AUTHOR=Hu Shaohua , Zhao Zhenli , Wan Zhisheng , Bu Weizhen , Chen Songqiang , Lu Yiqun 

TITLE=Chemotherapy Combined With Surgery in a Case With Metanephric Adenoma

JOURNAL=Frontiers in Pediatrics

VOLUME=Volume 10 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2022.847864

DOI=10.3389/fped.2022.847864

ISSN=2296-2360

ABSTRACT=Background: Metanephric adenoma is an extremely rare renal neoplasm, especially in pediatrics. Chemotherapy combined with surgery in metanephric adenoma has not been reported. Methods: We describe a case of metanephric adenoma in a child less than 2 years old, which were treated by chemotherapy combined with surgery. Results: Nephron sparing surgery was performed after regular chemotherapy, and the pathological result was metanephric adenoma. Conclusions: Pediatric metanephric adenoma is extremely rare, the clinical manifestations and imaging examinations lack specificity. Nephron sparing surgery is recommended as the preferred treatment for metanephric adenoma. Long-term follow-up and more in-depth molecular genetic research are still needed to determine the benign or malignant of metanephric adenoma and whether chemotherapy drugs have an effect on it.