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<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Phys.</journal-id>
<journal-title>Frontiers in Physics</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Phys.</abbrev-journal-title>
<issn pub-type="epub">2296-424X</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
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<article-meta>
<article-id pub-id-type="publisher-id">1616647</article-id>
<article-id pub-id-type="doi">10.3389/fphy.2025.1616647</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Physics</subject>
<subj-group>
<subject>Brief Research Report</subject>
</subj-group>
</subj-group>
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<title-group>
<article-title>Numerical solutions of the nonlinear Fisher&#x2019;s equation using a one-level meshless method</article-title>
<alt-title alt-title-type="left-running-head">Jiang et al.</alt-title>
<alt-title alt-title-type="right-running-head">
<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fphy.2025.1616647">10.3389/fphy.2025.1616647</ext-link>
</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Jiang</surname>
<given-names>Yingzi</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
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<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Wang</surname>
<given-names>Fuzhang</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/1386064/overview"/>
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<role content-type="https://credit.niso.org/contributor-roles/investigation/"/>
<role content-type="https://credit.niso.org/contributor-roles/methodology/"/>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Sun</surname>
<given-names>Zhongyang</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
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</contrib-group>
<aff id="aff1">
<sup>1</sup>
<institution>Institute of Data Science and Engineering</institution>, <institution>Xuzhou University of Technology</institution>, <addr-line>Xuzhou</addr-line>, <country>China</country>
</aff>
<aff id="aff2">
<sup>2</sup>
<institution>School of Mathematics and Statistics</institution>, <institution>Huaibei Normal University</institution>, <addr-line>Huaibei</addr-line>, <country>China</country>
</aff>
<author-notes>
<fn fn-type="edited-by">
<p>
<bold>Edited by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/1159392/overview">Fei Yu</ext-link>, Changsha University of Science and Technology, China</p>
</fn>
<fn fn-type="edited-by">
<p>
<bold>Reviewed by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/1273399/overview">S&#xed;lvio Gama</ext-link>, University of Porto, Portugal</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/3054930/overview">Wenzhen Qu</ext-link>, Qingdao University, China</p>
</fn>
<corresp id="c001">&#x2a;Correspondence: Fuzhang Wang, <email>wangfuzhang1984@163.com</email>; Zhongyang Sun, <email>sunzhongyang1@163.com</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>24</day>
<month>06</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="collection">
<year>2025</year>
</pub-date>
<volume>13</volume>
<elocation-id>1616647</elocation-id>
<history>
<date date-type="received">
<day>23</day>
<month>04</month>
<year>2025</year>
</date>
<date date-type="accepted">
<day>10</day>
<month>06</month>
<year>2025</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2025 Jiang, Wang and Sun.</copyright-statement>
<copyright-year>2025</copyright-year>
<copyright-holder>Jiang, Wang and Sun</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<p>This study introduces a relatively new numerical technique for solving one-dimensional Fisher&#x2019;s equation. The proposed numerical technique is a simple direct meshless method, which is based on the collocation scheme. To circumvent the traditional two-level numerical procedure, the space-time radial basis function is considered. Under such circumstances, the time-dependent one-dimensional nonlinear Fisher&#x2019;s equation can be solved by a one-level numerical procedure. Several numerical results are investigated to show advantages of the proposed meshless method.</p>
</abstract>
<kwd-group>
<kwd>Fisher&#x2019;s equation</kwd>
<kwd>meshless method</kwd>
<kwd>one-level method</kwd>
<kwd>radial basis function</kwd>
<kwd>numerical simulation</kwd>
</kwd-group>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Interdisciplinary Physics</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec id="s1">
<title>1 Introduction</title>
<p>The application areas of nonlinear fisher&#x2019;s equation include biology [<xref ref-type="bibr" rid="B1">1</xref>], ecology [<xref ref-type="bibr" rid="B2">2</xref>] cancer research [<xref ref-type="bibr" rid="B3">3</xref>], chemistry [<xref ref-type="bibr" rid="B4">4</xref>], etc. It continues to serve the spatiotemporal dynamics modeling of complex systems, and in the future, it will deeply intersect with cutting-edge fields such as quantum computing and synthetic biology. As a classic reaction-diffusion model, the nonlinear fisher&#x2019;s equation has the following form<disp-formula id="e1">
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<mml:mn>0</mml:mn>
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</mml:math>
<label>(1)</label>
</disp-formula>
</p>
<p>Here, <inline-formula id="inf1">
<mml:math id="m2">
<mml:mrow>
<mml:mi>&#x3b1;</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> denotes the constant diffusion coefficient or diffusion factor and <inline-formula id="inf2">
<mml:math id="m3">
<mml:mrow>
<mml:mi>&#x3b3;</mml:mi>
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<p>Numerical simulation of Fisher&#x2019;s equation has made significant progress driven by computational power, algorithm innovation, and interdisciplinary demands [<xref ref-type="bibr" rid="B5">5</xref>]. Traditional methods include the finite difference method [<xref ref-type="bibr" rid="B6">6</xref>], the finite element method [<xref ref-type="bibr" rid="B7">7</xref>], and coupled numerical methods based on traditional methods [<xref ref-type="bibr" rid="B8">8</xref>&#x2013;<xref ref-type="bibr" rid="B10">10</xref>]. By using generalized Hermite interpolation, a fully discrete pseudospectral scheme is presented for Fisher&#x2019;s equation [<xref ref-type="bibr" rid="B11">11</xref>]. Geeta and Varun [<xref ref-type="bibr" rid="B12">12</xref>] investigated trigonometric B-spline collocation method to simulate the 1-D Fisher&#x2019;s equation. A hybrid numerical method [<xref ref-type="bibr" rid="B13">13</xref>], which is composed by cubic trigonometric B-spline base functions and differential quadrature method, is proposed for the numerical solution of Fisher&#x2019;s reaction-diffusion equation. Based on the finite difference method and wavelet Galerkin method, Haifa [<xref ref-type="bibr" rid="B14">14</xref>] proposed an algorithm to simulate the Fisher&#x2019;s equation. The Haar wavelet method is applied to obtain the approximate solution for the Fisher&#x2019;s equations by Sakina et al. [<xref ref-type="bibr" rid="B15">15</xref>]. Based on Barycentric Rational interpolation, Mittal and Rohila [<xref ref-type="bibr" rid="B16">16</xref>] proposed a numerical approach to simulate the Burgers&#x2019; and Fisher&#x2019;s equations.</p>
