Front. Pharmacol.Frontiers in PharmacologyFront. Pharmacol.1663-9812Frontiers Media S.A.163660710.3389/fphar.2025.1636607PharmacologyCorrectionCorrection: Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiotaRuan et al.10.3389/fphar.2025.1636607RuanLingyu1†WangZhennan2†ZhengMengyun1ZhengQi3QingQing1LinHongyan1TaoYuheng1WangLiqun1WangJunsong3*GeWenhao45*1School of Pharmacy and School of Biological and Food Engineering, Changzhou University, Changzhou, China2School of Pharmacy, Modern Industrial College of Traditional Chinese Medicine and Health, Lishui University, Lishui, China3Center of Molecular Metabolism, Nanjing University of Science and Technology, Nanjing, China4The Second People’s Hospital of Changzhou, The Third Affiliated Hospital of Nanjing Medical University, Changzhou, China5Changzhou Medical Center, Nanjing Medical University, Changzhou, China
Edited and reviewed by:Michael Heinrich, University College London, United Kingdom
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A Correction on Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota by Ruan L, Wang Z, Zheng M, Zheng Q, Qing Q, Lin H, Tao Y, Wang L, Wang J and Ge W (2025). Front. Pharmacol. 16:1580055. doi: 10.3389/fphar.2025.1580055polygoni multiflori radix praeparatapolysaccharidesacute ischemic strokegut microbiotametabolomicssection-at-acceptanceEthnopharmacology
There was an error in Figure 3 as published. The authors inadvertently substituted a 40× image from the Sham group with a 40× image from the HCK group in Figure 3A. Because intestinal histology differs markedly between groups (fold architecture, mucosal arrangement, etc.), the mismatch was readily apparent. The incorrect original 40× image of the Sham group was an enlarged image of the HCK 20× image. The authors have now retrieved the correct 40× micrographs for both the Sham and HCK groups from the raw data and have reconstructed Figure 3A accordingly. The corrected Figure 3 appears below.
PMP has an ameliorating effect on colon injury in MCAO rats. (A) Representative micrographs of H&E staining in the colon. (B) Representative immunohistochemical images and statistical maps of tight junction protein. n = 4. *p < 0.05, **p < 0.01 and ***p < 0.001, MCAO group vs. Sham group; #p < 0.05, ##p < 0.01 and ###p < 0.001, dosing group vs. MCAO group.
Histological analysis showing intestinal tissue samples across different conditions: Sham, MCAO, LM, HM, and HCK. Panel A illustrates hematoxylin and eosin staining at two magnifications (twenty times and forty times). Panel B shows immunohistochemical staining for ZO-1, Occludin, and Claudin 1. Bar graphs depict the positive rate percentages for each protein, indicating changes in expression across conditions.
There was an error in Figure 4 as published. Previously, in Figure 4B the scale bar was positioned outside the image. This has now been adjusted to ensure a consistent style. The corrected Figure 4 appears below.
PMP ameliorates MCAO-induced inflammatory response in rats' colon. Representative immunohistochemical images and statistical maps of inflammatory factors. n = 4. *p < 0.05, **p < 0.01 and ***p < 0.001, MCAO group vs. Sham group; #p < 0.05, ##p < 0.01 and ###p < 0.001, dosing group vs. MCAO group.
Histological images and bar graphs displaying TNF-α, IL-1β, IL-6, and IL-13RA2 positive rates in Sham, MCAO, LM, HM, and HCK groups. Bar graphs indicate significant differences in expression levels among these groups, with symbols denoting statistical significance.
The original version of this article has been updated.
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