceived QoL. The WHOQOL-BREF is appropriate for use with older adults (Lucas-Carrasco, <xref ref-type="bibr" rid="B83">2012</xref>). For this study, the subscales assessing QoL across the physical and PSY domains were used. Based on the current participants, the internal consistency coefficient was 0.85 for the PHY subscale and 0.78 for the PSY subscale.</p>
</sec>
</sec>
<sec>
<title>Procedure</title>
<p>All participants were contacted individually at their place of living and signed the written informed consent. Participants who agreed to participate, understood the instructions, and met the selection criteria autonomously completed a questionnaire on demographic data, the UCLA, GAI-SF, GDS-SF, GSE, RS, and WHOQOL&#x02013;BREF self-reports. The questionnaires were offered in a counterbalanced order on two forms, and no order effect was found. The confidentiality of participants&#x00027; answers was guaranteed. The time needed to fill in the questionnaires was approximately 60 min.</p>
</sec>
<sec>
<title>Data analyses</title>
<p>Descriptive statistics were computed on the evaluated psychological variables, reporting means, standard deviations, kurtosis, and skewness. The association between continuous variables was tested by means of Pearson correlations. A two-step process was adopted to test the hypothesized model, as follows: (1) a confirmatory factor analysis was implemented to create a measurement model with an adequate fit to the data; and (2) the structural equation model (SEM) established after this phase was verified in the second step (Anderson and Gerbing, <xref ref-type="bibr" rid="B4">1988</xref>). The hypothesized model comprised four latent factors (loneliness, mental health, resilience, and mental and physical QoL) and eight observed variables. Specifically, it comprised one hypothetical latent independent factor, two latent mediator factors (mental health and resilience), and one latent dependent factor (mental and physical QoL). The loneliness latent factor was measured using the two subscales of UCLA (PI and NI). The mental health latent factor was measured using two sources, the GAI-SF and GDS-SF, while the resilience latent variable was measured by the GSE and RS. As mentioned above, the concept of resilience is a multifaceted construct, and together, these scales may provide a more complete assessment of resilience than each measure alone would. Finally, the mental and physical QoL latent factor was measured using two subscales of the WHOQOL&#x02013;BREF (PHY and PSY).</p>
<p>For evaluating the model fit, a set of fit indices were used based on recommended criteria, including the following: a comparative fit index (CFI) and Tucker&#x02013;Lewis index (TLI) &#x02265;0.90, which showed an acceptable fit of the model (Bentler, <xref ref-type="bibr" rid="B17">1990</xref>; Schumacker and Lomax, <xref ref-type="bibr" rid="B103">1996</xref>; Kline, <xref ref-type="bibr" rid="B74">2005</xref>; Brown, <xref ref-type="bibr" rid="B27">2006</xref>); the root mean square error of approximation (RMSEA), where values &#x02264;0.05 can be regarded as an appropriate fit and values between 0.05 and 0.08 as an acceptable fit (Browne and Cudeck, <xref ref-type="bibr" rid="B28">1993</xref>; Hu and Bentler, <xref ref-type="bibr" rid="B69">1999</xref>; Brown, <xref ref-type="bibr" rid="B27">2006</xref>); and the standardized root mean square residual (SRMR) of &#x0003C;0.1 (Bentler, <xref ref-type="bibr" rid="B17">1990</xref>).</p>
<p>To compare the models, the Akaike information criterion (AIC; Akaike, <xref ref-type="bibr" rid="B1">1987</xref>) of smaller values representing a better fit of the hypothesized model (Byrne, <xref ref-type="bibr" rid="B30">2001</xref>) and expected cross-validation index (Browne and Cudeck, <xref ref-type="bibr" rid="B28">1993</xref>) of the smallest values exhibiting the greatest potential for replication (Byrne, <xref ref-type="bibr" rid="B30">2001</xref>) were also considered to establish the best model. Finally, to establish whether the hypothesized model performed equivalently across age, multi-group analyses were run.</p>
</sec>
</sec>
<sec sec-type="results" id="s4">
<title>Results</title>
<sec>
<title>Descriptive analysis</title>
<p>Descriptive statistics of eight observed variables were tested to check for the normality of distribution. For each of the observed variables, the kurtosis and skewness values were between 1 and &#x02212;1; therefore, this sample can be defined as having a normal distribution. The descriptive statistics of the eight observed variables are shown in Table <xref ref-type="table" rid="T1">1</xref>. Correlations were computed to study the relationships of all eight measured continuous variables. The coefficients of correlation are shown in Table <xref ref-type="table" rid="T2">2</xref>. The results revealed that loneliness is significantly and positively correlated with anxiety and depression and negatively associated with resilience, self-efficacy, and psychological and PHY.</p>
<table-wrap position="float" id="T1">
<label>Table 1</label>
<caption><p>Means, standard deviations, skews, and kurtosis for eight observed variables.</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th valign="top" align="left"><bold>Variable</bold></th>
<th valign="top" align="center"><bold>M</bold></th>
<th valign="top" align="center"><bold><italic>SD</italic></bold></th>
<th valign="top" align="center"><bold>Skewness</bold></th>
<th valign="top" align="center"><bold>Kurtosis</bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">PI</td>
<td valign="top" align="center">28.4</td>
<td valign="top" align="center">4.4</td>
<td valign="top" align="center">&#x02212;0.7</td>
<td valign="top" align="center">1</td>
</tr>
<tr>
<td valign="top" align="left">NI</td>
<td valign="top" align="center">24.6</td>
<td valign="top" align="center">6</td>
<td valign="top" align="center">0.3</td>
<td valign="top" align="center">0.1</td>
</tr>
<tr>
<td valign="top" align="left">GAI-SF</td>
<td valign="top" align="center">1.7</td>
<td valign="top" align="center">1.7</td>
<td valign="top" align="center">0.6</td>
<td valign="top" align="center">&#x02212;0.9</td>
</tr>
<tr>
<td valign="top" align="left">GDS-SF</td>
<td valign="top" align="center">1.2</td>
<td valign="top" align="center">1.2</td>
<td valign="top" align="center">1</td>
<td valign="top" align="center">0.8</td>
</tr>
<tr>
<td valign="top" align="left">RS</td>
<td valign="top" align="center">54.9</td>
<td valign="top" align="center">9</td>
<td valign="top" align="center">&#x02212;0.9</td>
<td valign="top" align="center">1</td>
</tr>
<tr>
<td valign="top" align="left">GSE</td>
<td valign="top" align="center">27.7</td>
<td valign="top" align="center">4.1</td>
<td valign="top" align="center">&#x02212;0.4</td>
<td valign="top" align="center">0.5</td>
</tr>
<tr>
<td valign="top" align="left">PSY</td>
<td valign="top" align="center">80.7</td>
<td valign="top" align="center">13.1</td>
<td valign="top" align="center">&#x02212;0.5</td>
<td valign="top" align="center">0.8</td>
</tr>
<tr>
<td valign="top" align="left">PHY</td>
<td valign="top" align="center">101.7</td>
<td valign="top" align="center">18</td>
<td valign="top" align="center">&#x02212;0.6</td>
<td valign="top" align="center">0.6</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p><italic>PI, positively worded items of UCLA Loneliness Scale-3; NI, negatively worded items negatively worded items; GAI-SF, Geriatric Anxiety Inventory&#x02014;short form; GDS-SF, Geriatric Depression Scale; RS, Resilience Scale; GSE, Generalized Self-Efficacy Scale; PSY, psychological health subscale of WHOQOL-BREF-World Health Organization Quality of Life Questionnaire; PHY, physical health subscale of WHOQOL-BREF- World Health Organization Quality of Life Questionnaire</italic>.</p>
</table-wrap-foot>
</table-wrap>
<table-wrap position="float" id="T2">
<label>Table 2</label>
<caption><p>Pearson correlations for the eight observed variables.</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th/>
<th valign="top" align="center"><bold>1</bold></th>
<th valign="top" align="center"><bold>2</bold></th>
<th valign="top" align="center"><bold>3</bold></th>
<th valign="top" align="center"><bold>4</bold></th>
<th valign="top" align="center"><bold>5</bold></th>
<th valign="top" align="center"><bold>6</bold></th>
<th valign="top" align="center"><bold>7</bold></th>
<th valign="top" align="center"><bold>8</bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">1.PI</td>
<td valign="top" align="center">1</td>
<td/>
<td/>
<td/>
<td/>
<td/>
<td/>
<td/>
</tr>
<tr>
<td valign="top" align="left">2.NI</td>
<td valign="top" align="center">0.403<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">1</td>
<td/>
<td/>
<td/>
<td/>
<td/>
<td/>
</tr>
<tr>
<td valign="top" align="left">3.GAI-SF</td>
<td valign="top" align="center">0.288<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.268<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">1</td>
<td/>
<td/>
<td/>
<td/>
<td/>
</tr>
<tr>
<td valign="top" align="left">4.GDS-SF</td>
<td valign="top" align="center">0.368<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.330<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.447<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">1</td>
<td/>
<td/>
<td/>
<td/>
</tr>
<tr>
<td valign="top" align="left">5.RS</td>
<td valign="top" align="center">&#x02212;0.394<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">&#x02212;0.422<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">&#x02212;0.388<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">&#x02212;0.498<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">1</td>
<td/>
<td/>
<td/>
</tr>
<tr>
<td valign="top" align="left">6.GSE</td>
<td valign="top" align="center">&#x02212;0.160<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">&#x02212;0.238<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">&#x02212;0.335<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">&#x02212;0.314<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.629<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">1</td>
<td/>
<td/>
</tr>
<tr>
<td valign="top" align="left">7.PSY</td>
<td valign="top" align="center">&#x02212;0.431<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">&#x02212;0.410<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">&#x02212;0.531<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">&#x02212;0.559<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.676<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.529<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">1</td>
<td/>
</tr>
<tr>
<td valign="top" align="left">8.PHY</td>
<td valign="top" align="center">&#x02212;0.289<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">&#x02212;0.302<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">&#x02212;0.387<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">&#x02212;0.439<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.509<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.410<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.638<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">1</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="TN1">
<label>&#x0002A;&#x0002A;</label>
<p><italic>p&#x0003C;0.01</italic>.</p></fn>
</table-wrap-foot>
</table-wrap>
</sec>
<sec>
<title>Mediation model</title>
<sec>
<title>First phase: measurement model</title>
<p>The confirmatory factor analysis measured four latent factors (loneliness, mental health, resilience, and mental and physical QoL) and eight observed variables (Figure <xref ref-type="fig" rid="F1">1</xref>). All latent factors were found to associate with one another. The model was assessed using the method of maximum likelihood. A test of the measurement model showed a very acceptable fit to the data, &#x003C7;<sup>2</sup> &#x0003D; 27.80, <italic>df</italic> &#x0003D; 14 <italic>p</italic> &#x0003D; 0.05, CFI &#x0003D; 0.99, TLI &#x0003D; 0.98, RMSEA &#x0003D; 0.05 [90% confidence interval (CI): 0.01&#x02013;0.08], SRMR &#x0003D; 0.03. In addition, all the factor loadings were significant, <italic>p</italic> &#x0003C; 0.001, which supports the convergent validity of the indicators (Anderson and Gerbing, <xref ref-type="bibr" rid="B4">1988</xref>). These results indicate that all the latent factors were well exemplified by their observed variables. In addition, the four latent factors were significantly connected, <italic>p</italic> &#x0003C; 0.001. Thus, this model was used to examine the hypothetical structural model.</p>
<fig id="F1" position="float">
<label>Figure 1</label>
<caption><p>The measurement model (<italic>N</italic> &#x0003D; 290). Factor loadings are standardized. PI, positively worded items of UCLA <italic>Loneliness Scale-3</italic>; NI, negatively worded items negatively worded items; GAI-SF, Geriatric <italic>Anxiety Inventory&#x02014;short form</italic>; GDS-SF, <italic>Geriatric Depression Scale;</italic> RS, <italic>Resilience Scale;</italic> GSE, <italic>Generalized Self-Efficacy Scale;</italic> PSY, psychological health subscale of <italic>WHOQOL-BREF- World Health Organization Quality of Life Questionnaire;</italic> PHY, <italic>physical</italic> health subscale of <italic>WHOQOL-BREF- World Health Organization Quality of Life Questionnaire</italic>. <sup>&#x0002A;</sup><italic>p</italic> &#x0003C; 0.001.</p></caption>
<graphic xlink:href="fpsyg-08-02003-g0001.tif"/>
</fig>
</sec>
<sec>
<title>Second phase: the structural equation model</title>
