Front. Pharmacol. Frontiers in Pharmacology Front. Pharmacol. 1663-9812 Frontiers Media S.A. 1730938 10.3389/fphar.2025.1730938 Correction Correction: The active constituent of pine needle oil, bornyl acetate, suppresses NSCLC progression by inhibiting the PI3K/AKT/ABCB1 signaling axis Wu et al. 10.3389/fphar.2025.1730938 Wu Jieheng 1 2 * † Data curation Investigation Writing – review & editing Funding acquisition Writing – original draft Formal analysis Ren Jiaming 1 3 † Writing – original draft Visualization Formal analysis Methodology Data curation Wang Lu 1 † Methodology Formal analysis Investigation Writing – original draft Yang Zeyang 1 Investigation Project administration Writing – original draft Wang Xuanyin 1 Writing – original draft Resources Project administration Data curation Tu Ziyi 1 3 Formal analysis Writing – original draft Data curation Liu Xinlei 4 5 Resources Validation Funding acquisition Writing – original draft Wang Ye 6 Writing – original draft Investigation Project administration Cao Yaxuan 7 Writing – original draft Formal analysis Data curation Zhu Xu 1 8 Data curation Writing – original draft Formal analysis Li Long 1 8 Formal analysis Writing – original draft Data curation Lu Maoqin 1 Writing – original draft Validation Resources Zhang Ying 1 Writing – original draft Investigation Methodology Wu Jinyi 3 Data curation Writing – original draft Formal analysis Cao Yu 3 5 * Data curation Supervision Methodology Conceptualization Investigation Resources Writing – original draft Writing – review & editing Funding acquisition Department of Immunology, Guizhou Medical University, Guiyang, China Tumor Immunotherapy Technology Engineering Research Center of Guizhou Medical University, Guizhou Medical University, Guiyang, China School of Public Health, the key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, China Department of Anatomy, Guizhou Medical University, Guiyang, China Guizhou Prenatal Diagnsis Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, China Department of Nursing, Guiyang Healthcare Vocational University, Guiyang, China School of Clinical Medicine, Guizhou Medical University, Guiyang, China Department of Thoracic Surgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, China Correspondence: Jieheng Wu, immunewjh@163.com, wujiehen@gmc.edu.cn; Yu Cao, caoyu@gmc.edu.cn

These authors have contributed equally to this work

 13 11 2025 2025 16 1730938 23 10 2025 30 10 2025 Copyright © 2025 Wu, Ren, Wang, Yang, Wang, Tu, Liu, Wang, Cao, Zhu, Li, Lu, Zhang, Wu and Cao. 2025 Wu, Ren, Wang, Yang, Wang, Tu, Liu, Wang, Cao, Zhu, Li, Lu, Zhang, Wu and Cao https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. A Correction on The active constituent of pine needle oil, bornyl acetate, suppresses NSCLC progression by inhibiting the PI3K/AKT/ABCB1 signaling axis by Wu J, Ren J, Wang L, Yang Z, Wang X, Tu Z, Liu X, Wang Y, Cao Y, Zhu X, Li L, Lu M, Zhang Y, Wu J and Cao Y (2025). Front. Pharmacol. 16:1653461. doi: 10.3389/fphar.2025.1653461 bornyl acetate NSCLC PI3K/AKT ABCB1 tumor progression section-in-acceptance Pharmacology of Anti-Cancer Drugs

There was a mistake in Figure 5B as published. During a recent review of the figures, we discovered a duplication in Figure 5B, specifically in the panel showing the in vivo imaging results of the saline control group on Day 22. The images for the third and fourth mice were inadvertently repeated during the figure preparation process. We have carefully rechecked the original data and confirmed that the error occurred during figure assembly and layout, and not in the experimental data itself. The underlying findings and conclusions of the study remain valid and unaffected. The corrected Figure 5 appears below.

Borneol acetate inhibits NCI-H460 tumor growth in vivo. (A) Experimental schema: Nude mice received subcutaneous injections of 2 × 106 NCI-H460-luciferase cells. Vehicle, PNO, or BA were administered via tail vein. Tumor progression was monitored by bioluminescence imaging (BLI); tumors and organs were harvested terminally. (B) BLI pseudocolor images on days 8, 15, and 22. (C) Quantified fluorescence intensity. Data represent mean ± SD (*p < 0.001, p < 0.0001). (D) Excised tumors. Reduced BA group volume demonstrates tumor suppression. (E) Tumor weight quantification (p < 0.0001). (F) H&E-stained tumor sections. (G) Immunofluorescence staining of tumor sections: ABCB1 (blue, resistance marker), Ki67 (green, proliferation marker), TUNEL (red, apoptosis marker). Scale bar: 50 µm. (H) Quantified immunofluorescence intensity. Data represent mean ± SD (**p < 0.01, ***p < 0.001, ****p < 0.0001). (I) H&E staining of liver, spleen, lung, and kidney sections. (J) Liver/kidney function indices (ns p > 0.05).

Scientific study on tumor treatment in mice includes multiple panels: Panel A illustrates the experimental timeline and procedure; Panel B displays imaging results over time; Panel C is a line graph showing tumor volume changes; Panel D shows excised tumors; Panel E is a bar graph of tumor weights; Panel F presents tissue histology images; Panel G shows biomarker staining; Panel H contains bar graphs of positive cell percentages; Panel I presents organ histology images; Panel J displays bar graphs of biochemical parameters. Statistical significance is indicated with asterisks.

The original article has been updated.

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Edited and reviewed by: Vincent Kam Wai Wong, Macau University of Science and Technology, Macao SAR, China