<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.3 20070202//EN" "journalpublishing.dtd">
<article article-type="review-article" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xml:lang="EN"><?covid-19-tdm?>
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Oral. Health</journal-id>
<journal-title>Frontiers in Oral Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Oral. Health</abbrev-journal-title>
<issn pub-type="epub">2673-4842</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/froh.2023.1270959</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Oral Health</subject>
<subj-group>
<subject>Mini Review</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Ultraviolet disinfection (UV-D) robots: bridging the gaps in dentistry</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Pandya</surname><given-names>Visha Shailesh</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref><uri xlink:href="https://loop.frontiersin.org/people/1323837/overview"/>
<role content-type="https://credit.niso.org/contributor-roles/conceptualization/"/>
<role content-type="https://credit.niso.org/contributor-roles/methodology/"/>
<role content-type="https://credit.niso.org/contributor-roles/project-administration/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author"><name><surname>Morsy</surname><given-names>Mohamed S.M.</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<role content-type="https://credit.niso.org/contributor-roles/methodology/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author"><name><surname>Hassan</surname><given-names>Ali Abdel-Halim Abdel-Azim</given-names></name>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/></contrib>
<contrib contrib-type="author"><name><surname>Alshawkani</surname><given-names>Hamed A.</given-names></name>
<xref ref-type="aff" rid="aff4"><sup>4</sup></xref>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/"/>
</contrib>
<contrib contrib-type="author"><name><surname>Sindi</surname><given-names>Abdulelah Sameer</given-names></name>
<xref ref-type="aff" rid="aff5"><sup>5</sup></xref>
<role content-type="https://credit.niso.org/contributor-roles/formal-analysis/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author"><name><surname>Mattoo</surname><given-names>Khurshid A.</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<role content-type="https://credit.niso.org/contributor-roles/methodology/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Mehta</surname><given-names>Vini</given-names></name>
<xref ref-type="aff" rid="aff6"><sup>6</sup></xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref>
<role content-type="https://credit.niso.org/contributor-roles/conceptualization/"/>
<role content-type="https://credit.niso.org/contributor-roles/methodology/"/>
<role content-type="https://credit.niso.org/contributor-roles/project-administration/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author"><name><surname>Mathur</surname><given-names>Ankita</given-names></name>
<xref ref-type="aff" rid="aff6"><sup>6</sup></xref>
<role content-type="https://credit.niso.org/contributor-roles/methodology/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Meto</surname><given-names>Aida</given-names></name>
<xref ref-type="aff" rid="aff6"><sup>6</sup></xref>
<xref ref-type="aff" rid="aff7"><sup>7</sup></xref>
<xref ref-type="aff" rid="aff8"><sup>8</sup></xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref><uri xlink:href="https://loop.frontiersin.org/people/1365719/overview" />
<role content-type="https://credit.niso.org/contributor-roles/formal-analysis/"/>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/"/></contrib>
</contrib-group>
<aff id="aff1"><label><sup>1</sup></label><institution>Department of Public Health Dentistry, Vaidik Dental College &#x0026; Research Centre, Dadra and Nagar Haveli and Daman and Diu</institution>, <country>India</country></aff>
<aff id="aff2"><label><sup>2</sup></label><institution>Department of Prosthetic Dental Sciences, College of Dentistry, Jazan University</institution>, <addr-line>Jazan</addr-line>, <country>Saudi Arabia</country></aff>
<aff id="aff3"><label><sup>3</sup></label><institution>Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University</institution>, <addr-line>Jazan</addr-line>, <country>Saudi Arabia</country></aff>
<aff id="aff4"><label><sup>4</sup></label><institution>Department of Restorative Dental Science, College of Dentistry, Jazan University</institution>, <addr-line>Jazan</addr-line>, <country>Saudi Arabia</country></aff>
<aff id="aff5"><label><sup>5</sup></label><institution>Department of Restorative Dental Sciences, College of Dentistry, King Khalid University</institution>, <addr-line>Abha</addr-line>, <country>Saudi Arabia</country></aff>
<aff id="aff6"><label><sup>6</sup></label><institution>Department of Dental Research Cell, Dr. D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth</institution>, <addr-line>Pune</addr-line>, <country>India</country></aff>
<aff id="aff7"><label><sup>7</sup></label><institution>Department of Dentistry, Faculty of Dental Sciences, University of Aldent</institution>, <addr-line>Tirana</addr-line>, <country>Albania</country></aff>
<aff id="aff8"><label><sup>8</sup></label><institution>Clinical Microbiology, School of Dentistry, University of Modena and Reggio Emilia</institution>, <addr-line>Modena</addr-line>, <country>Italy</country></aff>
<author-notes>
<fn fn-type="edited-by"><p><bold>Edited by:</bold> Luis Felipe Carvalho, Universidade de Taubat&#x00E9;, Brazil</p></fn>
<fn fn-type="edited-by"><p><bold>Reviewed by:</bold> Jianhui Liu, Harvard University, United States</p></fn>
<corresp id="cor1"><label>&#x002A;</label><bold>Correspondence:</bold> Vini Mehta <email>vini.mehta@statsense.in</email> Aida Meto <email>aidameto@yahoo.com</email></corresp>
<fn fn-type="other" id="fn001"><p><bold>Abbreviations</bold> UV-D, ultraviolet disinfectant; UVGI, ultraviolet germicidal irradiation; HAI, healthcare-associated infection; MRSA, methicillin-resistant Staphylococcus aureus; VRE, vancomycin-resistant Enterococci; UV, ultraviolet; LPM, low-pressure mercury; SLAM, simultaneous localization and mapping; C diff., clostridioides difficile; VRE, vancomycin-resistant enterococci; CRE, carbapenem-resistant enterobacterales; MRSA, methicillin-resistant Staphylococcus aureus; AIDBOT, artificial intelligence disinfection roBOT; OMS robot, oral and maxillofacial surgery robot; DOF, degrees of freedom; OAW, orthodontic archwire; CARs, catalytic antimicrobial robots, MR-safe, magnetic resonance safe; 3D, 3-dimensional; TBC, total bacterial count, AI, artificial intelligence; W, watt; QACs, quaternary ammonium compounds; SARS, severe acute respiratory syndrome.</p></fn>
</author-notes>
<pub-date pub-type="epub"><day>01</day><month>11</month><year>2023</year></pub-date>
<pub-date pub-type="collection"><year>2023</year></pub-date>
<volume>4</volume><elocation-id>1270959</elocation-id>
<history>
<date date-type="received"><day>01</day><month>08</month><year>2023</year></date>
<date date-type="accepted"><day>18</day><month>10</month><year>2023</year></date>
</history>
<permissions>
<copyright-statement>&#x00A9; 2023 Pandya, Morsy, Hassan, Alshawkani, Sindi, Mattoo, Mehta, Mathur and Meto.</copyright-statement>
<copyright-year>2023</copyright-year><copyright-holder>Pandya, Morsy, Hassan, Alshawkani, Sindi, Mattoo, Mehta, Mathur and Meto</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<abstract>
<p>Maintaining a microbe-free environment in healthcare facilities has become increasingly crucial for minimizing virus transmission, especially in the wake of recent epidemics like COVID-19. To meet the urgent need for ongoing sterilization, autonomous ultraviolet disinfection (UV-D) robots have emerged as vital tools. These robots are gaining popularity due to their automated nature, cost advantages, and ability to instantly disinfect rooms and workspaces without relying on human labor. Integrating disinfection robots into medical facilities reduces infection risk, lowers conventional cleaning costs, and instills greater confidence in patient safety. However, UV-D robots should complement rather than replace routine manual cleaning. To optimize the functionality of UV-D robots in medical settings, additional hospital and device design modifications are necessary to address visibility challenges. Achieving seamless integration requires more technical advancements and clinical investigations across various institutions. This mini-review presents an overview of advanced applications that demand disinfection, highlighting their limitations and challenges. Despite their potential, little comprehensive research has been conducted on the sterilizing impact of disinfection robots in the dental industry. By serving as a starting point for future research, this review aims to bridge the gaps in knowledge and identify unresolved issues. Our objective is to provide an extensive guide to UV-D robots, encompassing design requirements, technological breakthroughs, and in-depth use in healthcare and dentistry facilities. Understanding the capabilities and limitations of UV-D robots will aid in harnessing their potential to revolutionize infection control practices in the medical and dental fields.</p>
</abstract>
<kwd-group>
<kwd>artificial intelligence</kwd>
<kwd>COVID-19</kwd>
<kwd>disinfection robot</kwd>
<kwd>dentistry</kwd>
<kwd>robot sterilization</kwd>
<kwd>ultraviolet disinfection</kwd>
</kwd-group>
<contract-sponsor id="cn001">The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.</contract-sponsor>
<counts>
<fig-count count="1"/>
<table-count count="2"/><equation-count count="0"/><ref-count count="67"/><page-count count="0"/><word-count count="0"/></counts><custom-meta-wrap><custom-meta><meta-name>section-at-acceptance</meta-name><meta-value>Preventive Dentistry</meta-value></custom-meta></custom-meta-wrap>
</article-meta>
</front>
<body>
<sec id="s1" sec-type="intro"><label>1.</label><title>Introduction</title>