<p>The SEM was verified using the method of maximum likelihood. To obtain the best model, five alternative models were calculated (Table <xref ref-type="table" rid="T3">3</xref>). First, a partially mediated model (Model A) with two mediators and a direct path from loneliness to mental and physical QoL showed an appropriate fit, &#x003C7;<sup>2</sup> &#x0003D; 29.85, <italic>df</italic> &#x0003D; 15 <italic>p</italic> &#x0003D; 0.01, CFI &#x0003D; 0.98, TLI &#x0003D; 0.97, RMSEA &#x0003D; 0.06 (90% CI: 0.03&#x02013;0.08), SRMR &#x0003D; 0.04. However, it is important to note that there was no significant direct effect of loneliness mental and physical QoL in this model, <italic>b</italic> &#x0003D; 0.11 <italic>p</italic> &#x0003E; 0.05. Thus, a fully mediated model (Model B) was verified with this path constrained to zero, which showed a good fit to the data, &#x003C7;<sup>2</sup> &#x0003D; 29.97, <italic>df</italic> &#x0003D; 16 <italic>p</italic> &#x0003D; 0.02, CFI &#x0003D; 0.98, TLI &#x0003D; 0.97, RMSEA &#x0003D; 0.05 (90% CI:0.02&#x02013;0.08), SRMR &#x0003D; 0.03.</p>
<table-wrap position="float" id="T3">
<label>Table 3</label>
<caption><p>Fit indices among the competing models.</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th/>
<th valign="top" align="center"><bold>Model A</bold></th>
<th valign="top" align="center"><bold>Model B</bold></th>
<th valign="top" align="center"><bold>Model C</bold></th>
<th valign="top" align="center"><bold>Model D</bold></th>
<th valign="top" align="center"><bold>Model E<xref ref-type="table-fn" rid="TN2"><sup>&#x0002A;</sup></xref></bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">&#x003C7;<sup>2</sup></td>
<td valign="top" align="center">29.85</td>
<td valign="top" align="center">29.97</td>
<td valign="top" align="center">23.84</td>
<td valign="top" align="center">26.66</td>
<td valign="top" align="center">23.84</td>
</tr>
<tr>
<td valign="top" align="left"><italic>df</italic></td>
<td valign="top" align="center">15</td>
<td valign="top" align="center">16</td>
<td valign="top" align="center">15</td>
<td valign="top" align="center">16</td>
<td valign="top" align="center">15</td>
</tr>
<tr>
<td valign="top" align="left">CFI</td>
<td valign="top" align="center">0.98</td>
<td valign="top" align="center">0.98</td>
<td valign="top" align="center">0.99</td>
<td valign="top" align="center">0.99</td>
<td valign="top" align="center">0.99</td>
</tr>
<tr>
<td valign="top" align="left">TLI</td>
<td valign="top" align="center">0.97</td>
<td valign="top" align="center">0.97</td>
<td valign="top" align="center">0.98</td>
<td valign="top" align="center">0.98</td>
<td valign="top" align="center">0.98</td>
</tr>
<tr>
<td valign="top" align="left">RMSEA</td>
<td valign="top" align="center">0.06</td>
<td valign="top" align="center">0.05</td>
<td valign="top" align="center">0.05</td>
<td valign="top" align="center">0.05</td>
<td valign="top" align="center">0.05</td>
</tr>
<tr>
<td valign="top" align="left">CI for RMSEA</td>
<td valign="top" align="center">0.03&#x02013;0.08</td>
<td valign="top" align="center">0.02&#x02013;0.08</td>
<td valign="top" align="center">0.00&#x02013;0.08</td>
<td valign="top" align="center">0.01&#x02013;0.08</td>
<td valign="top" align="center">0.00&#x02013;0.08</td>
</tr>
<tr>
<td valign="top" align="left">SRMR</td>
<td valign="top" align="center">0.04</td>
<td valign="top" align="center">03</td>
<td valign="top" align="center">03</td>
<td valign="top" align="center">03</td>
<td valign="top" align="center">03</td>
</tr>
<tr>
<td valign="top" align="left">AIC</td>
<td valign="top" align="center">71.85</td>
<td valign="top" align="center">71.85</td>
<td valign="top" align="center">65.84</td>
<td valign="top" align="center">66.66</td>
<td valign="top" align="center">65.84</td>
</tr>
<tr>
<td valign="top" align="left">ECVI</td>
<td valign="top" align="center">0.25</td>
<td valign="top" align="center">0.25</td>
<td valign="top" align="center">0.23</td>
<td valign="top" align="center">0.23</td>
<td valign="top" align="center">0.23</td>
</tr>
<tr>
<td valign="top" align="left">CI for ECVI</td>
<td valign="top" align="center">0.21&#x02013;0.32</td>
<td valign="top" align="center">0.21&#x02013;0.32</td>
<td valign="top" align="center">0.20&#x02013;0.29</td>
<td valign="top" align="center">0.20&#x02013;0.29</td>
<td valign="top" align="center">0.20&#x02013;0.29</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p><italic>N &#x0003D; 290</italic>.</p>
<fn id="TN2">
<label>&#x0002A;</label>
<p><italic>Represents the best model</italic>.</p></fn>
<p><italic>CFI comparative fit index, TLI Tucker Lewis Index, RMSEA root-mean-square error of approximation, SRMR standardized root-mean square residual, AIC Akaike information criterion, ECVI expected cross validation index, CI confidence interval</italic>.</p>
</table-wrap-foot>
</table-wrap>
<p>Comparing the chi-square differences, no significant difference between Model A and Model B, &#x00394;&#x003C7;<sup>2</sup> &#x0003D; 0.12, <italic>df</italic> &#x0003D; 1, <italic>p</italic> &#x0003E; 0.05, showing that the Model B exhibited a better fit for the data. Next, a path from mental health to resilience was added to the fully mediated model (Model C), and the results showed an extremely satisfactory fit to the data, &#x003C7;<sup>2</sup> &#x0003D; 23.84, <italic>df</italic> &#x0003D; 15 <italic>p</italic> &#x0003D; 0.07, CFI &#x0003D; 0.99, TLI &#x0003D; 0.98, RMSEA &#x0003D; 0.05 (90% CI: 0.0&#x02013;0.08), SRMR &#x0003D; 0.03. Comparing Model B to Model C, &#x00394;&#x003C7;<sup>2</sup> &#x0003D; 6.13<italic>, df</italic> &#x0003D; 1, <italic>p</italic> &#x0003D; 0.01, it was shown that the added path contributed significantly to the model. The path coefficient from mental health to resilience was significant, <italic>b</italic> &#x0003D; &#x02212;0.51, <italic>p</italic> &#x0003C; 0.01; however, the path from loneliness to resilience became non-significant, <italic>b</italic> &#x0003D; &#x02212;0.28, <italic>p</italic> &#x0003E; 0.05. Thus, this path was eliminated, and the model was retested (Model D). The results also showed an extremely appropriate fit to the data, &#x003C7;<sup>2</sup> &#x0003D; 26.66, <italic>df</italic> &#x0003D; 16 <italic>p</italic> &#x0003D; 0.05, CFI &#x0003D; 0.99, TLI &#x0003D; 0.98, RMSEA &#x0003D; 0.05 (90% CI: 0.01&#x02013;0.08), SRMR &#x0003D; 0.03. However, the chi-square difference between Model C and Model D was not significant, &#x00394;&#x003C7;<sup>2</sup> &#x0003D; 2.82<italic>, df</italic> &#x0003D; 1, <italic>p</italic> &#x0003E; 0.05, suggesting that Model D was better.</p>
<p>Finally, Model E was verified by adding a path from resilience to mental health to Model B, which showed a good fit to the data, &#x003C7;<sup>2</sup> &#x0003D; 23.84, <italic>df</italic> &#x0003D; 15 <italic>p</italic> &#x0003D; 0.07, CFI &#x0003D; 0.99, TLI &#x0003D; 0.98, RMSEA &#x0003D; 0.05 (90% CI: 0.0&#x02013;0.08), SRMR &#x0003D; 0.03. The standardized path coefficients from resilience to mental health, <italic>b</italic> &#x0003D; &#x02212;0.40, <italic>p</italic> &#x0003C; 0.01, from loneliness to mental health, <italic>b</italic> &#x0003D; 0.49, <italic>p</italic> &#x0003C; 0.001, and from loneliness to resilience, <italic>b</italic> &#x0003D; &#x02212;0.66, <italic>p</italic> &#x0003C; 0.001, were significant.</p>
<p>The chi-square difference between Model D and Model E was not significant, &#x00394;&#x003C7;<sup>2</sup> &#x0003D; 2.82<italic>, df</italic> &#x0003D; 1, <italic>p</italic> &#x0003E; 0.05, implying that Model E was a better model. Furthermore, the slightly smaller AIC value (see Table <xref ref-type="table" rid="T3">3</xref>) implied that Model E was better than Model D. Therefore, Model E was designated as the best model (Figure <xref ref-type="fig" rid="F2">2</xref>). In Model E, mental health and resilience fully mediated the link between loneliness and mental and physical QoL. The partial mediation effect of mental health in the link between resilience and mental and physical QoL was significant. Moreover, resilience partially mediated the link between loneliness and mental health (z &#x0003D; &#x02212;2.98, <italic>p</italic> &#x0003C; 0.001). Especially, the path of loneliness &#x02192; resilience &#x02192; mental health &#x02192; mental, and physical QoL was significant. This path indicated that elderly people with high loneliness levels are not able to face the adversity, trauma, and stress, which may lower their mental health, and in turn, lead to low mental and physical QoL.</p>
<fig id="F2" position="float">
<label>Figure 2</label>
<caption><p>The finalized structural model (<italic>N</italic> &#x0003D; 290). PI, positively worded items of UCLA <italic>Loneliness Scale-3</italic>; NI, negatively worded items negatively worded items; GAI-SF, Geriatric <italic>Anxiety Inventory&#x02014;short form</italic>; GDS-SF, <italic>Geriatric Depression Scale;</italic> RS, <italic>Resilience Scale;</italic> GSE, <italic>Generalized Self-Efficacy Scale;</italic> PSY, psychological health subscale of <italic>WHOQOL-BREF&#x02013;World Health Organization Quality of Life Questionnaire;</italic> PHY, <italic>physical</italic> health subscale of <italic>WHOQOL-BREF-World Health Organization Quality of Life Questionnaire</italic>. <sup>&#x0002A;</sup><italic>p</italic> &#x0003C; 0.01 <sup>&#x0002A;&#x0002A;</sup><italic>p</italic> &#x0003C; 0.001.</p></caption>
<graphic xlink:href="fpsyg-08-02003-g0002.tif"/>
</fig>
<p>Finally, the multigroup analysis was tested to investigate whether the path coefficients were moderated by age. The age differences (young old group and old group) were tested by comparing the first model, which allows the structural paths to vary across ages, with the second model, which constrains the structural paths across ages to be equal. All the factor loadings, structure co-variances, and error variances were constrained to be equal.</p>
<p>The non-significant chi-square differences between the two models, &#x00394;&#x003C7;<sup>2</sup> &#x0003D; 8.43, <italic>df</italic> &#x0003D; 6, <italic>p</italic> &#x0003E; 0.05, as well as the slightly smaller AIC value, suggested that the structural paths of the final model did not differ by age, offering initial support for its robustness.</p>
</sec>
</sec>
</sec>
<sec sec-type="discussion" id="s5">
<title>Discussion</title>
<p>The current study was planned to test the mediation effects of both resilience and mental health for the relationship between loneliness and mental and physical QoL with a sample of elderly Italian people, given the lack of national and international literature concerning a multidimensional model of QoL, loneliness, resilience, and mental health. The best model from the current study supports the mediation effect of both resilience and mental health between loneliness and mental and physical QoL.</p>
<p>These results strongly suggest that loneliness influences mental and physical QoL via two pathways, with the impact of loneliness mediated by mental health and the impact of loneliness mediated by resilience. In other words, elderly people with high levels of loneliness are at an increased risk of experiencing low levels of mental health and low capacity to withstand stressors, resulting in low mental and physical QoL. The QoL seems to be the outcome of different psychological processes interrelated in a complex way, and not a direct effect of the perceived loneliness level.</p>
<p>Another relevant finding of the study regards the path of loneliness &#x02192; resilience &#x02192; mental health &#x02192; mental and physical QoL, which was shown to be significant. This path could underline that elderly people with high loneliness levels are not able to face adversity, trauma, or stress; persons in this condition may evidence a lower resilience level, which may threaten their mental health. In turn, this condition could lead to a lower mental and physical QoL. That is, mental health is a mediator between resilience and mental and physical QoL, while resilience partially mediates the relationship between loneliness and mental health.</p>
<p>In line with the literature (Fry and Debats, <xref ref-type="bibr" rid="B56">2010</xref>), the results of our study seem to indicate that people with greater levels of self-efficacy and resilience can mobilize emotional and psychological resources to face the stressful elements of their lives, and therefore, to express and feel more QoL satisfaction. According to the socio-cognitive model of health proposed by Bandura (<xref ref-type="bibr" rid="B6">1977</xref>, <xref ref-type="bibr" rid="B8">1986</xref>, <xref ref-type="bibr" rid="B9">1988</xref>), the concept of self-efficacy is included in a perspective that considers people as having an active role in producing and giving meaning to their experiences. These agency beliefs would affect the way in which the elderly face typical limitations and loss at their stage of life. In fact, according Lawton et al. (<xref ref-type="bibr" rid="B79">1999</xref>), maintaining a sense of agency can help a person to preserve a positive attitude toward life, moderating the emotional effect of loneliness and distress and supporting a greater life satisfaction.</p>
