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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Pediatr.</journal-id>
<journal-title>Frontiers in Pediatrics</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Pediatr.</abbrev-journal-title>
<issn pub-type="epub">2296-2360</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fped.2025.1526459</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Pediatrics</subject>
<subj-group>
<subject>Review</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Global visualization of adolescent idiopathic scoliosis treatment: a bibliometric analysis</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" equal-contrib="yes"><name><surname>Zheng</surname><given-names>Xiaodong</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="author-notes" rid="an1"><sup>&#x2020;</sup></xref><uri xlink:href="https://loop.frontiersin.org/people/2729804/overview"/><role content-type="https://credit.niso.org/contributor-roles/conceptualization/"/><role content-type="https://credit.niso.org/contributor-roles/formal-analysis/"/><role content-type="https://credit.niso.org/contributor-roles/methodology/"/><role content-type="https://credit.niso.org/contributor-roles/validation/"/><role content-type="https://credit.niso.org/contributor-roles/visualization/"/><role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author" equal-contrib="yes"><name><surname>Han</surname><given-names>Wenjin</given-names></name>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
<xref ref-type="author-notes" rid="an1"><sup>&#x2020;</sup></xref><uri xlink:href="https://loop.frontiersin.org/people/2637155/overview" /><role content-type="https://credit.niso.org/contributor-roles/visualization/"/><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author"><name><surname>Gao</surname><given-names>Shan</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref><role content-type="https://credit.niso.org/contributor-roles/visualization/"/><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author"><name><surname>Jia</surname><given-names>MengLong</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref><role content-type="https://credit.niso.org/contributor-roles/formal-analysis/"/><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author"><name><surname>Liu</surname><given-names>LiJun</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref><role content-type="https://credit.niso.org/contributor-roles/conceptualization/"/><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Yu</surname><given-names>Longtan</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref><uri xlink:href="https://loop.frontiersin.org/people/2933969/overview" /><role content-type="https://credit.niso.org/contributor-roles/methodology/"/><role content-type="https://credit.niso.org/contributor-roles/visualization/"/><role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
</contrib-group>
<aff id="aff1"><label><sup>1</sup></label><institution>The First Clinical School, Shandong University of Traditional Chinese Medicine</institution>, <addr-line>Jinan</addr-line>, <country>China</country></aff>
<aff id="aff2"><label><sup>2</sup></label><institution>Department of Orthopedic Spine, Weifang Hospital of Traditional Chinese Medicine</institution>, <addr-line>Weifang</addr-line>, <country>China</country></aff>
<aff id="aff3"><label><sup>3</sup></label><institution>School of Nursing, Xi&#x2019;an Jiaotong University Health Science Center</institution>, <addr-line>Xi&#x2019;an</addr-line>, <country>China</country></aff>
<author-notes>
<fn fn-type="edited-by"><p><bold>Edited by:</bold> Antonella Muscella, University of Salento, Italy</p></fn>
<fn fn-type="edited-by"><p><bold>Reviewed by:</bold> Boris Banjevic, University of Montenegro, Montenegro</p>
<p>Mshari Alghadier, Prince Sattam bin Abdulaziz University, Saudi Arabia</p></fn>
<corresp id="cor1"><label>&#x002A;</label><bold>Correspondence:</bold> Longtan Yu <email>18553354680@163.com</email></corresp>
<fn fn-type="equal" id="an1"><label><sup>&#x2020;</sup></label><p>These authors share first authorship</p></fn>
</author-notes>
<pub-date pub-type="epub"><day>04</day><month>02</month><year>2025</year></pub-date>
<pub-date pub-type="collection"><year>2025</year></pub-date>
<volume>13</volume><elocation-id>1526459</elocation-id>
<history>
<date date-type="received"><day>11</day><month>11</month><year>2024</year></date>
<date date-type="accepted"><day>13</day><month>01</month><year>2025</year></date>
</history>
<permissions>
<copyright-statement>&#x00A9; 2025 Zheng, Han, Gao, Jia, Liu and Yu.</copyright-statement>
<copyright-year>2025</copyright-year><copyright-holder>Zheng, Han, Gao, Jia, Liu and Yu</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<abstract><sec><title>Objective</title>
<p>The objective of this study is to present a comprehensive overview of current advancements, prominent areas of interest, emerging trends, and frontiers in global research concerning the treatment of adolescent idiopathic scoliosis. The aim is to offer valuable insights and guidance for future research endeavors in this field.</p>
</sec><sec><title>Methods</title>
<p>We conducted a literature search on the treatment of adolescent idiopathic scoliosis using the Web of Science Core Collection database spanning from 2009 to 2024. Visualization of countries, institutions, authors, and keywords was performed using CiteSpace.</p>
</sec><sec><title>Results</title>
<p>1,002 English articles were included in this study. Between 2009 and 2020, publications remained relatively low and stable. However, in 2021, interest in the treatment of adolescent idiopathic scoliosis began to surge, a noticeable increase in publications, with a peak reached in 2022. The United States emerged as the leading contributor among countries, institutions, and authors. Nanjing University and Peter O. Newton were the most prolific institutions and authors, respectively. The academic journal with the highest number of published articles was Spine. Notably, areas such as Cobb angle measurement, the efficacy of non-surgical treatments for AIS, and factors influencing the success of brace treatment garnered significant attention as hot topics in adolescent idiopathic scoliosis treatment.</p>
</sec><sec><title>Conclusion</title>
<p>The prognosis remains consistent across patients with varying degrees of curvature in adolescent idiopathic scoliosis. Given the limited understanding of its etiology, the relationship between curvature and prognosis, as well as the exploration of its underlying causes, could emerge as new research directions in the future.</p>
</sec>
</abstract>
<kwd-group>
<kwd>bibliometrics</kwd>
<kwd>adolescent idiopathic scoliosis</kwd>
<kwd>treatment</kwd>
<kwd>CiteSpace</kwd>
<kwd>visual analysis bibliometrics</kwd>
<kwd>visual analysis</kwd>
</kwd-group><contract-num rid="cn001">Q-2023034</contract-num><contract-num rid="cn002">Z-2022023</contract-num><contract-num rid="cn003">2022YX015</contract-num><contract-sponsor id="cn001">Shandong Provincial Traditional Chinese Medicine Science and Technology Project</contract-sponsor><contract-sponsor id="cn002">Shandong Provincial Traditional Chinese Medicine Science and Technology Project</contract-sponsor><contract-sponsor id="cn003">Weifang Science and Technology Development Plan</contract-sponsor><counts>
<fig-count count="7"/>
<table-count count="4"/><equation-count count="0"/><ref-count count="35"/><page-count count="13"/><word-count count="0"/></counts><custom-meta-wrap><custom-meta><meta-name>section-at-acceptance</meta-name><meta-value>Pediatric Orthopedics</meta-value></custom-meta></custom-meta-wrap>
</article-meta>
</front>
<body><sec id="s1" sec-type="intro"><label>1</label><title>Introduction</title>
