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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Pediatr.</journal-id>
<journal-title>Frontiers in Pediatrics</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Pediatr.</abbrev-journal-title>
<issn pub-type="epub">2296-2360</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fped.2021.790285</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Pediatrics</subject>
<subj-group>
<subject>Correction</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Corrigendum: Age-Related Differences in the Expression of Most Relevant Mediators of SARS-CoV-2 Infection in Human Respiratory and Gastrointestinal Tract</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name><surname>Berni Canani</surname> <given-names>Roberto</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
<xref ref-type="aff" rid="aff4"><sup>4</sup></xref>
<xref ref-type="corresp" rid="c001"><sup>&#x0002A;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/217284/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Comegna</surname> <given-names>Marika</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="aff" rid="aff5"><sup>5</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/656480/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Paparo</surname> <given-names>Lorella</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/583171/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Cernera</surname> <given-names>Gustavo</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="aff" rid="aff5"><sup>5</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/883074/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Bruno</surname> <given-names>Cristina</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/679473/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Strisciuglio</surname> <given-names>Caterina</given-names></name>
<xref ref-type="aff" rid="aff6"><sup>6</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/570481/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Zollo</surname> <given-names>Immacolata</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="aff" rid="aff5"><sup>5</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Gravina</surname> <given-names>Antonietta Gerarda</given-names></name>
<xref ref-type="aff" rid="aff7"><sup>7</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/1117567/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Miele</surname> <given-names>Erasmo</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/566202/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Cantone</surname> <given-names>Elena</given-names></name>
<xref ref-type="aff" rid="aff8"><sup>8</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Gennarelli</surname> <given-names>Nicola</given-names></name>
<xref ref-type="aff" rid="aff9"><sup>9</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Nocerino</surname> <given-names>Rita</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/678993/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Carucci</surname> <given-names>Laura</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/977730/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Giglio</surname> <given-names>Veronica</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Amato</surname> <given-names>Felice</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="aff" rid="aff5"><sup>5</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/637414/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Castaldo</surname> <given-names>Giuseppe</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="aff" rid="aff5"><sup>5</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/656585/overview"/>
</contrib>
</contrib-group>
<aff id="aff1"><sup>1</sup><institution>Department of Translational Medical Science, University of Naples Federico II</institution>, <addr-line>Naples</addr-line>, <country>Italy</country></aff>
<aff id="aff2"><sup>2</sup><institution>CEINGE-Biotecnologie Avanzate s.c.ar.l., University of Naples Federico II</institution>, <addr-line>Naples</addr-line>, <country>Italy</country></aff>
<aff id="aff3"><sup>3</sup><institution>European Laboratory for the Investigation of Food-Induced Diseases, University of Naples Federico II</institution>, <addr-line>Naples</addr-line>, <country>Italy</country></aff>
<aff id="aff4"><sup>4</sup><institution>Task Force for Microbiome Studies, University of Naples Federico II</institution>, <addr-line>Naples</addr-line>, <country>Italy</country></aff>
<aff id="aff5"><sup>5</sup><institution>Department of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II</institution>, <addr-line>Naples</addr-line>, <country>Italy</country></aff>
<aff id="aff6"><sup>6</sup><institution>Department of Woman, Child and General and Specialistic Surgery, University of Campania &#x0201C;Luigi Vanvitelli&#x0201D;</institution>, <addr-line>Naples</addr-line>, <country>Italy</country></aff>
<aff id="aff7"><sup>7</sup><institution>Division of Hepatogastroenterology, Department of Precision Medicine, University of Campania &#x0201C;Luigi Vanvitelli&#x0201D;</institution>, <addr-line>Naples</addr-line>, <country>Italy</country></aff>
<aff id="aff8"><sup>8</sup><institution>Department of Neuroscience, Reproductive and Odontostomatological Sciences, Ear, Nose and Throat (ENT) Section, University of Naples Federico II</institution>, <addr-line>Naples</addr-line>, <country>Italy</country></aff>