<p>The healthcare and its associated sectors are one of the fastest-growing industries globally. In a health care facility, microorganisms persist on an inanimate surface for a longer period causing transmission of infectious diseases (bacterial, viral and fungal) through direct or indirect contact (<xref ref-type="bibr" rid="B1">1</xref>, <xref ref-type="bibr" rid="B2">2</xref>). Novel techniques are essential due to increase in the transmission and fatality rate of viral disease, as one seen during a COVID-19 pandemic that was known to last for 28 days under controlled laboratory environments (<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B4">4</xref>). This calls for making the eradication of all microorganisms on seemingly non infected areas a crucial component of disinfection. Disinfection is a process that halts the dissemination of all infectious agents by inactivating them and preventing their transmission (<xref ref-type="bibr" rid="B5">5</xref>). Several hospital settings like wards and theatres need to be cleansed repeatedly in a single day, from donning the right attire to disinfecting, which consumes time using traditional ways. Employees perpetually face a hazard of developing an infection under these subjective ways. According to hospital data, even with stricter standards (<xref ref-type="bibr" rid="B6">6</xref>) and more effective cleaning processes, fatal infections are on the rise (<xref ref-type="bibr" rid="B7">7</xref>). These numbers indicate that the existing strategy is insufficient to shield susceptible individuals from serious, perhaps fatal infections like SARS-COV-2 (<xref ref-type="bibr" rid="B8">8</xref>). The Covid 19 pandemic stretched the limits and endurance of healthcare facilities and workers who managed to somehow cope with the challenges. Perhaps the frequent occurrences of epidemics during the present millennium which has seen more than 70 epidemics (<xref ref-type="bibr" rid="B9">9</xref>), played a key role in combatting the covid 19 pandemic. The appeal of using robotic disinfection is gaining traction especially among Hospital administrations, because of automation, economical (decreased labour), increased efficacy (wide spectrum of pathogen), less hazardous residuals and relatively simple procedure in a medical setting (<xref ref-type="bibr" rid="B10">10</xref>). According to a number of studies, disinfection methods that use UVD irradiation are superior to those that do not, lowering microbial load in the environment and possibly lowering risk of contracting a healthcare-associated infection (HAI) (<xref ref-type="bibr" rid="B11">11</xref>&#x2013;<xref ref-type="bibr" rid="B14">14</xref>).</p>
<p>A mobile UV-D robot that can kill microorganisms was created by Guettari et al. (<xref ref-type="bibr" rid="B11">11</xref>). Dancer and King (<xref ref-type="bibr" rid="B12">12</xref>) evaluated the effectiveness of UV light-based automatic decontaminating systems. Critical evaluations on UV disinfection were presented by Abajo et al. (<xref ref-type="bibr" rid="B15">15</xref>) and Raeiszadeh et al. (<xref ref-type="bibr" rid="B16">16</xref>) who also presented a wide array of UV decontamination techniques as well as the effectiveness and security of these UV devices. While Martins et al. (<xref ref-type="bibr" rid="B17">17</xref>) studied the effectiveness of various disinfection techniques for COVID-19 in diverse circumstances, Chiappa et al. (<xref ref-type="bibr" rid="B18">18</xref>) published a narrative review that illustrated the efficacy of a range of UV disinfecting systems against various coronavirus strains. Various studies that discuss applications of UV-D robots (<xref ref-type="bibr" rid="B19">19</xref>&#x2013;<xref ref-type="bibr" rid="B21">21</xref>) to address specific issues encountered during COVID-19 testing, cleaning, and disinfection have also been published.</p>
<p>Nonetheless, the bulk of previously published reviews primarily centered around traditional ultraviolet germicidal irradiation (UVGI) systems, with none addressing the autonomous capabilities of UV-D robots, particularly in the context of medical and dental applications. Although, a new era of robot aid based on artificial intelligence is emerging in dentistry, these robots are still not entirely utilised in dental investigations. Conversely, numerous studies have focused on specific robotic systems within distinct disciplines. For instance, research has delved into the role of robots in tooth preparation within prosthodontics (<xref ref-type="bibr" rid="B22">22</xref>), as well as the utilization of arch-wire bending robots in orthodontics (<xref ref-type="bibr" rid="B23">23</xref>, <xref ref-type="bibr" rid="B24">24</xref>). Furthermore, significant advancements have been made in applying robotic guidance to dental implant placement in oral and maxillofacial surgery (<xref ref-type="bibr" rid="B25">25</xref>&#x2013;<xref ref-type="bibr" rid="B27">27</xref>). The progress in procedures like craniomaxillofacial osteotomy has been notably swift and comprehensive, likely attributed to the rapid development of surgical robotic technologies. In order to thoroughly examine and assess the present situation of practical usage of UV-D robot in dentistry, Yajie Li et al. conducted a scoping assessment of 113 studies in 2021. They came to the conclusion that there are still restrictions and inequalities between robotics research and its use in dentistry (<xref ref-type="bibr" rid="B28">28</xref>). While UV-D robots have been extensively studied and utilized in the realms of prosthodontics, orthodontics, and oral surgery (<xref ref-type="bibr" rid="B22">22</xref>&#x2013;<xref ref-type="bibr" rid="B27">27</xref>), there remains a notable gap in the literature with regard to their comprehensive role in the disinfection process. To the best of our knowledge, numerous research has been published utilizing disinfectant robot in the recent literature (<xref ref-type="bibr" rid="B29">29</xref>&#x2013;<xref ref-type="bibr" rid="B31">31</xref>) and the authors feel that not only it is time to review the findings of these studies but also to review the detailed application of disinfectant robot in dentistry. As a result, the present review sought in determining the current state of robotic dental usage, highlight shortcomings, offer perspectives on their adoption and advancement in the future.</p>
<p>The aim of this review is to emphasize the effective usage of UV-D in dentistry, with specific objectives to comprehensively understand the advancements in technology, design requirements, and applications in healthcare and dental facilities. By accomplishing these objectives, this review seeks to promote further scientific investigations in this emerging and innovative field.</p>
</sec>
<sec id="s2"><label>2.</label><title>Description of the instruments and technology</title>
<sec id="s2a"><label>2.1.</label><title>UV-D robots</title>
<p>Robotics, is defined as the study of reprogrammable, multifaceted, versatile, and extensible systems that dynamically connect sensing to action (<xref ref-type="bibr" rid="B28">28</xref>). UV disinfection robots work on the principle of UVGI using ultraviolet (UV-C) light which has a wavelength of 254&#x2005;nm and provides antimicrobial, antifungal and antiviral properties.</p>
</sec>
<sec id="s2b"><label>2.2.</label><title>UV-D robots in disinfection</title>
<p>UV-D Robots are powered by batteries and can kill up to 99.99&#x0025; of germs. These gadgets are mobile base, have a number of Low-pressure Mercury (LPM) lamp, pulsed xenon lamps, and sensors for motion and are used to supplement hand cleaning (<xref ref-type="bibr" rid="B11">11</xref>, <xref ref-type="bibr" rid="B32">32</xref>). This robot has various functions, including mapping the area, uses passive infrared sensors to sense its environment, camera with three-dimensional imaging to detect obstructions, choice of manual or automatic operation, and an exceptionally high degree of disinfection. They employ the environment&#x2019;s map to provide a high-powered UV dose (<xref ref-type="bibr" rid="B33">33</xref>), and rely on simultaneous localization and mapping (SLAM) (<xref ref-type="bibr" rid="B34">34</xref>), to generate a map of working environment. They can disinfect with UV-C light of 254&#x2005;nm wavelength, and it includes 8&#x2005;UV-C lamps disinfecting a 360&#x00B0; coverage area (<xref ref-type="bibr" rid="B35">35</xref>). A feature of these gadgets is its sensor that keeps track of environmental factors like temperature and humidity. Additionally, sensors that detect movement are employed to instantly shut UV lamps in the event that any humans are found. Traditional UV-D equipment is often either left in one spot in room for the duration of the disinfection cycle or is manually moved by the designated operator to various locations (<xref ref-type="bibr" rid="B5">5</xref>). Various studies have reported that disinfection can benefit from the incorporation of robotics in the management of infectious diseases (<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B36">36</xref>). <xref ref-type="table" rid="T1">Table&#x00A0;1</xref> and <xref ref-type="fig" rid="F1">Figure&#x00A0;1</xref> presents a comparison of UV robots, on the basis of design specifications.</p>
<table-wrap id="T1" position="float"><label>Table 1</label>
<caption><p>Comparison of UV robots based on design specifications.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Features</th>
<th valign="top" align="center">XENEX-Light Strike<break/>[European Institute]</th>
<th valign="top" align="center">TRU-D<break/>[European Institute]</th>
<th valign="top" align="center">HELIOS<break/>[The HELIOS]</th>
<th valign="top" align="center">VIOLET<break/>[Violet, Mc Ginn]</th>
<th valign="top" align="center">AIDBOT<break/>[AIDBOT, Gebhart]</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Founder</td>
<td valign="top" align="left">Mark Tuck Stibich</td>
<td valign="top" align="left">Memphis Tenn</td>
<td valign="top" align="left">Gunner Lyslo</td>
<td valign="top" align="left">Conor McGinn</td>
<td valign="top" align="left">KangGeon Kim</td>
</tr>
<tr>
<td valign="top" align="left">Country origin</td>
<td valign="top" align="left">USA</td>
<td valign="top" align="left">San Diego</td>
<td valign="top" align="left">USA</td>
<td valign="top" align="left">Ireland</td>
<td valign="top" align="left">Korea</td>
</tr>
<tr>
<td valign="top" align="left">Year</td>
<td valign="top" align="left">2014</td>
<td valign="top" align="left">2020</td>
<td valign="top" align="left">2020</td>
<td valign="top" align="left">2020</td>
<td valign="top" align="left">2021</td>
</tr>
<tr>
<td valign="top" align="left">Compactness for use in confined locations</td>
<td valign="top" align="left">Absent</td>
<td valign="top" align="left">Absent</td>
<td valign="top" align="left">Present</td>
<td valign="top" align="left">Present</td>
<td valign="top" align="left">Present</td>
</tr>
<tr>
<td valign="top" align="left">Reduction in majority of microorganisms</td>
<td valign="top" align="left"><italic>Candida auris</italic>, <italic>C. diff</italic>., VRE and CRE</td>
<td valign="top" align="left"><italic>C. diff.</italic>, MRSA, VRE, Ebola and Acinetobacter</td>
<td valign="top" align="left"><italic>C. diff</italic>., MRSA, VRE, Ebola and Acinetobacter</td>
<td valign="top" align="left"><italic>C. diff.</italic>, MRSA, VRE, Ebola and Acinetobacter, SARS-COV-2</td>
<td valign="top" align="left"><italic>C. diff.</italic>, MRSA, VRE, Ebola and Acinetobacter, SARS-COV-2</td>
</tr>
<tr>
<td valign="top" align="left">Autonomous Navigation</td>
<td valign="top" align="left">Absent (uses a separate controller)</td>
<td valign="top" align="left">Absent</td>
<td valign="top" align="left">Present (uses scrub feature)</td>
<td valign="top" align="left">Present</td>
<td valign="top" align="left">Present (uses a mobile controller)</td>
</tr>
<tr>
<td valign="top" align="left">Feasibility of using a cleaning crew and a robot in the same area.</td>
<td valign="top" align="left">Absent</td>
<td valign="top" align="left">Absent</td>
<td valign="top" align="left">Present</td>
<td valign="top" align="left">Present</td>
<td valign="top" align="left">Present</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="table-fn1"><p>USA, United States of America; MRSA, methicillin-resistant <italic>Staphylococcus aureus</italic>; VRE, vancomycin-resistant <italic>Enterococcus</italic>; CRE, carbapenem-resistant <italic>Enterobacteriaceae</italic>; <italic>C. diff.</italic>, <italic>Clostridioides difficile</italic>.</p></fn>