<p>Adolescent idiopathic scoliosis is the primary cause of three-dimensional spine deformities. It is officially defined by the Scoliosis Research Society as a spinal deformity characterized by a coronal Cobb angle exceeding 10&#x00B0; (<xref ref-type="bibr" rid="B1">1</xref>). Adolescent idiopathic scoliosis is an abnormal curvature of the spine that occurs in late childhood or adolescence (<xref ref-type="bibr" rid="B2">2</xref>, <xref ref-type="bibr" rid="B3">3</xref>). Adolescence is a pivotal period marked by self-perception and self-esteem development, a time when developmental changes such as scoliosis can profoundly impact both the physical and mental health of young individuals. This stage of life is particularly sensitive to psychological development, with research indicating that adolescents with scoliosis are more susceptible than adults to experiencing psychological distress. Such distress can significantly diminish their quality of life (<xref ref-type="bibr" rid="B4">4</xref>). Therefore, it is necessary to conduct in-depth research on the treatment of adolescent idiopathic scoliosis.</p>
<p>Adolescent Idiopathic Scoliosis (AIS) is a common spinal deformity in adolescents, with treatment options varying based on individual differences. Current methods primarily include observation, bracing, physical therapy, and surgical intervention. Observation is suitable for patients with mild curvature, and when combined with sensors, it allows for real-time monitoring. Bracing treatments utilize innovative technologies like 3D printing and dynamic braces to enhance comfort and effectiveness (<xref ref-type="bibr" rid="B5">5</xref>). Physical therapy can incorporate virtual reality to assist with posture correction. Surgical treatments focus on minimally invasive techniques and navigational applications, improving both safety and correction outcomes (<xref ref-type="bibr" rid="B6">6</xref>). Additionally, the application of biomaterials and robotic technologies offers emerging treatment options. By integrating genetic analysis and intelligent algorithms, precise predictions of disease progression and personalized treatment plans can be achieved. The application of new technologies is advancing the scientific and individualized approach to AIS treatment.</p>
<p>While numerous scholars have explored adolescent idiopathic scoliosis, the field lacks comprehensive visualization analysis, hindering the identification of current research trends and future directions. Visual research methodologies can illuminate rigorous data, uncover research hotspots and frontiers, and offer detailed insights into the dynamic development and overall structure of the field. This paper seeks to bridge this gap by employing bibliometric and visual analysis to summarize the current landscape, highlight hotspots, identify emerging trends, and delineate frontiers in global research on adolescent idiopathic scoliosis. The findings aim to provide theoretical foundations for future investigations in related areas.</p>
</sec>
<sec id="s2" sec-type="methods"><label>2</label><title>Methods</title>
<sec id="s2a"><label>2.1</label><title>Literature search queries</title>
<p>While databases like PubMed, Elsevier, and others serve the purpose of literature research, Web of Science stands out as the premier choice for bibliometric analysis. Therefore, the literature included in this study is sourced exclusively from the Web of Science Core Collection (WOSCC). The search query employed is as follows: (Adolescent&#x002A; OR Adolescence OR Teen&#x002A; OR Teenager&#x002A; OR Youth&#x002A;) AND (&#x201C;idiopathic scoliosis&#x201D;) AND (Therapeutic OR Therapy OR Therapie&#x002A; OR Treatment&#x002A;).</p>
</sec>
<sec id="s2b"><label>2.2</label><title>Literature screening</title>
<p>A systematic literature search was conducted on the treatment of adolescent idiopathic scoliosis from 2009 to 2024, focusing on articles in the English language. A total of 3,961 articles were initially identified. Inclusion criteria were set to include articles with essential information such as abstracts, keywords, and author affiliations, while exclusion criteria targeted literature unrelated to adolescent scoliosis treatment and non-article formats like conference abstracts, news reports, and letters. Following these criteria, 2,760 articles were screened, resulting in 1,201 articles deemed highly relevant. These 1,201 articles underwent detailed analysis to extract information regarding countries, institutions, authors, and keywords. It&#x0027;s important to note that this entire research process was conducted by a single researcher.</p>
</sec>
<sec id="s2c"><label>2.3</label><title>Analytical tools</title>
<p>In this literature analysis, we focused on examining countries, institutions, authors, keywords, and article citations. The visual representation comprises nodes and links, where nodes represent various entities such as countries, institutions, authors, keywords, and citations. The size of a node corresponds to the number of published papers associated with it, while the number and thickness of links between nodes indicate their proximity. Node and link colors signify different years. Additionally, the centrality of a node, indicating its importance and centrality in the knowledge network, is represented by the thickness of the purple ring surrounding it. A thicker purple ring denotes higher centrality. We configured CiteSpace with the following parameters: (1) a time span from January 2009 to April 2024, with each slice year equal to 1; (2) source of terms includes title, abstract, author&#x0027;s keyword, and keyword plus; (3) node types consist of country, institution, author, keyword, and reference; (4) threshold selection criteria were set to the first 50 items of each time slice, with other settings remaining at default values. For modular <italic>Q</italic>, a value greater than 0.3 indicates a significant cluster structure. Silhouette (S) values above 0.5 suggest reasonable clustering results, while values exceeding 0.7 indicate extremely reliable clustering outcomes.</p>
</sec>
</sec>
<sec id="s3" sec-type="results"><label>3</label><title>Results</title>
<sec id="s3a"><label>3.1</label><title>Literature search and screening results</title>
<p>In this study, a comprehensive search yielded a total of 3,961 English-language literature items. Through meticulous screening, 2,760 articles deemed irrelevant to the study&#x0027;s focus were excluded. Ultimately, 1,201 articles, meeting stringent inclusion and screening criteria, were identified as highly relevant and retained for further analysis.</p>
</sec>
<sec id="s3b"><label>3.2</label><title>Publication years and journals</title>
<p>A total of 1,201 articles on the treatment of adolescent idiopathic scoliosis were retrieved from the Web of Science Core Collection (WOSCC) database, and all 1,201 were original research articles, accounting for 100&#x0025; of the retrieved literature. <xref ref-type="fig" rid="F1">Figure&#x00A0;1</xref> depicts the annual distribution of these publications from 2009 to 2024. The blue line represents the proportion of articles published in a given year relative to the total, while the orange bar chart indicates the absolute number of papers published in each year. As illustrated in <xref ref-type="fig" rid="F1">Figure&#x00A0;1</xref>, the number of publications remained relatively low and stable between 2009 and 2020. However, starting in 2021, there was a noticeable increase in the popularity of research on adolescent idiopathic scoliosis treatment, with the number of publications trending upward. This trend peaked in 2022, and its popularity has remained high over the past three years. This suggests a growing interest and emphasis on research in this area, potentially driven by advancements in treatment methods or an increased awareness of the condition.</p>
