AUTHOR=Escudero-Vilaplana Vicente , Calles Antonio , Collado-Borrell Roberto , Belén Marzal-Alfaro María , Polanco Carlos , Garrido Carmen , Suarez Jorge , Ortiz Aurora , Appierto Marilena , Comellas Marta , Lizán Luis 

TITLE=Standardizing Health Outcomes for Lung Cancer. Adaptation of the International Consortium for Health Outcomes Measurement Set to the Spanish Setting

JOURNAL=Frontiers in Oncology

VOLUME=Volume 10 - 2020

YEAR=2020

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.01645

DOI=10.3389/fonc.2020.01645

ISSN=2234-943X

ABSTRACT=Purpose
Lung cancer (LC) and its treatment impose a significant burden on patients’ life. However, patient-centered outcomes are rarely collected during patient follow-up. Filling this gap, the International Consortium for Health Outcomes Measurement (ICHOM) developed a standard set of variables for newly diagnosed LC patients. In order to facilitate the use of this standard set, the project aims to adapt it to the Spanish setting. 
Methods
The variables (instrument and periodicity) to be included in Spanish standard set were selected through consensus during 4 nominal groups (13 oncologists, 14 hospital pharmacists, 4 hospital managers and 3 LC patients), under the supervision of a Scientific Committee (1 oncologist, 3 hospital pharmacists, 2 LC patients advocates).
Results
The variables agreed upon included: 1) case-mix: demographic [age, sex, education and social-family support], clinical [weight loss, smoking status, comorbidities (Charlson index), pulmonary function (FEV-1)], tumor [histology, clinical and pathological stage (TNM), EGFR, ALK, ROS-1, PD-L1] and treatment factors [intent and completion] and 2) outcomes: degree of health [performance status (ECOG) and quality-of-life (EQ-5D, LCSS)], survival [overall survival and cause of death], quality of death [place of death, end-of-life care and palliative care, death aligned with living will], treatment complications, and others [date of diagnosis and treatment initiation, productivity loss (sick leave)]. 
Conclusion
The adaptation of ICHOM standard set to the Spanish setting pave the way to standardize the collection of variables in LC.