One of the mental diseases connected to exposure to a traumatic or stressful incident is post-traumatic stress disorder (PTSD), which is characterized by intrusion, avoidance, fluctuating mood and cognition, and hyperarousal that lasts for more than a month after the stressful event. Examples of traumatic or stressful events include rape, torture, civil war, vicious physical attacks, accidents, natural catastrophes, murder, threats, kidnapping, the death of loved ones or friends, the loss of a house, and starvation (1, 2). According to the WHO’s Global Disease Burden Survey, mental illness, especially diseases related to stress, will rank as the second-leading cause of disability by the year 2023 (3). Every year, about 8 million adults worldwide have PTSD (4).

The prevalence of PTSD in the general population is becoming higher, particularly in post-conflict and conflict-ridden societies (5). According to studies of the general population, PTSD prevalence ranges between 1 and 5% (6, 7), While it has been shown to range from 3 to 58% in high-risk groups, such as those in conflict areas (7). In 2021, one of the bloodiest civil wars in history in northern Ethiopia drew international attention. The Tigray People’s Liberation Front (TPLF) party and the Ethiopian National Defense Forces (ENDF) were engaged in a civil war (8). Due to this fight, thousands of individuals lost their lives, and many more suffered injuries and traumatic events as they struggled to survive. Additionally, due to violent threats of rape, torture, mutilation, and destruction of property, nearly 2 million people were forced into internally displaced people’s camps (IDPs). Many of them, including children, were kidnaped, making them more vulnerable to psychological disorders, especially post-traumatic stress disorder (PTSD). The TPLF occupied the town of Nefas Meewcha in the Amhara Region between August 12 and August 21, 2021. According to an Amnesty International report, Tigrayan fighters looted medical institutions and private property in addition to mass rapes, gang rapes, physical attacks, and verbal assaults against women (9).

Mental health issues are a significant public health issue on a global scale, accounting for 14% of the total burden of disease (3). A new report from the Norwegian Refugee Council (NRC) and the Internal Displacement Monitoring Center (IDMC) for 2018 estimates that 30.6 million people worldwide were internally displaced due to conflict and disaster, with the majority residing in low-income nations that are occasionally hit by internal conflict and violence. In 2016, nearly 12.6 million people were internally displaced by violence in Africa (10). Studies have revealed severe mental health effects of wars and genocides around the world, impacting both veterans and civilians (11).

According to the results of a meta-analysis, an estimated 242 million adult war survivors living in post-conflict areas were affected by PTSD, while major depressive disorder affects an estimated 238 million adult war survivors (12). The prevalence of PTSD, which adds to the global burden of disease, is estimated to be around 4% worldwide (4). Another systematic review reported that 3–88% of people in the population have PTSD (13, 14). Additionally, a cross-sectional assessment at community levels in Nepal during the conflict time indicated that the prevalence of PTSD was 53.4% (15). Another study on Palestinian refugees in refugee camps during the Al-Aqsa intifada found that post-traumatic stress disorder was reported to be 68.9% (16). In addition, studies conducted among internally displaced people in Nigeria, Africa, revealed that the prevalence of PTSD was 63% (17), in Morocco 19.3% (18), and in South Sudan 28% (19). According to some Ethiopian studies, the Maikadra Massacre victims from the country’s northwest region had a prevalence of 59.8% PTSD (20), and PTSD affects 58.4% of internally displaced people in South Ethiopia (10). Another study’s results from West Ethiopia found that 17.1% of traumatized patients overall had PTSD (21). The prevalence of PTSD was 37.3% in community-based, cross-sectional research on landslide survivors in Addis Abeba, Ethiopia (1). According to a fairly recent community-based, cross-sectional study done in Dessie, Ethiopia, the prevalence of PTSD was 19.4% (22).

Despite the high prevalence of PTSD in conflict areas around the world, only a few studies with highly variable estimates of its prevalence have been reported in Ethiopia, where armed conflict, ethnic violence, and terrorist attacks are on the rise (20, 22). Most of the studies previously conducted rely on self-reporting questionnaires on PTSD symptoms, which gives different prevalence. In addition, it is imperative to do research in this field to provide scientific support for the formulation of prevention and treatment plans for mental health issues during the current and future civilian attacks. Therefore, the purpose of this study is to determine the prevalence of PTSD and associated risk factors among those who have gone through traumatic experiences in the armed conflict-affected town of Nefas Meewcha. The results of this study will assist medical experts, non-profit organizations, and psychological facilities in creating suitable strategies and treatments to deliver evidence-based treatment for PTSD patients.

War is complicated and may leave populations permanently traumatized. PTSD is the most common psychopathology and a serious public health concern after trauma or disaster (29). Populations affected by conflict are more likely to experience psychological discomfort and a variety of mental health issues (30). This population-based study aimed to assess the prevalence of PTSD in northwest Ethiopia following the civil war. The study’s findings indicated that PTSD was more common in the studied communities. Additionally, due to the high prevalence of PTSD in the study areas, well-coordinated public mental health measures must be launched. In order to improve people’s ability to function regularly and contribute to society, it is crucial to lessen the prevalence of mental diseases, notably post-traumatic stress disorder (PTSD) (31).

