The initial effect of drought on the plants is the poor germination and impaired seedling establishment. Various studies have reported the negative impacts of drought stress on germination and seedling growth (Kaya et al., 2006; Farooq et al., 2009b). The reduction in germination potential, early seedling growth, root and shoot dry weight, hypocotyl length, and vegetative growth have been reported in important field crops including, pea (Pisum sativum L.), alfalfa (Medicago sativa L.), and rice (Oryza sativa L.) under drought stress (Okcu et al., 2005; Manikavelu et al., 2006; Zeid and Shedeed, 2006). Plant growth is mainly accomplished by cell division, enlargement, and differentiation. Drought impairs mitosis and cell elongation which results in poor growth (Hussain et al., 2008). Drought limits the process of cell growth mainly due to the loss of turgor (Taiz and Zeiger, 2006). Water limiting conditions results in impaired cell elongation mainly because of the poor water flow from xylem to the nearby cells (Nonami, 1998). Number of leaves and the size of individual leaf are also reduced under the drought conditions. The expansion of the leaf normally depends upon the turgor pressure and the supply of assimilates. Reduced turgor pressure and slow rate of photosynthesis under drought conditions mainly limit the leaf expansion (Rucker et al., 1995). Fresh and dry weights are also severely reduced under the water limiting conditions (Zhao et al., 2006). Plant height, leaf size, and the stem girth were significantly reduced under the water limiting conditions in maize (Khan et al., 2015). In another study, Kamara et al. (2003) reported that the biomass accumulation in maize was significantly reduced under drought conditions imposed at various growth stages.

Under the tropical climates the excessive radiations and elevated temperatures are another major limiting factor to plant growth and development. High temperatures may cause scorching of the twigs and leaves along with visual symptoms of sunburn, leaves senescence, growth inhibition and discoloration of fruits and leaves (Ismail and Hall, 1999; Vollenweider and Gunthardt-Goerg, 2005). Elevated temperatures can reduce the germination potential of the seeds and, thus, results in poor germination and stand establishment. Adverse effects of high temperature on cereal crops vary with the timing, duration, and sternness of the heat stress (Fahad et al., 2016b). High temperature stress reduced number of spikes and number of florets per plant in rice and seed-set in sorghum was also negatively affected under similar conditions (Prasad et al., 2006; Fahad et al., 2016b). Inside a floret, anthers, and pollens were more susceptible to high temperature than ovules. Under high temperature (≥30°C), floret sterility has been correlated with diminished anther dehiscence, poor shedding of pollens, poor germination of pollen grains on the stigma, decreased elongation of pollen tubes and reduced in vivo pollen germination (Fahad et al., 2015b, 2016b). A significant reduction in the growth and net assimilation rate was observed in maize and sugarcane (Saccharum officinarum L.) under heat stress (Ashraf and Hafeez, 2004; Wahid and Close, 2007). Ebrahim et al. (1998) reported a significant reduction in the inter-nodal length and biomass accumulation along with early leaf senescence in sugarcane under heat stress.

Yield is basically the complex integration of the different physiological processes. Most of these physiological processes are negatively affected by the drought stress. The negative impacts of drought on the yield mainly depend upon the severity of the stress and the plant growth stage. Significant yield losses have been reported in major field crops due to drought stress (Table 1). The drought induced at the pre-anthesis stage shortened the time to anthesis while that applied after anthesis reduced the period of grain filling in cereals (Estrada-Campuzano et al., 2008). The process of the grain filling in cereals is controlled by four major enzymes, i.e., Sucrose Synthase, Starch Synthase, Starch Branching Enzyme, and Adenosine Diphosphate Glucose Pyrophosphorylase (Taiz and Zeiger, 2006). A decreased activity of these enzymes has been reported under the drought conditions which have a negative impact on the yield of major cereal (Ahmadi and Baker, 2001). The exposure of plants to drought stress at the flowering may result in complete sterility in pearl millet (Pennisetum glaucum L.) which is usually due to the disturbed assimilate movement to the developing ear (Yadav et al., 2004).