<aff id="aff9"><sup>9</sup><institution>Department of Clinical Medicine and Surgery, University of Naples Federico II</institution>, <addr-line>Naples</addr-line>, <country>Italy</country></aff>
<author-notes>
<corresp id="c001">&#x0002A;Correspondence: Roberto Berni Canani <email>berni&#x00040;unina.it</email></corresp>
<fn fn-type="edited-by"><p>Approved by: Frontiers Editorial Office, Frontiers Media SA, Switzerland</p></fn>
<fn fn-type="other" id="fn001"><p>This article was submitted to Pediatric Gastroenterology, Hepatology and Nutrition, a section of the journal Frontiers in Pediatrics</p></fn></author-notes>
<pub-date pub-type="epub">
<day>10</day>
<month>11</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="collection">
<year>2021</year>
</pub-date>
<volume>9</volume>
<elocation-id>790285</elocation-id>
<history>
<date date-type="received">
<day>06</day>
<month>10</month>
<year>2021</year>
</date>
<date date-type="accepted">
<day>15</day>
<month>10</month>
<year>2021</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x000A9; 2021 Berni Canani, Comegna, Paparo, Cernera, Bruno, Strisciuglio, Zollo, Gravina, Miele, Cantone, Gennarelli, Nocerino, Carucci, Giglio, Amato and Castaldo.</copyright-statement>
<copyright-year>2021</copyright-year>
<copyright-holder>Berni Canani, Comegna, Paparo, Cernera, Bruno, Strisciuglio, Zollo, Gravina, Miele, Cantone, Gennarelli, Nocerino, Carucci, Giglio, Amato and Castaldo</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license> </permissions>
<related-article id="RA1" related-article-type="corrected-article" journal-id="Front Pediatr" journal-id-type="nlm-ta" vol="9" page="697390" xlink:href="10.3389/fped.2021.697390" ext-link-type="doi">A Corrigendum on <article-title>Age-Related Differences in the Expression of Most Relevant Mediators of SARS-CoV-2 Infection in Human Respiratory and Gastrointestinal Tract</article-title> by Berni Canani, R., Comegna, M., Paparo, L., Cernera, G., Bruno, C., Strisciuglio, C., Zollo, I., Gravina, A. G., Miele, E., Cantone, E., Gennarelli, N., Nocerino, R., Carucci, L., Giglio, V., Amato, F., and Castaldo, G. (2021). Front. Pediatr. 9:697390. doi: <object-id>10.3389/fped.2021.697390</object-id></related-article> <kwd-group>
<kwd>COVID-19</kwd>
<kwd>angiotensin-converting enzyme 2</kwd>
<kwd>transmembrane serine protease-2</kwd>
<kwd>neuropilin-1</kwd>
<kwd>healthy subjects</kwd>
</kwd-group>
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<fig-count count="2"/>
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<equation-count count="0"/>
<ref-count count="0"/>
<page-count count="2"/>
<word-count count="867"/>
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</front>
<body>
<p>In the original article, there was a mistake in the order of <xref ref-type="fig" rid="F1">Figures 1</xref> and <xref ref-type="fig" rid="F2">2</xref> as published. The figures are given in the correct order below.</p>
<fig id="F1" position="float">
<label>Figure 1</label>
<caption><p>qPCR analysis of Angiotensin I Converting Enzyme (<italic>ACE1</italic>), Angiotensin II Converting Enzyme (<italic>ACE2</italic>), Transmembrane Serine Protease 2 (<italic>TMPRSS2</italic>), and Neuropilin-1 <italic>(NRP1</italic>) genes in nasal epithelium from children and adult subjects. Comparative expression of <italic>ACE1, ACE2, TMPRSS2</italic>, and <italic>NRP1</italic> in nasal epithelium of children (<italic>n</italic> = 15) and adult subjects (<italic>n</italic> = 15). Data analysis was performed using the comparative threshold cycle (CT) method and expressed as 2<sup>&#x02227;</sup>-delta CT. Gene expression was normalized against the expression of the reference gene hypoxanthine phosphoribosyltransferase 1 (<italic>HPRT</italic>). Data are expressed as median &#x000B1; SD, the X in the bars indicates mean values. <italic>P</italic>-value are reported in the graphs; significant differences are indicated as <sup>&#x0002A;</sup><italic>p</italic> &#x0003C; 0.01; <sup>&#x0002A;&#x0002A;</sup><italic>p</italic> &#x0003C; 0.005.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fped-09-790285-g0001.tif"/>
</fig>
<fig id="F2" position="float">
<label>Figure 2</label>
<caption><p>qPCR analysis of Angiotensin I Converting Enzyme (<italic>ACE1</italic>), Angiotensin II Converting Enzyme (<italic>ACE2</italic>), Transmembrane Serine Protease 2 (<italic>TMPRSS2</italic>), and Neuropilin-1 (<italic>NRP1</italic>) genes in small intestine from children and adult subjects. Comparative expression of <italic>ACE1, ACE2, TMPRSS2</italic>, and <italic>NRP1</italic> in small intestine of children (<italic>n</italic> = 15) and adult subjects (<italic>n</italic> = 15). Data analysis was performed using the comparative threshold cycle (CT) method and expressed as 2<sup>&#x02227;</sup>-delta CT. Gene expression was normalized against the expression of the reference gene hypoxanthine phosphoribosyltransferase 1 (<italic>HPRT</italic>). Data are expressed as median &#x000B1; SD, the X in the bars indicates mean values. <italic>P</italic>-value are reported in the graphs; significant differences are indicated as <sup>&#x0002A;</sup><italic>p</italic> &#x0003C; 0.01; <sup>&#x0002A;&#x0002A;</sup><italic>p</italic> &#x0003C; 0.005.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fped-09-790285-g0002.tif"/>
</fig>
<p>The authors apologize for the error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.</p>
<sec sec-type="disclaimer" id="s1">
<title>Publisher&#x00027;s Note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p></sec> </body>
</article>