</table-wrap-foot>
</table-wrap>
<fig id="F1" position="float"><label>Figure 1</label>
<caption><p>Examples of different ultraviolet disinfection (UV-D) robots. (<bold>A</bold>) Xenex LightStrike-Germ-Zapping Robot. (<bold>B</bold>) Tru-D Smart UVC robot. (<bold>C</bold>) Helios UV-C Disinfection Robot- Surfacide. (<bold>D</bold>) VIOLET. (<bold>E</bold>) Artificial Intelligence Disinfection ROBOT (AIDBOT).</p></caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="froh-04-1270959-g001.tif"/>
</fig>
</sec>
<sec id="s2c"><label>2.3.</label><title>Service robots in dentistry</title>
<p>Delivering intensive treatments in problematic positions, dentists may feel fatigue ultimately resulting in errors in examining oral cavity and developing subsequent and comprehensive treatment plan. Also, there is the risk of cross-contamination due to negligence or improper handling of apparatus and equipment. Digital medicine and dentistry that are suitable for robot can help to reduce this and improve oral health related quality of life comprehensively (<xref ref-type="bibr" rid="B37">37</xref>). These robots are used in combination with 3D mapping for invasive procedures in dentistry such as tooth preparations, autonomously placing implants, arch wire bending and teeth positioning (<xref ref-type="bibr" rid="B5">5</xref>, <xref ref-type="bibr" rid="B28">28</xref>). Although numerous studies as presented in <xref ref-type="table" rid="T2">Table&#x00A0;2</xref> show the relative application of robots in the field of dentistry but very few studies have discussed the role of UV-D robots in disinfection.</p>
<table-wrap id="T2" position="float"><label>Table 2</label>
<caption><p>Application of robots in the field of dentistry.</p></caption>
<table frame="hsides" rules="groups">
<colgroup>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
<col align="left"/>
</colgroup>
<thead>
<tr>
<th valign="top" align="left">Author/Year</th>
<th valign="top" align="center">ROBOT</th>
<th valign="top" align="center">Application</th>
<th valign="top" align="center">Mechanism</th>
<th valign="top" align="center">Results</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Yeshwante, B et al. (<xref ref-type="bibr" rid="B38">38</xref>)</td>
<td valign="top" align="left">YOMITM (Neocis, Miami, FL, USA)</td>
<td valign="top" align="left">First robotic computer navigation system to receive FDA approval</td>
<td valign="top" align="left">The navigation system uses vibrational feedback</td>
<td valign="top" align="left">Improves clinical precision of implant surgeries and prepares implant osteotomies with excellent predictability and precision.</td>
</tr>
<tr>
<td valign="top" align="left">Woo et al. (<xref ref-type="bibr" rid="B39">39</xref>)</td>
<td valign="top" align="left">6-DOF robotic arm</td>
<td valign="top" align="left">Orthognathic surgery</td>
<td valign="top" align="left">Movement of robotic arm in 6 different directions including translation and rotation</td>
<td valign="top" align="left">Provides high degree of flexibility and agility, making them suitable for tasks requiring accuracy, pace, and consistency.</td>
</tr>
<tr>
<td valign="top" align="left">Ma Q et al. (<xref ref-type="bibr" rid="B40">40</xref>)</td>
<td valign="top" align="left">OMS robot</td>
<td valign="top" align="left">Oral and maxillofacial surgery</td>
<td valign="top" align="left">A self-contained surgical system</td>
<td valign="top" align="left">Assists in surgery providing greater accuracy.</td>
</tr>
<tr>
<td valign="top" align="left">Zhang JT et al. (<xref ref-type="bibr" rid="B41">41</xref>)</td>
<td valign="top" align="left">Robot with novel stapler for stapling</td>
<td valign="top" align="left">Oral and maxillofacial surgery</td>
<td valign="top" align="left">Kinematics control</td>
<td valign="top" align="left">In addition to a novel stapler with one degree of flexibility to close the incision, this robot has six degrees of freedom for location and orientations.</td>
</tr>
<tr>
<td valign="top" align="left">Fang G et al. (<xref ref-type="bibr" rid="B42">42</xref>)</td>
<td valign="top" align="left">MR-safe soft robotic system</td>
<td valign="top" align="left">Head and Neck Cancer</td>
<td valign="top" align="left">MRI-guided</td>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Transoral laser microsurgery</td>
<td valign="top" align="left">Laser-based tumour ablation, high-contrast soft tissue imaging, comprehensive physiological change visualization, and thermometry.</td>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
<td valign="top" align="left"/>
</tr>
<tr>
<td valign="top" align="left">Zhang et al. (<xref ref-type="bibr" rid="B43">43</xref>)</td>
<td valign="top" align="left">6-DOF CRS robot</td>
<td valign="top" align="left">Teeth setting in complete denture (3D)</td>
<td valign="top" align="left">Scanning of the arch</td>
<td valign="top" align="left">Dental arch curve designing based on the patient&#x2019;s jaw arch measurements and view 3D simulated teeth on a screen and adjust each tooth&#x0027;s position with &#x00B1;0.05&#x2005;mm accuracy.</td>
</tr>
<tr>
<td valign="top" align="left">Jiang, J et al. (<xref ref-type="bibr" rid="B44">44</xref>)</td>
<td valign="top" align="left">Robotic system for tooth arrangement (50 D- DOF)</td>
<td valign="top" align="left">Teeth-arrangement</td>
<td valign="top" align="left">Robotic arm in 6 different directions</td>
<td valign="top" align="left">Manufacturing of the full denture is finished in about 30&#x2005;min with &#x00B1;0.07&#x2005;mm accuracy.</td>
</tr>
<tr>
<td valign="top" align="left">Alford T.J et al. (<xref ref-type="bibr" rid="B45">45</xref>)</td>
<td valign="top" align="left">SureSmile OAW bending robot</td>
<td valign="top" align="left">Orthodontics</td>
<td valign="top" align="left">Power function model.</td>
<td valign="top" align="left">Diagnose patients, simulating treatment plans, and personalize fixed orthodontic equipment.</td>
</tr>
<tr>
<td valign="top" align="left">Burdea et al. (<xref ref-type="bibr" rid="B46">46</xref>)</td>
<td valign="top" align="left">WidowX 250 Robot Arm 6DOF</td>
<td valign="top" align="left">Oral Medicine and Radiology</td>
<td valign="top" align="left">6-DOF robot arm, x-ray source and film</td>
<td valign="top" align="left">Dental subtraction radiography</td>
</tr>
<tr>
<td valign="top" align="left">Wu Y et al. (<xref ref-type="bibr" rid="B47">47</xref>)</td>
<td valign="top" align="left">Remebot Dental Robot</td>
<td valign="top" align="left">Prosthodontics and Oral Surgery</td>
<td valign="top" align="left">3D printing</td>
<td valign="top" align="left">Performs two distal zygomatic implants on maxilla and two immediately loaded full-arch fixed implant rehabilitation on the mandible.</td>
</tr>
<tr>
<td valign="top" align="left">Hwang G et al. in 2019 (<xref ref-type="bibr" rid="B48">48</xref>)</td>
<td valign="top" align="left">Catalytic antimicrobial robots (CARs)</td>
<td valign="top" align="left">Others</td>
<td valign="top" align="left">Dual catalytic-magnetic functionality using magnetic field powered robotic assemblies.</td>
<td valign="top" align="left">Create bactericidal free radicals and fighting persistent biofilm infections</td>
</tr>
<tr>
<td valign="top" align="left">P. Vela-Anton (<xref ref-type="bibr" rid="B49">49</xref>)</td>
<td valign="top" align="left">Borjibot</td>
<td valign="top" align="left">Pedodontics</td>
<td valign="top" align="left">Torsional movement</td>
<td valign="top" align="left">A sensitive automation system for newborn oral cognitive training that provides force and torsional stimuli</td>
</tr>
<tr>
<td valign="top" align="left">Kasimoglu Yv et al. (<xref ref-type="bibr" rid="B50">50</xref>)</td>
<td valign="top" align="left">Humanoid robots</td>
<td valign="top" align="left">Pedodontics</td>
<td valign="top" align="left">Techno-psychological distraction technique using multimodal assessment</td>
<td valign="top" align="left">A robot with humanoids to help Adolescents with dental fear of the dentist in children</td>
</tr>
<tr>
<td valign="top" align="left">Sakaeda et al. (<xref ref-type="bibr" rid="B51">51</xref>)</td>
<td valign="top" align="left">Shapeshifting microrobots</td>
<td valign="top" align="left">Public Health Dentistry</td>
<td valign="top" align="left">Human-centred design technology and system integration technology</td>
<td valign="top" align="left">An automatic teeth cleaning robot that replicated 3D brushing motions over time</td>
</tr>
<tr>
<td valign="top" align="left">Zhao R et al. (<xref ref-type="bibr" rid="B52">52</xref>)</td>
<td valign="top" align="left">Integrated dental robot system</td>
<td valign="top" align="left">Oral Medicine and Radiology</td>
<td valign="top" align="left">Robot technology</td>
<td valign="top" align="left">Diagnosis and maintenance care</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="table-fn2"><p>FDA, Food and Drug Administration; MRI, magnetic resonance imaging; 3D, three dimensional; D, degree; DOF, degree of freedom.</p></fn>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="s2d"><label>2.4.</label><title>Will UV-D disinfection robots complement in the field of dentistry?</title>
<p>Robotic dentistry has revolutionized the practice of dentistry, transforming both the mindset and approach of healthcare providers while simultaneously elevating the quality of patient care. This technological advancement has ushered in a standardized approach to harnessing robotic capabilities across various dental tasks. In the medical field, numerous studies have showcased the advantages of employing UV-D technology for disinfection purposes, extending to applications like tooth preparations and dental implant placement in prosthodontics (<xref ref-type="bibr" rid="B22">22</xref>), arch-wire bending robots in orthodontics, and robot-assisted craniomaxillofacial osteotomy in oral and maxillofacial surgery (<xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B26">26</xref>). Surprisingly, despite these advancements, there have been no studies that explore the potential of UV-D robots for disinfecting dental operatories.</p>
<p>Despite the fact that they were developed for certain tasks such multisensory transportation and altering cells, their uses for chemical and physical biofilm destruction are still being researched (<xref ref-type="bibr" rid="B53">53</xref>). Hwang and colleagues (<xref ref-type="bibr" rid="B48">48</xref>) created catalytic antimicrobial robots (CARs) that could degrade and eliminate biofilms on surfaces in a controlled, effective, and precise manner. These &#x201C;kill-grade-and-remove&#x201D; CAR systems could be applied in dentistry to treat persistent biofilm infections. Thus, considering all of these changes, it becomes imperative to use a UV-D robot that is designed specifically to perform disinfection in dentistry. A new technology must overcome a number of challenges like acceptability, awareness and compliance when it is brought into a new environment. The high cost of technical breakthroughs in medical and dental applications is one such barrier. Additionally, robotic systems are sophisticated and need specialized knowledge to perform well (<xref ref-type="bibr" rid="B54">54</xref>). Therefore, the effectiveness of the outcomes would depend on how well the staff feed the data into the robotic system.</p>
