Front. Nutr. Frontiers in Nutrition Front. Nutr. 2296-861X Frontiers Media S.A. 10.3389/fnut.2024.1376599 Nutrition Correction Corrigendum: Safe and effective delivery of supplemental iron to healthy adults: a two-phase, randomized, double-blind trial – the safe iron study Lewis Erin D. 1 † Ortega Edwin F. 1 Dao Maria Carlota 1 Barger Kathryn 1 Mason Joel B. 1 Leong John M. 2 Osburne Marcia S. 2 Magoun Loranne 2 Nepveux Felix J. V 2 Chishti Athar H. 3 Schwake Christopher 3 Quynh Anh 3 Gilhooly Cheryl H. 1 Petty Gayle 1 Guo Weimin 1 † Matuszek Gregory 1 Pereira Dora 4 † Reddy Manju 5 Wang Jifan 1 Wu Dayong 1 Meydani Simin N. 1 * Combs Gerald F. Jr. 1 1Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, United States 2Department of Molecular Biology and Microbiology, Tufts University, Boston, MA, United States 3Department of Developmental, Molecular and Chemical Biology, Tufts University, Boston, MA, United States 4Department of Pathology, University of Cambridge, Cambridge, United Kingdom 5Department of Food Science and Human Nutrition, Iowa State University, Ames, IA, United States

Edited and reviewed by: Johannes le Coutre, University of New South Wales, Australia

 *Correspondence: Simin N. Meydani simin.meydani@tufts.edu

†Present addresses: Erin D. Lewis, KGK Science, Inc., London, Ontario, ON, Canada

Weimin Guo, Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, United States

Dora Pereira, Vifor Pharma UK Ltd., Cambridge, England, United Kingdom

 27 02 2024 2024 11 1376599 25 01 2024 12 02 2024 Copyright © 2024 Lewis, Ortega, Dao, Barger, Mason, Leong, Osburne, Magoun, Nepveux V, Chishti, Schwake, Quynh, Gilhooly, Petty, Guo, Matuszek, Pereira, Reddy, Wang, Wu, Meydani and Combs. 2024 Lewis, Ortega, Dao, Barger, Mason, Leong, Osburne, Magoun, Nepveux V, Chishti, Schwake, Quynh, Gilhooly, Petty, Guo, Matuszek, Pereira, Reddy, Wang, Wu, Meydani and Combs

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 A corrigendum on Safe and effective delivery of supplemental iron to healthy adults: a two-phase, randomized, double-blind trial – the safe iron study by Lewis, E. D., Ortega, E. F., Dao, M. C., Barger, K., Mason, J. B., Leong, J. M., Osburne, M. S., Magoun, L., Nepveux, V. F. J., Chishti, A. H., Schwake, C., Quynh, A., Gilhooly, C. H., Petty, G., Guo, W., Matuszek, G., Pereira, D., Reddy, M., Wang, J., Wu, D., Meydani, S. N., and Combs, G. F. (2023). Front. Nutr. 10:1230061. doi: 10.3389/fnut.2023.1230061 iron ferrous sulfate malarial infectivity bacterial proliferation gut inflammation IHAT fungal iron section-at-acceptance Clinical Nutrition

In the published article, there was an error. The error involved an inconsistency between our abstract and discussion regarding the observed effects of one treatment on some secondary outcomes, GI symptoms.

A correction has been made to Abstract, subsection Results.

This section previously stated:

“Supplementation with any form of iron did not affect any primary endpoint. In Phase I, the frequency of gastrointestinal symptoms associated with FS was unaffected by dosing with MNP or weekly administration; but participants taking IHAT more frequently reported abdominal pain (27%, p < 0.008) and nausea (4%, p = 0.009) than those taking FS, while those taking ASP more frequently reported nausea (8%, p = 0.009). Surprisingly, only 9% of participants taking IHAT at 120 mg Fe/day (Phase II) reported abdominal pain and no other group reported that symptom.”

The corrected section appears below:

“Supplementation with any form of iron did not affect any primary endpoint. Regarding secondary endpoints, in Phase I participants taking IHAT more frequently reported abdominal pain (27%, p = 0.008) than other iron forms; those taking the weekly FS dose more frequently reported nausea (20%, P = 0.009) than the other forms and modes of administration. In phase II, no such differences were observed.”

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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