<p>In terms of clinical interventions, the model highlights how important the support that elderly people receive from social relationships could be. The reduction of loneliness dissatisfaction may be an important factor in primary prevention or the recovery process. Elderly people&#x00027;s active participation in social activities in their communities could be increased via specific initiatives aimed at the elderly population. The opportunity to reduce the level of mental distress has been evidenced in the model with increasing resilience and self-efficacy and reduced loneliness dissatisfaction. This reduction will strengthen the capacity to face adversity, different losses, and stressful situations (resilience). In addition, as evidenced by the literature, a high degree of resiliency contributes to increased perceived life quality at the physical and psychological levels, and at the same time, reduces anxiety and depressive symptoms. The fact that loneliness could be reduced (Findlay, <xref ref-type="bibr" rid="B49">2003</xref>; Cattan et al., <xref ref-type="bibr" rid="B35">2005</xref>; Fokkema and Van Tilburg, <xref ref-type="bibr" rid="B50">2007</xref>; Dickens et al., <xref ref-type="bibr" rid="B42">2011</xref>; Forsman et al., <xref ref-type="bibr" rid="B51">2011</xref>; Masi et al., <xref ref-type="bibr" rid="B87">2011</xref>; Hagan et al., <xref ref-type="bibr" rid="B63">2014</xref>), self-efficacy beliefs modified (Bandura, <xref ref-type="bibr" rid="B10">1993</xref>), and resilience strengthened (Hartling, <xref ref-type="bibr" rid="B64">2008</xref>) makes these factors primary for early intervention in support of QoL among the elderly (Fry and Debats, <xref ref-type="bibr" rid="B54">2002</xref>). Ultimately, the results could also have economic implications in term of reducing healthcare costs (Bramley et al., <xref ref-type="bibr" rid="B25">2002</xref>) and resulting in fewer contacts between elderly people and general practitioners and hospitals.</p>
<sec>
<title>Limits and future perspectives</title>
<p>Critically analyzing the outcomes of the present study, it could be interesting to consider the results in the context of the study&#x00027;s limitations. First, self-report tools were used, and they are not exempt from limitations, such as, inaccurate reporting and social desirability bias. Second, the participation in the study was voluntary; consequently, the sample composition may not represent the characteristics of the general Italian population. Third, the did not considered the variables of being in a couple (Ha, <xref ref-type="bibr" rid="B62">2016</xref>), having siblings (Cicirelli, <xref ref-type="bibr" rid="B37">2013</xref>), or being in a twin relationship (Brustia et al., <xref ref-type="bibr" rid="B29">2013</xref>; Prino et al., <xref ref-type="bibr" rid="B96">2016</xref>).</p>
<p>Future studies should examine and consider the relationship between mental health&#x02014;in terms of anxiety, depression, resilience, and QoL&#x02014;from a longitudinal perspective. For example, research could compare people&#x00027;s conditions at different stages in the Third Age or monitor longitudinal changes in the relationships between these factors in the lifecycle. Moreover, they could analyze people resilience and self-efficacy before and after completing a specific intervention program. It would also be interesting to further analyze the absence of the relationship between loneliness and QoL and to carry out the following: (1) pre&#x02013;post evaluation of a specific training program on increasing resilience and reducing loneliness in a group of elderly people to see if their QoL increases (Lloyd et al., <xref ref-type="bibr" rid="B82">2017</xref>); (2) consider the variable of being in a couple or whether the person a caregiver everyday life; and (3) consider older people who have experienced specific Third Age losses and study the evolution of the mediation model presented here.</p>
</sec>
</sec>
<sec id="s6">
<title>Ethics statement</title>
<p>This research project has been approved by Scientific Commission of &#x0201C;Fondazione Giovanni Goria&#x0201D; and everything has been done in accordance with the ethical standard of Associazione Italiana di Psicologia and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed sheet on the questionnaire was given and discussed with all individual participants included in the study and no identifying details (name, surname, dates of birth, identity numbers, and other information) of the participants that were studied has been gathered and collected. After the discussion on the information sheet and to have answered to the their questions about the issues on the administration/questionnaire, each participant gave oral consent before filling. Researchers don&#x00027;t have any opportunity to identify any specific participant.</p>
</sec>
<sec id="s7">
<title>Author contributions</title>
<p>EG prepared the study design, organized the sample recruitment, collected data, and contributed to the writing of the manuscript&#x00027;s introduction, discussion, and references sections. LR contributed to the study design and writing of the manuscript&#x00027;s introduction, discussion, and references sections. CS prepared the data set, performed statistical analysis, prepared the tables, and contributed to the writing of the methods and results sections. PB prepared the study design and supervised the research team.</p>
<sec>
<title>Conflict of interest statement</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
</sec>
</body>
<back>
<ack><p>A special thanks to the participants who made this study possible.A special thanks for the help to Mr. M. Bergaglia, Ms. G. Costa, Mr. A. Magliano, Ms. L. Patteri, and Mr. N. Utelle.</p>
</ack>
<ref-list>
<title>References</title>
<ref id="B1">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Akaike</surname> <given-names>H.</given-names></name></person-group> (<year>1987</year>). <article-title>Factor analysis and AIC</article-title>. <source>Psychometrika</source> <volume>52</volume>, <fpage>317</fpage>&#x02013;<lpage>332</lpage>. <pub-id pub-id-type="doi">10.1007/BF02294359</pub-id></citation></ref>
<ref id="B2">
<citation citation-type="web"><person-group person-group-type="author"><collab>American Psychological Association (APA)</collab></person-group> (<year>2004</year>). <source>Fostering Resilience in Response to Terrorism: For Psychologists Working with Older Adults</source>. Avaliable online at: <ext-link ext-link-type="uri" xlink:href="http://www.apa.org/pi/aging/resources/older-adults.pdf">http://www.apa.org/pi/aging/resources/older-adults.pdf</ext-link></citation></ref>
<ref id="B3">
<citation citation-type="web"><person-group person-group-type="author"><collab>American Psychological Association (APA)</collab></person-group> (<year>2011</year>). <source>The Road to Resilience</source>. Avaliable online at: <ext-link ext-link-type="uri" xlink:href="http://www.apa.org/helpcenter/road-resilience.aspx">http://www.apa.org/helpcenter/road-resilience.aspx</ext-link></citation></ref>
<ref id="B4">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Anderson</surname> <given-names>J. C.</given-names></name> <name><surname>Gerbing</surname> <given-names>D. W.</given-names></name></person-group> (<year>1988</year>). <article-title>Structural equation modeling in practice: a review and recommended two-step approach</article-title>. <source>Psychol. Bull.</source> <volume>103</volume>, <fpage>411</fpage>&#x02013;<lpage>423</lpage>. <pub-id pub-id-type="doi">10.1037/0033-2909.103.3.411</pub-id></citation></ref>
<ref id="B5">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Arkar</surname> <given-names>H.</given-names></name> <name><surname>Sari</surname> <given-names>&#x000D6;.</given-names></name> <name><surname>Fidaner</surname> <given-names>H.</given-names></name></person-group> (<year>2004</year>). <article-title>Relationships between quality of life, perceived social support, social network, and loneliness in a turkish sample</article-title>. <source>Yeni Symp.</source> <volume>42</volume>, <fpage>20</fpage>&#x02013;<lpage>27</lpage>.</citation></ref>
<ref id="B6">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bandura</surname> <given-names>A.</given-names></name></person-group> (<year>1977</year>). <article-title>Self-efficacy: toward a unifying theory of behavioral change</article-title>. <source>Psychol. Rev.</source> <volume>84</volume>, <fpage>191</fpage>&#x02013;<lpage>215</lpage>. <pub-id pub-id-type="doi">10.1037/0033-295X.84.2.191</pub-id><pub-id pub-id-type="pmid">847061</pub-id></citation></ref>
<ref id="B7">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bandura</surname> <given-names>A.</given-names></name></person-group> (<year>1982</year>). <article-title>Self-efficacy mechanism in human agency</article-title>. <source>Amer. Psychol.</source> <volume>37</volume>, <fpage>122</fpage>&#x02013;<lpage>147</lpage>. <pub-id pub-id-type="doi">10.1037/0003-066X.37.2.122</pub-id></citation></ref>
<ref id="B8">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Bandura</surname> <given-names>A.</given-names></name></person-group> (<year>1986</year>). <source>Social Foundations of Thought and Action: A Social Cognitive Theory</source>. <publisher-loc>Englewood Cliffs, NJ</publisher-loc>: <publisher-name>Prentice Hall</publisher-name>.</citation></ref>
<ref id="B9">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bandura</surname> <given-names>A.</given-names></name></person-group> (<year>1988</year>). <article-title>Self-efficacy conception of anxiety</article-title>. <source>Anxiet. Res.</source> <volume>1</volume>, <fpage>77</fpage>&#x02013;<lpage>98</lpage>. <pub-id pub-id-type="doi">10.1080/10615808808248222</pub-id></citation></ref>
<ref id="B10">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bandura</surname> <given-names>A.</given-names></name></person-group> (<year>1993</year>). <article-title>Perceived self-efficacy in cognitive development and functioning</article-title>. <source>Educ. Psychol.</source> <volume>28</volume>, <fpage>117</fpage>&#x02013;<lpage>148</lpage>. <pub-id pub-id-type="doi">10.1207/s15326985ep2802_3</pub-id></citation></ref>
<ref id="B11">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Bandura</surname> <given-names>A.</given-names></name></person-group> (<year>1997</year>). <source>Self-efficacy: The Exercise of Control</source>. <publisher-loc>New York, NY</publisher-loc>: <publisher-name>Freeman</publisher-name>.</citation></ref>
<ref id="B12">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Bandura</surname> <given-names>A.</given-names></name></person-group> (<year>2000</year>). <article-title>Self-efficacy: the foundation of agency,</article-title> in <source>Control of Human Behaviour, Mental Processes and Consciousness</source>, eds <person-group person-group-type="editor"><name><surname>Perrig</surname> <given-names>W. J.</given-names></name> <name><surname>Grob</surname> <given-names>A.</given-names></name></person-group> (<publisher-loc>Mahwak, NJ</publisher-loc>: <publisher-name>Erlbaum</publisher-name>), <fpage>17</fpage>&#x02013;<lpage>33</lpage>.</citation></ref>
<ref id="B13">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bandura</surname> <given-names>A.</given-names></name></person-group> (<year>2004</year>). <article-title>Health promotion by social cognitive means</article-title>. <source>Health Educ. Behav.</source> <volume>31</volume>, <fpage>143</fpage>&#x02013;<lpage>164</lpage>. <pub-id pub-id-type="doi">10.1177/1090198104263660</pub-id><pub-id pub-id-type="pmid">15090118</pub-id></citation></ref>
<ref id="B14">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Barg</surname> <given-names>F. K.</given-names></name> <name><surname>Huss-Ashmore</surname> <given-names>R.</given-names></name> <name><surname>Wittink</surname> <given-names>M. N.</given-names></name> <name><surname>Murray</surname> <given-names>G. F.</given-names></name> <name><surname>Bogner</surname> <given-names>H. R.</given-names></name> <name><surname>Gallo</surname> <given-names>J. J.</given-names></name></person-group> (<year>2006</year>). <article-title>A mixed-methods approach to understanding loneliness and depression in older adults</article-title>. <source>J. Gerontol. B Psychol. Sci. Soc. Sci.</source> <volume>61</volume>, <fpage>S329</fpage>&#x02013;<lpage>S339</lpage>. <pub-id pub-id-type="doi">10.1093/geronb/61.6.S329</pub-id><pub-id pub-id-type="pmid">17114313</pub-id></citation></ref>
<ref id="B15">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Baumeister</surname> <given-names>R. F.</given-names></name> <name><surname>DeWall</surname> <given-names>C. N.</given-names></name> <name><surname>Ciarocco</surname> <given-names>N. J.</given-names></name> <name><surname>Twenge</surname> <given-names>J. M.</given-names></name></person-group> (<year>2005</year>). <article-title>Social exclusion impairs self-regulation</article-title>. <source>J. Pers. Soc. Psychol.</source> <volume>88</volume>, <fpage>589</fpage>&#x02013;<lpage>604</lpage>. <pub-id pub-id-type="doi">10.1037/0022-3514.88.4.589</pub-id><pub-id pub-id-type="pmid">15796662</pub-id></citation></ref>
<ref id="B16">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Beekman</surname> <given-names>A. F.</given-names></name> <name><surname>Copeland</surname> <given-names>J. M.</given-names></name> <name><surname>Prince</surname> <given-names>M. J.</given-names></name></person-group> (<year>1999</year>). <article-title>Review of community prevalence of depression in later life</article-title>. <source>Br. J. Psychiatry</source> <volume>174</volume>, <fpage>307</fpage>&#x02013;<lpage>311</lpage>. <pub-id pub-id-type="doi">10.1192/bjp.174.4.307</pub-id><pub-id pub-id-type="pmid">10533549</pub-id></citation></ref>
<ref id="B17">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bentler</surname> <given-names>P. M.</given-names></name></person-group> (<year>1990</year>). <article-title>Comparative fit indexes in structural models</article-title>. <source>Psychol. Bull.</source> <volume>107</volume>, <fpage>238</fpage>&#x02013;<lpage>246</lpage>. <pub-id pub-id-type="doi">10.1037/0033-2909.107.2.238</pub-id><pub-id pub-id-type="pmid">2320703</pub-id></citation></ref>
