Front. Pharmacol. Frontiers in Pharmacology Front. Pharmacol. 1663-9812 Frontiers Media S.A. 1764401 10.3389/fphar.2025.1764401 Correction Correction: Endogenous tetrahydrobiopterin in humans: circadian rhythm, sex, race, age, and disease status Gao et al. 10.3389/fphar.2025.1764401 Gao Lan * Project administration Writing - original draft Formal Analysis Methodology Visualization Data curation Investigation Software Conceptualization Writing - review and editing Smith Neil Conceptualization Supervision Funding acquisition Writing - review and editing Kong Ronald Resources Writing - review and editing Supervision PTC Therapeutics, Inc., Warren, NJ, United States Correspondence: Lan Gao, lgao@ptcbio.com 19 12 2025 2025 16 1764401 10 12 2025 10 12 2025 12 12 2025 Copyright © 2025 Gao, Smith and Kong. 2025 Gao, Smith and Kong https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. A Correction on Endogenous tetrahydrobiopterin in humans: circadian rhythm, sex, race, age, and disease status by Gao L, Smith N and Kong R (2025). Front. Pharmacol. 16:1701617. doi: 10.3389/fphar.2025.1701617 5,6,7,8-tetrahydrobiopterin (BH4) circadian rhythm sex race age phenylketonuria (PKU) primary tetrahydrobiopterin deficiency (PBD) section-at-acceptance Drug Metabolism and Transport

Emax was erroneously written as Emax*Age.

A correction has been made to the section Results, Endogenous BH4 concentrations in participants with PBD and PKU, Participants with PKU, Paragraph Number 3:

“The Emax and AM50 values were 12.69 ng/mL and 2.70 years, respectively. There was essentially no change in central trend of endogenous BH4 concentration in participants with PKU aged >2 years. This was confirmed with the Pearson correlation analysis for data in the group aged >2 years, which yielded a correlation coefficient (R) of 0.2265 and a p-value of 0.1656 (Supplementary Figure S1).”

The original article has been updated.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Edited and reviewed by: Xin Wang, East China Normal University, China