</sec>
</sec>
<sec id="s3" sec-type="discussion"><label>3.</label><title>Discussion</title>
<sec id="s3a"><label>3.1.</label><title>Demonstrated success of UV-D robots in dentistry</title>
<p>A variety of diseases can be encountered in polluted hospital environments. Contaminated surfaces provide a risk that cannot be eradicated with the help of traditional manual methods for disinfection and cleaning (<xref ref-type="bibr" rid="B55">55</xref>). Furthermore, traditional disinfectants were unavailable during the COVID-19 epidemic, necessitating the use of innovative disinfectants or disinfection procedures. To solve these shortcomings, UVC disinfection machines that move autonomously, or UVC robots, have been developed (<xref ref-type="bibr" rid="B56">56</xref>). Dentistry is evolving into a new era of the robot-assistance based on artificial intelligence. However, these robots are still not fully incorporated into studies on dentistry. A first prototype for remote robotic dentistry was developed over the course of the past year by a group of senior biomedical engineering students at South Dakota Mines, of STEM university in South Dakota, in 2023 in collaboration with a dentist. They stated that UV-D robots could aid in improving underprivileged communities access to attain dental treatment. They also pointed out that contemporary dentistry already uses intricate and meticulous 3D scans of the oral cavity, allowing a surgery like a filling to be planned out digitally well in advance of any procedure (<xref ref-type="bibr" rid="B57">57</xref>). Another recently conducted research by Linn et al. in 2023 at Taipei Medical University, Taiwan employed three distinct implant sizes with 76 drilling sites in partly edentulous models, comparing the effectiveness of robotic and human unaided drilling. Algorithms for standardization and incrementally drilling techniques was used for the robotic procedure. Following the drilling process, differences between the implant&#x2019;s actual position and the intended position were identified and it was further concluded that the best precision and dependability for the preoperative plan for small implant diameters can be provided by a robotic surgical system (<xref ref-type="bibr" rid="B58">58</xref>). A revolutionary method of interactive operative assistance, robot-assisted dental implant placement provides directions in placing implants, osteotomy preparation, and implant insertion in addition to visual navigation.</p>
<p>Van Riet TCT et al. in 2021 conducted a systematic review and provided a complete, transparent, and evidence-based assessment of study characteristics with state of progress of robotic initiatives in dentistry (<xref ref-type="bibr" rid="B59">59</xref>). Adel S et al. in 2021, conducted a scoping review and further 87 studies were added to the systematic review and stated that there has been significant research in the previous ten years on surgical robots for diagnosis, and arch wire bending. Nanorobots and rehabilitative robots hold great promise and have received a lot of attention in the orthodontic literature (<xref ref-type="bibr" rid="B60">60</xref>). Thus, numerous studies have been published utilizing its applications in dentistry, such as orthodontics, Prosthodontics and oral surgery, but there are very few studies suggesting its use in disinfection (<xref ref-type="bibr" rid="B59">59</xref>&#x2013;<xref ref-type="bibr" rid="B62">62</xref>).</p>
<p>Boston Dental Clinic, a prominent dental practice in Boston, Massachusetts, and few clinics in Dubai, UAE, disinfects clinics with UV-D robots. This self-cleaning technology eliminates harmful microbes by disinfecting a 360-degree area with eight UV-C ultraviolet lasers, removing 99.99&#x0025; of all viruses and bacteria. They also demonstrated that these UV-D robots are more effective than manual cleaning methods such as disinfectant spray and slow spread of COVID-19 thereby protecting frontline healthcare professionals. To protect individuals around them, the robots have a panic button and sensor-based security features that turn off UV lamps whenever a human is in close proximity to robots that are sanitizing (<xref ref-type="bibr" rid="B63">63</xref>). Cimolai (<xref ref-type="bibr" rid="B64">64</xref>) offers a comprehensive examination of COVID-19&#x2019;s environmental implications and cleaning methods. In light of this, future investigations should focus on real-world assessments to detect contagious viruses. Achieving this can be simplified with UV-D robotic processors (<xref ref-type="bibr" rid="B14">14</xref>). These automated UV-D robots are equipped with graphical processors for object recognition and visual analysis, enhancing space sterilization efficiency. UV-D robots excel in identifying potentially contaminated objects, such as control surfaces and doorknobs, through extended exposure to UV-C light, ensuring thorough disinfection of these items.</p>
<p>The UVD robot&#x2019;s irradiation time and speed should be adjusted to disinfect objects which are highly infested with pathogenic organisms in accordance with the results of object detection (<xref ref-type="bibr" rid="B65">65</xref>). Even though UV-C dosage for 99.9&#x0025; COVID-19 disinfection has not been explicitly stated, it is known that under controlled laboratory circumstances, 100&#x2013;200&#x2005;J/m<sup>2</sup> is the UV-C dose required to inactivate 99.9&#x0025; of related SARS family viruses (<xref ref-type="bibr" rid="B66">66</xref>). First, due to the UV-C light&#x2019;s (254&#x2005;nm) harmful effects on nearby humans as well as possibility of bacteria regeneration or freshly contaminants at locations after sterilization, the robot&#x2019;s operational duration should be monitored closely. UV-C (222&#x2005;nm), a recently used wavelength for disinfection, has a lesser sterilizing efficacy but a less hazardous effect; it can be used only at certain periods when there are humans nearby (<xref ref-type="bibr" rid="B67">67</xref>).</p>
<p>The use of UV robots for disinfection raises a variety of unaddressed research problems, including better operator plans, organizing paths for maximizing UV irradiation, creating effective disinfecting procedures, and technologies to reduce UV radiation potential hazards. Thus, future hospitals&#x2019; design and inventory must provide for electronic communication between various work and patient-care systems, including those involving cleaning and disinfection robots in dental hospitals.</p>
</sec>
</sec>
<sec id="s4" sec-type="conclusions"><label>4.</label><title>Conclusions</title>
<p>The decontamination procedure in healthcare facilities using UV-D robots is fascinating. These robots hold immense potential for future innovations, impacting sociological, public, and healthcare aspects. However, some challenges need addressing, such as improving hospital and device design for better robot visibility and movement. Additionally, customized approaches are required to determine the ideal wavelength and irradiation period for effectively inactivating specific pathogens on different surfaces. To fully integrate this innovative technology, further technical developments and clinical studies across various hospitals are essential. By leveraging the convergence of robotics and dentistry, UV-D disinfection in dental hospitals shows promising benefits and opens up a wide range of opportunities.</p>
</sec>
</body>
<back>
<sec id="s5" sec-type="author-contributions"><title>Author contributions</title>
<p>VP: Conceptualization, Methodology, Project administration, Writing &#x2013; review and editing. MM: Methodology, Writing &#x2013; review and editing. AH: Writing &#x2013; original draft. HA: Writing &#x2013; original draft. AS: Formal Analysis, Writing &#x2013; review and editing. KM: Methodology, Writing &#x2013; review and editing. VM: Conceptualization, Methodology, Project administration, Writing &#x2013; review and editing. AM: Methodology, Writing &#x2013; review and editing. AM: Formal Analysis, Writing &#x2013; review and editing.</p>
</sec>
<sec id="s11" sec-type="funding-information"><title>Funding</title>
<p>The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.</p>
</sec>
<sec id="s6" sec-type="COI-statement"><title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="s7" sec-type="disclaimer"><title>Publisher&#x0027;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<ref-list><title>References</title>
<ref id="B1"><label>1.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Li</surname><given-names>Y</given-names></name><name><surname>Hu</surname><given-names>J</given-names></name><name><surname>Tao</surname><given-names>B</given-names></name><name><surname>Yu</surname><given-names>D</given-names></name><name><surname>Shen</surname><given-names>Y</given-names></name><name><surname>Fan</surname><given-names>S</given-names></name><etal/></person-group> <article-title>Automatic robot-world calibration in an optical-navigated surgical robot system and its application for oral implant placement</article-title>. <source>Int J CARS</source>. (<year>2020</year>) <volume>15</volume>:<fpage>1685</fpage>&#x2013;<lpage>92</lpage>. <pub-id pub-id-type="doi">10.1007/s11548-020-02232-w</pub-id></citation></ref>
<ref id="B2"><label>2.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Saheb</surname><given-names>T</given-names></name><name><surname>Izadi</surname><given-names>L</given-names></name></person-group>. <article-title>Paradigm of IoT big data analytics in the healthcare industry: a review of scientific literature and mapping of research trends</article-title>. <source>Telemat Inform</source>. (<year>2019</year>) <volume>41</volume>:<fpage>70</fpage>&#x2013;<lpage>85</lpage>. <pub-id pub-id-type="doi">10.1016/j.tele.2019.03.005</pub-id></citation></ref>
<ref id="B3"><label>3.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kitagawa</surname><given-names>H</given-names></name><name><surname>Nomura</surname><given-names>T</given-names></name><name><surname>Nazmul</surname><given-names>T</given-names></name><name><surname>Omori</surname><given-names>K</given-names></name><name><surname>Shigemoto</surname><given-names>N</given-names></name><name><surname>Sakaguchi</surname><given-names>T</given-names></name><etal/></person-group> <article-title>Effectiveness of 222-nm ultraviolet light on disinfecting SARS-CoV-2 surface contamination</article-title>. <source>Am J Infect Control</source>. (<year>2021</year>) <volume>49</volume>:<fpage>299</fpage>&#x2013;<lpage>301</lpage>. <pub-id pub-id-type="doi">10.1016/j.ajic.2020.08.022</pub-id><pub-id pub-id-type="pmid">32896604</pub-id></citation></ref>