<fig id="F1" position="float"><label>Figure 1</label>
<caption><p>This figure illustrates the annual distribution of publications related to the treatment of adolescent idiopathic scoliosis from 2009 to 2024. The blue line represents the proportion of papers published each year relative to the total, while the orange bars indicate the absolute number of papers published annually. The data shows a steady increase in publications starting in 2021, peaking in 2022, and maintaining high levels in subsequent years, reflecting a growing interest and focus on this topic within the academic community.</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fped-13-1526459-g001.tif"/>
</fig>
<p>The table (<xref ref-type="table" rid="T1">Table&#x00A0;1</xref>) highlights the distribution of articles across 269 journals from 2009 to 2024, focusing on adolescent idiopathic scoliosis treatment. Notably, Spine emerged as the leading publisher with 176 papers (14.65&#x0025;), followed by the European Spine Journal with 129 papers (10.74&#x0025;).</p>
<table-wrap id="T1" position="float"><label>Table 1</label>
<caption><p>Top 10 journals with the most publications on the treatment of adolescent idiopathic scoliosis.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="center"/>
<col align="left"/>
<col align="center"/>
<col align="center"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Rank</th>
<th valign="top" align="center">Journal</th>
<th valign="top" align="center">Number (&#x0025;)</th>
<th valign="top" align="center">Country</th>
<th valign="top" align="center">IF<xref ref-type="table-fn" rid="table-fn1"><sup>a</sup></xref></th>
<th valign="top" align="left">JCR quartile</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">1</td>
<td valign="top" align="left">Spine</td>
<td valign="top" align="center">176 (14.65)</td>
<td valign="top" align="left">USA</td>
<td valign="top" align="center">3</td>
<td valign="top">Q2</td>
</tr>
<tr>
<td valign="top">2</td>
<td valign="top">European Spine Journal</td>
<td valign="top" align="center">129 (10.74)</td>
<td valign="top">USA</td>
<td valign="top" align="center">2.8</td>
<td valign="top">Q2</td>
</tr>
<tr>
<td valign="top">3</td>
<td valign="top">Spine Deformity</td>
<td valign="top" align="center">67 (5.58)</td>
<td valign="top">GERMANY (FED REP GER)</td>
<td valign="top" align="center">1.6</td>
<td valign="top">Q3</td>
</tr>
<tr>
<td valign="top">4</td>
<td valign="top">Journal of Pediatric Orthopedics</td>
<td valign="top" align="center">50 (4.16)</td>
<td valign="top">USA</td>
<td valign="top" align="center">1.7</td>
<td valign="top">Q2</td>
</tr>
<tr>
<td valign="top">5</td>
<td valign="top">Spine Journal</td>
<td valign="top" align="center">31 (2.58)</td>
<td valign="top">USA</td>
<td valign="top" align="center">4.5</td>
<td valign="top">Q1</td>
</tr>
<tr>
<td valign="top">6</td>
<td valign="top">Journal of Clinical Medicine</td>
<td valign="top" align="center">30 (2.50)</td>
<td valign="top">SWITZERLAND</td>
<td valign="top" align="center">3.9</td>
<td valign="top">Q1</td>
</tr>
<tr>
<td valign="top">7</td>
<td valign="top">Children-Basel</td>
<td valign="top" align="center">24 (2.00)</td>
<td valign="top">SWITZERLAND</td>
<td valign="top" align="center">2.4</td>
<td valign="top">Q2</td>
</tr>
<tr>
<td valign="top">8</td>
<td valign="top">Bmc Musculoskeletal Disorders</td>
<td valign="top" align="center">24 (2.00)</td>
<td valign="top">ENGLAND</td>
<td valign="top" align="center">2.3</td>
<td valign="top">Q4</td>
</tr>
<tr>
<td valign="top">9</td>
<td valign="top">Journal of Bone and Joint Surgery-American Volume</td>
<td valign="top" align="center">23 (1.92)</td>
<td valign="top">USA</td>
<td valign="top" align="center">5.3</td>
<td valign="top">Q1</td>
</tr>
<tr>
<td valign="top">10</td>
<td valign="top">Clinical Spine Surgery</td>
<td valign="top" align="center">21 (1.75)</td>
<td valign="top">USA</td>
<td valign="top" align="center">1.9</td>
<td valign="top">Q3</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="table-fn1"><label><sup>a</sup></label>
<p>The IF were obtained from the 2022 Journal Citation Reports (JCR).</p></fn>
</table-wrap-foot>
</table-wrap>
<p>The top 10 journals collectively accounted for 47.88&#x0025; of all publications, with impact factors ranging between 1.7 and 5.3. Approximately 30&#x0025; of these journals were positioned in the Q1 region, denoting high-quality publications. Remarkably, the Journal of Bone and Joint Surgery American Volume boasted the highest impact factor at 5.3, with other journals averaging an impact factor of 2.70.</p>
</sec>
<sec id="s3c"><label>3.3</label><title>Collaboration analysis</title>
<sec id="s3c1"><label>3.3.1</label><title>Country-by-country cooperation analysis</title>
<p>The study of adolescent idiopathic scoliosis treatment demonstrates significant international collaboration, as depicted in <xref ref-type="fig" rid="F2">Figure&#x00A0;2</xref>, a country/region network diagram comprising 61 nodes and 242 lines, with a network density of 0.1322. Leading the research efforts, the United States contributed the most, with 296 articles (22.46&#x0025;), followed by China and Canada, with 209 (15.86&#x0025;) and 89 articles (6.75&#x0025;), respectively. Collectively, these top three countries accounted for 594 papers, representing 45.07&#x0025; of the total. Regarding collaboration, the United States emerges as a central player with a centrality share of 0.36, followed by China at 0.18. Notably, the United States maintains robust collaboration with other countries, facilitating knowledge exchange and collective advancement in adolescent idiopathic scoliosis treatment research. (Refer to <xref ref-type="table" rid="T2">Table&#x00A0;2</xref> for further details).</p>
<fig id="F2" position="float"><label>Figure 2</label>
<caption><p>2013&#x2013;2023 country cooperation network diagram.</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fped-13-1526459-g002.tif"/>
</fig>
<table-wrap id="T2" position="float"><label>Table 2</label>
<caption><p>Top 10 countries, institutions, and authors in the study.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="center"/>
<col align="center"/>
<col align="left"/>
<col align="center"/>
<col align="center"/>
<col align="left"/>
<col align="center"/>
<col align="center"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">No.</th>
<th valign="top" align="center">Countries/Regions</th>
<th valign="top" align="center">Count (&#x0025;)</th>
<th valign="top" align="center">Centrality</th>
<th valign="top" align="center">Institution</th>
<th valign="top" align="center">Count (&#x0025;)</th>
<th valign="top" align="center">Centrality</th>
<th valign="top" align="center">Authors</th>
<th valign="top" align="center">Count (&#x0025;)</th>
<th valign="top" align="center">Centrality</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">1</td>
<td valign="top" align="left">USA</td>
<td valign="top" align="center">296 (22.46)</td>
<td valign="top" align="center">0.36</td>
<td valign="top" align="left">Nanjing University</td>
<td valign="top" align="center">22 (1.88)</td>
<td valign="top" align="center">0.00</td>
<td valign="top" align="left">Newton, Peter O</td>
<td valign="top" align="center">31 (2.27)</td>
<td valign="top" align="center">0.12</td>
</tr>
<tr>
<td valign="top" align="left">2</td>
<td valign="top" align="left">PEOPLES R CHINA</td>
<td valign="top" align="center">209 (15.86)</td>
<td valign="top" align="center">0.18</td>
<td valign="top" align="left">Shriners Hospitals Children Philadelphia</td>
