Front. Oncol.Frontiers in OncologyFront. Oncol.2234-943XFrontiers Media S.A.10.3389/fonc.2025.1641204OncologyCorrectionCorrection: circDENND4C serves as a sponge for miR-200b to drive non-small cell lung cancer advancement by regulating MMP-9 expressionLvYaming12†WangLan12†ZhangYunhui12WeiDong3*HuYajie12*1Department of Respiratory Medicine, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China2Department of Respiratory Medicine, The First People’s Hospital of Yunnan Province, Kunming, China3Department of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical University, Kunming, China
Edited and reviewed by: Cecilia Ana Suarez, National Scientific and Technical Research Council (CONICET), Argentina
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A Correction on circDENND4C serves as a sponge for miR-200b to drive non-small cell lung cancer advancement by regulating MMP-9 expression By Lv Y, Wang L, Zhang Y, Wei D and Hu Y (2025) Front. Oncol. 15:1441384. doi: 10.3389/fonc.2025.1441384circDENND4CmiR-200bMMP-9non-small cell lung cancer (NSCLC)tumor progressionsection-in-acceptanceThoracic Oncology
There was a mistake in Figure 5B and Figure 6B as published. In Figure 5B, due to the author’s unintentionally arranged error, the flow cytometry image of apoptosis results of the miR-200b-Knockdown group was incorrected as the image of the Mock group. In Figure 6B, due to the author adopted the same photoing techniques to obtain many high quality pictures for the migration and invasion experiments, the original picture sources of the Plasmid-Control group and the miR-200b-Over group were unintentionally misused when the author selected the photos and arranged them. The corrected [Figure 5B and Figure 6B] and its caption “Figure 5B Flow cytometry was used to analyze the apoptotic rate of A549 cells transfected with the overexpression and knockdown vectors of circDENN4C, miR-200b and MMP-9. The data are presented as the mean ± SEM.” and “Figure 6B The invasion of A549 cells transfected with the indicated vectors was assessed by transwell invasion assay. The data are presented as the mean ± SEM.” appear below.
Influences of the circDENND4C/miR-200b/MMP-9 regulatory axis on cell cycle and cell death of A549 cells. (A) Flow cytometry was used to analyze the cell cycle in A549 cells transfected with the overexpression and knockdown vectors of circDENN4C, miR-200b, and MMP-9. (B) Flow cytometry was used to analyze the apoptotic rate of A549 cells transfected with the overexpression and knockdown vectors of circDENN4C, miR-200b and MMP-9.The data are presented as the mean ± SEM. The p-values at the bottom of the bar chart are obtained by ANOVA among multiple groups, while the NS and detailed p-values labeled in the bar chart are the results of post-ANOVA comparison. NS, not significant.
Charts showing cell cycle progression and cell death under various conditions. Part A depicts cell proliferation with flow cytometry plots and a bar graph comparing G1, S, and G2 phase percentages. Part B displays total cell death with scatter plots and a bar chart illustrating early apoptosis, late apoptosis, and necrosis rates. Statistical significance between different treatments is indicated, with some showing “NS” for not significant.
The circDENND4C/miR-200b/MMP-9 axis regulated NSCLC cell migration and invasion. (A) The migration of A549 cells transfected with the indicated vectors was assessed by the transwell migration assay. (B) The invasion of A549 cells transfected with the indicated vectors was assessed by transwell invasion assay. The data are presented as the mean ± SEM. The p-values on the right side of the bar chart are obtained by ANOVA among multiple groups, while the detailed p-values labeled in the bar chart are the results of post-ANOVA comparison. NS, not significant.
Microscopy images and bar charts show cell migration and invasion under different conditions. Images A and B depict various treatments: Mock, Plasmid-Control, circDENN4C-Over, circDENN4C-Knockdown, miR-200b-Over, miR-200b-Knockdown, MMP-9-Over, and si-MMP-9. Bar charts compare the number of migratory and invasive cells with statistical significance marked by P-values.
The original article has been updated.
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