<ref id="B4"><label>4.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Riddell</surname><given-names>S</given-names></name><name><surname>Goldie</surname><given-names>S</given-names></name><name><surname>Hill</surname><given-names>A</given-names></name><name><surname>Eagles</surname><given-names>D</given-names></name><name><surname>Drew</surname><given-names>TW</given-names></name></person-group>. <article-title>The effect of temperature on persistence of SARS-CoV-2 on common surfaces</article-title>. <source>Virol J</source>. (<year>2020</year>) <volume>17</volume>:<fpage>145</fpage>. <pub-id pub-id-type="doi">10.1186/s12985-020-01418-7</pub-id><pub-id pub-id-type="pmid">33028356</pub-id></citation></ref>
<ref id="B5"><label>5.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mehta</surname><given-names>I</given-names></name><name><surname>Hsueh</surname><given-names>H-Y</given-names></name><name><surname>Taghipour</surname><given-names>S</given-names></name><name><surname>Li</surname><given-names>W</given-names></name><name><surname>Saeedi</surname><given-names>S</given-names></name></person-group>. <article-title>UV disinfection robots: a review</article-title>. <source>Rob Auton Syst</source>. (<year>2023</year>) <volume>161</volume>:<fpage>104332</fpage>. <pub-id pub-id-type="doi">10.1016/j.robot.2022.104332</pub-id><pub-id pub-id-type="pmid">36514383</pub-id></citation></ref>
<ref id="B6"><label>6.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Ontario</surname><given-names>HQ</given-names></name></person-group>. <article-title>Portable ultraviolet light surface-disinfecting devices for prevention of hospital-acquired infections: a health technology assessment</article-title>. <source>Ontario Health Technol. Assess. Ser</source>. (<year>2018</year>) <volume>18</volume>(<issue>1</issue>):<fpage>1</fpage>. <pub-id pub-id-type="pmid">29487629</pub-id>.</citation></ref>
<ref id="B7"><label>7.</label><citation citation-type="other"><person-group person-group-type="author"><name><surname>Fong</surname><given-names>A</given-names></name></person-group>. <comment><italic>Characterization of the novel 4-chloro-1-piperidin-1ylmethyl-1H-indole-2, 3-dione compound (Raja 42) for its antibacterial activity against Escherichia coli, Clostridium difficile, Staphylococcus aureus and Helicobacter pylori (Doctoral dissertation, Laurentian University of Sudbury)</italic></comment>. <comment>Available at:</comment> <ext-link ext-link-type="uri" xlink:href="https://zone.biblio.laurentian.ca/handle/10219/3641">https://zone.biblio.laurentian.ca/handle/10219/3641</ext-link></citation></ref>
<ref id="B8"><label>8.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Yang</surname><given-names>G-Z</given-names></name><name><surname>Nelson B</surname><given-names>J</given-names></name><name><surname>Murphy</surname><given-names>RR</given-names></name><name><surname>Choset</surname><given-names>H</given-names></name><name><surname>Christensen</surname><given-names>H</given-names></name><name><surname>Collins S</surname><given-names>H</given-names></name><etal/></person-group> <article-title>Combating COVID-19&#x2014;the role of robotics in managing public health and infectious diseases</article-title>. <source>Sci Robot</source>. (<year>2020</year>) <volume>5</volume>:<fpage>eabb5589</fpage>. <pub-id pub-id-type="doi">10.1126/scirobotics.abb5589</pub-id><pub-id pub-id-type="pmid">33022599</pub-id></citation></ref>
<ref id="B9"><label>9.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mattoo</surname><given-names>KA</given-names></name><name><surname>Jain</surname><given-names>S</given-names></name></person-group>. <article-title>Managing prosthodontic (geriatric) patients during the SARS-CoV-2 pandemic</article-title>. <source>J Int Oral Health</source>. (<year>2020</year>) <volume>12</volume>(<issue>8</issue>):<fpage>69</fpage>. <pub-id pub-id-type="doi">10.4103/jioh.jioh_233_20</pub-id></citation></ref>
<ref id="B10"><label>10.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Casini</surname><given-names>B</given-names></name><name><surname>Tuvo</surname><given-names>B</given-names></name><name><surname>Cristina</surname><given-names>ML</given-names></name><name><surname>Spagnolo</surname><given-names>AM</given-names></name><name><surname>Totaro</surname><given-names>M</given-names></name><name><surname>Baggiani</surname><given-names>A</given-names></name><etal/></person-group> <article-title>Evaluation of an ultraviolet C (UVC) light-emitting device for doi: 10.3390/ijerph16193572 disinfection of high touch surfaces in hospital critical areas</article-title>. <source>IJERPH</source>. (<year>2019</year>) <volume>16</volume>:<fpage>3572</fpage>. <pub-id pub-id-type="doi">10.3390/ijerph16193572</pub-id><pub-id pub-id-type="pmid">31554297</pub-id></citation></ref>
<ref id="B11"><label>11.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Guettari</surname><given-names>M</given-names></name><name><surname>Gharbi</surname><given-names>I</given-names></name><name><surname>Hamza</surname><given-names>S</given-names></name></person-group>. <article-title>UVC disinfection robot</article-title>. <source>Environ Sci Pollut Res</source>. (<year>2021</year>) <volume>28</volume>:<fpage>40394</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1007/s11356-020-11184-2</pub-id></citation></ref>
<ref id="B12"><label>12.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Dancer</surname><given-names>SJ</given-names></name><name><surname>King</surname><given-names>M-F</given-names></name></person-group>. <article-title>Systematic review on use, cost and clinical efficacy of automated decontamination devices</article-title>. <source>Antimicrob Resist Infect Control</source>. (<year>2021</year>) <volume>10</volume>:<fpage>34</fpage>. <pub-id pub-id-type="doi">10.1186/s13756-021-00894-y</pub-id><pub-id pub-id-type="pmid">33579386</pub-id></citation></ref>
<ref id="B13"><label>13.</label><citation citation-type="confproc"><conf-name>Perminov, mikhailovskiy, sedunin, okunevich, kalinov, kurenkov, tsetserukou, UltraBot: autonomous mobile robot for indoor UV-C disinfection, in: international conference on automation science and engineering, CASE</conf-name>, (<year>2021</year>).</citation></ref>
<ref id="B14"><label>14.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fuchs</surname><given-names>FM</given-names></name><name><surname>Bibinov</surname><given-names>N</given-names></name><name><surname>Blanco</surname><given-names>EV</given-names></name><name><surname>Pfaender</surname><given-names>S</given-names></name><name><surname>Thei&#x00DF;</surname><given-names>S</given-names></name><name><surname>Wolter</surname><given-names>H</given-names></name><etal/></person-group> <article-title>Characterization of a robot-assisted UV-C disinfection for the inactivation of surface-associated microorganisms and viruses</article-title>. <source>J Photochem Photobiol</source>. (<year>2022</year>) <volume>11</volume>:<fpage>100123</fpage>. <pub-id pub-id-type="doi">10.1016/j.jpap.2022.100123</pub-id><pub-id pub-id-type="pmid">36034107</pub-id></citation></ref>
<ref id="B15"><label>15.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>de Abajo FJ</surname><given-names>G</given-names></name><name><surname>Hern&#x00E1;ndez</surname><given-names>RJ</given-names></name><name><surname>Kaminer</surname><given-names>I</given-names></name><name><surname>Meyerhans</surname><given-names>A</given-names></name><name><surname>Rosell-Llompart</surname><given-names>J</given-names></name><name><surname>Sanchez-Elsner</surname><given-names>T</given-names></name></person-group>. <article-title>Back to normal: an old physics route to reduce SARS-CoV-2 transmission in indoor spaces</article-title>. <source>ACS Nano</source>. (<year>2020</year>) <volume>14</volume>:<fpage>7704</fpage>&#x2013;<lpage>13</lpage>. <pub-id pub-id-type="doi">10.1021/acsnano.0c04596</pub-id><pub-id pub-id-type="pmid">32551537</pub-id></citation></ref>
<ref id="B16"><label>16.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Raeiszadeh</surname><given-names>M</given-names></name><name><surname>Adeli</surname><given-names>B</given-names></name></person-group>. <article-title>A critical review on ultraviolet disinfection systems against COVID-19 outbreak: applicability, validation, and safety considerations</article-title>. <source>ACS Photonics</source>. (<year>2020</year>) <volume>7</volume>:<fpage>2941</fpage>&#x2013;<lpage>51</lpage>. <pub-id pub-id-type="doi">10.1021/acsphotonics.0c01245</pub-id><pub-id pub-id-type="pmid">37556269</pub-id></citation></ref>
<ref id="B17"><label>17.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Martins CP</surname><given-names>V</given-names></name><name><surname>Xavier</surname><given-names>CSF</given-names></name><name><surname>Cobrado</surname><given-names>L</given-names></name></person-group>. <article-title>Disinfection methods against SARS-CoV-2: a systematic review</article-title>. <source>J Hosp Infect</source>. (<year>2022</year>) <volume>119</volume>:<fpage>84</fpage>&#x2013;<lpage>117</lpage>. <pub-id pub-id-type="doi">10.1016/j.jhin.2021.07.014</pub-id><pub-id pub-id-type="pmid">34673114</pub-id></citation></ref>
<ref id="B18"><label>18.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Chiappa</surname><given-names>F</given-names></name><name><surname>Frascella</surname><given-names>B</given-names></name><name><surname>Vigezzi</surname><given-names>GP</given-names></name><name><surname>Moro</surname><given-names>M</given-names></name><name><surname>Diamanti</surname><given-names>L</given-names></name><name><surname>Gentile</surname><given-names>L</given-names></name><etal/></person-group> <article-title>The efficacy of ultraviolet light-emitting technology against coronaviruses: a systematic review</article-title>. <source>J Hosp Infect</source>. (<year>2021</year>) <volume>114</volume>:<fpage>63</fpage>&#x2013;<lpage>78</lpage>. <pub-id pub-id-type="doi">10.1016/j.jhin.2021.05.005</pub-id><pub-id pub-id-type="pmid">34029626</pub-id></citation></ref>
<ref id="B19"><label>19.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Barfoot</surname><given-names>T</given-names></name><name><surname>Burgner-Kahrs</surname><given-names>J</given-names></name><name><surname>Diller</surname><given-names>E</given-names></name><name><surname>Garg</surname><given-names>A</given-names></name><name><surname>Goldenberg</surname><given-names>A</given-names></name><name><surname>Kelly</surname><given-names>J</given-names></name><etal/></person-group> <source>Making sense of the robotized pandemic response: a comparison of global and Canadian robot deployments and success factors</source>. <publisher-name>University of Toronto Robotics Institute</publisher-name> (<year>2020</year>). <ext-link ext-link-type="uri" xlink:href="https://arxiv.org/abs/2009.08577">https://arxiv.org/abs/2009.08577</ext-link></citation></ref>
<ref id="B20"><label>20.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Di Lallo</surname><given-names>A</given-names></name><name><surname>Murphy</surname><given-names>RR</given-names></name><name><surname>Krieger</surname><given-names>A</given-names></name><name><surname>Zhu</surname><given-names>J</given-names></name><name><surname>Taylor</surname><given-names>RH</given-names></name><name><surname>Su</surname><given-names>H</given-names></name></person-group>. <article-title>Medical robots for infectious diseases: lessons and challenges from the COVID-19 pandemic</article-title>. <source>arXiv <italic>preprint</italic></source> (<year>2020</year>):<comment>arXiv:2012.07756</comment>. <pub-id pub-id-type="doi">10.1109/MRA.2020.3045671</pub-id></citation></ref>