Drought induced reduction in the yield might be due to various factors such as decreased rate of photosynthesis (Flexas et al., 2004), disturbed assimilate partitioning (Farooq et al., 2009b), or poor flag leaf development (Rucker et al., 1995). The exposure of maize to drought conditions at the tasseling stage resulted in a significant yield loss (Anjum et al., 2011). Similarly, a significant reduction in the boll production and the abortion of the produced bolls was recorded in cotton under drought conditions which ultimately affected the lint yield (Pettigrew, 2004). A significant reduction in the grain yield of barley (Hordeum vulgare L.) was also observed under drought conditions mainly because of less number of fertile tillers and grains along with less 1000 grain weight (Samarah, 2005). The exposure of pigeon pea (Cajanus cajan L.) to drought stress at the flowering stage caused over 50% reduction in the seed yield (Nam et al., 2001).

In temperate regions the high temperature shocks during the reproductive phase can cause substantial reduction in the yield of major cereals. The quality of the final produce in cereals and oilseed crops are also negatively affected by heat stress as it reduces the oil, starch, and protein contents substantially (Wilhelm et al., 1999; Maestri et al., 2002). Ferris et al. (1998) reported a significant decline in the grain weight and total number of grains in wheat under elevated temperatures. Temperature stress reduced rice yield by reducing the performance of different rice growth and yield traits. Fahad et al. (2016a) reported that tillering was very sensitive to elevated night temperature in rice. The grain weights for a rice cultivar are nearly stable in a stress-free environment (Mohammed and Tarpley, 2010), however, under high night temperature, a decrease in individual grain weight resulted in significant reduction in rice grain production per unit area (Fahad et al., 2016a). Heat stress caused substantial yield reductions in common beans (Phaseolus vulgaris L.) and peanut (Arachis hypogea L.) (Vara Parasad et al., 1999; Rainey and Griffiths, 2005). A major effect of the heat stress is commonly noticed in tomato (Lycopersicum esculentum Mill.) as it influences meiosis, fertilization, and growth of fertilized embryo ultimately causing a noticeable reduction in the yield (Camejo et al., 2005).

Drought and heat stress causes significant reductions in growth and yield of several important crops; however, the extent of damage depends upon crop growth stage and severity of the stress. In general, the reproductive phase is more sensitive to the stresses causing a substantial reduction in the yield.

Water relations are influenced by certain factors including the leaf water potential, leaf and canopy temperature, transpiration rate, and stomatal conductance. Exposure to drought stress disturbs all these factors in plants however, stomatal conductance is affected the most (Farooq et al., 2009b). A significant reduction in the leaf water potential and transpiration rate was observed under the drought conditions which ultimately increased the leaf and canopy temperature (Turner et al., 2001). Another important feature for plant physiological regulation is water use efficiency which is the ratio of the dry matter accumulated to the water consumed (Monclus et al., 2006). Efficient cultivars of wheat have higher water use efficiency under drought stress (Abbate et al., 2004). This improvement in the water use efficiency is mainly due to the accumulation of the dry matter by consuming less amount of water due to the closing of stomata and less rate of transpiration. A reduced water use efficiency was observed in potato (Solanum tuberosum L.) when exposed to an early season water shortage and it ultimately resulted in poor biomass accumulation and yield (Costa et al., 1997).

Drought stress greatly impacts the nutrient relations of the plants. Many important nutrients including, nitrogen, silicon, magnesium, and calcium are uptaken by roots along with water, the drought conditions limit the movement of these nutrients via diffusion and mass which leads to retarded plant growth (Barber, 1995). Plants increase the length and surface area of roots and change their architecture in order to capture the less mobile nutrients (Lynch and Brown, 2001). The soil moisture deficit at times reduce the growth of the roots and, hence, reduce the uptake of the less mobile nutrients such as phosphorus (Garg, 2003). Root–microbe interactions also play an important role in nutrient relations of a plant. The impaired carbon and oxygen flux to the nodules coupled with N accumulation under drought stress inhibited N fixing ability of certain legumes (Ladrera et al., 2007). Composition and activity of the soil microbial colonies are negatively affected by the soil water deficit which eventually disturb the plant nutrient relations (Schimel et al., 2007). The responses to the mineral uptake under moisture stress varies across the crop species. In general, N uptake is increased, P uptake is declined and potassium remains unaffected under drought conditions. However, nutrient relations become more complicated due to interactive effects of different nutrients on each other and overall plant physiology. This aspect requires detailed research at a sophisticated molecular level.

