AUTHOR=Liu Xuejian , Wang Qi , Ma Yang , Xiao Xinhua , Zhao Xue , Tang Hailin , Gopinath Divya , Wang Chao TITLE=Editorial: The insights of multi-omics into the microenvironment after tumor metastasis: a paradigm shift in molecular targeting modeling and immunotherapy for advanced cancer patients JOURNAL=Frontiers in Oncology VOLUME=Volume 15 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1749178 DOI=10.3389/fonc.2025.1749178 ISSN=2234-943X