AUTHOR=Forster Marie , Wuerstlein Rachel , Koenig Alexander , Stefan Alexandra , Wiegershausen Elisa , Batz Falk , Trillsch Fabian , Mahner Sven , Harbeck Nadia , Chelariu-Raicu Anca TITLE=Health-related quality of life and patient-centred outcomes with COVID-19 vaccination in patients with breast cancer and gynaecological malignancies JOURNAL=Frontiers in Oncology VOLUME=Volume 13 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1217805 DOI=10.3389/fonc.2023.1217805 ISSN=2234-943X ABSTRACT=Introduction: Safety and tolerability of COVID-19 vaccines were demonstrated by several clinical trials which led to the first FDA/EMA approvals in 2021. Because of mass immunizations, most social restrictions were waived with effects on quality of life. Therefore, our a-priori hypothesis was that COVID-19 vaccination impacted the health-related quality of life (HR-QoL) in patients with breast and gynecological cancer. Methods: From March 15 th until August 11 th , 2022, fully vaccinated patients with breast and gynecological cancer treated in the oncological outpatient clinics of the