Plant water status is of prime importance under changing temperature conditions. Generally, the plants try to stabilize their tissue water content irrespective of temperature changes when the ample quantity of moisture is available; however, the temperature increase proves fatal under limited supply of water (Machado and Paulsen, 2001). Unfortunately, heat stress commonly coincides with the water scarcity under field condition especially in tropical and sub-tropical environments (Simoes-Araujo et al., 2003). Rapid reduction in leaf tissue water contents was observed in sugarcane on exposure to high temperature despite of the fact that the ample quantity of water was available in the soil (Wahid and Close, 2007). It shows that heat stress could also have a negative impact on the root conductance. Similar reduction in water content and root conductance has also been reported in tomato under heat stress (Morales et al., 2003). Generally, water loss under heat stress is more during day time mainly due to increased rate of transpiration, ultimately impairing certain important physiological processes in plants. Heat stress also reduces the number, mass and growth of the roots which ultimately limit the supply of water and nutrients to the above ground parts of the plant (Wahid et al., 2007; Huang et al., 2012).

Very little information is available regarding the direct impact of heat stress on the nutrient relations of crops (Basirirad, 2000; Rennenberg et al., 2006). Activity of the major enzymes like nitrate reductase involved in the nutrient metabolism can also be significantly reduced under high temperature stress (Klimenko et al., 2006). Reduction in nutrient uptake under heat stress might be due to various factors such as reduced root mass and nutrient uptake per unit root area (Basirirad, 2000). Overall, drought and heat stresses affect nutrient cycling, uptake and availability to plants by hampering different physiological functions of plants (Table 2).

Drought disturbs the balance of assimilates as most of them are translocated to the roots in order to improve water uptake (Leport et al., 2006). The export of assimilates from source to sink generally depends upon the rate of photosynthesis and the sucrose concentration in leaves (Komor, 2000). Drought impairs the process of photosynthesis and decrease the sucrose content which ultimately reduce the export rate from source to sink (Kim et al., 2000). Drought also limits the ability of the sink to utilize the incoming assimilates efficiently (Zinselmeier et al., 1999). Moreover, the activity of acid invertase is negatively affected which disrupts the phloem loading and unloading. In this way, dry matter partitioning is badly effected under moisture stress.

Reduction in the activities of source and sink takes place under heat stress which greatly effects the growth and ultimately the economic yield (Taiz and Zeiger, 2006). However, a considerable variation was reported among different wheat genotypes regarding assimilate partitioning under heat stress (Yang et al., 2002). Dinar and Rudich (1985) reported that the transport of the C to the apex was significantly reduced in two heat sensitive cultivars of tomato. Wardlaw (1974) examined the response of source, sink and transport pathway to high temperature stress in wheat and found that the photosynthesis rate was optimum at 20–30°C, however, an abrupt decline was noticed above 30°C. Loading of assimilates from the flag leaves also followed the same trend (Wardlaw, 1974). However the movement within the stem was found independent of the temperature from 1 to 50°C. It was concluded that the effect of heat stress on assimilate partitioning in wheat was indirectly related to the abnormal behavior of source and sink in addition to the decreased photosynthesis rate. From such observations we can suggest that the improvement of the mobilization efficiency of assimilates from leaves and other plants parts can be an important strategy for improving grain filling in the cereals.

Plant breeding using typical old techniques has proved very handy for the identification of stress-tolerant genetic traits in various crops and cultivars and the transfer of those traits into the cultivars having good agronomic performance (Ashraf, 2010). A significant progress has been made by the international research institutes to develop cultivars with noticeable drought tolerance (Table 4). One good example is the breeding effort started by CIMMYT for improving the tolerance in the maize against drought and common diseases. These hybrids were found best under drought in terms of overall plant growth and the economic yield. In 2006, a drought resistant cultivar of maize, Obatanpa GH, was developed by Crops Research Institute, Ghana in collaboration with CIMMYT and IITA which helped for food security in drought-hit regions (Badu-Apraku and Yallou, 2009). Similarly, IITA has also developed 16 inbred lines of maize having a certain degree of tolerance against drought (Badu-Apraku and Yallou, 2009).