<ref id="B18">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bj&#x000F8;rkl&#x000F8;f</surname> <given-names>G. H.</given-names></name> <name><surname>Engedal</surname> <given-names>K.</given-names></name> <name><surname>Selbaek</surname> <given-names>G.</given-names></name> <name><surname>Kouwenhoven</surname> <given-names>S. E.</given-names></name> <name><surname>Helvik</surname> <given-names>A.-S.</given-names></name></person-group> (<year>2013</year>). <article-title>Coping and depression in old age: a literature review</article-title>. <source>Dement. Geriatr. Cogn. Disord.</source> <volume>35</volume>, <fpage>121</fpage>&#x02013;<lpage>154</lpage>. <pub-id pub-id-type="doi">10.1159/000346633</pub-id><pub-id pub-id-type="pmid">23392253</pub-id></citation></ref>
<ref id="B19">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Blane</surname> <given-names>D.</given-names></name> <name><surname>Netuveli</surname> <given-names>G.</given-names></name> <name><surname>Montgomery</surname> <given-names>S. M.</given-names></name></person-group> (<year>2008</year>). <article-title>Quality of life, health and physiological status and change at older ages</article-title>. <source>Soc. Sci. Med.</source> <volume>66</volume>, <fpage>1579</fpage>&#x02013;<lpage>1587</lpage>. <pub-id pub-id-type="doi">10.1016/j.socscimed.2007.12.021</pub-id><pub-id pub-id-type="pmid">18241966</pub-id></citation></ref>
<ref id="B20">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Blazer</surname> <given-names>D. G.</given-names></name></person-group> (<year>2003</year>). <article-title>Depression in late life: review and commentary</article-title>. <source>J. Gerontol. A Biol. Sci. Med. Sci.</source> <volume>58</volume>, <fpage>249</fpage>&#x02013;<lpage>265</lpage>. <pub-id pub-id-type="doi">10.1093/gerona/58.3.M249</pub-id><pub-id pub-id-type="pmid">12634292</pub-id></citation></ref>
<ref id="B21">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bonanno</surname> <given-names>G. A.</given-names></name></person-group> (<year>2004</year>). <article-title>Loss, trauma, and human resilience: have we underestimated the human capacity to thrive after extremely aversive events?</article-title> <source>Am. Psychol.</source> <volume>59</volume>, <fpage>20</fpage>&#x02013;<lpage>28</lpage>. <pub-id pub-id-type="doi">10.1037/0003-066X.59.1.20</pub-id><pub-id pub-id-type="pmid">14736317</pub-id></citation></ref>
<ref id="B22">
<citation citation-type="book"><person-group person-group-type="editor"><name><surname>B&#x000F6;rsch-Supan</surname> <given-names>A.</given-names></name> <name><surname>Brugiavini</surname> <given-names>A.</given-names></name> <name><surname>J&#x000FC;rges</surname> <given-names>H.</given-names></name> <name><surname>Mackenbach</surname> <given-names>J.</given-names></name> <name><surname>Siegrist</surname> <given-names>J.</given-names></name> <name><surname>Weber</surname> <given-names>G.</given-names></name></person-group> (Eds) (<year>2005</year>). <source>Health, Ageing and Retirement in Europe &#x02013; First Results from the Survey of Health, Ageing and Retirement in Europe</source>. <publisher-loc>Mannheim</publisher-loc>: <publisher-name>Mannheim Research Institute for the Economics of Aging (MEA)</publisher-name>.</citation></ref>
<ref id="B23">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Bowling</surname> <given-names>A.</given-names></name></person-group> (<year>2001</year>). <source>Measuring Disease: A Review of Disease Specific Quality of Life Measurement Scales, 2nd Edn</source>. <publisher-loc>Buckingham</publisher-loc>: <publisher-name>Open University Press</publisher-name>.</citation></ref>
<ref id="B24">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bowling</surname> <given-names>A.</given-names></name> <name><surname>Banister</surname> <given-names>D.</given-names></name> <name><surname>Sutton</surname> <given-names>S.</given-names></name> <name><surname>Evans</surname> <given-names>O.</given-names></name> <name><surname>Windsor</surname> <given-names>J.</given-names></name></person-group> (<year>2002</year>). <article-title>A multidimensional model of the quality of life in older age</article-title>. <source>Aging Ment. Health</source> <volume>6</volume>, <fpage>355</fpage>&#x02013;<lpage>371</lpage>. <pub-id pub-id-type="doi">10.1080/1360786021000006983</pub-id><pub-id pub-id-type="pmid">12425770</pub-id></citation></ref>
<ref id="B25">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bramley</surname> <given-names>T. J.</given-names></name> <name><surname>Lerner</surname> <given-names>D.</given-names></name> <name><surname>Sarnes</surname> <given-names>M.</given-names></name></person-group> (<year>2002</year>). <article-title>Productivity losses related to the common cold</article-title>. <source>J. Occup. Environ. Med.</source> <volume>44</volume>, <fpage>822</fpage>&#x02013;<lpage>829</lpage>. <pub-id pub-id-type="doi">10.1097/00043764-200209000-00004</pub-id><pub-id pub-id-type="pmid">12227674</pub-id></citation></ref>
<ref id="B26">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Braudy Harris</surname> <given-names>P.</given-names></name></person-group> (<year>2008</year>). <article-title>Another wrinkle in the debate about successful aging: the undervalued concept of resilience and the lived experience of dementia</article-title>. <source>Int. J. Aging Hum. Dev.</source> <volume>67</volume>, <fpage>43</fpage>&#x02013;<lpage>61</lpage>. <pub-id pub-id-type="doi">10.2190/AG.67.1.c</pub-id></citation></ref>
<ref id="B27">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Brown</surname> <given-names>T.</given-names></name></person-group> (<year>2006</year>). <source>Confirmatory Factor Analysis for Applied Research</source>. <publisher-loc>New York, NY</publisher-loc>: <publisher-name>Guilford Press</publisher-name>.</citation></ref>
<ref id="B28">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Browne</surname> <given-names>M. W.</given-names></name> <name><surname>Cudeck</surname> <given-names>R.</given-names></name></person-group> (<year>1993</year>). <article-title>Alternative ways of assessing model fit,</article-title> in <source>Testing Structural Equations Models</source>, eds <person-group person-group-type="editor"><name><surname>Bollen</surname> <given-names>K. A.</given-names></name> <name><surname>Long</surname> <given-names>J. S.</given-names></name></person-group> (<publisher-loc>Newbury Park, CA</publisher-loc>: <publisher-name>Sage</publisher-name>), <fpage>136</fpage>&#x02013;<lpage>162</lpage>.</citation></ref>
<ref id="B29">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Brustia</surname> <given-names>P.</given-names></name> <name><surname>Gerino</surname> <given-names>E.</given-names></name> <name><surname>Roll&#x000E8;</surname> <given-names>L.</given-names></name></person-group> (<year>2013</year>). <article-title>Costruzione dell&#x00027;identit&#x000E0; e sviluppo emotivo nelle coppie gemellari: effetti sul benessere nel ciclo di vita</article-title>. <source>Psichiatr. Psicoter.</source> <volume>32</volume>, <fpage>181</fpage>&#x02013;<lpage>196</lpage>.</citation></ref>
<ref id="B30">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Byrne</surname> <given-names>B. M.</given-names></name></person-group> (<year>2001</year>). <source>Structural Equation Modeling with AMOS</source>. <publisher-loc>Rahwah, NJ</publisher-loc>: <publisher-name>Lawrence Erlbaum Associates</publisher-name>.</citation></ref>
<ref id="B31">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Byrne</surname> <given-names>G. J.</given-names></name> <name><surname>Pachana</surname> <given-names>N. A.</given-names></name></person-group> (<year>2011</year>). <article-title>Development and validation of a short form of the geriatric anxiety inventory &#x02013; the GAI-SF</article-title>. <source>Int. Psychogeriatr.</source> <volume>23</volume>, <fpage>125</fpage>&#x02013;<lpage>131</lpage>. <pub-id pub-id-type="doi">10.1017/S1041610210001237</pub-id><pub-id pub-id-type="pmid">20561386</pub-id></citation></ref>
<ref id="B32">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cacioppo</surname> <given-names>J. T.</given-names></name> <name><surname>Hawkley</surname> <given-names>L. C.</given-names></name> <name><surname>Thisted</surname> <given-names>R. A.</given-names></name></person-group> (<year>2010</year>). <article-title>Perceived social isolation makes me sad: 5-year cross-lagged analyses of loneliness and depressive symptomatology in the chicago health, aging, and social relations study</article-title>. <source>Psychol. Aging</source> <volume>25</volume>, <fpage>453</fpage>&#x02013;<lpage>463</lpage>. <pub-id pub-id-type="doi">10.1037/a0017216</pub-id><pub-id pub-id-type="pmid">20545429</pub-id></citation></ref>
<ref id="B33">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cacioppo</surname> <given-names>J. T.</given-names></name> <name><surname>Hughes</surname> <given-names>M. E.</given-names></name> <name><surname>Waite</surname> <given-names>L. J.</given-names></name> <name><surname>Hawkley</surname> <given-names>L. C.</given-names></name> <name><surname>Thisted</surname> <given-names>R. A.</given-names></name></person-group> (<year>2006</year>). <article-title>Loneliness as a specific risk factor for depressive symptoms: cross-sectional and longitudinal analyses</article-title>. <source>Psychol. Aging</source> <volume>21</volume>, <fpage>140</fpage>&#x02013;<lpage>151</lpage>. <pub-id pub-id-type="doi">10.1037/0882-7974.21.1.140</pub-id><pub-id pub-id-type="pmid">16594799</pub-id></citation></ref>
<ref id="B34">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Carstensen</surname> <given-names>L. L.</given-names></name> <name><surname>Fung</surname> <given-names>H. H.</given-names></name> <name><surname>Charles</surname> <given-names>S. T.</given-names></name></person-group> (<year>2003</year>). <article-title>Socioemotional selectivity theory and the regulation of emotion in the second half of life</article-title>. <source>Motiv. Emot.</source> <volume>27</volume>, <fpage>103</fpage>&#x02013;<lpage>123</lpage>. <pub-id pub-id-type="doi">10.1023/A:1024569803230</pub-id></citation></ref>
<ref id="B35">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cattan</surname> <given-names>C.</given-names></name> <name><surname>White</surname> <given-names>M.</given-names></name> <name><surname>Bond</surname> <given-names>J.</given-names></name> <name><surname>Learmouth</surname> <given-names>A.</given-names></name></person-group> (<year>2005</year>). <article-title>Preventing social isolation and loneliness among older people: a systematic review of health promotion interventions</article-title>. <source>Ageing Soc.</source> <volume>25</volume>, <fpage>41</fpage>&#x02013;<lpage>67</lpage>. <pub-id pub-id-type="doi">10.1017/S0144686X04002594</pub-id></citation></ref>
<ref id="B36">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Charney</surname> <given-names>D. S.</given-names></name></person-group> (<year>2004</year>). <article-title>Psychobiological mechanisms of resilience and vulnerability: implications for successful adaptation to extreme stress</article-title>. <source>Am. J. Psychiatry</source> <volume>161</volume>, <fpage>195</fpage>&#x02013;<lpage>216</lpage>. <pub-id pub-id-type="doi">10.1176/appi.ajp.161.2.195</pub-id><pub-id pub-id-type="pmid">14754765</pub-id></citation></ref>
<ref id="B37">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Cicirelli</surname> <given-names>V. G.</given-names></name></person-group> (<year>2013</year>). <source>Sibling Relationships Across the Life Span</source>. <publisher-loc>New York, NY</publisher-loc>: <publisher-name>Springer Science &#x00026; Business Media</publisher-name>.</citation></ref>
<ref id="B38">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Connor</surname> <given-names>K. M.</given-names></name> <name><surname>Zhang</surname> <given-names>W.</given-names></name></person-group> (<year>2006</year>). <article-title>Resilience: determinants, measurement, and treatment responsiveness</article-title>. <source>CNS Spectr</source> <volume>11</volume>, (<supplement>10 Suppl. 12</supplement>), <fpage>5</fpage>&#x02013;<lpage>12</lpage>. <pub-id pub-id-type="doi">10.1017/S1092852900025797</pub-id><pub-id pub-id-type="pmid">17008825</pub-id></citation></ref>
<ref id="B39">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>De Girolamo</surname> <given-names>G.</given-names></name> <name><surname>Rucci</surname> <given-names>P.</given-names></name> <name><surname>Scocco</surname> <given-names>P.</given-names></name> <name><surname>Becchi</surname> <given-names>A.</given-names></name> <name><surname>Coppa</surname> <given-names>F.</given-names></name> <name><surname>D&#x00027;Addario</surname> <given-names>A.</given-names></name> <etal/></person-group>. (<year>2000</year>). <article-title>Quality of life assessment: validation of the Italian version of the WHOQOL-Brief</article-title>. <source>Epidemiol. Psichiatr. Soc.</source> <volume>9</volume>, <fpage>45</fpage>&#x02013;<lpage>55</lpage>. <pub-id pub-id-type="doi">10.1017/S1121189X00007740</pub-id><pub-id pub-id-type="pmid">10859875</pub-id></citation></ref>
<ref id="B40">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>de Jager</surname> <given-names>C. A.</given-names></name> <name><surname>Budge</surname> <given-names>M. M.</given-names></name> <name><surname>Clarke</surname> <given-names>R.</given-names></name></person-group> (<year>2003</year>). <article-title>Utility of TICS-M for the assessment of cognitive function in older adults</article-title>. <source>Int. J. Geriatr. Psychiatry</source> <volume>18</volume>, <fpage>318</fpage>&#x02013;<lpage>324</lpage>. <pub-id pub-id-type="doi">10.1002/gps.830</pub-id><pub-id pub-id-type="pmid">12673608</pub-id></citation></ref>