<p>Since the radial-basis-function-based collocation methods are truly meshless numerical methods, they are widely used in solving partial differential equations and analyzing complex engineering problems. The effectiveness of the BKM is investigated for solving Helmholtz-type problems under various conditions through a series of novel numerical experiments [<xref ref-type="bibr" rid="B17">17</xref>]. Based on the method of fundamental solutions, a high-accuracy and efficient method is provided for addressing antiplane piezoelectricity problems with multiple inclusions [<xref ref-type="bibr" rid="B18">18</xref>]. A new meshfree method is proposed for heat transfer problems in porous material energy storage battery [<xref ref-type="bibr" rid="B19">19</xref>].</p>
<p>Some investigations have been performed by using radial-basis-function-based methods to simulate Fisher&#x2019;s equation. Based on the global radial basis function method, Zhang et al. [<xref ref-type="bibr" rid="B20">20</xref>] proposed a two-level radial basis function-finite difference method for solving nonlinear Fisher&#x2019;s equation. A novel meshless local collocation method is proposed for the numerical solution of the 3-D extended Fisher-Kolmogorov equation [<xref ref-type="bibr" rid="B21">21</xref>]. In combination with the pseudo-spectral method, Geeta et al. [<xref ref-type="bibr" rid="B22">22</xref>] used the radial basis function to get the numerical solution of Fisher&#x2019;s equation. Along with the radial basis functions, particle swarm optimisation algorithm is used to obtain the numerical solutions of the Fisher&#x2019;s equation [<xref ref-type="bibr" rid="B23">23</xref>].</p>
<p>As mentioned in the previous-analysis, there are some investigations related to the meshless method for Fisher&#x2019;s equation. However, these numerical methods are two-level numerical methods. The meshless method should be accompanied with the other numerical methods to deal with time-dependent term in the governing equation. To seek for an alternative way, we propose a one-level meshless method for Fisher&#x2019;s equation. By using a space-time formulation, the time-dependent term can be treated as space-dependent term. The initial and boundary conditions for Fisher&#x2019;s equation are given as<disp-formula id="e2">
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<p>The rest of this paper is organized as follows. <xref ref-type="sec" rid="s2">Section 2</xref> provides a brief description of the one-level meshless method. Numerical examples are provided in <xref ref-type="sec" rid="s3">Section 3</xref> and some concluding remarks are given in <xref ref-type="sec" rid="s4">Section 4</xref>.</p>
</sec>
<sec id="s2">
<title>2 The one-level meshless methods</title>
<p>As is known to all, the time-dependent problems <xref ref-type="disp-formula" rid="e1">Equations 1</xref>, <xref ref-type="disp-formula" rid="e2">2</xref> are always solved by using two-level numerical methods. The finite difference scheme or integral transform method should be employed to deal with the time-dependent term, and the resulting elliptic-type problems are solved by the other numerical methods. There are two aspects in the accumulation of errors of two-level methods, i.e., the finite difference step and the numerical method step.</p>
<p>To find an alternative to the two-level method, a one-level direct meshless method is proposed in this section. The one-level direct meshless method is based on space-time radial basis functions (RBFs). Under such one-level meshless method, there&#x2019;s only one aspect in the accumulation of errors.</p>
<sec id="s2-1">
<title>2.1 The space-time RBFs</title>
<p>RBFs are a type of scalar function based on distance measurement, whose core characteristic is that the function value only depends on the distance from the two points. The advantages of RBFs include local response characteristics, efficient processing of sparse or high-dimensional data, simple mathematical form, easy-to-implement, and parallel computing.</p>
<p>For 2D steady-state problems, the commonly-used RBFs include three types, the detailed formula is shown in <xref ref-type="disp-formula" rid="e3">Equation 3</xref>
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</inline-formula> is the Euclidean distance between two points <inline-formula id="inf6">
<mml:math id="m9">
<mml:mrow>
<mml:msub>
<mml:mi>X</mml:mi>
<mml:mi>i</mml:mi>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mi>i</mml:mi>
</mml:msub>
<mml:mo>,</mml:mo>
<mml:msub>
<mml:mi>y</mml:mi>
<mml:mi>i</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:math>
</inline-formula> and <inline-formula id="inf7">
<mml:math id="m10">
<mml:mrow>
<mml:msub>
<mml:mi>X</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mo>,</mml:mo>
<mml:msub>
<mml:mi>y</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:math>
</inline-formula>, <inline-formula id="inf8">
<mml:math id="m11">
<mml:mrow>
<mml:mi>&#x3b5;</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> is the RBF shape parameter.</p>
<p>Since there is only one space variable in Fisher&#x2019;s <xref ref-type="disp-formula" rid="e1">Equation 1</xref>, we consider the time variable &#x201c;equally&#x201d; as a new space variable. More specifically, the Fisher&#x2019;s equation is considered as a &#x201c;equally&#x201d; steady-state equation. The corresponding space-time RBFs has the form<disp-formula id="e4">
<mml:math id="m12">
<mml:mrow>
<mml:mi>&#x3d5;</mml:mi>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mover accent="true">
<mml:mi>r</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>&#x3d;</mml:mo>
<mml:mrow>
<mml:mfenced open="{" close="" separators="|">
<mml:mrow>