Wheat is an important cereal crop around the globe and according to an estimate nearly 50% of the area under wheat cultivation is subjected to periodic drought. At CIMMYT, a diploid wild relative of bread wheat (Aegilops tauschii) was crossed with a tetraploid (Triticum turgidum) to produce a hexaploid having a significant tolerance against major abiotic stresses (Valkoun, 2001). Similar efforts are also in progress in IRRI, Philippines for the development of drought tolerant rice cultivars using classic breeding approaches. It will further improve the adoption of direct-seeded rice. Plant breeders and researchers at ICARDA and ICRISAT are also working to develop the drought tolerant cultivars of major cereals and leguminous crops (Ashraf, 2010).

Drought tolerance in the plants is a complex phenomenon being controlled by a large number of minor genes and loci on chromosomes having those genes called as QTL (Mohammadi et al., 2005). The Exploitation of the genetic variation among the existing cultivars for stress tolerance can be either done by natural selection under stressful environment or by QTLs mapping followed by marker assisted selection approach (Ashraf et al., 2008). Mapping of the QTLs basically helps in the assessment of total number of genes, their location and action pattern. A major problem associated with the selection of a proper QTL for the drought tolerance is a high degree interaction between QTL and environment (Tuberosa and Salvi, 2006). Therefore, once a QTL is identified for drought tolerance, isogenization is mandatory for its proper characterization (Salvi and Tuberosa, 2005). Mapping of the QTLs for the traits related to drought tolerance has been done in variety of crop species as enlisted in earlier reviews (Ashraf, 2010; Farooq et al., 2014; Lata et al., 2015). In cotton, a set of 33 QTLs was identified under water shortage conditions by using F₃ families of a cross between Gossypium barbadence and Gossypium hirsutum (Saranga et al., 2001). Out of those 33 QTLs, five were related to physiological traits, 11 to plant productivity and 17 to fiber quality. Recently the NILs had also been developed by shifting the QTLs for yield and other traits among G. barbadence and G. hirsutum (Levi et al., 2009). A large number of QTLs associated with drought tolerance has also been identified in rice (Lafitte et al., 2007). Another study identified 36 related to root growth and five related to osmotic adjustment in rice (Zhang et al., 2001). The Deeper Rooting 1 (DRO1) has proven to be a very useful QTL for drought tolerance as it increases root length in plants. For instance, Uga et al. (2013) reported significant yield improvement in shallow rooted rice cultivars after the introduction of DRO1.

After the identification of the proper QTLs, the next important part is their manipulation in order to develop drought tolerant cultivars. Steele et al. (2006) improved the root morphological characters in an Indian rice cultivar “Kalinga III” through marker assisted back crossing approach where a japonica cultivar “Azucena” from Philippines was used as donor. Five fragments on different chromosomes were selected for introgression. Among them four contained the QTLs for improved root morphology while one had QTL for aroma. Steele et al. (2007) evaluated four NILs under drought and observed improvement in grain and straw yields. Certain QTLs responsible for drought tolerance has also been identified in pearl millet by the breeders at ICRISAT (Serraj et al., 2004). The introgression lines developed by the marker assisted back crossing of the identified QTLs in the drought sensitive variety resulted in improved yield and better drought tolerance (Serraj et al., 2005). The stay green character under water limiting condition in sorghum was also improved by this approach (Harris et al., 2007). All these studies clearly show that QTL mapping and marker assisted breeding can play a vital role in improving the crop tolerance against drought stress. Although the achievements made so far seems simple, correct identification of the QTLs and proper application of marker assisted techniques is a complicated and expensive task.

Modern breeding approaches involving QTL mapping have not been used extensively for heat stress tolerance. The QTLs related to different traits involved in heat tolerance such as grain filling duration and leaf senescence have been identified in wheat (Mason et al., 2010). Farooq et al. (2011) also listed several QTLs identified for heat tolerance in wheat during reproductive stage. The QTLs related to grain filling duration in wheat under high temperature were identified on chromosome number 1B and 5A (Yang et al., 2002). A set of nine QTLs for tillering and three QTLs for stay green character has also been identified in wheat (Kumar et al., 2010; Li et al., 2010). Moreover, a set of four QTLs in Arabidopsis and 11 QTLs in maize were identified playing an important role in thermo-tolerance (Frova and Sari-Gorla, 1994).

A wide range of markers associated with the QTLs of heat tolerance has been identified, however, their actual role in marker assisted selection is very limited (Kumar et al., 2013). However, the simple sequence repeat markers linked with different heat tolerance characters were used recently in marker assisted selection among 25 wheat genotypes for heat tolerance (Sadat et al., 2013). The research work for identifying markers linked to heat tolerance has great scope and requires more effort.

