Front. Neurosci. Frontiers in Neuroscience Front. Neurosci. 1662-453X Frontiers Media S.A. 10.3389/fnins.2025.1664442 Neuroscience Correction Correction: Effects of chronic light cycle disruption during adolescence on circadian clock, neuronal activity rhythms, and behavior in mice Bonilla Pablo Shanks Alexandria Nerella Yatin Porcu Alessandra * Department of Drug Discovery and Biomedical Science, University of South Carolina, Columbia, SC, United States

Edited and reviewed by: Chelsea A. Vadnie, Ohio Wesleyan University, United States

 *Correspondence: Alessandra Porcu aporcu@mailbox.sc.edu 08 09 2025 2025 19 1664442 11 07 2025 14 08 2025 Copyright © 2025 Bonilla, Shanks, Nerella and Porcu. 2025 Bonilla, Shanks, Nerella and Porcu

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 A Correction on Effects of chronic light cycle disruption during adolescence on circadian clock, neuronal activity rhythms, and behavior in mice by Bonilla, P., Shanks, A., Nerella, Y., and Porcu, A. (2024). Front. Neurosci. 18:1418694. doi: 10.3389/fnins.2024.1418694 light cycle disruption suprachiasmatic nucleus dentate gyrus medial amygdala somatostatin clock genes neuronal activity avoidance behavior section-at-acceptance Sleep and Circadian Rhythms

There was a mistake in Figure 3C as published. The panel labeled as Control-ZT22 was inadvertently duplicated from the LCD-ZT2 image. The panel labeled as Control-ZT16 was incorrectly selected and actually corresponds to Control-ZT22. This mistake occurred during figure assembly due to confusion while selecting representative figures from our blinded dataset. All data analyses and quantifications were conducted using the correct images, and we have verified that the conclusions of Per1 analysis remain valid and unaffected. The corrected Figure 3 appears below.

Daily expression of Per1, Clock and cFOS in the SCN. Representative confocal micrographs showing (A) Clock (red) and (C) Per1 (green) mRNA expression detected by RNAscope and (E) c-FOS (red) detected by immunofluorescence at ZT2, ZT8, ZT16 and ZT22 in control and LCD mice (Scale bar 50 μm). Line graphs show (B) Clock mRNA expression (F1, 32 = 76.41, p < 0.0001 by two-way ANOVA with Šídák's multiple comparison posttest) and (D) Per1 mRNA expression [F(1, 32) = 10.17, p < 0.0032 by two-way ANOVA with Šídák's multiple comparison posttest] determined by semiquantitative scoring of Clock and Per1 dots and clusters per neuron, and (F) number of c-FOS positive neurons in the SCN [F(1, 32) = 38.01, p < 0.0001 by two-way ANOVA with Šídák's multiple comparison posttest]. Data are shown as mean ± SEM. (Control n = 2 females and n = 2 males; LCD n = 2 females, n = 2 males) for the SCN in a 30-μm section; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, two-way ANOVA (post-hoc test conducted with Šídák's multiple comparison test).

Images A, C, and E show immunofluorescence of mouse brain slices at different time points (ZT 2, 8, 16, 22) for markers Clock (red), Per1 (green), and c-FOS with DAPI (red and blue) in control and LCD groups. Graphs B, D, and F present quantification: clock, Per1 and cFOS peak during the light phase, clock and cFOS show significance difference at ZTs 2 and 8 between control and LCD group.

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