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<journal-id journal-id-type="publisher-id">Front. Pharmacol.</journal-id>
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<subject>Correction</subject>
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<article-title>Correction: Anticancer effects of OSW-1 on glioma cells <italic>via</italic> regulation of the PI3K/AKT signal pathway: a network pharmacology approach and experimental validation <italic>in vitro</italic> and <italic>in vivo</italic>
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<alt-title alt-title-type="left-running-head">Zhan et al.</alt-title>
<alt-title alt-title-type="right-running-head">
<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fphar.2025.1754450">10.3389/fphar.2025.1754450</ext-link>
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<surname>Zhan</surname>
<given-names>Zhixin</given-names>
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<aff id="aff1">
<institution>Department of Neurosurgery, The First Hospital of Jilin University</institution>, <city>Changchun</city>, <country country="CN">China</country>
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<author-notes>
<corresp id="c001">
<label>&#x2a;</label>Correspondence: Yong Chen, <email xlink:href="mailto:chen_yong@jlu.edu.cn">chen_yong@jlu.edu.cn</email>; Haiyan Huang, <email xlink:href="mailto:huanghy@jlu.edu.cn">huanghy@jlu.edu.cn</email>
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<pub-date publication-format="electronic" date-type="pub" iso-8601-date="2025-12-11">
<day>11</day>
<month>12</month>
<year>2025</year>
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<year>2025</year>
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<volume>16</volume>
<elocation-id>1754450</elocation-id>
<history>
<date date-type="received">
<day>26</day>
<month>11</month>
<year>2025</year>
</date>
<date date-type="accepted">
<day>05</day>
<month>12</month>
<year>2025</year>
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</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2025 Zhan, Liu, Zhang, Gao, Lai, Chen and Huang.</copyright-statement>
<copyright-year>2025</copyright-year>
<copyright-holder>Zhan, Liu, Zhang, Gao, Lai, Chen and Huang</copyright-holder>
<license>
<ali:license_ref start_date="2025-12-11">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
<license-p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</license-p>
</license>
</permissions>
<related-article id="RA1" related-article-type="corrected-article" journal-id="Front. Pharmacol." journal-id-type="nlm-ta" xlink:href="10.3389/fphar.2022.967141" ext-link-type="doi">A Correction on <article-title>Anticancer effects of OSW-1 on glioma cells <italic>via</italic> regulation of the PI3K/AKT signal pathway: a network pharmacology approach and experimental validation <italic>in vitro</italic> and <italic>in vivo</italic>
</article-title> by Zhan Z, Liu Z, Zhang C, Gao H, Lai J, Chen Y and Huang H (2022). Front. Pharmacol. 13:967141. doi: <object-id>10.3389/fphar.2022.967141</object-id>
</related-article>
<kwd-group>
<kwd>OSW-1</kwd>
<kwd>glioma</kwd>
<kwd>network pharmacology</kwd>
<kwd>cell cycle</kwd>
<kwd>apoptosis</kwd>
<kwd>Pi3k/ AKt</kwd>
</kwd-group>
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<custom-meta>
<meta-name>section-in-acceptance</meta-name>
<meta-value>Pharmacology of Anti-Cancer Drugs</meta-value>
</custom-meta>
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</front>
<body>
<p>There was a mistake in <xref ref-type="fig" rid="F8">Figure 8E</xref> as published. The Total AKT1 band was inadvertently replaced with a duplicated &#x3b2;-actin band during figure assembly. The corrected <xref ref-type="fig" rid="F8">Figure 8</xref> appears below.</p>
<fig id="F8" position="float">
<label>FIGURE 8</label>
<caption>
<p>OSW-1 inhibited tumor growth in the xenograft model mice <bold>(A)</bold> The tumors of control mice and OSW-1-treated mice were extracted and photographed <bold>(B,C)</bold> Inhibitions in the average volume and weight of glioma xenografts were observed after 21&#xa0;days of OSW-1 treatment <bold>(D)</bold> Body weight changes of mice during 21&#xa0;days of exposure <bold>(E)</bold> Western blotting of tumor tissue lysates. &#x2a;p &#x3c; 0.05, &#x2a;&#x2a;p &#x3c; 0.01, compared to the control group.</p>
</caption>
<graphic xlink:href="fphar-16-1754450-g008.tif">
<alt-text content-type="machine-generated">Panel A shows nude mice from the control and OSW-1 groups. Panel B depicts a line graph comparing tumor volume over 21 days, with OSW-1 showing reduced growth. Panel C presents a bar graph highlighting lower tumor weight in the OSW-1 group. Panel D displays a line graph of stable mouse weights for both groups. Panel E includes a Western blot and a bar graph illustrating protein expression levels, with marked differences in p-PI3K/PI3K and p-AKT1/AKT1 between groups.</alt-text>
</graphic>
</fig>
<p>The original article has been updated.</p>
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<title>Publisher&#x2019;s note</title>
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<p>
<bold>Edited and reviewed by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/1233358/overview">Muhammad Umer Farooq Awan</ext-link>, Government College University, Pakistan</p>
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