AUTHOR=Zaubitzer Lena , Kotzur Anja , Hegemann Stefan , Rotter Nicole , Schell Angela 

TITLE=Assessing long-term, vestibulotoxic side effects after gentamicin therapy in neonatal sepsis or infection using video head impulse test

JOURNAL=Frontiers in Pediatrics

VOLUME=Volume 12 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2024.1366074

DOI=10.3389/fped.2024.1366074

ISSN=2296-2360

ABSTRACT=Question: Does gentamicin therapy in children with neonatal sepsis or infection lead to persistent vestibulotoxicity? Findings: In a single-center, prospective cross-sectional study video head impulse test (VHIT) was performed to evaluate vestibular function in 23 children aged 3-7 years at least three years after intravenous gentamicin therapy for neonatal sepsis or infection.Although eleven children showed abnormal results in vestibular testing, they did not present with a clinically significant vestibular hypofunction or delayed motoric development.VHIT can serve as a sensitive investigation method for the screening of posttherapeutic vestibulotoxic side effects after gentamicin therapy in children.