<td valign="top" align="center">16 (1.37)</td>
<td valign="top" align="center">0.00</td>
<td valign="top" align="left">Qiu, Yong</td>
<td valign="top" align="center">26 (1.90)</td>
<td valign="top" align="center">0.04</td>
</tr>
<tr>
<td valign="top" align="left">3</td>
<td valign="top" align="left">CANADA</td>
<td valign="top" align="center">89 (6.75)</td>
<td valign="top" align="center">0.17</td>
<td valign="top" align="left">Univ Hong Kong</td>
<td valign="top" align="center">16 (1.37)</td>
<td valign="top" align="center">0.00</td>
<td valign="top" align="left">Shah, Suken A</td>
<td valign="top" align="center">25 (1.83)</td>
<td valign="top" align="center">0.03</td>
</tr>
<tr>
<td valign="top" align="left">4</td>
<td valign="top" align="left">JAPAN</td>
<td valign="top" align="center">85 (6.45)</td>
<td valign="top" align="center">0.03</td>
<td valign="top" align="left">Rady Childrens Hosp</td>
<td valign="top" align="center">15 (1.28)</td>
<td valign="top" align="center">0.00</td>
<td valign="top" align="left">Parent, Stefan</td>
<td valign="top" align="center">21 (1.54)</td>
<td valign="top" align="center">0.03</td>
</tr>
<tr>
<td valign="top" align="left">5</td>
<td valign="top" align="left">ITALY</td>
<td valign="top" align="center">68 (5.16)</td>
<td valign="top" align="center">0.11</td>
<td valign="top" align="left">Universite de Montreal</td>
<td valign="top" align="center">14 (1.20)</td>
<td valign="top" align="center">0.00</td>
<td valign="top" align="left">Zhu, Zezhang</td>
<td valign="top" align="center">18 (1.32)</td>
<td valign="top" align="center">0.00</td>
</tr>
<tr>
<td valign="top" align="left">6</td>
<td valign="top" align="left">TURKEY</td>
<td valign="top" align="center">58 (4.40)</td>
<td valign="top" align="center">0.06</td>
<td valign="top" align="left">University of Hong Kong</td>
<td valign="top" align="center">13 (1.11)</td>
<td valign="top" align="center">0.00</td>
<td valign="top" align="left">Samdani, Amer F</td>
<td valign="top" align="center">17 (1.24)</td>
<td valign="top" align="center">0.01</td>
</tr>
<tr>
<td valign="top" align="left">7</td>
<td valign="top" align="left">FRANCE</td>
<td valign="top" align="center">47 (3.57)</td>
<td valign="top" align="center">0.01</td>
<td valign="top" align="left">UDICE-French Research Universities</td>
<td valign="top" align="center">13 (1.11)</td>
<td valign="top" align="center">0.00</td>
<td valign="top" align="left">Yaszay, Burt</td>
<td valign="top" align="center">16 (1.17)</td>
<td valign="top" align="center">0.01</td>
</tr>
<tr>
<td valign="top" align="left">8</td>
<td valign="top" align="left">GERMANY</td>
<td valign="top" align="center">47 (3.57)</td>
<td valign="top" align="center">0.16</td>
<td valign="top" align="left">Childrens Hosp Philadelphia</td>
<td valign="top" align="center">13 (1.11)</td>
<td valign="top" align="center">0.00</td>
<td valign="top" align="left">Bastrom, Tracey P</td>
<td valign="top" align="center">15 (1.10)</td>
<td valign="top" align="center">0.01</td>
</tr>
<tr>
<td valign="top" align="left">9</td>
<td valign="top" align="left">SOUTH KOREA</td>
<td valign="top" align="center">41 (3.11)</td>
<td valign="top" align="center">0.00</td>
<td valign="top" align="left">Rady Childrens Hospital San Diego</td>
<td valign="top" align="center">13 (1.11)</td>
<td valign="top" align="center">0.00</td>
<td valign="top" align="left">Sudo, Hideki</td>
<td valign="top" align="center">13 (0.95)</td>
<td valign="top" align="center">0.04</td>
</tr>
<tr>
<td valign="top" align="left">10</td>
<td valign="top" align="left">POLAND</td>
<td valign="top" align="center">30 (2.28)</td>
<td valign="top" align="center">0.07</td>
<td valign="top" align="left">Chinese University of Hong Kong</td>
<td valign="top" align="center">13 (1.11)</td>
<td valign="top" align="center">0.00</td>
<td valign="top" align="left">Cheung, Jason Pui Yin</td>
<td valign="top" align="center">12 (0.88)</td>
<td valign="top" align="center">0.05</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="s3c2"><label>3.3.2</label><title>Analysis of inter-agency collaboration</title>
<p>This paper presents a network diagram, depicted in <xref ref-type="fig" rid="F3">Figure&#x00A0;3</xref>, which illustrates the collaborative relationships between institutions involved in research on adolescent idiopathic scoliosis treatment. The network comprises 359 nodes representing different institutions and 847 links indicating collaborative ties between them, with a network density of 0.0132. Notably, Nanjing University emerges as a significant contributor, with 22 papers (1.88&#x0025;), followed by Shriners Hospitals for Children in Philadelphia with 16 papers (1.37&#x0025;). Universities dominate the list of top contributors, representing 60&#x0025; of the top 10 institutions based on the number of papers published. However, despite the prolific output of these institutions, the analysis reveals relatively weak cooperation among them, as indicated by the correlation of statistical agencies. This suggests opportunities for enhancing collaboration to foster greater synergy and impact in the field of adolescent idiopathic scoliosis treatment research. (Refer to <xref ref-type="table" rid="T2">Table&#x00A0;2</xref> for further details).</p>
<fig id="F3" position="float"><label>Figure 3</label>
<caption><p>Diagram of the collaboration network between the institutions of the study from 2009 to 2024.</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fped-13-1526459-g003.tif"/>
</fig>
</sec>
<sec id="s3c3"><label>3.3.3</label><title>A study of the correlation between authors</title>
<p>The research delves into the core authors contributing to the literature on adolescent idiopathic scoliosis treatment, analyzing their collaborative relationships through a network diagram (<xref ref-type="fig" rid="F4">Figure&#x00A0;4</xref>). This diagram comprises 422 nodes representing authors and 839 links indicating collaboration between them, with a network density of 0.0094. Despite the low network density, signaling limited collaboration among authors, discernible node and team relationships emerge within the network diagram. Leading the pack, Newton and Peter O stand out with 31 papers (2.27&#x0025;), followed closely by Qiu and Yong with 26 papers (1.90&#x0025;), and Shah and Suken A with 25 papers (1.83&#x0025;). The data presented in <xref ref-type="table" rid="T2">Table&#x00A0;2</xref> underscore the relatively low relevance among authors, suggesting a lack of robust collaboration within the authorship community. This observation underscores potential avenues for enhancing cooperation and knowledge exchange among authors in the field of adolescent idiopathic scoliosis treatment research.</p>
<fig id="F4" position="float"><label>Figure 4</label>
<caption><p>Network diagram of collaboration between authors and authors of the study, 2009&#x2013;2024.</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fped-13-1526459-g004.tif"/>
</fig>
</sec>
</sec>
<sec id="s3d"><label>3.4</label><title>Keyword clustering</title>