<mml:mtable columnalign="left">
<mml:mtr>
<mml:mtd>
<mml:mrow>
<mml:msqrt>
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>&#x3b5;</mml:mi>
<mml:mover accent="true">
<mml:mi>r</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:msqrt>
<mml:mo>,</mml:mo>
<mml:mtext>Multiquadric</mml:mtext>
<mml:mo>,</mml:mo>
</mml:mrow>
</mml:mtd>
</mml:mtr>
<mml:mtr>
<mml:mtd>
<mml:mrow>
<mml:msup>
<mml:mi>e</mml:mi>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>&#x3b5;</mml:mi>
<mml:mover accent="true">
<mml:mi>r</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:msup>
<mml:mo>,</mml:mo>
<mml:mtext>Gaussian</mml:mtext>
<mml:mo>,</mml:mo>
</mml:mrow>
</mml:mtd>
</mml:mtr>
<mml:mtr>
<mml:mtd>
<mml:mrow>
<mml:msup>
<mml:mover accent="true">
<mml:mi>r</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:mo>&#x2061;</mml:mo>
<mml:mi>log</mml:mi>
<mml:mover accent="true">
<mml:mi>r</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mo>,</mml:mo>
<mml:mtext>Thin&#x2002;Plate&#x2002;Spline</mml:mtext>
<mml:mo>.</mml:mo>
</mml:mrow>
</mml:mtd>
</mml:mtr>
</mml:mtable>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:math>
<label>(4)</label>
</disp-formula>
</p>
<p>Here, <inline-formula id="inf9">
<mml:math id="m13">
<mml:mrow>
<mml:mover accent="true">
<mml:mi>r</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mo>&#x3d;</mml:mo>
<mml:msqrt>
<mml:mrow>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mi>i</mml:mi>
</mml:msub>
<mml:mo>&#x2212;</mml:mo>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:msub>
<mml:mi>t</mml:mi>
<mml:mi>i</mml:mi>
</mml:msub>
<mml:mo>&#x2212;</mml:mo>
<mml:msub>
<mml:mi>t</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:msqrt>
</mml:mrow>
</mml:math>
</inline-formula> is the Euclidean distance between two space-time points <inline-formula id="inf10">
<mml:math id="m14">
<mml:mrow>
<mml:msub>
<mml:mover accent="true">
<mml:mi>X</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>i</mml:mi>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mi>i</mml:mi>
</mml:msub>
<mml:mo>,</mml:mo>
<mml:msub>
<mml:mi>t</mml:mi>
<mml:mi>i</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:math>
</inline-formula> and <inline-formula id="inf11">
<mml:math id="m15">
<mml:mrow>
<mml:msub>
<mml:mover accent="true">
<mml:mi>X</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mo>,</mml:mo>
<mml:msub>
<mml:mi>t</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:math>
</inline-formula>.</p>
</sec>
<sec id="s2-2">
<title>2.2 Implementation of the one-level meshless method</title>
<p>Before implementation of the one-level meshless method, collocation points should be provided. More specifically, the space variable interval <inline-formula id="inf12">
<mml:math id="m16">
<mml:mrow>
<mml:mfenced open="[" close="]" separators="|">
<mml:mrow>
<mml:mi>a</mml:mi>
<mml:mo>,</mml:mo>
<mml:mi>b</mml:mi>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:math>
</inline-formula> is divided into small segments <inline-formula id="inf13">
<mml:math id="m17">
<mml:mrow>
<mml:mi>a</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mn>0</mml:mn>
</mml:msub>
<mml:mo>&#x3c;</mml:mo>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mn>1</mml:mn>
</mml:msub>
<mml:mo>&#x3c;</mml:mo>
<mml:mo>.</mml:mo>
<mml:mo>.</mml:mo>
<mml:mo>.</mml:mo>
<mml:mo>&#x3c;</mml:mo>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mi>n</mml:mi>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:mi>b</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> and the time variable interval <inline-formula id="inf14">
<mml:math id="m18">
<mml:mrow>
<mml:mfenced open="[" close="]" separators="|">
<mml:mrow>
<mml:mn>0</mml:mn>
<mml:mo>,</mml:mo>
<mml:mi>T</mml:mi>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:math>
</inline-formula> is divided into segments <inline-formula id="inf15">
<mml:math id="m19">
<mml:mrow>
<mml:mn>0</mml:mn>
<mml:mo>&#x3d;</mml:mo>
<mml:msub>
<mml:mi>t</mml:mi>
<mml:mn>0</mml:mn>
</mml:msub>
<mml:mo>&#x3c;</mml:mo>
<mml:msub>
<mml:mi>t</mml:mi>
<mml:mn>1</mml:mn>
</mml:msub>
<mml:mo>&#x3c;</mml:mo>
<mml:mo>.</mml:mo>
<mml:mo>.</mml:mo>
<mml:mo>.</mml:mo>
<mml:mo>&#x3c;</mml:mo>
<mml:msub>
<mml:mi>t</mml:mi>
<mml:mi>n</mml:mi>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:mi>T</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula>. The interval division is usually under uniform scheme, but it is also workable for un-uniform scheme.</p>
<p>According to the basic theory of collocation methods, the approximate solution of the function <inline-formula id="inf16">
<mml:math id="m20">
<mml:mrow>
<mml:mi>u</mml:mi>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:math>
</inline-formula> at an arbitrary point <inline-formula id="inf17">
<mml:math id="m21">
<mml:mrow>
<mml:mover accent="true">
<mml:mi>X</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mo>&#x3d;</mml:mo>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:math>
</inline-formula> in Fisher&#x2019;s equation has the form<disp-formula id="e5">
<mml:math id="m22">
<mml:mrow>
<mml:mover accent="true">
<mml:mi>u</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mo>&#xb7;</mml:mo>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>&#x2248;</mml:mo>
<mml:mrow>
<mml:mstyle displaystyle="true">
<mml:munderover>
<mml:mo>&#x2211;</mml:mo>
<mml:mrow>
<mml:mi>j</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mi>N</mml:mi>
</mml:munderover>
</mml:mstyle>
<mml:mrow>
<mml:msub>
<mml:mi>&#x3bb;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mo>&#xb7;</mml:mo>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:mrow>
</mml:mrow>
</mml:math>
<label>(5)</label>
</disp-formula>with <inline-formula id="inf18">
<mml:math id="m23">
<mml:mrow>
<mml:msubsup>
<mml:mrow>
<mml:mfenced open="{" close="}" separators="|">
<mml:mrow>
<mml:msub>
<mml:mi>&#x3bb;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mrow>
<mml:mi>j</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mi>N</mml:mi>
</mml:msubsup>
</mml:mrow>
</mml:math>
</inline-formula> the unknown coefficients and <inline-formula id="inf19">
<mml:math id="m24">
<mml:mrow>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mo>&#xb7;</mml:mo>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>&#x3d;</mml:mo>
<mml:msqrt>
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>&#x3b5;</mml:mi>
<mml:msub>
<mml:mover accent="true">
<mml:mi>r</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:msqrt>
<mml:mo>&#x3d;</mml:mo>
<mml:msqrt>
