Front. Neurosci. Frontiers in Neuroscience Front. Neurosci. 1662-453X Frontiers Media S.A. 10.3389/fnins.2016.00320 Psychiatry Correction Corrigendum: Commentary: Evaluation of Models of Parkinson's Disease Muñoz Patricia 1 Paris Irmgard 2 Segura-Aguilar Juan 1 * 1Molecular and Clinical Pharmacology, Faculty of Medicine, University of Chile Santiago, Chile 2Departamento de Ciencia Básicas, Facultad de Ciencias, Universidad Santo Tomas Viña del Mar, Chile

Edited and reviewed by: Mark R. Cookson, National Institutes of Health, USA

*Correspondence: Juan Segura-Aguilar jsegura@med.uchile.cl

This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neuroscience

 07 07 2016 2016 10 320 16 05 2016 24 06 2016 Copyright © 2016 Muñoz, Paris and Segura-Aguilar. 2016 Muñoz, Paris and Segura-Aguilar

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 A corrigendum on Commentary: Evaluation of Models of Parkinson's Disease by Muñoz, P., Paris, I., and Segura-Aguilar, J. (2016). Front. Neurosci. 10:161. doi: 10.3389/fnins.2016.00161 dopamine o-quinone dopamine aminochrome neurodegenration astrocytes dopaminergic neurons

It was an error in the structure of dopamine o-quinone published in the commentary on Evaluation of models of Parkinson's disease since the benzene ring contained an extra double bound between the carbonyls. The actual structure of dopamine o-quinone is the correct structure.

Astrocytes protect dopaminergic neurons against aminochrome neurotoxicity. Astrocytes secrete GSTM2 which is internalized by dopaminergic neurons in order to increase their protection against aminochrome. Dopamine oxidation to neuromelanin is a harmless pathway due to the presence of DT-diaphorase and GSTM2 that prevent aminochrome-dependent neurotoxicity by inhibiting the formation of alpha-synuclein (SNCA) neurotoxic oligomers, mitochondrial dysfunction, oxidative stress, autophagy, and proteasome dysfunction and endoplasmic reticulum stress.

 Author contributions

All authors listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication.

 Funding

Supported by University of Chile (ENL014/14).

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.