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<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Pain Res.</journal-id>
<journal-title>Frontiers in Pain Research</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Pain Res.</abbrev-journal-title>
<issn pub-type="epub">2673-561X</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpain.2023.1205253</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Pain Research</subject>
<subj-group>
<subject>Editorial</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Editorial: Insights in musculoskeletal pain: 2022</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes"><name><surname>Sato</surname><given-names>Tatiana de Oliveira</given-names></name>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref><uri xlink:href="https://loop.frontiersin.org/people/1940677/overview"/></contrib>
</contrib-group>
<aff><addr-line>Physical Therapy Department</addr-line>, <institution>Federal University of S&#x00E3;o Carlos</institution>, <addr-line>S&#x00E3;o Carlos</addr-line>, <country>Brazil</country></aff>
<author-notes>
<fn fn-type="edited-by"><p><bold>Edited and Reviewed by:</bold>Ke Ren, University of Maryland, United States</p></fn>
<corresp id="cor1"><label>&#x002A;</label><bold>Correspondence:</bold> Tatiana de Oliveira Sato <email>tatisato@ufscar.br</email></corresp>
</author-notes>
<pub-date pub-type="epub"><day>05</day><month>05</month><year>2023</year></pub-date>
<pub-date pub-type="collection"><year>2023</year></pub-date>
<volume>4</volume><elocation-id>1205253</elocation-id>
<history>
<date date-type="received"><day>13</day><month>04</month><year>2023</year></date>
<date date-type="accepted"><day>20</day><month>04</month><year>2023</year></date>
</history>
<permissions>
<copyright-statement>&#x00A9; 2023 Sato.</copyright-statement>
<copyright-year>2023</copyright-year><copyright-holder>Sato</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<kwd-group>
<kwd>chronic pain</kwd>
<kwd>knee ostearthritis</kwd>
<kwd>type 2 diabetes</kwd>
<kwd>osteoporotic vertebral body fracture</kwd>
<kwd>mechanical stimulation</kwd>
</kwd-group><counts>
<fig-count count="0"/>
<table-count count="0"/><equation-count count="0"/><ref-count count="0"/><page-count count="0"/><word-count count="0"/></counts><custom-meta-wrap><custom-meta><meta-name>section-at-acceptance</meta-name><meta-value>Musculoskeletal Pain</meta-value></custom-meta></custom-meta-wrap>
</article-meta>
</front>
<body>
<p>Editorial on the Research Topic <ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/research-topics/40024/insights-in-musculoskeletal-pain-2022">Insights in musculoskeletal pain: 2022</ext-link></p>
<p>Musculoskeletal pain is one of the leading causes of disability and healthcare costs worldwide. Many people suffer daily from this health condition, affecting their quality of life and work ability. Several studies document the causes and consequences of musculoskeletal pain, and others look at the best treatment for musculoskeletal pain.</p>
<p>In this special issue, <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fpain.2022.1038269">Hettchen et al.</ext-link> from the Friedrich-Alexander University of Erlangen-N&#x00FC;rnberg (Erlangen, Germany), discuss the effects of an orthosis on women with chronic low back pain with osteoporotic vertebral fractures in a randomized controlled trial. The authors found evidence of the effectiveness of spinal orthosis, reducing back pain, disability, kyphosis angle and improving trunk strength. Thus, this active strengthening spinal orthosis has shown positive effects for women with low back pain associated with osteoporotic vertebral fractures.</p>
<p><ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fpain.2022.1082252">Overton et al.</ext-link> from the University of Otago (Dunedin, New Zealand), showed in a longitudinal study of New Zealand patients with knee osteoarthritis, that activity-related pain predicted future pain and functional outcomes in patients with osteoarthritis after two and nine weeks. These findings highlight the importance of assessing activity-related pain using movement-evoked pain and physical activity sensitivity to predict future pain in this patients.</p>
<p><ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fendo.2023.1100874">Jin et al.</ext-link> from Beijing Jishuitan Hospital (Beijing, China) used a Mendelian randomization analysis to assess the causal association between intervertebral disc degeneration and type 2 diabetes mellitus. Their interesting findings showed that patients with type 2 diabetes mellitus were at increased risk of developing intervertebral disc degeneration and could offer new strategies for the management and prevention of low back pain in patients with diabetes.</p>
<p>Finally, <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/fpain.2023.1114633">Baxter et al.</ext-link> from Pain Care Labs (United States) described the effects of multimodal mechanical stimulation therapy on acute and chronic low back pain in a phase I clinical pilot investigation, with promising results in drug-free pain relief.</p>
<p>We hope you enjoy this special issue and that it will be useful and bring new insights to your clinical practice and research.</p>
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<sec id="s1" sec-type="author-contributions"><title>Author contributions</title>
<p>The author confirms being the sole contributor of this work and has approved it for publication.</p>
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<sec id="s2" sec-type="COI-statement"><title>Conflict of interest</title>
<p>The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
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<sec id="s3" sec-type="disclaimer"><title>Publisher&#x0027;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
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