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mi>&#x3b5;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mo>&#x2212;</mml:mo>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mi>&#x3b5;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>t</mml:mi>
<mml:mo>&#x2212;</mml:mo>
<mml:msub>
<mml:mi>t</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:msqrt>
</mml:mrow>
</mml:math>
</inline-formula>, where <inline-formula id="inf20">
<mml:math id="m25">
<mml:mrow>
<mml:mi>j</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> is the index of collocation points and <inline-formula id="inf21">
<mml:math id="m26">
<mml:mrow>
<mml:mi>N</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> is the total collocation point number.</p>
<p>To illustrate the one-level meshless method, we substitute <xref ref-type="disp-formula" rid="e6">Equation 6</xref> into <xref ref-type="disp-formula" rid="e1">Equations 1</xref>, <xref ref-type="disp-formula" rid="e2">2</xref> at space-time points <inline-formula id="inf22">
<mml:math id="m27">
<mml:mrow>
<mml:msubsup>
<mml:mrow>
<mml:mfenced open="{" close="}" separators="|">
<mml:mrow>
<mml:msub>
<mml:mover accent="true">
<mml:mi>X</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>k</mml:mi>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mi>k</mml:mi>
</mml:msub>
<mml:mo>,</mml:mo>
<mml:msub>
<mml:mi>t</mml:mi>
<mml:mi>k</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mrow>
<mml:mi>k</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mi>n</mml:mi>
<mml:mo>&#xd7;</mml:mo>
<mml:mi>n</mml:mi>
</mml:mrow>
</mml:msubsup>
</mml:mrow>
</mml:math>
</inline-formula>. Then, one can obtain the following equations<disp-formula id="e6">
<mml:math id="m28">
<mml:mrow>
<mml:mrow>
<mml:mstyle displaystyle="true">
<mml:munderover>
<mml:mo>&#x2211;</mml:mo>
<mml:mrow>
<mml:mi>j</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mi>N</mml:mi>
</mml:munderover>
</mml:mstyle>
<mml:mrow>
<mml:msub>
<mml:mi>&#x3bb;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mi mathvariant="script">L</mml:mi>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:msub>
<mml:mover accent="true">
<mml:mi>X</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>k</mml:mi>
</mml:msub>
<mml:mo>,</mml:mo>
<mml:msub>
<mml:mover accent="true">
<mml:mi>X</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:mrow>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>0</mml:mn>
<mml:mo>,</mml:mo>
<mml:mi>k</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
<mml:mo>,</mml:mo>
<mml:mo>.</mml:mo>
<mml:mo>.</mml:mo>
<mml:mo>.</mml:mo>
<mml:mo>,</mml:mo>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>n</mml:mi>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:mo>,</mml:mo>
</mml:mrow>
</mml:math>
<label>(6)</label>
</disp-formula>
<disp-formula id="e7">
<mml:math id="m29">
<mml:mrow>
<mml:mrow>
<mml:mfenced open="{" close="" separators="|">
<mml:mrow>
<mml:mtable columnalign="left">
<mml:mtr>
<mml:mtd>
<mml:mrow>
<mml:mrow>
<mml:mstyle displaystyle="true">
<mml:munderover>
<mml:mo>&#x2211;</mml:mo>
<mml:mrow>
<mml:mi>j</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mi>N</mml:mi>
</mml:munderover>
</mml:mstyle>
<mml:mrow>
<mml:msub>
<mml:mi>&#x3bb;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:msub>
<mml:mover accent="true">
<mml:mi>X</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>k</mml:mi>
</mml:msub>
<mml:mo>,</mml:mo>
<mml:msub>
<mml:mover accent="true">
<mml:mi>X</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:mrow>
<mml:mo>&#x3d;</mml:mo>
<mml:msub>
<mml:mi>u</mml:mi>
<mml:mn>0</mml:mn>
</mml:msub>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:msub>
<mml:mover accent="true">
<mml:mi>X</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>k</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>,</mml:mo>
</mml:mrow>
</mml:mtd>
</mml:mtr>
<mml:mtr>
<mml:mtd>
<mml:mrow>
<mml:mrow>
<mml:mstyle displaystyle="true">
<mml:munderover>
<mml:mo>&#x2211;</mml:mo>
<mml:mrow>
<mml:mi>j</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mi>N</mml:mi>
</mml:munderover>
</mml:mstyle>
<mml:mrow>
<mml:msub>
<mml:mi>&#x3bb;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:msub>
<mml:mover accent="true">
<mml:mi>X</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>k</mml:mi>
</mml:msub>
<mml:mo>,</mml:mo>
<mml:msub>
<mml:mover accent="true">
<mml:mi>X</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:mrow>
<mml:mo>&#x3d;</mml:mo>
<mml:mover accent="true">
<mml:mi>u</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:msub>
<mml:mover accent="true">
<mml:mi>X</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>k</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>,</mml:mo>
</mml:mrow>
</mml:mtd>
</mml:mtr>
</mml:mtable>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mi>k</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>n</mml:mi>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:mo>&#x2b;</mml:mo>
<mml:mn>1</mml:mn>
<mml:mo>,</mml:mo>
<mml:mo>.</mml:mo>
<mml:mo>.</mml:mo>
<mml:mo>.</mml:mo>
<mml:mo>,</mml:mo>
<mml:msup>
<mml:mi>n</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:mo>.</mml:mo>
</mml:mrow>
</mml:math>
<label>(7)</label>
</disp-formula>
</p>
<p>Here, the operator is shown in the following <xref ref-type="disp-formula" rid="e8">Equation 8</xref>
<disp-formula id="e8">
<mml:math id="m30">
<mml:mrow>
<mml:mi mathvariant="script">L</mml:mi>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:mi>&#x3b1;</mml:mi>
<mml:mfrac>
<mml:mrow>
<mml:msup>
<mml:mi mathvariant="normal">&#x2202;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
<mml:mrow>
<mml:mi mathvariant="normal">&#x2202;</mml:mi>
<mml:msup>
<mml:mi>x</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:mfrac>
<mml:mo>&#x2212;</mml:mo>
<mml:mfrac>
<mml:mrow>
<mml:mi mathvariant="normal">&#x2202;</mml:mi>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
<mml:mrow>
<mml:mi mathvariant="normal">&#x2202;</mml:mi>
<mml:mi>t</mml:mi>
</mml:mrow>
</mml:mfrac>
<mml:mo>&#x2b;</mml:mo>
<mml:mi>&#x3b3;</mml:mi>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2212;</mml:mo>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>.</mml:mo>
</mml:mrow>
</mml:math>
<label>(8)</label>
</disp-formula>
</p>
<p>For multiquadric RBF <inline-formula id="inf23">
<mml:math id="m31">
<mml:mrow>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>r</mml:mi>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>&#x3d;</mml:mo>
<mml:msqrt>
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>&#x3b5;</mml:mi>
<mml:msub>
<mml:mover accent="true">