The results of the current study showed that among war survivors with a 95% CI of 36.2–46.7%, the prevalence of PTSD was 40.8%. This result was in line with those from research done in Gonder and Felege-Hiwot compressive specialized hospitals (37.2%) (32), in Addis Ababa, Ethiopia, Koshe Land Slide Survivors (37.3%) (1), and in Jewish Holocaust survivors (39%) (33). However, the prevalence of PTSD in the current study was lower than that reported in Keneya, which reported a prevalence rate of PTSD of 60% (34), 63% in North Eastern Nigeria (35), 59.8% in Maikadra town, North West Ethiopia (20), 58.4% among internally displaced individuals in Ethiopia (10) and 52.9% in Kenya (36). The variability in level of PTSD observed among the different African countries may result from the type of trauma and durations experienced by the study population (greater exposure to multiple types of traumatic events may expose greater PTSD severity).

In contrast, this study found a greater prevalence of PTSD than the studies carried out in Somalia, Jigiga (16.3%) (37), and in South Asia (7.27%) (38). The length of the vulnerable period, the degree of exposure to traumatic events, the tools and cut-off points used to evaluate PTSD, and the study design may all play a role in the discrepancy. Other variances could result from how data was collected and how studies were carried out in the aftermath of the attack.

Regarding the associated factors of physical assault (2.12 times), poor social support (1.47 times), being a housewife (1.9 times), and being single (1.48 times), they were more likely to develop PTSD. This study revealed that the odds of developing PTSD were 1.98 times higher in females compared to males. This report was comparable to studies done in south Ethiopiain Addis Ababa, Ethiopia (1), and in Mikadra, Ethiopia (20). This could be because women are more likely than men to experience psycho-trauma due to a lower threshold, or it could be a direct psychological effect of rape or other sexual abuse (39, 40). When compared to married people, the odds of developing PTSD were 3.6 times higher among widowed individuals. This report was consistent with studies on PTSD among UK military personnel (41).

Study participants whose close friends or family members suffered major injuries during the war had 4.5 times higher odds of developing PTSD. This report was consistent with previous studies of the Maikadra Massacre (20), the Rwandan Genocide (42), and the Peru earthquake (43). The odds of developing PTSD among individuals who had moderate and severe perceived threats to life were 3.5 and 5.2 times greater, respectively, which is consistent with another Ethiopian study (20). The odds of developing PTSD among those with symptoms of depression and anxiety were five times higher as compared to their counterparts. This is consistent with research on veterans held in the King County Jail system in Seattle, King County, Washington, and Kenya (44–46). This might be a result of the fact that participants with depressive and anxiety symptoms are more likely to have PTSD than respondents without depressive and anxiety symptoms (35).

Finally yet importantly, we discovered that participants who had a history of chronic medical conditions were 3.5 times more likely to experience PTSD than their counterparts. Similar to what has been discovered in previous studies from Kenya (47), South Korea (48). Participants with a history of a chronic medical condition may exhibit greater neurochemical imbalance and neuronal damage than participants without such a history. As a result, when exposed to stressful conditions, people with neuron-chemical imbalance caused by a history of chronic illness develop PTSD more quickly (35).

We used a sizable sample of the population, and the findings may be helpful to nations in the area devastated by the war. Due to the cross-sectional nature of the study, we were not able to verify whether the depressive and anxiety symptoms, as well as substance use, preceded or followed the PTSD. We did not use a structured clinical interview to ascertain the diagnosis of PTSD. Furthermore, this is a community survey; sampling was not intended to be representative according to relevant characteristics. Another limitation was the lack of previously validated Amharic versions of questioners.

In this study, the prevalence of PTSD was found to be high (40.8%). Having a family member or close friend injured or killed, having poor social support, being female, being screened positive for depression and anxiety, and having a chronic medical illness were all associated with PTSD with a p-value less than 0.05. The concerned organization may then practice techniques that can be used for early detection, prevention, and intervention to reduce the incidence of PTSD in war survivors.

The raw data supporting the conclusion of this article will be made available by the authors, without undue reservation.

The studies involving human participants were reviewed and approved by Health Science College Ethics Committee of Debre Tabor University. The patients/participants provided their written informed consent to participate in this study.

AAT contributed to study conception and design, data analysis, interpretation, and manuscript drafting. ECA, MAM, TSY, MJT, MAS, and NDB contributed to the conceptual idea of the manuscript. GWA, GYY, and YMM contributed in drafting the objectives and wrote the manuscript. All authors were involved in reviewing the final draft of the manuscript, revision of the manuscript, and approved the submitted version.