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<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Physiol.</journal-id>
<journal-title>Frontiers in Physiology</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Physiol.</abbrev-journal-title>
<issn pub-type="epub">1664-042X</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
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<article-id pub-id-type="publisher-id">1641580</article-id>
<article-id pub-id-type="doi">10.3389/fphys.2025.1641580</article-id>
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<subj-group subj-group-type="heading">
<subject>Physiology</subject>
<subj-group>
<subject>Retraction</subject>
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<title-group>
<article-title>Retraction: USP22 protects against myocardial ischemia&#x2013;reperfusion injury via the SIRT1-p53/SLC7A11&#x2013;dependent inhibition of ferroptosis&#x2013;induced cardiomyocyte death</article-title>
<alt-title alt-title-type="left-running-head">Frontiers Editorial Office</alt-title>
<alt-title alt-title-type="right-running-head">
<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fphys.2025.1641580">10.3389/fphys.2025.1641580</ext-link>
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<name>
<surname>Frontiers Editorial Office</surname>
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<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/228891/overview"/>
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<p>
<bold>Approved by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/20174/overview">Frontiers Editorial Office</ext-link>, Frontiers Media SA, Switzerland</p>
</fn>
<corresp id="c001">&#x2a;Correspondence: Frontiers Editorial Office, <email>research.integrity@frontiersin.org</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>12</day>
<month>06</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="collection">
<year>2025</year>
</pub-date>
<volume>16</volume>
<elocation-id>1641580</elocation-id>
<history>
<date date-type="received">
<day>05</day>
<month>06</month>
<year>2025</year>
</date>
<date date-type="accepted">
<day>05</day>
<month>06</month>
<year>2025</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2025 Frontiers Editorial Office.</copyright-statement>
<copyright-year>2025</copyright-year>
<copyright-holder>Frontiers Editorial Office</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
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<related-article id="RA1" related-article-type="retracted-article" journal-id="Front. Physiol." journal-id-type="nlm-ta" xlink:href="10.3389/fphys.2020.551318" ext-link-type="doi">A Retraction of the Original Research Article <article-title>USP22 protects against myocardial ischemia&#x2013;reperfusion injury via the SIRT1-p53/SLC7A11&#x2013;dependent inhibition of ferroptosis&#x2013;induced cardiomyocyte death</article-title> by Ma S, Sun L, Wu W, Wu J, Sun Z and Ren J (2020). Front. Physiol. 11:551318. doi: <object-id>10.3389/fphys.2020.551318</object-id>
</related-article>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Vascular Physiology</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<p>The journal retracts the 21 October 2020 article cited above. Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers&#x2019; policies.</p>
<p>This retraction was approved by the Chief Editors of Frontiers of Physiology and the Chief Executive Editor of Frontiers. The authors received a communication regarding the retraction and had a chance to respond. This communication is recorded by the publisher.</p>
</body>
</article>