AUTHOR=Shi Xiang , Zhou Weiyan , Xu Mengqiao , Hua Tao , Guan Yihui 
  
TITLE=Successful Treatment for Adult Precursor B-Cell Lymphoblastic Lymphoma Involving Central Nervous System Monitored by 18F-Fluorodeoxyglucose PET/CT Imaging
  
JOURNAL=Frontiers in Oncology
  
VOLUME=Volume 10 - 2020
  
YEAR=2020
  
URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.00334
  
DOI=10.3389/fonc.2020.00334
  
ISSN=2234-943X
  
ABSTRACT=Precursor B-cell lymphoblastic lymphoma(PBLL) is a rare subtype of non-Hodgkin lymphoma originating from B-cell precursors. PBLL as a solitary mass lesion affecting central nervous system(CNS) without leukemic disease at presentation is quite uncommon. Here we report a rare PBLL case with Philadelphia chromosome-positive. The 44-year-old male presented a solitary bulky mass primarily involved left fronto-temporal lobes and extended into infra-temporal fossa. Pretreatment PET/CT imaging showed avid 18F-FDG uptake of the lesion. By aggressive chemotherapy and Imatinib maintenance treatment, the patient achieved and remained in complete remission on another two consecutive PET/CT imaging follow-ups.