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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Pharmacol.</journal-id>
<journal-title>Frontiers in Pharmacology</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Pharmacol.</abbrev-journal-title>
<issn pub-type="epub">1663-9812</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
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<article-meta>
<article-id pub-id-type="publisher-id">1264737</article-id>
<article-id pub-id-type="doi">10.3389/fphar.2023.1264737</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Pharmacology</subject>
<subj-group>
<subject>Correction</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Expression of Concern: A new method for ethical and efficient evidence generation for off-label medication use in oncology (a case study in glioblastoma)</article-title>
<alt-title alt-title-type="left-running-head">Frontiers Editorial Office</alt-title>
<alt-title alt-title-type="right-running-head">
<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fphar.2023.1264737">10.3389/fphar.2023.1264737</ext-link>
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<contrib contrib-type="author" corresp="yes">
<collab>Frontiers Editorial Office</collab>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/228891/overview"/>
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<author-notes>
<fn fn-type="edited-by">
<p>
<bold>Approved by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/20178/overview">Frontiers Editorial Office</ext-link>, Frontiers Media SA, Switzerland</p>
</fn>
<corresp id="c001">&#x2a;Correspondence: Frontiers Editorial Office, <email>editorial.office@frontiersin.org</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>31</day>
<month>07</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="collection">
<year>2023</year>
</pub-date>
<volume>14</volume>
<elocation-id>1264737</elocation-id>
<history>
<date date-type="received">
<day>21</day>
<month>07</month>
<year>2023</year>
</date>
<date date-type="accepted">
<day>21</day>
<month>07</month>
<year>2023</year>
</date>
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<permissions>
<copyright-statement>Copyright &#xa9; 2023 Frontiers Editorial Office.</copyright-statement>
<copyright-year>2023</copyright-year>
<copyright-holder>Frontiers Editorial Office</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
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<related-article id="RA1" related-article-type="object-of-concern" journal-id="Front. Pharmacol." journal-id-type="nlm-ta" xlink:href="10.3389/fphar.2019.00681" ext-link-type="doi">An Expression of concern on: <article-title>A new method for ethical and efficient evidence generation for off-label medication use in oncology (a case study in glioblastoma)</article-title> by Agrawal S, Vamadevan P, Mazibuko N, Bannister R, Swery R, Wilson S and Edwards S (2019). Front. Pharmacol. 10:681. doi: <object-id>10.3389/fphar.2019.00681</object-id>
</related-article>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Experimental Pharmacology and Drug Discovery</meta-value>
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</article-meta>
</front>
<body>
<p>With this notice, Frontiers states its awareness of concerns regarding the METRICS study described in this article. This expression of concern has been posted while Frontiers investigates the allegations. The situation will be updated as soon as the investigation is complete.</p>
</body>
</article>