<mml:mi>r</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:msqrt>
<mml:mo>&#x3d;</mml:mo>
</mml:mrow>
</mml:math>
</inline-formula> <inline-formula id="inf123">
<mml:math id="m131">
<mml:mrow>
<mml:msqrt>
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mi>&#x3b5;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mo>&#x2212;</mml:mo>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mi>&#x3b5;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>t</mml:mi>
<mml:mo>&#x2212;</mml:mo>
<mml:msub>
<mml:mi>t</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:msqrt>
</mml:mrow>
</mml:math>
</inline-formula>, we have the corresponding derivatives in <xref ref-type="disp-formula" rid="e9">Equations 9</xref>&#x2013;<xref ref-type="disp-formula" rid="e11">11</xref>
<disp-formula id="e9">
<mml:math id="m32">
<mml:mrow>
<mml:mfrac>
<mml:mrow>
<mml:mi mathvariant="normal">&#x2202;</mml:mi>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
<mml:mrow>
<mml:mi mathvariant="normal">&#x2202;</mml:mi>
<mml:mi>x</mml:mi>
</mml:mrow>
</mml:mfrac>
<mml:mo>&#x3d;</mml:mo>
<mml:msup>
<mml:mi>&#x3b5;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mo>&#x2212;</mml:mo>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mi>&#x3b5;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:msubsup>
<mml:mover accent="true">
<mml:mi>r</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>j</mml:mi>
<mml:mn>2</mml:mn>
</mml:msubsup>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mfrac>
<mml:mrow>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:mfrac>
</mml:mrow>
</mml:msup>
<mml:mo>,</mml:mo>
</mml:mrow>
</mml:math>
<label>(9)</label>
</disp-formula>
<disp-formula id="e10">
<mml:math id="m33">
<mml:mrow>
<mml:mfrac>
<mml:mrow>
<mml:msup>
<mml:mi mathvariant="normal">&#x2202;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
<mml:mrow>
<mml:mi mathvariant="normal">&#x2202;</mml:mi>
<mml:msup>
<mml:mi>x</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:mfrac>
<mml:mo>&#x3d;</mml:mo>
<mml:msup>
<mml:mi>&#x3b5;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mi>&#x3b5;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:msubsup>
<mml:mover accent="true">
<mml:mi>r</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>j</mml:mi>
<mml:mn>2</mml:mn>
</mml:msubsup>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mfrac>
<mml:mrow>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:mfrac>
</mml:mrow>
</mml:msup>
<mml:mrow>
<mml:mfenced open="[" close="]" separators="|">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2212;</mml:mo>
<mml:msup>
<mml:mi>&#x3b5;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mo>&#x2212;</mml:mo>
<mml:msub>
<mml:mi>x</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:mo>/</mml:mo>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mi>&#x3b5;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:msubsup>
<mml:mover accent="true">
<mml:mi>r</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>j</mml:mi>
<mml:mn>2</mml:mn>
</mml:msubsup>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>,</mml:mo>
</mml:mrow>
</mml:math>
<label>(10)</label>
</disp-formula>
<disp-formula id="e11">
<mml:math id="m34">
<mml:mrow>
<mml:mfrac>
<mml:mrow>
<mml:mi mathvariant="normal">&#x2202;</mml:mi>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
<mml:mrow>
<mml:mi mathvariant="normal">&#x2202;</mml:mi>
<mml:mi>t</mml:mi>
</mml:mrow>
</mml:mfrac>
<mml:mo>&#x3d;</mml:mo>
<mml:msup>
<mml:mi>&#x3b5;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>t</mml:mi>
<mml:mo>&#x2212;</mml:mo>
<mml:msub>
<mml:mi>t</mml:mi>
<mml:mi>j</mml:mi>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mi>&#x3b5;</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
<mml:msubsup>
<mml:mover accent="true">
<mml:mi>r</mml:mi>
<mml:mo>&#xaf;</mml:mo>
</mml:mover>
<mml:mi>j</mml:mi>
<mml:mn>2</mml:mn>
</mml:msubsup>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mfrac>
<mml:mrow>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:mfrac>
</mml:mrow>
</mml:msup>
<mml:mo>.</mml:mo>
</mml:mrow>
</mml:math>
<label>(11)</label>
</disp-formula>
</p>
<p>In order to obtain a square interpolation matrix, we consider <inline-formula id="inf24">
<mml:math id="m35">
<mml:mrow>
<mml:mi>N</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mi>n</mml:mi>
<mml:mo>&#xd7;</mml:mo>
<mml:mi>n</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula>. <xref ref-type="disp-formula" rid="e6">Equations 6</xref>, <xref ref-type="disp-formula" rid="e7">7</xref> has the matrix form as shown in <xref ref-type="disp-formula" rid="e12">Equation 12</xref>
<disp-formula id="e12">
<mml:math id="m36">
<mml:mrow>
<mml:mi mathvariant="bold">A</mml:mi>
<mml:mi>&#x3bb;</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mi mathvariant="bold">f</mml:mi>
<mml:mo>,</mml:mo>
</mml:mrow>
</mml:math>
<label>(12)</label>
</disp-formula>where <inline-formula id="inf25">
<mml:math id="m37">
<mml:mrow>
<mml:mi mathvariant="bold">A</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mrow>
<mml:mfenced open="[" close="]" separators="|">
<mml:mrow>
<mml:msub>
<mml:mi>&#x3d5;</mml:mi>
<mml:mrow>
<mml:mi>k</mml:mi>
<mml:mi>j</mml:mi>
</mml:mrow>
</mml:msub>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:math>
</inline-formula> is <inline-formula id="inf26">
<mml:math id="m38">
<mml:mrow>
<mml:mi>N</mml:mi>
<mml:mo>&#xd7;</mml:mo>
<mml:mi>N</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> interpolation matrix, <inline-formula id="inf27">
<mml:math id="m39">
<mml:mrow>
<mml:mi>&#x3bb;</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> and <inline-formula id="inf28">
<mml:math id="m40">
<mml:mrow>
<mml:mi mathvariant="bold">f</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula> are <inline-formula id="inf29">
<mml:math id="m41">
<mml:mrow>
<mml:mi>N</mml:mi>
<mml:mo>&#xd7;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> vectors.</p>
<p>
<xref ref-type="disp-formula" rid="e9">Equation 9</xref> can be directly solved to get the unknowns <inline-formula id="inf30">
<mml:math id="m42">
<mml:mrow>
<mml:mi>&#x3bb;</mml:mi>
</mml:mrow>
</mml:math>
</inline-formula>. Then the approximation solution of the unknown function in the Fisher&#x2019;s equation can be solved by using <xref ref-type="disp-formula" rid="e5">Equation 5</xref>.</p>
</sec>
</sec>
<sec id="s3">
<title>3 Numerical simulations</title>
<p>In the following numerical examples, the multiquadrics RBF in <xref ref-type="disp-formula" rid="e4">Equation 4</xref> is used to illustrate the numerical results. We use the <inline-formula id="inf31">
