AUTHOR=Gao Haobo , Bibi Hifsa , Tan Hongtu , Zhang Yiwei , Yang Guofang , Wang Jiabing , Wu Tao 

TITLE=Research progress on risk factors for in-stent restenosis following cerebrovascular stent implantation

JOURNAL=Frontiers in Neurology

VOLUME=Volume 16 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2025.1660202

DOI=10.3389/fneur.2025.1660202

ISSN=1664-2295

ABSTRACT=Transient ischemic attack or ischemic stroke within 6 months is frequently associated with severe carotid stenosis. Carotid stent implantation is a widely employed treatment, but in-stent restenosis (ISR) is a dangerous postoperative complication. Many factors cause in-stent restenosis. Previous studies have indicated that stent type, drug use, patient-specific risk factors, levels of various factors in the patient’s body, surgical procedures, and vascular physiological anatomy can all contribute to its occurrence. This review summarizes the key risk factors for ISR following CAS and briefly discusses related findings in intracranial artery stenting, aiming to inform clinical decision-making in neurointerventional practice.