Front. Neurol.Frontiers in NeurologyFront. Neurol.1664-2295Frontiers Media S.A.10.3389/fneur.2024.1540452NeurologyCorrectionCorrigendum: Cipaglucosidase alfa plus miglustat: linking mechanism of action to clinical outcomes in late-onset Pompe diseaseByrneBarry J.1*ParentiGiancarlo23SchoserBenedikt4van der PloegAns T.5DoHung6FoxBrian7GoldmanMitchell7JohnsonFranklin K.7KangJia8MehtaNickita7MondickJohn9SheikhM. Osman7Sitaraman DasSheela7TuskeSteven7BrudvigJon7WeimerJill M.7MozaffarTahseen101Department of Pediatrics in the College of Medicine, University of Florida, Gainesville, FL, United States2Metabolic Unit, Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy3Telethon Institute of Genetics and Medicine, Pozzuoli, Italy4Friedrich-Baur-Institute, Department of Neurology, LMU University Hospital, LMU Munich, Munich, Germany5Erasmus MC University Medical Center, Rotterdam, Netherlands6M6P-Therapeutics, St Louis, MO, United States7Amicus Therapeutics, Inc., Princeton, NJ, United States8Metrum Research Group, Tariffville, CT, United States9Incyte Corporation, Wilmington, DE, United States10Department of Neurology, University of California, Irvine, Irvine, CA, United States
Edited and reviewed by: Edoardo Malfatti, Hôpitaux Universitaires Henri Mondor, France
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A corrigendum on Cipaglucosidase alfa plus miglustat: linking mechanism of action to clinical outcomes in late-onset Pompe disease by Byrne, B. J., Parenti, G., Schoser, B., van der Ploeg, A. T., Do, H., Fox, B., Goldman, M., Johnson, F. K., Kang, J., Mehta, N., Mondick, J., Sheikh, M. O., Sitaraman Das, S., Tuske, S., Brudvig, J., Weimer, J. M., and Mozaffar. T. (2024). Front. Neurol. 15:1451512. doi: 10.3389/fneur.2024.1451512Pompe diseaseglycogen storage disease type IIlysosomal storage disordersenzyme replacement therapyn-butyldeoxynojirimycinAmicus Therapeuticshttps://doi.org/10.13039/100015362section-at-acceptanceNeuromuscular Disorders and Peripheral Neuropathies
In the published article, there was an error in Figure 13 as published. The error relates to the positive/negative value of some of the numbers on the axes for the lower MMT score and the GSGC total score in Figure 13A. For both lower MMT score and GSGC total score, the axis scale incorrectly read −3, −2, 1, 0, −1, −2, −3 from left to right, whereas the axis scale for lower MMT score should have been −3, −2, −1, 0, 1, 2, 3 and the axis scale for GSGC total score should have been 3, 2, 1, 0, −1, −2, −3. The corrected Figure 13 and its caption appear below.
Change from baseline at week 52 of PROPEL—effect of cipaglucosidase alfa plus miglustat compared with alglucosidase alfa plus placebo in key efficacy outcomes. (A) Forest plot illustrating mean estimated treatment differences between cipaglucosidase alfa plus miglustat versus alglucosidase alfa plus placebo and corresponding 95% CIs are shown for the combined PROPEL study population for each outcome, with units as indicated on the x-axes. For all outcomes, right-sided directionality of treatment differences indicates favorable outcomes for cipaglucosidase alfa plus miglustat compared with alglucosidase alfa plus placebo. (B) The table shows baseline mean values and Week 52 CFBL values for cipaglucosidase alfa plus miglustat and alglucosidase alfa plus placebo. Shaded CFBL indicates nominally significant improvement (green) or nominally significant worsening (red) from baseline (i.e., the 95% CI does not include zero) within each treatment group. The p-values (two-tailed LS mean difference) shown in the far-right column are for the between-group treatment differences illustrated in the forest plot.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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