<mml:math id="m43">
<mml:mrow>
<mml:msub>
<mml:mi>L</mml:mi>
<mml:mn>2</mml:mn>
</mml:msub>
<mml:mo>&#x2212;</mml:mo>
<mml:mtext>error</mml:mtext>
</mml:mrow>
</mml:math>
</inline-formula> to show the accuracy of the proposed method. The <inline-formula id="inf32">
<mml:math id="m44">
<mml:mrow>
<mml:msub>
<mml:mi>L</mml:mi>
<mml:mn>2</mml:mn>
</mml:msub>
<mml:mo>&#x2212;</mml:mo>
<mml:mtext>error</mml:mtext>
</mml:mrow>
</mml:math>
</inline-formula> of the proposed method is also compared with the results in previous literatures. The optimal choice of RBF parameter has been investigated in many literatures [<xref ref-type="bibr" rid="B24">24</xref>, <xref ref-type="bibr" rid="B25">25</xref>]. This is beyond the scope of our current research, we use the simple prior-tested selection of the shape parameter in all numerical results [<xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B27">27</xref>]. Due to the limitation of the paper type, the initial condition plots are provided in the appendix.</p>
<sec id="s3-1">
<title>3.1 Example 1</title>
<p>For the constant diffusion coefficient <inline-formula id="inf33">
<mml:math id="m45">
<mml:mrow>
<mml:mi>&#x3b1;</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> and the reaction factor <inline-formula id="inf34">
<mml:math id="m46">
<mml:mrow>
<mml:mi>&#x3b3;</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>6</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>, the fisher&#x2019;s equation has the form in <xref ref-type="disp-formula" rid="e13">Equation 13</xref>
<disp-formula id="e13">
<mml:math id="m47">
<mml:mrow>
<mml:msub>
<mml:mi>u</mml:mi>
<mml:mi>t</mml:mi>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:msub>
<mml:mi>u</mml:mi>
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mi>x</mml:mi>
</mml:mrow>
</mml:msub>
<mml:mo>&#x2b;</mml:mo>
<mml:mn>6</mml:mn>
<mml:mi>u</mml:mi>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2212;</mml:mo>
<mml:mi>u</mml:mi>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>,</mml:mo>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>1</mml:mn>
<mml:mo>&#x3c;</mml:mo>
<mml:mi>x</mml:mi>
<mml:mo>&#x3c;</mml:mo>
<mml:mn>1</mml:mn>
<mml:mo>,</mml:mo>
<mml:mn>0</mml:mn>
<mml:mo>&#x3c;</mml:mo>
<mml:mi>t</mml:mi>
<mml:mo>&#x3c;</mml:mo>
<mml:mi>T</mml:mi>
<mml:mo>.</mml:mo>
</mml:mrow>
</mml:math>
<label>(13)</label>
</disp-formula>
</p>
<p>The corresponding exact solution is<disp-formula id="e14">
<mml:math id="m48">
<mml:mrow>
<mml:mi>u</mml:mi>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>&#x3d;</mml:mo>
<mml:mfrac>
<mml:mrow>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:msup>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2b;</mml:mo>
<mml:msup>
<mml:mi>e</mml:mi>
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>5</mml:mn>
<mml:mi>t</mml:mi>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:mfrac>
<mml:mo>.</mml:mo>
</mml:mrow>
</mml:math>
<label>(14)</label>
</disp-formula>
</p>
<p>The corresponding initial condition and boundary condition can be deduced from <xref ref-type="disp-formula" rid="e14">Equation 14</xref>.</p>
<p>At time <inline-formula id="inf35">
<mml:math id="m49">
<mml:mrow>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>, the variation of shape parameter versus the <inline-formula id="inf36">
<mml:math id="m50">
<mml:mrow>
<mml:msub>
<mml:mi>L</mml:mi>
<mml:mn>2</mml:mn>
</mml:msub>
<mml:mo>&#x2212;</mml:mo>
<mml:mtext>error</mml:mtext>
</mml:mrow>
</mml:math>
</inline-formula> is presented in <xref ref-type="fig" rid="F1">Figure 1</xref> for fixed collocation point number <inline-formula id="inf37">
<mml:math id="m51">
<mml:mrow>
<mml:mi>N</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>117</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>. It can be seen that the quasi-optimal <inline-formula id="inf38">
<mml:math id="m52">
<mml:mrow>
<mml:msub>
<mml:mi>L</mml:mi>
<mml:mn>2</mml:mn>
</mml:msub>
<mml:mo>&#x2212;</mml:mo>
<mml:mtext>error</mml:mtext>
</mml:mrow>
</mml:math>
</inline-formula> is <inline-formula id="inf39">
<mml:math id="m53">
<mml:mrow>
<mml:mn>6.8893</mml:mn>
<mml:mo>&#xd7;</mml:mo>
<mml:msup>
<mml:mn>10</mml:mn>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>8</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> for shape parameter <inline-formula id="inf40">
<mml:math id="m54">
<mml:mrow>
<mml:mi>&#x3b5;</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1.45</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>. This is more accurate than the most accurate numerical result <inline-formula id="inf41">
<mml:math id="m55">
<mml:mrow>
<mml:mn>4.33</mml:mn>
<mml:mo>&#xd7;</mml:mo>
<mml:msup>
<mml:mn>10</mml:mn>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>5</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> in [<xref ref-type="bibr" rid="B14">14</xref>]. For shape parameter <inline-formula id="inf42">
<mml:math id="m56">
<mml:mrow>
<mml:mi>&#x3b5;</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1.45</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>, <xref ref-type="fig" rid="F2">Figure 2</xref> is plotted to show that the numerical solution is highly consistent with the analytical solution.</p>
<fig id="F1" position="float">
<label>FIGURE 1</label>
<caption>
<p>
<inline-formula id="inf43">
<mml:math id="m57">
<mml:mrow>
<mml:msub>
<mml:mi>L</mml:mi>
<mml:mn>2</mml:mn>
</mml:msub>
<mml:mo>&#x2212;</mml:mo>
<mml:mtext>error</mml:mtext>
</mml:mrow>
</mml:math>
</inline-formula> curve versus shape parameter.</p>
</caption>
<graphic xlink:href="fphy-13-1616647-g001.tif">
<alt-text content-type="machine-generated">Graph depicting the relationship between the shape parameter and L2 error. The L2 error decreases significantly near a shape parameter of 1.45, reaching approximately 6.8893e-08. Data points fluctuate, showing varying error levels.</alt-text>
</graphic>
</fig>
<fig id="F2" position="float">
<label>FIGURE 2</label>
<caption>
<p>Numerical solution and analytical solution at time <inline-formula id="inf44">
<mml:math id="m58">
<mml:mrow>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>.</p>
</caption>
<graphic xlink:href="fphy-13-1616647-g002.tif">
<alt-text content-type="machine-generated">Graph comparing analytical and numerical solutions for \( u(x,1) \) as a function of \( x \). The plot shows analytical solutions with blue stars and numerical solutions with red dots, both depicting a decreasing trend from 0.995 at \( x = -1 \) to 0.96 at \( x = 1 \).</alt-text>