<ref id="B41">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>DeSalvo</surname> <given-names>K. B.</given-names></name> <name><surname>Bloser</surname> <given-names>N.</given-names></name> <name><surname>Reynolds</surname> <given-names>K.</given-names></name> <name><surname>He</surname> <given-names>J.</given-names></name> <name><surname>Muntner</surname> <given-names>P.</given-names></name></person-group> (<year>2006</year>). <article-title>Mortality prediction with a single general self-rated health question. A meta-analysis</article-title>. <source>J. Gen. Intern. Med.</source> <volume>21</volume>, <fpage>267</fpage>&#x02013;<lpage>275</lpage>. <pub-id pub-id-type="doi">10.1111/j.1525-1497.2005.00291.x</pub-id><pub-id pub-id-type="pmid">16336622</pub-id></citation></ref>
<ref id="B42">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Dickens</surname> <given-names>A. P.</given-names></name> <name><surname>Richards</surname> <given-names>S. H.</given-names></name> <name><surname>Greaves</surname> <given-names>C. J.</given-names></name> <name><surname>Campbell</surname> <given-names>J. L.</given-names></name></person-group> (<year>2011</year>). <article-title>Interventions targeting social isolation in older people: a systematic review</article-title>. <source>BMC Public Health</source> <volume>11</volume>:<fpage>647</fpage>. <pub-id pub-id-type="doi">10.1186/1471-2458-11-647</pub-id><pub-id pub-id-type="pmid">21843337</pub-id></citation></ref>
<ref id="B43">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Djukanovic</surname> <given-names>I.</given-names></name> <name><surname>Sorjonen</surname> <given-names>K.</given-names></name> <name><surname>Petersona</surname> <given-names>U.</given-names></name></person-group> (<year>2015</year>). <article-title>Association between depressive symptoms and age, sex, loneliness and treatment among older people in Sweden</article-title>. <source>Aging Ment. Health</source> <volume>19</volume>, <fpage>560</fpage>- 568. <pub-id pub-id-type="doi">10.1080/13607863.2014.962001</pub-id><pub-id pub-id-type="pmid">25266255</pub-id></citation></ref>
<ref id="B44">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Ekwall</surname> <given-names>A. K.</given-names></name> <name><surname>Sivberg</surname> <given-names>B.</given-names></name> <name><surname>Hallberg</surname> <given-names>I. R.</given-names></name></person-group> (<year>2005</year>). <article-title>Loneliness as a predictor of quality of life among older caregivers</article-title>. <source>J. Adv. Nurs.</source> <volume>49</volume>, <fpage>23</fpage>&#x02013;<lpage>32</lpage>. <pub-id pub-id-type="doi">10.1111/j.1365-2648.2004.03260.x</pub-id><pub-id pub-id-type="pmid">15610378</pub-id></citation></ref>
<ref id="B45">
<citation citation-type="web"><person-group person-group-type="author"><collab>Eurostat</collab></person-group> (<year>2015a</year>). <source>People in the EU &#x02013; Statistics on Demographic Changes</source>. Avaliable online at: <ext-link ext-link-type="uri" xlink:href="http://ec.europa.eu/eurostat/statistics-explained/index.php/People_in_the_EU_%E2%80%93_statistics_on_demographic_changes">http://ec.europa.eu/eurostat/statistics-explained/index.php/People_in_the_EU_%E2%80%93_statistics_on_demographic_changes</ext-link></citation></ref>
<ref id="B46">
<citation citation-type="web"><person-group person-group-type="author"><collab>Eurostat</collab></person-group> (<year>2015b</year>). <source>People in the EU &#x02013; Statistics on an Ageing Society</source>. Avaliable online at: <ext-link ext-link-type="uri" xlink:href="http://ec.europa.eu/eurostat/statistics-explained/index.php/People_in_the_EU_%E2%80%93_statistics_on_an_ageing_society">http://ec.europa.eu/eurostat/statistics-explained/index.php/People_in_the_EU_%E2%80%93_statistics_on_an_ageing_society</ext-link></citation></ref>
<ref id="B47">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Fern&#x000E1;ndez-Ballesteros</surname> <given-names>R.</given-names></name></person-group> (<year>2003</year>). <article-title>Light and dark in the psychology of human strengths: The example of psychogerontology,</article-title> in <source>A Psychology of Human Strengths: Fundamental Questions and Future Directions for a Positive Psychology</source> eds <person-group person-group-type="editor"><name><surname>Aspinwal</surname> <given-names>K. G.</given-names></name> <name><surname>Staudinger</surname> <given-names>U. M.</given-names></name></person-group> (<publisher-loc>Washington, DC</publisher-loc>: <publisher-name>American Psychological Association</publisher-name>), <fpage>131</fpage>&#x02013;<lpage>147</lpage>.</citation></ref>
<ref id="B48">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Fern&#x000E1;ndez-Ballesteros</surname> <given-names>R.</given-names></name></person-group> (<year>2008</year>). <source>Active Aging. The contribution of Psychology</source>. <publisher-loc>G&#x000F6;ttingen</publisher-loc>: <publisher-name>Hogrefe and Huber</publisher-name>.</citation></ref>
<ref id="B49">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Findlay</surname> <given-names>R.</given-names></name></person-group> (<year>2003</year>). <article-title>Interventions to reduce social isolation amongst older people: where is the evidence?</article-title> <source>Ageing Soc.</source> <volume>23</volume>, <fpage>647</fpage>&#x02013;<lpage>658</lpage>. <pub-id pub-id-type="doi">10.1017/S0144686X03001296</pub-id></citation></ref>
<ref id="B50">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fokkema</surname> <given-names>C. M.</given-names></name> <name><surname>Van Tilburg</surname> <given-names>T. G.</given-names></name></person-group> (<year>2007</year>). <article-title>Zin en onzin van eenzaamheidsinterventies bij ouderen [Loneliness interventions among older adults: sense or nonsense?]</article-title>. <source>Tijdschr. Gerontol. Geriatr.</source> <volume>38</volume>, <fpage>185</fpage>&#x02013;<lpage>203</lpage>. <pub-id pub-id-type="doi">10.1007/BF03074846</pub-id></citation></ref>
<ref id="B51">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Forsman</surname> <given-names>A. K.</given-names></name> <name><surname>Nordmyr</surname> <given-names>J.</given-names></name> <name><surname>Wahlbeck</surname> <given-names>K.</given-names></name></person-group> (<year>2011</year>). <article-title>Psychosocial interventions for the promotion of mental health and the prevention of depression among older adults</article-title>. <source>Health Promot. Int.</source> <volume>26</volume>, <fpage>i85</fpage>&#x02013;<lpage>i107</lpage>. <pub-id pub-id-type="doi">10.1093/heapro/dar074</pub-id><pub-id pub-id-type="pmid">22079938</pub-id></citation></ref>
<ref id="B52">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fredrickson</surname> <given-names>B. L.</given-names></name> <name><surname>Tugade</surname> <given-names>M. M.</given-names></name> <name><surname>Waugh</surname> <given-names>C. E.</given-names></name> <name><surname>Larkin</surname> <given-names>G. R.</given-names></name></person-group> (<year>2003</year>). <article-title>What good are positive emotions in crisis? A prospective study of resilience and emotions following the terrorist attacks on the United States on September 11th, 2001</article-title>. <source>J. Pers. Soc. Psychol.</source> <volume>84</volume>, <fpage>365</fpage>&#x02013;<lpage>376</lpage>. <pub-id pub-id-type="doi">10.1037/0022-3514.84.2.365</pub-id></citation></ref>
<ref id="B53">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fry</surname> <given-names>P. S.</given-names></name></person-group> (<year>2001</year>). <article-title>Predictors of health quality life perspectives, self-esteem, and life satisfactions of older adults following spousal loss: an 18-month follow-up study of widows and widowers</article-title>. <source>Gerontologist</source> <volume>41</volume>, <fpage>787</fpage>&#x02013;<lpage>798</lpage>. <pub-id pub-id-type="doi">10.1093/geront/41.6.787</pub-id><pub-id pub-id-type="pmid">11723347</pub-id></citation></ref>
<ref id="B54">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fry</surname> <given-names>P. S.</given-names></name> <name><surname>Debats</surname> <given-names>D. L.</given-names></name></person-group> (<year>2002</year>). <article-title>Self-efficacy beliefs as predictors of loneliness and psychological distress in older adults</article-title>. <source>Int. J. Aging Hum. Dev.</source> <volume>55</volume>, <fpage>233</fpage>&#x02013;<lpage>269</lpage>. <pub-id pub-id-type="doi">10.2190/KBVP-L2TE-2ERY-BH26</pub-id><pub-id pub-id-type="pmid">12693547</pub-id></citation></ref>
<ref id="B55">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fry</surname> <given-names>P. S.</given-names></name> <name><surname>Debats</surname> <given-names>D. L.</given-names></name></person-group> (<year>2006</year>). <article-title>Sources of life strengths as predictors of late-life mortality and survivorship</article-title>. <source>Int. J. Aging Hum. Dev.</source> <volume>62</volume>, <fpage>303</fpage>&#x02013;<lpage>334</lpage>. <pub-id pub-id-type="doi">10.2190/3VAT-D77G-VCNQ-6T61</pub-id><pub-id pub-id-type="pmid">16739467</pub-id></citation></ref>
<ref id="B56">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Fry</surname> <given-names>P. S.</given-names></name> <name><surname>Debats</surname> <given-names>D. L.</given-names></name></person-group> (<year>2010</year>). <article-title>Sources of human life-strengths, resilience, and health</article-title>, in eds <source>New Frontiers in Resilient Aging: Life-Strengths and Well-Being in Late Life</source>, eds <person-group person-group-type="editor"><name><surname>Fry</surname> <given-names>P. S.</given-names></name> <name><surname>Keyes</surname> <given-names>C. L. M.</given-names></name></person-group> (<publisher-loc>Cambridge</publisher-loc>: <publisher-name>Cambridge University Press</publisher-name>), <fpage>15</fpage>&#x02013;<lpage>59</lpage>.</citation></ref>
<ref id="B57">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Fry</surname> <given-names>P. S.</given-names></name> <name><surname>Keyes</surname> <given-names>C. L. M.</given-names></name></person-group> (<year>2010</year>). <article-title>Introduction,</article-title> in <source>New Frontiers in Resilient Aging: Life-Strengths and Well-Being in Late Life</source>, eds <person-group person-group-type="editor"><name><surname>Fry</surname> <given-names>P. S.</given-names></name> <name><surname>Keyes</surname> <given-names>C. L. M.</given-names></name></person-group> (<publisher-loc>Cambridge</publisher-loc>: <publisher-name>Cambridge University Press</publisher-name>), <fpage>1</fpage>&#x02013;<lpage>14</lpage>.</citation></ref>
<ref id="B58">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gabriel</surname> <given-names>Z.</given-names></name> <name><surname>Bowling</surname> <given-names>A.</given-names></name></person-group> (<year>2004</year>). <article-title>Quality of life from the perspectives of older people</article-title>. <source>Ageing Soc.</source> <volume>24</volume>, <fpage>675</fpage>&#x02013;<lpage>691</lpage>. <pub-id pub-id-type="doi">10.1017/S0144686X03001582</pub-id></citation></ref>
<ref id="B59">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gattuso</surname> <given-names>S.</given-names></name></person-group> (<year>2003</year>). <article-title>Becoming a wise old woman: resilience and wellness in later life</article-title>. <source>Health Sociol. Rev.</source> <volume>12</volume>, <fpage>171</fpage>&#x02013;<lpage>177</lpage>. <pub-id pub-id-type="doi">10.5172/hesr.12.2.171</pub-id></citation></ref>
<ref id="B60">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gerino</surname> <given-names>E.</given-names></name> <name><surname>Marino</surname> <given-names>E.</given-names></name> <name><surname>Brustia</surname> <given-names>P.</given-names></name> <name><surname>Lyrakos</surname> <given-names>D. G.</given-names></name> <name><surname>Roll&#x000E8;</surname> <given-names>L.</given-names></name></person-group> (<year>2015</year>). <article-title>Quality of life in the third age: a research on risk and protective factors</article-title>. <source>Proc. Soc. Behav. Sci.</source> <volume>187</volume>, <fpage>217</fpage>&#x02013;<lpage>222</lpage>. <pub-id pub-id-type="doi">10.1016/j.sbspro.2015.03.041</pub-id></citation></ref>
<ref id="B61">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Golden</surname> <given-names>J.</given-names></name> <name><surname>Conroy</surname> <given-names>R. M.</given-names></name> <name><surname>Bruce</surname> <given-names>I.</given-names></name> <name><surname>Denihan</surname> <given-names>A.</given-names></name> <name><surname>Green</surname> <given-names>A.</given-names></name> <name><surname>Kirby</surname> <given-names>M.</given-names></name> <etal/></person-group>. (<year>2009</year>). <article-title>Loneliness, social support networks, mood and wellbeing in community-dwelling elderly</article-title>. <source>Int. J. Geriatr. Psychiatry</source> <volume>24</volume>, <fpage>694</fpage>&#x02013;<lpage>700</lpage>. <pub-id pub-id-type="doi">10.1002/gps.2181</pub-id><pub-id pub-id-type="pmid">19274642</pub-id></citation></ref>
<ref id="B62">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Ha</surname> <given-names>T. H.</given-names></name></person-group> (<year>2016</year>). <article-title>Development of the structural model of middle-aged men&#x00027;s subjective quality of life</article-title>. <source>J. Digital Convergence</source> <volume>14</volume>, <fpage>125</fpage>&#x02013;<lpage>135</lpage>. <pub-id pub-id-type="doi">10.14400/JDC.2016.14.5.125</pub-id></citation></ref>