Transgenic approaches involve modifications in the qualitative as well as the quantitative traits through transfer of desired genes (Ashraf, 2010). The major emphasis has been on the engineering of the genes which encode growth regulators, compatible solutes, and antioxidants involved in stress tolerance. The genes encoding two enzymes (choline mono oxygenase and beta aldehyde dehydrogenase) responsible for glycine betaine expression in higher plants have been successfully engineered to develop drought tolerant crops (Zhang et al., 2008). An inbred line of maize (DH4866) has also been produced by transferring a beta gene from Escherichia coli resulting in improved glycine betaine production and ultimately better drought tolerance (Quan et al., 2004). Similarly, the genes encoding the enzyme involved in the biosynthesis of another important osmolyte, proline, have been engineered in various crops including, soybean [Glycine max (L.) Merr.] and tobacco (Nicotiana tabacum L.) (Ronde et al., 2004; Gubis et al., 2007). The genes regulated by DREB and AREB protein are also being studied for drought stress tolerance in several crops (Singh and Laxmi, 2015). Recently, Kudo et al. (2017) reported that double overexpression of DREB1A and OsPIL1 genes improved drought tolerance in transgenic plants. Similarly, a large number of genes related to NAC family have been identified for stress tolerance in sugarcane (Ramaswamy et al., 2017).

Different types of the antioxidants are produced by the plants which play an important role in improving tolerance against the oxidative damage (Sunkar et al., 2006). Genes involved in the production and expression of SOD has been engineered and to produce drought tolerant transgenic alfalfa, potato and rice (Perl et al., 1993; McKersie et al., 1996; Wang et al., 2005). Similarly, transgenic tobacco has also been produced showing the over expression of ascorbate peroxidase and mono dehydro-ascorbate reductase (Eltayeb et al., 2007). Accumulation of the LEA proteins also plays an important role in drought tolerance (Gosal et al., 2009). The LEA proteins help plants in maintaining the cell membrane structure and ionic balance under drought stress (Browne et al., 2002). In the recent years, efforts have been put forth to engineer the genes involved in the production of LEA proteins. Transgenic lines of wheat, sorghum, and rice have been developed by transferring such genes to improve drought tolerance (Xu et al., 1994; Cheng et al., 2002). The drought tolerance capacity of transgenic crops depends on the crop growth stage and intensity of stress (Reddy et al., 2004; Ashraf, 2010). Further research is required to produce more transgenic crops with higher yield potential.

Significant progress has also been made in identification of the genes involved in various mechanisms of heat tolerance and their manipulation using various transgenic approaches (Zhang et al., 2001; Bonhert et al., 2006). Genetic manipulations for over-expression of SOD under heat stress has proved successful (Sairam and Tyagi, 2004). A transgenic tobacco plant showing a better photosynthetic activity under heat stress has been produced by alteration of the chloroplast membranes (Murakami et al., 2000). An enhanced tolerance against high temperature was reported in tobacco by the transfer of a gene Dnak1 (Ono et al., 2001). The transgenic plants having better production of glycine betaine due to transfer a gene (BADH) showed more tolerance to heat stress (Yang et al., 2005). The improved tolerance against heat stress can also be achieved by over expression of the HSPs through genetic manipulations. A transgenic tobacco plant was produced by the transfer of MT-sHSP from tomato for better thermo-tolerance (Sanmiya et al., 2004). Similarly, HSFs and DREB2A genes have been identified to engineer heat tolerant transgenic plants (Ohama et al., 2017).

