AUTHOR=Yang Rong , Zhao Juan , Zhou Lin TITLE=Case Report: Imaging and pathological analysis of intra-abdominal aggressive fibromatosis with abscess JOURNAL=Frontiers in Oncology VOLUME=Volume 15 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1692823 DOI=10.3389/fonc.2025.1692823 ISSN=2234-943X ABSTRACT=This study investigates the imaging diagnosis and differential diagnosis of intra-abdominal aggressive fibromatosis (IAF) complicated by acute infection. Aggressive fibromatosis is a rare mesenchymal tumor of unclear etiology, potentially associated with genetic factors, hormonal levels, trauma, and other factors. Due to its clinical rarity and nonspecific imaging manifestations, preoperative diagnosis is challenging and prone to misdiagnosis, particularly in the more complex presentation of IAF. We present a rare case of IAF accompanied by abscess formation, analyzing its imaging and pathological features alongside clinical manifestations, and discuss diagnostic and therapeutic strategies.