<p>Keyword clustering offers insights into hotspots and trends in the treatment of adolescent idiopathic scoliosis. The analysis encompasses 351 nodes and 2,348 links, with a network density of 0.0382. Key terms prevalent in adolescent idiopathic scoliosis treatment include &#x201C;adolescent idiopathic scoliosis,&#x201D; &#x201C;surgery,&#x201D; and &#x201C;instrumentation,&#x201D; among others (refer to <xref ref-type="table" rid="T3">Table&#x00A0;3</xref>). Noteworthy centrality measures include &#x201C;children,&#x201D; &#x201C;follow up,&#x201D; &#x201C;surgical treatment,&#x201D; &#x201C;fusion,&#x201D; and &#x201C;outcome&#x201D; (refer to <xref ref-type="table" rid="T3">Table&#x00A0;3</xref>). Through clustering, the keywords coalesce into eight distinct groups, elucidating various facets of treatment approaches. These clusters encompass &#x201C;quality of life,&#x201D; &#x201C;pedicle screw,&#x201D; &#x201C;brace treatment,&#x201D; &#x201C;pediatric,&#x201D; &#x201C;posterior spinal fusion,&#x201D; &#x201C;vertebral body tethering,&#x201D; &#x201C;selective thoracic fusion,&#x201D; and &#x201C;pedicle screw instrumentation&#x201D; (refer to <xref ref-type="fig" rid="F5">Figure&#x00A0;5</xref>). The rationality of this clustering is substantiated by <italic>Q</italic>&#x2009;&#x003D;&#x2009;0.3578 (&#x003E;0.3) and <italic>S</italic>&#x2009;&#x003D;&#x2009;0.7082 (&#x003E;0.5), affirming the coherence and relevance of the identified clusters in delineating trends and focal areas in adolescent idiopathic scoliosis treatment research.</p>
<fig id="F5" position="float"><label>Figure 5</label>
<caption><p>Keyword clustering analysis network diagram of the study from 2009 to 2024.</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fped-13-1526459-g005.tif"/>
</fig>
<table-wrap id="T3" position="float"><label>Table 3</label>
<caption><p>Keyword centrality table.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="center"/>
<col align="left"/>
<col align="center"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">No.</th>
<th valign="top" align="center">Keywords</th>
<th valign="top" align="center">Counts</th>
<th valign="top" align="center">Keywords</th>
<th valign="top" align="center">Centrality</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">1</td>
<td valign="top" align="left">adolescent idiopathic scoliosis</td>
<td valign="top" align="center">354</td>
<td valign="top" align="left">children</td>
<td valign="top" align="center">0.12</td>
</tr>
<tr>
<td valign="top" align="left">2</td>
<td valign="top" align="left">surgery</td>
<td valign="top" align="center">90</td>
<td valign="top" align="left">follow up</td>
<td valign="top" align="center">0.12</td>
</tr>
<tr>
<td valign="top" align="left">3</td>
<td valign="top" align="left">instrumentation</td>
<td valign="top" align="center">88</td>
<td valign="top" align="left">surgical treatment</td>
<td valign="top" align="center">0.11</td>
</tr>
<tr>
<td valign="top" align="left">4</td>
<td valign="top" align="left">quality of life</td>
<td valign="top" align="center">79</td>
<td valign="top" align="left">fusion</td>
<td valign="top" align="center">0.10</td>
</tr>
<tr>
<td valign="top" align="left">5</td>
<td valign="top" align="left">surgical treatment</td>
<td valign="top" align="center">76</td>
<td valign="top" align="left">outcome</td>
<td valign="top" align="center">0.10</td>
</tr>
<tr>
<td valign="top" align="left">6</td>
<td valign="top" align="left">fusion</td>
<td valign="top" align="center">73</td>
<td valign="top" align="left">spinal deformity</td>
<td valign="top" align="center">0.09</td>
</tr>
<tr>
<td valign="top" align="left">7</td>
<td valign="top" align="left">idiopathic scoliosis</td>
<td valign="top" align="center">62</td>
<td valign="top" align="left">posterior spinal fusion</td>
<td valign="top" align="center">0.08</td>
</tr>
<tr>
<td valign="top" align="left">8</td>
<td valign="top" align="left">posterior spinal fusion</td>
<td valign="top" align="center">56</td>
<td valign="top" align="left">deformity</td>
<td valign="top" align="center">0.08</td>
</tr>
<tr>
<td valign="top" align="left">9</td>
<td valign="top" align="left">pedicle screw</td>
<td valign="top" align="center">51</td>
<td valign="top" align="left">reliability</td>
<td valign="top" align="center">0.08</td>
</tr>
<tr>
<td valign="top" align="left">10</td>
<td valign="top" align="left">outcome</td>
<td valign="top" align="center">51</td>
<td valign="top" align="left">brace</td>
<td valign="top" align="center">0.08</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="s3e"><label>3.5</label><title>Keyword prominence analysis</title>
<p>The utilization of keyword highlighting serves the purpose of scrutinizing the frontier direction of adolescent scoliosis treatment. Notably, the visualization of keywords in CiteSpace reveals a significant surge in their numbers within a condensed timeframe, underscoring the intensity and temporal dynamics of keyword outbreaks (refer to <xref ref-type="fig" rid="F6">Figure&#x00A0;6</xref>). The investigation identifies 25 keywords that persisted for over a year in the study of adolescent scoliosis treatment, exhibiting a mean intensity exceeding 2. Leading the pack, &#x201C;Cobb Angle&#x201D; emerges with the highest burst intensity of 7.02. Notably, the keyword &#x201C;thoracic spine&#x201D; maintained prominence over the period 2013&#x2013;2017. Furthermore, keywords such as &#x201C;skeletally immature patients,&#x201D; &#x201C;Schroth exercises,&#x201D; &#x201C;vertebral body tethering,&#x201D; &#x201C;growth modulation,&#x201D; &#x201C;exercises,&#x201D; &#x201C;health-related quality of life,&#x201D; and &#x201C;success&#x201D; have sustained outbreaks, extending into the present and signaling potential as future research hotspots. These findings offer valuable insights into emerging trends and focal areas within the realm of adolescent scoliosis treatment research.</p>
<fig id="F6" position="float"><label>Figure 6</label>
<caption><p>Keyword prominence network diagram from 2013 to 2023.</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fped-13-1526459-g006.tif"/>
</fig>
</sec>
<sec id="s3f"><label>3.6</label><title>Co-citation timeline analysis</title>
<p>By scrutinizing the co-citation timeline, we glean insights into the evolution and trends shaping adolescent scoliosis treatment (refer to <xref ref-type="fig" rid="F7">Figure&#x00A0;7</xref>). The network diagram encompasses 502 nodes and 1,746 network links, yielding a network density of 0.0139. Notably, the diagram is delineated into 10 distinct sets, with &#x201C;3D Correction&#x201D; emerging as the largest set, followed by &#x201C;Treatment Outcome&#x201D; and &#x201C;Sagittal Alignment.&#x201D;</p>
<fig id="F7" position="float"><label>Figure 7</label>
<caption><p>Co-citation timeline network from 2009 to 2024.</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="fped-13-1526459-g007.tif"/>
</fig>
<p>The analysis reveals a high modularity index (<italic>Q</italic>&#x2009;&#x003D;&#x2009;0.7633) and a substantial silhouette score (<italic>S</italic>&#x2009;&#x003D;&#x2009;0.9122), affirming the rationality of the clustering approach. Moreover, there&#x0027;s a discernible increase in the number of nodes post-2012, with a concentration primarily observed between 2012 and 2016. Among the sets, notable citation burst nodes include &#x201C;3D orthopedics&#x201D; in group 0, &#x201C;treatment outcomes&#x201D; in group 1, and &#x201C;surgical orthopedics&#x201D; in group 3, underscoring pivotal areas of focus and innovation within adolescent scoliosis treatment research. These findings elucidate the trajectory of advancements and highlight promising avenues for further exploration in the field.</p>
<p>This article highlights 10 seminal works in the domain of adolescent scoliosis treatment (<xref ref-type="table" rid="T4">Table 4</xref>). Notably, these publications span the years 2010&#x2013;2020, with approximately 80&#x0025; being featured in Q1 journals. Impressively, 80&#x0025; of the selected literature boasts an Impact Factor (IF) exceeding 3. The top-ranked papers include a clinical guideline authored by Stefano Negrini et al., offering comprehensive insights into idiopathic scoliosis treatment. Additionally, Weinstein, SL et al.&#x0027;s publication delves into the pivotal role of braces in managing adolescent idiopathic scoliosis. Among the top 10 articles, two stand out as the most cited, garnering a total of 44 citations, while also boasting the highest Impact Factor (IF&#x2009;&#x003D;&#x2009;158.5). The remaining eight articles comprise a mix of research studies and clinical guidelines, collectively contributing to the evolving landscape of adolescent scoliosis treatment research.</p>