</graphic>
</fig>
</sec>
<sec id="s3-2">
<title>3.2 Example 2</title>
<p>Here, we consider the following Fisher&#x2019;s equation as shown in <xref ref-type="disp-formula" rid="e15">Equation 15</xref>
<disp-formula id="e15">
<mml:math id="m59">
<mml:mrow>
<mml:msub>
<mml:mi>u</mml:mi>
<mml:mi>t</mml:mi>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:msub>
<mml:mi>u</mml:mi>
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mi>x</mml:mi>
</mml:mrow>
</mml:msub>
<mml:mo>&#x2b;</mml:mo>
<mml:mi>u</mml:mi>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2212;</mml:mo>
<mml:msup>
<mml:mi>u</mml:mi>
<mml:mn>6</mml:mn>
</mml:msup>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>,</mml:mo>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>1</mml:mn>
<mml:mo>&#x3c;</mml:mo>
<mml:mi>x</mml:mi>
<mml:mo>&#x3c;</mml:mo>
<mml:mn>1</mml:mn>
<mml:mo>,</mml:mo>
<mml:mn>0</mml:mn>
<mml:mo>&#x3c;</mml:mo>
<mml:mi>t</mml:mi>
<mml:mo>&#x3c;</mml:mo>
<mml:mi>T</mml:mi>
</mml:mrow>
</mml:math>
<label>(15)</label>
</disp-formula>
</p>
<p>The corresponding exact solution is shown in <xref ref-type="disp-formula" rid="e16">Equation 16</xref>
<disp-formula id="e16">
<mml:math id="m60">
<mml:mrow>
<mml:mi>u</mml:mi>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>&#x3d;</mml:mo> <mml:msup>
<mml:mrow>
<mml:mspace width="0.1em"/>
</mml:mrow>
<mml:mrow>
<mml:mn>3</mml:mn>
</mml:mrow>
</mml:msup>
<mml:mspace width="-0.60em"/>
<mml:msqrt>
<mml:mrow>
<mml:mfrac>
<mml:mrow>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:mfrac>
<mml:mi>tanh</mml:mi>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mfrac>
<mml:mrow>
<mml:mn>3</mml:mn>
<mml:mi>x</mml:mi>
</mml:mrow>
<mml:mn>4</mml:mn>
</mml:mfrac>
<mml:mo>&#x2b;</mml:mo>
<mml:mfrac>
<mml:mrow>
<mml:mn>15</mml:mn>
<mml:mi>t</mml:mi>
</mml:mrow>
<mml:mn>8</mml:mn>
</mml:mfrac>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>&#x2b;</mml:mo>
<mml:mfrac>
<mml:mrow>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:mfrac>
</mml:mrow>
</mml:msqrt>
<mml:mo>.</mml:mo>
</mml:mrow>
</mml:math>
<label>(16)</label>
</disp-formula>
</p>
<p>The quasi-optimal choice of shape parameter is the same as Example 4.1. For shape parameter <inline-formula id="inf45">
<mml:math id="m61">
<mml:mrow>
<mml:mi>&#x3b5;</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>0.44</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>, the <inline-formula id="inf46">
<mml:math id="m62">
<mml:mrow>
<mml:msub>
<mml:mi>L</mml:mi>
<mml:mn>2</mml:mn>
</mml:msub>
<mml:mo>&#x2212;</mml:mo>
<mml:mtext>error</mml:mtext>
</mml:mrow>
</mml:math>
</inline-formula> is <inline-formula id="inf47">
<mml:math id="m63">
<mml:mrow>
<mml:mn>2.8366</mml:mn>
<mml:mo>&#xd7;</mml:mo>
<mml:msup>
<mml:mn>10</mml:mn>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>10</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> at time <inline-formula id="inf48">
<mml:math id="m64">
<mml:mrow>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>, which is also far more accurate than the most accurate result <inline-formula id="inf49">
<mml:math id="m65">
<mml:mrow>
<mml:mn>1.27</mml:mn>
<mml:mo>&#xd7;</mml:mo>
<mml:msup>
<mml:mn>10</mml:mn>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>5</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> in [<xref ref-type="bibr" rid="B14">14</xref>]. <xref ref-type="fig" rid="F3">Figure 3</xref> is plotted to show that the numerical solution is highly consistent with the analytical solution at three different times <inline-formula id="inf50">
<mml:math id="m66">
<mml:mrow>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>0.1</mml:mn>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>0.5</mml:mn>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>.</p>
<fig id="F3" position="float">
<label>FIGURE 3</label>
<caption>
<p>Numerical solution and analytical solution at times <inline-formula id="inf51">
<mml:math id="m67">
<mml:mrow>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>0.1</mml:mn>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>0.5</mml:mn>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>.</p>
</caption>
<graphic xlink:href="fphy-13-1616647-g003.tif">
<alt-text content-type="machine-generated">Line graph depicting the function \( u(x,t) \) over the range \( x = -1 \) to \( x = 1 \). It includes analytical and numerical solutions at times \( t = 1 \), \( t = 0.5 \), and \( t = 0.1 \). Each solution type and time is represented by distinct markers. The graph shows a general downward trend as \( x \) increases.</alt-text>
</graphic>
</fig>
</sec>
<sec id="s3-3">
<title>3.3 Example 3</title>
<p>In this example, we consider the following Fisher&#x2019;s equation as shown in <xref ref-type="disp-formula" rid="e17">Equation 17</xref>
<disp-formula id="e17">
<mml:math id="m68">
<mml:mrow>
<mml:msub>
<mml:mi>u</mml:mi>
<mml:mi>t</mml:mi>
</mml:msub>
<mml:mo>&#x3d;</mml:mo>
<mml:msub>
<mml:mi>u</mml:mi>
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mi>x</mml:mi>
</mml:mrow>
</mml:msub>
<mml:mo>&#x2b;</mml:mo>
<mml:mi>u</mml:mi>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mn>1</mml:mn>
<mml:mo>&#x2212;</mml:mo>
<mml:msup>
<mml:mi>u</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>,</mml:mo>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>1</mml:mn>
<mml:mo>&#x3c;</mml:mo>
<mml:mi>x</mml:mi>
<mml:mo>&#x3c;</mml:mo>
<mml:mn>1</mml:mn>
<mml:mo>,</mml:mo>
<mml:mn>0</mml:mn>
<mml:mo>&#x3c;</mml:mo>
<mml:mi>t</mml:mi>
<mml:mo>&#x3c;</mml:mo>
<mml:mi>T</mml:mi>
<mml:mo>.</mml:mo>
</mml:mrow>
</mml:math>
<label>(17)</label>
</disp-formula>
</p>
<p>The corresponding analytical solution is shown in <xref ref-type="disp-formula" rid="e18">Equation 18</xref>
<disp-formula id="e18">
<mml:math id="m69">
<mml:mrow>
<mml:mi>u</mml:mi>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>&#x3d;</mml:mo>
<mml:mo>&#x2212;</mml:mo>
<mml:mfrac>
<mml:mrow>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:mfrac>
<mml:mi>tanh</mml:mi>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mfrac>
<mml:mrow>
<mml:msqrt>
<mml:mn>2</mml:mn>
</mml:msqrt>
</mml:mrow>
<mml:mrow>
<mml:mn>4</mml:mn>
</mml:mrow>
</mml:mfrac>
<mml:mrow>
<mml:mfenced open="(" close=")" separators="|">
<mml:mrow>
<mml:mi>x</mml:mi>
<mml:mo>&#x2212;</mml:mo>
<mml:mfrac>
<mml:mrow>
<mml:msqrt>
<mml:mn>18</mml:mn>
</mml:msqrt>
<mml:mi>t</mml:mi>
</mml:mrow>
<mml:mn>2</mml:mn>
</mml:mfrac>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