<ref id="B21"><label>21.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gao</surname><given-names>A</given-names></name><name><surname>Murphy</surname><given-names>RR</given-names></name><name><surname>Chen</surname><given-names>W</given-names></name><name><surname>Dagnino</surname><given-names>G</given-names></name><name><surname>Fischer</surname><given-names>P</given-names></name><name><surname>Gutierrez</surname><given-names>MG</given-names></name><etal/></person-group> <article-title>Progress in robotics for combating infectious diseases</article-title>. <source>Sci Robot</source>. (<year>2021</year>) <volume>6</volume>:<fpage>eabf1462</fpage>. <pub-id pub-id-type="doi">10.1126/scirobotics.abf1462</pub-id><pub-id pub-id-type="pmid">34043552</pub-id></citation></ref>
<ref id="B22"><label>22.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Yuan</surname><given-names>F</given-names></name><name><surname>Lyu</surname><given-names>P</given-names></name></person-group>. <article-title>A preliminary study on a tooth preparation robot</article-title>. <source>Adv Appl Ceram</source>. (<year>2020</year>) <volume>119</volume>:<fpage>332</fpage>&#x2013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1080/17436753.2019.1666555</pub-id></citation></ref>
<ref id="B23"><label>23.</label><citation citation-type="confproc"><person-group person-group-type="author"><name><surname>Zhang</surname><given-names>Y</given-names></name><name><surname>Jia</surname><given-names>Y</given-names></name></person-group>. <conf-name>The control of archwire bending robot based on MOTOMAN UP6</conf-name>. <conf-name>In proceedings of the 2009 2nd international conference on biomedical engineering and informatics</conf-name>; <conf-date>October 17&#x2013;19 2009</conf-date>; <conf-loc>Tianjin, China</conf-loc> <fpage>1</fpage>&#x2013;<lpage>5</lpage>.</citation></ref>
<ref id="B24"><label>24.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Du</surname><given-names>H</given-names></name><name><surname>Jia</surname><given-names>Y</given-names></name><name><surname>Zhang</surname><given-names>Y</given-names></name><name><surname>Liu</surname><given-names>Y</given-names></name></person-group>. <article-title>Trajectory planning of archwire bending robot</article-title>. <source>China Mech. Eng</source>. (<year>2010</year>) <volume>21</volume>:<fpage>1605</fpage>&#x2013;<lpage>8</lpage>.</citation></ref>
<ref id="B25"><label>25.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bolding</surname><given-names>SL</given-names></name><name><surname>Reebye</surname><given-names>UN</given-names></name></person-group>. <article-title>Accuracy of haptic robotic guidance of dental implant surgery for completely edentulous arches</article-title>. <source>J Prosthet Dent</source>. (<year>2022</year>) <volume>128</volume>:<fpage>639</fpage>&#x2013;<lpage>47</lpage>. <pub-id pub-id-type="doi">10.1016/j.prosdent.2020.12.048</pub-id><pub-id pub-id-type="pmid">33678441</pub-id></citation></ref>
<ref id="B26"><label>26.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wu</surname><given-names>J</given-names></name><name><surname>Hui</surname><given-names>W</given-names></name><name><surname>Niu</surname><given-names>J</given-names></name><name><surname>Chen</surname><given-names>S</given-names></name><name><surname>Lin</surname><given-names>Y</given-names></name><name><surname>Luan</surname><given-names>N</given-names></name><etal/></person-group> <article-title>Collaborative control method and experimental research on robot-assisted craniomaxillofacial osteotomy based on the force feedback and optical navigation</article-title>. <source>J Craniofac Surg</source>. (<year>2022</year>) <volume>33</volume>:<fpage>2011</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1097/SCS.0000000000008684</pub-id><pub-id pub-id-type="pmid">35864585</pub-id></citation></ref>
<ref id="B27"><label>27.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cao</surname><given-names>Z</given-names></name><name><surname>Qin</surname><given-names>C</given-names></name><name><surname>Fan</surname><given-names>S</given-names></name><name><surname>Yu</surname><given-names>D</given-names></name><name><surname>Wu</surname><given-names>Y</given-names></name><name><surname>Qin</surname><given-names>J</given-names></name><etal/></person-group> <article-title>Pilot study of a surgical robot system for zygomatic implant placement</article-title>. <source>Med Eng Phys</source>. (<year>2020</year>) <volume>75</volume>:<fpage>72</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1016/j.medengphy.2019.07.020</pub-id><pub-id pub-id-type="pmid">31677890</pub-id></citation></ref>
<ref id="B28"><label>28.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Li</surname><given-names>Y</given-names></name><name><surname>Inamochi</surname><given-names>Y</given-names></name><name><surname>Wang</surname><given-names>Z</given-names></name><name><surname>Fueki</surname><given-names>K</given-names></name></person-group>. <article-title>Clinical application of robots in dentistry: a scoping review</article-title>. <source>J Prosthodont Res</source>. (<year>2023</year>). <pub-id pub-id-type="doi">10.2186/jpr.JPR_D_23_00027</pub-id></citation></ref>
<ref id="B29"><label>29.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Liu</surname><given-names>HC</given-names></name></person-group>. <article-title>Artificial intelligence stomatology</article-title>. <source>Zhonghua Kou Qiang Yi Xue Za Zhi</source>. (<year>2020</year>) <volume>55</volume>:<fpage>915</fpage>&#x2013;<lpage>9</lpage>. <comment>(in Chinese)</comment>. <pub-id pub-id-type="doi">10.1146/annurevbioeng-060418-052502</pub-id><pub-id pub-id-type="pmid">33280353</pub-id></citation></ref>
<ref id="B30"><label>30.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Grischke</surname><given-names>J</given-names></name><name><surname>Johannsmeier</surname><given-names>L</given-names></name><name><surname>Eich</surname><given-names>L</given-names></name><name><surname>Griga</surname><given-names>L</given-names></name><name><surname>Haddadin</surname><given-names>S</given-names></name></person-group>. <article-title>Dentronics: towards robotics and artificial intelligence in dentistry</article-title>. <source>Dent Mater</source>. (<year>2020</year>) <volume>36</volume>:<fpage>765</fpage>&#x2013;<lpage>78</lpage>. <pub-id pub-id-type="doi">10.1016/j.dental.2020.03.021</pub-id><pub-id pub-id-type="pmid">32349877</pub-id></citation></ref>
<ref id="B31"><label>31.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Ivashchenko</surname><given-names>AV</given-names></name><name><surname>Yablokov</surname><given-names>AE</given-names></name><name><surname>Komlev</surname><given-names>SS</given-names></name><name><surname>Stepanov</surname><given-names>GV</given-names></name><name><surname>Tsimbalistov</surname><given-names>AV</given-names></name></person-group>. <article-title>Robot-assisted and robotic systems used in dentistry</article-title>. <source>Stomat</source>. (<year>2020</year>) <volume>99</volume>:<fpage>95</fpage>. <pub-id pub-id-type="doi">10.17116/stomat20209901195</pub-id></citation></ref>
<ref id="B32"><label>32.</label><citation citation-type="book"><person-group person-group-type="author"><name><surname>Begi&#x0107;</surname><given-names>A</given-names></name></person-group>. <article-title>Application of service robots for disinfection in medical institutions</article-title>. In: <person-group person-group-type="editor"><name><surname>Had&#x017E;ikadi&#x0107;</surname><given-names>M</given-names></name><name><surname>Avdakovi&#x0107;</surname><given-names>S</given-names></name></person-group>, editors. <source>Advanced technologies, systems, and applications II</source>. <publisher-loc>Cham</publisher-loc>: <publisher-name>Springer International Publishing</publisher-name> (<year>2018</year>). p. <fpage>1056</fpage>&#x2013;<lpage>65</lpage>.</citation></ref>
<ref id="B33"><label>33.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Ackerman</surname><given-names>E</given-names></name></person-group>. <article-title>Autonomous robots are helping kill coronavirus in hospitals</article-title>. <source>IEEE Spectr</source>. (<year>2020</year>) <volume>11</volume>. (<comment>Accessed July 01, 2023</comment>).</citation></ref>
<ref id="B34"><label>34.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Saeedi</surname><given-names>S</given-names></name><name><surname>Spink</surname><given-names>T</given-names></name><name><surname>Gorgovan</surname><given-names>C</given-names></name><name><surname>Webb</surname><given-names>A</given-names></name><name><surname>Clarkson</surname><given-names>J</given-names></name><name><surname>Tomusk</surname><given-names>E</given-names></name><etal/></person-group> <article-title>Navigating the landscape for real-time localization and mapping for robotics and virtual and augmented reality</article-title>. <source>Proc IEEE</source>. (<year>2018</year>) <volume>106</volume>:<fpage>2020</fpage>&#x2013;<lpage>39</lpage>. <pub-id pub-id-type="doi">10.1109/JPROC.2018.2856739</pub-id></citation></ref>
<ref id="B35"><label>35.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Suleyman</surname><given-names>G</given-names></name><name><surname>Alangaden</surname><given-names>G</given-names></name><name><surname>Bardossy</surname><given-names>AC</given-names></name></person-group>. <article-title>The role of environmental contamination in the transmission of nosocomial pathogens and healthcare-associated infections</article-title>. <source>Curr Infect Dis Rep</source>. (<year>2018</year>) <volume>20</volume>:<fpage>12</fpage>. <pub-id pub-id-type="doi">10.1007/s11908-018-0620-2</pub-id><pub-id pub-id-type="pmid">29704133</pub-id></citation></ref>
<ref id="B36"><label>36.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Zaman</surname><given-names>A</given-names></name><name><surname>Shahjahan Majib</surname><given-names>M</given-names></name><name><surname>Tanjim</surname><given-names>SA</given-names></name><name><surname>Siddique</surname><given-names>S</given-names></name><name><surname>Islam</surname><given-names>S</given-names></name><name><surname>Aadeeb</surname><given-names>MS</given-names></name><etal/></person-group> <article-title>UVC-PURGE: a novel cost-effective disinfection robot for combating COVID-19 pandemic</article-title>. <source>IEEE Access</source>. (<year>2022</year>) <volume>10</volume>:<fpage>37613</fpage>&#x2013;<lpage>34</lpage>. <pub-id pub-id-type="doi">10.1109/ACCESS.2022.3163243</pub-id><pub-id pub-id-type="pmid">35582495</pub-id></citation></ref>
<ref id="B37"><label>37.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Ahmad</surname><given-names>P</given-names></name><name><surname>Alam</surname><given-names>MK</given-names></name><name><surname>Aldajani</surname><given-names>A</given-names></name><name><surname>Alahmari</surname><given-names>A</given-names></name><name><surname>Alanazi</surname><given-names>A</given-names></name><name><surname>Stoddart</surname><given-names>M</given-names></name><etal/></person-group> <article-title>Dental robotics: a disruptive technology</article-title>. <source>Sensors</source>. (<year>2021</year>) <volume>21</volume>:<fpage>3308</fpage>. <pub-id pub-id-type="doi">10.3390/s21103308</pub-id><pub-id pub-id-type="pmid">34064548</pub-id></citation></ref>
