Front. Pharmacol. Frontiers in Pharmacology Front. Pharmacol. 1663-9812 Frontiers Media S.A. 1090327 10.3389/fphar.2022.1090327 Pharmacology Correction Corrigendum: Identification of an alternative glycyrrhizin metabolite causing liquorice-induced pseudohyperaldosteronism and the development of ELISA system to detect the predictive biomarker Ishiuchi et al. 10.3389/fphar.2022.1090327 Ishiuchi Kan’ichiro 1 † Morinaga Osamu 2 † Yoshino Tetsuhiro 3 † Mitamura Miaki 1 Hirasawa Asuka 1 Maki Yasuhito 1 Tashita Yuuna 1 Kondo Tsubasa 2 Ogawa Kakuyou 2 Lian Fangyi 3 Ogawa-Ochiai Keiko 4 ‡ Minamizawa Kiyoshi 5 Namiki Takao 6 Mimura Masaru 3 Watanabe Kenji 3 Makino Toshiaki 1 * 1 Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan 2 Department of Natural Medicines, Daiichi University of Pharmacy, Fukuoka, Japan 3 Center for Kampo Medicine, Keio University School of Medicine, Tokyo, Japan 4 Department of Otorhinolaryngology and Head and Neck Surgery, Clinic of Japanese Oriental (Kampo) Medicine, Kanazawa University Hospital, Kanazawa, Japan 5 Department of Oriental Medicine, Kameda Medical Center, Kamogawa, Japan 6 Department of Japanese Oriental (Kampo) Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

Edited and reviewed by: Wei Li, Toho University, Japan

 *Correspondence: Toshiaki Makino, makino@phar.nagoya-cu.ac.jp

These authors have contributed equally to this work

‡ Present address: Kampo Clinical Center, Department of General Medicine, Hiroshima University Hospital, Hiroshima, Japan

This article was submitted to Ethnopharmacology, a section of the journal Frontiers in Pharmacology

 24 11 2022 2022 13 1090327 05 11 2022 10 11 2022 Copyright © 2022 Ishiuchi, Morinaga, Yoshino, Mitamura, Hirasawa, Maki, Tashita, Kondo, Ogawa, Lian, Ogawa-Ochiai, Minamizawa, Namiki, Mimura, Watanabe and Makino. 2022 Ishiuchi, Morinaga, Yoshino, Mitamura, Hirasawa, Maki, Tashita, Kondo, Ogawa, Lian, Ogawa-Ochiai, Minamizawa, Namiki, Mimura, Watanabe and Makino

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 A Corrigendum on Identification of an alternative glycyrrhizin metabolite causing liquorice-induced pseudohyperaldosteronism and the development of ELISA system to detect the predictive biomarker by Ishiuchi K, Morinaga O, Yoshino T, Mitamura M, Hirasawa A, Maki Y, Tashita Y, Kondo T, Ogawa K, Lian F, Ogawa-Ochiai K, Minamizawa K, Namiki T, Mimura M, Watanabe K and Makino T (2021). Front. Pharmacol. 12:688508. doi: 10.3389/fphar.2021.688508 kampo medicine side effect liquorice glycyrrhizin pseudoaldosteronism sex differences

In the published article, there was an error. The numbers of the concentrations were mistaken.

A correction has been made to Results, Pharmacokinetics of GA metabolites in female and male EHBRs orally treated with GA, Paragraph 7. These sentences previously stated:

“The concentrations of GA and its metabolites 12 h after oral administration of GA in female EHBRs were 3.2 µM of GA, 0.1 µM of 3MGA, 14 µM of 1, 4.3 µM of 2, 6.6 µM of 3, and 166 µM of 4.”

and

“The concentrations of GA and its metabolites 12 h after oral administration of GA in male EHBRs were 2.6 µM of GA, 1.2 µM of 3MGA, 102 µM of 1, 4.1 µM of 2, 1.2 µM of 3, and 198 µM of 4.”

The corrected sentences appear below:

“The concentrations of GA and its metabolites 12 h after oral administration of GA in female EHBRs were 2.7 µM of GA, 0.1 µM of 3MGA, 32 µM of 1, 10 µM of 2, 2.0 µM of 3, and 208 µM of 4.”

and

“The concentrations of GA and its metabolites 12 h after oral administration of GA in male EHBRs were 2.6 µM of GA, 1.6 µM of 3MGA, 177 µM of 1, 8.2 µM of 2, 2.2 µM of 3, and 237 µM of 4.”

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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