<ref id="B63">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hagan</surname> <given-names>R.</given-names></name> <name><surname>Manktelow</surname> <given-names>R.</given-names></name> <name><surname>Taylor</surname> <given-names>B.</given-names></name> <name><surname>Mallet</surname> <given-names>J.</given-names></name></person-group> (<year>2014</year>). <article-title>Reducing loneliness amongst older people: a systematic search and narrative review</article-title>. <source>Aging Mental Health</source> <volume>18</volume>, <fpage>683</fpage>&#x02013;<lpage>693</lpage>. <pub-id pub-id-type="doi">10.1080/13607863.2013.875122</pub-id><pub-id pub-id-type="pmid">24437736</pub-id></citation></ref>
<ref id="B64">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hartling</surname> <given-names>L. M.</given-names></name></person-group> (<year>2008</year>). <article-title>Strengthening resilience in a risky world: it&#x00027;s all about relationships</article-title>. <source>Women Ther.</source> <volume>31</volume>, <fpage>51</fpage>&#x02013;<lpage>70</lpage>. <pub-id pub-id-type="doi">10.1080/02703140802145870</pub-id></citation></ref>
<ref id="B65">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hawkley</surname> <given-names>L. C.</given-names></name> <name><surname>Cacioppo</surname> <given-names>J. T.</given-names></name></person-group> (<year>2010</year>). <article-title>Loneliness matters: a theoretical and empirical review of consequences and mechanisms</article-title>. <source>Ann. Behav. Med.</source> <volume>40</volume>, <fpage>218</fpage>&#x02013;<lpage>227</lpage>. <pub-id pub-id-type="doi">10.1007/s12160-010-9210-8</pub-id><pub-id pub-id-type="pmid">20652462</pub-id></citation></ref>
<ref id="B66">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hawkley</surname> <given-names>L. C.</given-names></name> <name><surname>Thisted</surname> <given-names>R. A.</given-names></name> <name><surname>Cacioppo</surname> <given-names>J. T.</given-names></name></person-group> (<year>2009</year>). <article-title>Loneliness predicts reduced physical activity: cross-sectional &#x00026; longitudinal analyses</article-title>. <source>Health Psychol.</source> <volume>28</volume>, <fpage>354</fpage>&#x02013;<lpage>363</lpage>. <pub-id pub-id-type="doi">10.1037/a0014400</pub-id><pub-id pub-id-type="pmid">19450042</pub-id></citation></ref>
<ref id="B67">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hildon</surname> <given-names>Z.</given-names></name> <name><surname>Montgomery</surname> <given-names>S. M.</given-names></name> <name><surname>Blane</surname> <given-names>D.</given-names></name> <name><surname>Wiggins</surname> <given-names>R. D.</given-names></name> <name><surname>Netuveli</surname> <given-names>G.</given-names></name></person-group> (<year>2010</year>). <article-title>Examining resilience of quality of life in the face of health-related and psychosocial adversity at older ages: what is &#x0201C;right&#x0201D; about the way we age?</article-title> <source>Gerontologist</source> <volume>50</volume>, <fpage>36</fpage>&#x02013;<lpage>47</lpage>. <pub-id pub-id-type="doi">10.1093/geront/gnp067</pub-id><pub-id pub-id-type="pmid">19549715</pub-id></citation></ref>
<ref id="B68">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hoyl</surname> <given-names>M. T.</given-names></name> <name><surname>Alessi</surname> <given-names>C. A.</given-names></name> <name><surname>Harker</surname> <given-names>J. O.</given-names></name> <name><surname>Josephson</surname> <given-names>K. R.</given-names></name> <name><surname>Pietruszka</surname> <given-names>F. M.</given-names></name> <name><surname>Koelfgen</surname> <given-names>M.</given-names></name> <etal/></person-group>. (<year>1999</year>). <article-title>Development and testing of a five-item version of the geriatric depression scale</article-title>. <source>J. Am. Geriatr. Soc.</source> <volume>47</volume>, <fpage>873</fpage>&#x02013;<lpage>878</lpage>. <pub-id pub-id-type="doi">10.1111/j.1532-5415.1999.tb03848.x</pub-id><pub-id pub-id-type="pmid">10404935</pub-id></citation></ref>
<ref id="B69">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hu</surname> <given-names>L.</given-names></name> <name><surname>Bentler</surname> <given-names>P. M.</given-names></name></person-group> (<year>1999</year>). <article-title>Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives</article-title>. <source>Struct. Equ. Model.</source> <volume>6</volume>, <fpage>1</fpage>&#x02013;<lpage>55</lpage>. <pub-id pub-id-type="doi">10.1080/10705519909540118</pub-id></citation></ref>
<ref id="B70">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Inui</surname> <given-names>T. S.</given-names></name></person-group> (<year>2003</year>). <article-title>The need for an integrated biopsychosocial approach to research on successful aging</article-title>. <source>Ann. Intern. Med.</source> <volume>139</volume>, <fpage>391</fpage>&#x02013;<lpage>394</lpage>. <pub-id pub-id-type="doi">10.7326/0003-4819-139-5_Part_2-200309021-00002</pub-id><pub-id pub-id-type="pmid">12965963</pub-id></citation></ref>
<ref id="B71">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Jerusalem</surname> <given-names>M.</given-names></name> <name><surname>Schwarzer</surname> <given-names>R.</given-names></name></person-group> (<year>1986</year>). <article-title>Selbstwirksamkeit [Self-efficacy],</article-title> in <source>Skalen zur Befindlichkeit und Pers&#x000F6;nlichkeit. Research Report No. 5</source>, ed <person-group person-group-type="editor"><name><surname>Schwarzer</surname> <given-names>R.</given-names></name></person-group> (<publisher-loc>Berlin</publisher-loc>: <publisher-name>Freie Universit&#x000E4;t, Institut f&#x000FC;r Psychologie</publisher-name>), <fpage>15</fpage>&#x02013;<lpage>28</lpage>.</citation></ref>
<ref id="B72">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Jerusalem</surname> <given-names>M.</given-names></name> <name><surname>Schwarzer</surname> <given-names>R.</given-names></name></person-group> (<year>1992</year>). <article-title>Self-efficacy as a resource factor in stress appraisal processes,</article-title> in <source>Self-Efficacy: Thought Control of Action</source>, ed <person-group person-group-type="editor"><name><surname>Schwarzer</surname> <given-names>R.</given-names></name></person-group> (<publisher-loc>Washington, DC</publisher-loc>: <publisher-name>Hemisphere</publisher-name>), <fpage>195</fpage>&#x02013;<lpage>213</lpage>.</citation></ref>
<ref id="B73">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Jeste</surname> <given-names>D. V.</given-names></name> <name><surname>Savla</surname> <given-names>G. N.</given-names></name> <name><surname>Thompson</surname> <given-names>W. K.</given-names></name> <name><surname>Vahia</surname> <given-names>I. V.</given-names></name> <name><surname>Glorioso</surname> <given-names>D. K.</given-names></name> <name><surname>Martin</surname> <given-names>A. S.</given-names></name> <etal/></person-group>. (<year>2013</year>). <article-title>Older age is associated with more successful aging: role of resilience and depression</article-title>. <source>Am. J. Psychiatry</source> <volume>170</volume>, <fpage>188</fpage>&#x02013;<lpage>196</lpage>. <pub-id pub-id-type="doi">10.1176/appi.ajp.2012.12030386</pub-id></citation></ref>
<ref id="B74">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Kline</surname> <given-names>R. B.</given-names></name></person-group> (<year>2005</year>). <source>Principles and Practice of Structural Equation Modeling, 2nd Edn</source>, <publisher-loc>New York, NY</publisher-loc>: <publisher-name>The Guilford Press</publisher-name>.</citation></ref>
<ref id="B75">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Krause</surname> <given-names>N.</given-names></name></person-group> (<year>1994</year>). <article-title>Stressors in salient social roles and well-being in later life</article-title>. <source>J. Gerontol.</source> <volume>49</volume>, <fpage>137</fpage>&#x02013;<lpage>148</lpage>. <pub-id pub-id-type="doi">10.1093/geronj/49.3.P137</pub-id><pub-id pub-id-type="pmid">8169343</pub-id></citation></ref>
<ref id="B76">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Laditka</surname> <given-names>S. B.</given-names></name> <name><surname>Corwin</surname> <given-names>S. J.</given-names></name> <name><surname>Laditka</surname> <given-names>J.</given-names></name> <name><surname>Liu</surname> <given-names>R.</given-names></name> <name><surname>Tseng</surname> <given-names>W.</given-names></name> <name><surname>Wu</surname> <given-names>B.</given-names></name> <etal/></person-group>. (<year>2009</year>). <article-title>Attitudes about aging well among a diverse group of older Americans: implications for promoting cognitive health</article-title>. <source>Gerontologist</source> <volume>49</volume>, <fpage>S30</fpage>&#x02013;<lpage>S39</lpage>. <pub-id pub-id-type="doi">10.1093/geront/gnp084</pub-id><pub-id pub-id-type="pmid">19525215</pub-id></citation></ref>
<ref id="B77">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Lamond</surname> <given-names>A. J.</given-names></name> <name><surname>Depp</surname> <given-names>C. A.</given-names></name> <name><surname>Allison</surname> <given-names>M.</given-names></name> <name><surname>Langer</surname> <given-names>R.</given-names></name> <name><surname>Reichstadt</surname> <given-names>J.</given-names></name> <name><surname>Moore</surname> <given-names>D. J.</given-names></name> <etal/></person-group>. (<year>2009</year>). <article-title>Measurement and predictors of resilience among community-dwelling older women</article-title>. <source>J. Psychiatr. Res.</source> <volume>43</volume>, <fpage>148</fpage>&#x02013;<lpage>154</lpage>. <pub-id pub-id-type="doi">10.1016/j.jpsychires.2008.03.007</pub-id><pub-id pub-id-type="pmid">18455190</pub-id></citation></ref>
<ref id="B78">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Lawton</surname> <given-names>M. P.</given-names></name></person-group> (<year>1991</year>). <article-title>A multidimensional view of quality of life in frail elders,</article-title> in <source>The Concept and Measurement of Quality of Life in the Frail Elderly</source>, eds <person-group person-group-type="editor"><name><surname>Birren</surname> <given-names>J. E.</given-names></name> <name><surname>Lubben</surname> <given-names>J. E.</given-names></name> <name><surname>Rowe</surname> <given-names>J. C.</given-names></name> <name><surname>Deutchman</surname> <given-names>D. E.</given-names></name></person-group> (<publisher-loc>San Diego, CA</publisher-loc>: <publisher-name>Academic Press</publisher-name>), <fpage>3</fpage>&#x02013;<lpage>27</lpage>.</citation></ref>
<ref id="B79">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Lawton</surname> <given-names>M. P.</given-names></name> <name><surname>Moss</surname> <given-names>M.</given-names></name> <name><surname>Hoffman</surname> <given-names>C.</given-names></name> <name><surname>Grant</surname> <given-names>R.</given-names></name> <name><surname>Ten Have</surname> <given-names>T.</given-names></name> <name><surname>Kleban</surname> <given-names>M. H.</given-names></name></person-group> (<year>1999</year>). <article-title>Health, valuation of life, and the wish to live</article-title>. <source>Gerontologist</source> <volume>39</volume>, <fpage>406</fpage>&#x02013;<lpage>416</lpage>. <pub-id pub-id-type="doi">10.1093/geront/39.4.406</pub-id><pub-id pub-id-type="pmid">10495578</pub-id></citation></ref>
<ref id="B80">
<citation citation-type="other"><person-group person-group-type="author"><name><surname>LeRoy</surname> <given-names>A. S.</given-names></name> <name><surname>Murdock</surname> <given-names>K. W.</given-names></name> <name><surname>Jaremka</surname> <given-names>L. M.</given-names></name> <name><surname>Loya</surname> <given-names>A.</given-names></name> <name><surname>Fagundes</surname> <given-names>C. P.</given-names></name></person-group> (<year>2017</year>). <source>Loneliness Predicts Self-Reported Cold Symptoms After a Viral Challenge</source>. Health psychology: official journal of the Division of Health Psychology; American Psychological Association. <pub-id pub-id-type="pmid">28358524</pub-id></citation></ref>
<ref id="B81">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Liu</surname> <given-names>L.-J.</given-names></name> <name><surname>Guo</surname> <given-names>Q.</given-names></name></person-group> (<year>2007</year>). <article-title>Loneliness and health-related quality of life for the empty nest elderly in the rural area of a mountainous county in China</article-title>. <source>Quality Life Res.</source> <volume>16</volume>, <fpage>1275</fpage>&#x02013;<lpage>1280</lpage>. <pub-id pub-id-type="doi">10.1007/s11136-007-9250-0</pub-id><pub-id pub-id-type="pmid">17703375</pub-id></citation></ref>
<ref id="B82">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Lloyd</surname> <given-names>M.</given-names></name> <name><surname>Ramon</surname> <given-names>S.</given-names></name> <name><surname>Vakalopoulou</surname> <given-names>A.</given-names></name> <name><surname>Videm&#x00161;ek</surname> <given-names>P.</given-names></name> <name><surname>Meffan</surname> <given-names>C.</given-names></name> <name><surname>Roszczynska-Michta</surname> <given-names>J.</given-names></name> <etal/></person-group>. (<year>2017</year>). <article-title>Women&#x00027;s experiences of domestic violence and mental health: findings from a European empowerment project</article-title>. <source>Psychol. Viol.</source> <volume>7</volume>, <fpage>478</fpage>&#x02013;<lpage>487</lpage>. <pub-id pub-id-type="doi">10.1037/vio0000111</pub-id></citation></ref>