<table-wrap id="T4" position="float"><label>Table 4</label>
<caption><p>Representative articles in adolescent scoliosis treatment.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="center"/>
<col align="center"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="center"/>
<col align="center"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">No.</th>
<th valign="top" align="center">Count</th>
<th valign="top" align="center">Centrality</th>
<th valign="top" align="left">Title</th>
<th valign="top" align="left">Author</th>
<th valign="top" align="left">Journal (JCR &#x00AE;)</th>
<th valign="top" align="center">IF<xref ref-type="table-fn" rid="table-fn2"><sup>a</sup></xref></th>
<th valign="top" align="center">Published year</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">1</td>
<td valign="top" align="center">44</td>
<td valign="top" align="center">0.1</td>
<td valign="top" align="left">2016 SOSORT guidelines: orthopaedic and rehabilitation treatment of idiopathic scoliosis during growth</td>
<td valign="top" align="left">Stefano Negrini</td>
<td valign="top" align="left">N/A<xref ref-type="table-fn" rid="table-fn3"><sup>b</sup></xref></td>
<td valign="top" align="center">N/A<xref ref-type="table-fn" rid="table-fn3"><sup>b</sup></xref></td>
<td valign="top" align="center">2018</td>
</tr>
<tr>
<td valign="top" align="left">2</td>
<td valign="top" align="center">33</td>
<td valign="top" align="center">0.49</td>
<td valign="top" align="left">Effects of Bracing in Adolescents with Idiopathic Scoliosis</td>
<td valign="top" align="left">Weinstein, SL</td>
<td valign="top" align="left">MEDICINE, GENERAL &#x0026; INTERNAL (Q1)</td>
<td valign="top" align="center">158.5</td>
<td valign="top" align="center">2013</td>
</tr>
<tr>
<td valign="top" align="left">3</td>
<td valign="top" align="center">13</td>
<td valign="top" align="center">0.01</td>
<td valign="top" align="left">Anterior Spinal Growth Tethering for Skeletally Immature Patients with Scoliosis A Retrospective Look Two to Four Years Postoperatively</td>
<td valign="top" align="left">Newton, PO</td>
<td valign="top" align="left">ORTHOPEDICS in SCIE edition (Q1)</td>
<td valign="top" align="center">5.3</td>
<td valign="top" align="center">2018</td>
</tr>
<tr>
<td valign="top" align="left">4</td>
<td valign="top" align="center">12</td>
<td valign="top" align="center">0.03</td>
<td valign="top" align="left">Effect of Compliance Counseling on Brace Use and Success in Patients with Adolescent Idiopathic Scoliosis</td>
<td valign="top" align="left">Karol, LA</td>
<td valign="top" align="left">ORTHOPEDICS in SCIE edition (Q1)</td>
<td valign="top" align="center">5.3</td>
<td valign="top" align="center">2016</td>
</tr>
<tr>
<td valign="top" align="left">5</td>
<td valign="top" align="center">12</td>
<td valign="top" align="center">0.24</td>
<td valign="top" align="left">The efficacy of three-dimensional Schroth exercises in adolescent idiopathic scoliosis: a randomised controlled clinical trial</td>
<td valign="top" align="left">Kuru, T</td>
<td valign="top" align="left">REHABILITATION in SCIE edition (Q1)</td>
<td valign="top" align="center">3</td>
<td valign="top" align="center">2016</td>
</tr>
<tr>
<td valign="top" align="left">6</td>
<td valign="top" align="center">12</td>
<td valign="top" align="center">0.02</td>
<td valign="top" align="left">2011 SOSORT guidelines: Orthopedic and Rehabilitation treatment of idiopathic scoliosis during growth</td>
<td valign="top" align="left">Negrini S</td>
<td valign="top" align="left">N/A<xref ref-type="table-fn" rid="table-fn3"><sup>b</sup></xref></td>
<td valign="top" align="center">N/A<xref ref-type="table-fn" rid="table-fn3"><sup>b</sup></xref></td>
<td valign="top" align="center">2012</td>
</tr>
<tr>
<td valign="top" align="left">7</td>
<td valign="top" align="center">12</td>
<td valign="top" align="center">0.01</td>
<td valign="top" align="left">Brace treatment in adolescent idiopathic scoliosis: risk factors for failure-a literature review</td>
<td valign="top" align="left">El Hawary, R</td>
<td valign="top" align="left">ORTHOPEDICS in SCIE edition (Q1)</td>
<td valign="top" align="center">4.5</td>
<td valign="top" align="center">2019</td>
</tr>
<tr>
<td valign="top" align="left">8</td>
<td valign="top" align="center">11</td>
<td valign="top" align="center">0.03</td>
<td valign="top" align="left">Brace Success Is Related to Curve Type in Patients with Adolescent Idiopathic Scoliosis</td>
<td valign="top" align="left">Thompson, RM</td>
<td valign="top" align="left">ORTHOPEDICS in SCIE edition (Q1)</td>
<td valign="top" align="center">5.3</td>
<td valign="top" align="center">2017</td>
</tr>
<tr>
<td valign="top" align="left">9</td>
<td valign="top" align="center">10</td>
<td valign="top" align="center">0.02</td>
<td valign="top" align="left">Anterior Spinal Growth Modulation in Skeletally Immature Patients with Idiopathic Scoliosis A Comparison with Posterior Spinal Fusion at 2 to 5 Years Postoperatively</td>
<td valign="top" align="left">Newton, PO</td>
<td valign="top" align="left">ORTHOPEDICS in SCIE edition (Q1)</td>
<td valign="top" align="center">5.3</td>
<td valign="top" align="center">2020</td>
</tr>
<tr>
<td valign="top" align="left">10</td>
<td valign="top" align="center">9</td>
<td valign="top" align="center">0.08</td>
<td valign="top" align="left">Brace Wear Control of Curve Progression in Adolescent Idiopathic Scoliosis</td>
<td valign="top" align="left">Katz, DE</td>
<td valign="top" align="left">ORTHOPEDICS in SCIE edition (Q1)</td>
<td valign="top" align="center">5.3</td>
<td valign="top" align="center">2010</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="table-fn2"><label><sup>a</sup></label>
<p>The IF were obtained from the 2022 Journal Citation Reports (JCR).</p></fn>
<fn id="table-fn3"><label><sup>b</sup></label>
<p>Not applicable.</p></fn>
</table-wrap-foot>
</table-wrap>
</sec>
</sec>
<sec id="s4" sec-type="discussion"><label>4</label><title>Discussion</title>
<p>This article employs bibliometric analysis to elucidate the landscape of adolescent idiopathic scoliosis treatment, shedding light on its current status, focal areas, and emerging frontiers. Over the decade spanning from 2009 to 2019, the volume of publications in this domain remained relatively stable, with a discernible uptick observed from 2020 onwards, culminating in a peak in 2022.</p>
<p>These scholarly contributions predominantly find their place in journals specializing in scoliosis research, with Spine emerging as the primary outlet for dissemination. Notably, the United States and China, alongside various academic institutions, stand out as the leading contributors, showcasing both the highest publication output and significant influence in the realm of adolescent idiopathic scoliosis research literature. This comprehensive analysis provides valuable insights into the trajectory and geographical distribution of research efforts in this critical area of healthcare.</p>
<p>Newton, Peter O emerges as the most prolific author in this field, having published the largest number of papers. However, while there are some network links between authors, the overall collaboration is relatively limited and dispersed. This suggests a low level of collaboration among authors, albeit with scattered connections, indicative of a lack of consistent and stable partnerships. The current research hotspots in adolescent idiopathic scoliosis (AIS) focus on the relationship between the quality of life of AIS patients and various treatments, including Schroth exercises, vertebral body tethering, and growth modulation. There is also an emerging interest in fusion-related treatments, suggesting a possible new trend in future studies.</p>
