AUTHOR=Ye Suna , Fang Qiqi , Yao Jinyu , Xing Jianqiang , Tang Shibo , Ma Jacey Hongjie 

TITLE=Intravitreal Ranibizumab Had Limited Effect on Cystoid Macular Edema Due to Albumin-Bound Paclitaxel: A Case Report and Literature Review

JOURNAL=Frontiers in Oncology

VOLUME=Volume 11 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.773540

DOI=10.3389/fonc.2021.773540

ISSN=2234-943X

ABSTRACT=Angiographically silent macular cystoid edema (CME) is a rare complication from nab-paclitaxel. Here, we report a 45-year-old woman with breast cancer who developed cystic macular edema after several months of treatment with nab-paclitaxel. With cessation of nab-paclitaxel and intravitreal ranibizumab treatment, her macular edema did not improve. Then, brinzolamide eye drops were prescribed and one month later her vision improved and macular edema was significantly reduced. Finally, we review other cases of macular cystoid edema induced by nab-paclitaxel that have been reported in the literature and discuss the underlying pathogenesis of nab-paclitaxel-induced CME.