Front. Pharmacol.Frontiers in PharmacologyFront. Pharmacol.1663-9812Frontiers Media S.A.161784910.3389/fphar.2025.1617849PharmacologyCorrectionCorrection: Biomineralized composite liquid crystal fiber scaffold promotes bone regeneration by enhancement of osteogenesis and angiogenesisZhan et al.10.3389/fphar.2025.1617849ZhanYi1DengBing1WuHuixian1XuChangpeng2WangRuiying1LiWenqiang3*PanZhixiong14*1Department of Orthopedic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China2Department of Orthopaedics, Guangdong Second Provincial General Hospital, Guangzhou, China3Engineering Technology Research Center for Sports Assistive Devices of Guangdong, Guangzhou Sport University, Guangzhou, China4Guangxi Health Commission Key Laboratory of Basic Research in Sphingolipid Metabolism Related Diseases, The Affiliated Hospital of Guilin Medical University, Guilin, China
Edited and reviewed by:Heike Wulff, University of California, Davis, United States
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A Correction on Biomineralized composite liquid crystal fiber scaffold promotes bone regeneration by enhancement of osteogenesis and angiogenesis by Zhan Y, Deng B, Wu H, Xu C, Wang R, Li W and Pan Z (2021). Front. Pharmacol. 12:736301. doi: 10.3389/fphar.2021.736301liquid crystal fiberbiomimetic mineralizationosteogenic differentiationvascularizationregenerationsection-at-acceptanceIntegrative and Regenerative Pharmacology
In the published article, there was an error in Figure 6A as published. It is because images from different groups were stored in the same folder during image shooting, resulting in the misuse of images. The corrected Figure 6A and its caption appear below.
(A) Alkalinephosphatase (ALP) staining and (B) its quantitative analysis of BMSC cells cultured on the scaffolds for 14 days. (C) Alizarin red (AR) staining and (D) its quantitative analysis of BMSC cells cultured on a culture plate, PLLA, PLLA/LC, and HAP-PLLA/LC fiber scaffold for 14 days, respectively. (E) Real-time quantitative PCR (RT-qPCR) analysis of osteogenic and vascularized-related gene expression of cells after culturing for 7 and 14 days.
Panel A shows ALP staining of Control, PLLA, PLLA/LC, and HAP-PLLA/LC samples, demonstrating differences in mineralization. Panel B is a bar graph depicting ALP activity over 7 and 14 days. Panel C displays ARS staining for the same conditions to highlight calcium deposits. Panel D provides a bar graph of absorbance at 540 nm over time. Panel E includes graphs of relative gene expression for Runx-2, ALP, OCN, and CD31, showing significant increases in the HAP-PLLA/LC condition. Scale bars in images indicate 50 and 500 micrometers.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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