<p>The United States leads in this field, holding the most central position with the highest number of publications. It is followed by China and Canada, with China and Turkey being the only developing countries among the top 10 in terms of publication count. This highlights the prominence of developed countries in AIS research, with their more robust healthcare infrastructure and research funding. At the same time, the presence of developing countries among the top contributors indicates a growing global interest in scoliosis treatment research. Developed countries, such as the United States, have better economic conditions than developing countries, and their residents enjoy higher access to insurance plans and better economic standards (<xref ref-type="bibr" rid="B7">7</xref>). In developed countries, patients with conditions like scoliosis may have greater access to healthcare services, including specialized treatments and participation in research studies. This increased access can lead to more active involvement in scoliosis research and publication activities compared to patients in developing countries, where healthcare resources and research opportunities may be more limited.</p>
<p>Therefore, we recommend that scholars from China and Turkey, especially the former, conduct more collaborative research with other developed countries. Most of the top 10 institutions are from the United States, and 60&#x0025; are universities. The network map of collaboration between institutions and authors is relatively fragmented. A growing body of evidence suggests that more inter-agency communication and collaboration between authors may be associated with higher research productivity and research quality (<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B9">9</xref>). Therefore, it is necessary to expand the network of cooperation between institutions and authors, especially with American universities.</p>
<p>Keyword clustering is a valuable technique for summarizing the core and hot spots within a research field. In the realm of AIS treatment, three prominent areas emerge as hot spots: Cobb angle measurement, the efficacy of non-surgical treatments, and the influencing factors affecting the success of brace treatment. At present, there are three main research directions in this field: interventions, influencing factors, and prognostic outcomes, but there are few studies on how to choose treatment methods based on different regions and different ethnic groups.</p>
<p>Notably, the Cobb angle is the most popular topic. The Cobb angle plays an important role in the diagnosis and treatment of adolescent idiopathic scoliosis and is not diagnosed until the Cobb angle exceeds 10&#x00B0; on standing spinal x-rays (<xref ref-type="bibr" rid="B10">10</xref>). Severe curvature of the Cobb angle &#x003E;50&#x00B0; should be surgical (<xref ref-type="bibr" rid="B11">11</xref>). Patients with immature bones with a Cobb angle of &#x2265;25&#x00B0; should use a brace to prevent or delay scoliosis progression. There is prognostic uncertainty about the Cobb angle of &#x003C;25&#x00B0; and the growth of remaining bone, and doctors use a watchful waiting strategy (<xref ref-type="bibr" rid="B12">12</xref>). At present, there are three main types of intervention for Cobb angle: surgical treatment, brace treatment, and conservative treatment. In the actual treatment process, the best treatment plan should be selected according to the actual situation of the patient. Other treatments, such as enriched bone marrow obtained by selective cell preservation technology, have a positive effect on the treatment of adolescent idiopathic scoliosis and the improvement of the Cobb angle. However, the intensity, duration, and duration of treatment need to be further verified. Researchers should conduct high-quality randomized controlled trials of different treatment regimens to provide the most effective treatment to improve the Cobb angle (<xref ref-type="bibr" rid="B7">7</xref>&#x2013;<xref ref-type="bibr" rid="B13">13</xref>). Other treatments, such as enriched bone marrow obtained by selective cell preservation technology, have a positive effect on the treatment of adolescent idiopathic scoliosis and the improvement of Cobb angle (<xref ref-type="bibr" rid="B14">14</xref>), but the intensity, duration, and duration of treatment need to be further validated. Researchers should conduct high-quality randomized controlled trials of different treatment options to provide the most effective treatment to improve the Cobb angle.</p>
<p>Another hot topic is the Efficacy of non-surgical treatment of AIS. However, due to the high risk and high cost of surgical treatment, non-surgical treatment has gradually become the primary choice, especially for patients with mild initial scoliosis, exercise therapy is a more effective and preventive method for scoliosis (<xref ref-type="bibr" rid="B15">15</xref>). At present, there are two types of exercise therapy, one is general exercise therapy, which mainly includes lower-intensity stretching exercises and strength training, which can stabilize the condition and alleviate the condition to a certain extent (<xref ref-type="bibr" rid="B16">16</xref>). The other approach is Physiotherapy Scoliosis Specific Exercise (PSSE), which focuses on preventing the development of scoliosis and is recommended by the SOSORT Association as the first step in the treatment of mild AIS (<xref ref-type="bibr" rid="B17">17</xref>). Through many high-quality studies, it has been found that PSSE is superior to general exercise therapy in correcting Cobb angle in AIS patients, but PSSE also has its disadvantages, especially in improving deformity, its efficacy is not as good as that of brace therapy, but compared with brace treatment, PSSE has obvious advantages in relieving pain and improving patients&#x0027; mental health (<xref ref-type="bibr" rid="B18">18</xref>).</p>
<p>The third hotspot is the factors affecting the success of brace treatment, AIS is a relatively common disease, and there are two main treatment methods: surgical treatment and non-surgical treatment. Brace therapy has been shown to be one of the most effective non-surgical treatments (<xref ref-type="bibr" rid="B19">19</xref>). However, the success of brace therapy is affected by a variety of factors, among which adherence is the most important factor, and maintaining a high degree of adherence is the basis for the success of brace therapy (<xref ref-type="bibr" rid="B20">20</xref>). Increasing patient brace compliance during treatment can improve treatment outcomes (<xref ref-type="bibr" rid="B21">21</xref>). The length of time the brace is worn is also an important factor. It has been reported that factors associated with bracing may interfere with various aspects of a patient&#x0027;s health, negatively impacting the patient&#x0027;s daily life (<xref ref-type="bibr" rid="B22">22</xref>). Therefore, wearing a brace for a longer period each day may lead to a further decline in the quality of life of patients with AIS, which in turn affects patient compliance and thus disease progression (<xref ref-type="bibr" rid="B23">23</xref>). In addition to this, the main factors include the patient&#x0027;s low skeletal maturity and the initial Cobb angle &#x003E;30&#x00B0; (<xref ref-type="bibr" rid="B24">24</xref>).</p>