<ref id="B83">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Lucas-Carrasco</surname> <given-names>R.</given-names></name></person-group> (<year>2012</year>). <article-title>The WHO quality of life (WHOQOL) questionnaire: Spanish development and validation studies</article-title>. <source>Quality Life Res.</source> <volume>21</volume>, <fpage>161</fpage>&#x02013;<lpage>165</lpage>. <pub-id pub-id-type="doi">10.1007/s11136-011-9926-3</pub-id><pub-id pub-id-type="pmid">21611868</pub-id></citation></ref>
<ref id="B84">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Luszczynska</surname> <given-names>A.</given-names></name> <name><surname>Guti&#x000E9;rrez-Do-a</surname> <given-names>B.</given-names></name> <name><surname>Schwarzer</surname> <given-names>R.</given-names></name></person-group> (<year>2005</year>). <article-title>General self-efficacy in various domains of human functioning: evidence from five countries</article-title>. <source>Int. J. Psychol.</source> <volume>40</volume>, <fpage>80</fpage>&#x02013;<lpage>89</lpage>. <pub-id pub-id-type="doi">10.1080/00207590444000041</pub-id></citation></ref>
<ref id="B85">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>MacLeod</surname> <given-names>S.</given-names></name> <name><surname>Musich</surname> <given-names>S.</given-names></name> <name><surname>Hawkins</surname> <given-names>K.</given-names></name> <name><surname>Alsgaard</surname> <given-names>K.</given-names></name> <name><surname>Wicker</surname> <given-names>E. R.</given-names></name></person-group> (<year>2016</year>). <article-title>The impact of resilience among older adults</article-title>. <source>Geriatr. Nurs.</source> <volume>37</volume>, <fpage>266</fpage>&#x02013;<lpage>272</lpage>. <pub-id pub-id-type="doi">10.1016/j.gerinurse.2016.02.014</pub-id><pub-id pub-id-type="pmid">27055911</pub-id></citation></ref>
<ref id="B86">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Marshall</surname> <given-names>G. N.</given-names></name></person-group> (<year>1991</year>). <article-title>A multidimensional analysis of internal health locus of control beliefs: separating the wheat from the chaff?</article-title> <source>J. Pers. Soc. Psychol.</source> <volume>61</volume>, <fpage>483</fpage>&#x02013;<lpage>491</lpage>. <pub-id pub-id-type="doi">10.1037/0022-3514.61.3.483</pub-id><pub-id pub-id-type="pmid">1941520</pub-id></citation></ref>
<ref id="B87">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Masi</surname> <given-names>C. M.</given-names></name> <name><surname>Chen</surname> <given-names>H. Y.</given-names></name> <name><surname>Hawkley</surname> <given-names>L. C.</given-names></name> <name><surname>Cacioppo</surname> <given-names>J. T.</given-names></name></person-group> (<year>2011</year>). <article-title>A meta-analysis of interventions to reduce loneliness</article-title>. <source>Person. Soc. Psychol. Rev.</source> <volume>15</volume>, <fpage>219</fpage>&#x02013;<lpage>266</lpage>. <pub-id pub-id-type="doi">10.1177/1088868310377394</pub-id><pub-id pub-id-type="pmid">20716644</pub-id></citation></ref>
<ref id="B88">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Montross</surname> <given-names>L. P.</given-names></name> <name><surname>Depp</surname> <given-names>C.</given-names></name> <name><surname>Daly</surname> <given-names>J.</given-names></name> <name><surname>Reichstadt</surname> <given-names>J.</given-names></name> <name><surname>Golshan</surname> <given-names>S.</given-names></name> <name><surname>Moore</surname> <given-names>D.</given-names></name> <etal/></person-group>. (<year>2006</year>). <article-title>Correlates of self-rated successful aging among community-dwelling older adults</article-title>. <source>Am. J. Geriatr. Psychiatry</source> <volume>14</volume>, <fpage>43</fpage>&#x02013;<lpage>51</lpage>. <pub-id pub-id-type="doi">10.1097/01.JGP.0000192489.43179.31</pub-id><pub-id pub-id-type="pmid">16407581</pub-id></citation></ref>
<ref id="B89">
<citation citation-type="book"><person-group person-group-type="author"><collab>National Board of Health Welfare, Sweden</collab></person-group> (<year>2008</year>). <source>Older People&#x00027;s Mental Health. [In Swedish]</source>. <publisher-loc>Stockholm</publisher-loc>. Avaliable online at: <ext-link ext-link-type="uri" xlink:href="http://www.socialstyrelsen.se/publikationer2008/2008-131-20">http://www.socialstyrelsen.se/publikationer2008/2008-131-20</ext-link></citation></ref>
<ref id="B90">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Nilsson</surname> <given-names>G.</given-names></name> <name><surname>Ohrvik</surname> <given-names>J.</given-names></name> <name><surname>Lonnberg</surname> <given-names>I.</given-names></name> <name><surname>Hedberg</surname> <given-names>P.</given-names></name></person-group> (<year>2011</year>). <article-title>Low Psychological General Well-Being (PGWB) is associated with deteriorated 10-year survival in men but not in women among the elderly</article-title>. <source>Arch. Gerontol. Geriatr.</source> <volume>52</volume>, <fpage>167</fpage>&#x02013;<lpage>171</lpage>. <pub-id pub-id-type="doi">10.1016/j.archger.2010.03.010</pub-id></citation></ref>
<ref id="B91">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>O&#x00027;Dwyer</surname> <given-names>S.</given-names></name> <name><surname>Moyle</surname> <given-names>W.</given-names></name> <name><surname>van Wyk</surname> <given-names>S.</given-names></name></person-group> (<year>2013</year>). <article-title>Suicidal ideation and resilience in family careres of people with dementia: a pilot qualitative study</article-title>. <source>Aging Mental Health</source> <volume>17</volume>, <fpage>753</fpage>&#x02013;<lpage>760</lpage>. <pub-id pub-id-type="doi">10.1080/13607863.2013.789001</pub-id><pub-id pub-id-type="pmid">23611756</pub-id></citation></ref>
<ref id="B92">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>O&#x00027;Rourke</surname> <given-names>N.</given-names></name> <name><surname>Kupferschmidt</surname> <given-names>A. L.</given-names></name> <name><surname>Claxton</surname> <given-names>A.</given-names></name> <name><surname>Smith</surname> <given-names>J. Z.</given-names></name> <name><surname>Chappell</surname> <given-names>N.</given-names></name> <name><surname>Beattie</surname> <given-names>B. L.</given-names></name></person-group> (<year>2010</year>). <article-title>Psychological resilience predicts depressive symptoms among souses of person with Alzheimer&#x00027;s disease over time</article-title>. <source>Aging Mental Health</source> <volume>14</volume>, <fpage>984</fpage>&#x02013;<lpage>993</lpage>. <pub-id pub-id-type="doi">10.1080/13607863.2010.501063</pub-id></citation></ref>
<ref id="B93">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Peplau</surname> <given-names>L. A.</given-names></name> <name><surname>Perlman</surname> <given-names>D.</given-names></name></person-group> (<year>1982</year>). <article-title>Perspectives on loneliness,</article-title> in <source>Loneliness: A Sourcebook of Current Theory, Research and Therapy</source>, eds <person-group person-group-type="editor"><name><surname>Peplau</surname> <given-names>A. L.</given-names></name> <name><surname>Perlman</surname> <given-names>D.</given-names></name></person-group> (<publisher-loc>New York, NY</publisher-loc>: <publisher-name>John Wiley &#x00026; Sons</publisher-name>), <fpage>1</fpage>&#x02013;<lpage>18</lpage>.</citation></ref>
<ref id="B94">
<citation citation-type="web"><person-group person-group-type="author"><name><surname>Peveri</surname> <given-names>L.</given-names></name></person-group> (<year>2010</year>). <source>Resilienza e Regolazione delle Emozioni. Un Approccio Multimodale</source>. Available onlin at: <ext-link ext-link-type="uri" xlink:href="http://boa.unimib.it/bitstream/10281/7893/3/phd_unimib_707899.pdf">http://boa.unimib.it/bitstream/10281/7893/3/phd_unimib_707899.pdf</ext-link></citation></ref>
<ref id="B95">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Prieto-Flores</surname> <given-names>M. E.</given-names></name> <name><surname>Forjaz</surname> <given-names>M. J.</given-names></name> <name><surname>Fernandez-Mayoralas</surname> <given-names>G.</given-names></name> <name><surname>Rojo-Perez</surname> <given-names>F.</given-names></name> <name><surname>Martinez-Martin</surname> <given-names>P.</given-names></name></person-group> (<year>2011</year>). <article-title>Factors associated with loneliness of noninstitutionalized and institutionalized older adults</article-title>. <source>J. Aging Health</source> <volume>23</volume>, <fpage>177</fpage>&#x02013;<lpage>194</lpage>. <pub-id pub-id-type="doi">10.1177/0898264310382658</pub-id><pub-id pub-id-type="pmid">20881107</pub-id></citation></ref>
<ref id="B96">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Prino</surname> <given-names>L. E.</given-names></name> <name><surname>Roll&#x000E8;</surname> <given-names>L.</given-names></name> <name><surname>Sechi</surname> <given-names>C.</given-names></name> <name><surname>Patteri</surname> <given-names>L.</given-names></name> <name><surname>Ambrosoli</surname> <given-names>A.</given-names></name> <name><surname>Caldarera</surname> <given-names>A. M.</given-names></name> <etal/></person-group>. (<year>2016</year>). <article-title>Parental relationship with twins from pregnancy to 3 months: the relation among parenting stress, infant temperament, and well-being</article-title>. <source>Front. Psychol.</source> <volume>7</volume>:<fpage>1628</fpage>. <pub-id pub-id-type="doi">10.3389/fpsyg.2016.01628</pub-id><pub-id pub-id-type="pmid">27818641</pub-id></citation></ref>
<ref id="B97">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Reichstadt</surname> <given-names>J.</given-names></name> <name><surname>Depp</surname> <given-names>C. A.</given-names></name> <name><surname>Palinkas</surname> <given-names>L. A.</given-names></name> <name><surname>Folsom</surname> <given-names>D. P.</given-names></name> <name><surname>Jeste</surname> <given-names>D. V.</given-names></name></person-group> (<year>2007</year>). <article-title>Building blocks of successful aging: a focus group study of older adults&#x00027; perceived contributors to successful aging</article-title>. <source>Am. J. Geriatr. Psychiatry</source> <volume>15</volume>, <fpage>194</fpage>&#x02013;<lpage>201</lpage>. <pub-id pub-id-type="doi">10.1097/JGP.0b013e318030255f</pub-id><pub-id pub-id-type="pmid">17322132</pub-id></citation></ref>
<ref id="B98">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Rinaldi</surname> <given-names>P.</given-names></name> <name><surname>Mecocci</surname> <given-names>P.</given-names></name> <name><surname>Benedetti</surname> <given-names>C.</given-names></name> <name><surname>Ercolani</surname> <given-names>S.</given-names></name> <name><surname>Bregnocchi</surname> <given-names>M.</given-names></name> <name><surname>Menculini</surname> <given-names>G.</given-names></name> <etal/></person-group>. (<year>2003</year>). <article-title>Validation of the five-item geriatric depression scale in elderly subjects in three different settings</article-title>. <source>J. Am. Geriatr. Soc.</source> <volume>51</volume>, <fpage>694</fpage>&#x02013;<lpage>698</lpage>. <pub-id pub-id-type="doi">10.1034/j.1600-0579.2003.00216.x</pub-id><pub-id pub-id-type="pmid">12752847</pub-id></citation></ref>
<ref id="B99">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Russell</surname> <given-names>D. W.</given-names></name></person-group> (<year>1996</year>). <article-title>UCLA loneliness scale (Version 3): reliability, validity, and factor structure</article-title>. <source>J. Pers. Assess.</source> <volume>66</volume>, <fpage>20</fpage>&#x02013;<lpage>40</lpage>. <pub-id pub-id-type="doi">10.1207/s15327752jpa6601_2</pub-id><pub-id pub-id-type="pmid">8576833</pub-id></citation></ref>
<ref id="B100">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Ryff</surname> <given-names>C. D.</given-names></name> <name><surname>Singer</surname> <given-names>B.</given-names></name></person-group> (<year>2000</year>). <article-title>Interpersonal Flourishing: a positive health agenda for the New Millennium</article-title>. <source>Pers. Soc. Psychol. Rev.</source> <volume>4</volume>, <fpage>30</fpage>&#x02013;<lpage>44</lpage>. <pub-id pub-id-type="doi">10.1207/S15327957PSPR0401_4</pub-id></citation></ref>
<ref id="B101">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sachs-Ericsson</surname> <given-names>N.</given-names></name> <name><surname>Kendall-Tacket</surname> <given-names>K. A.</given-names></name> <name><surname>Sheffler</surname> <given-names>J.</given-names></name> <name><surname>Arce</surname> <given-names>D.</given-names></name> <name><surname>Rushing</surname> <given-names>N. C.</given-names></name> <name><surname>Cosentino</surname> <given-names>E.</given-names></name></person-group> (<year>2014</year>). <article-title>The influence of prior rape on the psychological and physical health functioning of older adults</article-title>. <source>Aging Mental Health</source> <volume>18</volume>, <fpage>717</fpage>&#x02013;<lpage>730</lpage>. <pub-id pub-id-type="doi">10.1080/13607863.2014.884538</pub-id><pub-id pub-id-type="pmid">24521090</pub-id></citation></ref>
<ref id="B102">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Schoevers</surname> <given-names>R. A.</given-names></name> <name><surname>Beekman</surname> <given-names>A. T.</given-names></name> <name><surname>Van Tillburg</surname> <given-names>W.</given-names></name> <name><surname>Deeg</surname> <given-names>D. J.</given-names></name> <name><surname>Jonker</surname> <given-names>C.</given-names></name> <name><surname>Geerlings</surname> <given-names>M. I.</given-names></name> <etal/></person-group>. (<year>2000</year>). <article-title>Association of depression and gender with mortality in old age. Results from the Amsterdam Study of the Elderly (AMSTEL)</article-title>. <source>Br. J. Psychiatry</source> <volume>177</volume>, <fpage>336</fpage>&#x02013;<lpage>342</lpage>. <pub-id pub-id-type="doi">10.1192/bjp.177.4.336</pub-id><pub-id pub-id-type="pmid">11116775</pub-id></citation></ref>