<ref id="B38"><label>38.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Yeshwante</surname><given-names>B</given-names></name><name><surname>Baig</surname><given-names>N</given-names></name><name><surname>Tambake</surname><given-names>SS</given-names></name><name><surname>Tambake</surname><given-names>R</given-names></name><name><surname>Patil</surname><given-names>V</given-names></name><name><surname>Rathod</surname><given-names>R</given-names></name></person-group>. <article-title>Mastering dental implant placement: a review</article-title>. <source>J. Appl. Dent. Med. Sci</source>. (<year>2017</year>) <volume>3</volume>:<fpage>220</fpage>&#x2013;<lpage>7</lpage>.</citation></ref>
<ref id="B39"><label>39.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Woo</surname><given-names>S-Y</given-names></name><name><surname>Lee</surname><given-names>S-J</given-names></name><name><surname>Yoo</surname><given-names>J-Y</given-names></name><name><surname>Han</surname><given-names>J-J</given-names></name><name><surname>Hwang</surname><given-names>S-J</given-names></name><name><surname>Huh</surname><given-names>K-H</given-names></name><etal/></person-group> <article-title>Autonomous bone reposition around anatomical landmark for robot-assisted orthognathic surgery</article-title>. <source>Journal of Cranio-Maxillofacial Surgery</source>. (<year>2017</year>) <volume>45</volume>:<fpage>1980</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1016/j.jcms.2017.09.001</pub-id><pub-id pub-id-type="pmid">29042168</pub-id></citation></ref>
<ref id="B40"><label>40.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Ma</surname><given-names>Q</given-names></name><name><surname>Kobayashi</surname><given-names>E</given-names></name><name><surname>Wang</surname><given-names>J</given-names></name><name><surname>Hara</surname><given-names>K</given-names></name><name><surname>Suenaga</surname><given-names>H</given-names></name><name><surname>Sakuma</surname><given-names>I</given-names></name><etal/></person-group> <article-title>Development and preliminary evaluation of an autonomous surgical system for oral and maxillofacial surgery</article-title>. <source>Int J Med Robot</source>. (<year>2019</year>) <volume>15</volume>:<fpage>e1997</fpage>. <pub-id pub-id-type="doi">10.1002/rcs.1997</pub-id><pub-id pub-id-type="pmid">30900789</pub-id></citation></ref>
<ref id="B41"><label>41.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Zhang</surname><given-names>J</given-names></name><name><surname>Wang</surname><given-names>W</given-names></name><name><surname>Cai</surname><given-names>Y</given-names></name><name><surname>Li</surname><given-names>J</given-names></name><name><surname>Zeng</surname><given-names>Y</given-names></name><name><surname>Chen</surname><given-names>L</given-names></name><etal/></person-group> <article-title>A novel single-arm stapling robot for oral and maxillofacial surgery&#x2014;design and verification</article-title>. <source>IEEE Robot Autom Lett</source>. (<year>2022</year>) <volume>7</volume>:<fpage>1348</fpage>&#x2013;<lpage>55</lpage>. <pub-id pub-id-type="doi">10.1109/LRA.2021.3137891</pub-id></citation></ref>
<ref id="B42"><label>42.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fang</surname><given-names>G</given-names></name><name><surname>Chow</surname><given-names>MCK</given-names></name><name><surname>Ho</surname><given-names>JDL</given-names></name><name><surname>He</surname><given-names>Z</given-names></name><name><surname>Wang</surname><given-names>K</given-names></name><name><surname>Ng</surname><given-names>TC</given-names></name><etal/></person-group> <article-title>Soft robotic manipulator for intraoperative MRI-guided transoral laser microsurgery</article-title>. <source>Sci Robot</source>. (<year>2021</year>) <volume>6</volume>:<fpage>eabg5575</fpage>. <pub-id pub-id-type="doi">10.1126/scirobotics.abg5575</pub-id><pub-id pub-id-type="pmid">34408096</pub-id></citation></ref>
<ref id="B43"><label>43.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Zhang</surname><given-names>Y-D</given-names></name><name><surname>Zhao</surname><given-names>Z-F</given-names></name><name><surname>Lu</surname><given-names>P-J</given-names></name><name><surname>Wang</surname><given-names>Y</given-names></name><name><surname>Song</surname><given-names>R-J</given-names></name><name><surname>Lu</surname><given-names>J-L</given-names></name></person-group>. <article-title>Robotic system approach for complete denture manufacturing</article-title>. <source>IEEE ASME Trans Mechatron</source>. (<year>2002</year>) <volume>7</volume>:<fpage>392</fpage>&#x2013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1109/TMECH.2002.802718</pub-id></citation></ref>
<ref id="B44"><label>44.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Jiang</surname><given-names>J-G</given-names></name><name><surname>Zhang</surname><given-names>Y-D</given-names></name></person-group>. <article-title>Motion planning and synchronized control of the dental arch generator of the tooth-arrangement robot: motion planning and synchronized control of the dental arch generator</article-title>. <source>Int J Med Robotics Comput Assist Surg</source>. (<year>2013</year>) <volume>9</volume>:<fpage>94</fpage>&#x2013;<lpage>102</lpage>. <pub-id pub-id-type="doi">10.1002/rcs.1451</pub-id></citation></ref>
<ref id="B45"><label>45.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Alford</surname><given-names>TJ</given-names></name><name><surname>Roberts</surname><given-names>WE</given-names></name><name><surname>Hartsfield</surname><given-names>JK</given-names></name><name><surname>Eckert</surname><given-names>GJ</given-names></name><name><surname>Snyder</surname><given-names>RJ</given-names></name></person-group>. <article-title>Clinical outcomes for patients finished with the SureSmile<sup>TM</sup> method compared with conventional fixed orthodontic therapy</article-title>. <source>Angle Orthod</source>. (<year>2011</year>) <volume>81</volume>:<fpage>383</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.2319/071810-413.1</pub-id><pub-id pub-id-type="pmid">21261488</pub-id></citation></ref>
<ref id="B46"><label>46.</label><citation citation-type="confproc"><person-group person-group-type="author"><name><surname>Burdea</surname><given-names>GC</given-names></name><name><surname>Dunn</surname><given-names>SM</given-names></name><name><surname>Immendorf</surname><given-names>C</given-names></name></person-group>. <conf-name>Robotic system for dental subtraction radiography</conf-name>. <conf-name>In: proceedings. 1991 IEEE international conference on robotics and automation</conf-name>; <conf-loc>Sacramento, CA, USA</conf-loc>: <publisher-name>IEEE Comput. Soc. Press</publisher-name> (<year>1991</year>). p. <fpage>2056</fpage>&#x2013;<lpage>62</lpage></citation></ref>
<ref id="B47"><label>47.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wu</surname><given-names>J</given-names></name><name><surname>Hui</surname><given-names>W</given-names></name><name><surname>Huang</surname><given-names>J</given-names></name><name><surname>Luan</surname><given-names>N</given-names></name><name><surname>Lin</surname><given-names>Y</given-names></name><name><surname>Zhang</surname><given-names>Y</given-names></name><etal/></person-group> <article-title>The feasibility of robot-assisted chin osteotomy on skull models: comparison with surgical guides technique</article-title>. <source>JCM</source>. (<year>2022</year>) <volume>11</volume>:<fpage>6807</fpage>. <pub-id pub-id-type="doi">10.3390/jcm11226807</pub-id><pub-id pub-id-type="pmid">36431284</pub-id></citation></ref>
<ref id="B48"><label>48.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hwang</surname><given-names>G</given-names></name><name><surname>Paula</surname><given-names>AJ</given-names></name><name><surname>Hunter</surname><given-names>EE</given-names></name><name><surname>Liu</surname><given-names>Y</given-names></name><name><surname>Babeer</surname><given-names>A</given-names></name><name><surname>Karabucak</surname><given-names>B</given-names></name><etal/></person-group> <article-title>Catalytic antimicrobial robots for biofilm eradication</article-title>. <source>Sci Robot</source>. (<year>2019</year>) <volume>4</volume>:<fpage>eaaw2388</fpage>. <pub-id pub-id-type="doi">10.1126/scirobotics.aaw2388</pub-id><pub-id pub-id-type="pmid">31531409</pub-id></citation></ref>
<ref id="B49"><label>49.</label><citation citation-type="confproc"><person-group person-group-type="author"><name><surname>Vela-Anton</surname><given-names>P</given-names></name><name><surname>Nina</surname><given-names>C</given-names></name><name><surname>Ticllacuri</surname><given-names>V</given-names></name><name><surname>Shah</surname><given-names>D</given-names></name><name><surname>Tincopa</surname><given-names>JP</given-names></name><name><surname>Llontop</surname><given-names>M</given-names></name><etal/></person-group> <conf-name>Borjibot: a soft robotic device performing pressure and torsional stimuli for neonates oral-motor rehabilitation</conf-name>. <conf-name>In: 2020 8th IEEE RAS/EMBS international conference for biomedical robotics and biomechatronics (BioRob)</conf-name>; <conf-loc>New York City, NY, USA</conf-loc>: <publisher-name>IEEE</publisher-name> (<year>2020</year>). p. <fpage>403</fpage>&#x2013;<lpage>9</lpage></citation></ref>
<ref id="B50"><label>50.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kasimoglu</surname><given-names>Y</given-names></name><name><surname>Kocaaydin</surname><given-names>S</given-names></name><name><surname>Karsli</surname><given-names>E</given-names></name><name><surname>Esen</surname><given-names>M</given-names></name><name><surname>Bektas</surname><given-names>I</given-names></name><name><surname>Ince</surname><given-names>G</given-names></name><etal/></person-group> <article-title>Robotic approach to the reduction of dental anxiety in children</article-title>. <source>Acta Odontol Scand</source>. (<year>2020</year>) <volume>78</volume>:<fpage>474</fpage>&#x2013;<lpage>80</lpage>. <pub-id pub-id-type="doi">10.1080/00016357.2020.1800084</pub-id><pub-id pub-id-type="pmid">32730719</pub-id></citation></ref>
<ref id="B51"><label>51.</label><citation citation-type="confproc"><person-group person-group-type="author"><name><surname>Sakaeda</surname><given-names>G</given-names></name><name><surname>Takanishi</surname><given-names>A</given-names></name><name><surname>Ishii</surname><given-names>H</given-names></name></person-group>. <conf-name>Development of automatic teeth cleaning robot with maltipule motion of brushes</conf-name>. <conf-name>In: 2021 IEEE/ASME international conference on advanced intelligent mechatronics (AIM)</conf-name>; <conf-loc>Delft, Netherlands</conf-loc>: <publisher-name>IEEE</publisher-name> (<year>2021</year>). p. <fpage>81</fpage>&#x2013;<lpage>5</lpage></citation></ref>