Exogenous application of growth regulators and osmo-protectants at different growth stages can play an important role in inducing resistance against drought. A very important and short-term approach in this regard is seed priming which is a pre-sowing hydration of the seed in such a way that the germination metabolism is initiated but the emergence of radicle is avoided (Farooq et al., 2006). Seed priming has proved beneficial in improving the germination metabolism and early stand establishment of crops under normal and stress conditions (Farooq et al., 2007; Bajwa and Farooq, 2016). The priming of the rice seedlings with 5% polyethylene glycol and sodium chloride solutions significantly improved their performance under drought conditions (Goswami et al., 2013). Similarly, a 44% increase in the germination of wheat seeds was also recorded by seed priming under drought conditions (Ajouri et al., 2004). An improved performance of some wheat cultivars was reported under drought conditions after priming with potassium chloride (Eivazi, 2012). Priming of the wheat seeds with ascorbic acid resulted in improved drought resistance due to better accumulation of the proline which helped to maintain the tissue water content and membrane stability (Farooq et al., 2013b). The priming of the maize seeds with putrescine improved the tissue water content and total biomass accumulation under both water limiting and well-watered conditions (Hussain et al., 2013). Khan et al. (2015) reported that the seed priming with calcium chloride played a significant role in improving the performance of maize hybrids under water limiting conditions. A similar improvement in sunflower (Helianthus annuus L.) germination potential, growth and yield was reported by seed priming with potassium nitrate under drought conditions (Kaya et al., 2006). Seed priming with low concentration of allelopathic crop water extracts has also emerged as a beneficial tool to improve crop growth and yield under normal and stressful conditions (Farooq et al., 2013a; Bajwa and Farooq, 2016).

Another important approach for inducing resistance in plant against abiotic stresses is the exogenous application of the growth regulators. The application of the growth regulators helps plants to maintain a fair water balance and chlorophyll content under drought. Foliar applied gibberellic acid improved the stomatal conductance, rate of transpiration, and net photosynthesis in cotton under water limiting conditions (Kumar et al., 2001). Application of jasmonates in combination with brassinolides improved the drought tolerance of maize mainly due to better antioxidant defense (Li et al., 1998). A positive role of the brassinosteroids has been observed in inducing resistance against drought (Rao et al., 2002). Brassinolides were also found useful in improving the germination and seedling growth of the sorghum under water limiting conditions (Vardhini and Rao, 2003). The application of the brassinolides improved the performance of rice under drought and improved the CO₂ assimilation and leaf water economy (Farooq et al., 2009a). Anjum et al. (2011) reported that the exogenous application of the brassinolides improved the performance of maize under drought conditions by improving the water relations and antioxidant defense. Application of salicylic acid improved the drought resistance in wheat by improving the activity of antioxidant enzyme catalase (Horvath et al., 2007). ABA plays an important role in drought stress tolerance and the development of different ABA analogs for ABA receptors have advanced its use in drought stress tolerance (Okamoto et al., 2013).

Exogenous application of osmo-protectants has also been used effectively to improve drought resistance in plants (Ashraf and Foolad, 2007). For instance, the application of glycine betaine can help plants in improving their performance under drought conditions (Hussain et al., 2008). It improves the stomatal conductance, photosynthetic rate, proline accumulation in plants (Ma et al., 2007). Similarly, the application of spermidine has also been fond beneficial in minimizing the harmful effects of drought in barley (Kubis, 2003). Moreover, the application of silicon improved drought tolerance by improving the water uptake in sorghum (Hattori et al., 2005). Other studies have also highlighted the potential of silicon application in improving the drought resistance in major crops including, wheat, rice, and sorghum mainly through improved root growth, stomatal conductance, photosynthetic rate, and antioxidant defense (Lux et al., 1999, 2003; Gong et al., 2005; Hattori et al., 2005).

Relatively less research has been done in resistance induction against heat stress. However, the basic mechanism of using growth regulators, osmo-protectants, and other chemicals is same for drought and heat stress. Preconditioning of plants has proved very effective to combat the heat stress. For instance, preconditioned tomato plants showed better performance under the heat stress by making better osmotic and stomatal adjustments (Morales et al., 2003). Pre-sowing the seeds of pearl millet when exposed to higher temperature (42°C) resulted in better performance (Tikhomirova, 1985). The positive effect of calcium under thermal stress has been reported in certain cool season grasses as it maintains the antioxidant activity (Jiang and Huang, 2001). It has been shown that the exogenous application of calcium can play important role in inducing heat stress resistance in plants by better activity of antioxidant defense (Kolupaev et al., 2005). Wahid and Shabbir (2005) reported that treatment of barley seeds with glycine betaine resulted in better performance under heat stress through improved membrane stability, photosynthetic rate, and leaf water status. Similarly, an improved performance of tomato plants under heat stress was observed by the application of spermidine (Murkowski, 2001).

Further research is needed to explore the potential of seed priming and foliar application of growth regulators in a wide range of crops under heat stress. Moreover, the integrated approaches focusing the use of these techniques with genetic modifications may also be evaluated.