<ref id="B103">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Schumacker</surname> <given-names>R. E.</given-names></name> <name><surname>Lomax</surname> <given-names>R. G.</given-names></name></person-group> (<year>1996</year>). <source>A Beginner s Guide to Structural Equation Modeling</source>. <publisher-loc>Mahwah, NJ</publisher-loc>: <publisher-name>Erlbaum</publisher-name>.</citation></ref>
<ref id="B104">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Settersten</surname> <given-names>R. A.</given-names></name> <name><surname>Godlewski</surname> <given-names>B.</given-names></name></person-group> (<year>2016</year>). <article-title>Concepts and theories of age and aging,</article-title> in <source>Handbook of Theories of Aging, 3rd Edn</source>, eds <person-group person-group-type="editor"><name><surname>Bengtson</surname> <given-names>V. L.</given-names></name> <name><surname>Settersten</surname> <given-names>R. A.</given-names></name></person-group> (<publisher-loc>New York, NY</publisher-loc>: <publisher-name>Spriger Publishing Company, LLC</publisher-name>), <fpage>9</fpage>&#x02013;<lpage>26</lpage>.</citation></ref>
<ref id="B105">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sharpley</surname> <given-names>C. F.</given-names></name> <name><surname>Yardley</surname> <given-names>P.</given-names></name></person-group> (<year>1999</year>). <article-title>The relationship between cognitive hardiness, explanatory style, and depression-happiness in post-retirement men and women</article-title>. <source>Aust. Psychol.</source> <volume>34</volume>, <fpage>198</fpage>&#x02013;<lpage>203</lpage>. <pub-id pub-id-type="doi">10.1080/00050069908257454</pub-id></citation></ref>
<ref id="B106">
<citation citation-type="web"><person-group person-group-type="author"><name><surname>Sibilia</surname> <given-names>L.</given-names></name> <name><surname>Schwarzer</surname> <given-names>R.</given-names></name> <name><surname>Jerusalem</surname> <given-names>M.</given-names></name></person-group> (<year>1995</year>). <source>Italian Adaptation of the General Self-Efficacy Scale</source>. Available online at: <ext-link ext-link-type="uri" xlink:href="http://userpage.fu-berlin.de/&#x0007E;health/italian.htm">http://userpage.fu-berlin.de/&#x0007E;health/italian.htm</ext-link></citation></ref>
<ref id="B107">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Smith</surname> <given-names>G. C.</given-names></name> <name><surname>Kohn</surname> <given-names>S. J.</given-names></name> <name><surname>Savage-Stevens</surname> <given-names>S. E.</given-names></name> <name><surname>Finch</surname> <given-names>J. J.</given-names></name> <name><surname>Ingate</surname> <given-names>R.</given-names></name> <name><surname>Lim</surname> <given-names>Y.</given-names></name></person-group> (<year>2000</year>). <article-title>The effects of interpersonal and personal agency on perceivedcontrol and psychological well-being in adulthood</article-title>. <source>Gerontologist</source> <volume>40</volume>, <fpage>458</fpage>&#x02013;<lpage>468</lpage>. <pub-id pub-id-type="doi">10.1093/geront/40.4.458</pub-id><pub-id pub-id-type="pmid">10961035</pub-id></citation></ref>
<ref id="B108">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Smith</surname> <given-names>J. L.</given-names></name> <name><surname>Hollinger-Smith</surname> <given-names>L.</given-names></name></person-group> (<year>2015</year>). <article-title>Savoring, resilience, and psychological well-being in older adults</article-title>. <source>Aging Ment. Health</source> <volume>19</volume>, <fpage>192</fpage>&#x02013;<lpage>200</lpage>. <pub-id pub-id-type="doi">10.1080/13607863.2014.986647</pub-id><pub-id pub-id-type="pmid">25471325</pub-id></citation></ref>
<ref id="B109">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Smith-Osborne</surname> <given-names>A.</given-names></name> <name><surname>Felderhoff</surname> <given-names>B.</given-names></name></person-group> (<year>2016</year>). <article-title>Formal and family caregiver protective factors in systems of care: a systematic review with implications toward a resilience model for aging veterans</article-title>. <source>Traumatology</source> <volume>22</volume>, <fpage>29</fpage>&#x02013;<lpage>39</lpage>. <pub-id pub-id-type="doi">10.1037/trm0000056</pub-id></citation></ref>
<ref id="B110">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Stephens</surname> <given-names>C.</given-names></name> <name><surname>Breheny</surname> <given-names>M.</given-names></name> <name><surname>Mansvelt</surname> <given-names>J.</given-names></name></person-group> (<year>2015</year>). <article-title>Healthy ageing from the perspective of older people: a capability approach to resilience</article-title>. <source>Psychol. Health</source> <volume>30</volume>, <fpage>715</fpage>&#x02013;<lpage>731</lpage>. <pub-id pub-id-type="doi">10.1080/08870446.2014.904862</pub-id><pub-id pub-id-type="pmid">24678916</pub-id></citation></ref>
<ref id="B111">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Theeke</surname> <given-names>A. L.</given-names></name></person-group> (<year>2010</year>). <article-title>Sociodemographic and health-related risks for loneliness and outcome differences by loneliness status in a sample of U.S. older adults</article-title>. <source>Res. Gerontol. Nurs.</source> <volume>3</volume>, <fpage>113</fpage>&#x02013;<lpage>125</lpage>. <pub-id pub-id-type="doi">10.3928/19404921-20091103-99</pub-id><pub-id pub-id-type="pmid">20415360</pub-id></citation></ref>
<ref id="B112">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Theeke</surname> <given-names>A. L.</given-names></name></person-group> (<year>2012</year>). <article-title>Older people who report loneliness have increased risk of mortality and functional decline</article-title>. <source>Evid Based Nurs.</source> <volume>172</volume>, <fpage>1078</fpage>&#x02013;<lpage>1083</lpage>. <pub-id pub-id-type="doi">10.1136/eb-2012-101052</pub-id></citation></ref>
<ref id="B113">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Tiikkainen</surname> <given-names>P.</given-names></name> <name><surname>Heikkinen</surname> <given-names>R. L.</given-names></name></person-group> (<year>2005</year>). <article-title>Associations between loneliness, depressive symptoms and perceived togetherness in older people</article-title>. <source>Aging Mental Health</source> <volume>9</volume>, <fpage>526</fpage>&#x02013;<lpage>534</lpage>. <pub-id pub-id-type="doi">10.1080/13607860500193138</pub-id><pub-id pub-id-type="pmid">16214700</pub-id></citation></ref>
<ref id="B114">
<citation citation-type="other"><person-group person-group-type="author"><collab>United Nations (UN)</collab></person-group> (<year>2002</year>). <source>World Population Prospects: The 2000 Revision.</source> Analytical report. United Nations, New York, NY.</citation></ref>
<ref id="B115">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Vahia</surname> <given-names>I. V.</given-names></name> <name><surname>Thompson</surname> <given-names>W. K.</given-names></name> <name><surname>Depp</surname> <given-names>C. A.</given-names></name> <name><surname>Allison</surname> <given-names>M.</given-names></name> <name><surname>Jeste</surname> <given-names>D. V.</given-names></name></person-group> (<year>2012</year>). <article-title>Developing a dimensional model for successful cognitive and emotional aging</article-title>. <source>Int. Psychogeriatr.</source> <volume>24</volume>, <fpage>515</fpage>&#x02013;<lpage>523</lpage>. <pub-id pub-id-type="doi">10.1017/S1041610211002055</pub-id><pub-id pub-id-type="pmid">22050770</pub-id></citation></ref>
<ref id="B116">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wagnild</surname> <given-names>G.</given-names></name></person-group> (<year>2009</year>). <article-title>A review of the resilience scale</article-title>. <source>J. Nurs. Meas.</source> <volume>17</volume>, <fpage>105</fpage>&#x02013;<lpage>113</lpage>. <pub-id pub-id-type="doi">10.1891/1061-3749.17.2.105</pub-id><pub-id pub-id-type="pmid">19711709</pub-id></citation></ref>
<ref id="B117">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wagnild</surname> <given-names>G. M.</given-names></name> <name><surname>Young</surname> <given-names>H. G.</given-names></name></person-group> (<year>1993</year>). <article-title>Development and psychometric evaluation of the resilience scale</article-title>. <source>J. Nurs. Meas.</source> <volume>1</volume>, <fpage>165</fpage>&#x02013;<lpage>178</lpage>. <pub-id pub-id-type="pmid">7850498</pub-id></citation></ref>
<ref id="B118">
<citation citation-type="book"><person-group person-group-type="author"><name><surname>Wallace</surname> <given-names>K. A.</given-names></name></person-group> (<year>2003</year>). <article-title>An examination of hardiness in male older adults living in a rural setting,</article-title> in <source>Advances in Psychology Research</source>, <volume>Vol. 23</volume>, ed <person-group person-group-type="editor"><name><surname>Shovov</surname> <given-names>S. P.</given-names></name></person-group> (<publisher-loc>Hauppauge</publisher-loc>: <publisher-name>Nova Science Publishers</publisher-name>), <fpage>78</fpage>&#x02013;<lpage>94</lpage>.</citation></ref>
<ref id="B119">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wild</surname> <given-names>K.</given-names></name> <name><surname>Wiles</surname> <given-names>J. L.</given-names></name> <name><surname>Allen</surname> <given-names>R. E. S.</given-names></name></person-group> (<year>2013</year>). <article-title>Resilience: thoughts on the value of the concept for critical gerontology</article-title>. <source>Aging Soc.</source> <volume>33</volume>, <fpage>137</fpage>&#x02013;<lpage>158</lpage>. <pub-id pub-id-type="doi">10.1017/S0144686X11001073</pub-id></citation></ref>
<ref id="B120">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wiles</surname> <given-names>J. L.</given-names></name> <name><surname>Wild</surname> <given-names>K.</given-names></name> <name><surname>Kerse</surname> <given-names>N.</given-names></name> <name><surname>Allen</surname> <given-names>R. E. S.</given-names></name></person-group> (<year>2012</year>). <article-title>Resilience from the point of view of older people: &#x0201C;there&#x00027;s still life beyond a funny knee</article-title>. <source>Soc. Sci. Med.</source> <volume>74</volume>, <fpage>416</fpage>&#x02013;<lpage>424</lpage>. <pub-id pub-id-type="doi">10.1016/j.socscimed.2011.11.005</pub-id></citation></ref>
<ref id="B121">
<citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wong</surname> <given-names>N.</given-names></name> <name><surname>Liu</surname> <given-names>H.</given-names></name> <name><surname>Lin</surname> <given-names>C.</given-names></name> <name><surname>Huang</surname> <given-names>C.</given-names></name> <name><surname>Wai</surname> <given-names>Y.</given-names></name> <name><surname>Lee</surname> <given-names>S.</given-names></name> <etal/></person-group>. (<year>2016</year>). <article-title>Loneliness in late-life depression: structural and functional connectivity during affective processing</article-title>. <source>Psychol. Med.</source> <volume>46</volume>, <fpage>2485</fpage>&#x02013;<lpage>2499</lpage>. <pub-id pub-id-type="doi">10.1017/S0033291716001033</pub-id><pub-id pub-id-type="pmid">27328861</pub-id></citation></ref>
<ref id="B122">
<citation citation-type="book"><person-group person-group-type="author"><collab>World Health Organization (WHO)</collab></person-group> (<year>1993</year>). <source>Measuring Quality of Life: The Development of the World Health Organization Quality of Life Instrument (WHOQOL)</source>. <publisher-name>WHO</publisher-name>, <publisher-loc>Geneva</publisher-loc>.</citation></ref>
<ref id="B123">
<citation citation-type="book"><person-group person-group-type="author"><collab>World Health Organization (WHO)</collab></person-group> (<year>2002</year>). <source>Active Ageing: a Policy Framework</source>. <publisher-name>World Health Organization</publisher-name>, <publisher-loc>Geneva</publisher-loc>. Avaliable online at: <ext-link ext-link-type="uri" xlink:href="http://whqlibdoc.who.int/hq/2002/who_nmh_nph_02.8.pdf">http://whqlibdoc.who.int/hq/2002/who_nmh_nph_02.8.pdf</ext-link> (Accessed April 19, 2017).</citation></ref>
<ref id="B124">
<citation citation-type="book"><person-group person-group-type="author"><collab>World Health Organization (WHO)</collab></person-group> (<year>2015</year>). <source>World Report on Aging and Health</source>. <publisher-name>World Health Organization</publisher-name>, <publisher-loc>Geneva</publisher-loc>. Avaliable onlne at: <ext-link ext-link-type="uri" xlink:href="http://apps.who.int/iris/bitstream/10665/186463/1/9789240694811_eng.pdf">http://apps.who.int/iris/bitstream/10665/186463/1/9789240694811_eng.pdf</ext-link> (Accessed April 19, 2017). <pub-id pub-id-type="pmid">28346562</pub-id></citation></ref>
</ref-list>
<fn-group>
<fn fn-type="financial-disclosure"><p><bold>Funding.</bold> The first part of this research was supported by a grant, titled &#x0201C;Solitudine e Qualit&#x000E0; della Vita nella popolazione anziana: validazione della UCLA Loneliness Scale (Versione 3) e costruzione di un modello esplicativo della Qualit&#x000E0; della Vita nella terza et&#x000E0;,&#x0201D; from &#x0201C;Progetto Master dei Talenti della Societ&#x000E0; Civile&#x0201D;&#x02014;Giovanni Goria and CRT Foundations (Italy) to EG (Ph.D).</p>
</fn>
</fn-group>
</back>
</article>
