AUTHOR=O'Connor Thomas G. , Williams Jason , Blair Clancy , Gatzke-Kopp Lisa M. , Francis Lori , Willoughby Michael T. 
  
TITLE=Predictors of Developmental Patterns of Obesity in Young Children
  
JOURNAL=Frontiers in Pediatrics
  
VOLUME=Volume 8 - 2020
  
YEAR=2020
  
URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2020.00109
  
DOI=10.3389/fped.2020.00109
  
ISSN=2296-2360
  
ABSTRACT=Introduction: The current study characterizes longitudinal patterns in obesity and their prediction from developmental programming and social determinant hypotheses of childhood obesity.
Materials and Methods: The data are based on the Family Life Project, a prospective longitudinal study of 1,292 families recruited from low-income, racially diverse, rural communities in Pennsylvania and North Carolina.  Prenatal, perinatal, and postnatal risks for childhood obesity were collected from 2 months of age; in-person assessments of child growth were used to identity obesity on multiple occasions from 24 to 90 months of age. 
Results: Two major novel findings emerged.  First, longitudinal analyses identified four distinct obesity development profiles: stable obesity, later-onset obesity, moderate/declining obesity, and non-obese; these groups had distinct risk profiles.  Second, prediction analyses favored developmental programming explanations for obesity, including evidence even in early childhood that both low- and high birth weight was associated with stable obesity.  There was no indication that pre- and perinatal and postnatal factors predicted obesity differently in non-minority and minority children.
Discussion: Factors derived from the developmental programming model of obesity overlapped with, but predicted early onset obesity independently from, risks associated with social determinant models of obesity.