AUTHOR=Zhang Wensheng , Lin Wen , Wen Yangchun , Lan Haiping , Zhu Minzhen , Zhong Xiaojing , Xing Weifang , Jiang Zhenqin 

TITLE=Efficacy and safety of successful mechanical thrombectomy in elderly patients with anterior circulation large vessel occlusion acute ischemic stroke

JOURNAL=Frontiers in Neurology

VOLUME=Volume 16 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2025.1646081

DOI=10.3389/fneur.2025.1646081

ISSN=1664-2295

ABSTRACT=ObjectiveTo explore the efficacy and safety of successful mechanical thrombectomy (MT) in elderly patients with anterior circulation large vessel occlusion acute ischemic stroke (AIS).MethodsA retrospective analysis was conducted on 437 patients admitted to our hospital from January 2019 to November 2023 who received successful MT because of anterior circulation large vessel occlusion AIS. They were divided into an elderly group (age ≥ 80 years old) and a young group (age<80 years old). Their clinical data were analyzed.ResultsThere were 61 cases in the elderly group and 376 cases in the young group. Before and after propensity score matching analysis, there was no significant difference in any type of cerebral hemorrhage, cerebral hernia, futile recanalization and all-cause mortality between two groups of patients with a p value greater than 0.05.ConclusionThe incidence of any type of cerebral hemorrhage, cerebral hernia, futile recanalization and all-cause mortality in elderly patients with anterior circulation large vessel occlusion AIS was similar to that in young patients. Compared to young patients, MT is also effective and safe in elderly patients.