</mml:mrow>
</mml:mfenced>
</mml:mrow>
<mml:mo>&#x2b;</mml:mo>
<mml:mfrac>
<mml:mrow>
<mml:mn>1</mml:mn>
</mml:mrow>
<mml:mrow>
<mml:mn>2</mml:mn>
</mml:mrow>
</mml:mfrac>
<mml:mo>.</mml:mo>
</mml:mrow>
</mml:math>
<label>(18)</label>
</disp-formula>
</p>
<p>At time <inline-formula id="inf52">
<mml:math id="m70">
<mml:mrow>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>, the quasi-optimal choice of shape parameter is <inline-formula id="inf53">
<mml:math id="m71">
<mml:mrow>
<mml:mi>&#x3b5;</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>0.49</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula> with the corresponding <inline-formula id="inf54">
<mml:math id="m72">
<mml:mrow>
<mml:msub>
<mml:mi>L</mml:mi>
<mml:mn>2</mml:mn>
</mml:msub>
<mml:mo>&#x2212;</mml:mo>
<mml:mtext>error</mml:mtext>
</mml:mrow>
</mml:math>
</inline-formula> <inline-formula id="inf55">
<mml:math id="m73">
<mml:mrow>
<mml:mn>2.3819</mml:mn>
<mml:mo>&#xd7;</mml:mo>
<mml:msup>
<mml:mn>10</mml:mn>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>8</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula>. It is also more accurate than the most accurate result <inline-formula id="inf56">
<mml:math id="m74">
<mml:mrow>
<mml:mn>6.00</mml:mn>
<mml:mo>&#xd7;</mml:mo>
<mml:msup>
<mml:mn>10</mml:mn>
<mml:mrow>
<mml:mo>&#x2212;</mml:mo>
<mml:mn>5</mml:mn>
</mml:mrow>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> in [<xref ref-type="bibr" rid="B14">14</xref>]. <xref ref-type="fig" rid="F4">Figure 4</xref> is plotted to show that the numerical solution is highly consistent with the analytical solution at three different times <inline-formula id="inf57">
<mml:math id="m75">
<mml:mrow>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>0.1</mml:mn>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>0.5</mml:mn>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>.</p>
<fig id="F4" position="float">
<label>FIGURE 4</label>
<caption>
<p>Numerical solution and analytical solution at times <inline-formula id="inf58">
<mml:math id="m76">
<mml:mrow>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>0.1</mml:mn>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>0.5</mml:mn>
<mml:mo>,</mml:mo>
<mml:mi>t</mml:mi>
<mml:mo>&#x3d;</mml:mo>
<mml:mn>1</mml:mn>
</mml:mrow>
</mml:math>
</inline-formula>.</p>
</caption>
<graphic xlink:href="fphy-13-1616647-g004.tif">
<alt-text content-type="machine-generated">Line graph comparing analytical and numerical solutions for times t equals 0.1, 0.5, and 1. Analytical and numerical data are represented with different symbols and colors. The graph shows decreasing trends over the x-axis range of negative one to one, with u(x, t) values ranging from 0.3 to 1. A legend identifies the solution types and times.</alt-text>
</graphic>
</fig>
</sec>
</sec>
<sec sec-type="conclusion" id="s4">
<title>4 Conclusion</title>
<p>This study introduces a novel one-level meshless method for solving the one-dimensional nonlinear Fisher&#x2019;s equation, leveraging space-time radial basis functions (RBFs). The key findings are summarized as follows:<list list-type="simple">
<list-item>
<p>&#x2022; The use of space-time RBFs eliminates the requirement for the traditional two-level numerical procedure (e.g., separate time-stepping and spatial discretization), significantly reducing computational complexity.</p>
</list-item>
<list-item>
<p>&#x2022;The meshless nature of the method avoids reliance on structured grids, making it suitable for problems with complex geometries or dynamic boundaries.</p>
</list-item>
<list-item>
<p>&#x2022;Numerical experiments demonstrate that the method achieves high accuracy (e.g., compared to analytical solutions) while maintaining low computational costs, particularly for long-term simulations.</p>
</list-item>
</list>
</p>
<p>In conclusion, the proposed one-level meshless method provides an efficient and flexible numerical tool for solving time-dependent partial differential equations, particularly in terms of simplifying procedures.&#x200c; As a meshfree collocation method, the proposed method has similar limitations with the other collocation methods. Substantial theoretical groundwork, particularly regarding convergence and stability in generalized frameworks, remains unexplored. These aspects will be systematically investigated in future studies.</p>
</sec>
</body>
<back>
<sec sec-type="data-availability" id="s5">
<title>Data availability statement</title>
<p>The original contributions presented in the study are included in the article/<xref ref-type="sec" rid="s11">Supplementary Material</xref>, further inquiries can be directed to the corresponding authors.</p>
</sec>
<sec sec-type="author-contributions" id="s6">
<title>Author contributions</title>
<p>YJ: Validation, Data curation, Funding acquisition, Conceptualization, Supervision, Writing &#x2013; original draft. FW: Writing &#x2013; review and editing, Validation, Writing &#x2013; original draft, Software, Visualization, Conceptualization, Investigation, Methodology. ZS: Conceptualization, Writing &#x2013; original draft, Writing &#x2013; review and editing, Resources, Validation, Formal Analysis, Visualization, Data curation.</p>
</sec>
<sec sec-type="funding-information" id="s7">
<title>Funding</title>
<p>The author(s) declare that financial support was received for the research and/or publication of this article. This work is partially supported by University Natural Science Research Project of Anhui Province (Project No. 2023AH050314) and Horizontal Scientific Research Funds in Huaibei Normal University (No. 2024340603000006).</p>
</sec>
<sec sec-type="COI-statement" id="s8">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="ai-statement" id="s9">
<title>Generative AI statement</title>
<p>The author(s) declare that no Generative AI was used in the creation of this manuscript.</p>
</sec>
<sec sec-type="disclaimer" id="s10">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec sec-type="supplementary-material" id="s11">
<title>Supplementary material</title>
<p>The Supplementary Material for this article can be found online at: <ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/fphy.2025.1616647/full#supplementary-material">https://www.frontiersin.org/articles/10.3389/fphy.2025.1616647/full&#x23;supplementary-material</ext-link>
</p>
<supplementary-material xlink:href="Supplementaryfile1.pdf" id="SM1" mimetype="application/pdf" xmlns:xlink="http://www.w3.org/1999/xlink"/>
</sec>
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