<p>The emergence of keywords and the trend of their changes can reflect the development history and frontier of research. The process of this study can be divided into three processes. This study summarizes two research trends. The relationship between the first curvature and prognosis. To date, the effectiveness of school-age screening remains controversial in relevant studies, and it is uncertain what curvature can progress after diagnosis until the stage where treatment is needed (<xref ref-type="bibr" rid="B25">25</xref>). In response to this, research on the prognosis of adolescent idiopathic scoliosis has attracted increasing attention to guide the initiation of treatment (<xref ref-type="bibr" rid="B26">26</xref>). For brace therapy in particular, different curvatures have an important impact on the success of brace therapy (<xref ref-type="bibr" rid="B27">27</xref>). Future studies need to be carefully designed to explore the relationship between different curvatures and prognosis. Second, research on the etiology of adolescent idiopathic scoliosis. Current theories regarding the etiology of adolescent idiopathic scoliosis include genetic, metabolic, biomechanical, and environmental theories (<xref ref-type="bibr" rid="B28">28</xref>). At present, the pathogenesis of adolescent idiopathic scoliosis is mainly biomechanical, but there is a lack of accepted mechanistic theories (<xref ref-type="bibr" rid="B4">4</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B26">26</xref>, <xref ref-type="bibr" rid="B28">28</xref>&#x2013;<xref ref-type="bibr" rid="B30">30</xref>). In terms of genetic factors, although genetic factors are currently thought to play an important role in adolescent idiopathic scoliosis, this factor has considerable specificity (<xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B32">32</xref>). Current research into the etiology of adolescent idiopathic scoliosis is complicated by the suspicion that it is not caused by a single cause, but by the interaction of multiple causes (<xref ref-type="bibr" rid="B4">4</xref>, <xref ref-type="bibr" rid="B30">30</xref>&#x2013;<xref ref-type="bibr" rid="B34">34</xref>). For adolescent idiopathic scoliosis, a better understanding of the underlying etiological mechanisms associated with it can lead to a better diagnosis of the disease and accurate prediction of deformity progression, helping patients achieve the best clinical outcomes (<xref ref-type="bibr" rid="B35">35</xref>).</p>
<p>This study carried out a comprehensive analysis focusing on various aspects such as the volume of annual publications, journal contributions, contributing countries, institutions, and authors, as well as keyword clustering and prominence. Through this analysis, we have charted the trends in annual publication volumes over the past fifteen years and identified the journals with the highest number of contributions. The findings suggest that enhanced collaboration among different countries, institutions, and authors is crucial. By examining keyword clustering and prominence, we have pinpointed current research hotspots and anticipated future research directions.</p>
<p>This study acknowledges certain limitations. Firstly, the search was confined to publications from the WoSCC database, excluding literature from other significant databases such as PubMed or Embase relevant to adolescent idiopathic scoliosis treatment. While each database has unique characteristics, combining papers from multiple sources can offer a more thorough understanding of the topic. While the WoSCC database is highly respected and contains prestigious academic journals, it&#x0027;s essential to consider literature from additional sources to ensure a comprehensive review. Secondly, due to constraints with CiteSpace software, this study only encompasses English articles published within the last fifteen years, potentially missing out on valuable research published in other languages or before the specified timeframe. This limitation might impact the study&#x0027;s breadth and applicability. To mitigate these limitations, future research could expand the search to encompass multiple databases and languages. Additionally, employing alternative bibliometric analysis tools could enhance the comprehensiveness of the review of adolescent idiopathic scoliosis treatment literature.</p>
</sec>
<sec id="s5" sec-type="conclusions"><label>5</label><title>Conclusion</title>
<p>The study you&#x0027;re referring to analyzed a total of 1,002 English-language articles focused on the treatment of AIS from 2009 to 2022. It observed that while publication volume remained low and stable until 2020, there was a noticeable increase starting in 2021, with the highest number of publications recorded in 2022. This trend suggests a growing interest and development in the field of AIS treatment during these years. The analysis highlighted that the United States led in terms of contributions, with significant input from both Nanjing University and Peter O. Newton, identified as the most prolific institution and author, respectively. The journal &#x201C;Spine&#x201D; was noted as the primary publication venue for research in this area. Research hotspots identified include the Cobb angle, the efficacy of non-surgical treatments for AIS, and factors influencing the success of brace treatment. These focus areas have been crucial in understanding and advancing treatment strategies for AIS. The paper also points out emerging trends in the research, particularly the relationships between spinal curvature and patient prognosis, as well as the underlying causes of AIS. Investigating these areas could lead to innovative treatment approaches and more tailored care plans, potentially improving outcomes for those with AIS. The study underscores the importance of translating these research findings into clinical practice and serves as a valuable resource for scholars aiming to further explore AIS treatment strategies. This kind of research is vital not only for expanding scientific understanding but also for enhancing practical applications that benefit patients directly.</p>
</sec>
</body>
<back>
<sec id="s6" sec-type="author-contributions"><title>Author contributions</title>
<p>XZ: Conceptualization, Formal Analysis, Methodology, Validation, Visualization, Writing &#x2013; original draft, Writing &#x2013; review &#x0026; editing. WH: Visualization, Writing &#x2013; review &#x0026; editing. SG: Visualization, Writing &#x2013; review &#x0026; editing. MJ: Formal Analysis, Writing &#x2013; review &#x0026; editing. LL: Conceptualization, Writing &#x2013; review &#x0026; editing. LY: Methodology, Visualization, Writing &#x2013; review &#x0026; editing.</p>
</sec>
<sec id="s7" sec-type="funding-information"><title>Funding</title>
<p>The author(s) declare financial support was received for the research, authorship, and/or publication of this article. 2023 Shandong Provincial Traditional Chinese Medicine Science and Technology Project (Q-2023034), 2022 Shandong Provincial Traditional Chinese Medicine Science and Technology Project (Z-2022023), 2022 Weifang Science and Technology Development Plan (2022YX015).</p>
</sec>
<sec id="s8" sec-type="COI-statement"><title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="s12" sec-type="ai-statement"><title>Generative AI statement</title>
<p>The author(s) declare that no Generative AI was used in the creation of this manuscript.</p>
</sec>
<sec id="s10" sec-type="disclaimer"><title>Publisher&#x0027;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<fn-group>
<title>Abbreviations</title>
<fn fn-type="abbr" id="ab001"><p>WOSCC, Web of Science Core Collection; AIS, adolescent idiopathic scoliosis.</p></fn>
</fn-group>
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