Front. Oncol. Frontiers in Oncology Front. Oncol. 2234-943X Frontiers Media S.A. 10.3389/fonc.2023.1208728 Oncology Correction Corrigendum: MicroRNA-153 decreases tryptophan catabolism and inhibits angiogenesis in bladder cancer by targeting indoleamine 2,3-dioxygenase 1 Zhang Wentao 1 2 † Mao Shiyu 1 † Shi Donghui 3 † Zhang Junfeng 1 * Zhang Ziwei 1 Guo Yadong 1 Wu Yuan 1 2 Wang Ruiliang 1 Wang Longsheng 1 Huang Yong 4 * Yao Xudong 1 2 * 1 Department of Urology, Shanghai Tenth People’s Hospital, Tongji University, Shanghai, China 2 Anhui Medical University, Shanghai Clinical College, Hefei, China 3 Department of Urology, Suzhou Wuzhong People’s Hospital, Wuzhong, China 4 Department of Urology, The First Affliated Hospital of Inner Mongolia Medical University, Hohhot, China

Edited and Reviewed by: Lawrence Wing Chi Chan, Hong Kong Polytechnic University, Hong Kong SAR, China

*Correspondence: Junfeng Zhang, 1610655@tongji.edu.cn; Yong Huang, huangyongmedical@outlook.com; Xudong Yao, yaoxudong1967@163.com

†These authors have contributed equally to this work

 22 05 2023 2023 13 1208728 19 04 2023 02 05 2023 Copyright © 2023 Zhang, Mao, Shi, Zhang, Zhang, Guo, Wu, Wang, Wang, Huang and Yao 2023 Zhang, Mao, Shi, Zhang, Zhang, Guo, Wu, Wang, Wang, Huang and Yao

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 A corrigendum on MicroRNA-153 decreases tryptophan catabolism and inhibits angiogenesis in bladder cancer by targeting indoleamine 2,3-dioxygenase 1 by Zhang W, Mao S, Shi D, Zhang J, Zhang Z, Guo Y, Wu Y, Wang R, Wang L, Huang Y and Yao X(2019). Front. Oncol. 9:619. doi: 10.3389/fonc.2019.00619. bladder cancer miR-153 tryptophan catabolism angiogenesis indoleamine 2 3-dioxygenase 1 section-in-acceptance Molecular and Cellular Oncology

In the published article, there was a there was an error in Figures 2 , 5 as published. We mistakenly used the same image of clone formation in Figure 2E (T24-miR-153) and Figure 5B (UMUC3-Si-IDO1) due to layer overlays. Furthermore, in the transwell section of Figure 2 , we found a minor error in the UMUC3-miR-153(G) and T24-miR-NC(H) due to incorrect use of images. We repeated these experiments and corrected the results. The corrected Figures 2 , 5 appear below.

miR-153 inhibits bladder cancer growth in vitro and in vivo by promoting tumor cell apoptosis, migration, invasion, and EMT. (A) Cell viability CCK-8 assay. T24 and UMUC3 cells were transfected with miR-153 mimics or negative control and then subjected to the CCK-8 assay. (B) Nude mouse xenograft assay. Stably miR-153 expressing mimics or negative control bladder cancer cells were subcutaneously injected into nude mice and monitored for 40 days for tumor cell xenograft formation and growth. (C) Tumor cell xenograft growth curves. (D) Tumor cell xenograft weight. (E) Colony formation assay. T24 and UMUC3 cells were transfected with miR-153 mimics or negative control and then subjected to tumor cell colony formation assay (x 200). (F) Western blot. Expression levels of EMT-associated markers in miR-153 mimics or negative control transfected T24 and UMUC3 cells were evaluated by using Western blot analysis. (G) Transwell tumor cell migration assay. (H) Transwell tumor cell invasion assay. (I) Flow cytometric Annexin V-PI double staining assay. *P < 0.05.

IDO1 knockdown inhibits bladder cancer cell proliferation, migration, and invasion, and induced apoptosis and modulation of EMT markers. (A) Cell viability CCK-8assay. T24 and UMUC3 cells were transfected with IDO1 or negative control siRNA and then subjected to the CCK-8 assay. (B) Colony formation assay. T24 and UMUC3 cells were transfected with IDO1 or negative control siRNA and then subjected to colony formation (x 200) and Transwell assays. (C) Western blot. Levels of the EMT-associated markers were analyzed in T24 and UMUC3 cells after IDO1 knockdown by using Western blot. (D) Transwell migration assay. (E) Transwell invasion assay. (F) Flow cytometric Annexin V-PI double staining assay in T24 and UMUC3 cells after knockdown of IDO1. *P < 0.05.

There was also an error in Figure 7 . We missed labeling the names of T24 and UMUC3 cell lines in panels C and D. The corrected Figure 7 appears below.

miR-153 targets IDO1 and modulates angiogenesis through IL6/STAT3/VEGF signaling. (A, B) ELISA. IL_6 expression in T24 and UMUC3 cells (overexpression of miR-153 or knockdown of IDO1 and their respective negative controls) were analyzed using ELISA. (C, D) Western blot. T24 and UMUC3 cells (overexpression of miR-153 or knockdown of IDO1 and their respective negative controls) were pretreated with 100 ng/ml of IL-6 for 48 h and then subjected to Western blot analysis of STAT3, p-STAT3, and VEGF. *p<0.05.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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