<ref id="B52"><label>52.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Zhao</surname><given-names>R</given-names></name><name><surname>Zhang</surname><given-names>HZ</given-names></name><name><surname>Wu</surname><given-names>ZZ</given-names></name><name><surname>Zhang</surname><given-names>Z</given-names></name><name><surname>Liu</surname><given-names>L</given-names></name><name><surname>Gan</surname><given-names>ZX</given-names></name><etal/></person-group> <article-title>A self-service robot system design for early diagnosis of oral diseases and oral cleaning</article-title>. <source>Hainan Med J</source>. (<year>2018</year>) <volume>29</volume>:<fpage>3348</fpage>&#x2013;<lpage>50</lpage>. <comment>(in Chinese)</comment>. <pub-id pub-id-type="doi">10.1080/00016357.2020.1800084</pub-id></citation></ref>
<ref id="B53"><label>53.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Zhou</surname><given-names>H</given-names></name><name><surname>Mayorga-Martinez</surname><given-names>CC</given-names></name><name><surname>Pan&#x00E9;</surname><given-names>S</given-names></name><name><surname>Zhang</surname><given-names>L</given-names></name><name><surname>Pumera</surname><given-names>M</given-names></name></person-group>. <article-title>Magnetically driven micro and nanorobots</article-title>. <source>Chem Rev</source>. (<year>2021</year>) <volume>121</volume>:<fpage>4999</fpage>&#x2013;<lpage>5041</lpage>. <pub-id pub-id-type="doi">10.1021/acs.chemrev.0c01234</pub-id><pub-id pub-id-type="pmid">33787235</pub-id></citation></ref>
<ref id="B54"><label>54.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Milner</surname><given-names>MN</given-names></name><name><surname>Anania</surname><given-names>EC</given-names></name><name><surname>Candelaria-Oquendo</surname><given-names>K</given-names></name><name><surname>Rice</surname><given-names>S</given-names></name><name><surname>Winter</surname><given-names>SR</given-names></name><name><surname>Ragbir</surname><given-names>NK</given-names></name></person-group>. <article-title>Patient perceptions of new robotic technologies in clinical restorative dentistry</article-title>. <source>J Med Syst</source>. (<year>2020</year>) <volume>44</volume>:<fpage>33</fpage>. <pub-id pub-id-type="doi">10.1007/s10916-019-1488-x</pub-id></citation></ref>
<ref id="B55"><label>55.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Chen</surname><given-names>X</given-names></name><name><surname>Liao</surname><given-names>B</given-names></name><name><surname>Cheng</surname><given-names>L</given-names></name><name><surname>Peng</surname><given-names>X</given-names></name><name><surname>Xu</surname><given-names>X</given-names></name><name><surname>Li</surname><given-names>Y</given-names></name><etal/></person-group> <article-title>The microbial coinfection in COVID-19</article-title>. <source>Appl Microbiol Biotechnol</source>. (<year>2020</year>) <volume>104</volume>:<fpage>7777</fpage>&#x2013;<lpage>85</lpage>. <pub-id pub-id-type="doi">10.1007/s00253-020-10814-6</pub-id><pub-id pub-id-type="pmid">32780290</pub-id></citation></ref>
<ref id="B56"><label>56.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kampf</surname><given-names>G</given-names></name><name><surname>Scheithauer</surname><given-names>S</given-names></name><name><surname>Lemmen</surname><given-names>S</given-names></name><name><surname>Saliou</surname><given-names>P</given-names></name><name><surname>Suchomel</surname><given-names>M</given-names></name></person-group>. <article-title>COVID-19-associated shortage of alcohol-based hand rubs, face masks, medical gloves, and gowns: proposal for a risk-adapted approach to ensure patient and healthcare worker safety</article-title>. <source>J Hosp Infect</source>. (<year>2020</year>) <volume>105</volume>:<fpage>424</fpage>&#x2013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1016/j.jhin.2020.04.041</pub-id><pub-id pub-id-type="pmid">32360355</pub-id></citation></ref>
<ref id="B57"><label>57.</label><citation citation-type="other"><collab>STEM students design initial prototype for remote robotic dentistry</collab>. <comment>Available at:</comment> <ext-link ext-link-type="uri" xlink:href="https://www.dentistryiq.com/dentistry/article/14292589/stem-students-design-initial-prototype-for-remote-robotic-dentistry">https://www.dentistryiq.com/dentistry/article/14292589/stem-students-design-initial-prototype-for-remote-robotic-dentistry</ext-link> (<comment>Accessed July 02, 2023</comment>).</citation></ref>
<ref id="B58"><label>58.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Linn</surname><given-names>TY</given-names></name><name><surname>Salamanca</surname><given-names>E</given-names></name><name><surname>Aung</surname><given-names>LM</given-names></name><name><surname>Huang</surname><given-names>T</given-names></name><name><surname>Wu</surname><given-names>Y</given-names></name><name><surname>Chang</surname><given-names>W</given-names></name></person-group>. <article-title>Accuracy of implant site preparation in robotic navigated dental implant surgery</article-title>. <source>Clin Implant Dent Rel Res</source>. (<year>2023</year>):<fpage>cid.13224</fpage>. <pub-id pub-id-type="doi">10.1111/cid.13224</pub-id></citation></ref>
<ref id="B59"><label>59.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Van Riet</surname><given-names>TCT</given-names></name><name><surname>Chin Jen Sem</surname><given-names>KTH</given-names></name><name><surname>Ho</surname><given-names>J-PTF</given-names></name><name><surname>Spijker</surname><given-names>R</given-names></name><name><surname>Kober</surname><given-names>J</given-names></name><name><surname>De Lange</surname><given-names>J</given-names></name></person-group>. <article-title>Robot technology in dentistry, part one of a systematic review: literature characteristics</article-title>. <source>Dent Mater</source>. (<year>2021</year>) <volume>37</volume>:<fpage>1217</fpage>&#x2013;<lpage>26</lpage>. <pub-id pub-id-type="doi">10.1016/j.dental.2021.06.001</pub-id><pub-id pub-id-type="pmid">34158195</pub-id></citation></ref>
<ref id="B60"><label>60.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Adel</surname><given-names>S</given-names></name><name><surname>Zaher</surname><given-names>A</given-names></name><name><surname>El Harouni</surname><given-names>N</given-names></name><name><surname>Venugopal</surname><given-names>A</given-names></name><name><surname>Premjani</surname><given-names>P</given-names></name><name><surname>Vaid</surname><given-names>N</given-names></name></person-group>. <article-title>Robotic applications in orthodontics: changing the face of contemporary clinical care</article-title>. <source>BioMed Res Int</source>. (<year>2021</year>) <volume>2021</volume>:<fpage>1</fpage>&#x2013;<lpage>16</lpage>. <pub-id pub-id-type="doi">10.1155/2021/9954615</pub-id><pub-id pub-id-type="pmid">35465048</pub-id></citation></ref>
<ref id="B61"><label>61.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Xu</surname><given-names>C</given-names></name><name><surname>Lin</surname><given-names>L</given-names></name><name><surname>Zhou</surname><given-names>C</given-names></name><name><surname>Xie</surname><given-names>L</given-names></name></person-group>. <article-title>A compact surgical robot system for craniomaxillofacial surgery and its preliminary study</article-title>. <source>J Craniofac Surg</source>. (<year>2021</year>) <volume>32</volume>:<fpage>101</fpage>&#x2013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1097/SCS.0000000000007022</pub-id><pub-id pub-id-type="pmid">32956317</pub-id></citation></ref>
<ref id="B62"><label>62.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Tao</surname><given-names>B</given-names></name><name><surname>Feng</surname><given-names>Y</given-names></name><name><surname>Fan</surname><given-names>X</given-names></name><name><surname>Zhuang</surname><given-names>M</given-names></name><name><surname>Chen</surname><given-names>X</given-names></name><name><surname>Wang</surname><given-names>F</given-names></name><etal/></person-group> <article-title>Accuracy of dental implant surgery using dynamic navigation and robotic systems: an in vitro study</article-title>. <source>J Dent</source>. (<year>2022</year>) <volume>123</volume>:<fpage>104170</fpage>. <pub-id pub-id-type="doi">10.1016/j.jdent.2022.104170</pub-id><pub-id pub-id-type="pmid">35679989</pub-id></citation></ref>
<ref id="B63"><label>63.</label><citation citation-type="other"><collab>Boston Dental Clinic Deploys Autonomous Robots to Eradicate Covid-19 Virus</collab>. <comment>Available at:</comment> <ext-link ext-link-type="uri" xlink:href="https://www.dentalnews.com/2020/06/08/boston-dental-clinic-uvd-robots-covid-19-virus/">https://www.dentalnews.com/2020/06/08/boston-dental-clinic-uvd-robots-covid-19-virus/</ext-link> (<comment>Accessed July 15, 2023</comment>).</citation></ref>
<ref id="B64"><label>64.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cimolai</surname><given-names>N</given-names></name></person-group>. <article-title>Environmental and decontamination issues for human coronaviruses and their potential surrogates</article-title>. <source>J Med Virol</source>. (<year>2020</year>) <volume>92</volume>:<fpage>2498</fpage>&#x2013;<lpage>510</lpage>. <pub-id pub-id-type="doi">10.1002/jmv.26170</pub-id><pub-id pub-id-type="pmid">32530505</pub-id></citation></ref>
<ref id="B65"><label>65.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hong</surname><given-names>H</given-names></name><name><surname>Shin</surname><given-names>W</given-names></name><name><surname>Oh</surname><given-names>J</given-names></name><name><surname>Lee</surname><given-names>S</given-names></name><name><surname>Kim</surname><given-names>T</given-names></name><name><surname>Lee</surname><given-names>W</given-names></name><etal/></person-group> <article-title>Standard for the quantification of a sterilization effect using an artificial intelligence disinfection robot</article-title>. <source>Sensors</source>. (<year>2021</year>) <volume>21</volume>:<fpage>7776</fpage>. <pub-id pub-id-type="doi">10.3390/s21237776</pub-id><pub-id pub-id-type="pmid">34883781</pub-id></citation></ref>
<ref id="B66"><label>66.</label><citation citation-type="other"><collab>IUVA</collab>. <comment><italic>What is the UVC dose for killing or disabling the COVID-19 virus?</italic> Available at:</comment> <ext-link ext-link-type="uri" xlink:href="https://www.iuva.org/iuva-covid19-faq">https://www.iuva.org/iuva-covid19-faq</ext-link> (<comment>Accessed: June 06, 2023</comment>).</citation></ref>
<ref id="B67"><label>67.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Buonanno</surname><given-names>M</given-names></name><name><surname>Welch</surname><given-names>D</given-names></name><name><surname>Shuryak</surname><given-names>I</given-names></name><name><surname>Brenner</surname><given-names>DJ</given-names></name></person-group>. <article-title>Far-UVC light (222&#x2009;nm) efficiently and safely inactivates airborne human coronaviruses</article-title>. <source>Sci Rep</source>. (<year>2020</year>) <volume>10</volume>(<issue>1</issue>):<fpage>10285</fpage>. <pub-id pub-id-type="doi">10.1038/s41598-020-67211-2</pub-id><pub-id pub-id-type="pmid">32581288</pub-id></citation></ref></ref-list>
</back>
</article>